[ { "id": "Q8R4G0-1.320.320", "start_pos": 320, "end_pos": 320, "uniprot_canonical_ac": "Q8R4G0-1", "length": 539, "uniprot_id": "NTNG1_MOUSE", "protein_name": "Netrin-G1", "refseq_ac": "NP_001156820", "refseq_name": "netrin-G1 isoform b", "gene_name": "Ntng1", "gene_names_uniprotkb": "Ntng1; Kiaa0976; Lmnt1", "gene_names_refseq": "A930010C08Rik; Lmnt1; Ntng1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8R4G0", "url": "https://www.uniprot.org/uniprotkb/Q8R4G0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Capturing site-specific heterogeneity with large-scale N-glycoproteome analysis.", "journal": "Nature communications", "date": "2019", "authors": "Riley NM, Hebert AS, Westphall MS, Coon JJ", "evidence": [ { "database": "GlyConnect", "id": "2532", "url": "https://glyconnect.expasy.org/browser/proteins/2532" } ], "reference": [ { "type": "PubMed", "id": "30899004", "url": "https://glygen.org/publication/PubMed/30899004" } ] }, { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "30899004", "url": "https://glygen.org/publication/PubMed/30899004", "database": "PubMed", "categories": [ "Other" ] }, { "id": "2532", "url": "https://glyconnect.expasy.org/browser/proteins/2532", "database": "GlyConnect", "categories": [ "Glycomics", "Glycoproteomics" ] }, { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "Q8R4G0", "url": "https://www.uniprot.org/uniprotkb/Q8R4G0", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "NLHATSCLYDNSKLTCECEH", "down_seq": "TTGPDCGKCKKNYQGRPWSP", "glycosylation": [ { "glytoucan_ac": "G06110VR", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn320", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2532", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2532" } ] }, { "glytoucan_ac": "G39188ZX", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn320", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2532", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2532" } ] }, { "glytoucan_ac": "G41247ZX", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "LTCECEHNTTGPDCGK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn320", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "G80920RR", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "LTCECEHNTTGPDCGK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn320", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn320", "evidence": [ { "id": "Q8R4G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8R4G0#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "433", "end_pos": "433" } ] }, { "type": "snv", "site_list": [ { "start_pos": "433", "end_pos": "433" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 5 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 4 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 4 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 4 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 4 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8R4G0-1.352.352", "start_pos": 352, "end_pos": 352, "uniprot_canonical_ac": "Q8R4G0-1", "length": 539, "uniprot_id": "NTNG1_MOUSE", "protein_name": "Netrin-G1", "refseq_ac": "NP_001156820", "refseq_name": "netrin-G1 isoform b", "gene_name": "Ntng1", "gene_names_uniprotkb": "Ntng1; Kiaa0976; Lmnt1", "gene_names_refseq": "A930010C08Rik; Lmnt1; Ntng1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8R4G0", "url": "https://www.uniprot.org/uniprotkb/Q8R4G0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "NYQGRPWSPGSYLPIPKGTA", "down_seq": "TCIPSISSIGNCECFGHSNR", "glycosylation": [ { "glytoucan_ac": "G63276XU", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "GTANTSVPALDYLSNCECFGHSNR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn352", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "433", "end_pos": "433" } ] }, { "type": "snv", "site_list": [ { "start_pos": "433", "end_pos": "433" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8R4G0-1.406.406", "start_pos": 406, "end_pos": 406, "uniprot_canonical_ac": "Q8R4G0-1", "length": 539, "uniprot_id": "NTNG1_MOUSE", "protein_name": "Netrin-G1", "refseq_ac": "NP_001156820", "refseq_name": "netrin-G1 isoform b", "gene_name": "Ntng1", "gene_names_uniprotkb": "Ntng1; Kiaa0976; Lmnt1", "gene_names_refseq": "A930010C08Rik; Lmnt1; Ntng1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8R4G0", "url": "https://www.uniprot.org/uniprotkb/Q8R4G0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "Q8R4G0", "url": "https://www.uniprot.org/uniprotkb/Q8R4G0", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "SCKHNTRGQHCELCRLGYFR", "down_seq": "ASAQLDDENVCIECYCNPLG", "glycosylation": [ { "glytoucan_ac": "G14972EH", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "IWPNISSLEVSNPK", "relation": "attached", "comment": "reported site N374 is on non-canonical isoform F8WJ50-1 which maps to canonical isoform site Q8R4G0-1:406", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn406", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn406", "evidence": [ { "id": "Q8R4G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8R4G0#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "433", "end_pos": "433" } ] }, { "type": "snv", "site_list": [ { "start_pos": "433", "end_pos": "433" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8R4G0-1.433.433", "start_pos": 433, "end_pos": 433, "uniprot_canonical_ac": "Q8R4G0-1", "length": 539, "uniprot_id": "NTNG1_MOUSE", "protein_name": "Netrin-G1", "refseq_ac": "NP_001156820", "refseq_name": "netrin-G1 isoform b", "gene_name": "Ntng1", "gene_names_uniprotkb": "Ntng1; Kiaa0976; Lmnt1", "gene_names_refseq": "A930010C08Rik; Lmnt1; Ntng1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8R4G0", "url": "https://www.uniprot.org/uniprotkb/Q8R4G0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "Q8R4G0", "url": "https://www.uniprot.org/uniprotkb/Q8R4G0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "rs3388648835", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388648835", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "DENVCIECYCNPLGSIHDRC", "down_seq": "GSGFCECKTGTTGPKCDECL", "glycosylation": [ { "glytoucan_ac": "G14972EH", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "CNGSGFCECK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn433", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "G80920RR", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "CNGSGFCECK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn433", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn433", "evidence": [ { "id": "Q8R4G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8R4G0#ptm_processing" } ] } ], "snv": [ { "evidence": [ { "id": "rs3388648835", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388648835" } ], "glycoeffect": [ "n-glyco-sequon-loss" ], "sequence_org": "N", "sequence_mut": "T", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-loss (NGS->TGS).", "chr_id": "3", "chr_pos": "109735035", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "N433", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "433", "end_pos": "433" } ] }, { "type": "snv", "site_list": [ { "start_pos": "433", "end_pos": "433" } ] } ], "categories": [ "glycosylation_flag", "snv_flag" ], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 2 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 2 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 2 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 2 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q2TBE6-1.44.44", "start_pos": 44, "end_pos": 44, "uniprot_canonical_ac": "Q2TBE6-1", "length": 479, "uniprot_id": "P4K2A_MOUSE", "protein_name": "Phosphatidylinositol 4-kinase type 2-alpha", "refseq_ac": "NP_663476", "refseq_name": "phosphatidylinositol 4-kinase type 2-alpha", "gene_name": "Pi4k2a", "gene_names_uniprotkb": "Pi4k2a", "gene_names_refseq": "Pi4k2a; Pi4k2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q2TBE6", "url": "https://www.uniprot.org/uniprotkb/Q2TBE6" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q2TBE6", "url": "https://www.uniprot.org/uniprotkb/Q2TBE6", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SGAHFPQVPGGAVRVAAAAG", "down_seq": "GPSPPCSPGHDRERQPLLDR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q2TBE6", "url": "https://www.uniprot.org/uniprotkb/Q2TBE6" } ], "site_lbl": "Ser44" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "44", "end_pos": "44" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "Q2TBE6-1.47.47", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q2TBE6-1.51.51", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q2TBE6-1.462.462", "start_pos": 462, "end_pos": 462, "uniprot_canonical_ac": "Q2TBE6-1", "length": 479, "uniprot_id": "P4K2A_MOUSE", "protein_name": "Phosphatidylinositol 4-kinase type 2-alpha", "refseq_ac": "NP_663476", "refseq_name": "phosphatidylinositol 4-kinase type 2-alpha", "gene_name": "Pi4k2a", "gene_names_uniprotkb": "Pi4k2a", "gene_names_refseq": "Pi4k2a; Pi4k2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q2TBE6", "url": "https://www.uniprot.org/uniprotkb/Q2TBE6" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q2TBE6", "url": "https://www.uniprot.org/uniprotkb/Q2TBE6", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "HLVQMPPVIVETARSHQRSA", "down_seq": "ESYTQSFQSRKPFFSWW", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q2TBE6", "url": "https://www.uniprot.org/uniprotkb/Q2TBE6" } ], "site_lbl": "Ser462" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "44", "end_pos": "44" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q2TBE6-1.47.47", "start_pos": 47, "end_pos": 47, "uniprot_canonical_ac": "Q2TBE6-1", "length": 479, "uniprot_id": "P4K2A_MOUSE", "protein_name": "Phosphatidylinositol 4-kinase type 2-alpha", "refseq_ac": "NP_663476", "refseq_name": "phosphatidylinositol 4-kinase type 2-alpha", "gene_name": "Pi4k2a", "gene_names_uniprotkb": "Pi4k2a", "gene_names_refseq": "Pi4k2a; Pi4k2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q2TBE6", "url": "https://www.uniprot.org/uniprotkb/Q2TBE6" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q2TBE6", "url": "https://www.uniprot.org/uniprotkb/Q2TBE6" }, { "database": "iPTMnet", "id": "Q2TBE6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q2TBE6" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "title": "The phagosomal proteome in interferon-gamma-activated macrophages.", "journal": "Immunity", "date": "2009", "authors": "Trost M, English L, Lemieux S, Courcelles M, Desjardins M, Thibault P", "evidence": [ { "database": "UniProtKB", "id": "Q2TBE6", "url": "https://www.uniprot.org/uniprotkb/Q2TBE6" }, { "database": "iPTMnet", "id": "Q2TBE6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q2TBE6" } ], "reference": [ { "type": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" } ] }, { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q2TBE6", "url": "https://www.uniprot.org/uniprotkb/Q2TBE6" }, { "database": "iPTMnet", "id": "Q2TBE6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q2TBE6" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] } ], "crossref": [ { "id": "Q2TBE6", "url": "https://www.uniprot.org/uniprotkb/Q2TBE6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q2TBE6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q2TBE6", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "HFPQVPGGAVRVAAAAGSGP", "down_seq": "PPCSPGHDRERQPLLDRARG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q2TBE6", "url": "https://www.uniprot.org/uniprotkb/Q2TBE6" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" }, { "database": "iPTMnet", "id": "Q2TBE6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q2TBE6" } ], "site_lbl": "Ser47" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "44", "end_pos": "44" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "Q2TBE6-1.44.44", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q2TBE6-1.51.51", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q2TBE6-1.51.51", "start_pos": 51, "end_pos": 51, "uniprot_canonical_ac": "Q2TBE6-1", "length": 479, "uniprot_id": "P4K2A_MOUSE", "protein_name": "Phosphatidylinositol 4-kinase type 2-alpha", "refseq_ac": "NP_663476", "refseq_name": "phosphatidylinositol 4-kinase type 2-alpha", "gene_name": "Pi4k2a", "gene_names_uniprotkb": "Pi4k2a", "gene_names_refseq": "Pi4k2a; Pi4k2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q2TBE6", "url": "https://www.uniprot.org/uniprotkb/Q2TBE6" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "The phagosomal proteome in interferon-gamma-activated macrophages.", "journal": "Immunity", "date": "2009", "authors": "Trost M, English L, Lemieux S, Courcelles M, Desjardins M, Thibault P", "evidence": [ { "database": "UniProtKB", "id": "Q2TBE6", "url": "https://www.uniprot.org/uniprotkb/Q2TBE6" }, { "database": "iPTMnet", "id": "Q2TBE6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q2TBE6" } ], "reference": [ { "type": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" } ] }, { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q2TBE6", "url": "https://www.uniprot.org/uniprotkb/Q2TBE6" }, { "database": "iPTMnet", "id": "Q2TBE6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q2TBE6" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q2TBE6", "url": "https://www.uniprot.org/uniprotkb/Q2TBE6" }, { "database": "iPTMnet", "id": "Q2TBE6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q2TBE6" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] } ], "crossref": [ { "id": "Q2TBE6", "url": "https://www.uniprot.org/uniprotkb/Q2TBE6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q2TBE6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q2TBE6", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VPGGAVRVAAAAGSGPSPPC", "down_seq": "PGHDRERQPLLDRARGAAAQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q2TBE6", "url": "https://www.uniprot.org/uniprotkb/Q2TBE6" }, { "database": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" }, { "database": "iPTMnet", "id": "Q2TBE6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q2TBE6" } ], "site_lbl": "Ser51" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "44", "end_pos": "44" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "Q2TBE6-1.44.44", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q2TBE6-1.47.47", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q2TBE6-1.5.5", "start_pos": 5, "end_pos": 5, "uniprot_canonical_ac": "Q2TBE6-1", "length": 479, "uniprot_id": "P4K2A_MOUSE", "protein_name": "Phosphatidylinositol 4-kinase type 2-alpha", "refseq_ac": "NP_663476", "refseq_name": "phosphatidylinositol 4-kinase type 2-alpha", "gene_name": "Pi4k2a", "gene_names_uniprotkb": "Pi4k2a", "gene_names_refseq": "Pi4k2a; Pi4k2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q2TBE6", "url": "https://www.uniprot.org/uniprotkb/Q2TBE6" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q2TBE6", "url": "https://www.uniprot.org/uniprotkb/Q2TBE6", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MDET", "down_seq": "PLVSPERAQPPEYTFPSGSG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q2TBE6", "url": "https://www.uniprot.org/uniprotkb/Q2TBE6" } ], "site_lbl": "Ser5" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "44", "end_pos": "44" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "Q2TBE6-1.9.9", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q2TBE6-1.9.9", "start_pos": 9, "end_pos": 9, "uniprot_canonical_ac": "Q2TBE6-1", "length": 479, "uniprot_id": "P4K2A_MOUSE", "protein_name": "Phosphatidylinositol 4-kinase type 2-alpha", "refseq_ac": "NP_663476", "refseq_name": "phosphatidylinositol 4-kinase type 2-alpha", "gene_name": "Pi4k2a", "gene_names_uniprotkb": "Pi4k2a", "gene_names_refseq": "Pi4k2a; Pi4k2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q2TBE6", "url": "https://www.uniprot.org/uniprotkb/Q2TBE6" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q2TBE6", "url": "https://www.uniprot.org/uniprotkb/Q2TBE6", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MDETSPLV", "down_seq": "PERAQPPEYTFPSGSGAHFP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q2TBE6", "url": "https://www.uniprot.org/uniprotkb/Q2TBE6" } ], "site_lbl": "Ser9" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "44", "end_pos": "44" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "Q2TBE6-1.5.5", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8BIF2-1.159.159", "start_pos": 159, "end_pos": 159, "uniprot_canonical_ac": "Q8BIF2-1", "length": 374, "uniprot_id": "RFOX3_MOUSE", "protein_name": "RNA binding protein fox-1 homolog 3", "refseq_ac": "NP_001020102", "refseq_name": "RNA binding protein fox-1 homolog 3 isoform 3", "gene_name": "Rbfox3", "gene_names_uniprotkb": "Rbfox3; D11Bwg0517e; Hrnbp3", "gene_names_refseq": "Fox-3; Hrnbp3; NeuN; Neuna60; Rbfox3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BIF2", "url": "https://www.uniprot.org/uniprotkb/Q8BIF2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "rs3389224187", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389224187", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "GFGFVTFETSSDADRAREKL", "down_seq": "GTIVEGRKIEVNNATARVMT", "glycosylation": [ { "glytoucan_ac": "G80920RR", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "LNGTIVEGR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn159", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "snv": [ { "evidence": [ { "id": "rs3389224187", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389224187" } ], "glycoeffect": [ "n-glyco-sequon-loss" ], "sequence_org": "N", "sequence_mut": "Y", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-loss (NGT->YGT).", "chr_id": "11", "chr_pos": "118393700", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "N159", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "159", "end_pos": "159" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "354", "end_pos": "354" } ] }, { "type": "snv", "site_list": [ { "start_pos": "159", "end_pos": "159" } ] } ], "categories": [ "glycosylation_flag", "snv_flag" ], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "upstream", "id": "Q8BIF2-1.172.172", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BIF2-1.172.172", "start_pos": 172, "end_pos": 172, "uniprot_canonical_ac": "Q8BIF2-1", "length": 374, "uniprot_id": "RFOX3_MOUSE", "protein_name": "RNA binding protein fox-1 homolog 3", "refseq_ac": "NP_001020102", "refseq_name": "RNA binding protein fox-1 homolog 3 isoform 3", "gene_name": "Rbfox3", "gene_names_uniprotkb": "Rbfox3; D11Bwg0517e; Hrnbp3", "gene_names_refseq": "Fox-3; Hrnbp3; NeuN; Neuna60; Rbfox3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BIF2", "url": "https://www.uniprot.org/uniprotkb/Q8BIF2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "DRAREKLNGTIVEGRKIEVN", "down_seq": "ATARVMTNKKPGNPYANGWK", "glycosylation": [ { "glytoucan_ac": "G02815KT", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "KIEVNNATAR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn172", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "159", "end_pos": "159" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "354", "end_pos": "354" } ] }, { "type": "snv", "site_list": [ { "start_pos": "159", "end_pos": "159" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "Q8BIF2-1.159.159", "categories": [ "glycosylation_flag", "snv_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BIF2-1.215.215", "start_pos": 215, "end_pos": 215, "uniprot_canonical_ac": "Q8BIF2-1", "length": 374, "uniprot_id": "RFOX3_MOUSE", "protein_name": "RNA binding protein fox-1 homolog 3", "refseq_ac": "NP_001020102", "refseq_name": "RNA binding protein fox-1 homolog 3 isoform 3", "gene_name": "Rbfox3", "gene_names_uniprotkb": "Rbfox3; D11Bwg0517e; Hrnbp3", "gene_names_refseq": "Fox-3; Hrnbp3; NeuN; Neuna60; Rbfox3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BIF2", "url": "https://www.uniprot.org/uniprotkb/Q8BIF2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "PVVGTVYGPEFYAVTSFPYP", "down_seq": "TGTAVAYRGAHLRGRGRAVY", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr215", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "159", "end_pos": "159" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "354", "end_pos": "354" } ] }, { "type": "snv", "site_list": [ { "start_pos": "159", "end_pos": "159" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8BIF2-1.352.352", "start_pos": 352, "end_pos": 352, "uniprot_canonical_ac": "Q8BIF2-1", "length": 374, "uniprot_id": "RFOX3_MOUSE", "protein_name": "RNA binding protein fox-1 homolog 3", "refseq_ac": "NP_001020102", "refseq_name": "RNA binding protein fox-1 homolog 3 isoform 3", "gene_name": "Rbfox3", "gene_names_uniprotkb": "Rbfox3; D11Bwg0517e; Hrnbp3", "gene_names_refseq": "Fox-3; Hrnbp3; NeuN; Neuna60; Rbfox3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BIF2", "url": "https://www.uniprot.org/uniprotkb/Q8BIF2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "SDSYGRVYAAADPYHHTIGP", "down_seq": "ATYSIGTMASLCRGGYSRFT", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr352", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "159", "end_pos": "159" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "354", "end_pos": "354" } ] }, { "type": "snv", "site_list": [ { "start_pos": "159", "end_pos": "159" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "Q8BIF2-1.354.354", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8BIF2-1.354.354", "start_pos": 354, "end_pos": 354, "uniprot_canonical_ac": "Q8BIF2-1", "length": 374, "uniprot_id": "RFOX3_MOUSE", "protein_name": "RNA binding protein fox-1 homolog 3", "refseq_ac": "NP_001020102", "refseq_name": "RNA binding protein fox-1 homolog 3 isoform 3", "gene_name": "Rbfox3", "gene_names_uniprotkb": "Rbfox3; D11Bwg0517e; Hrnbp3", "gene_names_refseq": "Fox-3; Hrnbp3; NeuN; Neuna60; Rbfox3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BIF2", "url": "https://www.uniprot.org/uniprotkb/Q8BIF2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Novel Antibodies for the Simple and Efficient Enrichment of Native O-GlcNAc Modified Peptides.", "journal": "Molecular & cellular proteomics : MCP", "date": "2021", "authors": "Burt RA, Dejanovic B, Peckham HJ, Lee KA, Li X, Ounadjela JR, Rao A, Malaker SA, Carr SA, Myers SA", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8BIF2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BIF2" }, { "database": "O-GlcNAc Atlas", "id": "Q8BIF2", "url": "https://oglcnac.org/atlas/detail/Q8BIF2" } ], "reference": [ { "type": "PubMed", "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516" } ] } ], "crossref": [ { "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BIF2", "url": "https://oglcnac.org/atlas/detail/Q8BIF2", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "SYGRVYAAADPYHHTIGPTA", "down_seq": "YSIGTMASLCRGGYSRFTPY", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr354", "evidence": [ { "id": "34678516", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34678516" }, { "id": "Q8BIF2", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8BIF2" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "159", "end_pos": "159" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "354", "end_pos": "354" } ] }, { "type": "snv", "site_list": [ { "start_pos": "159", "end_pos": "159" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "Q8BIF2-1.352.352", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BIF2-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "Q8BIF2-1", "length": 374, "uniprot_id": "RFOX3_MOUSE", "protein_name": "RNA binding protein fox-1 homolog 3", "refseq_ac": "NP_001020102", "refseq_name": "RNA binding protein fox-1 homolog 3 isoform 3", "gene_name": "Rbfox3", "gene_names_uniprotkb": "Rbfox3; D11Bwg0517e; Hrnbp3", "gene_names_refseq": "Fox-3; Hrnbp3; NeuN; Neuna60; Rbfox3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BIF2", "url": "https://www.uniprot.org/uniprotkb/Q8BIF2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Novel Antibodies for the Simple and Efficient Enrichment of Native O-GlcNAc Modified Peptides.", "journal": "Molecular & cellular proteomics : MCP", "date": "2021", "authors": "Burt RA, Dejanovic B, Peckham HJ, Lee KA, Li X, Ounadjela JR, Rao A, Malaker SA, Carr SA, Myers SA", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8BIF2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BIF2" }, { "database": "O-GlcNAc Atlas", "id": "Q8BIF2", "url": "https://oglcnac.org/atlas/detail/Q8BIF2" } ], "reference": [ { "type": "PubMed", "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516" } ] } ], "crossref": [ { "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BIF2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BIF2", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "34678516", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34678516" }, { "id": "Q8BIF2", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BIF2" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "159", "end_pos": "159" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "354", "end_pos": "354" } ] }, { "type": "snv", "site_list": [ { "start_pos": "159", "end_pos": "159" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P97438-1.110.110", "start_pos": 110, "end_pos": 110, "uniprot_canonical_ac": "P97438-1", "length": 426, "uniprot_id": "KCNK2_MOUSE", "protein_name": "Potassium channel subfamily K member 2", "refseq_ac": "NP_001153322", "refseq_name": "potassium channel subfamily K member 2 isoform 1", "gene_name": "Kcnk2", "gene_names_uniprotkb": "Kcnk2", "gene_names_refseq": "A430027H14Rik; K2P2.1; Kcnk2; TREK-1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Mixing and matching TREK/TRAAK subunits generate heterodimeric K2P channels with unique properties.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2016-04-12", "authors": "Blin Sandy, Ben Soussia Ismail, Kim Eun-Jin, Brau Fr\u00e9d\u00e9ric, Kang Dawon, Lesage Florian, Bichet Delphine", "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" } ], "reference": [ { "type": "PubMed", "id": "27035965", "url": "https://glygen.org/publication/PubMed/27035965" } ] } ], "crossref": [ { "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "27035965", "url": "https://glygen.org/publication/PubMed/27035965", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "SQRTTIVIQKQTFIAQHACV", "down_seq": "STELDELIQQIVAAINAGII", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn110", "evidence": [ { "id": "P97438", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P97438#ptm_processing" } ] } ], "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "D", "comment": "Confers sensitivity to ruthenium red.", "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" }, { "database": "PubMed", "id": "27035965", "url": "https://glygen.org/publication/PubMed/27035965" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "110", "end_pos": "110" }, { "start_pos": "134", "end_pos": "134" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "126", "end_pos": "126" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "311", "end_pos": "311" }, { "start_pos": "333", "end_pos": "333" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "348", "end_pos": "348" } ] } ], "categories": [ "glycosylation_flag", "mutagenesis_flag" ], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P97438-1.91.91", "categories": [ "mutagenesis_flag" ] }, { "distance": 17, "direction": "downstream", "id": "P97438-1.93.93", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P97438-1.108.108", "categories": [ "mutagenesis_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P97438-1.126.126", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P97438-1.134.134", "start_pos": 134, "end_pos": 134, "uniprot_canonical_ac": "P97438-1", "length": 426, "uniprot_id": "KCNK2_MOUSE", "protein_name": "Potassium channel subfamily K member 2", "refseq_ac": "NP_001153322", "refseq_name": "potassium channel subfamily K member 2 isoform 1", "gene_name": "Kcnk2", "gene_names_uniprotkb": "Kcnk2", "gene_names_refseq": "A430027H14Rik; K2P2.1; Kcnk2; TREK-1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "LDELIQQIVAAINAGIIPLG", "down_seq": "SSNQVSHWDLGSSFFFAGTV", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn134", "evidence": [ { "id": "P97438", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P97438#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "110", "end_pos": "110" }, { "start_pos": "134", "end_pos": "134" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "126", "end_pos": "126" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "311", "end_pos": "311" }, { "start_pos": "333", "end_pos": "333" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "348", "end_pos": "348" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "P97438-1.126.126", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P97438-1.137.137", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P97438-1.108.108", "start_pos": 108, "end_pos": 108, "uniprot_canonical_ac": "P97438-1", "length": 426, "uniprot_id": "KCNK2_MOUSE", "protein_name": "Potassium channel subfamily K member 2", "refseq_ac": "NP_001153322", "refseq_name": "potassium channel subfamily K member 2 isoform 1", "gene_name": "Kcnk2", "gene_names_uniprotkb": "Kcnk2", "gene_names_refseq": "A430027H14Rik; K2P2.1; Kcnk2; TREK-1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A disulphide-linked heterodimer of TWIK-1 and TREK-1 mediates passive conductance in astrocytes.", "journal": "Nature communications", "date": "2014", "authors": "Hwang EM, Kim E, Yarishkin O, Woo DH, Han KS, Park N, Bae Y, Woo J, Kim D, Park M, Lee CJ, Park JY", "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" } ], "reference": [ { "type": "PubMed", "id": "24496152", "url": "https://glygen.org/publication/PubMed/24496152" } ] } ], "crossref": [ { "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "24496152", "url": "https://glygen.org/publication/PubMed/24496152", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "C", "start_aa": "C", "up_seq": "EISQRTTIVIQKQTFIAQHA", "down_seq": "VNSTELDELIQQIVAAINAG", "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Abolishes formation of a disulfide-linked heterodimer with KCNK1.", "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" }, { "database": "PubMed", "id": "24496152", "url": "https://glygen.org/publication/PubMed/24496152" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "110", "end_pos": "110" }, { "start_pos": "134", "end_pos": "134" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "126", "end_pos": "126" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "311", "end_pos": "311" }, { "start_pos": "333", "end_pos": "333" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "348", "end_pos": "348" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P97438-1.91.91", "categories": [ "mutagenesis_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P97438-1.93.93", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P97438-1.110.110", "categories": [ "glycosylation_flag", "mutagenesis_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P97438-1.126.126", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P97438-1.126.126", "start_pos": 126, "end_pos": 126, "uniprot_canonical_ac": "P97438-1", "length": 426, "uniprot_id": "KCNK2_MOUSE", "protein_name": "Potassium channel subfamily K member 2", "refseq_ac": "NP_001153322", "refseq_name": "potassium channel subfamily K member 2 isoform 1", "gene_name": "Kcnk2", "gene_names_uniprotkb": "Kcnk2", "gene_names_refseq": "A430027H14Rik; K2P2.1; Kcnk2; TREK-1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Heterodimerization within the TREK channel subfamily produces a diverse family of highly regulated potassium channels.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2016-04-12", "authors": "Levitz Joshua, Royal Perrine, Comoglio Yannick, Wdziekonski Brigitte, Schaub S\u00e9bastien, Clemens Daniel M, Isacoff Ehud Y, Sandoz Guillaume", "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" } ], "reference": [ { "type": "PubMed", "id": "27035963", "url": "https://glygen.org/publication/PubMed/27035963" } ] }, { "title": "Extracellular acidification exerts opposite actions on TREK1 and TREK2 potassium channels via a single conserved histidine residue.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2009-08-25", "authors": "Sandoz Guillaume, Douguet Dominique, Chatelain Franck, Lazdunski Michel, Lesage Florian", "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" } ], "reference": [ { "type": "PubMed", "id": "19667202", "url": "https://glygen.org/publication/PubMed/19667202" } ] } ], "crossref": [ { "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "27035963", "url": "https://glygen.org/publication/PubMed/27035963", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19667202", "url": "https://glygen.org/publication/PubMed/19667202", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "HACVNSTELDELIQQIVAAI", "down_seq": "AGIIPLGNSSNQVSHWDLGS", "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "A", "comment": "In homodimer, displays increased basal current. In heterodimer with KCNK10, displays increased basal current and KCNK10-like pH-dependence.", "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" }, { "database": "PubMed", "id": "27035963", "url": "https://glygen.org/publication/PubMed/27035963" }, { "database": "PubMed", "id": "19667202", "url": "https://glygen.org/publication/PubMed/19667202" } ] }, { "sequence_org": "N", "sequence_mut": "K", "comment": "In homodimer, displays decreased basal current. In heterodimer with KCNK10, displays decreased basal current and KCNK10-like pH-dependence.", "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" }, { "database": "PubMed", "id": "27035963", "url": "https://glygen.org/publication/PubMed/27035963" }, { "database": "PubMed", "id": "19667202", "url": "https://glygen.org/publication/PubMed/19667202" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "110", "end_pos": "110" }, { "start_pos": "134", "end_pos": "134" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "126", "end_pos": "126" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "311", "end_pos": "311" }, { "start_pos": "333", "end_pos": "333" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "348", "end_pos": "348" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P97438-1.108.108", "categories": [ "mutagenesis_flag" ] }, { "distance": 16, "direction": "downstream", "id": "P97438-1.110.110", "categories": [ "glycosylation_flag", "mutagenesis_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P97438-1.134.134", "categories": [ "glycosylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P97438-1.137.137", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P97438-1.137.137", "start_pos": 137, "end_pos": 137, "uniprot_canonical_ac": "P97438-1", "length": 426, "uniprot_id": "KCNK2_MOUSE", "protein_name": "Potassium channel subfamily K member 2", "refseq_ac": "NP_001153322", "refseq_name": "potassium channel subfamily K member 2 isoform 1", "gene_name": "Kcnk2", "gene_names_uniprotkb": "Kcnk2", "gene_names_refseq": "A430027H14Rik; K2P2.1; Kcnk2; TREK-1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "K2P2.1 (TREK-1)-activator complexes reveal a cryptic selectivity filter binding site.", "journal": "Nature", "date": "2017", "authors": "Lolicato M, Arrigoni C, Mori T, Sekioka Y, Bryant C, Clark KA, Minor DL Jr", "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" } ], "reference": [ { "type": "PubMed", "id": "28693035", "url": "https://glygen.org/publication/PubMed/28693035" } ] } ], "crossref": [ { "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "28693035", "url": "https://glygen.org/publication/PubMed/28693035", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "LIQQIVAAINAGIIPLGNSS", "down_seq": "QVSHWDLGSSFFFAGTVITT", "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "I", "comment": "Results in voltage-independent channel gating.", "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" }, { "database": "PubMed", "id": "28693035", "url": "https://glygen.org/publication/PubMed/28693035" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "110", "end_pos": "110" }, { "start_pos": "134", "end_pos": "134" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "126", "end_pos": "126" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "311", "end_pos": "311" }, { "start_pos": "333", "end_pos": "333" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "348", "end_pos": "348" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "P97438-1.126.126", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P97438-1.134.134", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P97438-1.232.232", "start_pos": 232, "end_pos": 232, "uniprot_canonical_ac": "P97438-1", "length": 426, "uniprot_id": "KCNK2_MOUSE", "protein_name": "Potassium channel subfamily K member 2", "refseq_ac": "NP_001153322", "refseq_name": "potassium channel subfamily K member 2 isoform 1", "gene_name": "Kcnk2", "gene_names_uniprotkb": "Kcnk2", "gene_names_refseq": "A430027H14Rik; K2P2.1; Kcnk2; TREK-1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Extracellular acidification exerts opposite actions on TREK1 and TREK2 potassium channels via a single conserved histidine residue.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2009-08-25", "authors": "Sandoz Guillaume, Douguet Dominique, Chatelain Franck, Lazdunski Michel, Lesage Florian", "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" } ], "reference": [ { "type": "PubMed", "id": "19667202", "url": "https://glygen.org/publication/PubMed/19667202" } ] } ], "crossref": [ { "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19667202", "url": "https://glygen.org/publication/PubMed/19667202", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "F", "start_aa": "F", "up_seq": "IKWNVSQTKIRIISTIIFIL", "down_seq": "GCVLFVALPAVIFKHIEGWS", "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "A", "comment": "No effect on pH-dependence.", "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" }, { "database": "PubMed", "id": "19667202", "url": "https://glygen.org/publication/PubMed/19667202" } ] }, { "sequence_org": "F", "sequence_mut": "K", "comment": "No effect on pH-dependence.", "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" }, { "database": "PubMed", "id": "19667202", "url": "https://glygen.org/publication/PubMed/19667202" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "110", "end_pos": "110" }, { "start_pos": "134", "end_pos": "134" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "126", "end_pos": "126" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "311", "end_pos": "311" }, { "start_pos": "333", "end_pos": "333" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "348", "end_pos": "348" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P97438-1.271.271", "start_pos": 271, "end_pos": 271, "uniprot_canonical_ac": "P97438-1", "length": 426, "uniprot_id": "KCNK2_MOUSE", "protein_name": "Potassium channel subfamily K member 2", "refseq_ac": "NP_001153322", "refseq_name": "potassium channel subfamily K member 2 isoform 1", "gene_name": "Kcnk2", "gene_names_uniprotkb": "Kcnk2", "gene_names_refseq": "A430027H14Rik; K2P2.1; Kcnk2; TREK-1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "K2P2.1 (TREK-1)-activator complexes reveal a cryptic selectivity filter binding site.", "journal": "Nature", "date": "2017", "authors": "Lolicato M, Arrigoni C, Mori T, Sekioka Y, Bryant C, Clark KA, Minor DL Jr", "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" } ], "reference": [ { "type": "PubMed", "id": "28693035", "url": "https://glygen.org/publication/PubMed/28693035" } ] } ], "crossref": [ { "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "28693035", "url": "https://glygen.org/publication/PubMed/28693035", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "WSALDAIYFVVITLTTIGFG", "down_seq": "YVAGGSDIEYLDFYKPVVWF", "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "Q", "comment": "Loss of a cryptic cation-pi interaction that activates channel gating.", "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" }, { "database": "PubMed", "id": "28693035", "url": "https://glygen.org/publication/PubMed/28693035" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "110", "end_pos": "110" }, { "start_pos": "134", "end_pos": "134" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "126", "end_pos": "126" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "311", "end_pos": "311" }, { "start_pos": "333", "end_pos": "333" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "348", "end_pos": "348" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P97438-1.297.297", "start_pos": 297, "end_pos": 297, "uniprot_canonical_ac": "P97438-1", "length": 426, "uniprot_id": "KCNK2_MOUSE", "protein_name": "Potassium channel subfamily K member 2", "refseq_ac": "NP_001153322", "refseq_name": "potassium channel subfamily K member 2 isoform 1", "gene_name": "Kcnk2", "gene_names_uniprotkb": "Kcnk2", "gene_names_refseq": "A430027H14Rik; K2P2.1; Kcnk2; TREK-1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "AKAP150, a switch to convert mechano-, pH- and arachidonic acid-sensitive TREK K(+) channels into open leak channels.", "journal": "The EMBO journal", "date": "2006", "authors": "Sandoz G, Thummler S, Duprat F, Feliciangeli S, Vinh J, Escoubas P, Guy N, Lazdunski M, Lesage F", "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" } ], "reference": [ { "type": "PubMed", "id": "17110924", "url": "https://glygen.org/publication/PubMed/17110924" } ] } ], "crossref": [ { "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17110924", "url": "https://glygen.org/publication/PubMed/17110924", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "L", "start_aa": "L", "up_seq": "SDIEYLDFYKPVVWFWILVG", "down_seq": "AYFAAVLSMIGDWLRVISKK", "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "A", "comment": "Disrupts colocalization with AKAP5 at the plasma membrane; when associated with A-301; A302; A-304 and A-311.", "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" }, { "database": "PubMed", "id": "17110924", "url": "https://glygen.org/publication/PubMed/17110924" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "110", "end_pos": "110" }, { "start_pos": "134", "end_pos": "134" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "126", "end_pos": "126" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "311", "end_pos": "311" }, { "start_pos": "333", "end_pos": "333" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "348", "end_pos": "348" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "P97438-1.301.301", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P97438-1.302.302", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P97438-1.304.304", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P97438-1.306.306", "categories": [ "mutagenesis_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P97438-1.311.311", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P97438-1.301.301", "start_pos": 301, "end_pos": 301, "uniprot_canonical_ac": "P97438-1", "length": 426, "uniprot_id": "KCNK2_MOUSE", "protein_name": "Potassium channel subfamily K member 2", "refseq_ac": "NP_001153322", "refseq_name": "potassium channel subfamily K member 2 isoform 1", "gene_name": "Kcnk2", "gene_names_uniprotkb": "Kcnk2", "gene_names_refseq": "A430027H14Rik; K2P2.1; Kcnk2; TREK-1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "AKAP150, a switch to convert mechano-, pH- and arachidonic acid-sensitive TREK K(+) channels into open leak channels.", "journal": "The EMBO journal", "date": "2006", "authors": "Sandoz G, Thummler S, Duprat F, Feliciangeli S, Vinh J, Escoubas P, Guy N, Lazdunski M, Lesage F", "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" } ], "reference": [ { "type": "PubMed", "id": "17110924", "url": "https://glygen.org/publication/PubMed/17110924" } ] } ], "crossref": [ { "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17110924", "url": "https://glygen.org/publication/PubMed/17110924", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "A", "start_aa": "A", "up_seq": "YLDFYKPVVWFWILVGLAYF", "down_seq": "AVLSMIGDWLRVISKKTKEE", "mutagenesis": [ { "sequence_org": "A", "sequence_mut": "A", "comment": "Disrupts colocalization with AKAP5 at the plasma membrane; when associated with A-297; A302; A-304 and A-311.", "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" }, { "database": "PubMed", "id": "17110924", "url": "https://glygen.org/publication/PubMed/17110924" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "110", "end_pos": "110" }, { "start_pos": "134", "end_pos": "134" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "126", "end_pos": "126" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "311", "end_pos": "311" }, { "start_pos": "333", "end_pos": "333" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "348", "end_pos": "348" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "P97438-1.297.297", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P97438-1.302.302", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P97438-1.304.304", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P97438-1.306.306", "categories": [ "mutagenesis_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P97438-1.311.311", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P97438-1.302.302", "start_pos": 302, "end_pos": 302, "uniprot_canonical_ac": "P97438-1", "length": 426, "uniprot_id": "KCNK2_MOUSE", "protein_name": "Potassium channel subfamily K member 2", "refseq_ac": "NP_001153322", "refseq_name": "potassium channel subfamily K member 2 isoform 1", "gene_name": "Kcnk2", "gene_names_uniprotkb": "Kcnk2", "gene_names_refseq": "A430027H14Rik; K2P2.1; Kcnk2; TREK-1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "AKAP150, a switch to convert mechano-, pH- and arachidonic acid-sensitive TREK K(+) channels into open leak channels.", "journal": "The EMBO journal", "date": "2006", "authors": "Sandoz G, Thummler S, Duprat F, Feliciangeli S, Vinh J, Escoubas P, Guy N, Lazdunski M, Lesage F", "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" } ], "reference": [ { "type": "PubMed", "id": "17110924", "url": "https://glygen.org/publication/PubMed/17110924" } ] } ], "crossref": [ { "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17110924", "url": "https://glygen.org/publication/PubMed/17110924", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "A", "start_aa": "A", "up_seq": "LDFYKPVVWFWILVGLAYFA", "down_seq": "VLSMIGDWLRVISKKTKEEV", "mutagenesis": [ { "sequence_org": "A", "sequence_mut": "A", "comment": "Disrupts colocalization with AKAP5 at the plasma membrane; when associated with A-297; A-301; A-304 and A-311.", "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" }, { "database": "PubMed", "id": "17110924", "url": "https://glygen.org/publication/PubMed/17110924" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "110", "end_pos": "110" }, { "start_pos": "134", "end_pos": "134" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "126", "end_pos": "126" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "311", "end_pos": "311" }, { "start_pos": "333", "end_pos": "333" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "348", "end_pos": "348" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "P97438-1.297.297", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P97438-1.301.301", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P97438-1.304.304", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P97438-1.306.306", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P97438-1.311.311", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P97438-1.304.304", "start_pos": 304, "end_pos": 304, "uniprot_canonical_ac": "P97438-1", "length": 426, "uniprot_id": "KCNK2_MOUSE", "protein_name": "Potassium channel subfamily K member 2", "refseq_ac": "NP_001153322", "refseq_name": "potassium channel subfamily K member 2 isoform 1", "gene_name": "Kcnk2", "gene_names_uniprotkb": "Kcnk2", "gene_names_refseq": "A430027H14Rik; K2P2.1; Kcnk2; TREK-1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "AKAP150, a switch to convert mechano-, pH- and arachidonic acid-sensitive TREK K(+) channels into open leak channels.", "journal": "The EMBO journal", "date": "2006", "authors": "Sandoz G, Thummler S, Duprat F, Feliciangeli S, Vinh J, Escoubas P, Guy N, Lazdunski M, Lesage F", "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" } ], "reference": [ { "type": "PubMed", "id": "17110924", "url": "https://glygen.org/publication/PubMed/17110924" } ] } ], "crossref": [ { "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17110924", "url": "https://glygen.org/publication/PubMed/17110924", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "L", "start_aa": "L", "up_seq": "FYKPVVWFWILVGLAYFAAV", "down_seq": "SMIGDWLRVISKKTKEEVGE", "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "A", "comment": "Disrupts colocalization with AKAP5 at the plasma membrane; when associated with A-297; A-301; A302 and A-311.", "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" }, { "database": "PubMed", "id": "17110924", "url": "https://glygen.org/publication/PubMed/17110924" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "110", "end_pos": "110" }, { "start_pos": "134", "end_pos": "134" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "126", "end_pos": "126" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "311", "end_pos": "311" }, { "start_pos": "333", "end_pos": "333" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "348", "end_pos": "348" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "P97438-1.297.297", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P97438-1.301.301", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P97438-1.302.302", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P97438-1.306.306", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P97438-1.311.311", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P97438-1.306.306", "start_pos": 306, "end_pos": 306, "uniprot_canonical_ac": "P97438-1", "length": 426, "uniprot_id": "KCNK2_MOUSE", "protein_name": "Potassium channel subfamily K member 2", "refseq_ac": "NP_001153322", "refseq_name": "potassium channel subfamily K member 2 isoform 1", "gene_name": "Kcnk2", "gene_names_uniprotkb": "Kcnk2", "gene_names_refseq": "A430027H14Rik; K2P2.1; Kcnk2; TREK-1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Extracellular acidification exerts opposite actions on TREK1 and TREK2 potassium channels via a single conserved histidine residue.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2009-08-25", "authors": "Sandoz Guillaume, Douguet Dominique, Chatelain Franck, Lazdunski Michel, Lesage Florian", "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" } ], "reference": [ { "type": "PubMed", "id": "19667202", "url": "https://glygen.org/publication/PubMed/19667202" } ] } ], "crossref": [ { "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19667202", "url": "https://glygen.org/publication/PubMed/19667202", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "M", "start_aa": "M", "up_seq": "KPVVWFWILVGLAYFAAVLS", "down_seq": "IGDWLRVISKKTKEEVGEFR", "mutagenesis": [ { "sequence_org": "M", "sequence_mut": "A", "comment": "No effect on pH-dependence.", "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" }, { "database": "PubMed", "id": "19667202", "url": "https://glygen.org/publication/PubMed/19667202" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "110", "end_pos": "110" }, { "start_pos": "134", "end_pos": "134" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "126", "end_pos": "126" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "311", "end_pos": "311" }, { "start_pos": "333", "end_pos": "333" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "348", "end_pos": "348" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "P97438-1.297.297", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P97438-1.301.301", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P97438-1.302.302", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P97438-1.304.304", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P97438-1.311.311", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P97438-1.311.311", "start_pos": 311, "end_pos": 311, "uniprot_canonical_ac": "P97438-1", "length": 426, "uniprot_id": "KCNK2_MOUSE", "protein_name": "Potassium channel subfamily K member 2", "refseq_ac": "NP_001153322", "refseq_name": "potassium channel subfamily K member 2 isoform 1", "gene_name": "Kcnk2", "gene_names_uniprotkb": "Kcnk2", "gene_names_refseq": "A430027H14Rik; K2P2.1; Kcnk2; TREK-1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "AKAP150, a switch to convert mechano-, pH- and arachidonic acid-sensitive TREK K(+) channels into open leak channels.", "journal": "The EMBO journal", "date": "2006", "authors": "Sandoz G, Thummler S, Duprat F, Feliciangeli S, Vinh J, Escoubas P, Guy N, Lazdunski M, Lesage F", "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" } ], "reference": [ { "type": "PubMed", "id": "17110924", "url": "https://glygen.org/publication/PubMed/17110924" } ] } ], "crossref": [ { "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17110924", "url": "https://glygen.org/publication/PubMed/17110924", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "L", "start_aa": "L", "up_seq": "FWILVGLAYFAAVLSMIGDW", "down_seq": "RVISKKTKEEVGEFRAHAAE", "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "A", "comment": "Disrupts colocalization with AKAP5 at the plasma membrane; when associated with A-297; A-301; A302 and A-304.", "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" }, { "database": "PubMed", "id": "17110924", "url": "https://glygen.org/publication/PubMed/17110924" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "110", "end_pos": "110" }, { "start_pos": "134", "end_pos": "134" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "126", "end_pos": "126" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "311", "end_pos": "311" }, { "start_pos": "333", "end_pos": "333" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "348", "end_pos": "348" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "P97438-1.297.297", "categories": [ "mutagenesis_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P97438-1.301.301", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P97438-1.302.302", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P97438-1.304.304", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P97438-1.306.306", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P97438-1.333.333", "start_pos": 333, "end_pos": 333, "uniprot_canonical_ac": "P97438-1", "length": 426, "uniprot_id": "KCNK2_MOUSE", "protein_name": "Potassium channel subfamily K member 2", "refseq_ac": "NP_001153322", "refseq_name": "potassium channel subfamily K member 2 isoform 1", "gene_name": "Kcnk2", "gene_names_uniprotkb": "Kcnk2", "gene_names_refseq": "A430027H14Rik; K2P2.1; Kcnk2; TREK-1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Optical control of endogenous proteins with a photoswitchable conditional subunit reveals a role for TREK1 in GABA(B) signaling.", "journal": "Neuron", "date": "2012-06-21", "authors": "Sandoz Guillaume, Levitz Joshua, Kramer Richard H, Isacoff Ehud Y", "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" } ], "reference": [ { "type": "PubMed", "id": "22726831", "url": "https://glygen.org/publication/PubMed/22726831" } ] } ], "crossref": [ { "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "22726831", "url": "https://glygen.org/publication/PubMed/22726831", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "VISKKTKEEVGEFRAHAAEW", "down_seq": "ANVTAEFKETRRRLSVEIYD", "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "D", "comment": "Mimics the phosphorylated state and reduces the enhancement of current by activation via Gi-coupled GPCRs.", "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" }, { "database": "PubMed", "id": "22726831", "url": "https://glygen.org/publication/PubMed/22726831" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "110", "end_pos": "110" }, { "start_pos": "134", "end_pos": "134" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "126", "end_pos": "126" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "311", "end_pos": "311" }, { "start_pos": "333", "end_pos": "333" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "348", "end_pos": "348" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "upstream", "id": "P97438-1.348.348", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P97438-1.91.91", "start_pos": 91, "end_pos": 91, "uniprot_canonical_ac": "P97438-1", "length": 426, "uniprot_id": "KCNK2_MOUSE", "protein_name": "Potassium channel subfamily K member 2", "refseq_ac": "NP_001153322", "refseq_name": "potassium channel subfamily K member 2 isoform 1", "gene_name": "Kcnk2", "gene_names_uniprotkb": "Kcnk2", "gene_names_refseq": "A430027H14Rik; K2P2.1; Kcnk2; TREK-1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Extracellular acidification exerts opposite actions on TREK1 and TREK2 potassium channels via a single conserved histidine residue.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2009-08-25", "authors": "Sandoz Guillaume, Douguet Dominique, Chatelain Franck, Lazdunski Michel, Lesage Florian", "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" } ], "reference": [ { "type": "PubMed", "id": "19667202", "url": "https://glygen.org/publication/PubMed/19667202" } ] } ], "crossref": [ { "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19667202", "url": "https://glygen.org/publication/PubMed/19667202", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Q", "start_aa": "Q", "up_seq": "LYLIIGATVFKALEQPQEIS", "down_seq": "RTTIVIQKQTFIAQHACVNS", "mutagenesis": [ { "sequence_org": "Q", "sequence_mut": "A", "comment": "No effect on pH-dependence.", "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" }, { "database": "PubMed", "id": "19667202", "url": "https://glygen.org/publication/PubMed/19667202" } ] }, { "sequence_org": "Q", "sequence_mut": "K", "comment": "No effect on pH-dependence.", "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" }, { "database": "PubMed", "id": "19667202", "url": "https://glygen.org/publication/PubMed/19667202" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "110", "end_pos": "110" }, { "start_pos": "134", "end_pos": "134" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "126", "end_pos": "126" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "311", "end_pos": "311" }, { "start_pos": "333", "end_pos": "333" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "348", "end_pos": "348" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P97438-1.93.93", "categories": [ "mutagenesis_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P97438-1.108.108", "categories": [ "mutagenesis_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P97438-1.110.110", "categories": [ "glycosylation_flag", "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P97438-1.93.93", "start_pos": 93, "end_pos": 93, "uniprot_canonical_ac": "P97438-1", "length": 426, "uniprot_id": "KCNK2_MOUSE", "protein_name": "Potassium channel subfamily K member 2", "refseq_ac": "NP_001153322", "refseq_name": "potassium channel subfamily K member 2 isoform 1", "gene_name": "Kcnk2", "gene_names_uniprotkb": "Kcnk2", "gene_names_refseq": "A430027H14Rik; K2P2.1; Kcnk2; TREK-1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Extracellular acidification exerts opposite actions on TREK1 and TREK2 potassium channels via a single conserved histidine residue.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2009-08-25", "authors": "Sandoz Guillaume, Douguet Dominique, Chatelain Franck, Lazdunski Michel, Lesage Florian", "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" } ], "reference": [ { "type": "PubMed", "id": "19667202", "url": "https://glygen.org/publication/PubMed/19667202" } ] } ], "crossref": [ { "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19667202", "url": "https://glygen.org/publication/PubMed/19667202", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "LIIGATVFKALEQPQEISQR", "down_seq": "TIVIQKQTFIAQHACVNSTE", "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "No effect on pH-dependence.", "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" }, { "database": "PubMed", "id": "19667202", "url": "https://glygen.org/publication/PubMed/19667202" } ] }, { "sequence_org": "T", "sequence_mut": "D", "comment": "No effect on pH-dependence.", "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" }, { "database": "PubMed", "id": "19667202", "url": "https://glygen.org/publication/PubMed/19667202" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "110", "end_pos": "110" }, { "start_pos": "134", "end_pos": "134" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "126", "end_pos": "126" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "311", "end_pos": "311" }, { "start_pos": "333", "end_pos": "333" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "348", "end_pos": "348" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P97438-1.91.91", "categories": [ "mutagenesis_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P97438-1.108.108", "categories": [ "mutagenesis_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P97438-1.110.110", "categories": [ "glycosylation_flag", "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P97438-1.348.348", "start_pos": 348, "end_pos": 348, "uniprot_canonical_ac": "P97438-1", "length": 426, "uniprot_id": "KCNK2_MOUSE", "protein_name": "Potassium channel subfamily K member 2", "refseq_ac": "NP_001153322", "refseq_name": "potassium channel subfamily K member 2 isoform 1", "gene_name": "Kcnk2", "gene_names_uniprotkb": "Kcnk2", "gene_names_refseq": "A430027H14Rik; K2P2.1; Kcnk2; TREK-1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" }, { "database": "iPTMnet", "id": "P97438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P97438" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P97438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P97438", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "HAAEWTANVTAEFKETRRRL", "down_seq": "VEIYDKFQRATSVKRKLSAE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P97438", "url": "https://www.uniprot.org/uniprotkb/P97438" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "P97438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P97438" } ], "site_lbl": "Ser348" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "110", "end_pos": "110" }, { "start_pos": "134", "end_pos": "134" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "126", "end_pos": "126" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "311", "end_pos": "311" }, { "start_pos": "333", "end_pos": "333" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "348", "end_pos": "348" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P97438-1.333.333", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9QUG9-1.116.116", "start_pos": 116, "end_pos": 116, "uniprot_canonical_ac": "Q9QUG9-1", "length": 608, "uniprot_id": "GRP2_MOUSE", "protein_name": "RAS guanyl-releasing protein 2", "refseq_ac": "NP_035372", "refseq_name": "RAS guanyl-releasing protein 2 isoform 1", "gene_name": "Rasgrp2", "gene_names_uniprotkb": "Rasgrp2", "gene_names_refseq": "CDC25L; CalDAG-GEFI; Caldaggef1; Rasgrp2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9QUG9", "url": "https://www.uniprot.org/uniprotkb/Q9QUG9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9QUG9", "url": "https://www.uniprot.org/uniprotkb/Q9QUG9" }, { "database": "iPTMnet", "id": "Q9QUG9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9QUG9" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9QUG9", "url": "https://www.uniprot.org/uniprotkb/Q9QUG9" }, { "database": "iPTMnet", "id": "Q9QUG9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9QUG9" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] }, { "title": "DARPP-32/protein phosphatase 1 regulates Rasgrp2 as a novel component of dopamine D1 receptor signaling in striatum.", "journal": "Neurochemistry international", "date": "2022-11-06", "authors": "Kuroiwa Mahomi, Shuto Takahide, Nagai Taku, Amano Mutsuki, Kaibuchi Kozo, Nairn Angus C, Nishi Akinori", "evidence": [ { "database": "iPTMnet", "id": "Q9QUG9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9QUG9" } ], "reference": [ { "type": "PubMed", "id": "36351540", "url": "https://glygen.org/publication/PubMed/36351540" } ] } ], "crossref": [ { "id": "Q9QUG9", "url": "https://www.uniprot.org/uniprotkb/Q9QUG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9QUG9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9QUG9", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "36351540", "url": "https://glygen.org/publication/PubMed/36351540", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LAEQIKELKALLDQEGNRRH", "down_seq": "SLIDIESVPTYKWKRQVTQR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9QUG9", "url": "https://www.uniprot.org/uniprotkb/Q9QUG9" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" }, { "database": "iPTMnet", "id": "Q9QUG9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9QUG9" }, { "database": "PubMed", "id": "36351540", "url": "https://glygen.org/publication/PubMed/36351540" } ], "site_lbl": "Ser116" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "147", "end_pos": "147" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "586", "end_pos": "586" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "Q9QUG9-1.117.117", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9QUG9-1.117.117", "start_pos": 117, "end_pos": 117, "uniprot_canonical_ac": "Q9QUG9-1", "length": 608, "uniprot_id": "GRP2_MOUSE", "protein_name": "RAS guanyl-releasing protein 2", "refseq_ac": "NP_035372", "refseq_name": "RAS guanyl-releasing protein 2 isoform 1", "gene_name": "Rasgrp2", "gene_names_uniprotkb": "Rasgrp2", "gene_names_refseq": "CDC25L; CalDAG-GEFI; Caldaggef1; Rasgrp2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9QUG9", "url": "https://www.uniprot.org/uniprotkb/Q9QUG9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9QUG9", "url": "https://www.uniprot.org/uniprotkb/Q9QUG9" }, { "database": "iPTMnet", "id": "Q9QUG9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9QUG9" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] }, { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9QUG9", "url": "https://www.uniprot.org/uniprotkb/Q9QUG9" }, { "database": "iPTMnet", "id": "Q9QUG9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9QUG9" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "title": "DARPP-32/protein phosphatase 1 regulates Rasgrp2 as a novel component of dopamine D1 receptor signaling in striatum.", "journal": "Neurochemistry international", "date": "2022-11-06", "authors": "Kuroiwa Mahomi, Shuto Takahide, Nagai Taku, Amano Mutsuki, Kaibuchi Kozo, Nairn Angus C, Nishi Akinori", "evidence": [ { "database": "iPTMnet", "id": "Q9QUG9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9QUG9" } ], "reference": [ { "type": "PubMed", "id": "36351540", "url": "https://glygen.org/publication/PubMed/36351540" } ] } ], "crossref": [ { "id": "Q9QUG9", "url": "https://www.uniprot.org/uniprotkb/Q9QUG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9QUG9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9QUG9", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "36351540", "url": "https://glygen.org/publication/PubMed/36351540", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AEQIKELKALLDQEGNRRHS", "down_seq": "LIDIESVPTYKWKRQVTQRN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9QUG9", "url": "https://www.uniprot.org/uniprotkb/Q9QUG9" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q9QUG9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9QUG9" }, { "database": "PubMed", "id": "36351540", "url": "https://glygen.org/publication/PubMed/36351540" } ], "site_lbl": "Ser117" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "147", "end_pos": "147" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "586", "end_pos": "586" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "Q9QUG9-1.116.116", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9QUG9-1.147.147", "start_pos": 147, "end_pos": 147, "uniprot_canonical_ac": "Q9QUG9-1", "length": 608, "uniprot_id": "GRP2_MOUSE", "protein_name": "RAS guanyl-releasing protein 2", "refseq_ac": "NP_035372", "refseq_name": "RAS guanyl-releasing protein 2 isoform 1", "gene_name": "Rasgrp2", "gene_names_uniprotkb": "Rasgrp2", "gene_names_refseq": "CDC25L; CalDAG-GEFI; Caldaggef1; Rasgrp2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9QUG9", "url": "https://www.uniprot.org/uniprotkb/Q9QUG9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9QUG9", "url": "https://www.uniprot.org/uniprotkb/Q9QUG9" }, { "database": "iPTMnet", "id": "Q9QUG9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9QUG9" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q9QUG9", "url": "https://www.uniprot.org/uniprotkb/Q9QUG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9QUG9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9QUG9", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "YKWKRQVTQRNPVEQKKRKM", "down_seq": "LLFDHLEPMELAEHLTYLEY", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9QUG9", "url": "https://www.uniprot.org/uniprotkb/Q9QUG9" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q9QUG9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9QUG9" } ], "site_lbl": "Ser147" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "147", "end_pos": "147" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "586", "end_pos": "586" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9QUG9-1.523.523", "start_pos": 523, "end_pos": 523, "uniprot_canonical_ac": "Q9QUG9-1", "length": 608, "uniprot_id": "GRP2_MOUSE", "protein_name": "RAS guanyl-releasing protein 2", "refseq_ac": "NP_035372", "refseq_name": "RAS guanyl-releasing protein 2 isoform 1", "gene_name": "Rasgrp2", "gene_names_uniprotkb": "Rasgrp2", "gene_names_refseq": "CDC25L; CalDAG-GEFI; Caldaggef1; Rasgrp2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9QUG9", "url": "https://www.uniprot.org/uniprotkb/Q9QUG9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "The Guanine-Nucleotide Exchange Factor Caldag Gefi Fine-Tunes Functional Properties of Regulatory T Cells.", "journal": "European journal of microbiology & immunology", "date": "2017-06", "authors": "Niemz Jana, Kliche Stefanie, Pils Marina C, Morrison Eliot, Manns Annika, Freund Christian, Crittenden Jill R, Graybiel Ann M, Galla Melanie, J\u00e4nsch Lothar, Huehn Jochen", "evidence": [ { "database": "iPTMnet", "id": "Q9QUG9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9QUG9" } ], "reference": [ { "type": "PubMed", "id": "28690878", "url": "https://glygen.org/publication/PubMed/28690878" } ] } ], "crossref": [ { "id": "Q9QUG9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9QUG9", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "28690878", "url": "https://glygen.org/publication/PubMed/28690878", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "ESNSLRPVACRHCKALILGI", "down_seq": "KQGLKCRACGVNCHKQCKER", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q9QUG9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9QUG9" }, { "database": "PubMed", "id": "28690878", "url": "https://glygen.org/publication/PubMed/28690878" } ], "site_lbl": "Tyr523" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "147", "end_pos": "147" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "586", "end_pos": "586" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9QUG9-1.554.554", "start_pos": 554, "end_pos": 554, "uniprot_canonical_ac": "Q9QUG9-1", "length": 608, "uniprot_id": "GRP2_MOUSE", "protein_name": "RAS guanyl-releasing protein 2", "refseq_ac": "NP_035372", "refseq_name": "RAS guanyl-releasing protein 2 isoform 1", "gene_name": "Rasgrp2", "gene_names_uniprotkb": "Rasgrp2", "gene_names_refseq": "CDC25L; CalDAG-GEFI; Caldaggef1; Rasgrp2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9QUG9", "url": "https://www.uniprot.org/uniprotkb/Q9QUG9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9QUG9", "url": "https://www.uniprot.org/uniprotkb/Q9QUG9" }, { "database": "iPTMnet", "id": "Q9QUG9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9QUG9" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q9QUG9", "url": "https://www.uniprot.org/uniprotkb/Q9QUG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9QUG9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9QUG9", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VNCHKQCKERLSVECRRRAQ", "down_seq": "VSLEGSAPSPSPTHTHHRAF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9QUG9", "url": "https://www.uniprot.org/uniprotkb/Q9QUG9" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q9QUG9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9QUG9" } ], "site_lbl": "Ser554" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "147", "end_pos": "147" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "586", "end_pos": "586" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9QUG9-1.575.575", "start_pos": 575, "end_pos": 575, "uniprot_canonical_ac": "Q9QUG9-1", "length": 608, "uniprot_id": "GRP2_MOUSE", "protein_name": "RAS guanyl-releasing protein 2", "refseq_ac": "NP_035372", "refseq_name": "RAS guanyl-releasing protein 2 isoform 1", "gene_name": "Rasgrp2", "gene_names_uniprotkb": "Rasgrp2", "gene_names_refseq": "CDC25L; CalDAG-GEFI; Caldaggef1; Rasgrp2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9QUG9", "url": "https://www.uniprot.org/uniprotkb/Q9QUG9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9QUG9", "url": "https://www.uniprot.org/uniprotkb/Q9QUG9", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VSLEGSAPSPSPTHTHHRAF", "down_seq": "FSLPRPGRRSSRPPEIREEE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9QUG9", "url": "https://www.uniprot.org/uniprotkb/Q9QUG9" } ], "site_lbl": "Ser575" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "147", "end_pos": "147" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "586", "end_pos": "586" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "upstream", "id": "Q9QUG9-1.586.586", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9QUG9-1.586.586", "start_pos": 586, "end_pos": 586, "uniprot_canonical_ac": "Q9QUG9-1", "length": 608, "uniprot_id": "GRP2_MOUSE", "protein_name": "RAS guanyl-releasing protein 2", "refseq_ac": "NP_035372", "refseq_name": "RAS guanyl-releasing protein 2 isoform 1", "gene_name": "Rasgrp2", "gene_names_uniprotkb": "Rasgrp2", "gene_names_refseq": "CDC25L; CalDAG-GEFI; Caldaggef1; Rasgrp2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9QUG9", "url": "https://www.uniprot.org/uniprotkb/Q9QUG9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "DARPP-32/protein phosphatase 1 regulates Rasgrp2 as a novel component of dopamine D1 receptor signaling in striatum.", "journal": "Neurochemistry international", "date": "2022-11-06", "authors": "Kuroiwa Mahomi, Shuto Takahide, Nagai Taku, Amano Mutsuki, Kaibuchi Kozo, Nairn Angus C, Nishi Akinori", "evidence": [ { "database": "iPTMnet", "id": "Q9QUG9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9QUG9" } ], "reference": [ { "type": "PubMed", "id": "36351540", "url": "https://glygen.org/publication/PubMed/36351540" } ] } ], "crossref": [ { "id": "Q9QUG9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9QUG9", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "36351540", "url": "https://glygen.org/publication/PubMed/36351540", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PTHTHHRAFSFSLPRPGRRS", "down_seq": "RPPEIREEEVQSVEDGVFDI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q9QUG9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9QUG9" }, { "database": "PubMed", "id": "36351540", "url": "https://glygen.org/publication/PubMed/36351540" } ], "site_lbl": "Ser586" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "147", "end_pos": "147" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "586", "end_pos": "586" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "Q9QUG9-1.575.575", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03267-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Dynamic O-GlcNAcylation governs long-range chromatin interactions in V(D)J recombination during early B-cell development.", "journal": "Cellular & molecular immunology", "date": "2025-01", "authors": "Jeon Bong Chan, Kim Yu-Ji, Park Ae Kyung, Song Mi-Ran, Na Ki Myeong, Lee Juwon, An Dasom, Park Yeseul, Hwang Heeyoun, Kim Tae-Don, Lim Junghyun, Park Sung-Kyun", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q03267", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q03267" } ], "reference": [ { "type": "PubMed", "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609" } ] } ], "crossref": [ { "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q03267", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q03267", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "39627609", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39627609" }, { "id": "Q03267", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q03267" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "upstream", "id": "Q03267-1.13.13", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03267-1.101.101", "start_pos": 101, "end_pos": 101, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Recruitment of ikaros to pericentromeric heterochromatin is regulated by phosphorylation.", "journal": "The Journal of biological chemistry", "date": "2008", "authors": "Gurel Z, Ronni T, Ho S, Kuchar J, Payne KJ, Turk CW, Dovat S", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "iPTMnet", "id": "Q03267", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03267" } ], "reference": [ { "type": "PubMed", "id": "18223295", "url": "https://glygen.org/publication/PubMed/18223295" } ] } ], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18223295", "url": "https://glygen.org/publication/PubMed/18223295", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q03267", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03267", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DLRMLDASGEKMNGSHRDQG", "down_seq": "SALSGVGGIRLPNGKLKCDI", "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Abolishes phosphorylation. No change in pericentromeric location.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "18223295", "url": "https://glygen.org/publication/PubMed/18223295" } ] }, { "sequence_org": "S", "sequence_mut": "D", "comment": "No change in binding to gamma satellites A and B. No change in pericentromeric location.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "18223295", "url": "https://glygen.org/publication/PubMed/18223295" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "18223295", "url": "https://glygen.org/publication/PubMed/18223295" }, { "database": "iPTMnet", "id": "Q03267", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03267" } ], "site_lbl": "Ser101" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "mutagenesis_flag", "phosphorylation_flag" ], "glycosylation": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03267-1.13.13", "start_pos": 13, "end_pos": 13, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Recruitment of ikaros to pericentromeric heterochromatin is regulated by phosphorylation.", "journal": "The Journal of biological chemistry", "date": "2008", "authors": "Gurel Z, Ronni T, Ho S, Kuchar J, Payne KJ, Turk CW, Dovat S", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "iPTMnet", "id": "Q03267", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03267" } ], "reference": [ { "type": "PubMed", "id": "18223295", "url": "https://glygen.org/publication/PubMed/18223295" } ] } ], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18223295", "url": "https://glygen.org/publication/PubMed/18223295", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q03267", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03267", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MDVDEGQDMSQV", "down_seq": "GKESPPVSDTPDEGDEPMPV", "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Abolishes phosphorylation. No change in binding to gamma satellites A and B. No change in pericentromeric location. Increased DNA binding affinity toward TDT.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "18223295", "url": "https://glygen.org/publication/PubMed/18223295" } ] }, { "sequence_org": "S", "sequence_mut": "D", "comment": "Decreased binding to gamma satellite A by 5-fold and to gamma satellite B by 3-fold. Diffuse nuclear location.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "18223295", "url": "https://glygen.org/publication/PubMed/18223295" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "18223295", "url": "https://glygen.org/publication/PubMed/18223295" }, { "database": "iPTMnet", "id": "Q03267", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03267" } ], "site_lbl": "Ser13" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "mutagenesis_flag", "phosphorylation_flag" ], "glycosylation": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "Q03267-1.0.0", "categories": [ "glycosylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q03267-1.23.23", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03267-1.140.140", "start_pos": 140, "end_pos": 140, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A common mechanism for mitotic inactivation of C2H2 zinc finger DNA-binding domains.", "journal": "Genes & development", "date": "2002", "authors": "Dovat S, Ronni T, Russell D, Ferrini R, Cobb BS, Smale ST", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "iPTMnet", "id": "Q03267", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03267" } ], "reference": [ { "type": "PubMed", "id": "12464629", "url": "https://glygen.org/publication/PubMed/12464629" } ] } ], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "12464629", "url": "https://glygen.org/publication/PubMed/12464629", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q03267", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03267", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "DICGIVCIGPNVLMVHKRSH", "down_seq": "ERPFQCNQCGASFTQKGNLL", "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Abolishes phosphorylation, DNA binding and pericentromeric location. Loss of DNA binding and pericentromeric location; when associated with A-167 and A-195.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "12464629", "url": "https://glygen.org/publication/PubMed/12464629" } ] }, { "sequence_org": "T", "sequence_mut": "E", "comment": "Abolishes phosphorylation, DNA binding and pericentromeric location. Loss of DNA binding and pericentromeric location; when associated with E-167 and D-195.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "12464629", "url": "https://glygen.org/publication/PubMed/12464629" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "12464629", "url": "https://glygen.org/publication/PubMed/12464629" }, { "database": "iPTMnet", "id": "Q03267", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03267" } ], "site_lbl": "Thr140" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "mutagenesis_flag", "phosphorylation_flag" ], "glycosylation": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "upstream", "id": "Q03267-1.152.152", "categories": [ "mutagenesis_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q03267-1.153.153", "categories": [ "mutagenesis_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q03267-1.154.154", "categories": [ "mutagenesis_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q03267-1.155.155", "categories": [ "mutagenesis_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q03267-1.156.156", "categories": [ "mutagenesis_flag" ] }, { "distance": 17, "direction": "upstream", "id": "Q03267-1.157.157", "categories": [ "mutagenesis_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q03267-1.158.158", "categories": [ "mutagenesis_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q03267-1.159.159", "categories": [ "mutagenesis_flag" ] }, { "distance": 20, "direction": "upstream", "id": "Q03267-1.160.160", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03267-1.152.152", "start_pos": 152, "end_pos": 152, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding.", "journal": "Genes & development", "date": "2000", "authors": "Cobb BS, Morales-Alcelay S, Kleiger G, Brown KE, Fisher AG, Smale ST", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "reference": [ { "type": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LMVHKRSHTERPFQCNQCGA", "down_seq": "FTQKGNLLRHIKLHSGEKPF", "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "No effect on pericentromeric heterochromatin location. No change in DNA binding.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "Q03267-1.140.140", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q03267-1.153.153", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q03267-1.154.154", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q03267-1.155.155", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q03267-1.156.156", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q03267-1.157.157", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q03267-1.158.158", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q03267-1.159.159", "categories": [ "mutagenesis_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q03267-1.160.160", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q03267-1.161.161", "categories": [ "mutagenesis_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q03267-1.167.167", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03267-1.153.153", "start_pos": 153, "end_pos": 153, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding.", "journal": "Genes & development", "date": "2000", "authors": "Cobb BS, Morales-Alcelay S, Kleiger G, Brown KE, Fisher AG, Smale ST", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "reference": [ { "type": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "F", "start_aa": "F", "up_seq": "MVHKRSHTERPFQCNQCGAS", "down_seq": "TQKGNLLRHIKLHSGEKPFK", "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "A", "comment": "Disrupts pericentromeric heterochromatin location. Partial cytoplasmic location. Abolishes DNA binding.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "Q03267-1.140.140", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q03267-1.152.152", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q03267-1.154.154", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q03267-1.155.155", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q03267-1.156.156", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q03267-1.157.157", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q03267-1.158.158", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q03267-1.159.159", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q03267-1.160.160", "categories": [ "mutagenesis_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q03267-1.161.161", "categories": [ "mutagenesis_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q03267-1.167.167", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "Q03267-1.173.173", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03267-1.154.154", "start_pos": 154, "end_pos": 154, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding.", "journal": "Genes & development", "date": "2000", "authors": "Cobb BS, Morales-Alcelay S, Kleiger G, Brown KE, Fisher AG, Smale ST", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "reference": [ { "type": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "VHKRSHTERPFQCNQCGASF", "down_seq": "QKGNLLRHIKLHSGEKPFKC", "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "No effect on pericentromeric heterochromatin location. No change in DNA binding.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "Q03267-1.140.140", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q03267-1.152.152", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q03267-1.153.153", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q03267-1.155.155", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q03267-1.156.156", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q03267-1.157.157", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q03267-1.158.158", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q03267-1.159.159", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q03267-1.160.160", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q03267-1.161.161", "categories": [ "mutagenesis_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q03267-1.167.167", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q03267-1.173.173", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03267-1.155.155", "start_pos": 155, "end_pos": 155, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding.", "journal": "Genes & development", "date": "2000", "authors": "Cobb BS, Morales-Alcelay S, Kleiger G, Brown KE, Fisher AG, Smale ST", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "reference": [ { "type": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Q", "start_aa": "Q", "up_seq": "HKRSHTERPFQCNQCGASFT", "down_seq": "KGNLLRHIKLHSGEKPFKCH", "mutagenesis": [ { "sequence_org": "Q", "sequence_mut": "A", "comment": "Loss of pericentromeric heterochromatin location. Disrupted DNA binding.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "Q03267-1.140.140", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q03267-1.152.152", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q03267-1.153.153", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q03267-1.154.154", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q03267-1.156.156", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q03267-1.157.157", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q03267-1.158.158", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q03267-1.159.159", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q03267-1.160.160", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q03267-1.161.161", "categories": [ "mutagenesis_flag" ] }, { "distance": 12, "direction": "upstream", "id": "Q03267-1.167.167", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q03267-1.173.173", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03267-1.156.156", "start_pos": 156, "end_pos": 156, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding.", "journal": "Genes & development", "date": "2000", "authors": "Cobb BS, Morales-Alcelay S, Kleiger G, Brown KE, Fisher AG, Smale ST", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "reference": [ { "type": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "KRSHTERPFQCNQCGASFTQ", "down_seq": "GNLLRHIKLHSGEKPFKCHL", "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Disrupts pericentromeric heterochromatin location. Partial cytoplasmic location.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "Q03267-1.140.140", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q03267-1.152.152", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q03267-1.153.153", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q03267-1.154.154", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q03267-1.155.155", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q03267-1.157.157", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q03267-1.158.158", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q03267-1.159.159", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q03267-1.160.160", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q03267-1.161.161", "categories": [ "mutagenesis_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q03267-1.167.167", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "Q03267-1.173.173", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03267-1.157.157", "start_pos": 157, "end_pos": 157, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding.", "journal": "Genes & development", "date": "2000", "authors": "Cobb BS, Morales-Alcelay S, Kleiger G, Brown KE, Fisher AG, Smale ST", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "reference": [ { "type": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "G", "start_aa": "G", "up_seq": "RSHTERPFQCNQCGASFTQK", "down_seq": "NLLRHIKLHSGEKPFKCHLC", "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "A", "comment": "Loss of pericentromeric heterochromatin location. Disrupted DNA binding.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "Q03267-1.140.140", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q03267-1.152.152", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q03267-1.153.153", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q03267-1.154.154", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q03267-1.155.155", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q03267-1.156.156", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q03267-1.158.158", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q03267-1.159.159", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q03267-1.160.160", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q03267-1.161.161", "categories": [ "mutagenesis_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q03267-1.167.167", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q03267-1.173.173", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03267-1.158.158", "start_pos": 158, "end_pos": 158, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding.", "journal": "Genes & development", "date": "2000", "authors": "Cobb BS, Morales-Alcelay S, Kleiger G, Brown KE, Fisher AG, Smale ST", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "reference": [ { "type": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "SHTERPFQCNQCGASFTQKG", "down_seq": "LLRHIKLHSGEKPFKCHLCN", "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "A", "comment": "Loss of pericentromeric heterochromatin location. Abolishes DNA binding.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "Q03267-1.140.140", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q03267-1.152.152", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q03267-1.153.153", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q03267-1.154.154", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q03267-1.155.155", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q03267-1.156.156", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q03267-1.157.157", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q03267-1.159.159", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q03267-1.160.160", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q03267-1.161.161", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q03267-1.167.167", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q03267-1.173.173", "categories": [ "mutagenesis_flag" ] }, { "distance": 20, "direction": "upstream", "id": "Q03267-1.178.178", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03267-1.159.159", "start_pos": 159, "end_pos": 159, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding.", "journal": "Genes & development", "date": "2000", "authors": "Cobb BS, Morales-Alcelay S, Kleiger G, Brown KE, Fisher AG, Smale ST", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "reference": [ { "type": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "L", "start_aa": "L", "up_seq": "HTERPFQCNQCGASFTQKGN", "down_seq": "LRHIKLHSGEKPFKCHLCNY", "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "A", "comment": "No effect on pericentromeric heterochromatin location. No change in DNA binding.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "Q03267-1.140.140", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "Q03267-1.152.152", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q03267-1.153.153", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q03267-1.154.154", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q03267-1.155.155", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q03267-1.156.156", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q03267-1.157.157", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q03267-1.158.158", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q03267-1.160.160", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q03267-1.161.161", "categories": [ "mutagenesis_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q03267-1.167.167", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q03267-1.173.173", "categories": [ "mutagenesis_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q03267-1.178.178", "categories": [ "mutagenesis_flag" ] }, { "distance": 20, "direction": "upstream", "id": "Q03267-1.179.179", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03267-1.160.160", "start_pos": 160, "end_pos": 160, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding.", "journal": "Genes & development", "date": "2000", "authors": "Cobb BS, Morales-Alcelay S, Kleiger G, Brown KE, Fisher AG, Smale ST", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "reference": [ { "type": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "L", "start_aa": "L", "up_seq": "TERPFQCNQCGASFTQKGNL", "down_seq": "RHIKLHSGEKPFKCHLCNYA", "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "A", "comment": "No effect on pericentromeric heterochromatin location. No change in DNA binding.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "Q03267-1.140.140", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "Q03267-1.152.152", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "downstream", "id": "Q03267-1.153.153", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q03267-1.154.154", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q03267-1.155.155", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q03267-1.156.156", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q03267-1.157.157", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q03267-1.158.158", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q03267-1.159.159", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q03267-1.161.161", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q03267-1.167.167", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q03267-1.173.173", "categories": [ "mutagenesis_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q03267-1.178.178", "categories": [ "mutagenesis_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q03267-1.179.179", "categories": [ "mutagenesis_flag" ] }, { "distance": 20, "direction": "upstream", "id": "Q03267-1.180.180", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03267-1.161.161", "start_pos": 161, "end_pos": 161, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding.", "journal": "Genes & development", "date": "2000", "authors": "Cobb BS, Morales-Alcelay S, Kleiger G, Brown KE, Fisher AG, Smale ST", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "reference": [ { "type": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "ERPFQCNQCGASFTQKGNLL", "down_seq": "HIKLHSGEKPFKCHLCNYAC", "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Disrupts pericentromeric heterochromatin location. Partial cytoplasmic location. Abolishes DNA binding.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "Q03267-1.152.152", "categories": [ "mutagenesis_flag" ] }, { "distance": 8, "direction": "downstream", "id": "Q03267-1.153.153", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "downstream", "id": "Q03267-1.154.154", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q03267-1.155.155", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q03267-1.156.156", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q03267-1.157.157", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q03267-1.158.158", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q03267-1.159.159", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q03267-1.160.160", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q03267-1.167.167", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "Q03267-1.173.173", "categories": [ "mutagenesis_flag" ] }, { "distance": 17, "direction": "upstream", "id": "Q03267-1.178.178", "categories": [ "mutagenesis_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q03267-1.179.179", "categories": [ "mutagenesis_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q03267-1.180.180", "categories": [ "mutagenesis_flag" ] }, { "distance": 20, "direction": "upstream", "id": "Q03267-1.181.181", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03267-1.167.167", "start_pos": 167, "end_pos": 167, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A common mechanism for mitotic inactivation of C2H2 zinc finger DNA-binding domains.", "journal": "Genes & development", "date": "2002", "authors": "Dovat S, Ronni T, Russell D, Ferrini R, Cobb BS, Smale ST", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "iPTMnet", "id": "Q03267", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03267" } ], "reference": [ { "type": "PubMed", "id": "12464629", "url": "https://glygen.org/publication/PubMed/12464629" } ] } ], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "12464629", "url": "https://glygen.org/publication/PubMed/12464629", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q03267", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03267", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NQCGASFTQKGNLLRHIKLH", "down_seq": "GEKPFKCHLCNYACRRRDAL", "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Abolishes phosphorylation, no effect on DNA binding nor on pericentromeric location. Loss of DNA binding and pericentromeric location; when associated with A-140 and A-195.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "12464629", "url": "https://glygen.org/publication/PubMed/12464629" } ] }, { "sequence_org": "S", "sequence_mut": "E", "comment": "Abolishes phosphorylation, no effect on DNA binding nor on pericentromeric location. Loss of DNA binding and pericentromeric location; when associated with E-140 and D-195.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "12464629", "url": "https://glygen.org/publication/PubMed/12464629" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "12464629", "url": "https://glygen.org/publication/PubMed/12464629" }, { "database": "iPTMnet", "id": "Q03267", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03267" } ], "site_lbl": "Ser167" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "mutagenesis_flag", "phosphorylation_flag" ], "glycosylation": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "Q03267-1.152.152", "categories": [ "mutagenesis_flag" ] }, { "distance": 14, "direction": "downstream", "id": "Q03267-1.153.153", "categories": [ "mutagenesis_flag" ] }, { "distance": 13, "direction": "downstream", "id": "Q03267-1.154.154", "categories": [ "mutagenesis_flag" ] }, { "distance": 12, "direction": "downstream", "id": "Q03267-1.155.155", "categories": [ "mutagenesis_flag" ] }, { "distance": 11, "direction": "downstream", "id": "Q03267-1.156.156", "categories": [ "mutagenesis_flag" ] }, { "distance": 10, "direction": "downstream", "id": "Q03267-1.157.157", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "downstream", "id": "Q03267-1.158.158", "categories": [ "mutagenesis_flag" ] }, { "distance": 8, "direction": "downstream", "id": "Q03267-1.159.159", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "downstream", "id": "Q03267-1.160.160", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q03267-1.161.161", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q03267-1.173.173", "categories": [ "mutagenesis_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q03267-1.178.178", "categories": [ "mutagenesis_flag" ] }, { "distance": 12, "direction": "upstream", "id": "Q03267-1.179.179", "categories": [ "mutagenesis_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q03267-1.180.180", "categories": [ "mutagenesis_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q03267-1.181.181", "categories": [ "mutagenesis_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q03267-1.182.182", "categories": [ "mutagenesis_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q03267-1.183.183", "categories": [ "mutagenesis_flag" ] }, { "distance": 17, "direction": "upstream", "id": "Q03267-1.184.184", "categories": [ "mutagenesis_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q03267-1.185.185", "categories": [ "mutagenesis_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q03267-1.186.186", "categories": [ "mutagenesis_flag" ] }, { "distance": 20, "direction": "upstream", "id": "Q03267-1.187.187", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03267-1.173.173", "start_pos": 173, "end_pos": 173, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding.", "journal": "Genes & development", "date": "2000", "authors": "Cobb BS, Morales-Alcelay S, Kleiger G, Brown KE, Fisher AG, Smale ST", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "reference": [ { "type": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "FTQKGNLLRHIKLHSGEKPF", "down_seq": "CHLCNYACRRRDALTGHLRT", "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "No effect on pericentromeric heterochromatin location. No change in DNA binding.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "Q03267-1.153.153", "categories": [ "mutagenesis_flag" ] }, { "distance": 19, "direction": "downstream", "id": "Q03267-1.154.154", "categories": [ "mutagenesis_flag" ] }, { "distance": 18, "direction": "downstream", "id": "Q03267-1.155.155", "categories": [ "mutagenesis_flag" ] }, { "distance": 17, "direction": "downstream", "id": "Q03267-1.156.156", "categories": [ "mutagenesis_flag" ] }, { "distance": 16, "direction": "downstream", "id": "Q03267-1.157.157", "categories": [ "mutagenesis_flag" ] }, { "distance": 15, "direction": "downstream", "id": "Q03267-1.158.158", "categories": [ "mutagenesis_flag" ] }, { "distance": 14, "direction": "downstream", "id": "Q03267-1.159.159", "categories": [ "mutagenesis_flag" ] }, { "distance": 13, "direction": "downstream", "id": "Q03267-1.160.160", "categories": [ "mutagenesis_flag" ] }, { "distance": 12, "direction": "downstream", "id": "Q03267-1.161.161", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q03267-1.167.167", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q03267-1.178.178", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q03267-1.179.179", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q03267-1.180.180", "categories": [ "mutagenesis_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q03267-1.181.181", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q03267-1.182.182", "categories": [ "mutagenesis_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q03267-1.183.183", "categories": [ "mutagenesis_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q03267-1.184.184", "categories": [ "mutagenesis_flag" ] }, { "distance": 12, "direction": "upstream", "id": "Q03267-1.185.185", "categories": [ "mutagenesis_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q03267-1.186.186", "categories": [ "mutagenesis_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q03267-1.187.187", "categories": [ "mutagenesis_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q03267-1.188.188", "categories": [ "mutagenesis_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q03267-1.189.189", "categories": [ "mutagenesis_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q03267-1.191.191", "categories": [ "mutagenesis_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q03267-1.192.192", "categories": [ "mutagenesis_flag" ] }, { "distance": 20, "direction": "upstream", "id": "Q03267-1.193.193", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03267-1.178.178", "start_pos": 178, "end_pos": 178, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding.", "journal": "Genes & development", "date": "2000", "authors": "Cobb BS, Morales-Alcelay S, Kleiger G, Brown KE, Fisher AG, Smale ST", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "reference": [ { "type": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "NLLRHIKLHSGEKPFKCHLC", "down_seq": "YACRRRDALTGHLRTHSVGK", "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "A", "comment": "No effect on pericentromeric heterochromatin location. No change in DNA binding.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "Q03267-1.158.158", "categories": [ "mutagenesis_flag" ] }, { "distance": 19, "direction": "downstream", "id": "Q03267-1.159.159", "categories": [ "mutagenesis_flag" ] }, { "distance": 18, "direction": "downstream", "id": "Q03267-1.160.160", "categories": [ "mutagenesis_flag" ] }, { "distance": 17, "direction": "downstream", "id": "Q03267-1.161.161", "categories": [ "mutagenesis_flag" ] }, { "distance": 11, "direction": "downstream", "id": "Q03267-1.167.167", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q03267-1.173.173", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q03267-1.179.179", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q03267-1.180.180", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q03267-1.181.181", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q03267-1.182.182", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q03267-1.183.183", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q03267-1.184.184", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q03267-1.185.185", "categories": [ "mutagenesis_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q03267-1.186.186", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q03267-1.187.187", "categories": [ "mutagenesis_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q03267-1.188.188", "categories": [ "mutagenesis_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q03267-1.189.189", "categories": [ "mutagenesis_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q03267-1.191.191", "categories": [ "mutagenesis_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q03267-1.192.192", "categories": [ "mutagenesis_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q03267-1.193.193", "categories": [ "mutagenesis_flag" ] }, { "distance": 17, "direction": "upstream", "id": "Q03267-1.195.195", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03267-1.179.179", "start_pos": 179, "end_pos": 179, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding.", "journal": "Genes & development", "date": "2000", "authors": "Cobb BS, Morales-Alcelay S, Kleiger G, Brown KE, Fisher AG, Smale ST", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "reference": [ { "type": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "LLRHIKLHSGEKPFKCHLCN", "down_seq": "ACRRRDALTGHLRTHSVGKP", "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "A", "comment": "Loss of pericentromeric heterochromatin location. Abolishes DNA binding.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "Q03267-1.159.159", "categories": [ "mutagenesis_flag" ] }, { "distance": 19, "direction": "downstream", "id": "Q03267-1.160.160", "categories": [ "mutagenesis_flag" ] }, { "distance": 18, "direction": "downstream", "id": "Q03267-1.161.161", "categories": [ "mutagenesis_flag" ] }, { "distance": 12, "direction": "downstream", "id": "Q03267-1.167.167", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q03267-1.173.173", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q03267-1.178.178", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q03267-1.180.180", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q03267-1.181.181", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q03267-1.182.182", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q03267-1.183.183", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q03267-1.184.184", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q03267-1.185.185", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q03267-1.186.186", "categories": [ "mutagenesis_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q03267-1.187.187", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q03267-1.188.188", "categories": [ "mutagenesis_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q03267-1.189.189", "categories": [ "mutagenesis_flag" ] }, { "distance": 12, "direction": "upstream", "id": "Q03267-1.191.191", "categories": [ "mutagenesis_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q03267-1.192.192", "categories": [ "mutagenesis_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q03267-1.193.193", "categories": [ "mutagenesis_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q03267-1.195.195", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03267-1.180.180", "start_pos": 180, "end_pos": 180, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding.", "journal": "Genes & development", "date": "2000", "authors": "Cobb BS, Morales-Alcelay S, Kleiger G, Brown KE, Fisher AG, Smale ST", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "reference": [ { "type": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "A", "start_aa": "A", "up_seq": "LRHIKLHSGEKPFKCHLCNY", "down_seq": "CRRRDALTGHLRTHSVGKPH", "mutagenesis": [ { "sequence_org": "A", "sequence_mut": "L", "comment": "Loss of pericentromeric heterochromatin location. Disrupted DNA binding.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "Q03267-1.160.160", "categories": [ "mutagenesis_flag" ] }, { "distance": 19, "direction": "downstream", "id": "Q03267-1.161.161", "categories": [ "mutagenesis_flag" ] }, { "distance": 13, "direction": "downstream", "id": "Q03267-1.167.167", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "Q03267-1.173.173", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q03267-1.178.178", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q03267-1.179.179", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q03267-1.181.181", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q03267-1.182.182", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q03267-1.183.183", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q03267-1.184.184", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q03267-1.185.185", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q03267-1.186.186", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q03267-1.187.187", "categories": [ "mutagenesis_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q03267-1.188.188", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q03267-1.189.189", "categories": [ "mutagenesis_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q03267-1.191.191", "categories": [ "mutagenesis_flag" ] }, { "distance": 12, "direction": "upstream", "id": "Q03267-1.192.192", "categories": [ "mutagenesis_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q03267-1.193.193", "categories": [ "mutagenesis_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q03267-1.195.195", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03267-1.181.181", "start_pos": 181, "end_pos": 181, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding.", "journal": "Genes & development", "date": "2000", "authors": "Cobb BS, Morales-Alcelay S, Kleiger G, Brown KE, Fisher AG, Smale ST", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "reference": [ { "type": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "C", "start_aa": "C", "up_seq": "RHIKLHSGEKPFKCHLCNYA", "down_seq": "RRRDALTGHLRTHSVGKPHK", "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "No effect on pericentromeric heterochromatin location. No change in DNA binding.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "Q03267-1.161.161", "categories": [ "mutagenesis_flag" ] }, { "distance": 14, "direction": "downstream", "id": "Q03267-1.167.167", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "Q03267-1.173.173", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q03267-1.178.178", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q03267-1.179.179", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q03267-1.180.180", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q03267-1.182.182", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q03267-1.183.183", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q03267-1.184.184", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q03267-1.185.185", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q03267-1.186.186", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q03267-1.187.187", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q03267-1.188.188", "categories": [ "mutagenesis_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q03267-1.189.189", "categories": [ "mutagenesis_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q03267-1.191.191", "categories": [ "mutagenesis_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q03267-1.192.192", "categories": [ "mutagenesis_flag" ] }, { "distance": 12, "direction": "upstream", "id": "Q03267-1.193.193", "categories": [ "mutagenesis_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q03267-1.195.195", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03267-1.182.182", "start_pos": 182, "end_pos": 182, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding.", "journal": "Genes & development", "date": "2000", "authors": "Cobb BS, Morales-Alcelay S, Kleiger G, Brown KE, Fisher AG, Smale ST", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "reference": [ { "type": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "HIKLHSGEKPFKCHLCNYAC", "down_seq": "RRDALTGHLRTHSVGKPHKC", "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "No effect on pericentromeric heterochromatin location. No change in DNA binding.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "Q03267-1.167.167", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "Q03267-1.173.173", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q03267-1.178.178", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q03267-1.179.179", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q03267-1.180.180", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q03267-1.181.181", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q03267-1.183.183", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q03267-1.184.184", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q03267-1.185.185", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q03267-1.186.186", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q03267-1.187.187", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q03267-1.188.188", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q03267-1.189.189", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q03267-1.191.191", "categories": [ "mutagenesis_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q03267-1.192.192", "categories": [ "mutagenesis_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q03267-1.193.193", "categories": [ "mutagenesis_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q03267-1.195.195", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03267-1.183.183", "start_pos": 183, "end_pos": 183, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding.", "journal": "Genes & development", "date": "2000", "authors": "Cobb BS, Morales-Alcelay S, Kleiger G, Brown KE, Fisher AG, Smale ST", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "reference": [ { "type": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "IKLHSGEKPFKCHLCNYACR", "down_seq": "RDALTGHLRTHSVGKPHKCG", "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Disrupts pericentromeric heterochromatin location. Partial cytoplasmic location. Abolishes DNA binding.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "Q03267-1.167.167", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "Q03267-1.173.173", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q03267-1.178.178", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q03267-1.179.179", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q03267-1.180.180", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q03267-1.181.181", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q03267-1.182.182", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q03267-1.184.184", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q03267-1.185.185", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q03267-1.186.186", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q03267-1.187.187", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q03267-1.188.188", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q03267-1.189.189", "categories": [ "mutagenesis_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q03267-1.191.191", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q03267-1.192.192", "categories": [ "mutagenesis_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q03267-1.193.193", "categories": [ "mutagenesis_flag" ] }, { "distance": 12, "direction": "upstream", "id": "Q03267-1.195.195", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03267-1.184.184", "start_pos": 184, "end_pos": 184, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding.", "journal": "Genes & development", "date": "2000", "authors": "Cobb BS, Morales-Alcelay S, Kleiger G, Brown KE, Fisher AG, Smale ST", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "reference": [ { "type": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "KLHSGEKPFKCHLCNYACRR", "down_seq": "DALTGHLRTHSVGKPHKCGY", "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "No effect on pericentromeric heterochromatin location. No change in DNA binding.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "Q03267-1.167.167", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "Q03267-1.173.173", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q03267-1.178.178", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q03267-1.179.179", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q03267-1.180.180", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q03267-1.181.181", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q03267-1.182.182", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q03267-1.183.183", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q03267-1.185.185", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q03267-1.186.186", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q03267-1.187.187", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q03267-1.188.188", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q03267-1.189.189", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q03267-1.191.191", "categories": [ "mutagenesis_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q03267-1.192.192", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q03267-1.193.193", "categories": [ "mutagenesis_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q03267-1.195.195", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03267-1.185.185", "start_pos": 185, "end_pos": 185, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding.", "journal": "Genes & development", "date": "2000", "authors": "Cobb BS, Morales-Alcelay S, Kleiger G, Brown KE, Fisher AG, Smale ST", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "reference": [ { "type": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "LHSGEKPFKCHLCNYACRRR", "down_seq": "ALTGHLRTHSVGKPHKCGYC", "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "No effect on pericentromeric heterochromatin location. Disrupted DNA binding.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "Q03267-1.167.167", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "Q03267-1.173.173", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "downstream", "id": "Q03267-1.178.178", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q03267-1.179.179", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q03267-1.180.180", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q03267-1.181.181", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q03267-1.182.182", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q03267-1.183.183", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q03267-1.184.184", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q03267-1.186.186", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q03267-1.187.187", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q03267-1.188.188", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q03267-1.189.189", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q03267-1.191.191", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q03267-1.192.192", "categories": [ "mutagenesis_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q03267-1.193.193", "categories": [ "mutagenesis_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q03267-1.195.195", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03267-1.186.186", "start_pos": 186, "end_pos": 186, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding.", "journal": "Genes & development", "date": "2000", "authors": "Cobb BS, Morales-Alcelay S, Kleiger G, Brown KE, Fisher AG, Smale ST", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "reference": [ { "type": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "A", "start_aa": "A", "up_seq": "HSGEKPFKCHLCNYACRRRD", "down_seq": "LTGHLRTHSVGKPHKCGYCG", "mutagenesis": [ { "sequence_org": "A", "sequence_mut": "L", "comment": "No effect on pericentromeric heterochromatin location. Disrupted DNA binding.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "Q03267-1.167.167", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "Q03267-1.173.173", "categories": [ "mutagenesis_flag" ] }, { "distance": 8, "direction": "downstream", "id": "Q03267-1.178.178", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "downstream", "id": "Q03267-1.179.179", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q03267-1.180.180", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q03267-1.181.181", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q03267-1.182.182", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q03267-1.183.183", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q03267-1.184.184", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q03267-1.185.185", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q03267-1.187.187", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q03267-1.188.188", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q03267-1.189.189", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q03267-1.191.191", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q03267-1.192.192", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q03267-1.193.193", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q03267-1.195.195", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03267-1.187.187", "start_pos": 187, "end_pos": 187, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding.", "journal": "Genes & development", "date": "2000", "authors": "Cobb BS, Morales-Alcelay S, Kleiger G, Brown KE, Fisher AG, Smale ST", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "reference": [ { "type": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "L", "start_aa": "L", "up_seq": "SGEKPFKCHLCNYACRRRDA", "down_seq": "TGHLRTHSVGKPHKCGYCGR", "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "A", "comment": "Loss of pericentromeric heterochromatin location. Abolishes DNA binding.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "Q03267-1.167.167", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "Q03267-1.173.173", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "downstream", "id": "Q03267-1.178.178", "categories": [ "mutagenesis_flag" ] }, { "distance": 8, "direction": "downstream", "id": "Q03267-1.179.179", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "downstream", "id": "Q03267-1.180.180", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q03267-1.181.181", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q03267-1.182.182", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q03267-1.183.183", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q03267-1.184.184", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q03267-1.185.185", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q03267-1.186.186", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q03267-1.188.188", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q03267-1.189.189", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q03267-1.191.191", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q03267-1.192.192", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q03267-1.193.193", "categories": [ "mutagenesis_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q03267-1.195.195", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03267-1.188.188", "start_pos": 188, "end_pos": 188, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding.", "journal": "Genes & development", "date": "2000", "authors": "Cobb BS, Morales-Alcelay S, Kleiger G, Brown KE, Fisher AG, Smale ST", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "reference": [ { "type": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "GEKPFKCHLCNYACRRRDAL", "down_seq": "GHLRTHSVGKPHKCGYCGRS", "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "No effect on pericentromeric heterochromatin location. No change in DNA binding.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "Q03267-1.173.173", "categories": [ "mutagenesis_flag" ] }, { "distance": 10, "direction": "downstream", "id": "Q03267-1.178.178", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "downstream", "id": "Q03267-1.179.179", "categories": [ "mutagenesis_flag" ] }, { "distance": 8, "direction": "downstream", "id": "Q03267-1.180.180", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "downstream", "id": "Q03267-1.181.181", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q03267-1.182.182", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q03267-1.183.183", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q03267-1.184.184", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q03267-1.185.185", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q03267-1.186.186", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q03267-1.187.187", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q03267-1.189.189", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q03267-1.191.191", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q03267-1.192.192", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q03267-1.193.193", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q03267-1.195.195", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03267-1.189.189", "start_pos": 189, "end_pos": 189, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding.", "journal": "Genes & development", "date": "2000", "authors": "Cobb BS, Morales-Alcelay S, Kleiger G, Brown KE, Fisher AG, Smale ST", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "reference": [ { "type": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "G", "start_aa": "G", "up_seq": "EKPFKCHLCNYACRRRDALT", "down_seq": "HLRTHSVGKPHKCGYCGRSY", "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "A", "comment": "No effect on pericentromeric heterochromatin location. No change in DNA binding.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "Q03267-1.173.173", "categories": [ "mutagenesis_flag" ] }, { "distance": 11, "direction": "downstream", "id": "Q03267-1.178.178", "categories": [ "mutagenesis_flag" ] }, { "distance": 10, "direction": "downstream", "id": "Q03267-1.179.179", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "downstream", "id": "Q03267-1.180.180", "categories": [ "mutagenesis_flag" ] }, { "distance": 8, "direction": "downstream", "id": "Q03267-1.181.181", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "downstream", "id": "Q03267-1.182.182", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q03267-1.183.183", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q03267-1.184.184", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q03267-1.185.185", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q03267-1.186.186", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q03267-1.187.187", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q03267-1.188.188", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q03267-1.191.191", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q03267-1.192.192", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q03267-1.193.193", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q03267-1.195.195", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03267-1.191.191", "start_pos": 191, "end_pos": 191, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding.", "journal": "Genes & development", "date": "2000", "authors": "Cobb BS, Morales-Alcelay S, Kleiger G, Brown KE, Fisher AG, Smale ST", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "reference": [ { "type": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "L", "start_aa": "L", "up_seq": "PFKCHLCNYACRRRDALTGH", "down_seq": "RTHSVGKPHKCGYCGRSYKQ", "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "A", "comment": "No effect on pericentromeric heterochromatin location. Disrupted DNA binding.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "Q03267-1.173.173", "categories": [ "mutagenesis_flag" ] }, { "distance": 13, "direction": "downstream", "id": "Q03267-1.178.178", "categories": [ "mutagenesis_flag" ] }, { "distance": 12, "direction": "downstream", "id": "Q03267-1.179.179", "categories": [ "mutagenesis_flag" ] }, { "distance": 11, "direction": "downstream", "id": "Q03267-1.180.180", "categories": [ "mutagenesis_flag" ] }, { "distance": 10, "direction": "downstream", "id": "Q03267-1.181.181", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "downstream", "id": "Q03267-1.182.182", "categories": [ "mutagenesis_flag" ] }, { "distance": 8, "direction": "downstream", "id": "Q03267-1.183.183", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "downstream", "id": "Q03267-1.184.184", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q03267-1.185.185", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q03267-1.186.186", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q03267-1.187.187", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q03267-1.188.188", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q03267-1.189.189", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q03267-1.192.192", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q03267-1.193.193", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q03267-1.195.195", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03267-1.192.192", "start_pos": 192, "end_pos": 192, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding.", "journal": "Genes & development", "date": "2000", "authors": "Cobb BS, Morales-Alcelay S, Kleiger G, Brown KE, Fisher AG, Smale ST", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "reference": [ { "type": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "FKCHLCNYACRRRDALTGHL", "down_seq": "THSVGKPHKCGYCGRSYKQR", "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "No effect on pericentromeric heterochromatin location. No change in DNA binding.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "Q03267-1.173.173", "categories": [ "mutagenesis_flag" ] }, { "distance": 14, "direction": "downstream", "id": "Q03267-1.178.178", "categories": [ "mutagenesis_flag" ] }, { "distance": 13, "direction": "downstream", "id": "Q03267-1.179.179", "categories": [ "mutagenesis_flag" ] }, { "distance": 12, "direction": "downstream", "id": "Q03267-1.180.180", "categories": [ "mutagenesis_flag" ] }, { "distance": 11, "direction": "downstream", "id": "Q03267-1.181.181", "categories": [ "mutagenesis_flag" ] }, { "distance": 10, "direction": "downstream", "id": "Q03267-1.182.182", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "downstream", "id": "Q03267-1.183.183", "categories": [ "mutagenesis_flag" ] }, { "distance": 8, "direction": "downstream", "id": "Q03267-1.184.184", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "downstream", "id": "Q03267-1.185.185", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q03267-1.186.186", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q03267-1.187.187", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q03267-1.188.188", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q03267-1.189.189", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q03267-1.191.191", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q03267-1.193.193", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q03267-1.195.195", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03267-1.193.193", "start_pos": 193, "end_pos": 193, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding.", "journal": "Genes & development", "date": "2000", "authors": "Cobb BS, Morales-Alcelay S, Kleiger G, Brown KE, Fisher AG, Smale ST", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "reference": [ { "type": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "KCHLCNYACRRRDALTGHLR", "down_seq": "HSVGKPHKCGYCGRSYKQRS", "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "No effect on pericentromeric heterochromatin location. No change in DNA binding.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "10970879", "url": "https://glygen.org/publication/PubMed/10970879" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "Q03267-1.173.173", "categories": [ "mutagenesis_flag" ] }, { "distance": 15, "direction": "downstream", "id": "Q03267-1.178.178", "categories": [ "mutagenesis_flag" ] }, { "distance": 14, "direction": "downstream", "id": "Q03267-1.179.179", "categories": [ "mutagenesis_flag" ] }, { "distance": 13, "direction": "downstream", "id": "Q03267-1.180.180", "categories": [ "mutagenesis_flag" ] }, { "distance": 12, "direction": "downstream", "id": "Q03267-1.181.181", "categories": [ "mutagenesis_flag" ] }, { "distance": 11, "direction": "downstream", "id": "Q03267-1.182.182", "categories": [ "mutagenesis_flag" ] }, { "distance": 10, "direction": "downstream", "id": "Q03267-1.183.183", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "downstream", "id": "Q03267-1.184.184", "categories": [ "mutagenesis_flag" ] }, { "distance": 8, "direction": "downstream", "id": "Q03267-1.185.185", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "downstream", "id": "Q03267-1.186.186", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q03267-1.187.187", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q03267-1.188.188", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q03267-1.189.189", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q03267-1.191.191", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q03267-1.192.192", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q03267-1.195.195", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03267-1.195.195", "start_pos": 195, "end_pos": 195, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A common mechanism for mitotic inactivation of C2H2 zinc finger DNA-binding domains.", "journal": "Genes & development", "date": "2002", "authors": "Dovat S, Ronni T, Russell D, Ferrini R, Cobb BS, Smale ST", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "iPTMnet", "id": "Q03267", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03267" } ], "reference": [ { "type": "PubMed", "id": "12464629", "url": "https://glygen.org/publication/PubMed/12464629" } ] } ], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "12464629", "url": "https://glygen.org/publication/PubMed/12464629", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q03267", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03267", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "HLCNYACRRRDALTGHLRTH", "down_seq": "VGKPHKCGYCGRSYKQRSSL", "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Abolishes phosphorylation, no effect on DNA binding nor on pericentromeric location. Loss of DNA binding and pericentromeric location; when associated with A-140 and A-167.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "12464629", "url": "https://glygen.org/publication/PubMed/12464629" } ] }, { "sequence_org": "S", "sequence_mut": "D", "comment": "Abolishes phosphorylation, no effect on DNA binding nor on pericentromeric location. Loss of DNA binding and pericentromeric location; when associated with E-140 and E-167.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "12464629", "url": "https://glygen.org/publication/PubMed/12464629" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "12464629", "url": "https://glygen.org/publication/PubMed/12464629" }, { "database": "iPTMnet", "id": "Q03267", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03267" } ], "site_lbl": "Ser195" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "mutagenesis_flag", "phosphorylation_flag" ], "glycosylation": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "Q03267-1.178.178", "categories": [ "mutagenesis_flag" ] }, { "distance": 16, "direction": "downstream", "id": "Q03267-1.179.179", "categories": [ "mutagenesis_flag" ] }, { "distance": 15, "direction": "downstream", "id": "Q03267-1.180.180", "categories": [ "mutagenesis_flag" ] }, { "distance": 14, "direction": "downstream", "id": "Q03267-1.181.181", "categories": [ "mutagenesis_flag" ] }, { "distance": 13, "direction": "downstream", "id": "Q03267-1.182.182", "categories": [ "mutagenesis_flag" ] }, { "distance": 12, "direction": "downstream", "id": "Q03267-1.183.183", "categories": [ "mutagenesis_flag" ] }, { "distance": 11, "direction": "downstream", "id": "Q03267-1.184.184", "categories": [ "mutagenesis_flag" ] }, { "distance": 10, "direction": "downstream", "id": "Q03267-1.185.185", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "downstream", "id": "Q03267-1.186.186", "categories": [ "mutagenesis_flag" ] }, { "distance": 8, "direction": "downstream", "id": "Q03267-1.187.187", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "downstream", "id": "Q03267-1.188.188", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q03267-1.189.189", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q03267-1.191.191", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q03267-1.192.192", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q03267-1.193.193", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03267-1.239.239", "start_pos": 239, "end_pos": 239, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Ikaros SUMOylation: switching out of repression.", "journal": "Molecular and cellular biology", "date": "2005", "authors": "Gomez-del Arco P, Koipally J, Georgopoulos K", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "reference": [ { "type": "PubMed", "id": "15767674", "url": "https://glygen.org/publication/PubMed/15767674" } ] } ], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "15767674", "url": "https://glygen.org/publication/PubMed/15767674", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "KERCHNYLESMGLPGVCPVI", "down_seq": "EETNHNEMAEDLCKIGAERS", "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "R", "comment": "Some loss of sumoylation. Complete loss of sumoylation, increased repressor activity but no change in pericentromeric heterochromatin location.; when associated with R-58 and R-459.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "15767674", "url": "https://glygen.org/publication/PubMed/15767674" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "upstream", "id": "Q03267-1.259.259", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03267-1.23.23", "start_pos": 23, "end_pos": 23, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Recruitment of ikaros to pericentromeric heterochromatin is regulated by phosphorylation.", "journal": "The Journal of biological chemistry", "date": "2008", "authors": "Gurel Z, Ronni T, Ho S, Kuchar J, Payne KJ, Turk CW, Dovat S", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "iPTMnet", "id": "Q03267", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03267" } ], "reference": [ { "type": "PubMed", "id": "18223295", "url": "https://glygen.org/publication/PubMed/18223295" } ] } ], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18223295", "url": "https://glygen.org/publication/PubMed/18223295", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q03267", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03267", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "VDEGQDMSQVSGKESPPVSD", "down_seq": "PDEGDEPMPVPEDLSTTSGA", "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Abolishes phosphorylation. No change in binding to gamma satellites A and B. No change in pericentromeric location.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "18223295", "url": "https://glygen.org/publication/PubMed/18223295" } ] }, { "sequence_org": "T", "sequence_mut": "D", "comment": "Decreased binding to gamma satellites A and B by 3-fold. Little change in pericentromeric location.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "18223295", "url": "https://glygen.org/publication/PubMed/18223295" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "18223295", "url": "https://glygen.org/publication/PubMed/18223295" }, { "database": "iPTMnet", "id": "Q03267", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03267" } ], "site_lbl": "Thr23" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "mutagenesis_flag", "phosphorylation_flag" ], "glycosylation": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "Q03267-1.13.13", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03267-1.293.293", "start_pos": 293, "end_pos": 293, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Recruitment of ikaros to pericentromeric heterochromatin is regulated by phosphorylation.", "journal": "The Journal of biological chemistry", "date": "2008", "authors": "Gurel Z, Ronni T, Ho S, Kuchar J, Payne KJ, Turk CW, Dovat S", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "iPTMnet", "id": "Q03267", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03267" } ], "reference": [ { "type": "PubMed", "id": "18223295", "url": "https://glygen.org/publication/PubMed/18223295" } ] } ], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18223295", "url": "https://glygen.org/publication/PubMed/18223295", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q03267", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03267", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KSSMPQKFLGDKCLSDMPYD", "down_seq": "ANYEKEDMMTSHVMDQAINN", "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Abolishes phosphorylation. No change in binding to gamma satellites A and B. No change in pericentromeric location. Increased DNA binding affinity toward TDT.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "18223295", "url": "https://glygen.org/publication/PubMed/18223295" } ] }, { "sequence_org": "S", "sequence_mut": "D", "comment": "Decreased binding to gamma satellite A by 5-fold and to gamma satellite B by 3-fold. Diffuse nuclear location. Decreased DNA binding affinity toward TdT by 3-fold.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "18223295", "url": "https://glygen.org/publication/PubMed/18223295" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "18223295", "url": "https://glygen.org/publication/PubMed/18223295" }, { "database": "iPTMnet", "id": "Q03267", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03267" } ], "site_lbl": "Ser293" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "mutagenesis_flag", "phosphorylation_flag" ], "glycosylation": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "Q03267-1.287.287", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03267-1.384.384", "start_pos": 384, "end_pos": 384, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Phosphorylation controls Ikaros's ability to negatively regulate the G(1)-S transition.", "journal": "Molecular and cellular biology", "date": "2004", "authors": "Gomez-del Arco P, Maki K, Georgopoulos K", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "iPTMnet", "id": "Q03267", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03267" } ], "reference": [ { "type": "PubMed", "id": "15024069", "url": "https://glygen.org/publication/PubMed/15024069" } ] } ], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "15024069", "url": "https://glygen.org/publication/PubMed/15024069", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q03267", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03267", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AVDNLLLLSKAKSVSSEREA", "down_seq": "PSNSCQDSTDTESNAEEQRS", "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Significantly reduced phosphorylation and 2- to 3-fold increase in ability to arrest in G(1); when associated with A-386; A-388; A-392 and A-393. and A-392. Further reduction in phosphorylation; when associated with A-63; A-386; A-388; A-392 and A-393.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "15024069", "url": "https://glygen.org/publication/PubMed/15024069" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "15024069", "url": "https://glygen.org/publication/PubMed/15024069" }, { "database": "iPTMnet", "id": "Q03267", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03267" } ], "site_lbl": "Ser384" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "mutagenesis_flag", "phosphorylation_flag" ], "glycosylation": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "Q03267-1.386.386", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q03267-1.388.388", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q03267-1.392.392", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q03267-1.393.393", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q03267-1.397.397", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03267-1.386.386", "start_pos": 386, "end_pos": 386, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Phosphorylation controls Ikaros's ability to negatively regulate the G(1)-S transition.", "journal": "Molecular and cellular biology", "date": "2004", "authors": "Gomez-del Arco P, Maki K, Georgopoulos K", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "iPTMnet", "id": "Q03267", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03267" } ], "reference": [ { "type": "PubMed", "id": "15024069", "url": "https://glygen.org/publication/PubMed/15024069" } ] } ], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "15024069", "url": "https://glygen.org/publication/PubMed/15024069", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q03267", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03267", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DNLLLLSKAKSVSSEREASP", "down_seq": "NSCQDSTDTESNAEEQRSGL", "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Significantly reduced phosphorylation and 2- to 3-fold increase in ability to arrest in G(1); when associated with A-384; A-388; A-392 and A-393. Further reduction in phosphorylation; when associated with A-63; A-384; A-388; A-392 and A-393.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "15024069", "url": "https://glygen.org/publication/PubMed/15024069" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "15024069", "url": "https://glygen.org/publication/PubMed/15024069" }, { "database": "iPTMnet", "id": "Q03267", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03267" } ], "site_lbl": "Ser386" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "mutagenesis_flag", "phosphorylation_flag" ], "glycosylation": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "Q03267-1.384.384", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q03267-1.388.388", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q03267-1.392.392", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q03267-1.393.393", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q03267-1.397.397", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03267-1.388.388", "start_pos": 388, "end_pos": 388, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Phosphorylation controls Ikaros's ability to negatively regulate the G(1)-S transition.", "journal": "Molecular and cellular biology", "date": "2004", "authors": "Gomez-del Arco P, Maki K, Georgopoulos K", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "iPTMnet", "id": "Q03267", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03267" } ], "reference": [ { "type": "PubMed", "id": "15024069", "url": "https://glygen.org/publication/PubMed/15024069" } ] } ], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "15024069", "url": "https://glygen.org/publication/PubMed/15024069", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q03267", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03267", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LLLLSKAKSVSSEREASPSN", "down_seq": "CQDSTDTESNAEEQRSGLIY", "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Significantly reduced phosphorylation and 2- to 3-fold increase in ability to arrest in G(1); when associated with A-384; A-386; A-392 and A-393. Further reduction in phosphorylation; when associated with A-63; A-384; A-386; A-392 and A-393.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "15024069", "url": "https://glygen.org/publication/PubMed/15024069" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "15024069", "url": "https://glygen.org/publication/PubMed/15024069" }, { "database": "iPTMnet", "id": "Q03267", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03267" } ], "site_lbl": "Ser388" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "mutagenesis_flag", "phosphorylation_flag" ], "glycosylation": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "Q03267-1.384.384", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q03267-1.386.386", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q03267-1.392.392", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q03267-1.393.393", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q03267-1.397.397", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03267-1.392.392", "start_pos": 392, "end_pos": 392, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Phosphorylation controls Ikaros's ability to negatively regulate the G(1)-S transition.", "journal": "Molecular and cellular biology", "date": "2004", "authors": "Gomez-del Arco P, Maki K, Georgopoulos K", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "iPTMnet", "id": "Q03267", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03267" } ], "reference": [ { "type": "PubMed", "id": "15024069", "url": "https://glygen.org/publication/PubMed/15024069" } ] } ], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "15024069", "url": "https://glygen.org/publication/PubMed/15024069", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q03267", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03267", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SKAKSVSSEREASPSNSCQD", "down_seq": "TDTESNAEEQRSGLIYLTNH", "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Significantly reduced phosphorylation and 2- to 3-fold increase in ability to arrest in G(1); when associated with A-384; A-386; A-388 and A-392. Further reduction in phosphorylation; when associated with A-63; A-384; A-386; A-386 and A-388.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "15024069", "url": "https://glygen.org/publication/PubMed/15024069" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "15024069", "url": "https://glygen.org/publication/PubMed/15024069" }, { "database": "iPTMnet", "id": "Q03267", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03267" } ], "site_lbl": "Ser392" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "mutagenesis_flag", "phosphorylation_flag" ], "glycosylation": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "Q03267-1.384.384", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q03267-1.386.386", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q03267-1.388.388", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q03267-1.393.393", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q03267-1.397.397", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03267-1.393.393", "start_pos": 393, "end_pos": 393, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Phosphorylation controls Ikaros's ability to negatively regulate the G(1)-S transition.", "journal": "Molecular and cellular biology", "date": "2004", "authors": "Gomez-del Arco P, Maki K, Georgopoulos K", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "iPTMnet", "id": "Q03267", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03267" } ], "reference": [ { "type": "PubMed", "id": "15024069", "url": "https://glygen.org/publication/PubMed/15024069" } ] } ], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "15024069", "url": "https://glygen.org/publication/PubMed/15024069", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q03267", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03267", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "KAKSVSSEREASPSNSCQDS", "down_seq": "DTESNAEEQRSGLIYLTNHI", "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Significantly reduced phosphorylation and 2- to 3-fold increase in ability to arrest in G(1); when associated with A-384; A-386; A-388 and A-392. Further reduction in phosphorylation; when associated with A-63; A-384; A-386; A-388 and A-392.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "15024069", "url": "https://glygen.org/publication/PubMed/15024069" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "15024069", "url": "https://glygen.org/publication/PubMed/15024069" }, { "database": "iPTMnet", "id": "Q03267", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03267" } ], "site_lbl": "Thr393" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "mutagenesis_flag", "phosphorylation_flag" ], "glycosylation": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "Q03267-1.384.384", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "Q03267-1.386.386", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q03267-1.388.388", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q03267-1.392.392", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q03267-1.397.397", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03267-1.424.424", "start_pos": 424, "end_pos": 424, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Ikaros SUMOylation: switching out of repression.", "journal": "Molecular and cellular biology", "date": "2005", "authors": "Gomez-del Arco P, Koipally J, Georgopoulos K", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "reference": [ { "type": "PubMed", "id": "15767674", "url": "https://glygen.org/publication/PubMed/15767674" } ] } ], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "15767674", "url": "https://glygen.org/publication/PubMed/15767674", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "SGLIYLTNHINPHARNGLAL", "down_seq": "EEQRAYEVLRAASENSQDAF", "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "R", "comment": "No effect on sumoylation.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "15767674", "url": "https://glygen.org/publication/PubMed/15767674" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "upstream", "id": "Q03267-1.440.440", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03267-1.458.458", "start_pos": 458, "end_pos": 458, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Ikaros SUMOylation: switching out of repression.", "journal": "Molecular and cellular biology", "date": "2005", "authors": "Gomez-del Arco P, Koipally J, Georgopoulos K", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "reference": [ { "type": "PubMed", "id": "15767674", "url": "https://glygen.org/publication/PubMed/15767674" } ] } ], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "15767674", "url": "https://glygen.org/publication/PubMed/15767674", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "ENSQDAFRVVSTSGEQLKVY", "down_seq": "CEHCRVLFLDHVMYTIHMGC", "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "R", "comment": "No effect on sumoylation.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "15767674", "url": "https://glygen.org/publication/PubMed/15767674" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "Q03267-1.440.440", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q03267-1.465.467", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03267-1.465.467", "start_pos": 465, "end_pos": 467, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Ikaros stability and pericentromeric localization are regulated by protein phosphatase 1.", "journal": "The Journal of biological chemistry", "date": "2009", "authors": "Popescu M, Gurel Z, Ronni T, Song C, Hung KY, Payne KJ, Dovat S", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "reference": [ { "type": "PubMed", "id": "19282287", "url": "https://glygen.org/publication/PubMed/19282287" } ] } ], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19282287", "url": "https://glygen.org/publication/PubMed/19282287", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "LFL", "start_aa": "L", "up_seq": "RVVSTSGEQLKVYKCEHCRV", "down_seq": "DHVMYTIHMGCHGCHGFRDP", "mutagenesis": [ { "sequence_org": "LFL", "sequence_mut": "AFA", "comment": "Abolishes binding of PP1CC, decreases DNA binding, abolishes pericentromeric location, and results in IKAROS degradation.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "19282287", "url": "https://glygen.org/publication/PubMed/19282287" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "Q03267-1.458.458", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03267-1.58.58", "start_pos": 58, "end_pos": 58, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Ikaros SUMOylation: switching out of repression.", "journal": "Molecular and cellular biology", "date": "2005", "authors": "Gomez-del Arco P, Koipally J, Georgopoulos K", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "reference": [ { "type": "PubMed", "id": "15767674", "url": "https://glygen.org/publication/PubMed/15767674" } ] } ], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "15767674", "url": "https://glygen.org/publication/PubMed/15767674", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "STTSGAQQNSKSDRGMGSNV", "down_seq": "VETQSDEENGRACEMNGEEC", "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "R", "comment": "Some loss of sumoylation. Complete loss of sumoylation, increased repressor activity but no change in pericentromeric heterochromatin location; when associated with R-240 and R-459.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "15767674", "url": "https://glygen.org/publication/PubMed/15767674" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "upstream", "id": "Q03267-1.63.63", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03267-1.63.63", "start_pos": 63, "end_pos": 63, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Phosphorylation controls Ikaros's ability to negatively regulate the G(1)-S transition.", "journal": "Molecular and cellular biology", "date": "2004", "authors": "Gomez-del Arco P, Maki K, Georgopoulos K", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "iPTMnet", "id": "Q03267", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03267" } ], "reference": [ { "type": "PubMed", "id": "15024069", "url": "https://glygen.org/publication/PubMed/15024069" } ] }, { "title": "Recruitment of ikaros to pericentromeric heterochromatin is regulated by phosphorylation.", "journal": "The Journal of biological chemistry", "date": "2008", "authors": "Gurel Z, Ronni T, Ho S, Kuchar J, Payne KJ, Turk CW, Dovat S", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "iPTMnet", "id": "Q03267", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03267" } ], "reference": [ { "type": "PubMed", "id": "18223295", "url": "https://glygen.org/publication/PubMed/18223295" } ] }, { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "iPTMnet", "id": "Q03267", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03267" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "15024069", "url": "https://glygen.org/publication/PubMed/15024069", "database": "PubMed", "categories": [ "Other" ] }, { "id": "18223295", "url": "https://glygen.org/publication/PubMed/18223295", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q03267", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03267", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AQQNSKSDRGMGSNVKVETQ", "down_seq": "DEENGRACEMNGEECAEDLR", "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "No change in pericentromeric location. Greatly reduced phosphorylation; when associated with A-384; A-386; A-388; A392 and A-393. No effect on DNA-binding activity. Increased DNA-binding activity; when associated with A-384; A-386; A-388; A-392 and A-393.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "15024069", "url": "https://glygen.org/publication/PubMed/15024069" }, { "database": "PubMed", "id": "18223295", "url": "https://glygen.org/publication/PubMed/18223295" } ] }, { "sequence_org": "S", "sequence_mut": "D", "comment": "No change in binding to gamma satellites A and B. No change in pericentromeric location.", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "15024069", "url": "https://glygen.org/publication/PubMed/15024069" }, { "database": "PubMed", "id": "18223295", "url": "https://glygen.org/publication/PubMed/18223295" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "PubMed", "id": "15024069", "url": "https://glygen.org/publication/PubMed/15024069" }, { "database": "PubMed", "id": "18223295", "url": "https://glygen.org/publication/PubMed/18223295" }, { "database": "iPTMnet", "id": "Q03267", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03267" } ], "site_lbl": "Ser63" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "mutagenesis_flag", "phosphorylation_flag" ], "glycosylation": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "Q03267-1.58.58", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03267-1.259.259", "start_pos": 259, "end_pos": 259, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KEETNHNEMAEDLCKIGAER", "down_seq": "LVLDRLASNVAKRKSSMPQK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "site_lbl": "Ser259" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "Q03267-1.239.239", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q03267-1.287.287", "start_pos": 287, "end_pos": 287, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SNVAKRKSSMPQKFLGDKCL", "down_seq": "DMPYDSANYEKEDMMTSHVM", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "site_lbl": "Ser287" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "upstream", "id": "Q03267-1.293.293", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q03267-1.357.357", "start_pos": 357, "end_pos": 357, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VPVISSMYQLHKPPSDGPPR", "down_seq": "NHSAQDAVDNLLLLSKAKSV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "site_lbl": "Ser357" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "Q03267-1.360.360", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q03267-1.360.360", "start_pos": 360, "end_pos": 360, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ISSMYQLHKPPSDGPPRSNH", "down_seq": "AQDAVDNLLLLSKAKSVSSE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "site_lbl": "Ser360" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "Q03267-1.357.357", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q03267-1.397.397", "start_pos": 397, "end_pos": 397, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "iPTMnet", "id": "Q03267", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03267" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q03267", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03267", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VSSEREASPSNSCQDSTDTE", "down_seq": "NAEEQRSGLIYLTNHINPHA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q03267", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03267" } ], "site_lbl": "Ser397" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "Q03267-1.384.384", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "Q03267-1.386.386", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "Q03267-1.388.388", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q03267-1.392.392", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q03267-1.393.393", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03267-1.440.440", "start_pos": 440, "end_pos": 440, "uniprot_canonical_ac": "Q03267-1", "length": 517, "uniprot_id": "IKZF1_MOUSE", "protein_name": "DNA-binding protein Ikaros", "refseq_ac": "", "refseq_name": "", "gene_name": "Ikzf1", "gene_names_uniprotkb": "Ikzf1; Ikaros; Lyf1; Zfpn1a1; Znfn1a1", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "iPTMnet", "id": "Q03267", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03267" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q03267", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03267", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GLALKEEQRAYEVLRAASEN", "down_seq": "QDAFRVVSTSGEQLKVYKCE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q03267", "url": "https://www.uniprot.org/uniprotkb/Q03267" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q03267", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03267" } ], "site_lbl": "Ser440" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "157", "end_pos": "157" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "189", "end_pos": "189" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "465", "end_pos": "467" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "63", "end_pos": "63" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "Q03267-1.424.424", "categories": [ "mutagenesis_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q03267-1.458.458", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8C735-1.304.304", "start_pos": 304, "end_pos": 304, "uniprot_canonical_ac": "Q8C735-1", "length": 542, "uniprot_id": "LIN9_MOUSE", "protein_name": "Protein lin-9 homolog", "refseq_ac": "NP_001096652", "refseq_name": "protein lin-9 homolog", "gene_name": "Lin9", "gene_names_uniprotkb": "Lin9; Bara; Tgs1", "gene_names_refseq": "2700022J23Rik; Bara; Lin-9; Lin9; TGS1; TGS; mLin-9", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8C735", "url": "https://www.uniprot.org/uniprotkb/Q8C735" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8C735", "url": "https://www.uniprot.org/uniprotkb/Q8C735" }, { "database": "iPTMnet", "id": "Q8C735", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8C735" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q8C735", "url": "https://www.uniprot.org/uniprotkb/Q8C735", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8C735", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8C735", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "AFGQKQRPSRFFMTPPRLHY", "down_seq": "PPLQSPITDGDPLLGQSPWR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q8C735", "url": "https://www.uniprot.org/uniprotkb/Q8C735" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q8C735", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8C735" } ], "site_lbl": "Thr304" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "304", "end_pos": "304" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "65", "end_pos": "65" }, { "start_pos": "95", "end_pos": "95" }, { "start_pos": "96", "end_pos": "96" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "upstream", "id": "Q8C735-1.309.309", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "Q8C735-1.321.321", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8C735-1.309.309", "start_pos": 309, "end_pos": 309, "uniprot_canonical_ac": "Q8C735-1", "length": 542, "uniprot_id": "LIN9_MOUSE", "protein_name": "Protein lin-9 homolog", "refseq_ac": "NP_001096652", "refseq_name": "protein lin-9 homolog", "gene_name": "Lin9", "gene_names_uniprotkb": "Lin9; Bara; Tgs1", "gene_names_refseq": "2700022J23Rik; Bara; Lin-9; Lin9; TGS1; TGS; mLin-9", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8C735", "url": "https://www.uniprot.org/uniprotkb/Q8C735" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8C735", "url": "https://www.uniprot.org/uniprotkb/Q8C735" }, { "database": "iPTMnet", "id": "Q8C735", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8C735" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q8C735", "url": "https://www.uniprot.org/uniprotkb/Q8C735", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8C735", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8C735", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QRPSRFFMTPPRLHYTPPLQ", "down_seq": "PITDGDPLLGQSPWRSKVSG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8C735", "url": "https://www.uniprot.org/uniprotkb/Q8C735" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q8C735", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8C735" } ], "site_lbl": "Ser309" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "304", "end_pos": "304" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "65", "end_pos": "65" }, { "start_pos": "95", "end_pos": "95" }, { "start_pos": "96", "end_pos": "96" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "Q8C735-1.304.304", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "Q8C735-1.321.321", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8C735-1.321.321", "start_pos": 321, "end_pos": 321, "uniprot_canonical_ac": "Q8C735-1", "length": 542, "uniprot_id": "LIN9_MOUSE", "protein_name": "Protein lin-9 homolog", "refseq_ac": "NP_001096652", "refseq_name": "protein lin-9 homolog", "gene_name": "Lin9", "gene_names_uniprotkb": "Lin9; Bara; Tgs1", "gene_names_refseq": "2700022J23Rik; Bara; Lin-9; Lin9; TGS1; TGS; mLin-9", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8C735", "url": "https://www.uniprot.org/uniprotkb/Q8C735" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8C735", "url": "https://www.uniprot.org/uniprotkb/Q8C735" }, { "database": "iPTMnet", "id": "Q8C735", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8C735" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q8C735", "url": "https://www.uniprot.org/uniprotkb/Q8C735", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8C735", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8C735", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LHYTPPLQSPITDGDPLLGQ", "down_seq": "PWRSKVSGSDTETLGGFPVE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8C735", "url": "https://www.uniprot.org/uniprotkb/Q8C735" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q8C735", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8C735" } ], "site_lbl": "Ser321" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "304", "end_pos": "304" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "65", "end_pos": "65" }, { "start_pos": "95", "end_pos": "95" }, { "start_pos": "96", "end_pos": "96" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "Q8C735-1.304.304", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "Q8C735-1.309.309", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8C735-1.65.65", "start_pos": 65, "end_pos": 65, "uniprot_canonical_ac": "Q8C735-1", "length": 542, "uniprot_id": "LIN9_MOUSE", "protein_name": "Protein lin-9 homolog", "refseq_ac": "NP_001096652", "refseq_name": "protein lin-9 homolog", "gene_name": "Lin9", "gene_names_uniprotkb": "Lin9; Bara; Tgs1", "gene_names_refseq": "2700022J23Rik; Bara; Lin-9; Lin9; TGS1; TGS; mLin-9", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8C735", "url": "https://www.uniprot.org/uniprotkb/Q8C735" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8C735", "url": "https://www.uniprot.org/uniprotkb/Q8C735", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RNAGPAVEMPFRNSKRSRLF", "down_seq": "DEDDRQINTKSPKRNQRVAM", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8C735", "url": "https://www.uniprot.org/uniprotkb/Q8C735" } ], "site_lbl": "Ser65" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "304", "end_pos": "304" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "65", "end_pos": "65" }, { "start_pos": "95", "end_pos": "95" }, { "start_pos": "96", "end_pos": "96" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8C735-1.95.95", "start_pos": 95, "end_pos": 95, "uniprot_canonical_ac": "Q8C735-1", "length": 542, "uniprot_id": "LIN9_MOUSE", "protein_name": "Protein lin-9 homolog", "refseq_ac": "NP_001096652", "refseq_name": "protein lin-9 homolog", "gene_name": "Lin9", "gene_names_uniprotkb": "Lin9; Bara; Tgs1", "gene_names_refseq": "2700022J23Rik; Bara; Lin-9; Lin9; TGS1; TGS; mLin-9", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8C735", "url": "https://www.uniprot.org/uniprotkb/Q8C735" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8C735", "url": "https://www.uniprot.org/uniprotkb/Q8C735" }, { "database": "iPTMnet", "id": "Q8C735", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8C735" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q8C735", "url": "https://www.uniprot.org/uniprotkb/Q8C735", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8C735", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8C735", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KSPKRNQRVAMIPQKFTATM", "down_seq": "TPDKKASQKIGFRLRNLLKL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8C735", "url": "https://www.uniprot.org/uniprotkb/Q8C735" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q8C735", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8C735" } ], "site_lbl": "Ser95" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "304", "end_pos": "304" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "65", "end_pos": "65" }, { "start_pos": "95", "end_pos": "95" }, { "start_pos": "96", "end_pos": "96" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "Q8C735-1.96.96", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8C735-1.96.96", "start_pos": 96, "end_pos": 96, "uniprot_canonical_ac": "Q8C735-1", "length": 542, "uniprot_id": "LIN9_MOUSE", "protein_name": "Protein lin-9 homolog", "refseq_ac": "NP_001096652", "refseq_name": "protein lin-9 homolog", "gene_name": "Lin9", "gene_names_uniprotkb": "Lin9; Bara; Tgs1", "gene_names_refseq": "2700022J23Rik; Bara; Lin-9; Lin9; TGS1; TGS; mLin-9", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8C735", "url": "https://www.uniprot.org/uniprotkb/Q8C735" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8C735", "url": "https://www.uniprot.org/uniprotkb/Q8C735", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "SPKRNQRVAMIPQKFTATMS", "down_seq": "PDKKASQKIGFRLRNLLKLP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q8C735", "url": "https://www.uniprot.org/uniprotkb/Q8C735" } ], "site_lbl": "Thr96" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "304", "end_pos": "304" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "65", "end_pos": "65" }, { "start_pos": "95", "end_pos": "95" }, { "start_pos": "96", "end_pos": "96" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "Q8C735-1.95.95", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8VD75-1.338.338", "start_pos": 338, "end_pos": 338, "uniprot_canonical_ac": "Q8VD75-1", "length": 1029, "uniprot_id": "HIP1_MOUSE", "protein_name": "Huntingtin-interacting protein 1", "refseq_ac": "NP_666113", "refseq_name": "huntingtin-interacting protein 1 isoform 1", "gene_name": "Hip1", "gene_names_uniprotkb": "Hip1; Kiaa4113", "gene_names_refseq": "2610109B09Rik; A930014B11Rik; E130315I21Rik; Hip1; mKIAA4113", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VD75", "url": "https://www.uniprot.org/uniprotkb/Q8VD75" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8VD75", "url": "https://www.uniprot.org/uniprotkb/Q8VD75", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VSSPDSEPVLEKDDLMDMDA", "down_seq": "QQTLFDNKFDDVFGSSLSSD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8VD75", "url": "https://www.uniprot.org/uniprotkb/Q8VD75" } ], "site_lbl": "Ser338" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "338", "end_pos": "338" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "A2AAE1-1.1899.1899", "start_pos": 1899, "end_pos": 1899, "uniprot_canonical_ac": "A2AAE1-1", "length": 5005, "uniprot_id": "BLTP1_MOUSE", "protein_name": "Bridge-like lipid transfer protein family member 1", "refseq_ac": "NP_766267", "refseq_name": "bridge-like lipid transfer protein family member 1", "gene_name": "Bltp1", "gene_names_uniprotkb": "Bltp1; 4932438A13Rik; Fsa; Kiaa1109; Kiaa1371", "gene_names_refseq": "4732443H21; 4932438A13Rik; B830039D19Rik; Bltp1; D630029K19Rik; FSA; Kiaa1109; Tweek", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "TRIGPSQEKWGWIMFECGLE", "down_seq": "LTIKGGRQSGAVLYNSFGIM", "glycosylation": [ { "glytoucan_ac": "G34071NT", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "LENLTLK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1899", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1899", "end_pos": "1899" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "2555", "end_pos": "2555" }, { "start_pos": "2605", "end_pos": "2605" }, { "start_pos": "4418", "end_pos": "4418" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2414", "end_pos": "2414" }, { "start_pos": "2605", "end_pos": "2605" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1301", "end_pos": "1301" }, { "start_pos": "1305", "end_pos": "1305" }, { "start_pos": "1323", "end_pos": "1323" }, { "start_pos": "1325", "end_pos": "1325" }, { "start_pos": "1355", "end_pos": "1355" }, { "start_pos": "1406", "end_pos": "1406" }, { "start_pos": "1805", "end_pos": "1805" }, { "start_pos": "1808", "end_pos": "1808" }, { "start_pos": "2601", "end_pos": "2601" }, { "start_pos": "2603", "end_pos": "2603" }, { "start_pos": "2755", "end_pos": "2755" }, { "start_pos": "3562", "end_pos": "3562" }, { "start_pos": "3653", "end_pos": "3653" }, { "start_pos": "4124", "end_pos": "4124" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "A2AAE1-1.206.206", "start_pos": 206, "end_pos": 206, "uniprot_canonical_ac": "A2AAE1-1", "length": 5005, "uniprot_id": "BLTP1_MOUSE", "protein_name": "Bridge-like lipid transfer protein family member 1", "refseq_ac": "NP_766267", "refseq_name": "bridge-like lipid transfer protein family member 1", "gene_name": "Bltp1", "gene_names_uniprotkb": "Bltp1; 4932438A13Rik; Fsa; Kiaa1109; Kiaa1371", "gene_names_refseq": "4732443H21; 4932438A13Rik; B830039D19Rik; Bltp1; D630029K19Rik; FSA; Kiaa1109; Tweek", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "KTESQDPTSSWRSLIPVIKV", "down_seq": "VSTGRLAFGNHYQPQTLCIN", "glycosylation": [ { "glytoucan_ac": "G27058EU", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "VNVSTGR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn206", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1899", "end_pos": "1899" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "2555", "end_pos": "2555" }, { "start_pos": "2605", "end_pos": "2605" }, { "start_pos": "4418", "end_pos": "4418" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2414", "end_pos": "2414" }, { "start_pos": "2605", "end_pos": "2605" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1301", "end_pos": "1301" }, { "start_pos": "1305", "end_pos": "1305" }, { "start_pos": "1323", "end_pos": "1323" }, { "start_pos": "1325", "end_pos": "1325" }, { "start_pos": "1355", "end_pos": "1355" }, { "start_pos": "1406", "end_pos": "1406" }, { "start_pos": "1805", "end_pos": "1805" }, { "start_pos": "1808", "end_pos": "1808" }, { "start_pos": "2601", "end_pos": "2601" }, { "start_pos": "2603", "end_pos": "2603" }, { "start_pos": "2755", "end_pos": "2755" }, { "start_pos": "3562", "end_pos": "3562" }, { "start_pos": "3653", "end_pos": "3653" }, { "start_pos": "4124", "end_pos": "4124" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "A2AAE1-1.2555.2555", "start_pos": 2555, "end_pos": 2555, "uniprot_canonical_ac": "A2AAE1-1", "length": 5005, "uniprot_id": "BLTP1_MOUSE", "protein_name": "Bridge-like lipid transfer protein family member 1", "refseq_ac": "NP_766267", "refseq_name": "bridge-like lipid transfer protein family member 1", "gene_name": "Bltp1", "gene_names_uniprotkb": "Bltp1; 4932438A13Rik; Fsa; Kiaa1109; Kiaa1371", "gene_names_refseq": "4732443H21; 4932438A13Rik; B830039D19Rik; Bltp1; D630029K19Rik; FSA; Kiaa1109; Tweek", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "STSALSFHDLNKRYYNTFHC", "down_seq": "FTISCQSISQHVDMALVRLI", "glycosylation": [ { "glytoucan_ac": "G62765YT", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "YYNTFHCNFTISCQSISQHVDMALVR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn2555", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1899", "end_pos": "1899" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "2555", "end_pos": "2555" }, { "start_pos": "2605", "end_pos": "2605" }, { "start_pos": "4418", "end_pos": "4418" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2414", "end_pos": "2414" }, { "start_pos": "2605", "end_pos": "2605" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1301", "end_pos": "1301" }, { "start_pos": "1305", "end_pos": "1305" }, { "start_pos": "1323", "end_pos": "1323" }, { "start_pos": "1325", "end_pos": "1325" }, { "start_pos": "1355", "end_pos": "1355" }, { "start_pos": "1406", "end_pos": "1406" }, { "start_pos": "1805", "end_pos": "1805" }, { "start_pos": "1808", "end_pos": "1808" }, { "start_pos": "2601", "end_pos": "2601" }, { "start_pos": "2603", "end_pos": "2603" }, { "start_pos": "2755", "end_pos": "2755" }, { "start_pos": "3562", "end_pos": "3562" }, { "start_pos": "3653", "end_pos": "3653" }, { "start_pos": "4124", "end_pos": "4124" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "A2AAE1-1.2605.2605", "start_pos": 2605, "end_pos": 2605, "uniprot_canonical_ac": "A2AAE1-1", "length": 5005, "uniprot_id": "BLTP1_MOUSE", "protein_name": "Bridge-like lipid transfer protein family member 1", "refseq_ac": "NP_766267", "refseq_name": "bridge-like lipid transfer protein family member 1", "gene_name": "Bltp1", "gene_names_uniprotkb": "Bltp1; 4932438A13Rik; Fsa; Kiaa1109; Kiaa1371", "gene_names_refseq": "4732443H21; 4932438A13Rik; B830039D19Rik; Bltp1; D630029K19Rik; FSA; Kiaa1109; Tweek", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "rs3388628625", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388628625", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "IKATQTDIKLSRYTAGSASP", "down_seq": "PTFKTRKHRDFRSSDFSRSS", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2605", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "snv": [ { "evidence": [ { "id": "rs3388628625", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388628625" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "T", "sequence_mut": "M", "comment": "Germline mutation passed 1 filters: o-glyco-site-loss (T->M).", "chr_id": "3", "chr_pos": "37041440", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "T2605", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1899", "end_pos": "1899" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "2555", "end_pos": "2555" }, { "start_pos": "2605", "end_pos": "2605" }, { "start_pos": "4418", "end_pos": "4418" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2414", "end_pos": "2414" }, { "start_pos": "2605", "end_pos": "2605" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1301", "end_pos": "1301" }, { "start_pos": "1305", "end_pos": "1305" }, { "start_pos": "1323", "end_pos": "1323" }, { "start_pos": "1325", "end_pos": "1325" }, { "start_pos": "1355", "end_pos": "1355" }, { "start_pos": "1406", "end_pos": "1406" }, { "start_pos": "1805", "end_pos": "1805" }, { "start_pos": "1808", "end_pos": "1808" }, { "start_pos": "2601", "end_pos": "2601" }, { "start_pos": "2603", "end_pos": "2603" }, { "start_pos": "2755", "end_pos": "2755" }, { "start_pos": "3562", "end_pos": "3562" }, { "start_pos": "3653", "end_pos": "3653" }, { "start_pos": "4124", "end_pos": "4124" } ] } ], "categories": [ "glycosylation_flag", "snv_flag" ], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "A2AAE1-1.2601.2601", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "A2AAE1-1.2603.2603", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "A2AAE1-1.4418.4418", "start_pos": 4418, "end_pos": 4418, "uniprot_canonical_ac": "A2AAE1-1", "length": 5005, "uniprot_id": "BLTP1_MOUSE", "protein_name": "Bridge-like lipid transfer protein family member 1", "refseq_ac": "NP_766267", "refseq_name": "bridge-like lipid transfer protein family member 1", "gene_name": "Bltp1", "gene_names_uniprotkb": "Bltp1; 4932438A13Rik; Fsa; Kiaa1109; Kiaa1371", "gene_names_refseq": "4732443H21; 4932438A13Rik; B830039D19Rik; Bltp1; D630029K19Rik; FSA; Kiaa1109; Tweek", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "TPWETLVVFAINLKQLNVQM", "down_seq": "MSNVMGNTTWTTSGLKSQGR", "glycosylation": [ { "glytoucan_ac": "G92050GC", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "QLNVQMNMSNVMGNTTWTTSGLK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn4418", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1899", "end_pos": "1899" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "2555", "end_pos": "2555" }, { "start_pos": "2605", "end_pos": "2605" }, { "start_pos": "4418", "end_pos": "4418" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2414", "end_pos": "2414" }, { "start_pos": "2605", "end_pos": "2605" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1301", "end_pos": "1301" }, { "start_pos": "1305", "end_pos": "1305" }, { "start_pos": "1323", "end_pos": "1323" }, { "start_pos": "1325", "end_pos": "1325" }, { "start_pos": "1355", "end_pos": "1355" }, { "start_pos": "1406", "end_pos": "1406" }, { "start_pos": "1805", "end_pos": "1805" }, { "start_pos": "1808", "end_pos": "1808" }, { "start_pos": "2601", "end_pos": "2601" }, { "start_pos": "2603", "end_pos": "2603" }, { "start_pos": "2755", "end_pos": "2755" }, { "start_pos": "3562", "end_pos": "3562" }, { "start_pos": "3653", "end_pos": "3653" }, { "start_pos": "4124", "end_pos": "4124" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "A2AAE1-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "A2AAE1-1", "length": 5005, "uniprot_id": "BLTP1_MOUSE", "protein_name": "Bridge-like lipid transfer protein family member 1", "refseq_ac": "NP_766267", "refseq_name": "bridge-like lipid transfer protein family member 1", "gene_name": "Bltp1", "gene_names_uniprotkb": "Bltp1; 4932438A13Rik; Fsa; Kiaa1109; Kiaa1371", "gene_names_refseq": "4732443H21; 4932438A13Rik; B830039D19Rik; Bltp1; D630029K19Rik; FSA; Kiaa1109; Tweek", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation is required for B cell homeostasis and antibody responses.", "journal": "Nature communications", "date": "2017", "authors": "Wu JL, Chiang MF, Hsu PH, Tsai DY, Hung KH, Wang YH, Angata T, Lin KI", "evidence": [ { "database": "O-GlcNAc Database", "id": "A2AAE1", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A2AAE1" } ], "reference": [ { "type": "PubMed", "id": "29187734", "url": "https://glygen.org/publication/PubMed/29187734" } ] } ], "crossref": [ { "id": "29187734", "url": "https://glygen.org/publication/PubMed/29187734", "database": "PubMed", "categories": [ "Other" ] }, { "id": "A2AAE1", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A2AAE1", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "29187734", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29187734" }, { "id": "A2AAE1", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A2AAE1" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1899", "end_pos": "1899" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "2555", "end_pos": "2555" }, { "start_pos": "2605", "end_pos": "2605" }, { "start_pos": "4418", "end_pos": "4418" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2414", "end_pos": "2414" }, { "start_pos": "2605", "end_pos": "2605" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1301", "end_pos": "1301" }, { "start_pos": "1305", "end_pos": "1305" }, { "start_pos": "1323", "end_pos": "1323" }, { "start_pos": "1325", "end_pos": "1325" }, { "start_pos": "1355", "end_pos": "1355" }, { "start_pos": "1406", "end_pos": "1406" }, { "start_pos": "1805", "end_pos": "1805" }, { "start_pos": "1808", "end_pos": "1808" }, { "start_pos": "2601", "end_pos": "2601" }, { "start_pos": "2603", "end_pos": "2603" }, { "start_pos": "2755", "end_pos": "2755" }, { "start_pos": "3562", "end_pos": "3562" }, { "start_pos": "3653", "end_pos": "3653" }, { "start_pos": "4124", "end_pos": "4124" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "A2AAE1-1.2414.2414", "start_pos": 2414, "end_pos": 2414, "uniprot_canonical_ac": "A2AAE1-1", "length": 5005, "uniprot_id": "BLTP1_MOUSE", "protein_name": "Bridge-like lipid transfer protein family member 1", "refseq_ac": "NP_766267", "refseq_name": "bridge-like lipid transfer protein family member 1", "gene_name": "Bltp1", "gene_names_uniprotkb": "Bltp1; 4932438A13Rik; Fsa; Kiaa1109; Kiaa1371", "gene_names_refseq": "4732443H21; 4932438A13Rik; B830039D19Rik; Bltp1; D630029K19Rik; FSA; Kiaa1109; Tweek", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388620952", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388620952", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DFNTVLSSDQNTLDGTHSQH", "down_seq": "TSQDDVAGVEEANQGFPAVQ", "snv": [ { "evidence": [ { "id": "rs3388620952", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388620952" } ], "glycoeffect": [ "n-glyco-sequon-gain", "o-glyco-site-loss" ], "sequence_org": "S", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (STS->NTS).", "chr_id": "3", "chr_pos": "37029835", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S2414", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1899", "end_pos": "1899" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "2555", "end_pos": "2555" }, { "start_pos": "2605", "end_pos": "2605" }, { "start_pos": "4418", "end_pos": "4418" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2414", "end_pos": "2414" }, { "start_pos": "2605", "end_pos": "2605" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1301", "end_pos": "1301" }, { "start_pos": "1305", "end_pos": "1305" }, { "start_pos": "1323", "end_pos": "1323" }, { "start_pos": "1325", "end_pos": "1325" }, { "start_pos": "1355", "end_pos": "1355" }, { "start_pos": "1406", "end_pos": "1406" }, { "start_pos": "1805", "end_pos": "1805" }, { "start_pos": "1808", "end_pos": "1808" }, { "start_pos": "2601", "end_pos": "2601" }, { "start_pos": "2603", "end_pos": "2603" }, { "start_pos": "2755", "end_pos": "2755" }, { "start_pos": "3562", "end_pos": "3562" }, { "start_pos": "3653", "end_pos": "3653" }, { "start_pos": "4124", "end_pos": "4124" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "A2AAE1-1.1301.1301", "start_pos": 1301, "end_pos": 1301, "uniprot_canonical_ac": "A2AAE1-1", "length": 5005, "uniprot_id": "BLTP1_MOUSE", "protein_name": "Bridge-like lipid transfer protein family member 1", "refseq_ac": "NP_766267", "refseq_name": "bridge-like lipid transfer protein family member 1", "gene_name": "Bltp1", "gene_names_uniprotkb": "Bltp1; 4932438A13Rik; Fsa; Kiaa1109; Kiaa1371", "gene_names_refseq": "4732443H21; 4932438A13Rik; B830039D19Rik; Bltp1; D630029K19Rik; FSA; Kiaa1109; Tweek", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TEISGTSPVSPNTQDKSVGQ", "down_seq": "PLRSPLKRQASVCSTRLGST", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1" } ], "site_lbl": "Ser1301" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1899", "end_pos": "1899" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "2555", "end_pos": "2555" }, { "start_pos": "2605", "end_pos": "2605" }, { "start_pos": "4418", "end_pos": "4418" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2414", "end_pos": "2414" }, { "start_pos": "2605", "end_pos": "2605" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1301", "end_pos": "1301" }, { "start_pos": "1305", "end_pos": "1305" }, { "start_pos": "1323", "end_pos": "1323" }, { "start_pos": "1325", "end_pos": "1325" }, { "start_pos": "1355", "end_pos": "1355" }, { "start_pos": "1406", "end_pos": "1406" }, { "start_pos": "1805", "end_pos": "1805" }, { "start_pos": "1808", "end_pos": "1808" }, { "start_pos": "2601", "end_pos": "2601" }, { "start_pos": "2603", "end_pos": "2603" }, { "start_pos": "2755", "end_pos": "2755" }, { "start_pos": "3562", "end_pos": "3562" }, { "start_pos": "3653", "end_pos": "3653" }, { "start_pos": "4124", "end_pos": "4124" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "A2AAE1-1.1305.1305", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "A2AAE1-1.1305.1305", "start_pos": 1305, "end_pos": 1305, "uniprot_canonical_ac": "A2AAE1-1", "length": 5005, "uniprot_id": "BLTP1_MOUSE", "protein_name": "Bridge-like lipid transfer protein family member 1", "refseq_ac": "NP_766267", "refseq_name": "bridge-like lipid transfer protein family member 1", "gene_name": "Bltp1", "gene_names_uniprotkb": "Bltp1; 4932438A13Rik; Fsa; Kiaa1109; Kiaa1371", "gene_names_refseq": "4732443H21; 4932438A13Rik; B830039D19Rik; Bltp1; D630029K19Rik; FSA; Kiaa1109; Tweek", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GTSPVSPNTQDKSVGQSPLR", "down_seq": "PLKRQASVCSTRLGSTKSLT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1" } ], "site_lbl": "Ser1305" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1899", "end_pos": "1899" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "2555", "end_pos": "2555" }, { "start_pos": "2605", "end_pos": "2605" }, { "start_pos": "4418", "end_pos": "4418" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2414", "end_pos": "2414" }, { "start_pos": "2605", "end_pos": "2605" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1301", "end_pos": "1301" }, { "start_pos": "1305", "end_pos": "1305" }, { "start_pos": "1323", "end_pos": "1323" }, { "start_pos": "1325", "end_pos": "1325" }, { "start_pos": "1355", "end_pos": "1355" }, { "start_pos": "1406", "end_pos": "1406" }, { "start_pos": "1805", "end_pos": "1805" }, { "start_pos": "1808", "end_pos": "1808" }, { "start_pos": "2601", "end_pos": "2601" }, { "start_pos": "2603", "end_pos": "2603" }, { "start_pos": "2755", "end_pos": "2755" }, { "start_pos": "3562", "end_pos": "3562" }, { "start_pos": "3653", "end_pos": "3653" }, { "start_pos": "4124", "end_pos": "4124" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "A2AAE1-1.1301.1301", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "A2AAE1-1.1323.1323", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "A2AAE1-1.1325.1325", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "A2AAE1-1.1323.1323", "start_pos": 1323, "end_pos": 1323, "uniprot_canonical_ac": "A2AAE1-1", "length": 5005, "uniprot_id": "BLTP1_MOUSE", "protein_name": "Bridge-like lipid transfer protein family member 1", "refseq_ac": "NP_766267", "refseq_name": "bridge-like lipid transfer protein family member 1", "gene_name": "Bltp1", "gene_names_uniprotkb": "Bltp1; 4932438A13Rik; Fsa; Kiaa1109; Kiaa1371", "gene_names_refseq": "4732443H21; 4932438A13Rik; B830039D19Rik; Bltp1; D630029K19Rik; FSA; Kiaa1109; Tweek", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1" }, { "database": "iPTMnet", "id": "A2AAE1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AAE1" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "A2AAE1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AAE1", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LRSPLKRQASVCSTRLGSTK", "down_seq": "LTAAFYGDKQPVTVGVQFSS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "A2AAE1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AAE1" } ], "site_lbl": "Ser1323" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1899", "end_pos": "1899" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "2555", "end_pos": "2555" }, { "start_pos": "2605", "end_pos": "2605" }, { "start_pos": "4418", "end_pos": "4418" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2414", "end_pos": "2414" }, { "start_pos": "2605", "end_pos": "2605" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1301", "end_pos": "1301" }, { "start_pos": "1305", "end_pos": "1305" }, { "start_pos": "1323", "end_pos": "1323" }, { "start_pos": "1325", "end_pos": "1325" }, { "start_pos": "1355", "end_pos": "1355" }, { "start_pos": "1406", "end_pos": "1406" }, { "start_pos": "1805", "end_pos": "1805" }, { "start_pos": "1808", "end_pos": "1808" }, { "start_pos": "2601", "end_pos": "2601" }, { "start_pos": "2603", "end_pos": "2603" }, { "start_pos": "2755", "end_pos": "2755" }, { "start_pos": "3562", "end_pos": "3562" }, { "start_pos": "3653", "end_pos": "3653" }, { "start_pos": "4124", "end_pos": "4124" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "A2AAE1-1.1305.1305", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "A2AAE1-1.1325.1325", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "A2AAE1-1.1325.1325", "start_pos": 1325, "end_pos": 1325, "uniprot_canonical_ac": "A2AAE1-1", "length": 5005, "uniprot_id": "BLTP1_MOUSE", "protein_name": "Bridge-like lipid transfer protein family member 1", "refseq_ac": "NP_766267", "refseq_name": "bridge-like lipid transfer protein family member 1", "gene_name": "Bltp1", "gene_names_uniprotkb": "Bltp1; 4932438A13Rik; Fsa; Kiaa1109; Kiaa1371", "gene_names_refseq": "4732443H21; 4932438A13Rik; B830039D19Rik; Bltp1; D630029K19Rik; FSA; Kiaa1109; Tweek", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "SPLKRQASVCSTRLGSTKSL", "down_seq": "AAFYGDKQPVTVGVQFSSDV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1" } ], "site_lbl": "Thr1325" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1899", "end_pos": "1899" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "2555", "end_pos": "2555" }, { "start_pos": "2605", "end_pos": "2605" }, { "start_pos": "4418", "end_pos": "4418" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2414", "end_pos": "2414" }, { "start_pos": "2605", "end_pos": "2605" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1301", "end_pos": "1301" }, { "start_pos": "1305", "end_pos": "1305" }, { "start_pos": "1323", "end_pos": "1323" }, { "start_pos": "1325", "end_pos": "1325" }, { "start_pos": "1355", "end_pos": "1355" }, { "start_pos": "1406", "end_pos": "1406" }, { "start_pos": "1805", "end_pos": "1805" }, { "start_pos": "1808", "end_pos": "1808" }, { "start_pos": "2601", "end_pos": "2601" }, { "start_pos": "2603", "end_pos": "2603" }, { "start_pos": "2755", "end_pos": "2755" }, { "start_pos": "3562", "end_pos": "3562" }, { "start_pos": "3653", "end_pos": "3653" }, { "start_pos": "4124", "end_pos": "4124" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "A2AAE1-1.1305.1305", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "A2AAE1-1.1323.1323", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "A2AAE1-1.1355.1355", "start_pos": 1355, "end_pos": 1355, "uniprot_canonical_ac": "A2AAE1-1", "length": 5005, "uniprot_id": "BLTP1_MOUSE", "protein_name": "Bridge-like lipid transfer protein family member 1", "refseq_ac": "NP_766267", "refseq_name": "bridge-like lipid transfer protein family member 1", "gene_name": "Bltp1", "gene_names_uniprotkb": "Bltp1; 4932438A13Rik; Fsa; Kiaa1109; Kiaa1371", "gene_names_refseq": "4732443H21; 4932438A13Rik; B830039D19Rik; Bltp1; D630029K19Rik; FSA; Kiaa1109; Tweek", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1" }, { "database": "iPTMnet", "id": "A2AAE1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AAE1" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "A2AAE1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AAE1", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VTVGVQFSSDVSRSDENVLD", "down_seq": "PKQRRSFGSFPYTPSADSNS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "A2AAE1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AAE1" } ], "site_lbl": "Ser1355" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1899", "end_pos": "1899" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "2555", "end_pos": "2555" }, { "start_pos": "2605", "end_pos": "2605" }, { "start_pos": "4418", "end_pos": "4418" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2414", "end_pos": "2414" }, { "start_pos": "2605", "end_pos": "2605" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1301", "end_pos": "1301" }, { "start_pos": "1305", "end_pos": "1305" }, { "start_pos": "1323", "end_pos": "1323" }, { "start_pos": "1325", "end_pos": "1325" }, { "start_pos": "1355", "end_pos": "1355" }, { "start_pos": "1406", "end_pos": "1406" }, { "start_pos": "1805", "end_pos": "1805" }, { "start_pos": "1808", "end_pos": "1808" }, { "start_pos": "2601", "end_pos": "2601" }, { "start_pos": "2603", "end_pos": "2603" }, { "start_pos": "2755", "end_pos": "2755" }, { "start_pos": "3562", "end_pos": "3562" }, { "start_pos": "3653", "end_pos": "3653" }, { "start_pos": "4124", "end_pos": "4124" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "A2AAE1-1.1406.1406", "start_pos": 1406, "end_pos": 1406, "uniprot_canonical_ac": "A2AAE1-1", "length": 5005, "uniprot_id": "BLTP1_MOUSE", "protein_name": "Bridge-like lipid transfer protein family member 1", "refseq_ac": "NP_766267", "refseq_name": "bridge-like lipid transfer protein family member 1", "gene_name": "Bltp1", "gene_names_uniprotkb": "Bltp1; 4932438A13Rik; Fsa; Kiaa1109; Kiaa1371", "gene_names_refseq": "4732443H21; 4932438A13Rik; B830039D19Rik; Bltp1; D630029K19Rik; FSA; Kiaa1109; Tweek", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MSMADSEAYFSAAEEFEPIS", "down_seq": "DEGPGTYPGRKKKKKQMQQI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1" } ], "site_lbl": "Ser1406" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1899", "end_pos": "1899" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "2555", "end_pos": "2555" }, { "start_pos": "2605", "end_pos": "2605" }, { "start_pos": "4418", "end_pos": "4418" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2414", "end_pos": "2414" }, { "start_pos": "2605", "end_pos": "2605" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1301", "end_pos": "1301" }, { "start_pos": "1305", "end_pos": "1305" }, { "start_pos": "1323", "end_pos": "1323" }, { "start_pos": "1325", "end_pos": "1325" }, { "start_pos": "1355", "end_pos": "1355" }, { "start_pos": "1406", "end_pos": "1406" }, { "start_pos": "1805", "end_pos": "1805" }, { "start_pos": "1808", "end_pos": "1808" }, { "start_pos": "2601", "end_pos": "2601" }, { "start_pos": "2603", "end_pos": "2603" }, { "start_pos": "2755", "end_pos": "2755" }, { "start_pos": "3562", "end_pos": "3562" }, { "start_pos": "3653", "end_pos": "3653" }, { "start_pos": "4124", "end_pos": "4124" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "A2AAE1-1.1805.1805", "start_pos": 1805, "end_pos": 1805, "uniprot_canonical_ac": "A2AAE1-1", "length": 5005, "uniprot_id": "BLTP1_MOUSE", "protein_name": "Bridge-like lipid transfer protein family member 1", "refseq_ac": "NP_766267", "refseq_name": "bridge-like lipid transfer protein family member 1", "gene_name": "Bltp1", "gene_names_uniprotkb": "Bltp1; 4932438A13Rik; Fsa; Kiaa1109; Kiaa1371", "gene_names_refseq": "4732443H21; 4932438A13Rik; B830039D19Rik; Bltp1; D630029K19Rik; FSA; Kiaa1109; Tweek", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1" }, { "database": "iPTMnet", "id": "A2AAE1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AAE1" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "A2AAE1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AAE1", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KTSNFDRYVHASKMQPQSSG", "down_seq": "LRSNAGAEKGKEIAAKLNIH", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "A2AAE1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AAE1" } ], "site_lbl": "Ser1805" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1899", "end_pos": "1899" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "2555", "end_pos": "2555" }, { "start_pos": "2605", "end_pos": "2605" }, { "start_pos": "4418", "end_pos": "4418" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2414", "end_pos": "2414" }, { "start_pos": "2605", "end_pos": "2605" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1301", "end_pos": "1301" }, { "start_pos": "1305", "end_pos": "1305" }, { "start_pos": "1323", "end_pos": "1323" }, { "start_pos": "1325", "end_pos": "1325" }, { "start_pos": "1355", "end_pos": "1355" }, { "start_pos": "1406", "end_pos": "1406" }, { "start_pos": "1805", "end_pos": "1805" }, { "start_pos": "1808", "end_pos": "1808" }, { "start_pos": "2601", "end_pos": "2601" }, { "start_pos": "2603", "end_pos": "2603" }, { "start_pos": "2755", "end_pos": "2755" }, { "start_pos": "3562", "end_pos": "3562" }, { "start_pos": "3653", "end_pos": "3653" }, { "start_pos": "4124", "end_pos": "4124" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "A2AAE1-1.1808.1808", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "A2AAE1-1.1808.1808", "start_pos": 1808, "end_pos": 1808, "uniprot_canonical_ac": "A2AAE1-1", "length": 5005, "uniprot_id": "BLTP1_MOUSE", "protein_name": "Bridge-like lipid transfer protein family member 1", "refseq_ac": "NP_766267", "refseq_name": "bridge-like lipid transfer protein family member 1", "gene_name": "Bltp1", "gene_names_uniprotkb": "Bltp1; 4932438A13Rik; Fsa; Kiaa1109; Kiaa1371", "gene_names_refseq": "4732443H21; 4932438A13Rik; B830039D19Rik; Bltp1; D630029K19Rik; FSA; Kiaa1109; Tweek", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1" }, { "database": "iPTMnet", "id": "A2AAE1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AAE1" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "A2AAE1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AAE1", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NFDRYVHASKMQPQSSGSLR", "down_seq": "NAGAEKGKEIAAKLNIHRVH", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "A2AAE1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AAE1" } ], "site_lbl": "Ser1808" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1899", "end_pos": "1899" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "2555", "end_pos": "2555" }, { "start_pos": "2605", "end_pos": "2605" }, { "start_pos": "4418", "end_pos": "4418" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2414", "end_pos": "2414" }, { "start_pos": "2605", "end_pos": "2605" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1301", "end_pos": "1301" }, { "start_pos": "1305", "end_pos": "1305" }, { "start_pos": "1323", "end_pos": "1323" }, { "start_pos": "1325", "end_pos": "1325" }, { "start_pos": "1355", "end_pos": "1355" }, { "start_pos": "1406", "end_pos": "1406" }, { "start_pos": "1805", "end_pos": "1805" }, { "start_pos": "1808", "end_pos": "1808" }, { "start_pos": "2601", "end_pos": "2601" }, { "start_pos": "2603", "end_pos": "2603" }, { "start_pos": "2755", "end_pos": "2755" }, { "start_pos": "3562", "end_pos": "3562" }, { "start_pos": "3653", "end_pos": "3653" }, { "start_pos": "4124", "end_pos": "4124" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "A2AAE1-1.1805.1805", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "A2AAE1-1.2601.2601", "start_pos": 2601, "end_pos": 2601, "uniprot_canonical_ac": "A2AAE1-1", "length": 5005, "uniprot_id": "BLTP1_MOUSE", "protein_name": "Bridge-like lipid transfer protein family member 1", "refseq_ac": "NP_766267", "refseq_name": "bridge-like lipid transfer protein family member 1", "gene_name": "Bltp1", "gene_names_uniprotkb": "Bltp1; 4932438A13Rik; Fsa; Kiaa1109; Kiaa1371", "gene_names_refseq": "4732443H21; 4932438A13Rik; B830039D19Rik; Bltp1; D630029K19Rik; FSA; Kiaa1109; Tweek", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1" }, { "database": "iPTMnet", "id": "A2AAE1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AAE1" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "A2AAE1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AAE1", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MIDDIKATQTDIKLSRYTAG", "down_seq": "ASPTPTFKTRKHRDFRSSDF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "A2AAE1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AAE1" } ], "site_lbl": "Ser2601" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1899", "end_pos": "1899" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "2555", "end_pos": "2555" }, { "start_pos": "2605", "end_pos": "2605" }, { "start_pos": "4418", "end_pos": "4418" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2414", "end_pos": "2414" }, { "start_pos": "2605", "end_pos": "2605" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1301", "end_pos": "1301" }, { "start_pos": "1305", "end_pos": "1305" }, { "start_pos": "1323", "end_pos": "1323" }, { "start_pos": "1325", "end_pos": "1325" }, { "start_pos": "1355", "end_pos": "1355" }, { "start_pos": "1406", "end_pos": "1406" }, { "start_pos": "1805", "end_pos": "1805" }, { "start_pos": "1808", "end_pos": "1808" }, { "start_pos": "2601", "end_pos": "2601" }, { "start_pos": "2603", "end_pos": "2603" }, { "start_pos": "2755", "end_pos": "2755" }, { "start_pos": "3562", "end_pos": "3562" }, { "start_pos": "3653", "end_pos": "3653" }, { "start_pos": "4124", "end_pos": "4124" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "A2AAE1-1.2603.2603", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "A2AAE1-1.2605.2605", "categories": [ "glycosylation_flag", "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "A2AAE1-1.2603.2603", "start_pos": 2603, "end_pos": 2603, "uniprot_canonical_ac": "A2AAE1-1", "length": 5005, "uniprot_id": "BLTP1_MOUSE", "protein_name": "Bridge-like lipid transfer protein family member 1", "refseq_ac": "NP_766267", "refseq_name": "bridge-like lipid transfer protein family member 1", "gene_name": "Bltp1", "gene_names_uniprotkb": "Bltp1; 4932438A13Rik; Fsa; Kiaa1109; Kiaa1371", "gene_names_refseq": "4732443H21; 4932438A13Rik; B830039D19Rik; Bltp1; D630029K19Rik; FSA; Kiaa1109; Tweek", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DDIKATQTDIKLSRYTAGSA", "down_seq": "PTPTFKTRKHRDFRSSDFSR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1" } ], "site_lbl": "Ser2603" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1899", "end_pos": "1899" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "2555", "end_pos": "2555" }, { "start_pos": "2605", "end_pos": "2605" }, { "start_pos": "4418", "end_pos": "4418" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2414", "end_pos": "2414" }, { "start_pos": "2605", "end_pos": "2605" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1301", "end_pos": "1301" }, { "start_pos": "1305", "end_pos": "1305" }, { "start_pos": "1323", "end_pos": "1323" }, { "start_pos": "1325", "end_pos": "1325" }, { "start_pos": "1355", "end_pos": "1355" }, { "start_pos": "1406", "end_pos": "1406" }, { "start_pos": "1805", "end_pos": "1805" }, { "start_pos": "1808", "end_pos": "1808" }, { "start_pos": "2601", "end_pos": "2601" }, { "start_pos": "2603", "end_pos": "2603" }, { "start_pos": "2755", "end_pos": "2755" }, { "start_pos": "3562", "end_pos": "3562" }, { "start_pos": "3653", "end_pos": "3653" }, { "start_pos": "4124", "end_pos": "4124" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "A2AAE1-1.2601.2601", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "A2AAE1-1.2605.2605", "categories": [ "glycosylation_flag", "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "A2AAE1-1.2755.2755", "start_pos": 2755, "end_pos": 2755, "uniprot_canonical_ac": "A2AAE1-1", "length": 5005, "uniprot_id": "BLTP1_MOUSE", "protein_name": "Bridge-like lipid transfer protein family member 1", "refseq_ac": "NP_766267", "refseq_name": "bridge-like lipid transfer protein family member 1", "gene_name": "Bltp1", "gene_names_uniprotkb": "Bltp1; 4932438A13Rik; Fsa; Kiaa1109; Kiaa1371", "gene_names_refseq": "4732443H21; 4932438A13Rik; B830039D19Rik; Bltp1; D630029K19Rik; FSA; Kiaa1109; Tweek", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "The phagosomal proteome in interferon-gamma-activated macrophages.", "journal": "Immunity", "date": "2009", "authors": "Trost M, English L, Lemieux S, Courcelles M, Desjardins M, Thibault P", "evidence": [ { "database": "UniProtKB", "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1" }, { "database": "iPTMnet", "id": "A2AAE1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AAE1" } ], "reference": [ { "type": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" } ] } ], "crossref": [ { "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319", "database": "PubMed", "categories": [ "Other" ] }, { "id": "A2AAE1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AAE1", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VRSPTEPTCRVVFENEQDNN", "down_seq": "LTKTQRKRSLVTSEPQHVTL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1" }, { "database": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" }, { "database": "iPTMnet", "id": "A2AAE1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AAE1" } ], "site_lbl": "Ser2755" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1899", "end_pos": "1899" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "2555", "end_pos": "2555" }, { "start_pos": "2605", "end_pos": "2605" }, { "start_pos": "4418", "end_pos": "4418" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2414", "end_pos": "2414" }, { "start_pos": "2605", "end_pos": "2605" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1301", "end_pos": "1301" }, { "start_pos": "1305", "end_pos": "1305" }, { "start_pos": "1323", "end_pos": "1323" }, { "start_pos": "1325", "end_pos": "1325" }, { "start_pos": "1355", "end_pos": "1355" }, { "start_pos": "1406", "end_pos": "1406" }, { "start_pos": "1805", "end_pos": "1805" }, { "start_pos": "1808", "end_pos": "1808" }, { "start_pos": "2601", "end_pos": "2601" }, { "start_pos": "2603", "end_pos": "2603" }, { "start_pos": "2755", "end_pos": "2755" }, { "start_pos": "3562", "end_pos": "3562" }, { "start_pos": "3653", "end_pos": "3653" }, { "start_pos": "4124", "end_pos": "4124" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "A2AAE1-1.3562.3562", "start_pos": 3562, "end_pos": 3562, "uniprot_canonical_ac": "A2AAE1-1", "length": 5005, "uniprot_id": "BLTP1_MOUSE", "protein_name": "Bridge-like lipid transfer protein family member 1", "refseq_ac": "NP_766267", "refseq_name": "bridge-like lipid transfer protein family member 1", "gene_name": "Bltp1", "gene_names_uniprotkb": "Bltp1; 4932438A13Rik; Fsa; Kiaa1109; Kiaa1371", "gene_names_refseq": "4732443H21; 4932438A13Rik; B830039D19Rik; Bltp1; D630029K19Rik; FSA; Kiaa1109; Tweek", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DIRELNEQAKVIDDLKKLGA", "down_seq": "EGTINQEIQRYQQLESVAVN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1" } ], "site_lbl": "Ser3562" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1899", "end_pos": "1899" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "2555", "end_pos": "2555" }, { "start_pos": "2605", "end_pos": "2605" }, { "start_pos": "4418", "end_pos": "4418" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2414", "end_pos": "2414" }, { "start_pos": "2605", "end_pos": "2605" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1301", "end_pos": "1301" }, { "start_pos": "1305", "end_pos": "1305" }, { "start_pos": "1323", "end_pos": "1323" }, { "start_pos": "1325", "end_pos": "1325" }, { "start_pos": "1355", "end_pos": "1355" }, { "start_pos": "1406", "end_pos": "1406" }, { "start_pos": "1805", "end_pos": "1805" }, { "start_pos": "1808", "end_pos": "1808" }, { "start_pos": "2601", "end_pos": "2601" }, { "start_pos": "2603", "end_pos": "2603" }, { "start_pos": "2755", "end_pos": "2755" }, { "start_pos": "3562", "end_pos": "3562" }, { "start_pos": "3653", "end_pos": "3653" }, { "start_pos": "4124", "end_pos": "4124" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "A2AAE1-1.3653.3653", "start_pos": 3653, "end_pos": 3653, "uniprot_canonical_ac": "A2AAE1-1", "length": 5005, "uniprot_id": "BLTP1_MOUSE", "protein_name": "Bridge-like lipid transfer protein family member 1", "refseq_ac": "NP_766267", "refseq_name": "bridge-like lipid transfer protein family member 1", "gene_name": "Bltp1", "gene_names_uniprotkb": "Bltp1; 4932438A13Rik; Fsa; Kiaa1109; Kiaa1371", "gene_names_refseq": "4732443H21; 4932438A13Rik; B830039D19Rik; Bltp1; D630029K19Rik; FSA; Kiaa1109; Tweek", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "The phagosomal proteome in interferon-gamma-activated macrophages.", "journal": "Immunity", "date": "2009", "authors": "Trost M, English L, Lemieux S, Courcelles M, Desjardins M, Thibault P", "evidence": [ { "database": "UniProtKB", "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1" }, { "database": "iPTMnet", "id": "A2AAE1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AAE1" } ], "reference": [ { "type": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" } ] } ], "crossref": [ { "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319", "database": "PubMed", "categories": [ "Other" ] }, { "id": "A2AAE1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AAE1", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RASSRIGETDELPEIRVDAA", "down_seq": "PGPRVTFNIQDTFPEETELD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1" }, { "database": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" }, { "database": "iPTMnet", "id": "A2AAE1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AAE1" } ], "site_lbl": "Ser3653" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1899", "end_pos": "1899" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "2555", "end_pos": "2555" }, { "start_pos": "2605", "end_pos": "2605" }, { "start_pos": "4418", "end_pos": "4418" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2414", "end_pos": "2414" }, { "start_pos": "2605", "end_pos": "2605" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1301", "end_pos": "1301" }, { "start_pos": "1305", "end_pos": "1305" }, { "start_pos": "1323", "end_pos": "1323" }, { "start_pos": "1325", "end_pos": "1325" }, { "start_pos": "1355", "end_pos": "1355" }, { "start_pos": "1406", "end_pos": "1406" }, { "start_pos": "1805", "end_pos": "1805" }, { "start_pos": "1808", "end_pos": "1808" }, { "start_pos": "2601", "end_pos": "2601" }, { "start_pos": "2603", "end_pos": "2603" }, { "start_pos": "2755", "end_pos": "2755" }, { "start_pos": "3562", "end_pos": "3562" }, { "start_pos": "3653", "end_pos": "3653" }, { "start_pos": "4124", "end_pos": "4124" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "A2AAE1-1.4124.4124", "start_pos": 4124, "end_pos": 4124, "uniprot_canonical_ac": "A2AAE1-1", "length": 5005, "uniprot_id": "BLTP1_MOUSE", "protein_name": "Bridge-like lipid transfer protein family member 1", "refseq_ac": "NP_766267", "refseq_name": "bridge-like lipid transfer protein family member 1", "gene_name": "Bltp1", "gene_names_uniprotkb": "Bltp1; 4932438A13Rik; Fsa; Kiaa1109; Kiaa1371", "gene_names_refseq": "4732443H21; 4932438A13Rik; B830039D19Rik; Bltp1; D630029K19Rik; FSA; Kiaa1109; Tweek", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1" }, { "database": "iPTMnet", "id": "A2AAE1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AAE1" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "A2AAE1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AAE1", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QTGAKTSASKAGMPGSSGLG", "down_seq": "PLGRSRHSSSQSDLTGSSSS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2AAE1", "url": "https://www.uniprot.org/uniprotkb/A2AAE1" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "A2AAE1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AAE1" } ], "site_lbl": "Ser4124" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1899", "end_pos": "1899" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "2555", "end_pos": "2555" }, { "start_pos": "2605", "end_pos": "2605" }, { "start_pos": "4418", "end_pos": "4418" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2414", "end_pos": "2414" }, { "start_pos": "2605", "end_pos": "2605" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1301", "end_pos": "1301" }, { "start_pos": "1305", "end_pos": "1305" }, { "start_pos": "1323", "end_pos": "1323" }, { "start_pos": "1325", "end_pos": "1325" }, { "start_pos": "1355", "end_pos": "1355" }, { "start_pos": "1406", "end_pos": "1406" }, { "start_pos": "1805", "end_pos": "1805" }, { "start_pos": "1808", "end_pos": "1808" }, { "start_pos": "2601", "end_pos": "2601" }, { "start_pos": "2603", "end_pos": "2603" }, { "start_pos": "2755", "end_pos": "2755" }, { "start_pos": "3562", "end_pos": "3562" }, { "start_pos": "3653", "end_pos": "3653" }, { "start_pos": "4124", "end_pos": "4124" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8VCB2-1.372.372", "start_pos": 372, "end_pos": 372, "uniprot_canonical_ac": "Q8VCB2-1", "length": 745, "uniprot_id": "MED25_MOUSE", "protein_name": "Mediator of RNA polymerase II transcription subunit 25", "refseq_ac": "NP_001318135", "refseq_name": "mediator of RNA polymerase II transcription subunit 25 isoform 2", "gene_name": "Med25", "gene_names_uniprotkb": "Med25", "gene_names_refseq": "2610034E13Rik; 2610529E18Rik; ESTM2; Med25", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VCB2", "url": "https://www.uniprot.org/uniprotkb/Q8VCB2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "PGPVLAAPAQPGAPSLAGTV", "down_seq": "PGGVNGPSAAQLGGPALGGQ", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr372", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "372", "end_pos": "372" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8VCB2-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "Q8VCB2-1", "length": 745, "uniprot_id": "MED25_MOUSE", "protein_name": "Mediator of RNA polymerase II transcription subunit 25", "refseq_ac": "NP_001318135", "refseq_name": "mediator of RNA polymerase II transcription subunit 25 isoform 2", "gene_name": "Med25", "gene_names_uniprotkb": "Med25", "gene_names_refseq": "2610034E13Rik; 2610529E18Rik; ESTM2; Med25", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VCB2", "url": "https://www.uniprot.org/uniprotkb/Q8VCB2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8VCB2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8VCB2" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] } ], "crossref": [ { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8VCB2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8VCB2", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "Q8VCB2", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8VCB2" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "372", "end_pos": "372" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CB67-1.152.152", "start_pos": 152, "end_pos": 152, "uniprot_canonical_ac": "Q8CB67-1", "length": 483, "uniprot_id": "LRP11_MOUSE", "protein_name": "Low-density lipoprotein receptor-related protein 11", "refseq_ac": "NP_766372", "refseq_name": "low-density lipoprotein receptor-related protein 11 isoform 1 precursor", "gene_name": "Lrp11", "gene_names_uniprotkb": "Lrp11", "gene_names_refseq": "1700034J19Rik; 6330533B21; 9830160H19Rik; Lrp11", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CB67", "url": "https://www.uniprot.org/uniprotkb/Q8CB67" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "Q8CB67", "url": "https://www.uniprot.org/uniprotkb/Q8CB67", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "QLPRGPSVPAPMPAPRCYLF", "down_seq": "CTARGRSVCKFAPLRGYRTY", "glycosylation": [ { "glytoucan_ac": "G02815KT", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "CYLFNCTAR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn152", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn152", "evidence": [ { "id": "Q8CB67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8CB67#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "152", "end_pos": "152" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "403", "end_pos": "403" } ] }, { "type": "snv", "site_list": [ { "start_pos": "303", "end_pos": "303" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "326", "end_pos": "326" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "474", "end_pos": "474" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CB67-1.275.275", "start_pos": 275, "end_pos": 275, "uniprot_canonical_ac": "Q8CB67-1", "length": 483, "uniprot_id": "LRP11_MOUSE", "protein_name": "Low-density lipoprotein receptor-related protein 11", "refseq_ac": "NP_766372", "refseq_name": "low-density lipoprotein receptor-related protein 11 isoform 1 precursor", "gene_name": "Lrp11", "gene_names_uniprotkb": "Lrp11", "gene_names_refseq": "1700034J19Rik; 6330533B21; 9830160H19Rik; Lrp11", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CB67", "url": "https://www.uniprot.org/uniprotkb/Q8CB67" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "Q8CB67", "url": "https://www.uniprot.org/uniprotkb/Q8CB67", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "EGAYIFQLTVTDSVGQRSSD", "down_seq": "VSVTVLPRPYSTGGCSSACS", "glycosylation": [ { "glytoucan_ac": "G23505EP", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "SSDNVSVTVLPR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn275", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn275", "evidence": [ { "id": "Q8CB67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8CB67#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "152", "end_pos": "152" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "403", "end_pos": "403" } ] }, { "type": "snv", "site_list": [ { "start_pos": "303", "end_pos": "303" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "326", "end_pos": "326" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "474", "end_pos": "474" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CB67-1.403.403", "start_pos": 403, "end_pos": 403, "uniprot_canonical_ac": "Q8CB67-1", "length": 483, "uniprot_id": "LRP11_MOUSE", "protein_name": "Low-density lipoprotein receptor-related protein 11", "refseq_ac": "NP_766372", "refseq_name": "low-density lipoprotein receptor-related protein 11 isoform 1 precursor", "gene_name": "Lrp11", "gene_names_uniprotkb": "Lrp11", "gene_names_refseq": "1700034J19Rik; 6330533B21; 9830160H19Rik; Lrp11", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CB67", "url": "https://www.uniprot.org/uniprotkb/Q8CB67" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "Q8CB67", "url": "https://www.uniprot.org/uniprotkb/Q8CB67", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "RIHSTQKAPESQINPVQPDS", "down_seq": "SSGKNQEEGNYDLKSKSGQA", "glycosylation": [ { "glytoucan_ac": "G62765YT", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "APESQINPVQPDSNSSGK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn403", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn403", "evidence": [ { "id": "Q8CB67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8CB67#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "152", "end_pos": "152" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "403", "end_pos": "403" } ] }, { "type": "snv", "site_list": [ { "start_pos": "303", "end_pos": "303" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "326", "end_pos": "326" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "474", "end_pos": "474" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CB67-1.303.303", "start_pos": 303, "end_pos": 303, "uniprot_canonical_ac": "Q8CB67-1", "length": 483, "uniprot_id": "LRP11_MOUSE", "protein_name": "Low-density lipoprotein receptor-related protein 11", "refseq_ac": "NP_766372", "refseq_name": "low-density lipoprotein receptor-related protein 11 isoform 1 precursor", "gene_name": "Lrp11", "gene_names_uniprotkb": "Lrp11", "gene_names_refseq": "1700034J19Rik; 6330533B21; 9830160H19Rik; Lrp11", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CB67", "url": "https://www.uniprot.org/uniprotkb/Q8CB67" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3389084322", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389084322", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RPYSTGGCSSACSRYHFFCD", "down_seq": "GCCIDIALACDGVRQCPDGS", "snv": [ { "evidence": [ { "id": "rs3389084322", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389084322" } ], "glycoeffect": [ "n-glyco-sequon-gain", "o-glyco-site-loss" ], "sequence_org": "S", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (SGC->NGC).", "chr_id": "10", "chr_pos": "7478635", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S303", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "152", "end_pos": "152" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "403", "end_pos": "403" } ] }, { "type": "snv", "site_list": [ { "start_pos": "303", "end_pos": "303" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "326", "end_pos": "326" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "474", "end_pos": "474" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "upstream", "id": "Q8CB67-1.321.321", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8CB67-1.321.321", "start_pos": 321, "end_pos": 321, "uniprot_canonical_ac": "Q8CB67-1", "length": 483, "uniprot_id": "LRP11_MOUSE", "protein_name": "Low-density lipoprotein receptor-related protein 11", "refseq_ac": "NP_766372", "refseq_name": "low-density lipoprotein receptor-related protein 11 isoform 1 precursor", "gene_name": "Lrp11", "gene_names_uniprotkb": "Lrp11", "gene_names_refseq": "1700034J19Rik; 6330533B21; 9830160H19Rik; Lrp11", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CB67", "url": "https://www.uniprot.org/uniprotkb/Q8CB67" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3547631972", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3547631972", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "CDSGCCIDIALACDGVRQCP", "down_seq": "GSDEDFCQNLALDRKLVTHT", "snv": [ { "evidence": [ { "id": "rs3547631972", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3547631972" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "D", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (DGS->NGS).", "chr_id": "10", "chr_pos": "7478688", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "D321", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "152", "end_pos": "152" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "403", "end_pos": "403" } ] }, { "type": "snv", "site_list": [ { "start_pos": "303", "end_pos": "303" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "326", "end_pos": "326" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "474", "end_pos": "474" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "Q8CB67-1.303.303", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q8CB67-1.326.326", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8CB67-1.326.326", "start_pos": 326, "end_pos": 326, "uniprot_canonical_ac": "Q8CB67-1", "length": 483, "uniprot_id": "LRP11_MOUSE", "protein_name": "Low-density lipoprotein receptor-related protein 11", "refseq_ac": "NP_766372", "refseq_name": "low-density lipoprotein receptor-related protein 11 isoform 1 precursor", "gene_name": "Lrp11", "gene_names_uniprotkb": "Lrp11", "gene_names_refseq": "1700034J19Rik; 6330533B21; 9830160H19Rik; Lrp11", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CB67", "url": "https://www.uniprot.org/uniprotkb/Q8CB67" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3547631972", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3547631972", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "CIDIALACDGVRQCPDGSDE", "down_seq": "FCQNLALDRKLVTHTVATSA", "snv": [ { "evidence": [ { "id": "rs3547631972", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3547631972" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "D", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (DFC->NFC).", "chr_id": "10", "chr_pos": "7478688", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "D326", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "152", "end_pos": "152" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "403", "end_pos": "403" } ] }, { "type": "snv", "site_list": [ { "start_pos": "303", "end_pos": "303" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "326", "end_pos": "326" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "474", "end_pos": "474" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "Q8CB67-1.321.321", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8CB67-1.474.474", "start_pos": 474, "end_pos": 474, "uniprot_canonical_ac": "Q8CB67-1", "length": 483, "uniprot_id": "LRP11_MOUSE", "protein_name": "Low-density lipoprotein receptor-related protein 11", "refseq_ac": "NP_766372", "refseq_name": "low-density lipoprotein receptor-related protein 11 isoform 1 precursor", "gene_name": "Lrp11", "gene_names_uniprotkb": "Lrp11", "gene_names_refseq": "1700034J19Rik; 6330533B21; 9830160H19Rik; Lrp11", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CB67", "url": "https://www.uniprot.org/uniprotkb/Q8CB67" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8CB67", "url": "https://www.uniprot.org/uniprotkb/Q8CB67" }, { "database": "iPTMnet", "id": "Q8CB67", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CB67" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q8CB67", "url": "https://www.uniprot.org/uniprotkb/Q8CB67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CB67", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CB67", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "CRLRLVKQKLKKARPITSEE", "down_seq": "DYLINGMYL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8CB67", "url": "https://www.uniprot.org/uniprotkb/Q8CB67" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q8CB67", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CB67" } ], "site_lbl": "Ser474" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "152", "end_pos": "152" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "403", "end_pos": "403" } ] }, { "type": "snv", "site_list": [ { "start_pos": "303", "end_pos": "303" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "326", "end_pos": "326" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "474", "end_pos": "474" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "A2A7S8-1.71.71", "start_pos": 71, "end_pos": 71, "uniprot_canonical_ac": "A2A7S8-1", "length": 1013, "uniprot_id": "NHSL3_MOUSE", "protein_name": "NHS-like protein 3", "refseq_ac": "NP_001028361", "refseq_name": "NHS-like protein 3 isoform a", "gene_name": "Nhsl3", "gene_names_uniprotkb": "Nhsl3; Kiaa1522", "gene_names_refseq": "C77080; Nhsl3; mKIAA1522", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "CBS homogenization mutation strategy narrows the glycan binding profile of a GlcNAc-specific lectin AANL.", "journal": "Glycobiology", "date": "2020", "authors": "Su Y, Ye X, Xu B, Li Y, Yang Q, Yu W, Song J, Guo C, Wang X, Hart GW, Sun H", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "A2A7S8", "url": "https://oglcnac.org/atlas/detail/A2A7S8" } ], "reference": [ { "type": "PubMed", "id": "31616917", "url": "https://glygen.org/publication/PubMed/31616917" } ] } ], "crossref": [ { "id": "31616917", "url": "https://glygen.org/publication/PubMed/31616917", "database": "PubMed", "categories": [ "Other" ] }, { "id": "A2A7S8", "url": "https://oglcnac.org/atlas/detail/A2A7S8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PSGRPPHLEELHTQAQEGLR", "down_seq": "LQHQERQKLSKGGWDHGDTQ", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser71", "evidence": [ { "id": "31616917", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/31616917" }, { "id": "A2A7S8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/A2A7S8" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "71", "end_pos": "71" }, { "start_pos": "801", "end_pos": "801" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "325", "end_pos": "325" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "402", "end_pos": "402" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "610", "end_pos": "610" }, { "start_pos": "667", "end_pos": "667" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "848", "end_pos": "848" }, { "start_pos": "909", "end_pos": "909" }, { "start_pos": "92", "end_pos": "92" }, { "start_pos": "952", "end_pos": "952" }, { "start_pos": "959", "end_pos": "959" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "A2A7S8-1.801.801", "start_pos": 801, "end_pos": 801, "uniprot_canonical_ac": "A2A7S8-1", "length": 1013, "uniprot_id": "NHSL3_MOUSE", "protein_name": "NHS-like protein 3", "refseq_ac": "NP_001028361", "refseq_name": "NHS-like protein 3 isoform a", "gene_name": "Nhsl3", "gene_names_uniprotkb": "Nhsl3; Kiaa1522", "gene_names_refseq": "C77080; Nhsl3; mKIAA1522", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "KDSVGKHSGAPREDSGTPLV", "down_seq": "PSLLQMVRLRSVGASTGIPN", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr801", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "71", "end_pos": "71" }, { "start_pos": "801", "end_pos": "801" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "325", "end_pos": "325" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "402", "end_pos": "402" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "610", "end_pos": "610" }, { "start_pos": "667", "end_pos": "667" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "848", "end_pos": "848" }, { "start_pos": "909", "end_pos": "909" }, { "start_pos": "92", "end_pos": "92" }, { "start_pos": "952", "end_pos": "952" }, { "start_pos": "959", "end_pos": "959" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "A2A7S8-1.108.108", "start_pos": 108, "end_pos": 108, "uniprot_canonical_ac": "A2A7S8-1", "length": 1013, "uniprot_id": "NHSL3_MOUSE", "protein_name": "NHS-like protein 3", "refseq_ac": "NP_001028361", "refseq_name": "NHS-like protein 3 isoform a", "gene_name": "Nhsl3", "gene_names_uniprotkb": "Nhsl3; Kiaa1522", "gene_names_refseq": "C77080; Nhsl3; mKIAA1522", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Quantitative time-resolved phosphoproteomic analysis of mast cell signaling.", "journal": "Journal of immunology (Baltimore, Md. : 1950)", "date": "2007", "authors": "Cao L, Yu K, Banh C, Nguyen V, Ritz A, Raphael BJ, Kawakami Y, Kawakami T, Salomon AR", "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" }, { "database": "iPTMnet", "id": "A2A7S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A7S8" } ], "reference": [ { "type": "PubMed", "id": "17947660", "url": "https://glygen.org/publication/PubMed/17947660" } ] } ], "crossref": [ { "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17947660", "url": "https://glygen.org/publication/PubMed/17947660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "A2A7S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A7S8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "GDTQSIQSSQTGPDEDTISI", "down_seq": "SQKSYMTESSTAEDALSVRS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" }, { "database": "PubMed", "id": "17947660", "url": "https://glygen.org/publication/PubMed/17947660" }, { "database": "iPTMnet", "id": "A2A7S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A7S8" } ], "site_lbl": "Tyr108" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "71", "end_pos": "71" }, { "start_pos": "801", "end_pos": "801" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "325", "end_pos": "325" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "402", "end_pos": "402" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "610", "end_pos": "610" }, { "start_pos": "667", "end_pos": "667" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "848", "end_pos": "848" }, { "start_pos": "909", "end_pos": "909" }, { "start_pos": "92", "end_pos": "92" }, { "start_pos": "952", "end_pos": "952" }, { "start_pos": "959", "end_pos": "959" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "A2A7S8-1.92.92", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "A2A7S8-1.136.136", "start_pos": 136, "end_pos": 136, "uniprot_canonical_ac": "A2A7S8-1", "length": 1013, "uniprot_id": "NHSL3_MOUSE", "protein_name": "NHS-like protein 3", "refseq_ac": "NP_001028361", "refseq_name": "NHS-like protein 3 isoform a", "gene_name": "Nhsl3", "gene_names_uniprotkb": "Nhsl3; Kiaa1522", "gene_names_refseq": "C77080; Nhsl3; mKIAA1522", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ESSTAEDALSVRSEMIQRRG", "down_seq": "TFRPHDSFPKSGKSGRRRRE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" } ], "site_lbl": "Ser136" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "71", "end_pos": "71" }, { "start_pos": "801", "end_pos": "801" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "325", "end_pos": "325" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "402", "end_pos": "402" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "610", "end_pos": "610" }, { "start_pos": "667", "end_pos": "667" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "848", "end_pos": "848" }, { "start_pos": "909", "end_pos": "909" }, { "start_pos": "92", "end_pos": "92" }, { "start_pos": "952", "end_pos": "952" }, { "start_pos": "959", "end_pos": "959" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "upstream", "id": "A2A7S8-1.143.143", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "A2A7S8-1.143.143", "start_pos": 143, "end_pos": 143, "uniprot_canonical_ac": "A2A7S8-1", "length": 1013, "uniprot_id": "NHSL3_MOUSE", "protein_name": "NHS-like protein 3", "refseq_ac": "NP_001028361", "refseq_name": "NHS-like protein 3 isoform a", "gene_name": "Nhsl3", "gene_names_uniprotkb": "Nhsl3; Kiaa1522", "gene_names_refseq": "C77080; Nhsl3; mKIAA1522", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ALSVRSEMIQRRGSTFRPHD", "down_seq": "FPKSGKSGRRRRERRSTVLG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" } ], "site_lbl": "Ser143" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "71", "end_pos": "71" }, { "start_pos": "801", "end_pos": "801" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "325", "end_pos": "325" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "402", "end_pos": "402" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "610", "end_pos": "610" }, { "start_pos": "667", "end_pos": "667" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "848", "end_pos": "848" }, { "start_pos": "909", "end_pos": "909" }, { "start_pos": "92", "end_pos": "92" }, { "start_pos": "952", "end_pos": "952" }, { "start_pos": "959", "end_pos": "959" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "A2A7S8-1.136.136", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "A2A7S8-1.159.159", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "A2A7S8-1.160.160", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "A2A7S8-1.159.159", "start_pos": 159, "end_pos": 159, "uniprot_canonical_ac": "A2A7S8-1", "length": 1013, "uniprot_id": "NHSL3_MOUSE", "protein_name": "NHS-like protein 3", "refseq_ac": "NP_001028361", "refseq_name": "NHS-like protein 3 isoform a", "gene_name": "Nhsl3", "gene_names_uniprotkb": "Nhsl3; Kiaa1522", "gene_names_refseq": "C77080; Nhsl3; mKIAA1522", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RPHDSFPKSGKSGRRRRERR", "down_seq": "TVLGLPQHVQKELGLRNNRE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" } ], "site_lbl": "Ser159" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "71", "end_pos": "71" }, { "start_pos": "801", "end_pos": "801" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "325", "end_pos": "325" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "402", "end_pos": "402" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "610", "end_pos": "610" }, { "start_pos": "667", "end_pos": "667" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "848", "end_pos": "848" }, { "start_pos": "909", "end_pos": "909" }, { "start_pos": "92", "end_pos": "92" }, { "start_pos": "952", "end_pos": "952" }, { "start_pos": "959", "end_pos": "959" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "A2A7S8-1.143.143", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "A2A7S8-1.160.160", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "A2A7S8-1.160.160", "start_pos": 160, "end_pos": 160, "uniprot_canonical_ac": "A2A7S8-1", "length": 1013, "uniprot_id": "NHSL3_MOUSE", "protein_name": "NHS-like protein 3", "refseq_ac": "NP_001028361", "refseq_name": "NHS-like protein 3 isoform a", "gene_name": "Nhsl3", "gene_names_uniprotkb": "Nhsl3; Kiaa1522", "gene_names_refseq": "C77080; Nhsl3; mKIAA1522", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "PHDSFPKSGKSGRRRRERRS", "down_seq": "VLGLPQHVQKELGLRNNREA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" } ], "site_lbl": "Thr160" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "71", "end_pos": "71" }, { "start_pos": "801", "end_pos": "801" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "325", "end_pos": "325" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "402", "end_pos": "402" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "610", "end_pos": "610" }, { "start_pos": "667", "end_pos": "667" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "848", "end_pos": "848" }, { "start_pos": "909", "end_pos": "909" }, { "start_pos": "92", "end_pos": "92" }, { "start_pos": "952", "end_pos": "952" }, { "start_pos": "959", "end_pos": "959" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "A2A7S8-1.143.143", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "A2A7S8-1.159.159", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "A2A7S8-1.213.213", "start_pos": 213, "end_pos": 213, "uniprot_canonical_ac": "A2A7S8-1", "length": 1013, "uniprot_id": "NHSL3_MOUSE", "protein_name": "NHS-like protein 3", "refseq_ac": "NP_001028361", "refseq_name": "NHS-like protein 3 isoform a", "gene_name": "Nhsl3", "gene_names_uniprotkb": "Nhsl3; Kiaa1522", "gene_names_refseq": "C77080; Nhsl3; mKIAA1522", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" }, { "database": "iPTMnet", "id": "A2A7S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A7S8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "A2A7S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A7S8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VRIPTVDGRPGLALGTGVRV", "down_seq": "LQALEAETEAGTDAEAVIQR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "A2A7S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A7S8" } ], "site_lbl": "Ser213" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "71", "end_pos": "71" }, { "start_pos": "801", "end_pos": "801" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "325", "end_pos": "325" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "402", "end_pos": "402" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "610", "end_pos": "610" }, { "start_pos": "667", "end_pos": "667" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "848", "end_pos": "848" }, { "start_pos": "909", "end_pos": "909" }, { "start_pos": "92", "end_pos": "92" }, { "start_pos": "952", "end_pos": "952" }, { "start_pos": "959", "end_pos": "959" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "A2A7S8-1.320.320", "start_pos": 320, "end_pos": 320, "uniprot_canonical_ac": "A2A7S8-1", "length": 1013, "uniprot_id": "NHSL3_MOUSE", "protein_name": "NHS-like protein 3", "refseq_ac": "NP_001028361", "refseq_name": "NHS-like protein 3 isoform a", "gene_name": "Nhsl3", "gene_names_uniprotkb": "Nhsl3; Kiaa1522", "gene_names_refseq": "C77080; Nhsl3; mKIAA1522", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PPTVDVVALGRSSLRTLSRC", "down_seq": "LLSASPASVRSLGRFSSASS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" } ], "site_lbl": "Ser320" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "71", "end_pos": "71" }, { "start_pos": "801", "end_pos": "801" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "325", "end_pos": "325" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "402", "end_pos": "402" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "610", "end_pos": "610" }, { "start_pos": "667", "end_pos": "667" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "848", "end_pos": "848" }, { "start_pos": "909", "end_pos": "909" }, { "start_pos": "92", "end_pos": "92" }, { "start_pos": "952", "end_pos": "952" }, { "start_pos": "959", "end_pos": "959" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "upstream", "id": "A2A7S8-1.325.325", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "A2A7S8-1.328.328", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "A2A7S8-1.336.336", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "A2A7S8-1.337.337", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "A2A7S8-1.339.339", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "A2A7S8-1.340.340", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "A2A7S8-1.325.325", "start_pos": 325, "end_pos": 325, "uniprot_canonical_ac": "A2A7S8-1", "length": 1013, "uniprot_id": "NHSL3_MOUSE", "protein_name": "NHS-like protein 3", "refseq_ac": "NP_001028361", "refseq_name": "NHS-like protein 3 isoform a", "gene_name": "Nhsl3", "gene_names_uniprotkb": "Nhsl3; Kiaa1522", "gene_names_refseq": "C77080; Nhsl3; mKIAA1522", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" }, { "database": "iPTMnet", "id": "A2A7S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A7S8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "A2A7S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A7S8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VVALGRSSLRTLSRCSLLSA", "down_seq": "PASVRSLGRFSSASSPRPRS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "A2A7S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A7S8" } ], "site_lbl": "Ser325" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "71", "end_pos": "71" }, { "start_pos": "801", "end_pos": "801" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "325", "end_pos": "325" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "402", "end_pos": "402" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "610", "end_pos": "610" }, { "start_pos": "667", "end_pos": "667" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "848", "end_pos": "848" }, { "start_pos": "909", "end_pos": "909" }, { "start_pos": "92", "end_pos": "92" }, { "start_pos": "952", "end_pos": "952" }, { "start_pos": "959", "end_pos": "959" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "A2A7S8-1.320.320", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "A2A7S8-1.328.328", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "A2A7S8-1.336.336", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "A2A7S8-1.337.337", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "A2A7S8-1.339.339", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "A2A7S8-1.340.340", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "A2A7S8-1.328.328", "start_pos": 328, "end_pos": 328, "uniprot_canonical_ac": "A2A7S8-1", "length": 1013, "uniprot_id": "NHSL3_MOUSE", "protein_name": "NHS-like protein 3", "refseq_ac": "NP_001028361", "refseq_name": "NHS-like protein 3 isoform a", "gene_name": "Nhsl3", "gene_names_uniprotkb": "Nhsl3; Kiaa1522", "gene_names_refseq": "C77080; Nhsl3; mKIAA1522", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" }, { "database": "iPTMnet", "id": "A2A7S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A7S8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "A2A7S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A7S8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LGRSSLRTLSRCSLLSASPA", "down_seq": "VRSLGRFSSASSPRPRSRNA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "A2A7S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A7S8" } ], "site_lbl": "Ser328" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "71", "end_pos": "71" }, { "start_pos": "801", "end_pos": "801" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "325", "end_pos": "325" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "402", "end_pos": "402" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "610", "end_pos": "610" }, { "start_pos": "667", "end_pos": "667" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "848", "end_pos": "848" }, { "start_pos": "909", "end_pos": "909" }, { "start_pos": "92", "end_pos": "92" }, { "start_pos": "952", "end_pos": "952" }, { "start_pos": "959", "end_pos": "959" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "A2A7S8-1.320.320", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "A2A7S8-1.325.325", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "A2A7S8-1.336.336", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "A2A7S8-1.337.337", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "A2A7S8-1.339.339", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "A2A7S8-1.340.340", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "A2A7S8-1.336.336", "start_pos": 336, "end_pos": 336, "uniprot_canonical_ac": "A2A7S8-1", "length": 1013, "uniprot_id": "NHSL3_MOUSE", "protein_name": "NHS-like protein 3", "refseq_ac": "NP_001028361", "refseq_name": "NHS-like protein 3 isoform a", "gene_name": "Nhsl3", "gene_names_uniprotkb": "Nhsl3; Kiaa1522", "gene_names_refseq": "C77080; Nhsl3; mKIAA1522", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LSRCSLLSASPASVRSLGRF", "down_seq": "SASSPRPRSRNASSSSDNWS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" } ], "site_lbl": "Ser336" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "71", "end_pos": "71" }, { "start_pos": "801", "end_pos": "801" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "325", "end_pos": "325" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "402", "end_pos": "402" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "610", "end_pos": "610" }, { "start_pos": "667", "end_pos": "667" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "848", "end_pos": "848" }, { "start_pos": "909", "end_pos": "909" }, { "start_pos": "92", "end_pos": "92" }, { "start_pos": "952", "end_pos": "952" }, { "start_pos": "959", "end_pos": "959" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "A2A7S8-1.320.320", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "A2A7S8-1.325.325", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "A2A7S8-1.328.328", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "A2A7S8-1.337.337", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "A2A7S8-1.339.339", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "A2A7S8-1.340.340", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "A2A7S8-1.337.337", "start_pos": 337, "end_pos": 337, "uniprot_canonical_ac": "A2A7S8-1", "length": 1013, "uniprot_id": "NHSL3_MOUSE", "protein_name": "NHS-like protein 3", "refseq_ac": "NP_001028361", "refseq_name": "NHS-like protein 3 isoform a", "gene_name": "Nhsl3", "gene_names_uniprotkb": "Nhsl3; Kiaa1522", "gene_names_refseq": "C77080; Nhsl3; mKIAA1522", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SRCSLLSASPASVRSLGRFS", "down_seq": "ASSPRPRSRNASSSSDNWSH", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" } ], "site_lbl": "Ser337" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "71", "end_pos": "71" }, { "start_pos": "801", "end_pos": "801" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "325", "end_pos": "325" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "402", "end_pos": "402" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "610", "end_pos": "610" }, { "start_pos": "667", "end_pos": "667" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "848", "end_pos": "848" }, { "start_pos": "909", "end_pos": "909" }, { "start_pos": "92", "end_pos": "92" }, { "start_pos": "952", "end_pos": "952" }, { "start_pos": "959", "end_pos": "959" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "A2A7S8-1.320.320", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "A2A7S8-1.325.325", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "A2A7S8-1.328.328", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "A2A7S8-1.336.336", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "A2A7S8-1.339.339", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "A2A7S8-1.340.340", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "A2A7S8-1.339.339", "start_pos": 339, "end_pos": 339, "uniprot_canonical_ac": "A2A7S8-1", "length": 1013, "uniprot_id": "NHSL3_MOUSE", "protein_name": "NHS-like protein 3", "refseq_ac": "NP_001028361", "refseq_name": "NHS-like protein 3 isoform a", "gene_name": "Nhsl3", "gene_names_uniprotkb": "Nhsl3; Kiaa1522", "gene_names_refseq": "C77080; Nhsl3; mKIAA1522", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "CSLLSASPASVRSLGRFSSA", "down_seq": "SPRPRSRNASSSSDNWSHSQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" } ], "site_lbl": "Ser339" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "71", "end_pos": "71" }, { "start_pos": "801", "end_pos": "801" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "325", "end_pos": "325" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "402", "end_pos": "402" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "610", "end_pos": "610" }, { "start_pos": "667", "end_pos": "667" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "848", "end_pos": "848" }, { "start_pos": "909", "end_pos": "909" }, { "start_pos": "92", "end_pos": "92" }, { "start_pos": "952", "end_pos": "952" }, { "start_pos": "959", "end_pos": "959" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "A2A7S8-1.320.320", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "A2A7S8-1.325.325", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "A2A7S8-1.328.328", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "A2A7S8-1.336.336", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "A2A7S8-1.337.337", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "A2A7S8-1.340.340", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "A2A7S8-1.340.340", "start_pos": 340, "end_pos": 340, "uniprot_canonical_ac": "A2A7S8-1", "length": 1013, "uniprot_id": "NHSL3_MOUSE", "protein_name": "NHS-like protein 3", "refseq_ac": "NP_001028361", "refseq_name": "NHS-like protein 3 isoform a", "gene_name": "Nhsl3", "gene_names_uniprotkb": "Nhsl3; Kiaa1522", "gene_names_refseq": "C77080; Nhsl3; mKIAA1522", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SLLSASPASVRSLGRFSSAS", "down_seq": "PRPRSRNASSSSDNWSHSQS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" } ], "site_lbl": "Ser340" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "71", "end_pos": "71" }, { "start_pos": "801", "end_pos": "801" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "325", "end_pos": "325" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "402", "end_pos": "402" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "610", "end_pos": "610" }, { "start_pos": "667", "end_pos": "667" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "848", "end_pos": "848" }, { "start_pos": "909", "end_pos": "909" }, { "start_pos": "92", "end_pos": "92" }, { "start_pos": "952", "end_pos": "952" }, { "start_pos": "959", "end_pos": "959" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "A2A7S8-1.320.320", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "A2A7S8-1.325.325", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "A2A7S8-1.328.328", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "A2A7S8-1.336.336", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "A2A7S8-1.337.337", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "A2A7S8-1.339.339", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "A2A7S8-1.398.398", "start_pos": 398, "end_pos": 398, "uniprot_canonical_ac": "A2A7S8-1", "length": 1013, "uniprot_id": "NHSL3_MOUSE", "protein_name": "NHS-like protein 3", "refseq_ac": "NP_001028361", "refseq_name": "NHS-like protein 3 isoform a", "gene_name": "Nhsl3", "gene_names_uniprotkb": "Nhsl3; Kiaa1522", "gene_names_refseq": "C77080; Nhsl3; mKIAA1522", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EGQPEGSVASNNVAPPPPGG", "down_seq": "GRGSPSGGSTAETSDTASIR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" } ], "site_lbl": "Ser398" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "71", "end_pos": "71" }, { "start_pos": "801", "end_pos": "801" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "325", "end_pos": "325" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "402", "end_pos": "402" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "610", "end_pos": "610" }, { "start_pos": "667", "end_pos": "667" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "848", "end_pos": "848" }, { "start_pos": "909", "end_pos": "909" }, { "start_pos": "92", "end_pos": "92" }, { "start_pos": "952", "end_pos": "952" }, { "start_pos": "959", "end_pos": "959" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "A2A7S8-1.402.402", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "A2A7S8-1.407.407", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "A2A7S8-1.402.402", "start_pos": 402, "end_pos": 402, "uniprot_canonical_ac": "A2A7S8-1", "length": 1013, "uniprot_id": "NHSL3_MOUSE", "protein_name": "NHS-like protein 3", "refseq_ac": "NP_001028361", "refseq_name": "NHS-like protein 3 isoform a", "gene_name": "Nhsl3", "gene_names_uniprotkb": "Nhsl3; Kiaa1522", "gene_names_refseq": "C77080; Nhsl3; mKIAA1522", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" }, { "database": "iPTMnet", "id": "A2A7S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A7S8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "title": "The phagosomal proteome in interferon-gamma-activated macrophages.", "journal": "Immunity", "date": "2009", "authors": "Trost M, English L, Lemieux S, Courcelles M, Desjardins M, Thibault P", "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" }, { "database": "iPTMnet", "id": "A2A7S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A7S8" } ], "reference": [ { "type": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" } ] } ], "crossref": [ { "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319", "database": "PubMed", "categories": [ "Other" ] }, { "id": "A2A7S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A7S8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EGSVASNNVAPPPPGGSGRG", "down_seq": "PSGGSTAETSDTASIRSSGQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" }, { "database": "iPTMnet", "id": "A2A7S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A7S8" } ], "site_lbl": "Ser402" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "71", "end_pos": "71" }, { "start_pos": "801", "end_pos": "801" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "325", "end_pos": "325" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "402", "end_pos": "402" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "610", "end_pos": "610" }, { "start_pos": "667", "end_pos": "667" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "848", "end_pos": "848" }, { "start_pos": "909", "end_pos": "909" }, { "start_pos": "92", "end_pos": "92" }, { "start_pos": "952", "end_pos": "952" }, { "start_pos": "959", "end_pos": "959" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "A2A7S8-1.398.398", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "A2A7S8-1.407.407", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "A2A7S8-1.407.407", "start_pos": 407, "end_pos": 407, "uniprot_canonical_ac": "A2A7S8-1", "length": 1013, "uniprot_id": "NHSL3_MOUSE", "protein_name": "NHS-like protein 3", "refseq_ac": "NP_001028361", "refseq_name": "NHS-like protein 3 isoform a", "gene_name": "Nhsl3", "gene_names_uniprotkb": "Nhsl3; Kiaa1522", "gene_names_refseq": "C77080; Nhsl3; mKIAA1522", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" }, { "database": "iPTMnet", "id": "A2A7S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A7S8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "A2A7S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A7S8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SNNVAPPPPGGSGRGSPSGG", "down_seq": "TAETSDTASIRSSGQLSGRS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "A2A7S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A7S8" } ], "site_lbl": "Ser407" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "71", "end_pos": "71" }, { "start_pos": "801", "end_pos": "801" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "325", "end_pos": "325" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "402", "end_pos": "402" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "610", "end_pos": "610" }, { "start_pos": "667", "end_pos": "667" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "848", "end_pos": "848" }, { "start_pos": "909", "end_pos": "909" }, { "start_pos": "92", "end_pos": "92" }, { "start_pos": "952", "end_pos": "952" }, { "start_pos": "959", "end_pos": "959" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "A2A7S8-1.398.398", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "A2A7S8-1.402.402", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "A2A7S8-1.529.529", "start_pos": 529, "end_pos": 529, "uniprot_canonical_ac": "A2A7S8-1", "length": 1013, "uniprot_id": "NHSL3_MOUSE", "protein_name": "NHS-like protein 3", "refseq_ac": "NP_001028361", "refseq_name": "NHS-like protein 3 isoform a", "gene_name": "Nhsl3", "gene_names_uniprotkb": "Nhsl3; Kiaa1522", "gene_names_refseq": "C77080; Nhsl3; mKIAA1522", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" }, { "database": "iPTMnet", "id": "A2A7S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A7S8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "A2A7S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A7S8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "PPRSPERTLSPSSGYSSQSG", "down_seq": "PTLPPKGLAVAPASPGKAQP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "A2A7S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A7S8" } ], "site_lbl": "Thr529" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "71", "end_pos": "71" }, { "start_pos": "801", "end_pos": "801" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "325", "end_pos": "325" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "402", "end_pos": "402" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "610", "end_pos": "610" }, { "start_pos": "667", "end_pos": "667" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "848", "end_pos": "848" }, { "start_pos": "909", "end_pos": "909" }, { "start_pos": "92", "end_pos": "92" }, { "start_pos": "952", "end_pos": "952" }, { "start_pos": "959", "end_pos": "959" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "upstream", "id": "A2A7S8-1.543.543", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "A2A7S8-1.543.543", "start_pos": 543, "end_pos": 543, "uniprot_canonical_ac": "A2A7S8-1", "length": 1013, "uniprot_id": "NHSL3_MOUSE", "protein_name": "NHS-like protein 3", "refseq_ac": "NP_001028361", "refseq_name": "NHS-like protein 3 isoform a", "gene_name": "Nhsl3", "gene_names_uniprotkb": "Nhsl3; Kiaa1522", "gene_names_refseq": "C77080; Nhsl3; mKIAA1522", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" }, { "database": "iPTMnet", "id": "A2A7S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A7S8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "A2A7S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A7S8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "YSSQSGTPTLPPKGLAVAPA", "down_seq": "PGKAQPPKPDRVTSLRSPGA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "A2A7S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A7S8" } ], "site_lbl": "Ser543" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "71", "end_pos": "71" }, { "start_pos": "801", "end_pos": "801" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "325", "end_pos": "325" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "402", "end_pos": "402" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "610", "end_pos": "610" }, { "start_pos": "667", "end_pos": "667" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "848", "end_pos": "848" }, { "start_pos": "909", "end_pos": "909" }, { "start_pos": "92", "end_pos": "92" }, { "start_pos": "952", "end_pos": "952" }, { "start_pos": "959", "end_pos": "959" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "A2A7S8-1.529.529", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "A2A7S8-1.591.591", "start_pos": 591, "end_pos": 591, "uniprot_canonical_ac": "A2A7S8-1", "length": 1013, "uniprot_id": "NHSL3_MOUSE", "protein_name": "NHS-like protein 3", "refseq_ac": "NP_001028361", "refseq_name": "NHS-like protein 3 isoform a", "gene_name": "Nhsl3", "gene_names_uniprotkb": "Nhsl3; Kiaa1522", "gene_names_refseq": "C77080; Nhsl3; mKIAA1522", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "SLCSSSSDPTPLDRSGPQMS", "down_seq": "PLSDRFVIPPHPKVPAPFSP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" } ], "site_lbl": "Thr591" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "71", "end_pos": "71" }, { "start_pos": "801", "end_pos": "801" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "325", "end_pos": "325" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "402", "end_pos": "402" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "610", "end_pos": "610" }, { "start_pos": "667", "end_pos": "667" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "848", "end_pos": "848" }, { "start_pos": "909", "end_pos": "909" }, { "start_pos": "92", "end_pos": "92" }, { "start_pos": "952", "end_pos": "952" }, { "start_pos": "959", "end_pos": "959" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "upstream", "id": "A2A7S8-1.610.610", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "A2A7S8-1.610.610", "start_pos": 610, "end_pos": 610, "uniprot_canonical_ac": "A2A7S8-1", "length": 1013, "uniprot_id": "NHSL3_MOUSE", "protein_name": "NHS-like protein 3", "refseq_ac": "NP_001028361", "refseq_name": "NHS-like protein 3 isoform a", "gene_name": "Nhsl3", "gene_names_uniprotkb": "Nhsl3; Kiaa1522", "gene_names_refseq": "C77080; Nhsl3; mKIAA1522", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "The phagosomal proteome in interferon-gamma-activated macrophages.", "journal": "Immunity", "date": "2009", "authors": "Trost M, English L, Lemieux S, Courcelles M, Desjardins M, Thibault P", "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" }, { "database": "iPTMnet", "id": "A2A7S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A7S8" } ], "reference": [ { "type": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" } ] } ], "crossref": [ { "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319", "database": "PubMed", "categories": [ "Other" ] }, { "id": "A2A7S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A7S8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "STPLSDRFVIPPHPKVPAPF", "down_seq": "PPPSKSKSSNQAAPVLAAPA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" }, { "database": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" }, { "database": "iPTMnet", "id": "A2A7S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A7S8" } ], "site_lbl": "Ser610" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "71", "end_pos": "71" }, { "start_pos": "801", "end_pos": "801" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "325", "end_pos": "325" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "402", "end_pos": "402" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "610", "end_pos": "610" }, { "start_pos": "667", "end_pos": "667" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "848", "end_pos": "848" }, { "start_pos": "909", "end_pos": "909" }, { "start_pos": "92", "end_pos": "92" }, { "start_pos": "952", "end_pos": "952" }, { "start_pos": "959", "end_pos": "959" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "A2A7S8-1.591.591", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "A2A7S8-1.667.667", "start_pos": 667, "end_pos": 667, "uniprot_canonical_ac": "A2A7S8-1", "length": 1013, "uniprot_id": "NHSL3_MOUSE", "protein_name": "NHS-like protein 3", "refseq_ac": "NP_001028361", "refseq_name": "NHS-like protein 3 isoform a", "gene_name": "Nhsl3", "gene_names_uniprotkb": "Nhsl3; Kiaa1522", "gene_names_refseq": "C77080; Nhsl3; mKIAA1522", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SMPQTTLTPAQESPVASKDE", "down_seq": "PPPSPPPSYHPPPPPTKKPE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" } ], "site_lbl": "Ser667" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "71", "end_pos": "71" }, { "start_pos": "801", "end_pos": "801" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "325", "end_pos": "325" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "402", "end_pos": "402" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "610", "end_pos": "610" }, { "start_pos": "667", "end_pos": "667" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "848", "end_pos": "848" }, { "start_pos": "909", "end_pos": "909" }, { "start_pos": "92", "end_pos": "92" }, { "start_pos": "952", "end_pos": "952" }, { "start_pos": "959", "end_pos": "959" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "A2A7S8-1.671.671", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "A2A7S8-1.671.671", "start_pos": 671, "end_pos": 671, "uniprot_canonical_ac": "A2A7S8-1", "length": 1013, "uniprot_id": "NHSL3_MOUSE", "protein_name": "NHS-like protein 3", "refseq_ac": "NP_001028361", "refseq_name": "NHS-like protein 3 isoform a", "gene_name": "Nhsl3", "gene_names_uniprotkb": "Nhsl3; Kiaa1522", "gene_names_refseq": "C77080; Nhsl3; mKIAA1522", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TTLTPAQESPVASKDESPPP", "down_seq": "PPPSYHPPPPPTKKPEVLEE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" } ], "site_lbl": "Ser671" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "71", "end_pos": "71" }, { "start_pos": "801", "end_pos": "801" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "325", "end_pos": "325" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "402", "end_pos": "402" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "610", "end_pos": "610" }, { "start_pos": "667", "end_pos": "667" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "848", "end_pos": "848" }, { "start_pos": "909", "end_pos": "909" }, { "start_pos": "92", "end_pos": "92" }, { "start_pos": "952", "end_pos": "952" }, { "start_pos": "959", "end_pos": "959" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "A2A7S8-1.667.667", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "A2A7S8-1.838.838", "start_pos": 838, "end_pos": 838, "uniprot_canonical_ac": "A2A7S8-1", "length": 1013, "uniprot_id": "NHSL3_MOUSE", "protein_name": "NHS-like protein 3", "refseq_ac": "NP_001028361", "refseq_name": "NHS-like protein 3 isoform a", "gene_name": "Nhsl3", "gene_names_uniprotkb": "Nhsl3; Kiaa1522", "gene_names_refseq": "C77080; Nhsl3; mKIAA1522", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" }, { "database": "iPTMnet", "id": "A2A7S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A7S8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "A2A7S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A7S8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GIPNPSPGSSAPQKPLRRAL", "down_seq": "GRASPVTAPSSGLHAAVRLK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "A2A7S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A7S8" } ], "site_lbl": "Ser838" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "71", "end_pos": "71" }, { "start_pos": "801", "end_pos": "801" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "325", "end_pos": "325" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "402", "end_pos": "402" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "610", "end_pos": "610" }, { "start_pos": "667", "end_pos": "667" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "848", "end_pos": "848" }, { "start_pos": "909", "end_pos": "909" }, { "start_pos": "92", "end_pos": "92" }, { "start_pos": "952", "end_pos": "952" }, { "start_pos": "959", "end_pos": "959" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "A2A7S8-1.842.842", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "A2A7S8-1.848.848", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "A2A7S8-1.842.842", "start_pos": 842, "end_pos": 842, "uniprot_canonical_ac": "A2A7S8-1", "length": 1013, "uniprot_id": "NHSL3_MOUSE", "protein_name": "NHS-like protein 3", "refseq_ac": "NP_001028361", "refseq_name": "NHS-like protein 3 isoform a", "gene_name": "Nhsl3", "gene_names_uniprotkb": "Nhsl3; Kiaa1522", "gene_names_refseq": "C77080; Nhsl3; mKIAA1522", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" }, { "database": "iPTMnet", "id": "A2A7S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A7S8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "A2A7S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A7S8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PSPGSSAPQKPLRRALSGRA", "down_seq": "PVTAPSSGLHAAVRLKASSL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "A2A7S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A7S8" } ], "site_lbl": "Ser842" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "71", "end_pos": "71" }, { "start_pos": "801", "end_pos": "801" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "325", "end_pos": "325" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "402", "end_pos": "402" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "610", "end_pos": "610" }, { "start_pos": "667", "end_pos": "667" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "848", "end_pos": "848" }, { "start_pos": "909", "end_pos": "909" }, { "start_pos": "92", "end_pos": "92" }, { "start_pos": "952", "end_pos": "952" }, { "start_pos": "959", "end_pos": "959" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "A2A7S8-1.838.838", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "A2A7S8-1.848.848", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "A2A7S8-1.848.848", "start_pos": 848, "end_pos": 848, "uniprot_canonical_ac": "A2A7S8-1", "length": 1013, "uniprot_id": "NHSL3_MOUSE", "protein_name": "NHS-like protein 3", "refseq_ac": "NP_001028361", "refseq_name": "NHS-like protein 3 isoform a", "gene_name": "Nhsl3", "gene_names_uniprotkb": "Nhsl3; Kiaa1522", "gene_names_refseq": "C77080; Nhsl3; mKIAA1522", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "APQKPLRRALSGRASPVTAP", "down_seq": "SGLHAAVRLKASSLAASESP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" } ], "site_lbl": "Ser848" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "71", "end_pos": "71" }, { "start_pos": "801", "end_pos": "801" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "325", "end_pos": "325" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "402", "end_pos": "402" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "610", "end_pos": "610" }, { "start_pos": "667", "end_pos": "667" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "848", "end_pos": "848" }, { "start_pos": "909", "end_pos": "909" }, { "start_pos": "92", "end_pos": "92" }, { "start_pos": "952", "end_pos": "952" }, { "start_pos": "959", "end_pos": "959" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "A2A7S8-1.838.838", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "A2A7S8-1.842.842", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "A2A7S8-1.909.909", "start_pos": 909, "end_pos": 909, "uniprot_canonical_ac": "A2A7S8-1", "length": 1013, "uniprot_id": "NHSL3_MOUSE", "protein_name": "NHS-like protein 3", "refseq_ac": "NP_001028361", "refseq_name": "NHS-like protein 3 isoform a", "gene_name": "Nhsl3", "gene_names_uniprotkb": "Nhsl3; Kiaa1522", "gene_names_refseq": "C77080; Nhsl3; mKIAA1522", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "The phagosomal proteome in interferon-gamma-activated macrophages.", "journal": "Immunity", "date": "2009", "authors": "Trost M, English L, Lemieux S, Courcelles M, Desjardins M, Thibault P", "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" }, { "database": "iPTMnet", "id": "A2A7S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A7S8" } ], "reference": [ { "type": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" } ] }, { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" }, { "database": "iPTMnet", "id": "A2A7S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A7S8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "A2A7S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A7S8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SKASFIFSKGTKKLQLERPV", "down_seq": "PEAQADLQRNLVAELRSISE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" }, { "database": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "A2A7S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A7S8" } ], "site_lbl": "Ser909" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "71", "end_pos": "71" }, { "start_pos": "801", "end_pos": "801" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "325", "end_pos": "325" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "402", "end_pos": "402" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "610", "end_pos": "610" }, { "start_pos": "667", "end_pos": "667" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "848", "end_pos": "848" }, { "start_pos": "909", "end_pos": "909" }, { "start_pos": "92", "end_pos": "92" }, { "start_pos": "952", "end_pos": "952" }, { "start_pos": "959", "end_pos": "959" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "A2A7S8-1.92.92", "start_pos": 92, "end_pos": 92, "uniprot_canonical_ac": "A2A7S8-1", "length": 1013, "uniprot_id": "NHSL3_MOUSE", "protein_name": "NHS-like protein 3", "refseq_ac": "NP_001028361", "refseq_name": "NHS-like protein 3 isoform a", "gene_name": "Nhsl3", "gene_names_uniprotkb": "Nhsl3; Kiaa1522", "gene_names_refseq": "C77080; Nhsl3; mKIAA1522", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" }, { "database": "iPTMnet", "id": "A2A7S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A7S8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "A2A7S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A7S8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LQHQERQKLSKGGWDHGDTQ", "down_seq": "IQSSQTGPDEDTISIYSQKS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "A2A7S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A7S8" } ], "site_lbl": "Ser92" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "71", "end_pos": "71" }, { "start_pos": "801", "end_pos": "801" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "325", "end_pos": "325" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "402", "end_pos": "402" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "610", "end_pos": "610" }, { "start_pos": "667", "end_pos": "667" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "848", "end_pos": "848" }, { "start_pos": "909", "end_pos": "909" }, { "start_pos": "92", "end_pos": "92" }, { "start_pos": "952", "end_pos": "952" }, { "start_pos": "959", "end_pos": "959" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "upstream", "id": "A2A7S8-1.108.108", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "A2A7S8-1.952.952", "start_pos": 952, "end_pos": 952, "uniprot_canonical_ac": "A2A7S8-1", "length": 1013, "uniprot_id": "NHSL3_MOUSE", "protein_name": "NHS-like protein 3", "refseq_ac": "NP_001028361", "refseq_name": "NHS-like protein 3 isoform a", "gene_name": "Nhsl3", "gene_names_uniprotkb": "Nhsl3; Kiaa1522", "gene_names_refseq": "C77080; Nhsl3; mKIAA1522", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" }, { "database": "iPTMnet", "id": "A2A7S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A7S8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "A2A7S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A7S8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PPPQAQKKPSKAPPPVARKP", "down_seq": "VGVPPPSPSLPRTESLTAPS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "A2A7S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A7S8" } ], "site_lbl": "Ser952" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "71", "end_pos": "71" }, { "start_pos": "801", "end_pos": "801" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "325", "end_pos": "325" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "402", "end_pos": "402" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "610", "end_pos": "610" }, { "start_pos": "667", "end_pos": "667" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "848", "end_pos": "848" }, { "start_pos": "909", "end_pos": "909" }, { "start_pos": "92", "end_pos": "92" }, { "start_pos": "952", "end_pos": "952" }, { "start_pos": "959", "end_pos": "959" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "upstream", "id": "A2A7S8-1.959.959", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "A2A7S8-1.959.959", "start_pos": 959, "end_pos": 959, "uniprot_canonical_ac": "A2A7S8-1", "length": 1013, "uniprot_id": "NHSL3_MOUSE", "protein_name": "NHS-like protein 3", "refseq_ac": "NP_001028361", "refseq_name": "NHS-like protein 3 isoform a", "gene_name": "Nhsl3", "gene_names_uniprotkb": "Nhsl3; Kiaa1522", "gene_names_refseq": "C77080; Nhsl3; mKIAA1522", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" }, { "database": "iPTMnet", "id": "A2A7S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A7S8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "A2A7S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A7S8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KPSKAPPPVARKPSVGVPPP", "down_seq": "PSLPRTESLTAPSTNGLPHA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2A7S8", "url": "https://www.uniprot.org/uniprotkb/A2A7S8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "A2A7S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A7S8" } ], "site_lbl": "Ser959" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "71", "end_pos": "71" }, { "start_pos": "801", "end_pos": "801" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "325", "end_pos": "325" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "402", "end_pos": "402" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "610", "end_pos": "610" }, { "start_pos": "667", "end_pos": "667" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "848", "end_pos": "848" }, { "start_pos": "909", "end_pos": "909" }, { "start_pos": "92", "end_pos": "92" }, { "start_pos": "952", "end_pos": "952" }, { "start_pos": "959", "end_pos": "959" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "A2A7S8-1.952.952", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6PG16-1.172.172", "start_pos": 172, "end_pos": 172, "uniprot_canonical_ac": "Q6PG16-1", "length": 667, "uniprot_id": "HJURP_MOUSE", "protein_name": "Holliday junction recognition protein", "refseq_ac": "NP_766093", "refseq_name": "Holliday junction recognition protein", "gene_name": "Hjurp", "gene_names_uniprotkb": "Hjurp; Fleg1", "gene_names_refseq": "A730008H23Rik; Fleg1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6PG16", "url": "https://www.uniprot.org/uniprotkb/Q6PG16" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "EKRGGKDTVMTWVPSVTSSV", "down_seq": "PASGCQDAISAKSSGGPEVS", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr172", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "172", "end_pos": "172" } ] }, { "type": "snv", "site_list": [ { "start_pos": "126", "end_pos": "126" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "225", "end_pos": "225" }, { "start_pos": "563", "end_pos": "563" }, { "start_pos": "659", "end_pos": "659" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "169", "end_pos": "169" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "613", "end_pos": "613" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "Q6PG16-1.169.169", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q6PG16-1.185.185", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q6PG16-1.126.126", "start_pos": 126, "end_pos": 126, "uniprot_canonical_ac": "Q6PG16-1", "length": 667, "uniprot_id": "HJURP_MOUSE", "protein_name": "Holliday junction recognition protein", "refseq_ac": "NP_766093", "refseq_name": "Holliday junction recognition protein", "gene_name": "Hjurp", "gene_names_uniprotkb": "Hjurp; Fleg1", "gene_names_refseq": "A730008H23Rik; Fleg1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6PG16", "url": "https://www.uniprot.org/uniprotkb/Q6PG16" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388486746", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388486746", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "L", "start_aa": "L", "up_seq": "AMREASGDPRQRQPAVPGNT", "down_seq": "ETDLRRKYLTQVDILPQDEE", "snv": [ { "evidence": [ { "id": "rs3388486746", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388486746" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "L", "sequence_mut": "S", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (NTL->NTS).", "chr_id": "1", "chr_pos": "88197113", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "L126", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "172", "end_pos": "172" } ] }, { "type": "snv", "site_list": [ { "start_pos": "126", "end_pos": "126" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "225", "end_pos": "225" }, { "start_pos": "563", "end_pos": "563" }, { "start_pos": "659", "end_pos": "659" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "169", "end_pos": "169" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "613", "end_pos": "613" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q6PG16-1.16.16", "start_pos": 16, "end_pos": 16, "uniprot_canonical_ac": "Q6PG16-1", "length": 667, "uniprot_id": "HJURP_MOUSE", "protein_name": "Holliday junction recognition protein", "refseq_ac": "NP_766093", "refseq_name": "Holliday junction recognition protein", "gene_name": "Hjurp", "gene_names_uniprotkb": "Hjurp; Fleg1", "gene_names_refseq": "A730008H23Rik; Fleg1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6PG16", "url": "https://www.uniprot.org/uniprotkb/Q6PG16" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs30298179", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs30298179", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "MESMGRQDRRLHQQL", "down_seq": "ESSSRFQTLMKRLIAKYNQP", "snv": [ { "evidence": [ { "id": "rs30298179", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs30298179" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "K", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (KES->NES).", "chr_id": "1", "chr_pos": "88205144", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "K16", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "172", "end_pos": "172" } ] }, { "type": "snv", "site_list": [ { "start_pos": "126", "end_pos": "126" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "225", "end_pos": "225" }, { "start_pos": "563", "end_pos": "563" }, { "start_pos": "659", "end_pos": "659" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "169", "end_pos": "169" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "613", "end_pos": "613" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q6PG16-1.225.225", "start_pos": 225, "end_pos": 225, "uniprot_canonical_ac": "Q6PG16-1", "length": 667, "uniprot_id": "HJURP_MOUSE", "protein_name": "Holliday junction recognition protein", "refseq_ac": "NP_766093", "refseq_name": "Holliday junction recognition protein", "gene_name": "Hjurp", "gene_names_uniprotkb": "Hjurp; Fleg1", "gene_names_refseq": "A730008H23Rik; Fleg1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6PG16", "url": "https://www.uniprot.org/uniprotkb/Q6PG16" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388486638", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388486638", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "CPADMAIVARSDGLSLLGTS", "down_seq": "NSVSSQSFEVDDLCNVTISD", "snv": [ { "evidence": [ { "id": "rs3388486638", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388486638" } ], "glycoeffect": [ "n-glyco-sequon-gain", "o-glyco-site-loss" ], "sequence_org": "S", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (SNS->NNS).", "chr_id": "1", "chr_pos": "88194233", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S225", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "172", "end_pos": "172" } ] }, { "type": "snv", "site_list": [ { "start_pos": "126", "end_pos": "126" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "225", "end_pos": "225" }, { "start_pos": "563", "end_pos": "563" }, { "start_pos": "659", "end_pos": "659" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "169", "end_pos": "169" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "613", "end_pos": "613" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q6PG16-1.563.563", "start_pos": 563, "end_pos": 563, "uniprot_canonical_ac": "Q6PG16-1", "length": 667, "uniprot_id": "HJURP_MOUSE", "protein_name": "Holliday junction recognition protein", "refseq_ac": "NP_766093", "refseq_name": "Holliday junction recognition protein", "gene_name": "Hjurp", "gene_names_uniprotkb": "Hjurp; Fleg1", "gene_names_refseq": "A730008H23Rik; Fleg1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6PG16", "url": "https://www.uniprot.org/uniprotkb/Q6PG16" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388487426", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388487426", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "PGCGKDNYYELKKEFNRLYQ", "down_seq": "YCLSPQRAKVTSCGRVSPMK", "snv": [ { "evidence": [ { "id": "rs3388487426", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388487426" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "K", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (KYC->NYC).", "chr_id": "1", "chr_pos": "88193218", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "K563", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "172", "end_pos": "172" } ] }, { "type": "snv", "site_list": [ { "start_pos": "126", "end_pos": "126" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "225", "end_pos": "225" }, { "start_pos": "563", "end_pos": "563" }, { "start_pos": "659", "end_pos": "659" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "169", "end_pos": "169" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "613", "end_pos": "613" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "Q6PG16-1.567.567", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q6PG16-1.659.659", "start_pos": 659, "end_pos": 659, "uniprot_canonical_ac": "Q6PG16-1", "length": 667, "uniprot_id": "HJURP_MOUSE", "protein_name": "Holliday junction recognition protein", "refseq_ac": "NP_766093", "refseq_name": "Holliday junction recognition protein", "gene_name": "Hjurp", "gene_names_uniprotkb": "Hjurp; Fleg1", "gene_names_refseq": "A730008H23Rik; Fleg1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6PG16", "url": "https://www.uniprot.org/uniprotkb/Q6PG16" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs45726911", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs45726911", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "PTKRCKLSYPVACAHQAKFH", "down_seq": "TSGASGWP", "snv": [ { "evidence": [ { "id": "rs45726911", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs45726911" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "D", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (DTS->NTS).", "chr_id": "1", "chr_pos": "88192932", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "D659", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "172", "end_pos": "172" } ] }, { "type": "snv", "site_list": [ { "start_pos": "126", "end_pos": "126" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "225", "end_pos": "225" }, { "start_pos": "563", "end_pos": "563" }, { "start_pos": "659", "end_pos": "659" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "169", "end_pos": "169" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "613", "end_pos": "613" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q6PG16-1.169.169", "start_pos": 169, "end_pos": 169, "uniprot_canonical_ac": "Q6PG16-1", "length": 667, "uniprot_id": "HJURP_MOUSE", "protein_name": "Holliday junction recognition protein", "refseq_ac": "NP_766093", "refseq_name": "Holliday junction recognition protein", "gene_name": "Hjurp", "gene_names_uniprotkb": "Hjurp; Fleg1", "gene_names_refseq": "A730008H23Rik; Fleg1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6PG16", "url": "https://www.uniprot.org/uniprotkb/Q6PG16" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q6PG16", "url": "https://www.uniprot.org/uniprotkb/Q6PG16", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KNAEKRGGKDTVMTWVPSVT", "down_seq": "SVTPASGCQDAISAKSSGGP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q6PG16", "url": "https://www.uniprot.org/uniprotkb/Q6PG16" } ], "site_lbl": "Ser169" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "172", "end_pos": "172" } ] }, { "type": "snv", "site_list": [ { "start_pos": "126", "end_pos": "126" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "225", "end_pos": "225" }, { "start_pos": "563", "end_pos": "563" }, { "start_pos": "659", "end_pos": "659" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "169", "end_pos": "169" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "613", "end_pos": "613" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "Q6PG16-1.172.172", "categories": [ "glycosylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q6PG16-1.185.185", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q6PG16-1.185.185", "start_pos": 185, "end_pos": 185, "uniprot_canonical_ac": "Q6PG16-1", "length": 667, "uniprot_id": "HJURP_MOUSE", "protein_name": "Holliday junction recognition protein", "refseq_ac": "NP_766093", "refseq_name": "Holliday junction recognition protein", "gene_name": "Hjurp", "gene_names_uniprotkb": "Hjurp; Fleg1", "gene_names_refseq": "A730008H23Rik; Fleg1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6PG16", "url": "https://www.uniprot.org/uniprotkb/Q6PG16" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q6PG16", "url": "https://www.uniprot.org/uniprotkb/Q6PG16", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PSVTSSVTPASGCQDAISAK", "down_seq": "SGGPEVSALSSRGQGPSYPC", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q6PG16", "url": "https://www.uniprot.org/uniprotkb/Q6PG16" } ], "site_lbl": "Ser185" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "172", "end_pos": "172" } ] }, { "type": "snv", "site_list": [ { "start_pos": "126", "end_pos": "126" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "225", "end_pos": "225" }, { "start_pos": "563", "end_pos": "563" }, { "start_pos": "659", "end_pos": "659" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "169", "end_pos": "169" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "613", "end_pos": "613" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "Q6PG16-1.169.169", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "Q6PG16-1.172.172", "categories": [ "glycosylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q6PG16-1.195.195", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q6PG16-1.195.195", "start_pos": 195, "end_pos": 195, "uniprot_canonical_ac": "Q6PG16-1", "length": 667, "uniprot_id": "HJURP_MOUSE", "protein_name": "Holliday junction recognition protein", "refseq_ac": "NP_766093", "refseq_name": "Holliday junction recognition protein", "gene_name": "Hjurp", "gene_names_uniprotkb": "Hjurp; Fleg1", "gene_names_refseq": "A730008H23Rik; Fleg1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6PG16", "url": "https://www.uniprot.org/uniprotkb/Q6PG16" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q6PG16", "url": "https://www.uniprot.org/uniprotkb/Q6PG16", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SGCQDAISAKSSGGPEVSAL", "down_seq": "SRGQGPSYPCPADMAIVARS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q6PG16", "url": "https://www.uniprot.org/uniprotkb/Q6PG16" } ], "site_lbl": "Ser195" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "172", "end_pos": "172" } ] }, { "type": "snv", "site_list": [ { "start_pos": "126", "end_pos": "126" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "225", "end_pos": "225" }, { "start_pos": "563", "end_pos": "563" }, { "start_pos": "659", "end_pos": "659" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "169", "end_pos": "169" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "613", "end_pos": "613" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "Q6PG16-1.185.185", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q6PG16-1.388.388", "start_pos": 388, "end_pos": 388, "uniprot_canonical_ac": "Q6PG16-1", "length": 667, "uniprot_id": "HJURP_MOUSE", "protein_name": "Holliday junction recognition protein", "refseq_ac": "NP_766093", "refseq_name": "Holliday junction recognition protein", "gene_name": "Hjurp", "gene_names_uniprotkb": "Hjurp; Fleg1", "gene_names_refseq": "A730008H23Rik; Fleg1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6PG16", "url": "https://www.uniprot.org/uniprotkb/Q6PG16" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q6PG16", "url": "https://www.uniprot.org/uniprotkb/Q6PG16" }, { "database": "iPTMnet", "id": "Q6PG16", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6PG16" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q6PG16", "url": "https://www.uniprot.org/uniprotkb/Q6PG16", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q6PG16", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6PG16", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KDLDLNRERENRVMTLQWLI", "down_seq": "PVKVVPRPRMLPSQVEKWYR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q6PG16", "url": "https://www.uniprot.org/uniprotkb/Q6PG16" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q6PG16", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6PG16" } ], "site_lbl": "Ser388" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "172", "end_pos": "172" } ] }, { "type": "snv", "site_list": [ { "start_pos": "126", "end_pos": "126" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "225", "end_pos": "225" }, { "start_pos": "563", "end_pos": "563" }, { "start_pos": "659", "end_pos": "659" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "169", "end_pos": "169" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "613", "end_pos": "613" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6PG16-1.424.424", "start_pos": 424, "end_pos": 424, "uniprot_canonical_ac": "Q6PG16-1", "length": 667, "uniprot_id": "HJURP_MOUSE", "protein_name": "Holliday junction recognition protein", "refseq_ac": "NP_766093", "refseq_name": "Holliday junction recognition protein", "gene_name": "Hjurp", "gene_names_uniprotkb": "Hjurp; Fleg1", "gene_names_refseq": "A730008H23Rik; Fleg1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6PG16", "url": "https://www.uniprot.org/uniprotkb/Q6PG16" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q6PG16", "url": "https://www.uniprot.org/uniprotkb/Q6PG16", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EKWYREIKIKFDKLHQEYCL", "down_seq": "SGKQPRLTDPTESWAVDVYR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q6PG16", "url": "https://www.uniprot.org/uniprotkb/Q6PG16" } ], "site_lbl": "Ser424" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "172", "end_pos": "172" } ] }, { "type": "snv", "site_list": [ { "start_pos": "126", "end_pos": "126" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "225", "end_pos": "225" }, { "start_pos": "563", "end_pos": "563" }, { "start_pos": "659", "end_pos": "659" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "169", "end_pos": "169" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "613", "end_pos": "613" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q6PG16-1.449.449", "start_pos": 449, "end_pos": 449, "uniprot_canonical_ac": "Q6PG16-1", "length": 667, "uniprot_id": "HJURP_MOUSE", "protein_name": "Holliday junction recognition protein", "refseq_ac": "NP_766093", "refseq_name": "Holliday junction recognition protein", "gene_name": "Hjurp", "gene_names_uniprotkb": "Hjurp; Fleg1", "gene_names_refseq": "A730008H23Rik; Fleg1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6PG16", "url": "https://www.uniprot.org/uniprotkb/Q6PG16" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q6PG16", "url": "https://www.uniprot.org/uniprotkb/Q6PG16", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PRLTDPTESWAVDVYRSGSK", "down_seq": "PGSRQDVETCRPSSPFGREK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q6PG16", "url": "https://www.uniprot.org/uniprotkb/Q6PG16" } ], "site_lbl": "Ser449" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "172", "end_pos": "172" } ] }, { "type": "snv", "site_list": [ { "start_pos": "126", "end_pos": "126" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "225", "end_pos": "225" }, { "start_pos": "563", "end_pos": "563" }, { "start_pos": "659", "end_pos": "659" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "169", "end_pos": "169" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "613", "end_pos": "613" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "upstream", "id": "Q6PG16-1.462.462", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q6PG16-1.462.462", "start_pos": 462, "end_pos": 462, "uniprot_canonical_ac": "Q6PG16-1", "length": 667, "uniprot_id": "HJURP_MOUSE", "protein_name": "Holliday junction recognition protein", "refseq_ac": "NP_766093", "refseq_name": "Holliday junction recognition protein", "gene_name": "Hjurp", "gene_names_uniprotkb": "Hjurp; Fleg1", "gene_names_refseq": "A730008H23Rik; Fleg1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6PG16", "url": "https://www.uniprot.org/uniprotkb/Q6PG16" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q6PG16", "url": "https://www.uniprot.org/uniprotkb/Q6PG16", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VYRSGSKSPGSRQDVETCRP", "down_seq": "SPFGREKTERPGEALEDLRG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q6PG16", "url": "https://www.uniprot.org/uniprotkb/Q6PG16" } ], "site_lbl": "Ser462" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "172", "end_pos": "172" } ] }, { "type": "snv", "site_list": [ { "start_pos": "126", "end_pos": "126" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "225", "end_pos": "225" }, { "start_pos": "563", "end_pos": "563" }, { "start_pos": "659", "end_pos": "659" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "169", "end_pos": "169" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "613", "end_pos": "613" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "Q6PG16-1.449.449", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q6PG16-1.567.567", "start_pos": 567, "end_pos": 567, "uniprot_canonical_ac": "Q6PG16-1", "length": 667, "uniprot_id": "HJURP_MOUSE", "protein_name": "Holliday junction recognition protein", "refseq_ac": "NP_766093", "refseq_name": "Holliday junction recognition protein", "gene_name": "Hjurp", "gene_names_uniprotkb": "Hjurp; Fleg1", "gene_names_refseq": "A730008H23Rik; Fleg1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6PG16", "url": "https://www.uniprot.org/uniprotkb/Q6PG16" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q6PG16", "url": "https://www.uniprot.org/uniprotkb/Q6PG16", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KDNYYELKKEFNRLYQKYCL", "down_seq": "PQRAKVTSCGRVSPMKAAAA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q6PG16", "url": "https://www.uniprot.org/uniprotkb/Q6PG16" } ], "site_lbl": "Ser567" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "172", "end_pos": "172" } ] }, { "type": "snv", "site_list": [ { "start_pos": "126", "end_pos": "126" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "225", "end_pos": "225" }, { "start_pos": "563", "end_pos": "563" }, { "start_pos": "659", "end_pos": "659" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "169", "end_pos": "169" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "613", "end_pos": "613" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "Q6PG16-1.563.563", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q6PG16-1.613.613", "start_pos": 613, "end_pos": 613, "uniprot_canonical_ac": "Q6PG16-1", "length": 667, "uniprot_id": "HJURP_MOUSE", "protein_name": "Holliday junction recognition protein", "refseq_ac": "NP_766093", "refseq_name": "Holliday junction recognition protein", "gene_name": "Hjurp", "gene_names_uniprotkb": "Hjurp; Fleg1", "gene_names_refseq": "A730008H23Rik; Fleg1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6PG16", "url": "https://www.uniprot.org/uniprotkb/Q6PG16" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q6PG16", "url": "https://www.uniprot.org/uniprotkb/Q6PG16", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EHLKRLNPDSPQQSSQKRSI", "down_seq": "PGCHRRVLQDSTAQTASTLV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q6PG16", "url": "https://www.uniprot.org/uniprotkb/Q6PG16" } ], "site_lbl": "Ser613" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "172", "end_pos": "172" } ] }, { "type": "snv", "site_list": [ { "start_pos": "126", "end_pos": "126" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "225", "end_pos": "225" }, { "start_pos": "563", "end_pos": "563" }, { "start_pos": "659", "end_pos": "659" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "169", "end_pos": "169" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "424", "end_pos": "424" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "613", "end_pos": "613" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P41230-1.315.315", "start_pos": 315, "end_pos": 315, "uniprot_canonical_ac": "P41230-1", "length": 1554, "uniprot_id": "KDM5C_MOUSE", "protein_name": "Lysine-specific demethylase 5C", "refseq_ac": "NP_038696", "refseq_name": "lysine-specific demethylase 5C isoform 1", "gene_name": "Kdm5c", "gene_names_uniprotkb": "Kdm5c; Jarid1c; Kiaa0234; Smcx; Xe169", "gene_names_refseq": "D930009K15Rik; Jarid1c; Kdm5c; Smcx; mKIAA0234", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P41230", "url": "https://www.uniprot.org/uniprotkb/P41230" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "KEELSHSPEPCTKMTMRLRR", "down_seq": "HSNAQFIESYVCRMCSRGDE", "glycosylation": [ { "glytoucan_ac": "G95177YH", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "RNHSNAQFIESYVCRMCSR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn315", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "315", "end_pos": "315" } ] }, { "type": "snv", "site_list": [ { "start_pos": "75", "end_pos": "75" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1353", "end_pos": "1353" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "893", "end_pos": "893" }, { "start_pos": "897", "end_pos": "897" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "P41230-1.301.301", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P41230-1.317.317", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P41230-1.75.75", "start_pos": 75, "end_pos": 75, "uniprot_canonical_ac": "P41230-1", "length": 1554, "uniprot_id": "KDM5C_MOUSE", "protein_name": "Lysine-specific demethylase 5C", "refseq_ac": "NP_038696", "refseq_name": "lysine-specific demethylase 5C isoform 1", "gene_name": "Kdm5c", "gene_names_uniprotkb": "Kdm5c; Jarid1c; Kiaa0234; Smcx; Xe169", "gene_names_refseq": "D930009K15Rik; Jarid1c; Kdm5c; Smcx; mKIAA0234", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P41230", "url": "https://www.uniprot.org/uniprotkb/P41230" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3412750249", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3412750249", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "L", "start_aa": "L", "up_seq": "PFAVEVDNFRFTPRIQRLNE", "down_seq": "EAQTRVKLNYLDQIAKFWEI", "snv": [ { "evidence": [ { "id": "rs3412750249", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3412750249" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "L", "sequence_mut": "S", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (NEL->NES).", "chr_id": "X", "chr_pos": "151053523", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "L75", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "315", "end_pos": "315" } ] }, { "type": "snv", "site_list": [ { "start_pos": "75", "end_pos": "75" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1353", "end_pos": "1353" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "893", "end_pos": "893" }, { "start_pos": "897", "end_pos": "897" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P41230-1.1353.1353", "start_pos": 1353, "end_pos": 1353, "uniprot_canonical_ac": "P41230-1", "length": 1554, "uniprot_id": "KDM5C_MOUSE", "protein_name": "Lysine-specific demethylase 5C", "refseq_ac": "NP_038696", "refseq_name": "lysine-specific demethylase 5C isoform 1", "gene_name": "Kdm5c", "gene_names_uniprotkb": "Kdm5c; Jarid1c; Kiaa0234; Smcx; Xe169", "gene_names_refseq": "D930009K15Rik; Jarid1c; Kdm5c; Smcx; mKIAA0234", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P41230", "url": "https://www.uniprot.org/uniprotkb/P41230" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P41230", "url": "https://www.uniprot.org/uniprotkb/P41230", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EGTGNMPKVQGLLENGDSVT", "down_seq": "PEKVATEEGSGKRDLELLSS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P41230", "url": "https://www.uniprot.org/uniprotkb/P41230" } ], "site_lbl": "Ser1353" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "315", "end_pos": "315" } ] }, { "type": "snv", "site_list": [ { "start_pos": "75", "end_pos": "75" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1353", "end_pos": "1353" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "893", "end_pos": "893" }, { "start_pos": "897", "end_pos": "897" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P41230-1.287.287", "start_pos": 287, "end_pos": 287, "uniprot_canonical_ac": "P41230-1", "length": 1554, "uniprot_id": "KDM5C_MOUSE", "protein_name": "Lysine-specific demethylase 5C", "refseq_ac": "NP_038696", "refseq_name": "lysine-specific demethylase 5C isoform 1", "gene_name": "Kdm5c", "gene_names_uniprotkb": "Kdm5c; Jarid1c; Kiaa0234; Smcx; Xe169", "gene_names_refseq": "D930009K15Rik; Jarid1c; Kdm5c; Smcx; mKIAA0234", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P41230", "url": "https://www.uniprot.org/uniprotkb/P41230" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P41230", "url": "https://www.uniprot.org/uniprotkb/P41230", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "CPPTVVVKEELGGDVKMEST", "down_seq": "PKTFLEGKEELSHSPEPCTK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P41230", "url": "https://www.uniprot.org/uniprotkb/P41230" } ], "site_lbl": "Ser287" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "315", "end_pos": "315" } ] }, { "type": "snv", "site_list": [ { "start_pos": "75", "end_pos": "75" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1353", "end_pos": "1353" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "893", "end_pos": "893" }, { "start_pos": "897", "end_pos": "897" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "upstream", "id": "P41230-1.301.301", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P41230-1.301.301", "start_pos": 301, "end_pos": 301, "uniprot_canonical_ac": "P41230-1", "length": 1554, "uniprot_id": "KDM5C_MOUSE", "protein_name": "Lysine-specific demethylase 5C", "refseq_ac": "NP_038696", "refseq_name": "lysine-specific demethylase 5C isoform 1", "gene_name": "Kdm5c", "gene_names_uniprotkb": "Kdm5c; Jarid1c; Kiaa0234; Smcx; Xe169", "gene_names_refseq": "D930009K15Rik; Jarid1c; Kdm5c; Smcx; mKIAA0234", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P41230", "url": "https://www.uniprot.org/uniprotkb/P41230" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P41230", "url": "https://www.uniprot.org/uniprotkb/P41230", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VKMESTSPKTFLEGKEELSH", "down_seq": "PEPCTKMTMRLRRNHSNAQF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P41230", "url": "https://www.uniprot.org/uniprotkb/P41230" } ], "site_lbl": "Ser301" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "315", "end_pos": "315" } ] }, { "type": "snv", "site_list": [ { "start_pos": "75", "end_pos": "75" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1353", "end_pos": "1353" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "893", "end_pos": "893" }, { "start_pos": "897", "end_pos": "897" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "P41230-1.287.287", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P41230-1.315.315", "categories": [ "glycosylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P41230-1.317.317", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P41230-1.317.317", "start_pos": 317, "end_pos": 317, "uniprot_canonical_ac": "P41230-1", "length": 1554, "uniprot_id": "KDM5C_MOUSE", "protein_name": "Lysine-specific demethylase 5C", "refseq_ac": "NP_038696", "refseq_name": "lysine-specific demethylase 5C isoform 1", "gene_name": "Kdm5c", "gene_names_uniprotkb": "Kdm5c; Jarid1c; Kiaa0234; Smcx; Xe169", "gene_names_refseq": "D930009K15Rik; Jarid1c; Kdm5c; Smcx; mKIAA0234", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P41230", "url": "https://www.uniprot.org/uniprotkb/P41230" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P41230", "url": "https://www.uniprot.org/uniprotkb/P41230" }, { "database": "iPTMnet", "id": "P41230", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41230" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "P41230", "url": "https://www.uniprot.org/uniprotkb/P41230", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P41230", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41230", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ELSHSPEPCTKMTMRLRRNH", "down_seq": "NAQFIESYVCRMCSRGDEDD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P41230", "url": "https://www.uniprot.org/uniprotkb/P41230" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "P41230", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41230" } ], "site_lbl": "Ser317" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "315", "end_pos": "315" } ] }, { "type": "snv", "site_list": [ { "start_pos": "75", "end_pos": "75" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1353", "end_pos": "1353" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "893", "end_pos": "893" }, { "start_pos": "897", "end_pos": "897" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P41230-1.301.301", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P41230-1.315.315", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P41230-1.893.893", "start_pos": 893, "end_pos": 893, "uniprot_canonical_ac": "P41230-1", "length": 1554, "uniprot_id": "KDM5C_MOUSE", "protein_name": "Lysine-specific demethylase 5C", "refseq_ac": "NP_038696", "refseq_name": "lysine-specific demethylase 5C isoform 1", "gene_name": "Kdm5c", "gene_names_uniprotkb": "Kdm5c; Jarid1c; Kiaa0234; Smcx; Xe169", "gene_names_refseq": "D930009K15Rik; Jarid1c; Kdm5c; Smcx; mKIAA0234", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P41230", "url": "https://www.uniprot.org/uniprotkb/P41230" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P41230", "url": "https://www.uniprot.org/uniprotkb/P41230" }, { "database": "iPTMnet", "id": "P41230", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41230" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "P41230", "url": "https://www.uniprot.org/uniprotkb/P41230", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P41230", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41230", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VKGILEQVEAYQTEAREALV", "down_seq": "QPSSPGLLQSLLERGQQLGV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P41230", "url": "https://www.uniprot.org/uniprotkb/P41230" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "P41230", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41230" } ], "site_lbl": "Ser893" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "315", "end_pos": "315" } ] }, { "type": "snv", "site_list": [ { "start_pos": "75", "end_pos": "75" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1353", "end_pos": "1353" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "893", "end_pos": "893" }, { "start_pos": "897", "end_pos": "897" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "P41230-1.897.897", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P41230-1.897.897", "start_pos": 897, "end_pos": 897, "uniprot_canonical_ac": "P41230-1", "length": 1554, "uniprot_id": "KDM5C_MOUSE", "protein_name": "Lysine-specific demethylase 5C", "refseq_ac": "NP_038696", "refseq_name": "lysine-specific demethylase 5C isoform 1", "gene_name": "Kdm5c", "gene_names_uniprotkb": "Kdm5c; Jarid1c; Kiaa0234; Smcx; Xe169", "gene_names_refseq": "D930009K15Rik; Jarid1c; Kdm5c; Smcx; mKIAA0234", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P41230", "url": "https://www.uniprot.org/uniprotkb/P41230" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P41230", "url": "https://www.uniprot.org/uniprotkb/P41230", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LEQVEAYQTEAREALVSQPS", "down_seq": "PGLLQSLLERGQQLGVEVPE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P41230", "url": "https://www.uniprot.org/uniprotkb/P41230" } ], "site_lbl": "Ser897" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "315", "end_pos": "315" } ] }, { "type": "snv", "site_list": [ { "start_pos": "75", "end_pos": "75" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1353", "end_pos": "1353" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "893", "end_pos": "893" }, { "start_pos": "897", "end_pos": "897" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "P41230-1.893.893", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9ESN9-1.266.266", "start_pos": 266, "end_pos": 266, "uniprot_canonical_ac": "Q9ESN9-1", "length": 1337, "uniprot_id": "JIP3_MOUSE", "protein_name": "C-Jun-amino-terminal kinase-interacting protein 3", "refseq_ac": "NP_001156919", "refseq_name": "C-Jun-amino-terminal kinase-interacting protein 3 isoform b", "gene_name": "Mapk8ip3", "gene_names_uniprotkb": "Mapk8ip3; Jip3; Jsap1; Syd2", "gene_names_refseq": "D17Wsu15e; JIP-3; JSAP1a; JSAP1b; JSAP1c; JSAP1d; JSAP1; Jip3; Mapk8ip3; Syd2; mKIAA1066", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Interaction of a mitogen-activated protein kinase signaling module with the neuronal protein JIP3.", "journal": "Molecular and cellular biology", "date": "2000", "authors": "Kelkar N, Gupta S, Dickens M, Davis RJ", "evidence": [ { "database": "UniProtKB", "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9" }, { "database": "iPTMnet", "id": "Q9ESN9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ESN9" } ], "reference": [ { "type": "PubMed", "id": "10629060", "url": "https://glygen.org/publication/PubMed/10629060" } ] } ], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10629060", "url": "https://glygen.org/publication/PubMed/10629060", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9ESN9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ESN9", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "SSYQCPNDEMSESGQSSAAA", "down_seq": "PSTTGTKSNTPTSSVPSAAV", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr266", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Results in loss of phosphorylation of MAPK8IP3; when associated with A-276 and A-287. Does not effect binding of components of the JNK pathway.", "evidence": [ { "database": "UniProtKB", "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9" }, { "database": "PubMed", "id": "10629060", "url": "https://glygen.org/publication/PubMed/10629060" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine; by MAPK", "evidence": [ { "database": "UniProtKB", "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9" }, { "database": "iPTMnet", "id": "Q9ESN9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ESN9" }, { "database": "PubMed", "id": "10629060", "url": "https://glygen.org/publication/PubMed/10629060" } ], "site_lbl": "Thr266" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "266", "end_pos": "266" }, { "start_pos": "368", "end_pos": "368" }, { "start_pos": "715", "end_pos": "715" }, { "start_pos": "931", "end_pos": "931" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "205", "end_pos": "205" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "287", "end_pos": "287" } ] }, { "type": "snv", "site_list": [ { "start_pos": "889", "end_pos": "889" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "266", "end_pos": "266" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "365", "end_pos": "365" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "603", "end_pos": "603" }, { "start_pos": "677", "end_pos": "677" } ] } ], "categories": [ "glycosylation_flag", "mutagenesis_flag", "phosphorylation_flag" ], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "upstream", "id": "Q9ESN9-1.276.276", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9ESN9-1.368.368", "start_pos": 368, "end_pos": 368, "uniprot_canonical_ac": "Q9ESN9-1", "length": 1337, "uniprot_id": "JIP3_MOUSE", "protein_name": "C-Jun-amino-terminal kinase-interacting protein 3", "refseq_ac": "NP_001156919", "refseq_name": "C-Jun-amino-terminal kinase-interacting protein 3 isoform b", "gene_name": "Mapk8ip3", "gene_names_uniprotkb": "Mapk8ip3; Jip3; Jsap1; Syd2", "gene_names_refseq": "D17Wsu15e; JIP-3; JSAP1a; JSAP1b; JSAP1c; JSAP1d; JSAP1; Jip3; Mapk8ip3; Syd2; mKIAA1066", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "STPELDVCPETRLERTGSSP", "down_seq": "QGIVNKAFGINTDSLYHELS", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr368", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "266", "end_pos": "266" }, { "start_pos": "368", "end_pos": "368" }, { "start_pos": "715", "end_pos": "715" }, { "start_pos": "931", "end_pos": "931" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "205", "end_pos": "205" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "287", "end_pos": "287" } ] }, { "type": "snv", "site_list": [ { "start_pos": "889", "end_pos": "889" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "266", "end_pos": "266" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "365", "end_pos": "365" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "603", "end_pos": "603" }, { "start_pos": "677", "end_pos": "677" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "Q9ESN9-1.365.365", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q9ESN9-1.366.366", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9ESN9-1.715.715", "start_pos": 715, "end_pos": 715, "uniprot_canonical_ac": "Q9ESN9-1", "length": 1337, "uniprot_id": "JIP3_MOUSE", "protein_name": "C-Jun-amino-terminal kinase-interacting protein 3", "refseq_ac": "NP_001156919", "refseq_name": "C-Jun-amino-terminal kinase-interacting protein 3 isoform b", "gene_name": "Mapk8ip3", "gene_names_uniprotkb": "Mapk8ip3; Jip3; Jsap1; Syd2", "gene_names_refseq": "D17Wsu15e; JIP-3; JSAP1a; JSAP1b; JSAP1c; JSAP1d; JSAP1; Jip3; Mapk8ip3; Syd2; mKIAA1066", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Capturing site-specific heterogeneity with large-scale N-glycoproteome analysis.", "journal": "Nature communications", "date": "2019", "authors": "Riley NM, Hebert AS, Westphall MS, Coon JJ", "evidence": [ { "database": "GlyConnect", "id": "2216", "url": "https://glyconnect.expasy.org/browser/proteins/2216" } ], "reference": [ { "type": "PubMed", "id": "30899004", "url": "https://glygen.org/publication/PubMed/30899004" } ] } ], "crossref": [ { "id": "30899004", "url": "https://glygen.org/publication/PubMed/30899004", "database": "PubMed", "categories": [ "Other" ] }, { "id": "2216", "url": "https://glyconnect.expasy.org/browser/proteins/2216", "database": "GlyConnect", "categories": [ "Glycomics", "Glycoproteomics" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "YCRPLVEKDPSTKLWCAAGV", "down_seq": "LSGWKPHEEDSSNGPKPVPG", "glycosylation": [ { "glytoucan_ac": "G63628AV", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn715", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2216", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2216" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "266", "end_pos": "266" }, { "start_pos": "368", "end_pos": "368" }, { "start_pos": "715", "end_pos": "715" }, { "start_pos": "931", "end_pos": "931" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "205", "end_pos": "205" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "287", "end_pos": "287" } ] }, { "type": "snv", "site_list": [ { "start_pos": "889", "end_pos": "889" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "266", "end_pos": "266" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "365", "end_pos": "365" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "603", "end_pos": "603" }, { "start_pos": "677", "end_pos": "677" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9ESN9-1.931.931", "start_pos": 931, "end_pos": 931, "uniprot_canonical_ac": "Q9ESN9-1", "length": 1337, "uniprot_id": "JIP3_MOUSE", "protein_name": "C-Jun-amino-terminal kinase-interacting protein 3", "refseq_ac": "NP_001156919", "refseq_name": "C-Jun-amino-terminal kinase-interacting protein 3 isoform b", "gene_name": "Mapk8ip3", "gene_names_uniprotkb": "Mapk8ip3; Jip3; Jsap1; Syd2", "gene_names_refseq": "D17Wsu15e; JIP-3; JSAP1a; JSAP1b; JSAP1c; JSAP1d; JSAP1; Jip3; Mapk8ip3; Syd2; mKIAA1066", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "EATTVRPGPLTEHVFTDPAP", "down_seq": "PSSSTQPASENGSESNGTIV", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr931", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "266", "end_pos": "266" }, { "start_pos": "368", "end_pos": "368" }, { "start_pos": "715", "end_pos": "715" }, { "start_pos": "931", "end_pos": "931" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "205", "end_pos": "205" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "287", "end_pos": "287" } ] }, { "type": "snv", "site_list": [ { "start_pos": "889", "end_pos": "889" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "266", "end_pos": "266" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "365", "end_pos": "365" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "603", "end_pos": "603" }, { "start_pos": "677", "end_pos": "677" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9ESN9-1.205.205", "start_pos": 205, "end_pos": 205, "uniprot_canonical_ac": "Q9ESN9-1", "length": 1337, "uniprot_id": "JIP3_MOUSE", "protein_name": "C-Jun-amino-terminal kinase-interacting protein 3", "refseq_ac": "NP_001156919", "refseq_name": "C-Jun-amino-terminal kinase-interacting protein 3 isoform b", "gene_name": "Mapk8ip3", "gene_names_uniprotkb": "Mapk8ip3; Jip3; Jsap1; Syd2", "gene_names_refseq": "D17Wsu15e; JIP-3; JSAP1a; JSAP1b; JSAP1c; JSAP1d; JSAP1; Jip3; Mapk8ip3; Syd2; mKIAA1066", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Interaction of a mitogen-activated protein kinase signaling module with the neuronal protein JIP3.", "journal": "Molecular and cellular biology", "date": "2000", "authors": "Kelkar N, Gupta S, Dickens M, Davis RJ", "evidence": [ { "database": "UniProtKB", "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9" }, { "database": "iPTMnet", "id": "Q9ESN9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ESN9" } ], "reference": [ { "type": "PubMed", "id": "10629060", "url": "https://glygen.org/publication/PubMed/10629060" } ] } ], "crossref": [ { "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10629060", "url": "https://glygen.org/publication/PubMed/10629060", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "QQVGGSGQTESSLPGRSRKE", "down_seq": "PTSLNVFPLADGMVRAQMGG", "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "G", "comment": "Results in inhibition of JNK binding.", "evidence": [ { "database": "UniProtKB", "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9" }, { "database": "PubMed", "id": "10629060", "url": "https://glygen.org/publication/PubMed/10629060" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "266", "end_pos": "266" }, { "start_pos": "368", "end_pos": "368" }, { "start_pos": "715", "end_pos": "715" }, { "start_pos": "931", "end_pos": "931" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "205", "end_pos": "205" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "287", "end_pos": "287" } ] }, { "type": "snv", "site_list": [ { "start_pos": "889", "end_pos": "889" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "266", "end_pos": "266" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "365", "end_pos": "365" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "603", "end_pos": "603" }, { "start_pos": "677", "end_pos": "677" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "Q9ESN9-1.206.206", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q9ESN9-1.207.207", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q9ESN9-1.208.208", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q9ESN9-1.209.209", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9ESN9-1.206.206", "start_pos": 206, "end_pos": 206, "uniprot_canonical_ac": "Q9ESN9-1", "length": 1337, "uniprot_id": "JIP3_MOUSE", "protein_name": "C-Jun-amino-terminal kinase-interacting protein 3", "refseq_ac": "NP_001156919", "refseq_name": "C-Jun-amino-terminal kinase-interacting protein 3 isoform b", "gene_name": "Mapk8ip3", "gene_names_uniprotkb": "Mapk8ip3; Jip3; Jsap1; Syd2", "gene_names_refseq": "D17Wsu15e; JIP-3; JSAP1a; JSAP1b; JSAP1c; JSAP1d; JSAP1; Jip3; Mapk8ip3; Syd2; mKIAA1066", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Interaction of a mitogen-activated protein kinase signaling module with the neuronal protein JIP3.", "journal": "Molecular and cellular biology", "date": "2000", "authors": "Kelkar N, Gupta S, Dickens M, Davis RJ", "evidence": [ { "database": "UniProtKB", "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9" }, { "database": "iPTMnet", "id": "Q9ESN9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ESN9" } ], "reference": [ { "type": "PubMed", "id": "10629060", "url": "https://glygen.org/publication/PubMed/10629060" } ] } ], "crossref": [ { "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10629060", "url": "https://glygen.org/publication/PubMed/10629060", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "P", "start_aa": "P", "up_seq": "QVGGSGQTESSLPGRSRKER", "down_seq": "TSLNVFPLADGMVRAQMGGK", "mutagenesis": [ { "sequence_org": "P", "sequence_mut": "G", "comment": "Results in inhibition of JNK binding.", "evidence": [ { "database": "UniProtKB", "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9" }, { "database": "PubMed", "id": "10629060", "url": "https://glygen.org/publication/PubMed/10629060" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "266", "end_pos": "266" }, { "start_pos": "368", "end_pos": "368" }, { "start_pos": "715", "end_pos": "715" }, { "start_pos": "931", "end_pos": "931" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "205", "end_pos": "205" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "287", "end_pos": "287" } ] }, { "type": "snv", "site_list": [ { "start_pos": "889", "end_pos": "889" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "266", "end_pos": "266" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "365", "end_pos": "365" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "603", "end_pos": "603" }, { "start_pos": "677", "end_pos": "677" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "Q9ESN9-1.205.205", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q9ESN9-1.207.207", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q9ESN9-1.208.208", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q9ESN9-1.209.209", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9ESN9-1.207.207", "start_pos": 207, "end_pos": 207, "uniprot_canonical_ac": "Q9ESN9-1", "length": 1337, "uniprot_id": "JIP3_MOUSE", "protein_name": "C-Jun-amino-terminal kinase-interacting protein 3", "refseq_ac": "NP_001156919", "refseq_name": "C-Jun-amino-terminal kinase-interacting protein 3 isoform b", "gene_name": "Mapk8ip3", "gene_names_uniprotkb": "Mapk8ip3; Jip3; Jsap1; Syd2", "gene_names_refseq": "D17Wsu15e; JIP-3; JSAP1a; JSAP1b; JSAP1c; JSAP1d; JSAP1; Jip3; Mapk8ip3; Syd2; mKIAA1066", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Interaction of a mitogen-activated protein kinase signaling module with the neuronal protein JIP3.", "journal": "Molecular and cellular biology", "date": "2000", "authors": "Kelkar N, Gupta S, Dickens M, Davis RJ", "evidence": [ { "database": "UniProtKB", "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9" }, { "database": "iPTMnet", "id": "Q9ESN9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ESN9" } ], "reference": [ { "type": "PubMed", "id": "10629060", "url": "https://glygen.org/publication/PubMed/10629060" } ] } ], "crossref": [ { "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10629060", "url": "https://glygen.org/publication/PubMed/10629060", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "VGGSGQTESSLPGRSRKERP", "down_seq": "SLNVFPLADGMVRAQMGGKL", "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "G", "comment": "Results in inhibition of JNK binding.", "evidence": [ { "database": "UniProtKB", "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9" }, { "database": "PubMed", "id": "10629060", "url": "https://glygen.org/publication/PubMed/10629060" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "266", "end_pos": "266" }, { "start_pos": "368", "end_pos": "368" }, { "start_pos": "715", "end_pos": "715" }, { "start_pos": "931", "end_pos": "931" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "205", "end_pos": "205" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "287", "end_pos": "287" } ] }, { "type": "snv", "site_list": [ { "start_pos": "889", "end_pos": "889" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "266", "end_pos": "266" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "365", "end_pos": "365" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "603", "end_pos": "603" }, { "start_pos": "677", "end_pos": "677" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "Q9ESN9-1.205.205", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q9ESN9-1.206.206", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q9ESN9-1.208.208", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q9ESN9-1.209.209", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9ESN9-1.208.208", "start_pos": 208, "end_pos": 208, "uniprot_canonical_ac": "Q9ESN9-1", "length": 1337, "uniprot_id": "JIP3_MOUSE", "protein_name": "C-Jun-amino-terminal kinase-interacting protein 3", "refseq_ac": "NP_001156919", "refseq_name": "C-Jun-amino-terminal kinase-interacting protein 3 isoform b", "gene_name": "Mapk8ip3", "gene_names_uniprotkb": "Mapk8ip3; Jip3; Jsap1; Syd2", "gene_names_refseq": "D17Wsu15e; JIP-3; JSAP1a; JSAP1b; JSAP1c; JSAP1d; JSAP1; Jip3; Mapk8ip3; Syd2; mKIAA1066", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Interaction of a mitogen-activated protein kinase signaling module with the neuronal protein JIP3.", "journal": "Molecular and cellular biology", "date": "2000", "authors": "Kelkar N, Gupta S, Dickens M, Davis RJ", "evidence": [ { "database": "UniProtKB", "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9" }, { "database": "iPTMnet", "id": "Q9ESN9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ESN9" } ], "reference": [ { "type": "PubMed", "id": "10629060", "url": "https://glygen.org/publication/PubMed/10629060" } ] } ], "crossref": [ { "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10629060", "url": "https://glygen.org/publication/PubMed/10629060", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GGSGQTESSLPGRSRKERPT", "down_seq": "LNVFPLADGMVRAQMGGKLV", "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "G", "comment": "Results in inhibition of JNK binding.", "evidence": [ { "database": "UniProtKB", "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9" }, { "database": "PubMed", "id": "10629060", "url": "https://glygen.org/publication/PubMed/10629060" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "266", "end_pos": "266" }, { "start_pos": "368", "end_pos": "368" }, { "start_pos": "715", "end_pos": "715" }, { "start_pos": "931", "end_pos": "931" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "205", "end_pos": "205" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "287", "end_pos": "287" } ] }, { "type": "snv", "site_list": [ { "start_pos": "889", "end_pos": "889" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "266", "end_pos": "266" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "365", "end_pos": "365" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "603", "end_pos": "603" }, { "start_pos": "677", "end_pos": "677" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "Q9ESN9-1.205.205", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q9ESN9-1.206.206", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q9ESN9-1.207.207", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q9ESN9-1.209.209", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9ESN9-1.209.209", "start_pos": 209, "end_pos": 209, "uniprot_canonical_ac": "Q9ESN9-1", "length": 1337, "uniprot_id": "JIP3_MOUSE", "protein_name": "C-Jun-amino-terminal kinase-interacting protein 3", "refseq_ac": "NP_001156919", "refseq_name": "C-Jun-amino-terminal kinase-interacting protein 3 isoform b", "gene_name": "Mapk8ip3", "gene_names_uniprotkb": "Mapk8ip3; Jip3; Jsap1; Syd2", "gene_names_refseq": "D17Wsu15e; JIP-3; JSAP1a; JSAP1b; JSAP1c; JSAP1d; JSAP1; Jip3; Mapk8ip3; Syd2; mKIAA1066", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Interaction of a mitogen-activated protein kinase signaling module with the neuronal protein JIP3.", "journal": "Molecular and cellular biology", "date": "2000", "authors": "Kelkar N, Gupta S, Dickens M, Davis RJ", "evidence": [ { "database": "UniProtKB", "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9" }, { "database": "iPTMnet", "id": "Q9ESN9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ESN9" } ], "reference": [ { "type": "PubMed", "id": "10629060", "url": "https://glygen.org/publication/PubMed/10629060" } ] } ], "crossref": [ { "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10629060", "url": "https://glygen.org/publication/PubMed/10629060", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "L", "start_aa": "L", "up_seq": "GSGQTESSLPGRSRKERPTS", "down_seq": "NVFPLADGMVRAQMGGKLVP", "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "G", "comment": "Results in inhibition of JNK binding.", "evidence": [ { "database": "UniProtKB", "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9" }, { "database": "PubMed", "id": "10629060", "url": "https://glygen.org/publication/PubMed/10629060" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "266", "end_pos": "266" }, { "start_pos": "368", "end_pos": "368" }, { "start_pos": "715", "end_pos": "715" }, { "start_pos": "931", "end_pos": "931" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "205", "end_pos": "205" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "287", "end_pos": "287" } ] }, { "type": "snv", "site_list": [ { "start_pos": "889", "end_pos": "889" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "266", "end_pos": "266" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "365", "end_pos": "365" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "603", "end_pos": "603" }, { "start_pos": "677", "end_pos": "677" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "Q9ESN9-1.205.205", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q9ESN9-1.206.206", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q9ESN9-1.207.207", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q9ESN9-1.208.208", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9ESN9-1.276.276", "start_pos": 276, "end_pos": 276, "uniprot_canonical_ac": "Q9ESN9-1", "length": 1337, "uniprot_id": "JIP3_MOUSE", "protein_name": "C-Jun-amino-terminal kinase-interacting protein 3", "refseq_ac": "NP_001156919", "refseq_name": "C-Jun-amino-terminal kinase-interacting protein 3 isoform b", "gene_name": "Mapk8ip3", "gene_names_uniprotkb": "Mapk8ip3; Jip3; Jsap1; Syd2", "gene_names_refseq": "D17Wsu15e; JIP-3; JSAP1a; JSAP1b; JSAP1c; JSAP1d; JSAP1; Jip3; Mapk8ip3; Syd2; mKIAA1066", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Interaction of a mitogen-activated protein kinase signaling module with the neuronal protein JIP3.", "journal": "Molecular and cellular biology", "date": "2000", "authors": "Kelkar N, Gupta S, Dickens M, Davis RJ", "evidence": [ { "database": "UniProtKB", "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9" }, { "database": "iPTMnet", "id": "Q9ESN9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ESN9" } ], "reference": [ { "type": "PubMed", "id": "10629060", "url": "https://glygen.org/publication/PubMed/10629060" } ] } ], "crossref": [ { "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10629060", "url": "https://glygen.org/publication/PubMed/10629060", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9ESN9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ESN9", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "SESGQSSAAATPSTTGTKSN", "down_seq": "PTSSVPSAAVTPLNESLQPL", "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Results in loss of phosphorylation of MAPK8IP3; when associated with A-266 and A-287. Does not effect binding of components of the JNK pathway.", "evidence": [ { "database": "UniProtKB", "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9" }, { "database": "PubMed", "id": "10629060", "url": "https://glygen.org/publication/PubMed/10629060" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine; by MAPK", "evidence": [ { "database": "UniProtKB", "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9" }, { "database": "iPTMnet", "id": "Q9ESN9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ESN9" }, { "database": "PubMed", "id": "10629060", "url": "https://glygen.org/publication/PubMed/10629060" } ], "site_lbl": "Thr276" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "266", "end_pos": "266" }, { "start_pos": "368", "end_pos": "368" }, { "start_pos": "715", "end_pos": "715" }, { "start_pos": "931", "end_pos": "931" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "205", "end_pos": "205" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "287", "end_pos": "287" } ] }, { "type": "snv", "site_list": [ { "start_pos": "889", "end_pos": "889" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "266", "end_pos": "266" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "365", "end_pos": "365" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "603", "end_pos": "603" }, { "start_pos": "677", "end_pos": "677" } ] } ], "categories": [ "mutagenesis_flag", "phosphorylation_flag" ], "glycosylation": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "Q9ESN9-1.266.266", "categories": [ "glycosylation_flag", "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q9ESN9-1.287.287", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9ESN9-1.287.287", "start_pos": 287, "end_pos": 287, "uniprot_canonical_ac": "Q9ESN9-1", "length": 1337, "uniprot_id": "JIP3_MOUSE", "protein_name": "C-Jun-amino-terminal kinase-interacting protein 3", "refseq_ac": "NP_001156919", "refseq_name": "C-Jun-amino-terminal kinase-interacting protein 3 isoform b", "gene_name": "Mapk8ip3", "gene_names_uniprotkb": "Mapk8ip3; Jip3; Jsap1; Syd2", "gene_names_refseq": "D17Wsu15e; JIP-3; JSAP1a; JSAP1b; JSAP1c; JSAP1d; JSAP1; Jip3; Mapk8ip3; Syd2; mKIAA1066", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Interaction of a mitogen-activated protein kinase signaling module with the neuronal protein JIP3.", "journal": "Molecular and cellular biology", "date": "2000", "authors": "Kelkar N, Gupta S, Dickens M, Davis RJ", "evidence": [ { "database": "UniProtKB", "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9" }, { "database": "iPTMnet", "id": "Q9ESN9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ESN9" } ], "reference": [ { "type": "PubMed", "id": "10629060", "url": "https://glygen.org/publication/PubMed/10629060" } ] }, { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9" }, { "database": "iPTMnet", "id": "Q9ESN9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ESN9" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10629060", "url": "https://glygen.org/publication/PubMed/10629060", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9ESN9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ESN9", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "PSTTGTKSNTPTSSVPSAAV", "down_seq": "PLNESLQPLGDYVSVTKNNK", "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Results in loss of phosphorylation of MAPK8IP3; when associated with A-266 and A-287. Does not effect binding of components of the JNK pathway.", "evidence": [ { "database": "UniProtKB", "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9" }, { "database": "PubMed", "id": "10629060", "url": "https://glygen.org/publication/PubMed/10629060" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine; by MAPK", "evidence": [ { "database": "UniProtKB", "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9" }, { "database": "iPTMnet", "id": "Q9ESN9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ESN9" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "PubMed", "id": "10629060", "url": "https://glygen.org/publication/PubMed/10629060" } ], "site_lbl": "Thr287" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "266", "end_pos": "266" }, { "start_pos": "368", "end_pos": "368" }, { "start_pos": "715", "end_pos": "715" }, { "start_pos": "931", "end_pos": "931" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "205", "end_pos": "205" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "287", "end_pos": "287" } ] }, { "type": "snv", "site_list": [ { "start_pos": "889", "end_pos": "889" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "266", "end_pos": "266" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "365", "end_pos": "365" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "603", "end_pos": "603" }, { "start_pos": "677", "end_pos": "677" } ] } ], "categories": [ "mutagenesis_flag", "phosphorylation_flag" ], "glycosylation": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "Q9ESN9-1.276.276", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9ESN9-1.889.889", "start_pos": 889, "end_pos": 889, "uniprot_canonical_ac": "Q9ESN9-1", "length": 1337, "uniprot_id": "JIP3_MOUSE", "protein_name": "C-Jun-amino-terminal kinase-interacting protein 3", "refseq_ac": "NP_001156919", "refseq_name": "C-Jun-amino-terminal kinase-interacting protein 3 isoform b", "gene_name": "Mapk8ip3", "gene_names_uniprotkb": "Mapk8ip3; Jip3; Jsap1; Syd2", "gene_names_refseq": "D17Wsu15e; JIP-3; JSAP1a; JSAP1b; JSAP1c; JSAP1d; JSAP1; Jip3; Mapk8ip3; Syd2; mKIAA1066", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3389440349", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389440349", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "P", "start_aa": "P", "up_seq": "TPVLDKGQGDVATTANGKVN", "down_seq": "SQSTEEATEATEVPDPGPSE", "snv": [ { "evidence": [ { "id": "rs3389440349", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389440349" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "P", "sequence_mut": "L", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (NPS->NLS).", "chr_id": "17", "chr_pos": "25120467", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "P889", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "266", "end_pos": "266" }, { "start_pos": "368", "end_pos": "368" }, { "start_pos": "715", "end_pos": "715" }, { "start_pos": "931", "end_pos": "931" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "205", "end_pos": "205" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "287", "end_pos": "287" } ] }, { "type": "snv", "site_list": [ { "start_pos": "889", "end_pos": "889" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "266", "end_pos": "266" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "365", "end_pos": "365" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "603", "end_pos": "603" }, { "start_pos": "677", "end_pos": "677" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9ESN9-1.315.315", "start_pos": 315, "end_pos": 315, "uniprot_canonical_ac": "Q9ESN9-1", "length": 1337, "uniprot_id": "JIP3_MOUSE", "protein_name": "C-Jun-amino-terminal kinase-interacting protein 3", "refseq_ac": "NP_001156919", "refseq_name": "C-Jun-amino-terminal kinase-interacting protein 3 isoform b", "gene_name": "Mapk8ip3", "gene_names_uniprotkb": "Mapk8ip3; Jip3; Jsap1; Syd2", "gene_names_refseq": "D17Wsu15e; JIP-3; JSAP1a; JSAP1b; JSAP1c; JSAP1d; JSAP1; Jip3; Mapk8ip3; Syd2; mKIAA1066", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PLGDYVSVTKNNKQAREKRN", "down_seq": "RNMEVQVTQEMRNVSIGMGS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by ROCK1", "evidence": [ { "database": "UniProtKB", "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9" } ], "site_lbl": "Ser315" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "266", "end_pos": "266" }, { "start_pos": "368", "end_pos": "368" }, { "start_pos": "715", "end_pos": "715" }, { "start_pos": "931", "end_pos": "931" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "205", "end_pos": "205" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "287", "end_pos": "287" } ] }, { "type": "snv", "site_list": [ { "start_pos": "889", "end_pos": "889" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "266", "end_pos": "266" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "365", "end_pos": "365" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "603", "end_pos": "603" }, { "start_pos": "677", "end_pos": "677" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9ESN9-1.365.365", "start_pos": 365, "end_pos": 365, "uniprot_canonical_ac": "Q9ESN9-1", "length": 1337, "uniprot_id": "JIP3_MOUSE", "protein_name": "C-Jun-amino-terminal kinase-interacting protein 3", "refseq_ac": "NP_001156919", "refseq_name": "C-Jun-amino-terminal kinase-interacting protein 3 isoform b", "gene_name": "Mapk8ip3", "gene_names_uniprotkb": "Mapk8ip3; Jip3; Jsap1; Syd2", "gene_names_refseq": "D17Wsu15e; JIP-3; JSAP1a; JSAP1b; JSAP1c; JSAP1d; JSAP1; Jip3; Mapk8ip3; Syd2; mKIAA1066", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "IIDSTPELDVCPETRLERTG", "down_seq": "SPTQGIVNKAFGINTDSLYH", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by ROCK1", "evidence": [ { "database": "UniProtKB", "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9" } ], "site_lbl": "Ser365" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "266", "end_pos": "266" }, { "start_pos": "368", "end_pos": "368" }, { "start_pos": "715", "end_pos": "715" }, { "start_pos": "931", "end_pos": "931" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "205", "end_pos": "205" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "287", "end_pos": "287" } ] }, { "type": "snv", "site_list": [ { "start_pos": "889", "end_pos": "889" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "266", "end_pos": "266" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "365", "end_pos": "365" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "603", "end_pos": "603" }, { "start_pos": "677", "end_pos": "677" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "Q9ESN9-1.366.366", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q9ESN9-1.368.368", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9ESN9-1.366.366", "start_pos": 366, "end_pos": 366, "uniprot_canonical_ac": "Q9ESN9-1", "length": 1337, "uniprot_id": "JIP3_MOUSE", "protein_name": "C-Jun-amino-terminal kinase-interacting protein 3", "refseq_ac": "NP_001156919", "refseq_name": "C-Jun-amino-terminal kinase-interacting protein 3 isoform b", "gene_name": "Mapk8ip3", "gene_names_uniprotkb": "Mapk8ip3; Jip3; Jsap1; Syd2", "gene_names_refseq": "D17Wsu15e; JIP-3; JSAP1a; JSAP1b; JSAP1c; JSAP1d; JSAP1; Jip3; Mapk8ip3; Syd2; mKIAA1066", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9" }, { "database": "iPTMnet", "id": "Q9ESN9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ESN9" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9ESN9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ESN9", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "IDSTPELDVCPETRLERTGS", "down_seq": "PTQGIVNKAFGINTDSLYHE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q9ESN9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ESN9" } ], "site_lbl": "Ser366" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "266", "end_pos": "266" }, { "start_pos": "368", "end_pos": "368" }, { "start_pos": "715", "end_pos": "715" }, { "start_pos": "931", "end_pos": "931" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "205", "end_pos": "205" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "287", "end_pos": "287" } ] }, { "type": "snv", "site_list": [ { "start_pos": "889", "end_pos": "889" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "266", "end_pos": "266" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "365", "end_pos": "365" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "603", "end_pos": "603" }, { "start_pos": "677", "end_pos": "677" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "Q9ESN9-1.365.365", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q9ESN9-1.368.368", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9ESN9-1.603.603", "start_pos": 603, "end_pos": 603, "uniprot_canonical_ac": "Q9ESN9-1", "length": 1337, "uniprot_id": "JIP3_MOUSE", "protein_name": "C-Jun-amino-terminal kinase-interacting protein 3", "refseq_ac": "NP_001156919", "refseq_name": "C-Jun-amino-terminal kinase-interacting protein 3 isoform b", "gene_name": "Mapk8ip3", "gene_names_uniprotkb": "Mapk8ip3; Jip3; Jsap1; Syd2", "gene_names_refseq": "D17Wsu15e; JIP-3; JSAP1a; JSAP1b; JSAP1c; JSAP1d; JSAP1; Jip3; Mapk8ip3; Syd2; mKIAA1066", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9" }, { "database": "iPTMnet", "id": "Q9ESN9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ESN9" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9ESN9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ESN9", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SSSSPPPAKRSYPSVNIHYK", "down_seq": "PTAAGFSQRRSHALCQISAG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q9ESN9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ESN9" } ], "site_lbl": "Ser603" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "266", "end_pos": "266" }, { "start_pos": "368", "end_pos": "368" }, { "start_pos": "715", "end_pos": "715" }, { "start_pos": "931", "end_pos": "931" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "205", "end_pos": "205" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "287", "end_pos": "287" } ] }, { "type": "snv", "site_list": [ { "start_pos": "889", "end_pos": "889" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "266", "end_pos": "266" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "365", "end_pos": "365" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "603", "end_pos": "603" }, { "start_pos": "677", "end_pos": "677" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9ESN9-1.677.677", "start_pos": 677, "end_pos": 677, "uniprot_canonical_ac": "Q9ESN9-1", "length": 1337, "uniprot_id": "JIP3_MOUSE", "protein_name": "C-Jun-amino-terminal kinase-interacting protein 3", "refseq_ac": "NP_001156919", "refseq_name": "C-Jun-amino-terminal kinase-interacting protein 3 isoform b", "gene_name": "Mapk8ip3", "gene_names_uniprotkb": "Mapk8ip3; Jip3; Jsap1; Syd2", "gene_names_refseq": "D17Wsu15e; JIP-3; JSAP1a; JSAP1b; JSAP1c; JSAP1d; JSAP1; Jip3; Mapk8ip3; Syd2; mKIAA1066", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Comprehensive identification of phosphorylation sites in postsynaptic density preparations.", "journal": "Molecular & cellular proteomics : MCP", "date": "2006", "authors": "Trinidad JC, Specht CG, Thalhammer A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "UniProtKB", "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9" }, { "database": "iPTMnet", "id": "Q9ESN9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ESN9" } ], "reference": [ { "type": "PubMed", "id": "16452087", "url": "https://glygen.org/publication/PubMed/16452087" } ] } ], "crossref": [ { "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "16452087", "url": "https://glygen.org/publication/PubMed/16452087", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9ESN9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ESN9", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NDDGRLQACGWSLPAKYKQL", "down_seq": "PNGGQEDTRMKNVPVPVYCR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9ESN9", "url": "https://www.uniprot.org/uniprotkb/Q9ESN9" }, { "database": "PubMed", "id": "16452087", "url": "https://glygen.org/publication/PubMed/16452087" }, { "database": "iPTMnet", "id": "Q9ESN9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ESN9" } ], "site_lbl": "Ser677" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "266", "end_pos": "266" }, { "start_pos": "368", "end_pos": "368" }, { "start_pos": "715", "end_pos": "715" }, { "start_pos": "931", "end_pos": "931" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "205", "end_pos": "205" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "287", "end_pos": "287" } ] }, { "type": "snv", "site_list": [ { "start_pos": "889", "end_pos": "889" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "266", "end_pos": "266" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "365", "end_pos": "365" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "603", "end_pos": "603" }, { "start_pos": "677", "end_pos": "677" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CI11-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "Q8CI11-1", "length": 538, "uniprot_id": "GNL3_MOUSE", "protein_name": "Guanine nucleotide-binding protein-like 3", "refseq_ac": "NP_705775", "refseq_name": "guanine nucleotide-binding protein-like 3", "gene_name": "Gnl3", "gene_names_uniprotkb": "Gnl3; Ns", "gene_names_refseq": "Gnl3; Ns", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CI11", "url": "https://www.uniprot.org/uniprotkb/Q8CI11" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "The Small Molecule 2-Azido-2-deoxy-glucose Is a Metabolic Chemical Reporter of O-GlcNAc Modifications in Mammalian Cells, Revealing an Unexpected Promiscuity of O-GlcNAc Transferase.", "journal": "ACS chemical biology", "date": "2017", "authors": "Zaro BW, Batt AR, Chuh KN, Navarro MX, Pratt MR", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CI11", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CI11" } ], "reference": [ { "type": "PubMed", "id": "28135057", "url": "https://glygen.org/publication/PubMed/28135057" } ] }, { "title": "Changes in metabolic chemical reporter structure yield a selective probe of O-GlcNAc modification.", "journal": "Journal of the American Chemical Society", "date": "2014", "authors": "Chuh KN, Zaro BW, Piller F, Piller V, Pratt MR", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CI11", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CI11" } ], "reference": [ { "type": "PubMed", "id": "25153642", "url": "https://glygen.org/publication/PubMed/25153642" } ] }, { "title": "The New Chemical Reporter 6-Alkynyl-6-deoxy-GlcNAc Reveals O-GlcNAc Modification of the Apoptotic Caspases That Can Block the Cleavage/Activation of Caspase-8.", "journal": "Journal of the American Chemical Society", "date": "2017", "authors": "Chuh KN, Batt AR, Zaro BW, Darabedian N, Marotta NP, Brennan CK, Amirhekmat A, Pratt MR", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CI11", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CI11" } ], "reference": [ { "type": "PubMed", "id": "28528544", "url": "https://glygen.org/publication/PubMed/28528544" } ] } ], "crossref": [ { "id": "28135057", "url": "https://glygen.org/publication/PubMed/28135057", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CI11", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CI11", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "25153642", "url": "https://glygen.org/publication/PubMed/25153642", "database": "PubMed", "categories": [ "Other" ] }, { "id": "28528544", "url": "https://glygen.org/publication/PubMed/28528544", "database": "PubMed", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "28135057", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/28135057" }, { "id": "Q8CI11", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CI11" }, { "id": "25153642", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/25153642" }, { "id": "28528544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/28528544" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "256", "end_pos": "256" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "518", "end_pos": "518" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CI11-1.256.256", "start_pos": 256, "end_pos": 256, "uniprot_canonical_ac": "Q8CI11-1", "length": 538, "uniprot_id": "GNL3_MOUSE", "protein_name": "Guanine nucleotide-binding protein-like 3", "refseq_ac": "NP_705775", "refseq_name": "guanine nucleotide-binding protein-like 3", "gene_name": "Gnl3", "gene_names_uniprotkb": "Gnl3; Ns", "gene_names_refseq": "Gnl3; Ns", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CI11", "url": "https://www.uniprot.org/uniprotkb/Q8CI11" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "GNL3L depletion destabilizes MDM2 and induces p53-dependent G2/M arrest.", "journal": "Oncogene", "date": "2011", "authors": "Meng L, Hsu JK, Tsai RY", "evidence": [ { "database": "UniProtKB", "id": "Q8CI11", "url": "https://www.uniprot.org/uniprotkb/Q8CI11" } ], "reference": [ { "type": "PubMed", "id": "21132010", "url": "https://glygen.org/publication/PubMed/21132010" } ] } ], "crossref": [ { "id": "Q8CI11", "url": "https://www.uniprot.org/uniprotkb/Q8CI11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21132010", "url": "https://glygen.org/publication/PubMed/21132010", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "G", "start_aa": "G", "up_seq": "WKLLGDFQQSCGKDIQVGVI", "down_seq": "FPNVGKSSVINSLKQEWICN", "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "V", "comment": "Mislocalized to the nucleoplasm. No effect on MDM2-binding.", "evidence": [ { "database": "UniProtKB", "id": "Q8CI11", "url": "https://www.uniprot.org/uniprotkb/Q8CI11" }, { "database": "PubMed", "id": "21132010", "url": "https://glygen.org/publication/PubMed/21132010" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "256", "end_pos": "256" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "518", "end_pos": "518" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CI11-1.101.101", "start_pos": 101, "end_pos": 101, "uniprot_canonical_ac": "Q8CI11-1", "length": 538, "uniprot_id": "GNL3_MOUSE", "protein_name": "Guanine nucleotide-binding protein-like 3", "refseq_ac": "NP_705775", "refseq_name": "guanine nucleotide-binding protein-like 3", "gene_name": "Gnl3", "gene_names_uniprotkb": "Gnl3; Ns", "gene_names_refseq": "Gnl3; Ns", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CI11", "url": "https://www.uniprot.org/uniprotkb/Q8CI11" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8CI11", "url": "https://www.uniprot.org/uniprotkb/Q8CI11", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DRQKEQERKRKLEVSPGDEQ", "down_seq": "NVETREESDEPKRKKAKAGK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8CI11", "url": "https://www.uniprot.org/uniprotkb/Q8CI11" } ], "site_lbl": "Ser101" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "256", "end_pos": "256" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "518", "end_pos": "518" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "Q8CI11-1.95.95", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8CI11-1.493.493", "start_pos": 493, "end_pos": 493, "uniprot_canonical_ac": "Q8CI11-1", "length": 538, "uniprot_id": "GNL3_MOUSE", "protein_name": "Guanine nucleotide-binding protein-like 3", "refseq_ac": "NP_705775", "refseq_name": "guanine nucleotide-binding protein-like 3", "gene_name": "Gnl3", "gene_names_uniprotkb": "Gnl3; Ns", "gene_names_refseq": "Gnl3; Ns", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CI11", "url": "https://www.uniprot.org/uniprotkb/Q8CI11" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8CI11", "url": "https://www.uniprot.org/uniprotkb/Q8CI11" }, { "database": "iPTMnet", "id": "Q8CI11", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CI11" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q8CI11", "url": "https://www.uniprot.org/uniprotkb/Q8CI11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CI11", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CI11", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EDKQDADDQENGSGERNAEI", "down_seq": "DVAPVEETRELSPEQSTAGK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8CI11", "url": "https://www.uniprot.org/uniprotkb/Q8CI11" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q8CI11", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CI11" } ], "site_lbl": "Ser493" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "256", "end_pos": "256" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "518", "end_pos": "518" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "upstream", "id": "Q8CI11-1.505.505", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CI11-1.505.505", "start_pos": 505, "end_pos": 505, "uniprot_canonical_ac": "Q8CI11-1", "length": 538, "uniprot_id": "GNL3_MOUSE", "protein_name": "Guanine nucleotide-binding protein-like 3", "refseq_ac": "NP_705775", "refseq_name": "guanine nucleotide-binding protein-like 3", "gene_name": "Gnl3", "gene_names_uniprotkb": "Gnl3; Ns", "gene_names_refseq": "Gnl3; Ns", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CI11", "url": "https://www.uniprot.org/uniprotkb/Q8CI11" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8CI11", "url": "https://www.uniprot.org/uniprotkb/Q8CI11" }, { "database": "iPTMnet", "id": "Q8CI11", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CI11" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "title": "The phagosomal proteome in interferon-gamma-activated macrophages.", "journal": "Immunity", "date": "2009", "authors": "Trost M, English L, Lemieux S, Courcelles M, Desjardins M, Thibault P", "evidence": [ { "database": "UniProtKB", "id": "Q8CI11", "url": "https://www.uniprot.org/uniprotkb/Q8CI11" }, { "database": "iPTMnet", "id": "Q8CI11", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CI11" } ], "reference": [ { "type": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" } ] } ], "crossref": [ { "id": "Q8CI11", "url": "https://www.uniprot.org/uniprotkb/Q8CI11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CI11", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CI11", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SGERNAEISDVAPVEETREL", "down_seq": "PEQSTAGKPSDGSSALDRAS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8CI11", "url": "https://www.uniprot.org/uniprotkb/Q8CI11" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" }, { "database": "iPTMnet", "id": "Q8CI11", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CI11" } ], "site_lbl": "Ser505" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "256", "end_pos": "256" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "518", "end_pos": "518" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "Q8CI11-1.493.493", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q8CI11-1.518.518", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CI11-1.518.518", "start_pos": 518, "end_pos": 518, "uniprot_canonical_ac": "Q8CI11-1", "length": 538, "uniprot_id": "GNL3_MOUSE", "protein_name": "Guanine nucleotide-binding protein-like 3", "refseq_ac": "NP_705775", "refseq_name": "guanine nucleotide-binding protein-like 3", "gene_name": "Gnl3", "gene_names_uniprotkb": "Gnl3; Ns", "gene_names_refseq": "Gnl3; Ns", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CI11", "url": "https://www.uniprot.org/uniprotkb/Q8CI11" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8CI11", "url": "https://www.uniprot.org/uniprotkb/Q8CI11", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VEETRELSPEQSTAGKPSDG", "down_seq": "SALDRASQEDETYDFTTDYI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8CI11", "url": "https://www.uniprot.org/uniprotkb/Q8CI11" } ], "site_lbl": "Ser518" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "256", "end_pos": "256" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "518", "end_pos": "518" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "Q8CI11-1.505.505", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8CI11-1.95.95", "start_pos": 95, "end_pos": 95, "uniprot_canonical_ac": "Q8CI11-1", "length": 538, "uniprot_id": "GNL3_MOUSE", "protein_name": "Guanine nucleotide-binding protein-like 3", "refseq_ac": "NP_705775", "refseq_name": "guanine nucleotide-binding protein-like 3", "gene_name": "Gnl3", "gene_names_uniprotkb": "Gnl3; Ns", "gene_names_refseq": "Gnl3; Ns", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CI11", "url": "https://www.uniprot.org/uniprotkb/Q8CI11" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8CI11", "url": "https://www.uniprot.org/uniprotkb/Q8CI11" }, { "database": "iPTMnet", "id": "Q8CI11", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CI11" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q8CI11", "url": "https://www.uniprot.org/uniprotkb/Q8CI11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CI11", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CI11", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KQQQKLDRQKEQERKRKLEV", "down_seq": "PGDEQSNVETREESDEPKRK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8CI11", "url": "https://www.uniprot.org/uniprotkb/Q8CI11" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q8CI11", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CI11" } ], "site_lbl": "Ser95" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "256", "end_pos": "256" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "518", "end_pos": "518" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "upstream", "id": "Q8CI11-1.101.101", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19001-1.54.54", "start_pos": 54, "end_pos": 54, "uniprot_canonical_ac": "P19001-1", "length": 403, "uniprot_id": "K1C19_MOUSE", "protein_name": "Keratin, type I cytoskeletal 19", "refseq_ac": "NP_032497", "refseq_name": "keratin, type I cytoskeletal 19 isoform 1", "gene_name": "Krt19", "gene_names_uniprotkb": "Krt19; Krt1-19", "gene_names_refseq": "CK-19; EndoC; K19; Krt-1.19; Krt1-19; Krt19", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P19001", "url": "https://www.uniprot.org/uniprotkb/P19001" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Cytosolic N-GlcNAc proteins are formed by the action of endo-beta-N-acetylglucosaminidase.", "journal": "Biochemical and biophysical research communications", "date": "2020", "authors": "Maynard JC, Fujihira H, Dolgonos GE, Suzuki T, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "P19001", "url": "https://oglcnac.org/atlas/detail/P19001" } ], "reference": [ { "type": "PubMed", "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141" } ] } ], "crossref": [ { "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P19001", "url": "https://oglcnac.org/atlas/detail/P19001", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "PSIHGGSGGRGVSVSSTRFV", "down_seq": "SSSGSYGGVRGGSFSGTLAV", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr54", "evidence": [ { "id": "32782141", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32782141" }, { "id": "P19001", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P19001" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "54", "end_pos": "54" }, { "start_pos": "55", "end_pos": "55" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "14", "end_pos": "14" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "394", "end_pos": "394" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "75", "end_pos": "75" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P19001-1.35.35", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P19001-1.40.40", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P19001-1.55.55", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P19001-1.57.57", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P19001-1.67.67", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19001-1.55.55", "start_pos": 55, "end_pos": 55, "uniprot_canonical_ac": "P19001-1", "length": 403, "uniprot_id": "K1C19_MOUSE", "protein_name": "Keratin, type I cytoskeletal 19", "refseq_ac": "NP_032497", "refseq_name": "keratin, type I cytoskeletal 19 isoform 1", "gene_name": "Krt19", "gene_names_uniprotkb": "Krt19; Krt1-19", "gene_names_refseq": "CK-19; EndoC; K19; Krt-1.19; Krt1-19; Krt19", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P19001", "url": "https://www.uniprot.org/uniprotkb/P19001" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Cytosolic N-GlcNAc proteins are formed by the action of endo-beta-N-acetylglucosaminidase.", "journal": "Biochemical and biophysical research communications", "date": "2020", "authors": "Maynard JC, Fujihira H, Dolgonos GE, Suzuki T, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "P19001", "url": "https://oglcnac.org/atlas/detail/P19001" } ], "reference": [ { "type": "PubMed", "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141" } ] } ], "crossref": [ { "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P19001", "url": "https://oglcnac.org/atlas/detail/P19001", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SIHGGSGGRGVSVSSTRFVT", "down_seq": "SSGSYGGVRGGSFSGTLAVS", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser55", "evidence": [ { "id": "32782141", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32782141" }, { "id": "P19001", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P19001" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "54", "end_pos": "54" }, { "start_pos": "55", "end_pos": "55" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "14", "end_pos": "14" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "394", "end_pos": "394" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "75", "end_pos": "75" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P19001-1.35.35", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P19001-1.40.40", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P19001-1.54.54", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P19001-1.57.57", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P19001-1.67.67", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P19001-1.75.75", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19001-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "P19001-1", "length": 403, "uniprot_id": "K1C19_MOUSE", "protein_name": "Keratin, type I cytoskeletal 19", "refseq_ac": "NP_032497", "refseq_name": "keratin, type I cytoskeletal 19 isoform 1", "gene_name": "Krt19", "gene_names_uniprotkb": "Krt19; Krt1-19", "gene_names_refseq": "CK-19; EndoC; K19; Krt-1.19; Krt1-19; Krt19", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P19001", "url": "https://www.uniprot.org/uniprotkb/P19001" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Epigenetic co-regulator HCF-1 promotes lung cancer via O-GlcNAcylation-dependent pathways.", "journal": "Molecular therapy. Oncology", "date": "2025-12-18", "authors": "Srivastava Priyanka P, Dasari Abhilash, Kumar Saran, Gupta Ishaan, Jain Deepali, Minocha Shilpi", "evidence": [ { "database": "O-GlcNAc Database", "id": "P19001", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P19001" } ], "reference": [ { "type": "PubMed", "id": "41018975", "url": "https://glygen.org/publication/PubMed/41018975" } ] }, { "title": "Dynamic eIF3a O-GlcNAcylation controls translation reinitiation during nutrient stress.", "journal": "Nature chemical biology", "date": "2022", "authors": "Shu XE, Mao Y, Jia L, Qian SB", "evidence": [ { "database": "O-GlcNAc Database", "id": "P19001", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P19001" } ], "reference": [ { "type": "PubMed", "id": "34887587", "url": "https://glygen.org/publication/PubMed/34887587" } ] } ], "crossref": [ { "id": "41018975", "url": "https://glygen.org/publication/PubMed/41018975", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P19001", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P19001", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "34887587", "url": "https://glygen.org/publication/PubMed/34887587", "database": "PubMed", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "41018975", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/41018975" }, { "id": "P19001", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P19001" }, { "id": "34887587", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34887587" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "54", "end_pos": "54" }, { "start_pos": "55", "end_pos": "55" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "14", "end_pos": "14" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "394", "end_pos": "394" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "75", "end_pos": "75" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "upstream", "id": "P19001-1.14.14", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19001-1.14.14", "start_pos": 14, "end_pos": 14, "uniprot_canonical_ac": "P19001-1", "length": 403, "uniprot_id": "K1C19_MOUSE", "protein_name": "Keratin, type I cytoskeletal 19", "refseq_ac": "NP_032497", "refseq_name": "keratin, type I cytoskeletal 19 isoform 1", "gene_name": "Krt19", "gene_names_uniprotkb": "Krt19; Krt1-19", "gene_names_refseq": "CK-19; EndoC; K19; Krt-1.19; Krt1-19; Krt19", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P19001", "url": "https://www.uniprot.org/uniprotkb/P19001" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P19001", "url": "https://www.uniprot.org/uniprotkb/P19001", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MTSYSYRQTSAMS", "down_seq": "FGGTGGGSVRIGSGGVFRAP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P19001", "url": "https://www.uniprot.org/uniprotkb/P19001" } ], "site_lbl": "Ser14" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "54", "end_pos": "54" }, { "start_pos": "55", "end_pos": "55" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "14", "end_pos": "14" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "394", "end_pos": "394" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "75", "end_pos": "75" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "P19001-1.0.0", "categories": [ "glycosylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P19001-1.22.22", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P19001-1.27.27", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P19001-1.22.22", "start_pos": 22, "end_pos": 22, "uniprot_canonical_ac": "P19001-1", "length": 403, "uniprot_id": "K1C19_MOUSE", "protein_name": "Keratin, type I cytoskeletal 19", "refseq_ac": "NP_032497", "refseq_name": "keratin, type I cytoskeletal 19 isoform 1", "gene_name": "Krt19", "gene_names_uniprotkb": "Krt19; Krt1-19", "gene_names_refseq": "CK-19; EndoC; K19; Krt-1.19; Krt1-19; Krt19", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P19001", "url": "https://www.uniprot.org/uniprotkb/P19001" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P19001", "url": "https://www.uniprot.org/uniprotkb/P19001", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TSYSYRQTSAMSSFGGTGGG", "down_seq": "VRIGSGGVFRAPSIHGGSGG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P19001", "url": "https://www.uniprot.org/uniprotkb/P19001" } ], "site_lbl": "Ser22" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "54", "end_pos": "54" }, { "start_pos": "55", "end_pos": "55" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "14", "end_pos": "14" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "394", "end_pos": "394" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "75", "end_pos": "75" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "P19001-1.14.14", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P19001-1.27.27", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P19001-1.35.35", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P19001-1.40.40", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P19001-1.27.27", "start_pos": 27, "end_pos": 27, "uniprot_canonical_ac": "P19001-1", "length": 403, "uniprot_id": "K1C19_MOUSE", "protein_name": "Keratin, type I cytoskeletal 19", "refseq_ac": "NP_032497", "refseq_name": "keratin, type I cytoskeletal 19 isoform 1", "gene_name": "Krt19", "gene_names_uniprotkb": "Krt19; Krt1-19", "gene_names_refseq": "CK-19; EndoC; K19; Krt-1.19; Krt1-19; Krt19", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P19001", "url": "https://www.uniprot.org/uniprotkb/P19001" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P19001", "url": "https://www.uniprot.org/uniprotkb/P19001", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RQTSAMSSFGGTGGGSVRIG", "down_seq": "GGVFRAPSIHGGSGGRGVSV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P19001", "url": "https://www.uniprot.org/uniprotkb/P19001" } ], "site_lbl": "Ser27" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "54", "end_pos": "54" }, { "start_pos": "55", "end_pos": "55" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "14", "end_pos": "14" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "394", "end_pos": "394" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "75", "end_pos": "75" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P19001-1.14.14", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P19001-1.22.22", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P19001-1.35.35", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P19001-1.40.40", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P19001-1.326.326", "start_pos": 326, "end_pos": 326, "uniprot_canonical_ac": "P19001-1", "length": 403, "uniprot_id": "K1C19_MOUSE", "protein_name": "Keratin, type I cytoskeletal 19", "refseq_ac": "NP_032497", "refseq_name": "keratin, type I cytoskeletal 19 isoform 1", "gene_name": "Krt19", "gene_names_uniprotkb": "Krt19; Krt1-19", "gene_names_refseq": "CK-19; EndoC; K19; Krt-1.19; Krt1-19; Krt19", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P19001", "url": "https://www.uniprot.org/uniprotkb/P19001" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P19001", "url": "https://www.uniprot.org/uniprotkb/P19001", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "LQGLEIELQSQLSMKAALEG", "down_seq": "LAETEARYGVQLSQIQSVIS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P19001", "url": "https://www.uniprot.org/uniprotkb/P19001" } ], "site_lbl": "Thr326" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "54", "end_pos": "54" }, { "start_pos": "55", "end_pos": "55" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "14", "end_pos": "14" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "394", "end_pos": "394" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "75", "end_pos": "75" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P19001-1.35.35", "start_pos": 35, "end_pos": 35, "uniprot_canonical_ac": "P19001-1", "length": 403, "uniprot_id": "K1C19_MOUSE", "protein_name": "Keratin, type I cytoskeletal 19", "refseq_ac": "NP_032497", "refseq_name": "keratin, type I cytoskeletal 19 isoform 1", "gene_name": "Krt19", "gene_names_uniprotkb": "Krt19; Krt1-19", "gene_names_refseq": "CK-19; EndoC; K19; Krt-1.19; Krt1-19; Krt19", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P19001", "url": "https://www.uniprot.org/uniprotkb/P19001" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P19001", "url": "https://www.uniprot.org/uniprotkb/P19001", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "FGGTGGGSVRIGSGGVFRAP", "down_seq": "IHGGSGGRGVSVSSTRFVTS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P19001", "url": "https://www.uniprot.org/uniprotkb/P19001" } ], "site_lbl": "Ser35" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "54", "end_pos": "54" }, { "start_pos": "55", "end_pos": "55" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "14", "end_pos": "14" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "394", "end_pos": "394" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "75", "end_pos": "75" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P19001-1.22.22", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P19001-1.27.27", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P19001-1.40.40", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P19001-1.54.54", "categories": [ "glycosylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P19001-1.55.55", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P19001-1.394.394", "start_pos": 394, "end_pos": 394, "uniprot_canonical_ac": "P19001-1", "length": 403, "uniprot_id": "K1C19_MOUSE", "protein_name": "Keratin, type I cytoskeletal 19", "refseq_ac": "NP_032497", "refseq_name": "keratin, type I cytoskeletal 19 isoform 1", "gene_name": "Krt19", "gene_names_uniprotkb": "Krt19; Krt1-19", "gene_names_refseq": "CK-19; EndoC; K19; Krt-1.19; Krt1-19; Krt19", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P19001", "url": "https://www.uniprot.org/uniprotkb/P19001" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Characterization of in vivo keratin 19 phosphorylation on tyrosine-391.", "journal": "PloS one", "date": "2010", "authors": "Zhou Q, Snider NT, Liao J, Li DH, Hong A, Ku NO, Cartwright CA, Omary MB", "evidence": [ { "database": "UniProtKB", "id": "P19001", "url": "https://www.uniprot.org/uniprotkb/P19001" }, { "database": "iPTMnet", "id": "P19001", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19001" } ], "reference": [ { "type": "PubMed", "id": "21049038", "url": "https://glygen.org/publication/PubMed/21049038" } ] } ], "crossref": [ { "id": "P19001", "url": "https://www.uniprot.org/uniprotkb/P19001", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21049038", "url": "https://glygen.org/publication/PubMed/21049038", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P19001", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19001", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "SRLEQEIATYRSLLEGQEAH", "down_seq": "NNLPTPKAI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "P19001", "url": "https://www.uniprot.org/uniprotkb/P19001" }, { "database": "PubMed", "id": "21049038", "url": "https://glygen.org/publication/PubMed/21049038" }, { "database": "iPTMnet", "id": "P19001", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19001" } ], "site_lbl": "Tyr394" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "54", "end_pos": "54" }, { "start_pos": "55", "end_pos": "55" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "14", "end_pos": "14" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "394", "end_pos": "394" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "75", "end_pos": "75" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19001-1.40.40", "start_pos": 40, "end_pos": 40, "uniprot_canonical_ac": "P19001-1", "length": 403, "uniprot_id": "K1C19_MOUSE", "protein_name": "Keratin, type I cytoskeletal 19", "refseq_ac": "NP_032497", "refseq_name": "keratin, type I cytoskeletal 19 isoform 1", "gene_name": "Krt19", "gene_names_uniprotkb": "Krt19; Krt1-19", "gene_names_refseq": "CK-19; EndoC; K19; Krt-1.19; Krt1-19; Krt19", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P19001", "url": "https://www.uniprot.org/uniprotkb/P19001" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P19001", "url": "https://www.uniprot.org/uniprotkb/P19001", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GGSVRIGSGGVFRAPSIHGG", "down_seq": "GGRGVSVSSTRFVTSSSGSY", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P19001", "url": "https://www.uniprot.org/uniprotkb/P19001" } ], "site_lbl": "Ser40" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "54", "end_pos": "54" }, { "start_pos": "55", "end_pos": "55" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "14", "end_pos": "14" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "394", "end_pos": "394" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "75", "end_pos": "75" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P19001-1.22.22", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P19001-1.27.27", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P19001-1.35.35", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P19001-1.54.54", "categories": [ "glycosylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P19001-1.55.55", "categories": [ "glycosylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P19001-1.57.57", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P19001-1.57.57", "start_pos": 57, "end_pos": 57, "uniprot_canonical_ac": "P19001-1", "length": 403, "uniprot_id": "K1C19_MOUSE", "protein_name": "Keratin, type I cytoskeletal 19", "refseq_ac": "NP_032497", "refseq_name": "keratin, type I cytoskeletal 19 isoform 1", "gene_name": "Krt19", "gene_names_uniprotkb": "Krt19; Krt1-19", "gene_names_refseq": "CK-19; EndoC; K19; Krt-1.19; Krt1-19; Krt19", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P19001", "url": "https://www.uniprot.org/uniprotkb/P19001" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P19001", "url": "https://www.uniprot.org/uniprotkb/P19001", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "HGGSGGRGVSVSSTRFVTSS", "down_seq": "GSYGGVRGGSFSGTLAVSDG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P19001", "url": "https://www.uniprot.org/uniprotkb/P19001" } ], "site_lbl": "Ser57" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "54", "end_pos": "54" }, { "start_pos": "55", "end_pos": "55" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "14", "end_pos": "14" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "394", "end_pos": "394" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "75", "end_pos": "75" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P19001-1.40.40", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P19001-1.54.54", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P19001-1.55.55", "categories": [ "glycosylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P19001-1.67.67", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P19001-1.75.75", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P19001-1.67.67", "start_pos": 67, "end_pos": 67, "uniprot_canonical_ac": "P19001-1", "length": 403, "uniprot_id": "K1C19_MOUSE", "protein_name": "Keratin, type I cytoskeletal 19", "refseq_ac": "NP_032497", "refseq_name": "keratin, type I cytoskeletal 19 isoform 1", "gene_name": "Krt19", "gene_names_uniprotkb": "Krt19; Krt1-19", "gene_names_refseq": "CK-19; EndoC; K19; Krt-1.19; Krt1-19; Krt19", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P19001", "url": "https://www.uniprot.org/uniprotkb/P19001" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P19001", "url": "https://www.uniprot.org/uniprotkb/P19001" }, { "database": "iPTMnet", "id": "P19001", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19001" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "P19001", "url": "https://www.uniprot.org/uniprotkb/P19001", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P19001", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19001", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VSSTRFVTSSSGSYGGVRGG", "down_seq": "FSGTLAVSDGLLSGNEKITM", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P19001", "url": "https://www.uniprot.org/uniprotkb/P19001" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "P19001", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19001" } ], "site_lbl": "Ser67" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "54", "end_pos": "54" }, { "start_pos": "55", "end_pos": "55" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "14", "end_pos": "14" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "394", "end_pos": "394" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "75", "end_pos": "75" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P19001-1.54.54", "categories": [ "glycosylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P19001-1.55.55", "categories": [ "glycosylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P19001-1.57.57", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P19001-1.75.75", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19001-1.75.75", "start_pos": 75, "end_pos": 75, "uniprot_canonical_ac": "P19001-1", "length": 403, "uniprot_id": "K1C19_MOUSE", "protein_name": "Keratin, type I cytoskeletal 19", "refseq_ac": "NP_032497", "refseq_name": "keratin, type I cytoskeletal 19 isoform 1", "gene_name": "Krt19", "gene_names_uniprotkb": "Krt19; Krt1-19", "gene_names_refseq": "CK-19; EndoC; K19; Krt-1.19; Krt1-19; Krt19", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P19001", "url": "https://www.uniprot.org/uniprotkb/P19001" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P19001", "url": "https://www.uniprot.org/uniprotkb/P19001" }, { "database": "iPTMnet", "id": "P19001", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19001" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "P19001", "url": "https://www.uniprot.org/uniprotkb/P19001", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P19001", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19001", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SSSGSYGGVRGGSFSGTLAV", "down_seq": "DGLLSGNEKITMQNLNDRLA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P19001", "url": "https://www.uniprot.org/uniprotkb/P19001" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "P19001", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19001" } ], "site_lbl": "Ser75" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "54", "end_pos": "54" }, { "start_pos": "55", "end_pos": "55" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "14", "end_pos": "14" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "394", "end_pos": "394" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "75", "end_pos": "75" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P19001-1.55.55", "categories": [ "glycosylation_flag" ] }, { "distance": 18, "direction": "downstream", "id": "P19001-1.57.57", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P19001-1.67.67", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P63141-1.207.207", "start_pos": 207, "end_pos": 207, "uniprot_canonical_ac": "P63141-1", "length": 499, "uniprot_id": "KCNA2_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily A member 2", "refseq_ac": "NP_032443", "refseq_name": "potassium voltage-gated channel subfamily A member 2", "gene_name": "Kcna2", "gene_names_uniprotkb": "Kcna2", "gene_names_refseq": "Akr6a4; Gm10672; Kca1-2; Kcna2; Kv1.2; Mk-2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P63141", "url": "https://www.uniprot.org/uniprotkb/P63141" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P63141", "url": "https://www.uniprot.org/uniprotkb/P63141", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "IFRDENEDMHGGGVTFHTYS", "down_seq": "STIGYQQSTSFTDPFFIVET", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn207", "evidence": [ { "id": "P63141", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P63141#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "207", "end_pos": "207" }, { "start_pos": "38", "end_pos": "38" }, { "start_pos": "441", "end_pos": "441" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "483", "end_pos": "483" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "402", "end_pos": "402" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "429", "end_pos": "429" }, { "start_pos": "434", "end_pos": "434" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "441", "end_pos": "441" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "468", "end_pos": "468" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P63141-1.38.38", "start_pos": 38, "end_pos": 38, "uniprot_canonical_ac": "P63141-1", "length": 499, "uniprot_id": "KCNA2_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily A member 2", "refseq_ac": "NP_032443", "refseq_name": "potassium voltage-gated channel subfamily A member 2", "gene_name": "Kcna2", "gene_names_uniprotkb": "Kcna2", "gene_names_refseq": "Akr6a4; Gm10672; Kca1-2; Kcna2; Kv1.2; Mk-2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P63141", "url": "https://www.uniprot.org/uniprotkb/P63141" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "HPQDTYDPEADHECCERVVI", "down_seq": "ISGLRFETQLKTLAQFPETL", "glycosylation": [ { "glytoucan_ac": "G02815KT", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "VVINISGLR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn38", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "207", "end_pos": "207" }, { "start_pos": "38", "end_pos": "38" }, { "start_pos": "441", "end_pos": "441" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "483", "end_pos": "483" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "402", "end_pos": "402" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "429", "end_pos": "429" }, { "start_pos": "434", "end_pos": "434" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "441", "end_pos": "441" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "468", "end_pos": "468" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P63141-1.441.441", "start_pos": 441, "end_pos": 441, "uniprot_canonical_ac": "P63141-1", "length": 499, "uniprot_id": "KCNA2_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily A member 2", "refseq_ac": "NP_032443", "refseq_name": "potassium voltage-gated channel subfamily A member 2", "gene_name": "Kcna2", "gene_names_uniprotkb": "Kcna2", "gene_names_refseq": "Akr6a4; Gm10672; Kca1-2; Kcna2; Kv1.2; Mk-2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P63141", "url": "https://www.uniprot.org/uniprotkb/P63141" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Quantitative Profiling of Protein O-GlcNAcylation Sites by an Isotope-Tagged Cleavable Linker.", "journal": "ACS chemical biology", "date": "2018", "authors": "Qin K, Zhu Y, Qin W, Gao J, Shao X, Wang YL, Zhou W, Wang C, Chen X", "evidence": [ { "database": "O-GlcNAc Database", "id": "P63141", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P63141" }, { "database": "O-GlcNAc Atlas", "id": "P63141", "url": "https://oglcnac.org/atlas/detail/P63141" } ], "reference": [ { "type": "PubMed", "id": "30059200", "url": "https://glygen.org/publication/PubMed/30059200" } ] }, { "title": "Characterization and chemoproteomic profiling of protein O-GlcNAcylation in SOD1-G93A mouse model.", "journal": "Molecular medicine (Cambridge, Mass.)", "date": "2025-02-28", "authors": "Hao Yi, Li Zhongzhong, Du Xinyan, Xie Qingsong, Li Dongxiao, Lei Shaoyuan, Guo Yansu", "evidence": [ { "database": "O-GlcNAc Database", "id": "P63141", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P63141" } ], "reference": [ { "type": "PubMed", "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "P63141", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P63141" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "P63141", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P63141" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] }, { "title": "Trafficking-dependent phosphorylation of Kv1.2 regulates voltage-gated potassium channel cell surface expression.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Yang JW, Vacher H, Park KS, Clark E, Trimmer JS", "evidence": [ { "database": "iPTMnet", "id": "P63141-1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63141-1" } ], "reference": [ { "type": "PubMed", "id": "18056633", "url": "https://glygen.org/publication/PubMed/18056633" } ] }, { "title": "Identification of a molecular locus for normalizing dysregulated GABA release from interneurons in the Fragile X brain.", "journal": "Molecular psychiatry", "date": "2020-09", "authors": "Yang Yi-Mei, Arsenault Jason, Bah Alaji, Krzeminski Mickael, Fekete Adam, Chao Owen Y, Pacey Laura K, Wang Alex, Forman-Kay Julie, Hampson David R, Wang Lu-Yang", "evidence": [ { "database": "iPTMnet", "id": "P63141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63141" } ], "reference": [ { "type": "PubMed", "id": "30224722", "url": "https://glygen.org/publication/PubMed/30224722" } ] } ], "crossref": [ { "id": "30059200", "url": "https://glygen.org/publication/PubMed/30059200", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P63141", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P63141", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P63141", "url": "https://oglcnac.org/atlas/detail/P63141", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "P63141", "url": "https://www.uniprot.org/uniprotkb/P63141", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P63141", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P63141", "database": "PRO", "categories": [ "Other" ] }, { "id": "P63141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63141", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18056633", "url": "https://glygen.org/publication/PubMed/18056633", "database": "PubMed", "categories": [ "Other" ] }, { "id": "30224722", "url": "https://glygen.org/publication/PubMed/30224722", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TEGEEQAQYLQVTSCPKIPS", "down_seq": "PDLKKSRSASTISKSDYMEI", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser441", "evidence": [ { "id": "30059200", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30059200" }, { "id": "P63141", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P63141" }, { "id": "40021952", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40021952" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" }, { "id": "P63141", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P63141" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P63141", "url": "https://www.uniprot.org/uniprotkb/P63141" }, { "database": "PRO", "id": "P63141", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P63141" }, { "database": "iPTMnet", "id": "P63141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63141" }, { "database": "PubMed", "id": "18056633", "url": "https://glygen.org/publication/PubMed/18056633" }, { "database": "PubMed", "id": "30224722", "url": "https://glygen.org/publication/PubMed/30224722" } ], "site_lbl": "Ser441" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "207", "end_pos": "207" }, { "start_pos": "38", "end_pos": "38" }, { "start_pos": "441", "end_pos": "441" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "483", "end_pos": "483" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "402", "end_pos": "402" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "429", "end_pos": "429" }, { "start_pos": "434", "end_pos": "434" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "441", "end_pos": "441" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "468", "end_pos": "468" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "P63141-1.429.429", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P63141-1.434.434", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P63141-1.440.440", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P63141-1.449.449", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P63141-1.458.458", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P63141-1.479.479", "start_pos": 479, "end_pos": 479, "uniprot_canonical_ac": "P63141-1", "length": 499, "uniprot_id": "KCNA2_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily A member 2", "refseq_ac": "NP_032443", "refseq_name": "potassium voltage-gated channel subfamily A member 2", "gene_name": "Kcna2", "gene_names_uniprotkb": "Kcna2", "gene_names_refseq": "Akr6a4; Gm10672; Kca1-2; Kcna2; Kv1.2; Mk-2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P63141", "url": "https://www.uniprot.org/uniprotkb/P63141" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Quantitative Profiling of Protein O-GlcNAcylation Sites by an Isotope-Tagged Cleavable Linker.", "journal": "ACS chemical biology", "date": "2018", "authors": "Qin K, Zhu Y, Qin W, Gao J, Shao X, Wang YL, Zhou W, Wang C, Chen X", "evidence": [ { "database": "O-GlcNAc Database", "id": "P63141", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P63141" }, { "database": "O-GlcNAc Atlas", "id": "P63141", "url": "https://oglcnac.org/atlas/detail/P63141" } ], "reference": [ { "type": "PubMed", "id": "30059200", "url": "https://glygen.org/publication/PubMed/30059200" } ] }, { "title": "Characterization and chemoproteomic profiling of protein O-GlcNAcylation in SOD1-G93A mouse model.", "journal": "Molecular medicine (Cambridge, Mass.)", "date": "2025-02-28", "authors": "Hao Yi, Li Zhongzhong, Du Xinyan, Xie Qingsong, Li Dongxiao, Lei Shaoyuan, Guo Yansu", "evidence": [ { "database": "O-GlcNAc Database", "id": "P63141", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P63141" } ], "reference": [ { "type": "PubMed", "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "P63141", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P63141" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "P63141", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P63141" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] } ], "crossref": [ { "id": "30059200", "url": "https://glygen.org/publication/PubMed/30059200", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P63141", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P63141", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "MEIQEGVNNSNEDFREENLK", "down_seq": "ANCTLANTNYVNITKMLTDV", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr479", "evidence": [ { "id": "30059200", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30059200" }, { "id": "P63141", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P63141" }, { "id": "40021952", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40021952" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "207", "end_pos": "207" }, { "start_pos": "38", "end_pos": "38" }, { "start_pos": "441", "end_pos": "441" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "483", "end_pos": "483" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "402", "end_pos": "402" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "429", "end_pos": "429" }, { "start_pos": "434", "end_pos": "434" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "441", "end_pos": "441" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "468", "end_pos": "468" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "P63141-1.468.468", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P63141-1.481.481", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P63141-1.483.483", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P63141-1.481.481", "start_pos": 481, "end_pos": 481, "uniprot_canonical_ac": "P63141-1", "length": 499, "uniprot_id": "KCNA2_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily A member 2", "refseq_ac": "NP_032443", "refseq_name": "potassium voltage-gated channel subfamily A member 2", "gene_name": "Kcna2", "gene_names_uniprotkb": "Kcna2", "gene_names_refseq": "Akr6a4; Gm10672; Kca1-2; Kcna2; Kv1.2; Mk-2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P63141", "url": "https://www.uniprot.org/uniprotkb/P63141" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "IQEGVNNSNEDFREENLKTA", "down_seq": "CTLANTNYVNITKMLTDV", "glycosylation": [ { "glytoucan_ac": "G72747WU", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "TANCTLANTNYVNITK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn481", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "207", "end_pos": "207" }, { "start_pos": "38", "end_pos": "38" }, { "start_pos": "441", "end_pos": "441" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "483", "end_pos": "483" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "402", "end_pos": "402" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "429", "end_pos": "429" }, { "start_pos": "434", "end_pos": "434" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "441", "end_pos": "441" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "468", "end_pos": "468" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P63141-1.468.468", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P63141-1.479.479", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P63141-1.483.483", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P63141-1.483.483", "start_pos": 483, "end_pos": 483, "uniprot_canonical_ac": "P63141-1", "length": 499, "uniprot_id": "KCNA2_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily A member 2", "refseq_ac": "NP_032443", "refseq_name": "potassium voltage-gated channel subfamily A member 2", "gene_name": "Kcna2", "gene_names_uniprotkb": "Kcna2", "gene_names_refseq": "Akr6a4; Gm10672; Kca1-2; Kcna2; Kv1.2; Mk-2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P63141", "url": "https://www.uniprot.org/uniprotkb/P63141" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Quantitative Profiling of Protein O-GlcNAcylation Sites by an Isotope-Tagged Cleavable Linker.", "journal": "ACS chemical biology", "date": "2018", "authors": "Qin K, Zhu Y, Qin W, Gao J, Shao X, Wang YL, Zhou W, Wang C, Chen X", "evidence": [ { "database": "O-GlcNAc Database", "id": "P63141", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P63141" }, { "database": "O-GlcNAc Atlas", "id": "P63141", "url": "https://oglcnac.org/atlas/detail/P63141" } ], "reference": [ { "type": "PubMed", "id": "30059200", "url": "https://glygen.org/publication/PubMed/30059200" } ] }, { "title": "Characterization and chemoproteomic profiling of protein O-GlcNAcylation in SOD1-G93A mouse model.", "journal": "Molecular medicine (Cambridge, Mass.)", "date": "2025-02-28", "authors": "Hao Yi, Li Zhongzhong, Du Xinyan, Xie Qingsong, Li Dongxiao, Lei Shaoyuan, Guo Yansu", "evidence": [ { "database": "O-GlcNAc Database", "id": "P63141", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P63141" } ], "reference": [ { "type": "PubMed", "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "P63141", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P63141" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "P63141", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P63141" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] } ], "crossref": [ { "id": "30059200", "url": "https://glygen.org/publication/PubMed/30059200", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P63141", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P63141", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "EGVNNSNEDFREENLKTANC", "down_seq": "LANTNYVNITKMLTDV", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr483", "evidence": [ { "id": "30059200", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30059200" }, { "id": "P63141", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P63141" }, { "id": "40021952", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40021952" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "207", "end_pos": "207" }, { "start_pos": "38", "end_pos": "38" }, { "start_pos": "441", "end_pos": "441" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "483", "end_pos": "483" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "402", "end_pos": "402" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "429", "end_pos": "429" }, { "start_pos": "434", "end_pos": "434" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "441", "end_pos": "441" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "468", "end_pos": "468" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P63141-1.468.468", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P63141-1.479.479", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P63141-1.481.481", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P63141-1.402.402", "start_pos": 402, "end_pos": 402, "uniprot_canonical_ac": "P63141-1", "length": 499, "uniprot_id": "KCNA2_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily A member 2", "refseq_ac": "NP_032443", "refseq_name": "potassium voltage-gated channel subfamily A member 2", "gene_name": "Kcna2", "gene_names_uniprotkb": "Kcna2", "gene_names_refseq": "Akr6a4; Gm10672; Kca1-2; Kcna2; Kv1.2; Mk-2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P63141", "url": "https://www.uniprot.org/uniprotkb/P63141" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A new Kv1.2 channelopathy underlying cerebellar ataxia.", "journal": "The Journal of biological chemistry", "date": "2010", "authors": "Xie G, Harrison J, Clapcote SJ, Huang Y, Zhang JY, Wang LY, Roder JC", "evidence": [ { "database": "UniProtKB", "id": "P63141", "url": "https://www.uniprot.org/uniprotkb/P63141" } ], "reference": [ { "type": "PubMed", "id": "20696761", "url": "https://glygen.org/publication/PubMed/20696761" } ] } ], "crossref": [ { "id": "P63141", "url": "https://www.uniprot.org/uniprotkb/P63141", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "20696761", "url": "https://glygen.org/publication/PubMed/20696761", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "I", "start_aa": "I", "up_seq": "PTTIGGKIVGSLCAIAGVLT", "down_seq": "ALPVPVIVSNFNYFYHRETE", "mutagenesis": [ { "sequence_org": "I", "sequence_mut": "T", "comment": "In Pgu; chronic motor incoordination; decreases the number of functional channels at the cell surface.", "evidence": [ { "database": "UniProtKB", "id": "P63141", "url": "https://www.uniprot.org/uniprotkb/P63141" }, { "database": "PubMed", "id": "20696761", "url": "https://glygen.org/publication/PubMed/20696761" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "207", "end_pos": "207" }, { "start_pos": "38", "end_pos": "38" }, { "start_pos": "441", "end_pos": "441" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "483", "end_pos": "483" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "402", "end_pos": "402" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "429", "end_pos": "429" }, { "start_pos": "434", "end_pos": "434" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "441", "end_pos": "441" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "468", "end_pos": "468" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P63141-1.429.429", "start_pos": 429, "end_pos": 429, "uniprot_canonical_ac": "P63141-1", "length": 499, "uniprot_id": "KCNA2_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily A member 2", "refseq_ac": "NP_032443", "refseq_name": "potassium voltage-gated channel subfamily A member 2", "gene_name": "Kcna2", "gene_names_uniprotkb": "Kcna2", "gene_names_refseq": "Akr6a4; Gm10672; Kca1-2; Kcna2; Kv1.2; Mk-2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P63141", "url": "https://www.uniprot.org/uniprotkb/P63141" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain.", "journal": "Journal of proteome research", "date": "2008", "authors": "Ballif BA, Carey GR, Sunyaev SR, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P63141", "url": "https://www.uniprot.org/uniprotkb/P63141" }, { "database": "iPTMnet", "id": "P63141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63141" } ], "reference": [ { "type": "PubMed", "id": "18034455", "url": "https://glygen.org/publication/PubMed/18034455" } ] } ], "crossref": [ { "id": "P63141", "url": "https://www.uniprot.org/uniprotkb/P63141", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18034455", "url": "https://glygen.org/publication/PubMed/18034455", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P63141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63141", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "IVSNFNYFYHRETEGEEQAQ", "down_seq": "LQVTSCPKIPSSPDLKKSRS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "P63141", "url": "https://www.uniprot.org/uniprotkb/P63141" }, { "database": "PubMed", "id": "18034455", "url": "https://glygen.org/publication/PubMed/18034455" }, { "database": "iPTMnet", "id": "P63141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63141" } ], "site_lbl": "Tyr429" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "207", "end_pos": "207" }, { "start_pos": "38", "end_pos": "38" }, { "start_pos": "441", "end_pos": "441" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "483", "end_pos": "483" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "402", "end_pos": "402" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "429", "end_pos": "429" }, { "start_pos": "434", "end_pos": "434" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "441", "end_pos": "441" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "468", "end_pos": "468" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "upstream", "id": "P63141-1.434.434", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P63141-1.440.440", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P63141-1.441.441", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P63141-1.449.449", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P63141-1.434.434", "start_pos": 434, "end_pos": 434, "uniprot_canonical_ac": "P63141-1", "length": 499, "uniprot_id": "KCNA2_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily A member 2", "refseq_ac": "NP_032443", "refseq_name": "potassium voltage-gated channel subfamily A member 2", "gene_name": "Kcna2", "gene_names_uniprotkb": "Kcna2", "gene_names_refseq": "Akr6a4; Gm10672; Kca1-2; Kcna2; Kv1.2; Mk-2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P63141", "url": "https://www.uniprot.org/uniprotkb/P63141" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P63141", "url": "https://www.uniprot.org/uniprotkb/P63141" }, { "database": "iPTMnet", "id": "P63141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63141" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "P63141", "url": "https://www.uniprot.org/uniprotkb/P63141", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P63141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63141", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NYFYHRETEGEEQAQYLQVT", "down_seq": "CPKIPSSPDLKKSRSASTIS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P63141", "url": "https://www.uniprot.org/uniprotkb/P63141" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "P63141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63141" } ], "site_lbl": "Ser434" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "207", "end_pos": "207" }, { "start_pos": "38", "end_pos": "38" }, { "start_pos": "441", "end_pos": "441" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "483", "end_pos": "483" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "402", "end_pos": "402" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "429", "end_pos": "429" }, { "start_pos": "434", "end_pos": "434" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "441", "end_pos": "441" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "468", "end_pos": "468" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "P63141-1.429.429", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P63141-1.440.440", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P63141-1.441.441", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P63141-1.449.449", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P63141-1.440.440", "start_pos": 440, "end_pos": 440, "uniprot_canonical_ac": "P63141-1", "length": 499, "uniprot_id": "KCNA2_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily A member 2", "refseq_ac": "NP_032443", "refseq_name": "potassium voltage-gated channel subfamily A member 2", "gene_name": "Kcna2", "gene_names_uniprotkb": "Kcna2", "gene_names_refseq": "Akr6a4; Gm10672; Kca1-2; Kcna2; Kv1.2; Mk-2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P63141", "url": "https://www.uniprot.org/uniprotkb/P63141" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P63141", "url": "https://www.uniprot.org/uniprotkb/P63141" }, { "database": "iPTMnet", "id": "P63141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63141" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "title": "Trafficking-dependent phosphorylation of Kv1.2 regulates voltage-gated potassium channel cell surface expression.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Yang JW, Vacher H, Park KS, Clark E, Trimmer JS", "evidence": [ { "database": "iPTMnet", "id": "P63141-1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63141-1" } ], "reference": [ { "type": "PubMed", "id": "18056633", "url": "https://glygen.org/publication/PubMed/18056633" } ] }, { "title": "Identification of a molecular locus for normalizing dysregulated GABA release from interneurons in the Fragile X brain.", "journal": "Molecular psychiatry", "date": "2020-09", "authors": "Yang Yi-Mei, Arsenault Jason, Bah Alaji, Krzeminski Mickael, Fekete Adam, Chao Owen Y, Pacey Laura K, Wang Alex, Forman-Kay Julie, Hampson David R, Wang Lu-Yang", "evidence": [ { "database": "iPTMnet", "id": "P63141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63141" } ], "reference": [ { "type": "PubMed", "id": "30224722", "url": "https://glygen.org/publication/PubMed/30224722" } ] } ], "crossref": [ { "id": "P63141", "url": "https://www.uniprot.org/uniprotkb/P63141", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P63141", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P63141", "database": "PRO", "categories": [ "Other" ] }, { "id": "P63141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63141", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18056633", "url": "https://glygen.org/publication/PubMed/18056633", "database": "PubMed", "categories": [ "Other" ] }, { "id": "30224722", "url": "https://glygen.org/publication/PubMed/30224722", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ETEGEEQAQYLQVTSCPKIP", "down_seq": "SPDLKKSRSASTISKSDYME", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P63141", "url": "https://www.uniprot.org/uniprotkb/P63141" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "PRO", "id": "P63141", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P63141" }, { "database": "iPTMnet", "id": "P63141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63141" }, { "database": "PubMed", "id": "18056633", "url": "https://glygen.org/publication/PubMed/18056633" }, { "database": "PubMed", "id": "30224722", "url": "https://glygen.org/publication/PubMed/30224722" } ], "site_lbl": "Ser440" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "207", "end_pos": "207" }, { "start_pos": "38", "end_pos": "38" }, { "start_pos": "441", "end_pos": "441" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "483", "end_pos": "483" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "402", "end_pos": "402" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "429", "end_pos": "429" }, { "start_pos": "434", "end_pos": "434" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "441", "end_pos": "441" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "468", "end_pos": "468" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "P63141-1.429.429", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P63141-1.434.434", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P63141-1.441.441", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P63141-1.449.449", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P63141-1.458.458", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P63141-1.449.449", "start_pos": 449, "end_pos": 449, "uniprot_canonical_ac": "P63141-1", "length": 499, "uniprot_id": "KCNA2_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily A member 2", "refseq_ac": "NP_032443", "refseq_name": "potassium voltage-gated channel subfamily A member 2", "gene_name": "Kcna2", "gene_names_uniprotkb": "Kcna2", "gene_names_refseq": "Akr6a4; Gm10672; Kca1-2; Kcna2; Kv1.2; Mk-2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P63141", "url": "https://www.uniprot.org/uniprotkb/P63141" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P63141", "url": "https://www.uniprot.org/uniprotkb/P63141", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "YLQVTSCPKIPSSPDLKKSR", "down_seq": "ASTISKSDYMEIQEGVNNSN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P63141", "url": "https://www.uniprot.org/uniprotkb/P63141" } ], "site_lbl": "Ser449" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "207", "end_pos": "207" }, { "start_pos": "38", "end_pos": "38" }, { "start_pos": "441", "end_pos": "441" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "483", "end_pos": "483" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "402", "end_pos": "402" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "429", "end_pos": "429" }, { "start_pos": "434", "end_pos": "434" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "441", "end_pos": "441" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "468", "end_pos": "468" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P63141-1.429.429", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P63141-1.434.434", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P63141-1.440.440", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P63141-1.441.441", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P63141-1.458.458", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P63141-1.468.468", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P63141-1.458.458", "start_pos": 458, "end_pos": 458, "uniprot_canonical_ac": "P63141-1", "length": 499, "uniprot_id": "KCNA2_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily A member 2", "refseq_ac": "NP_032443", "refseq_name": "potassium voltage-gated channel subfamily A member 2", "gene_name": "Kcna2", "gene_names_uniprotkb": "Kcna2", "gene_names_refseq": "Akr6a4; Gm10672; Kca1-2; Kcna2; Kv1.2; Mk-2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P63141", "url": "https://www.uniprot.org/uniprotkb/P63141" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P63141", "url": "https://www.uniprot.org/uniprotkb/P63141", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "IPSSPDLKKSRSASTISKSD", "down_seq": "MEIQEGVNNSNEDFREENLK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "P63141", "url": "https://www.uniprot.org/uniprotkb/P63141" } ], "site_lbl": "Tyr458" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "207", "end_pos": "207" }, { "start_pos": "38", "end_pos": "38" }, { "start_pos": "441", "end_pos": "441" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "483", "end_pos": "483" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "402", "end_pos": "402" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "429", "end_pos": "429" }, { "start_pos": "434", "end_pos": "434" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "441", "end_pos": "441" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "468", "end_pos": "468" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P63141-1.440.440", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "downstream", "id": "P63141-1.441.441", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P63141-1.449.449", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P63141-1.468.468", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P63141-1.468.468", "start_pos": 468, "end_pos": 468, "uniprot_canonical_ac": "P63141-1", "length": 499, "uniprot_id": "KCNA2_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily A member 2", "refseq_ac": "NP_032443", "refseq_name": "potassium voltage-gated channel subfamily A member 2", "gene_name": "Kcna2", "gene_names_uniprotkb": "Kcna2", "gene_names_refseq": "Akr6a4; Gm10672; Kca1-2; Kcna2; Kv1.2; Mk-2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P63141", "url": "https://www.uniprot.org/uniprotkb/P63141" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P63141", "url": "https://www.uniprot.org/uniprotkb/P63141" }, { "database": "iPTMnet", "id": "P63141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63141" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "P63141", "url": "https://www.uniprot.org/uniprotkb/P63141", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P63141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63141", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RSASTISKSDYMEIQEGVNN", "down_seq": "NEDFREENLKTANCTLANTN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P63141", "url": "https://www.uniprot.org/uniprotkb/P63141" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "P63141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63141" } ], "site_lbl": "Ser468" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "207", "end_pos": "207" }, { "start_pos": "38", "end_pos": "38" }, { "start_pos": "441", "end_pos": "441" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "483", "end_pos": "483" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "402", "end_pos": "402" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "429", "end_pos": "429" }, { "start_pos": "434", "end_pos": "434" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "441", "end_pos": "441" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "468", "end_pos": "468" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P63141-1.449.449", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P63141-1.458.458", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P63141-1.479.479", "categories": [ "glycosylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P63141-1.481.481", "categories": [ "glycosylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P63141-1.483.483", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q04447-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "Q04447-1", "length": 381, "uniprot_id": "KCRB_MOUSE", "protein_name": "Creatine kinase B-type", "refseq_ac": "NP_067248", "refseq_name": "creatine kinase B-type", "gene_name": "Ckb", "gene_names_uniprotkb": "Ckb; Ckbb", "gene_names_refseq": "B-CK; Bck; CPK-B; Ck-3; Ck3; Ckbb; Ckb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q04447", "url": "https://www.uniprot.org/uniprotkb/Q04447" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "First comprehensive identification of cardiac proteins with putative increased O-GlcNAc levels during pressure overload hypertrophy.", "journal": "PloS one", "date": "2022", "authors": "Zhu Wei Zhong, Palazzo Teresa, Zhou Mowei, Ledee Dolena, Olson Heather M, Pa\u0161a-Toli\u0107 Ljiljana, Olson Aaron K", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q04447", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q04447" } ], "reference": [ { "type": "PubMed", "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343" } ] }, { "title": "Differential Detection of O-GlcNAcylated proteins in the heart using antibodies.", "journal": "Analytical biochemistry", "date": "2023-10-01", "authors": "Narayanan Bhargavi, Zahra Fiddia, Reeves Russell A, Aggarwal Akanksha, O'Meally Robert N, Henry Roger K, Craven Megan, Jacobson Avital, Cole Robert N, Kohr Mark J, Umapathi Priya, Zachara Natasha E", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q04447", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q04447" } ], "reference": [ { "type": "PubMed", "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081" } ] }, { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q04447", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q04447" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] } ], "crossref": [ { "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q04447", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q04447", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "36288343", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36288343" }, { "id": "Q04447", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q04447" }, { "id": "37507081", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37507081" }, { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "130", "end_pos": "138" }, { "start_pos": "283", "end_pos": "283" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "125", "end_pos": "125" }, { "start_pos": "164", "end_pos": "164" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "4", "end_pos": "4" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "Q04447-1.4.4", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q04447-1.130.138", "start_pos": 130, "end_pos": 138, "uniprot_canonical_ac": "Q04447-1", "length": 381, "uniprot_id": "KCRB_MOUSE", "protein_name": "Creatine kinase B-type", "refseq_ac": "NP_067248", "refseq_name": "creatine kinase B-type", "gene_name": "Ckb", "gene_names_uniprotkb": "Ckb; Ckbb", "gene_names_refseq": "B-CK; Bck; CPK-B; Ck-3; Ck3; Ckbb; Ckb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q04447", "url": "https://www.uniprot.org/uniprotkb/Q04447" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Creatine kinase B controls futile creatine cycling in thermogenic fat.", "journal": "Nature", "date": "2021", "authors": "Rahbani JF, Roesler A, Hussain MF, Samborska B, Dykstra CB, Tsai L, Jedrychowski MP, Vergnes L, Reue K, Spiegelman BM, Kazak L", "evidence": [ { "database": "UniProtKB", "id": "Q04447", "url": "https://www.uniprot.org/uniprotkb/Q04447" } ], "reference": [ { "type": "PubMed", "id": "33597756", "url": "https://glygen.org/publication/PubMed/33597756" } ] } ], "crossref": [ { "id": "Q04447", "url": "https://www.uniprot.org/uniprotkb/Q04447", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "33597756", "url": "https://glygen.org/publication/PubMed/33597756", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "RVRTGRSIR", "start_aa": "R", "up_seq": "LNPDNLQGGDDLDPNYVLSS", "down_seq": "GFCLPPHCSRGERRAIEKLA", "mutagenesis": [ { "sequence_org": "RVRTGRSIR", "sequence_mut": "AVATGASIA", "comment": "Abolishes localization to mitochondria in fat cells.", "evidence": [ { "database": "UniProtKB", "id": "Q04447", "url": "https://www.uniprot.org/uniprotkb/Q04447" }, { "database": "PubMed", "id": "33597756", "url": "https://glygen.org/publication/PubMed/33597756" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "130", "end_pos": "138" }, { "start_pos": "283", "end_pos": "283" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "125", "end_pos": "125" }, { "start_pos": "164", "end_pos": "164" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "4", "end_pos": "4" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "Q04447-1.125.125", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q04447-1.283.283", "start_pos": 283, "end_pos": 283, "uniprot_canonical_ac": "Q04447-1", "length": 381, "uniprot_id": "KCRB_MOUSE", "protein_name": "Creatine kinase B-type", "refseq_ac": "NP_067248", "refseq_name": "creatine kinase B-type", "gene_name": "Ckb", "gene_names_uniprotkb": "Ckb; Ckbb", "gene_names_refseq": "B-CK; Bck; CPK-B; Ck-3; Ck3; Ckbb; Ckb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q04447", "url": "https://www.uniprot.org/uniprotkb/Q04447" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Creatine kinase B controls futile creatine cycling in thermogenic fat.", "journal": "Nature", "date": "2021", "authors": "Rahbani JF, Roesler A, Hussain MF, Samborska B, Dykstra CB, Tsai L, Jedrychowski MP, Vergnes L, Reue K, Spiegelman BM, Kazak L", "evidence": [ { "database": "UniProtKB", "id": "Q04447", "url": "https://www.uniprot.org/uniprotkb/Q04447" } ], "reference": [ { "type": "PubMed", "id": "33597756", "url": "https://glygen.org/publication/PubMed/33597756" } ] } ], "crossref": [ { "id": "Q04447", "url": "https://www.uniprot.org/uniprotkb/Q04447", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "33597756", "url": "https://glygen.org/publication/PubMed/33597756", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "C", "start_aa": "C", "up_seq": "LFKSKNYEFMWNPHLGYILT", "down_seq": "PSNLGTGLRAGVHIKLPHLG", "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Abolished creatine kinase activity.", "evidence": [ { "database": "UniProtKB", "id": "Q04447", "url": "https://www.uniprot.org/uniprotkb/Q04447" }, { "database": "PubMed", "id": "33597756", "url": "https://glygen.org/publication/PubMed/33597756" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "130", "end_pos": "138" }, { "start_pos": "283", "end_pos": "283" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "125", "end_pos": "125" }, { "start_pos": "164", "end_pos": "164" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "4", "end_pos": "4" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q04447-1.125.125", "start_pos": 125, "end_pos": 125, "uniprot_canonical_ac": "Q04447-1", "length": 381, "uniprot_id": "KCRB_MOUSE", "protein_name": "Creatine kinase B-type", "refseq_ac": "NP_067248", "refseq_name": "creatine kinase B-type", "gene_name": "Ckb", "gene_names_uniprotkb": "Ckb; Ckbb", "gene_names_refseq": "B-CK; Bck; CPK-B; Ck-3; Ck3; Ckbb; Ckb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q04447", "url": "https://www.uniprot.org/uniprotkb/Q04447" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain.", "journal": "Journal of proteome research", "date": "2008", "authors": "Ballif BA, Carey GR, Sunyaev SR, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q04447", "url": "https://www.uniprot.org/uniprotkb/Q04447" }, { "database": "iPTMnet", "id": "Q04447", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04447" } ], "reference": [ { "type": "PubMed", "id": "18034455", "url": "https://glygen.org/publication/PubMed/18034455" } ] } ], "crossref": [ { "id": "Q04447", "url": "https://www.uniprot.org/uniprotkb/Q04447", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18034455", "url": "https://glygen.org/publication/PubMed/18034455", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q04447", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04447", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "EHKTDLNPDNLQGGDDLDPN", "down_seq": "VLSSRVRTGRSIRGFCLPPH", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "Q04447", "url": "https://www.uniprot.org/uniprotkb/Q04447" }, { "database": "PubMed", "id": "18034455", "url": "https://glygen.org/publication/PubMed/18034455" }, { "database": "iPTMnet", "id": "Q04447", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04447" } ], "site_lbl": "Tyr125" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "130", "end_pos": "138" }, { "start_pos": "283", "end_pos": "283" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "125", "end_pos": "125" }, { "start_pos": "164", "end_pos": "164" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "4", "end_pos": "4" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "upstream", "id": "Q04447-1.130.138", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q04447-1.164.164", "start_pos": 164, "end_pos": 164, "uniprot_canonical_ac": "Q04447-1", "length": 381, "uniprot_id": "KCRB_MOUSE", "protein_name": "Creatine kinase B-type", "refseq_ac": "NP_067248", "refseq_name": "creatine kinase B-type", "gene_name": "Ckb", "gene_names_uniprotkb": "Ckb; Ckbb", "gene_names_refseq": "B-CK; Bck; CPK-B; Ck-3; Ck3; Ckbb; Ckb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q04447", "url": "https://www.uniprot.org/uniprotkb/Q04447" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Quantitative analysis of both protein expression and serine / threonine post-translational modifications through stable isotope labeling with dithiothreitol.", "journal": "Proteomics", "date": "2005", "authors": "Vosseller K, Hansen KC, Chalkley RJ, Trinidad JC, Wells L, Hart GW, Burlingame AL", "evidence": [ { "database": "UniProtKB", "id": "Q04447", "url": "https://www.uniprot.org/uniprotkb/Q04447" }, { "database": "iPTMnet", "id": "Q04447-1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04447-1" } ], "reference": [ { "type": "PubMed", "id": "15648052", "url": "https://glygen.org/publication/PubMed/15648052" } ] } ], "crossref": [ { "id": "Q04447", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=Q04447", "database": "PRO", "categories": [ "Other" ] }, { "id": "Q04447", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04447", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "15648052", "url": "https://glygen.org/publication/PubMed/15648052", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PHCSRGERRAIEKLAVEALS", "down_seq": "LDGDLSGRYYALKSMTEAEQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "PRO", "id": "Q04447", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=Q04447" }, { "database": "iPTMnet", "id": "Q04447", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04447" }, { "database": "PubMed", "id": "15648052", "url": "https://glygen.org/publication/PubMed/15648052" } ], "site_lbl": "Ser164" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "130", "end_pos": "138" }, { "start_pos": "283", "end_pos": "283" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "125", "end_pos": "125" }, { "start_pos": "164", "end_pos": "164" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "4", "end_pos": "4" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q04447-1.199.199", "start_pos": 199, "end_pos": 199, "uniprot_canonical_ac": "Q04447-1", "length": 381, "uniprot_id": "KCRB_MOUSE", "protein_name": "Creatine kinase B-type", "refseq_ac": "NP_067248", "refseq_name": "creatine kinase B-type", "gene_name": "Ckb", "gene_names_uniprotkb": "Ckb; Ckbb", "gene_names_refseq": "B-CK; Bck; CPK-B; Ck-3; Ck3; Ckbb; Ckb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q04447", "url": "https://www.uniprot.org/uniprotkb/Q04447" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q04447", "url": "https://www.uniprot.org/uniprotkb/Q04447" }, { "database": "iPTMnet", "id": "Q04447", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04447" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q04447", "url": "https://www.uniprot.org/uniprotkb/Q04447", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q04447", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04447", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MTEAEQQQLIDDHFLFDKPV", "down_seq": "PLLLASGMARDWPDARGIWH", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q04447", "url": "https://www.uniprot.org/uniprotkb/Q04447" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q04447", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04447" } ], "site_lbl": "Ser199" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "130", "end_pos": "138" }, { "start_pos": "283", "end_pos": "283" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "125", "end_pos": "125" }, { "start_pos": "164", "end_pos": "164" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "4", "end_pos": "4" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q04447-1.309.309", "start_pos": 309, "end_pos": 309, "uniprot_canonical_ac": "Q04447-1", "length": 381, "uniprot_id": "KCRB_MOUSE", "protein_name": "Creatine kinase B-type", "refseq_ac": "NP_067248", "refseq_name": "creatine kinase B-type", "gene_name": "Ckb", "gene_names_uniprotkb": "Ckb; Ckbb", "gene_names_refseq": "B-CK; Bck; CPK-B; Ck-3; Ck3; Ckbb; Ckb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q04447", "url": "https://www.uniprot.org/uniprotkb/Q04447" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q04447", "url": "https://www.uniprot.org/uniprotkb/Q04447", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TGLRAGVHIKLPHLGKHEKF", "down_seq": "EVLKRLRLQKRGTGGVDTAA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q04447", "url": "https://www.uniprot.org/uniprotkb/Q04447" } ], "site_lbl": "Ser309" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "130", "end_pos": "138" }, { "start_pos": "283", "end_pos": "283" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "125", "end_pos": "125" }, { "start_pos": "164", "end_pos": "164" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "4", "end_pos": "4" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "upstream", "id": "Q04447-1.322.322", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q04447-1.322.322", "start_pos": 322, "end_pos": 322, "uniprot_canonical_ac": "Q04447-1", "length": 381, "uniprot_id": "KCRB_MOUSE", "protein_name": "Creatine kinase B-type", "refseq_ac": "NP_067248", "refseq_name": "creatine kinase B-type", "gene_name": "Ckb", "gene_names_uniprotkb": "Ckb; Ckbb", "gene_names_refseq": "B-CK; Bck; CPK-B; Ck-3; Ck3; Ckbb; Ckb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q04447", "url": "https://www.uniprot.org/uniprotkb/Q04447" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q04447", "url": "https://www.uniprot.org/uniprotkb/Q04447" }, { "database": "iPTMnet", "id": "Q04447", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04447" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q04447", "url": "https://www.uniprot.org/uniprotkb/Q04447", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q04447", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04447", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "LGKHEKFSEVLKRLRLQKRG", "down_seq": "GGVDTAAVGGVFDVSNADRL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q04447", "url": "https://www.uniprot.org/uniprotkb/Q04447" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q04447", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04447" } ], "site_lbl": "Thr322" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "130", "end_pos": "138" }, { "start_pos": "283", "end_pos": "283" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "125", "end_pos": "125" }, { "start_pos": "164", "end_pos": "164" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "4", "end_pos": "4" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "Q04447-1.309.309", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q04447-1.35.35", "start_pos": 35, "end_pos": 35, "uniprot_canonical_ac": "Q04447-1", "length": 381, "uniprot_id": "KCRB_MOUSE", "protein_name": "Creatine kinase B-type", "refseq_ac": "NP_067248", "refseq_name": "creatine kinase B-type", "gene_name": "Ckb", "gene_names_uniprotkb": "Ckb; Ckbb", "gene_names_refseq": "B-CK; Bck; CPK-B; Ck-3; Ck3; Ckbb; Ckb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q04447", "url": "https://www.uniprot.org/uniprotkb/Q04447" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q04447", "url": "https://www.uniprot.org/uniprotkb/Q04447" }, { "database": "iPTMnet", "id": "Q04447", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04447" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q04447", "url": "https://www.uniprot.org/uniprotkb/Q04447", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q04447", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04447", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "PAEDEFPDLSSHNNHMAKVL", "down_seq": "PELYAELRAKCTPSGFTLDD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q04447", "url": "https://www.uniprot.org/uniprotkb/Q04447" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q04447", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04447" } ], "site_lbl": "Thr35" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "130", "end_pos": "138" }, { "start_pos": "283", "end_pos": "283" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "125", "end_pos": "125" }, { "start_pos": "164", "end_pos": "164" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "4", "end_pos": "4" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q04447-1.4.4", "start_pos": 4, "end_pos": 4, "uniprot_canonical_ac": "Q04447-1", "length": 381, "uniprot_id": "KCRB_MOUSE", "protein_name": "Creatine kinase B-type", "refseq_ac": "NP_067248", "refseq_name": "creatine kinase B-type", "gene_name": "Ckb", "gene_names_uniprotkb": "Ckb; Ckbb", "gene_names_refseq": "B-CK; Bck; CPK-B; Ck-3; Ck3; Ckbb; Ckb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q04447", "url": "https://www.uniprot.org/uniprotkb/Q04447" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q04447", "url": "https://www.uniprot.org/uniprotkb/Q04447", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MPF", "down_seq": "NSHNTQKLRFPAEDEFPDLS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q04447", "url": "https://www.uniprot.org/uniprotkb/Q04447" } ], "site_lbl": "Ser4" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "130", "end_pos": "138" }, { "start_pos": "283", "end_pos": "283" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "125", "end_pos": "125" }, { "start_pos": "164", "end_pos": "164" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "4", "end_pos": "4" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "Q04447-1.0.0", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q62315-1.247.247", "start_pos": 247, "end_pos": 247, "uniprot_canonical_ac": "Q62315-1", "length": 1234, "uniprot_id": "JARD2_MOUSE", "protein_name": "Protein Jumonji", "refseq_ac": "NP_001191972", "refseq_name": "protein Jumonji isoform 1", "gene_name": "Jarid2", "gene_names_uniprotkb": "Jarid2; Jmj", "gene_names_refseq": "Jarid2; Jmj; jumonji", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q62315", "url": "https://www.uniprot.org/uniprotkb/Q62315" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "GSSRSAREKEPAHKHRSKEA", "down_seq": "PGKEKHSEPRADSRREQASG", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr247", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "247", "end_pos": "247" }, { "start_pos": "763", "end_pos": "763" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "106", "end_pos": "107" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "449", "end_pos": "449" }, { "start_pos": "78", "end_pos": "78" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q62315-1.763.763", "start_pos": 763, "end_pos": 763, "uniprot_canonical_ac": "Q62315-1", "length": 1234, "uniprot_id": "JARD2_MOUSE", "protein_name": "Protein Jumonji", "refseq_ac": "NP_001191972", "refseq_name": "protein Jumonji isoform 1", "gene_name": "Jarid2", "gene_names_uniprotkb": "Jarid2; Jmj", "gene_names_refseq": "Jarid2; Jmj; jumonji", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q62315", "url": "https://www.uniprot.org/uniprotkb/Q62315" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "HHKFHSLPRFEPKNGLVHGV", "down_seq": "PRNGFRSKLKEVGRAPLKTG", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr763", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "247", "end_pos": "247" }, { "start_pos": "763", "end_pos": "763" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "106", "end_pos": "107" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "449", "end_pos": "449" }, { "start_pos": "78", "end_pos": "78" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q62315-1.106.107", "start_pos": 106, "end_pos": 107, "uniprot_canonical_ac": "Q62315-1", "length": 1234, "uniprot_id": "JARD2_MOUSE", "protein_name": "Protein Jumonji", "refseq_ac": "NP_001191972", "refseq_name": "protein Jumonji isoform 1", "gene_name": "Jarid2", "gene_names_uniprotkb": "Jarid2; Jmj", "gene_names_refseq": "Jarid2; Jmj; jumonji", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q62315", "url": "https://www.uniprot.org/uniprotkb/Q62315" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "JUMONJI, a critical factor for cardiac development, functions as a transcriptional repressor.", "journal": "The Journal of biological chemistry", "date": "2003", "authors": "Kim TG, Kraus JC, Chen J, Lee Y", "evidence": [ { "database": "UniProtKB", "id": "Q62315", "url": "https://www.uniprot.org/uniprotkb/Q62315" } ], "reference": [ { "type": "PubMed", "id": "12890668", "url": "https://glygen.org/publication/PubMed/12890668" } ] } ], "crossref": [ { "id": "Q62315", "url": "https://www.uniprot.org/uniprotkb/Q62315", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "12890668", "url": "https://glygen.org/publication/PubMed/12890668", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "RK", "start_aa": "R", "up_seq": "SQVSSTSNDVSSSDFEEGPS", "down_seq": "RPRLQAQRKFAQSQPNSPST", "mutagenesis": [ { "sequence_org": "RK", "sequence_mut": "AA", "comment": "Leads to cytoplasmic relocalization.", "evidence": [ { "database": "UniProtKB", "id": "Q62315", "url": "https://www.uniprot.org/uniprotkb/Q62315" }, { "database": "PubMed", "id": "12890668", "url": "https://glygen.org/publication/PubMed/12890668" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "247", "end_pos": "247" }, { "start_pos": "763", "end_pos": "763" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "106", "end_pos": "107" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "449", "end_pos": "449" }, { "start_pos": "78", "end_pos": "78" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q62315-1.449.449", "start_pos": 449, "end_pos": 449, "uniprot_canonical_ac": "Q62315-1", "length": 1234, "uniprot_id": "JARD2_MOUSE", "protein_name": "Protein Jumonji", "refseq_ac": "NP_001191972", "refseq_name": "protein Jumonji isoform 1", "gene_name": "Jarid2", "gene_names_uniprotkb": "Jarid2; Jmj", "gene_names_refseq": "Jarid2; Jmj; jumonji", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q62315", "url": "https://www.uniprot.org/uniprotkb/Q62315" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q62315", "url": "https://www.uniprot.org/uniprotkb/Q62315", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EGLRNSKRRLEEAQQVDKPQ", "down_seq": "PPKKMKGVAGNAEAPGKKAS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q62315", "url": "https://www.uniprot.org/uniprotkb/Q62315" } ], "site_lbl": "Ser449" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "247", "end_pos": "247" }, { "start_pos": "763", "end_pos": "763" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "106", "end_pos": "107" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "449", "end_pos": "449" }, { "start_pos": "78", "end_pos": "78" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q62315-1.78.78", "start_pos": 78, "end_pos": 78, "uniprot_canonical_ac": "Q62315-1", "length": 1234, "uniprot_id": "JARD2_MOUSE", "protein_name": "Protein Jumonji", "refseq_ac": "NP_001191972", "refseq_name": "protein Jumonji isoform 1", "gene_name": "Jarid2", "gene_names_uniprotkb": "Jarid2; Jmj", "gene_names_refseq": "Jarid2; Jmj; jumonji", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q62315", "url": "https://www.uniprot.org/uniprotkb/Q62315" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q62315", "url": "https://www.uniprot.org/uniprotkb/Q62315", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AVNGLLGNAQAKALGPASEQ", "down_seq": "ENEKDDASQVSSTSNDVSSS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q62315", "url": "https://www.uniprot.org/uniprotkb/Q62315" } ], "site_lbl": "Ser78" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "247", "end_pos": "247" }, { "start_pos": "763", "end_pos": "763" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "106", "end_pos": "107" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "449", "end_pos": "449" }, { "start_pos": "78", "end_pos": "78" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q6P8J7-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "Q6P8J7-1", "length": 419, "uniprot_id": "KCRS_MOUSE", "protein_name": "Creatine kinase S-type, mitochondrial", "refseq_ac": "NP_940807", "refseq_name": "creatine kinase S-type, mitochondrial precursor", "gene_name": "Ckmt2", "gene_names_uniprotkb": "Ckmt2", "gene_names_refseq": "2300008A19Rik; Ckmt2; S-MtCK; ScCKmit; mib-CK", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6P8J7", "url": "https://www.uniprot.org/uniprotkb/Q6P8J7" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Differential Detection of O-GlcNAcylated proteins in the heart using antibodies.", "journal": "Analytical biochemistry", "date": "2023-10-01", "authors": "Narayanan Bhargavi, Zahra Fiddia, Reeves Russell A, Aggarwal Akanksha, O'Meally Robert N, Henry Roger K, Craven Megan, Jacobson Avital, Cole Robert N, Kohr Mark J, Umapathi Priya, Zachara Natasha E", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q6P8J7", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q6P8J7" } ], "reference": [ { "type": "PubMed", "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081" } ] }, { "title": "A reference dataset of O-GlcNAc proteins in quadriceps skeletal muscle from mice.", "journal": "Glycobiology", "date": "2025-02-10", "authors": "Jaiswal Ruchi, Liu Yimin, Petriello Michael, Zhang Xiangmin, Yi Zhengping, Fehl Charlie", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q6P8J7", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q6P8J7" } ], "reference": [ { "type": "PubMed", "id": "39927985", "url": "https://glygen.org/publication/PubMed/39927985" } ] }, { "title": "First comprehensive identification of cardiac proteins with putative increased O-GlcNAc levels during pressure overload hypertrophy.", "journal": "PloS one", "date": "2022", "authors": "Zhu Wei Zhong, Palazzo Teresa, Zhou Mowei, Ledee Dolena, Olson Heather M, Pa\u0161a-Toli\u0107 Ljiljana, Olson Aaron K", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q6P8J7", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q6P8J7" } ], "reference": [ { "type": "PubMed", "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343" } ] }, { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q6P8J7", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q6P8J7" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] } ], "crossref": [ { "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q6P8J7", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q6P8J7", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "39927985", "url": "https://glygen.org/publication/PubMed/39927985", "database": "PubMed", "categories": [ "Other" ] }, { "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "37507081", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37507081" }, { "id": "Q6P8J7", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q6P8J7" }, { "id": "39927985", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39927985" }, { "id": "36288343", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36288343" }, { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" } ] } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "255", "end_pos": "255" }, { "start_pos": "356", "end_pos": "356" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6P8J7-1.255.255", "start_pos": 255, "end_pos": 255, "uniprot_canonical_ac": "Q6P8J7-1", "length": 419, "uniprot_id": "KCRS_MOUSE", "protein_name": "Creatine kinase S-type, mitochondrial", "refseq_ac": "NP_940807", "refseq_name": "creatine kinase S-type, mitochondrial precursor", "gene_name": "Ckmt2", "gene_names_uniprotkb": "Ckmt2", "gene_names_refseq": "2300008A19Rik; Ckmt2; S-MtCK; ScCKmit; mib-CK", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6P8J7", "url": "https://www.uniprot.org/uniprotkb/Q6P8J7" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q6P8J7", "url": "https://www.uniprot.org/uniprotkb/Q6P8J7", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "LLTCAGMARDWPDARGIWHN", "down_seq": "DKTFLIWINEEDHTRVISME", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "Q6P8J7", "url": "https://www.uniprot.org/uniprotkb/Q6P8J7" } ], "site_lbl": "Tyr255" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "255", "end_pos": "255" }, { "start_pos": "356", "end_pos": "356" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q6P8J7-1.356.356", "start_pos": 356, "end_pos": 356, "uniprot_canonical_ac": "Q6P8J7-1", "length": 419, "uniprot_id": "KCRS_MOUSE", "protein_name": "Creatine kinase S-type, mitochondrial", "refseq_ac": "NP_940807", "refseq_name": "creatine kinase S-type, mitochondrial precursor", "gene_name": "Ckmt2", "gene_names_uniprotkb": "Ckmt2", "gene_names_refseq": "2300008A19Rik; Ckmt2; S-MtCK; ScCKmit; mib-CK", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6P8J7", "url": "https://www.uniprot.org/uniprotkb/Q6P8J7" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q6P8J7", "url": "https://www.uniprot.org/uniprotkb/Q6P8J7" }, { "database": "iPTMnet", "id": "Q6P8J7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6P8J7" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q6P8J7", "url": "https://www.uniprot.org/uniprotkb/Q6P8J7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q6P8J7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6P8J7", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "LSKDPRFSKILENLRLQKRG", "down_seq": "GGVDTAAVADVYDISNIDRI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q6P8J7", "url": "https://www.uniprot.org/uniprotkb/Q6P8J7" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q6P8J7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6P8J7" } ], "site_lbl": "Thr356" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "255", "end_pos": "255" }, { "start_pos": "356", "end_pos": "356" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q91V64-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "Q91V64-1", "length": 297, "uniprot_id": "ISOC1_MOUSE", "protein_name": "Isochorismatase domain-containing protein 1", "refseq_ac": "NP_079754", "refseq_name": "isochorismatase domain-containing protein 1", "gene_name": "Isoc1", "gene_names_uniprotkb": "Isoc1", "gene_names_refseq": "2610034N03Rik; Isoc1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q91V64", "url": "https://www.uniprot.org/uniprotkb/Q91V64" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "The Small Molecule 2-Azido-2-deoxy-glucose Is a Metabolic Chemical Reporter of O-GlcNAc Modifications in Mammalian Cells, Revealing an Unexpected Promiscuity of O-GlcNAc Transferase.", "journal": "ACS chemical biology", "date": "2017", "authors": "Zaro BW, Batt AR, Chuh KN, Navarro MX, Pratt MR", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q91V64", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q91V64" } ], "reference": [ { "type": "PubMed", "id": "28135057", "url": "https://glygen.org/publication/PubMed/28135057" } ] } ], "crossref": [ { "id": "28135057", "url": "https://glygen.org/publication/PubMed/28135057", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q91V64", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q91V64", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "28135057", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/28135057" }, { "id": "Q91V64", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q91V64" } ] } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "159", "end_pos": "159" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q91V64-1.159.159", "start_pos": 159, "end_pos": 159, "uniprot_canonical_ac": "Q91V64-1", "length": 297, "uniprot_id": "ISOC1_MOUSE", "protein_name": "Isochorismatase domain-containing protein 1", "refseq_ac": "NP_079754", "refseq_name": "isochorismatase domain-containing protein 1", "gene_name": "Isoc1", "gene_names_uniprotkb": "Isoc1", "gene_names_refseq": "2610034N03Rik; Isoc1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q91V64", "url": "https://www.uniprot.org/uniprotkb/Q91V64" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q91V64", "url": "https://www.uniprot.org/uniprotkb/Q91V64", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "GQRLLQGARILGIPVIITEQ", "down_seq": "PKGLGSTVQEIDLTGVKLVL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "Q91V64", "url": "https://www.uniprot.org/uniprotkb/Q91V64" } ], "site_lbl": "Tyr159" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "159", "end_pos": "159" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9Z329-1.2144.2144", "start_pos": 2144, "end_pos": 2144, "uniprot_canonical_ac": "Q9Z329-1", "length": 2701, "uniprot_id": "ITPR2_MOUSE", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2", "refseq_ac": "NP_034716", "refseq_name": "inositol 1,4,5-trisphosphate-gated calcium channel ITPR2 isoform 2", "gene_name": "Itpr2", "gene_names_uniprotkb": "Itpr2; Itpr5", "gene_names_refseq": "InsP3R-2; InsP3R-5; Ip3r2; Itpr2; Itpr5; insP3R2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "QMLKPGSDPEEGDEALKYYA", "down_seq": "HTAQIEIVRHDRTMEQIVFP", "glycosylation": [ { "glytoucan_ac": "G95177YH", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "YYANHTAQIEIVR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn2144", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2144", "end_pos": "2144" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "2182", "end_pos": "2182" }, { "start_pos": "2456", "end_pos": "2456" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "82", "end_pos": "82" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1351", "end_pos": "1351" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "2498", "end_pos": "2498" }, { "start_pos": "2633", "end_pos": "2633" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "990", "end_pos": "990" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1413", "end_pos": "1413" }, { "start_pos": "2396", "end_pos": "2396" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1160", "end_pos": "1160" }, { "start_pos": "1709", "end_pos": "1709" }, { "start_pos": "1711", "end_pos": "1711" }, { "start_pos": "2607", "end_pos": "2607" }, { "start_pos": "2633", "end_pos": "2633" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "937", "end_pos": "937" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9Z329-1.215.215", "start_pos": 215, "end_pos": 215, "uniprot_canonical_ac": "Q9Z329-1", "length": 2701, "uniprot_id": "ITPR2_MOUSE", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2", "refseq_ac": "NP_034716", "refseq_name": "inositol 1,4,5-trisphosphate-gated calcium channel ITPR2 isoform 2", "gene_name": "Itpr2", "gene_names_uniprotkb": "Itpr2; Itpr5", "gene_names_refseq": "InsP3R-2; InsP3R-5; Ip3r2; Itpr2; Itpr5; insP3R2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "ASNVELLDNPGCKEVNAVNC", "down_seq": "TSWKITLFMKFSSYREDVLK", "glycosylation": [ { "glytoucan_ac": "G23719VF", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "EVNAVNCNTSWK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn215", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2144", "end_pos": "2144" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "2182", "end_pos": "2182" }, { "start_pos": "2456", "end_pos": "2456" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "82", "end_pos": "82" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1351", "end_pos": "1351" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "2498", "end_pos": "2498" }, { "start_pos": "2633", "end_pos": "2633" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "990", "end_pos": "990" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1413", "end_pos": "1413" }, { "start_pos": "2396", "end_pos": "2396" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1160", "end_pos": "1160" }, { "start_pos": "1709", "end_pos": "1709" }, { "start_pos": "1711", "end_pos": "1711" }, { "start_pos": "2607", "end_pos": "2607" }, { "start_pos": "2633", "end_pos": "2633" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "937", "end_pos": "937" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9Z329-1.2182.2182", "start_pos": 2182, "end_pos": 2182, "uniprot_canonical_ac": "Q9Z329-1", "length": 2701, "uniprot_id": "ITPR2_MOUSE", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2", "refseq_ac": "NP_034716", "refseq_name": "inositol 1,4,5-trisphosphate-gated calcium channel ITPR2 isoform 2", "gene_name": "Itpr2", "gene_names_uniprotkb": "Itpr2; Itpr5", "gene_names_refseq": "InsP3R-2; InsP3R-5; Ip3r2; Itpr2; Itpr5; insP3R2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "VFPVPNICEFLTRESKYRVF", "down_seq": "TTERDEQGSKVNDFFQQTED", "glycosylation": [ { "glytoucan_ac": "G92275SC", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "VFNTTER", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn2182", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2144", "end_pos": "2144" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "2182", "end_pos": "2182" }, { "start_pos": "2456", "end_pos": "2456" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "82", "end_pos": "82" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1351", "end_pos": "1351" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "2498", "end_pos": "2498" }, { "start_pos": "2633", "end_pos": "2633" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "990", "end_pos": "990" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1413", "end_pos": "1413" }, { "start_pos": "2396", "end_pos": "2396" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1160", "end_pos": "1160" }, { "start_pos": "1709", "end_pos": "1709" }, { "start_pos": "1711", "end_pos": "1711" }, { "start_pos": "2607", "end_pos": "2607" }, { "start_pos": "2633", "end_pos": "2633" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "937", "end_pos": "937" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9Z329-1.2456.2456", "start_pos": 2456, "end_pos": 2456, "uniprot_canonical_ac": "Q9Z329-1", "length": 2701, "uniprot_id": "ITPR2_MOUSE", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2", "refseq_ac": "NP_034716", "refseq_name": "inositol 1,4,5-trisphosphate-gated calcium channel ITPR2 isoform 2", "gene_name": "Itpr2", "gene_names_uniprotkb": "Itpr2; Itpr5", "gene_names_refseq": "InsP3R-2; InsP3R-5; Ip3r2; Itpr2; Itpr5; insP3R2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "GNHGVPTMTLSSMMETCQKE", "down_seq": "CSPTIPSSNTAGEEGEDGIE", "glycosylation": [ { "glytoucan_ac": "G62765YT", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "ENCSPTIPSSNTAGEEGEDGIER", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn2456", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2144", "end_pos": "2144" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "2182", "end_pos": "2182" }, { "start_pos": "2456", "end_pos": "2456" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "82", "end_pos": "82" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1351", "end_pos": "1351" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "2498", "end_pos": "2498" }, { "start_pos": "2633", "end_pos": "2633" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "990", "end_pos": "990" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1413", "end_pos": "1413" }, { "start_pos": "2396", "end_pos": "2396" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1160", "end_pos": "1160" }, { "start_pos": "1709", "end_pos": "1709" }, { "start_pos": "1711", "end_pos": "1711" }, { "start_pos": "2607", "end_pos": "2607" }, { "start_pos": "2633", "end_pos": "2633" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "937", "end_pos": "937" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9Z329-1.461.461", "start_pos": 461, "end_pos": 461, "uniprot_canonical_ac": "Q9Z329-1", "length": 2701, "uniprot_id": "ITPR2_MOUSE", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2", "refseq_ac": "NP_034716", "refseq_name": "inositol 1,4,5-trisphosphate-gated calcium channel ITPR2 isoform 2", "gene_name": "Itpr2", "gene_names_uniprotkb": "Itpr2; Itpr5", "gene_names_refseq": "InsP3R-2; InsP3R-5; Ip3r2; Itpr2; Itpr5; insP3R2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "DLDFANDANKVLATTVKKLE", "down_seq": "GSITQNERRFVTKLLEDLIF", "glycosylation": [ { "glytoucan_ac": "G80920RR", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "LENGSITQNERR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn461", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2144", "end_pos": "2144" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "2182", "end_pos": "2182" }, { "start_pos": "2456", "end_pos": "2456" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "82", "end_pos": "82" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1351", "end_pos": "1351" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "2498", "end_pos": "2498" }, { "start_pos": "2633", "end_pos": "2633" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "990", "end_pos": "990" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1413", "end_pos": "1413" }, { "start_pos": "2396", "end_pos": "2396" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1160", "end_pos": "1160" }, { "start_pos": "1709", "end_pos": "1709" }, { "start_pos": "1711", "end_pos": "1711" }, { "start_pos": "2607", "end_pos": "2607" }, { "start_pos": "2633", "end_pos": "2633" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "937", "end_pos": "937" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9Z329-1.82.82", "start_pos": 82, "end_pos": 82, "uniprot_canonical_ac": "Q9Z329-1", "length": 2701, "uniprot_id": "ITPR2_MOUSE", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2", "refseq_ac": "NP_034716", "refseq_name": "inositol 1,4,5-trisphosphate-gated calcium channel ITPR2 isoform 2", "gene_name": "Itpr2", "gene_names_uniprotkb": "Itpr2; Itpr5", "gene_names_refseq": "InsP3R-2; InsP3R-5; Ip3r2; Itpr2; Itpr5; insP3R2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "PMNRYSAQKQYWKAKQAKQG", "down_seq": "HTEAALLKKLQHAAELEQKQ", "glycosylation": [ { "glytoucan_ac": "G23719VF", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "QGNHTEAALLKKLQHAAELEQK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn82", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2144", "end_pos": "2144" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "2182", "end_pos": "2182" }, { "start_pos": "2456", "end_pos": "2456" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "82", "end_pos": "82" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1351", "end_pos": "1351" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "2498", "end_pos": "2498" }, { "start_pos": "2633", "end_pos": "2633" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "990", "end_pos": "990" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1413", "end_pos": "1413" }, { "start_pos": "2396", "end_pos": "2396" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1160", "end_pos": "1160" }, { "start_pos": "1709", "end_pos": "1709" }, { "start_pos": "1711", "end_pos": "1711" }, { "start_pos": "2607", "end_pos": "2607" }, { "start_pos": "2633", "end_pos": "2633" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "937", "end_pos": "937" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9Z329-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "Q9Z329-1", "length": 2701, "uniprot_id": "ITPR2_MOUSE", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2", "refseq_ac": "NP_034716", "refseq_name": "inositol 1,4,5-trisphosphate-gated calcium channel ITPR2 isoform 2", "gene_name": "Itpr2", "gene_names_uniprotkb": "Itpr2; Itpr5", "gene_names_refseq": "InsP3R-2; InsP3R-5; Ip3r2; Itpr2; Itpr5; insP3R2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9Z329", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9Z329" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] } ], "crossref": [ { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9Z329", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9Z329", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "Q9Z329", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9Z329" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2144", "end_pos": "2144" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "2182", "end_pos": "2182" }, { "start_pos": "2456", "end_pos": "2456" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "82", "end_pos": "82" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1351", "end_pos": "1351" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "2498", "end_pos": "2498" }, { "start_pos": "2633", "end_pos": "2633" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "990", "end_pos": "990" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1413", "end_pos": "1413" }, { "start_pos": "2396", "end_pos": "2396" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1160", "end_pos": "1160" }, { "start_pos": "1709", "end_pos": "1709" }, { "start_pos": "1711", "end_pos": "1711" }, { "start_pos": "2607", "end_pos": "2607" }, { "start_pos": "2633", "end_pos": "2633" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "937", "end_pos": "937" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9Z329-1.1190.1190", "start_pos": 1190, "end_pos": 1190, "uniprot_canonical_ac": "Q9Z329-1", "length": 2701, "uniprot_id": "ITPR2_MOUSE", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2", "refseq_ac": "NP_034716", "refseq_name": "inositol 1,4,5-trisphosphate-gated calcium channel ITPR2 isoform 2", "gene_name": "Itpr2", "gene_names_uniprotkb": "Itpr2; Itpr5", "gene_names_refseq": "InsP3R-2; InsP3R-5; Ip3r2; Itpr2; Itpr5; insP3R2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Protein kinase A increases type-2 inositol 1,4,5-trisphosphate receptor activity by phosphorylation of serine 937.", "journal": "The Journal of biological chemistry", "date": "2009", "authors": "Betzenhauser MJ, Fike JL, Wagner LE 2nd, Yule DI", "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" }, { "database": "iPTMnet", "id": "Q9Z329", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9Z329" } ], "reference": [ { "type": "PubMed", "id": "19608738", "url": "https://glygen.org/publication/PubMed/19608738" } ] } ], "crossref": [ { "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19608738", "url": "https://glygen.org/publication/PubMed/19608738", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QIDSNKGNNYRIVKEILIRL", "down_seq": "KLCVQNKKCRNQHQRLLKNM", "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "No effect on PKA-mediated phosphorylation. Abolishes PKA-mediated phosphorylation: When associated with A-937; A-990; A-1351 and A-1581.", "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" }, { "database": "PubMed", "id": "19608738", "url": "https://glygen.org/publication/PubMed/19608738" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2144", "end_pos": "2144" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "2182", "end_pos": "2182" }, { "start_pos": "2456", "end_pos": "2456" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "82", "end_pos": "82" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1351", "end_pos": "1351" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "2498", "end_pos": "2498" }, { "start_pos": "2633", "end_pos": "2633" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "990", "end_pos": "990" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1413", "end_pos": "1413" }, { "start_pos": "2396", "end_pos": "2396" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1160", "end_pos": "1160" }, { "start_pos": "1709", "end_pos": "1709" }, { "start_pos": "1711", "end_pos": "1711" }, { "start_pos": "2607", "end_pos": "2607" }, { "start_pos": "2633", "end_pos": "2633" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "937", "end_pos": "937" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9Z329-1.1351.1351", "start_pos": 1351, "end_pos": 1351, "uniprot_canonical_ac": "Q9Z329-1", "length": 2701, "uniprot_id": "ITPR2_MOUSE", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2", "refseq_ac": "NP_034716", "refseq_name": "inositol 1,4,5-trisphosphate-gated calcium channel ITPR2 isoform 2", "gene_name": "Itpr2", "gene_names_uniprotkb": "Itpr2; Itpr5", "gene_names_refseq": "InsP3R-2; InsP3R-5; Ip3r2; Itpr2; Itpr5; insP3R2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Protein kinase A increases type-2 inositol 1,4,5-trisphosphate receptor activity by phosphorylation of serine 937.", "journal": "The Journal of biological chemistry", "date": "2009", "authors": "Betzenhauser MJ, Fike JL, Wagner LE 2nd, Yule DI", "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" }, { "database": "iPTMnet", "id": "Q9Z329", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9Z329" } ], "reference": [ { "type": "PubMed", "id": "19608738", "url": "https://glygen.org/publication/PubMed/19608738" } ] } ], "crossref": [ { "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19608738", "url": "https://glygen.org/publication/PubMed/19608738", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VMTELINGGEDVLIFYNDRA", "down_seq": "FPILLNMMCSERARGDESGP", "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "No effect on PKA-mediated phosphorylation. Abolishes PKA-mediated phosphorylation: When associated with A-937; A-990; A-1190 and A-1581.", "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" }, { "database": "PubMed", "id": "19608738", "url": "https://glygen.org/publication/PubMed/19608738" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2144", "end_pos": "2144" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "2182", "end_pos": "2182" }, { "start_pos": "2456", "end_pos": "2456" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "82", "end_pos": "82" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1351", "end_pos": "1351" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "2498", "end_pos": "2498" }, { "start_pos": "2633", "end_pos": "2633" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "990", "end_pos": "990" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1413", "end_pos": "1413" }, { "start_pos": "2396", "end_pos": "2396" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1160", "end_pos": "1160" }, { "start_pos": "1709", "end_pos": "1709" }, { "start_pos": "1711", "end_pos": "1711" }, { "start_pos": "2607", "end_pos": "2607" }, { "start_pos": "2633", "end_pos": "2633" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "937", "end_pos": "937" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9Z329-1.1581.1581", "start_pos": 1581, "end_pos": 1581, "uniprot_canonical_ac": "Q9Z329-1", "length": 2701, "uniprot_id": "ITPR2_MOUSE", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2", "refseq_ac": "NP_034716", "refseq_name": "inositol 1,4,5-trisphosphate-gated calcium channel ITPR2 isoform 2", "gene_name": "Itpr2", "gene_names_uniprotkb": "Itpr2; Itpr5", "gene_names_refseq": "InsP3R-2; InsP3R-5; Ip3r2; Itpr2; Itpr5; insP3R2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Protein kinase A increases type-2 inositol 1,4,5-trisphosphate receptor activity by phosphorylation of serine 937.", "journal": "The Journal of biological chemistry", "date": "2009", "authors": "Betzenhauser MJ, Fike JL, Wagner LE 2nd, Yule DI", "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" }, { "database": "iPTMnet", "id": "Q9Z329", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9Z329" } ], "reference": [ { "type": "PubMed", "id": "19608738", "url": "https://glygen.org/publication/PubMed/19608738" } ] } ], "crossref": [ { "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19608738", "url": "https://glygen.org/publication/PubMed/19608738", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TLFMKNHSSTVQRAAMGWRL", "down_seq": "ARSGPRFKEALGGPAWDYRN", "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "No effect on PKA-mediated phosphorylation. Abolishes PKA-mediated phosphorylation: When associated with A-937; A-990; A-1190 and A-1351.", "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" }, { "database": "PubMed", "id": "19608738", "url": "https://glygen.org/publication/PubMed/19608738" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2144", "end_pos": "2144" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "2182", "end_pos": "2182" }, { "start_pos": "2456", "end_pos": "2456" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "82", "end_pos": "82" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1351", "end_pos": "1351" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "2498", "end_pos": "2498" }, { "start_pos": "2633", "end_pos": "2633" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "990", "end_pos": "990" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1413", "end_pos": "1413" }, { "start_pos": "2396", "end_pos": "2396" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1160", "end_pos": "1160" }, { "start_pos": "1709", "end_pos": "1709" }, { "start_pos": "1711", "end_pos": "1711" }, { "start_pos": "2607", "end_pos": "2607" }, { "start_pos": "2633", "end_pos": "2633" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "937", "end_pos": "937" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9Z329-1.2498.2498", "start_pos": 2498, "end_pos": 2498, "uniprot_canonical_ac": "Q9Z329-1", "length": 2701, "uniprot_id": "ITPR2_MOUSE", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2", "refseq_ac": "NP_034716", "refseq_name": "inositol 1,4,5-trisphosphate-gated calcium channel ITPR2 isoform 2", "gene_name": "Itpr2", "gene_names_uniprotkb": "Itpr2; Itpr5", "gene_names_refseq": "InsP3R-2; InsP3R-5; Ip3r2; Itpr2; Itpr5; insP3R2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Abolished InsP3R2 function inhibits sweat secretion in both humans and mice.", "journal": "The Journal of clinical investigation", "date": "2014", "authors": "Klar J, Hisatsune C, Baig SM, Tariq M, Johansson AC, Rasool M, Malik NA, Ameur A, Sugiura K, Feuk L, Mikoshiba K, Dahl N", "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" } ], "reference": [ { "type": "PubMed", "id": "25329695", "url": "https://glygen.org/publication/PubMed/25329695" } ] } ], "crossref": [ { "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "25329695", "url": "https://glygen.org/publication/PubMed/25329695", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "G", "start_aa": "G", "up_seq": "TCDTLLMCIVTVLNQGLRNG", "down_seq": "GVGDVLRRPSKDEPLFAARV", "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "S", "comment": "Impairs inositol 1,4,5-trisphosphate-gated calcium channel activity.", "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" }, { "database": "PubMed", "id": "25329695", "url": "https://glygen.org/publication/PubMed/25329695" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2144", "end_pos": "2144" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "2182", "end_pos": "2182" }, { "start_pos": "2456", "end_pos": "2456" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "82", "end_pos": "82" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1351", "end_pos": "1351" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "2498", "end_pos": "2498" }, { "start_pos": "2633", "end_pos": "2633" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "990", "end_pos": "990" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1413", "end_pos": "1413" }, { "start_pos": "2396", "end_pos": "2396" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1160", "end_pos": "1160" }, { "start_pos": "1709", "end_pos": "1709" }, { "start_pos": "1711", "end_pos": "1711" }, { "start_pos": "2607", "end_pos": "2607" }, { "start_pos": "2633", "end_pos": "2633" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "937", "end_pos": "937" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9Z329-1.2633.2633", "start_pos": 2633, "end_pos": 2633, "uniprot_canonical_ac": "Q9Z329-1", "length": 2701, "uniprot_id": "ITPR2_MOUSE", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2", "refseq_ac": "NP_034716", "refseq_name": "inositol 1,4,5-trisphosphate-gated calcium channel ITPR2 isoform 2", "gene_name": "Itpr2", "gene_names_uniprotkb": "Itpr2; Itpr5", "gene_names_refseq": "InsP3R-2; InsP3R-5; Ip3r2; Itpr2; Itpr5; insP3R2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Protein kinase A increases type-2 inositol 1,4,5-trisphosphate receptor activity by phosphorylation of serine 937.", "journal": "The Journal of biological chemistry", "date": "2009", "authors": "Betzenhauser MJ, Fike JL, Wagner LE 2nd, Yule DI", "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" }, { "database": "iPTMnet", "id": "Q9Z329", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9Z329" } ], "reference": [ { "type": "PubMed", "id": "19608738", "url": "https://glygen.org/publication/PubMed/19608738" } ] }, { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" }, { "database": "iPTMnet", "id": "Q9Z329", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9Z329" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19608738", "url": "https://glygen.org/publication/PubMed/19608738", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9Z329", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9Z329", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "YVAQMITEKNLDWFPRMRAM", "down_seq": "LVSNEGDSEQNEIRNLQEKL", "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "No effect on PKA-mediated phosphorylation. Enhanced calcium release on PKA activation.", "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" }, { "database": "PubMed", "id": "19608738", "url": "https://glygen.org/publication/PubMed/19608738" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q9Z329", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9Z329" } ], "site_lbl": "Ser2633" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2144", "end_pos": "2144" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "2182", "end_pos": "2182" }, { "start_pos": "2456", "end_pos": "2456" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "82", "end_pos": "82" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1351", "end_pos": "1351" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "2498", "end_pos": "2498" }, { "start_pos": "2633", "end_pos": "2633" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "990", "end_pos": "990" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1413", "end_pos": "1413" }, { "start_pos": "2396", "end_pos": "2396" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1160", "end_pos": "1160" }, { "start_pos": "1709", "end_pos": "1709" }, { "start_pos": "1711", "end_pos": "1711" }, { "start_pos": "2607", "end_pos": "2607" }, { "start_pos": "2633", "end_pos": "2633" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "937", "end_pos": "937" } ] } ], "categories": [ "mutagenesis_flag", "phosphorylation_flag" ], "glycosylation": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "Q9Z329-1.2636.2636", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9Z329-1.507.507", "start_pos": 507, "end_pos": 507, "uniprot_canonical_ac": "Q9Z329-1", "length": 2701, "uniprot_id": "ITPR2_MOUSE", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2", "refseq_ac": "NP_034716", "refseq_name": "inositol 1,4,5-trisphosphate-gated calcium channel ITPR2 isoform 2", "gene_name": "Itpr2", "gene_names_uniprotkb": "Itpr2; Itpr5", "gene_names_refseq": "InsP3R-2; InsP3R-5; Ip3r2; Itpr2; Itpr5; insP3R2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Molecular cloning of mouse type 2 and type 3 inositol 1,4,5-trisphosphate receptors and identification of a novel type 2 receptor splice variant.", "journal": "The Journal of biological chemistry", "date": "2005", "authors": "Iwai M, Tateishi Y, Hattori M, Mizutani A, Nakamura T, Futatsugi A, Inoue T, Furuichi T, Michikawa T, Mikoshiba K", "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" } ], "reference": [ { "type": "PubMed", "id": "15632133", "url": "https://glygen.org/publication/PubMed/15632133" } ] } ], "crossref": [ { "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "15632133", "url": "https://glygen.org/publication/PubMed/15632133", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "TNNGQDVLDVVITKPNRERQ", "down_seq": "LMREQNILAQVFGILKAPFK", "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Loss of binding activity.", "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" }, { "database": "PubMed", "id": "15632133", "url": "https://glygen.org/publication/PubMed/15632133" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2144", "end_pos": "2144" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "2182", "end_pos": "2182" }, { "start_pos": "2456", "end_pos": "2456" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "82", "end_pos": "82" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1351", "end_pos": "1351" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "2498", "end_pos": "2498" }, { "start_pos": "2633", "end_pos": "2633" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "990", "end_pos": "990" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1413", "end_pos": "1413" }, { "start_pos": "2396", "end_pos": "2396" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1160", "end_pos": "1160" }, { "start_pos": "1709", "end_pos": "1709" }, { "start_pos": "1711", "end_pos": "1711" }, { "start_pos": "2607", "end_pos": "2607" }, { "start_pos": "2633", "end_pos": "2633" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "937", "end_pos": "937" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "Q9Z329-1.510.510", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9Z329-1.510.510", "start_pos": 510, "end_pos": 510, "uniprot_canonical_ac": "Q9Z329-1", "length": 2701, "uniprot_id": "ITPR2_MOUSE", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2", "refseq_ac": "NP_034716", "refseq_name": "inositol 1,4,5-trisphosphate-gated calcium channel ITPR2 isoform 2", "gene_name": "Itpr2", "gene_names_uniprotkb": "Itpr2; Itpr5", "gene_names_refseq": "InsP3R-2; InsP3R-5; Ip3r2; Itpr2; Itpr5; insP3R2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Molecular cloning of mouse type 2 and type 3 inositol 1,4,5-trisphosphate receptors and identification of a novel type 2 receptor splice variant.", "journal": "The Journal of biological chemistry", "date": "2005", "authors": "Iwai M, Tateishi Y, Hattori M, Mizutani A, Nakamura T, Futatsugi A, Inoue T, Furuichi T, Michikawa T, Mikoshiba K", "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" } ], "reference": [ { "type": "PubMed", "id": "15632133", "url": "https://glygen.org/publication/PubMed/15632133" } ] } ], "crossref": [ { "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "15632133", "url": "https://glygen.org/publication/PubMed/15632133", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "GQDVLDVVITKPNRERQKLM", "down_seq": "EQNILAQVFGILKAPFKEKA", "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Loss of binding activity.", "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" }, { "database": "PubMed", "id": "15632133", "url": "https://glygen.org/publication/PubMed/15632133" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2144", "end_pos": "2144" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "2182", "end_pos": "2182" }, { "start_pos": "2456", "end_pos": "2456" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "82", "end_pos": "82" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1351", "end_pos": "1351" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "2498", "end_pos": "2498" }, { "start_pos": "2633", "end_pos": "2633" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "990", "end_pos": "990" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1413", "end_pos": "1413" }, { "start_pos": "2396", "end_pos": "2396" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1160", "end_pos": "1160" }, { "start_pos": "1709", "end_pos": "1709" }, { "start_pos": "1711", "end_pos": "1711" }, { "start_pos": "2607", "end_pos": "2607" }, { "start_pos": "2633", "end_pos": "2633" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "937", "end_pos": "937" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "Q9Z329-1.507.507", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9Z329-1.937.937", "start_pos": 937, "end_pos": 937, "uniprot_canonical_ac": "Q9Z329-1", "length": 2701, "uniprot_id": "ITPR2_MOUSE", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2", "refseq_ac": "NP_034716", "refseq_name": "inositol 1,4,5-trisphosphate-gated calcium channel ITPR2 isoform 2", "gene_name": "Itpr2", "gene_names_uniprotkb": "Itpr2; Itpr5", "gene_names_refseq": "InsP3R-2; InsP3R-5; Ip3r2; Itpr2; Itpr5; insP3R2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Protein kinase A increases type-2 inositol 1,4,5-trisphosphate receptor activity by phosphorylation of serine 937.", "journal": "The Journal of biological chemistry", "date": "2009", "authors": "Betzenhauser MJ, Fike JL, Wagner LE 2nd, Yule DI", "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" }, { "database": "iPTMnet", "id": "Q9Z329", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9Z329" } ], "reference": [ { "type": "PubMed", "id": "19608738", "url": "https://glygen.org/publication/PubMed/19608738" } ] }, { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" }, { "database": "iPTMnet", "id": "Q9Z329", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9Z329" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" }, { "database": "iPTMnet", "id": "Q9Z329", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9Z329" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] } ], "crossref": [ { "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19608738", "url": "https://glygen.org/publication/PubMed/19608738", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9Z329", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9Z329", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VMRTIHGVGEMMTQMVLSRG", "down_seq": "IFPVSVPDAQPIVHPSKQAS", "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Abolishes PKA-mediated phosphorylation. No enhanced calcium release. Abolishes PKA-mediated phosphorylation: When associated with A-990; A-1190; A-1351 and A-1581.", "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" }, { "database": "PubMed", "id": "19608738", "url": "https://glygen.org/publication/PubMed/19608738" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by PKA", "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" }, { "database": "iPTMnet", "id": "Q9Z329", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9Z329" }, { "database": "PubMed", "id": "19608738", "url": "https://glygen.org/publication/PubMed/19608738" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ], "site_lbl": "Ser937" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2144", "end_pos": "2144" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "2182", "end_pos": "2182" }, { "start_pos": "2456", "end_pos": "2456" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "82", "end_pos": "82" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1351", "end_pos": "1351" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "2498", "end_pos": "2498" }, { "start_pos": "2633", "end_pos": "2633" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "990", "end_pos": "990" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1413", "end_pos": "1413" }, { "start_pos": "2396", "end_pos": "2396" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1160", "end_pos": "1160" }, { "start_pos": "1709", "end_pos": "1709" }, { "start_pos": "1711", "end_pos": "1711" }, { "start_pos": "2607", "end_pos": "2607" }, { "start_pos": "2633", "end_pos": "2633" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "937", "end_pos": "937" } ] } ], "categories": [ "mutagenesis_flag", "phosphorylation_flag" ], "glycosylation": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9Z329-1.990.990", "start_pos": 990, "end_pos": 990, "uniprot_canonical_ac": "Q9Z329-1", "length": 2701, "uniprot_id": "ITPR2_MOUSE", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2", "refseq_ac": "NP_034716", "refseq_name": "inositol 1,4,5-trisphosphate-gated calcium channel ITPR2 isoform 2", "gene_name": "Itpr2", "gene_names_uniprotkb": "Itpr2; Itpr5", "gene_names_refseq": "InsP3R-2; InsP3R-5; Ip3r2; Itpr2; Itpr5; insP3R2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Protein kinase A increases type-2 inositol 1,4,5-trisphosphate receptor activity by phosphorylation of serine 937.", "journal": "The Journal of biological chemistry", "date": "2009", "authors": "Betzenhauser MJ, Fike JL, Wagner LE 2nd, Yule DI", "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" }, { "database": "iPTMnet", "id": "Q9Z329", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9Z329" } ], "reference": [ { "type": "PubMed", "id": "19608738", "url": "https://glygen.org/publication/PubMed/19608738" } ] } ], "crossref": [ { "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19608738", "url": "https://glygen.org/publication/PubMed/19608738", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KLKVIEILQFILSVRLDYRI", "down_seq": "YMLSIYKKEFGDNNDNGDPS", "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "No effect on PKA-mediated phosphorylation. Abolishes PKA-mediated phosphorylation: When associated with A-937; A-1190; A-1351 and A-1581.", "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" }, { "database": "PubMed", "id": "19608738", "url": "https://glygen.org/publication/PubMed/19608738" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2144", "end_pos": "2144" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "2182", "end_pos": "2182" }, { "start_pos": "2456", "end_pos": "2456" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "82", "end_pos": "82" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1351", "end_pos": "1351" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "2498", "end_pos": "2498" }, { "start_pos": "2633", "end_pos": "2633" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "990", "end_pos": "990" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1413", "end_pos": "1413" }, { "start_pos": "2396", "end_pos": "2396" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1160", "end_pos": "1160" }, { "start_pos": "1709", "end_pos": "1709" }, { "start_pos": "1711", "end_pos": "1711" }, { "start_pos": "2607", "end_pos": "2607" }, { "start_pos": "2633", "end_pos": "2633" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "937", "end_pos": "937" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9Z329-1.1413.1413", "start_pos": 1413, "end_pos": 1413, "uniprot_canonical_ac": "Q9Z329-1", "length": 2701, "uniprot_id": "ITPR2_MOUSE", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2", "refseq_ac": "NP_034716", "refseq_name": "inositol 1,4,5-trisphosphate-gated calcium channel ITPR2 isoform 2", "gene_name": "Itpr2", "gene_names_uniprotkb": "Itpr2; Itpr5", "gene_names_refseq": "InsP3R-2; InsP3R-5; Ip3r2; Itpr2; Itpr5; insP3R2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs5527909454", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs5527909454", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "TEIKCNSLLPLDDIVRVVTH", "down_seq": "DCIPEVKIAYVNFVNHCYVD", "snv": [ { "evidence": [ { "id": "rs5527909454", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs5527909454" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "D", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (DDC->NDC).", "chr_id": "6", "chr_pos": "146226506", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "D1413", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2144", "end_pos": "2144" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "2182", "end_pos": "2182" }, { "start_pos": "2456", "end_pos": "2456" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "82", "end_pos": "82" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1351", "end_pos": "1351" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "2498", "end_pos": "2498" }, { "start_pos": "2633", "end_pos": "2633" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "990", "end_pos": "990" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1413", "end_pos": "1413" }, { "start_pos": "2396", "end_pos": "2396" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1160", "end_pos": "1160" }, { "start_pos": "1709", "end_pos": "1709" }, { "start_pos": "1711", "end_pos": "1711" }, { "start_pos": "2607", "end_pos": "2607" }, { "start_pos": "2633", "end_pos": "2633" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "937", "end_pos": "937" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9Z329-1.2396.2396", "start_pos": 2396, "end_pos": 2396, "uniprot_canonical_ac": "Q9Z329-1", "length": 2701, "uniprot_id": "ITPR2_MOUSE", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2", "refseq_ac": "NP_034716", "refseq_name": "inositol 1,4,5-trisphosphate-gated calcium channel ITPR2 isoform 2", "gene_name": "Itpr2", "gene_names_uniprotkb": "Itpr2; Itpr5", "gene_names_refseq": "InsP3R-2; InsP3R-5; Ip3r2; Itpr2; Itpr5; insP3R2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388867298", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388867298", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "I", "start_aa": "I", "up_seq": "YREETLLNVIKSVTRNGRSI", "down_seq": "LTAVLALILVYLFSIIGFLF", "snv": [ { "evidence": [ { "id": "rs3388867298", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388867298" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "I", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (ILT->NLT).", "chr_id": "6", "chr_pos": "146072841", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "I2396", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2144", "end_pos": "2144" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "2182", "end_pos": "2182" }, { "start_pos": "2456", "end_pos": "2456" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "82", "end_pos": "82" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1351", "end_pos": "1351" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "2498", "end_pos": "2498" }, { "start_pos": "2633", "end_pos": "2633" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "990", "end_pos": "990" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1413", "end_pos": "1413" }, { "start_pos": "2396", "end_pos": "2396" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1160", "end_pos": "1160" }, { "start_pos": "1709", "end_pos": "1709" }, { "start_pos": "1711", "end_pos": "1711" }, { "start_pos": "2607", "end_pos": "2607" }, { "start_pos": "2633", "end_pos": "2633" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "937", "end_pos": "937" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9Z329-1.1160.1160", "start_pos": 1160, "end_pos": 1160, "uniprot_canonical_ac": "Q9Z329-1", "length": 2701, "uniprot_id": "ITPR2_MOUSE", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2", "refseq_ac": "NP_034716", "refseq_name": "inositol 1,4,5-trisphosphate-gated calcium channel ITPR2 isoform 2", "gene_name": "Itpr2", "gene_names_uniprotkb": "Itpr2; Itpr5", "gene_names_refseq": "InsP3R-2; InsP3R-5; Ip3r2; Itpr2; Itpr5; insP3R2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DVGEGQAKGGEEANEESNLL", "down_seq": "PVQDGAKTPQIDSNKGNNYR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" } ], "site_lbl": "Ser1160" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2144", "end_pos": "2144" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "2182", "end_pos": "2182" }, { "start_pos": "2456", "end_pos": "2456" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "82", "end_pos": "82" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1351", "end_pos": "1351" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "2498", "end_pos": "2498" }, { "start_pos": "2633", "end_pos": "2633" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "990", "end_pos": "990" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1413", "end_pos": "1413" }, { "start_pos": "2396", "end_pos": "2396" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1160", "end_pos": "1160" }, { "start_pos": "1709", "end_pos": "1709" }, { "start_pos": "1711", "end_pos": "1711" }, { "start_pos": "2607", "end_pos": "2607" }, { "start_pos": "2633", "end_pos": "2633" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "937", "end_pos": "937" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9Z329-1.1709.1709", "start_pos": 1709, "end_pos": 1709, "uniprot_canonical_ac": "Q9Z329-1", "length": 2701, "uniprot_id": "ITPR2_MOUSE", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2", "refseq_ac": "NP_034716", "refseq_name": "inositol 1,4,5-trisphosphate-gated calcium channel ITPR2 isoform 2", "gene_name": "Itpr2", "gene_names_uniprotkb": "Itpr2; Itpr5", "gene_names_refseq": "InsP3R-2; InsP3R-5; Ip3r2; Itpr2; Itpr5; insP3R2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" }, { "database": "iPTMnet", "id": "Q9Z329", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9Z329" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9Z329", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9Z329", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MEEGSTLRRILLNRYFKGDH", "down_seq": "ISVNGPLSGAYAKTAQVGGS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q9Z329", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9Z329" } ], "site_lbl": "Ser1709" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2144", "end_pos": "2144" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "2182", "end_pos": "2182" }, { "start_pos": "2456", "end_pos": "2456" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "82", "end_pos": "82" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1351", "end_pos": "1351" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "2498", "end_pos": "2498" }, { "start_pos": "2633", "end_pos": "2633" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "990", "end_pos": "990" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1413", "end_pos": "1413" }, { "start_pos": "2396", "end_pos": "2396" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1160", "end_pos": "1160" }, { "start_pos": "1709", "end_pos": "1709" }, { "start_pos": "1711", "end_pos": "1711" }, { "start_pos": "2607", "end_pos": "2607" }, { "start_pos": "2633", "end_pos": "2633" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "937", "end_pos": "937" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "Q9Z329-1.1711.1711", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9Z329-1.1711.1711", "start_pos": 1711, "end_pos": 1711, "uniprot_canonical_ac": "Q9Z329-1", "length": 2701, "uniprot_id": "ITPR2_MOUSE", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2", "refseq_ac": "NP_034716", "refseq_name": "inositol 1,4,5-trisphosphate-gated calcium channel ITPR2 isoform 2", "gene_name": "Itpr2", "gene_names_uniprotkb": "Itpr2; Itpr5", "gene_names_refseq": "InsP3R-2; InsP3R-5; Ip3r2; Itpr2; Itpr5; insP3R2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" }, { "database": "iPTMnet", "id": "Q9Z329", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9Z329" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9Z329", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9Z329", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EGSTLRRILLNRYFKGDHSI", "down_seq": "VNGPLSGAYAKTAQVGGSFS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q9Z329", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9Z329" } ], "site_lbl": "Ser1711" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2144", "end_pos": "2144" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "2182", "end_pos": "2182" }, { "start_pos": "2456", "end_pos": "2456" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "82", "end_pos": "82" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1351", "end_pos": "1351" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "2498", "end_pos": "2498" }, { "start_pos": "2633", "end_pos": "2633" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "990", "end_pos": "990" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1413", "end_pos": "1413" }, { "start_pos": "2396", "end_pos": "2396" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1160", "end_pos": "1160" }, { "start_pos": "1709", "end_pos": "1709" }, { "start_pos": "1711", "end_pos": "1711" }, { "start_pos": "2607", "end_pos": "2607" }, { "start_pos": "2633", "end_pos": "2633" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "937", "end_pos": "937" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "Q9Z329-1.1709.1709", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9Z329-1.2607.2607", "start_pos": 2607, "end_pos": 2607, "uniprot_canonical_ac": "Q9Z329-1", "length": 2701, "uniprot_id": "ITPR2_MOUSE", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2", "refseq_ac": "NP_034716", "refseq_name": "inositol 1,4,5-trisphosphate-gated calcium channel ITPR2 isoform 2", "gene_name": "Itpr2", "gene_names_uniprotkb": "Itpr2; Itpr5", "gene_names_refseq": "InsP3R-2; InsP3R-5; Ip3r2; Itpr2; Itpr5; insP3R2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "HNMWHYLYFIVLVKVKDPTE", "down_seq": "TGPESYVAQMITEKNLDWFP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" } ], "site_lbl": "Tyr2607" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2144", "end_pos": "2144" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "2182", "end_pos": "2182" }, { "start_pos": "2456", "end_pos": "2456" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "82", "end_pos": "82" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1351", "end_pos": "1351" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "2498", "end_pos": "2498" }, { "start_pos": "2633", "end_pos": "2633" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "990", "end_pos": "990" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1413", "end_pos": "1413" }, { "start_pos": "2396", "end_pos": "2396" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1160", "end_pos": "1160" }, { "start_pos": "1709", "end_pos": "1709" }, { "start_pos": "1711", "end_pos": "1711" }, { "start_pos": "2607", "end_pos": "2607" }, { "start_pos": "2633", "end_pos": "2633" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "937", "end_pos": "937" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9Z329-1.2636.2636", "start_pos": 2636, "end_pos": 2636, "uniprot_canonical_ac": "Q9Z329-1", "length": 2701, "uniprot_id": "ITPR2_MOUSE", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2", "refseq_ac": "NP_034716", "refseq_name": "inositol 1,4,5-trisphosphate-gated calcium channel ITPR2 isoform 2", "gene_name": "Itpr2", "gene_names_uniprotkb": "Itpr2; Itpr5", "gene_names_refseq": "InsP3R-2; InsP3R-5; Ip3r2; Itpr2; Itpr5; insP3R2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" }, { "database": "iPTMnet", "id": "Q9Z329", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9Z329" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9Z329", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9Z329", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QMITEKNLDWFPRMRAMSLV", "down_seq": "NEGDSEQNEIRNLQEKLEST", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9Z329", "url": "https://www.uniprot.org/uniprotkb/Q9Z329" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q9Z329", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9Z329" } ], "site_lbl": "Ser2636" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2144", "end_pos": "2144" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "2182", "end_pos": "2182" }, { "start_pos": "2456", "end_pos": "2456" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "82", "end_pos": "82" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1351", "end_pos": "1351" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "2498", "end_pos": "2498" }, { "start_pos": "2633", "end_pos": "2633" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "990", "end_pos": "990" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1413", "end_pos": "1413" }, { "start_pos": "2396", "end_pos": "2396" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1160", "end_pos": "1160" }, { "start_pos": "1709", "end_pos": "1709" }, { "start_pos": "1711", "end_pos": "1711" }, { "start_pos": "2607", "end_pos": "2607" }, { "start_pos": "2633", "end_pos": "2633" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "937", "end_pos": "937" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "Q9Z329-1.2633.2633", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q62074-1.541.541", "start_pos": 541, "end_pos": 541, "uniprot_canonical_ac": "Q62074-1", "length": 595, "uniprot_id": "KPCI_MOUSE", "protein_name": "Protein kinase C iota type", "refseq_ac": "NP_032883", "refseq_name": "protein kinase C iota type isoform 1", "gene_name": "Prkci", "gene_names_uniprotkb": "Prkci; Pkcl", "gene_names_refseq": "2310021H13Rik; PKClambda; Pkci; Pkcl; Prkci; Prkcl; aPKClambda; mKIAA4165", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "FRNVDWDMMEQKQVVPPFKP", "down_seq": "ISGEFGLDNFDSQFTNEPVQ", "glycosylation": [ { "glytoucan_ac": "G01650EU", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "PNISGEFGLDNFDSQFTNEPVQLTPDDDDIVR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn541", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "541", "end_pos": "541" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "27", "end_pos": "27" }, { "start_pos": "28", "end_pos": "28" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "70", "end_pos": "70" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "76", "end_pos": "76" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "85", "end_pos": "85" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "264", "end_pos": "264" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "333", "end_pos": "333" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "563", "end_pos": "563" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q62074-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "Q62074-1", "length": 595, "uniprot_id": "KPCI_MOUSE", "protein_name": "Protein kinase C iota type", "refseq_ac": "NP_032883", "refseq_name": "protein kinase C iota type isoform 1", "gene_name": "Prkci", "gene_names_uniprotkb": "Prkci; Pkcl", "gene_names_refseq": "2310021H13Rik; PKClambda; Pkci; Pkcl; Prkci; Prkcl; aPKClambda; mKIAA4165", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Changes in metabolic chemical reporter structure yield a selective probe of O-GlcNAc modification.", "journal": "Journal of the American Chemical Society", "date": "2014", "authors": "Chuh KN, Zaro BW, Piller F, Piller V, Pratt MR", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q62074", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q62074" } ], "reference": [ { "type": "PubMed", "id": "25153642", "url": "https://glygen.org/publication/PubMed/25153642" } ] } ], "crossref": [ { "id": "25153642", "url": "https://glygen.org/publication/PubMed/25153642", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q62074", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q62074", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "25153642", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/25153642" }, { "id": "Q62074", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q62074" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "541", "end_pos": "541" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "27", "end_pos": "27" }, { "start_pos": "28", "end_pos": "28" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "70", "end_pos": "70" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "76", "end_pos": "76" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "85", "end_pos": "85" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "264", "end_pos": "264" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "333", "end_pos": "333" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "563", "end_pos": "563" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "Q62074-1.3.3", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q62074-1.7.7", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q62074-1.8.8", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q62074-1.9.9", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q62074-1.27.27", "start_pos": 27, "end_pos": 27, "uniprot_canonical_ac": "Q62074-1", "length": 595, "uniprot_id": "KPCI_MOUSE", "protein_name": "Protein kinase C iota type", "refseq_ac": "NP_032883", "refseq_name": "protein kinase C iota type isoform 1", "gene_name": "Prkci", "gene_names_uniprotkb": "Prkci; Pkcl", "gene_names_refseq": "2310021H13Rik; PKClambda; Pkci; Pkcl; Prkci; Prkcl; aPKClambda; mKIAA4165", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Interaction codes within the family of mammalian Phox and Bem1p domain-containing proteins.", "journal": "The Journal of biological chemistry", "date": "2003", "authors": "Lamark T, Perander M, Outzen H, Kristiansen K, Overvatn A, Michaelsen E, Bjorkoy G, Johansen T", "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" } ], "reference": [ { "type": "PubMed", "id": "12813044", "url": "https://glygen.org/publication/PubMed/12813044" } ] } ], "crossref": [ { "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "12813044", "url": "https://glygen.org/publication/PubMed/12813044", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "SSTMSHTVACGGGGDHSHQV", "down_seq": "VKAYYRGDIMITHFEPSISF", "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "No effect on interaction with SQSTM1.", "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" }, { "database": "PubMed", "id": "12813044", "url": "https://glygen.org/publication/PubMed/12813044" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "541", "end_pos": "541" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "27", "end_pos": "27" }, { "start_pos": "28", "end_pos": "28" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "70", "end_pos": "70" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "76", "end_pos": "76" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "85", "end_pos": "85" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "264", "end_pos": "264" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "333", "end_pos": "333" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "563", "end_pos": "563" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "Q62074-1.7.7", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "downstream", "id": "Q62074-1.8.8", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "downstream", "id": "Q62074-1.9.9", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q62074-1.28.28", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q62074-1.29.29", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q62074-1.28.28", "start_pos": 28, "end_pos": 28, "uniprot_canonical_ac": "Q62074-1", "length": 595, "uniprot_id": "KPCI_MOUSE", "protein_name": "Protein kinase C iota type", "refseq_ac": "NP_032883", "refseq_name": "protein kinase C iota type isoform 1", "gene_name": "Prkci", "gene_names_uniprotkb": "Prkci; Pkcl", "gene_names_refseq": "2310021H13Rik; PKClambda; Pkci; Pkcl; Prkci; Prkcl; aPKClambda; mKIAA4165", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Interaction codes within the family of mammalian Phox and Bem1p domain-containing proteins.", "journal": "The Journal of biological chemistry", "date": "2003", "authors": "Lamark T, Perander M, Outzen H, Kristiansen K, Overvatn A, Michaelsen E, Bjorkoy G, Johansen T", "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" } ], "reference": [ { "type": "PubMed", "id": "12813044", "url": "https://glygen.org/publication/PubMed/12813044" } ] } ], "crossref": [ { "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "12813044", "url": "https://glygen.org/publication/PubMed/12813044", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "V", "start_aa": "V", "up_seq": "STMSHTVACGGGGDHSHQVR", "down_seq": "KAYYRGDIMITHFEPSISFE", "mutagenesis": [ { "sequence_org": "V", "sequence_mut": "A", "comment": "No effect on interaction with SQSTM1; when associated with A-29.", "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" }, { "database": "PubMed", "id": "12813044", "url": "https://glygen.org/publication/PubMed/12813044" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "541", "end_pos": "541" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "27", "end_pos": "27" }, { "start_pos": "28", "end_pos": "28" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "70", "end_pos": "70" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "76", "end_pos": "76" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "85", "end_pos": "85" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "264", "end_pos": "264" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "333", "end_pos": "333" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "563", "end_pos": "563" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "Q62074-1.8.8", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "downstream", "id": "Q62074-1.9.9", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q62074-1.27.27", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q62074-1.29.29", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q62074-1.29.29", "start_pos": 29, "end_pos": 29, "uniprot_canonical_ac": "Q62074-1", "length": 595, "uniprot_id": "KPCI_MOUSE", "protein_name": "Protein kinase C iota type", "refseq_ac": "NP_032883", "refseq_name": "protein kinase C iota type isoform 1", "gene_name": "Prkci", "gene_names_uniprotkb": "Prkci; Pkcl", "gene_names_refseq": "2310021H13Rik; PKClambda; Pkci; Pkcl; Prkci; Prkcl; aPKClambda; mKIAA4165", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Interaction codes within the family of mammalian Phox and Bem1p domain-containing proteins.", "journal": "The Journal of biological chemistry", "date": "2003", "authors": "Lamark T, Perander M, Outzen H, Kristiansen K, Overvatn A, Michaelsen E, Bjorkoy G, Johansen T", "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" } ], "reference": [ { "type": "PubMed", "id": "12813044", "url": "https://glygen.org/publication/PubMed/12813044" } ] } ], "crossref": [ { "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "12813044", "url": "https://glygen.org/publication/PubMed/12813044", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "TMSHTVACGGGGDHSHQVRV", "down_seq": "AYYRGDIMITHFEPSISFEG", "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "No effect on interaction with SQSTM1; when associated with A-118.", "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" }, { "database": "PubMed", "id": "12813044", "url": "https://glygen.org/publication/PubMed/12813044" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "541", "end_pos": "541" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "27", "end_pos": "27" }, { "start_pos": "28", "end_pos": "28" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "70", "end_pos": "70" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "76", "end_pos": "76" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "85", "end_pos": "85" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "264", "end_pos": "264" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "333", "end_pos": "333" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "563", "end_pos": "563" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "Q62074-1.9.9", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q62074-1.27.27", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q62074-1.28.28", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q62074-1.70.70", "start_pos": 70, "end_pos": 70, "uniprot_canonical_ac": "Q62074-1", "length": 595, "uniprot_id": "KPCI_MOUSE", "protein_name": "Protein kinase C iota type", "refseq_ac": "NP_032883", "refseq_name": "protein kinase C iota type isoform 1", "gene_name": "Prkci", "gene_names_uniprotkb": "Prkci; Pkcl", "gene_names_refseq": "2310021H13Rik; PKClambda; Pkci; Pkcl; Prkci; Prkcl; aPKClambda; mKIAA4165", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Interaction codes within the family of mammalian Phox and Bem1p domain-containing proteins.", "journal": "The Journal of biological chemistry", "date": "2003", "authors": "Lamark T, Perander M, Outzen H, Kristiansen K, Overvatn A, Michaelsen E, Bjorkoy G, Johansen T", "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" } ], "reference": [ { "type": "PubMed", "id": "12813044", "url": "https://glygen.org/publication/PubMed/12813044" } ] } ], "crossref": [ { "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "12813044", "url": "https://glygen.org/publication/PubMed/12813044", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "W", "start_aa": "W", "up_seq": "LCSEVRDMCSFDNEQPFTMK", "down_seq": "IDEEGDPCTVSSQLELEEAF", "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "A", "comment": "Loss of interaction with SQSTM1.", "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" }, { "database": "PubMed", "id": "12813044", "url": "https://glygen.org/publication/PubMed/12813044" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "541", "end_pos": "541" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "27", "end_pos": "27" }, { "start_pos": "28", "end_pos": "28" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "70", "end_pos": "70" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "76", "end_pos": "76" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "85", "end_pos": "85" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "264", "end_pos": "264" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "333", "end_pos": "333" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "563", "end_pos": "563" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "Q62074-1.72.72", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q62074-1.74.74", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q62074-1.76.76", "categories": [ "mutagenesis_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q62074-1.83.83", "categories": [ "mutagenesis_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q62074-1.85.85", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q62074-1.72.72", "start_pos": 72, "end_pos": 72, "uniprot_canonical_ac": "Q62074-1", "length": 595, "uniprot_id": "KPCI_MOUSE", "protein_name": "Protein kinase C iota type", "refseq_ac": "NP_032883", "refseq_name": "protein kinase C iota type isoform 1", "gene_name": "Prkci", "gene_names_uniprotkb": "Prkci; Pkcl", "gene_names_refseq": "2310021H13Rik; PKClambda; Pkci; Pkcl; Prkci; Prkcl; aPKClambda; mKIAA4165", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Interaction codes within the family of mammalian Phox and Bem1p domain-containing proteins.", "journal": "The Journal of biological chemistry", "date": "2003", "authors": "Lamark T, Perander M, Outzen H, Kristiansen K, Overvatn A, Michaelsen E, Bjorkoy G, Johansen T", "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" } ], "reference": [ { "type": "PubMed", "id": "12813044", "url": "https://glygen.org/publication/PubMed/12813044" } ] } ], "crossref": [ { "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "12813044", "url": "https://glygen.org/publication/PubMed/12813044", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "SEVRDMCSFDNEQPFTMKWI", "down_seq": "EEGDPCTVSSQLELEEAFRL", "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Loss of interaction with SQSTM1.", "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" }, { "database": "PubMed", "id": "12813044", "url": "https://glygen.org/publication/PubMed/12813044" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "541", "end_pos": "541" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "27", "end_pos": "27" }, { "start_pos": "28", "end_pos": "28" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "70", "end_pos": "70" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "76", "end_pos": "76" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "85", "end_pos": "85" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "264", "end_pos": "264" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "333", "end_pos": "333" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "563", "end_pos": "563" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "Q62074-1.70.70", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q62074-1.74.74", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q62074-1.76.76", "categories": [ "mutagenesis_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q62074-1.83.83", "categories": [ "mutagenesis_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q62074-1.85.85", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q62074-1.74.74", "start_pos": 74, "end_pos": 74, "uniprot_canonical_ac": "Q62074-1", "length": 595, "uniprot_id": "KPCI_MOUSE", "protein_name": "Protein kinase C iota type", "refseq_ac": "NP_032883", "refseq_name": "protein kinase C iota type isoform 1", "gene_name": "Prkci", "gene_names_uniprotkb": "Prkci; Pkcl", "gene_names_refseq": "2310021H13Rik; PKClambda; Pkci; Pkcl; Prkci; Prkcl; aPKClambda; mKIAA4165", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Interaction codes within the family of mammalian Phox and Bem1p domain-containing proteins.", "journal": "The Journal of biological chemistry", "date": "2003", "authors": "Lamark T, Perander M, Outzen H, Kristiansen K, Overvatn A, Michaelsen E, Bjorkoy G, Johansen T", "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" } ], "reference": [ { "type": "PubMed", "id": "12813044", "url": "https://glygen.org/publication/PubMed/12813044" } ] } ], "crossref": [ { "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "12813044", "url": "https://glygen.org/publication/PubMed/12813044", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "E", "start_aa": "E", "up_seq": "VRDMCSFDNEQPFTMKWIDE", "down_seq": "GDPCTVSSQLELEEAFRLYE", "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Loss of interaction with SQSTM1.", "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" }, { "database": "PubMed", "id": "12813044", "url": "https://glygen.org/publication/PubMed/12813044" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "541", "end_pos": "541" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "27", "end_pos": "27" }, { "start_pos": "28", "end_pos": "28" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "70", "end_pos": "70" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "76", "end_pos": "76" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "85", "end_pos": "85" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "264", "end_pos": "264" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "333", "end_pos": "333" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "563", "end_pos": "563" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "Q62074-1.70.70", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q62074-1.72.72", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q62074-1.76.76", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q62074-1.83.83", "categories": [ "mutagenesis_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q62074-1.85.85", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q62074-1.76.76", "start_pos": 76, "end_pos": 76, "uniprot_canonical_ac": "Q62074-1", "length": 595, "uniprot_id": "KPCI_MOUSE", "protein_name": "Protein kinase C iota type", "refseq_ac": "NP_032883", "refseq_name": "protein kinase C iota type isoform 1", "gene_name": "Prkci", "gene_names_uniprotkb": "Prkci; Pkcl", "gene_names_refseq": "2310021H13Rik; PKClambda; Pkci; Pkcl; Prkci; Prkcl; aPKClambda; mKIAA4165", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Interaction codes within the family of mammalian Phox and Bem1p domain-containing proteins.", "journal": "The Journal of biological chemistry", "date": "2003", "authors": "Lamark T, Perander M, Outzen H, Kristiansen K, Overvatn A, Michaelsen E, Bjorkoy G, Johansen T", "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" } ], "reference": [ { "type": "PubMed", "id": "12813044", "url": "https://glygen.org/publication/PubMed/12813044" } ] } ], "crossref": [ { "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "12813044", "url": "https://glygen.org/publication/PubMed/12813044", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "DMCSFDNEQPFTMKWIDEEG", "down_seq": "PCTVSSQLELEEAFRLYELN", "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Loss of interaction with SQSTM1.", "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" }, { "database": "PubMed", "id": "12813044", "url": "https://glygen.org/publication/PubMed/12813044" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "541", "end_pos": "541" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "27", "end_pos": "27" }, { "start_pos": "28", "end_pos": "28" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "70", "end_pos": "70" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "76", "end_pos": "76" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "85", "end_pos": "85" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "264", "end_pos": "264" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "333", "end_pos": "333" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "563", "end_pos": "563" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "Q62074-1.70.70", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q62074-1.72.72", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q62074-1.74.74", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q62074-1.83.83", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q62074-1.85.85", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q62074-1.83.83", "start_pos": 83, "end_pos": 83, "uniprot_canonical_ac": "Q62074-1", "length": 595, "uniprot_id": "KPCI_MOUSE", "protein_name": "Protein kinase C iota type", "refseq_ac": "NP_032883", "refseq_name": "protein kinase C iota type isoform 1", "gene_name": "Prkci", "gene_names_uniprotkb": "Prkci; Pkcl", "gene_names_refseq": "2310021H13Rik; PKClambda; Pkci; Pkcl; Prkci; Prkcl; aPKClambda; mKIAA4165", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Interaction codes within the family of mammalian Phox and Bem1p domain-containing proteins.", "journal": "The Journal of biological chemistry", "date": "2003", "authors": "Lamark T, Perander M, Outzen H, Kristiansen K, Overvatn A, Michaelsen E, Bjorkoy G, Johansen T", "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" } ], "reference": [ { "type": "PubMed", "id": "12813044", "url": "https://glygen.org/publication/PubMed/12813044" } ] } ], "crossref": [ { "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "12813044", "url": "https://glygen.org/publication/PubMed/12813044", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Q", "start_aa": "Q", "up_seq": "EQPFTMKWIDEEGDPCTVSS", "down_seq": "LELEEAFRLYELNKDSELLI", "mutagenesis": [ { "sequence_org": "Q", "sequence_mut": "A", "comment": "No effect on interaction with SQSTM1.", "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" }, { "database": "PubMed", "id": "12813044", "url": "https://glygen.org/publication/PubMed/12813044" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "541", "end_pos": "541" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "27", "end_pos": "27" }, { "start_pos": "28", "end_pos": "28" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "70", "end_pos": "70" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "76", "end_pos": "76" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "85", "end_pos": "85" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "264", "end_pos": "264" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "333", "end_pos": "333" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "563", "end_pos": "563" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "Q62074-1.70.70", "categories": [ "mutagenesis_flag" ] }, { "distance": 11, "direction": "downstream", "id": "Q62074-1.72.72", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "downstream", "id": "Q62074-1.74.74", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "downstream", "id": "Q62074-1.76.76", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q62074-1.85.85", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q62074-1.85.85", "start_pos": 85, "end_pos": 85, "uniprot_canonical_ac": "Q62074-1", "length": 595, "uniprot_id": "KPCI_MOUSE", "protein_name": "Protein kinase C iota type", "refseq_ac": "NP_032883", "refseq_name": "protein kinase C iota type isoform 1", "gene_name": "Prkci", "gene_names_uniprotkb": "Prkci; Pkcl", "gene_names_refseq": "2310021H13Rik; PKClambda; Pkci; Pkcl; Prkci; Prkcl; aPKClambda; mKIAA4165", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Interaction codes within the family of mammalian Phox and Bem1p domain-containing proteins.", "journal": "The Journal of biological chemistry", "date": "2003", "authors": "Lamark T, Perander M, Outzen H, Kristiansen K, Overvatn A, Michaelsen E, Bjorkoy G, Johansen T", "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" } ], "reference": [ { "type": "PubMed", "id": "12813044", "url": "https://glygen.org/publication/PubMed/12813044" } ] } ], "crossref": [ { "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "12813044", "url": "https://glygen.org/publication/PubMed/12813044", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "E", "start_aa": "E", "up_seq": "PFTMKWIDEEGDPCTVSSQL", "down_seq": "LEEAFRLYELNKDSELLIHV", "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Loss of interaction with SQSTM1.", "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" }, { "database": "PubMed", "id": "12813044", "url": "https://glygen.org/publication/PubMed/12813044" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "541", "end_pos": "541" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "27", "end_pos": "27" }, { "start_pos": "28", "end_pos": "28" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "70", "end_pos": "70" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "76", "end_pos": "76" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "85", "end_pos": "85" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "264", "end_pos": "264" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "333", "end_pos": "333" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "563", "end_pos": "563" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "Q62074-1.70.70", "categories": [ "mutagenesis_flag" ] }, { "distance": 13, "direction": "downstream", "id": "Q62074-1.72.72", "categories": [ "mutagenesis_flag" ] }, { "distance": 11, "direction": "downstream", "id": "Q62074-1.74.74", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "downstream", "id": "Q62074-1.76.76", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q62074-1.83.83", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q62074-1.264.264", "start_pos": 264, "end_pos": 264, "uniprot_canonical_ac": "Q62074-1", "length": 595, "uniprot_id": "KPCI_MOUSE", "protein_name": "Protein kinase C iota type", "refseq_ac": "NP_032883", "refseq_name": "protein kinase C iota type isoform 1", "gene_name": "Prkci", "gene_names_uniprotkb": "Prkci; Pkcl", "gene_names_refseq": "2310021H13Rik; PKClambda; Pkci; Pkcl; Prkci; Prkcl; aPKClambda; mKIAA4165", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "ASSSLGLQDFDLLRVIGRGS", "down_seq": "AKVLLVRLKKTDRIYAMKVV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by SRC", "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" } ], "site_lbl": "Tyr264" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "541", "end_pos": "541" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "27", "end_pos": "27" }, { "start_pos": "28", "end_pos": "28" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "70", "end_pos": "70" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "76", "end_pos": "76" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "85", "end_pos": "85" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "264", "end_pos": "264" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "333", "end_pos": "333" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "563", "end_pos": "563" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "upstream", "id": "Q62074-1.279.279", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q62074-1.279.279", "start_pos": 279, "end_pos": 279, "uniprot_canonical_ac": "Q62074-1", "length": 595, "uniprot_id": "KPCI_MOUSE", "protein_name": "Protein kinase C iota type", "refseq_ac": "NP_032883", "refseq_name": "protein kinase C iota type isoform 1", "gene_name": "Prkci", "gene_names_uniprotkb": "Prkci; Pkcl", "gene_names_refseq": "2310021H13Rik; PKClambda; Pkci; Pkcl; Prkci; Prkcl; aPKClambda; mKIAA4165", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "IGRGSYAKVLLVRLKKTDRI", "down_seq": "AMKVVKKELVNDDEDIDWVQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by SRC", "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" } ], "site_lbl": "Tyr279" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "541", "end_pos": "541" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "27", "end_pos": "27" }, { "start_pos": "28", "end_pos": "28" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "70", "end_pos": "70" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "76", "end_pos": "76" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "85", "end_pos": "85" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "264", "end_pos": "264" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "333", "end_pos": "333" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "563", "end_pos": "563" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "Q62074-1.264.264", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q62074-1.333.333", "start_pos": 333, "end_pos": 333, "uniprot_canonical_ac": "Q62074-1", "length": 595, "uniprot_id": "KPCI_MOUSE", "protein_name": "Protein kinase C iota type", "refseq_ac": "NP_032883", "refseq_name": "protein kinase C iota type isoform 1", "gene_name": "Prkci", "gene_names_uniprotkb": "Prkci; Pkcl", "gene_names_refseq": "2310021H13Rik; PKClambda; Pkci; Pkcl; Prkci; Prkcl; aPKClambda; mKIAA4165", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "FLVGLHSCFQTESRLFFVIE", "down_seq": "VNGGDLMFHMQRQRKLPEEH", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by SRC", "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" } ], "site_lbl": "Tyr333" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "541", "end_pos": "541" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "27", "end_pos": "27" }, { "start_pos": "28", "end_pos": "28" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "70", "end_pos": "70" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "76", "end_pos": "76" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "85", "end_pos": "85" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "264", "end_pos": "264" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "333", "end_pos": "333" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "563", "end_pos": "563" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q62074-1.3.3", "start_pos": 3, "end_pos": 3, "uniprot_canonical_ac": "Q62074-1", "length": 595, "uniprot_id": "KPCI_MOUSE", "protein_name": "Protein kinase C iota type", "refseq_ac": "NP_032883", "refseq_name": "protein kinase C iota type isoform 1", "gene_name": "Prkci", "gene_names_uniprotkb": "Prkci; Pkcl", "gene_names_refseq": "2310021H13Rik; PKClambda; Pkci; Pkcl; Prkci; Prkcl; aPKClambda; mKIAA4165", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "MP", "down_seq": "QRDSSTMSHTVACGGGGDHS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" } ], "site_lbl": "Thr3" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "541", "end_pos": "541" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "27", "end_pos": "27" }, { "start_pos": "28", "end_pos": "28" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "70", "end_pos": "70" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "76", "end_pos": "76" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "85", "end_pos": "85" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "264", "end_pos": "264" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "333", "end_pos": "333" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "563", "end_pos": "563" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "Q62074-1.0.0", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q62074-1.7.7", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q62074-1.8.8", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q62074-1.9.9", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q62074-1.411.411", "start_pos": 411, "end_pos": 411, "uniprot_canonical_ac": "Q62074-1", "length": 595, "uniprot_id": "KPCI_MOUSE", "protein_name": "Protein kinase C iota type", "refseq_ac": "NP_032883", "refseq_name": "protein kinase C iota type isoform 1", "gene_name": "Prkci", "gene_names_uniprotkb": "Prkci; Pkcl", "gene_names_refseq": "2310021H13Rik; PKClambda; Pkci; Pkcl; Prkci; Prkcl; aPKClambda; mKIAA4165", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" }, { "database": "iPTMnet", "id": "Q62074", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q62074" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] } ], "crossref": [ { "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q62074", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q62074", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "IKLTDYGMCKEGLRPGDTTS", "down_seq": "FCGTPNYIAPEILRGEDYGF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" }, { "database": "iPTMnet", "id": "Q62074", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q62074" } ], "site_lbl": "Thr411" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "541", "end_pos": "541" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "27", "end_pos": "27" }, { "start_pos": "28", "end_pos": "28" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "70", "end_pos": "70" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "76", "end_pos": "76" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "85", "end_pos": "85" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "264", "end_pos": "264" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "333", "end_pos": "333" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "563", "end_pos": "563" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q62074-1.563.563", "start_pos": 563, "end_pos": 563, "uniprot_canonical_ac": "Q62074-1", "length": 595, "uniprot_id": "KPCI_MOUSE", "protein_name": "Protein kinase C iota type", "refseq_ac": "NP_032883", "refseq_name": "protein kinase C iota type isoform 1", "gene_name": "Prkci", "gene_names_uniprotkb": "Prkci; Pkcl", "gene_names_refseq": "2310021H13Rik; PKClambda; Pkci; Pkcl; Prkci; Prkcl; aPKClambda; mKIAA4165", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" }, { "database": "iPTMnet", "id": "Q62074", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q62074" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "title": "Substrate recognition mechanism of atypical protein kinase Cs revealed by the structure of PKCiota in complex with a substrate peptide from Par-3.", "journal": "Structure (London, England : 1993)", "date": "2012", "authors": "Wang C, Shang Y, Yu J, Zhang M", "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" }, { "database": "iPTMnet", "id": "Q62074", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q62074" } ], "reference": [ { "type": "PubMed", "id": "22579248", "url": "https://glygen.org/publication/PubMed/22579248" } ] } ], "crossref": [ { "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22579248", "url": "https://glygen.org/publication/PubMed/22579248", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q62074", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q62074", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "SGEFGLDNFDSQFTNEPVQL", "down_seq": "PDDDDIVRKIDQSEFEGFEY", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "PubMed", "id": "22579248", "url": "https://glygen.org/publication/PubMed/22579248" }, { "database": "iPTMnet", "id": "Q62074", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q62074" } ], "site_lbl": "Thr563" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "541", "end_pos": "541" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "27", "end_pos": "27" }, { "start_pos": "28", "end_pos": "28" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "70", "end_pos": "70" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "76", "end_pos": "76" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "85", "end_pos": "85" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "264", "end_pos": "264" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "333", "end_pos": "333" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "563", "end_pos": "563" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q62074-1.7.7", "start_pos": 7, "end_pos": 7, "uniprot_canonical_ac": "Q62074-1", "length": 595, "uniprot_id": "KPCI_MOUSE", "protein_name": "Protein kinase C iota type", "refseq_ac": "NP_032883", "refseq_name": "protein kinase C iota type isoform 1", "gene_name": "Prkci", "gene_names_uniprotkb": "Prkci; Pkcl", "gene_names_refseq": "2310021H13Rik; PKClambda; Pkci; Pkcl; Prkci; Prkcl; aPKClambda; mKIAA4165", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MPTQRD", "down_seq": "STMSHTVACGGGGDHSHQVR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" } ], "site_lbl": "Ser7" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "541", "end_pos": "541" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "27", "end_pos": "27" }, { "start_pos": "28", "end_pos": "28" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "70", "end_pos": "70" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "76", "end_pos": "76" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "85", "end_pos": "85" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "264", "end_pos": "264" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "333", "end_pos": "333" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "563", "end_pos": "563" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "Q62074-1.0.0", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q62074-1.3.3", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q62074-1.8.8", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q62074-1.9.9", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "Q62074-1.27.27", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q62074-1.8.8", "start_pos": 8, "end_pos": 8, "uniprot_canonical_ac": "Q62074-1", "length": 595, "uniprot_id": "KPCI_MOUSE", "protein_name": "Protein kinase C iota type", "refseq_ac": "NP_032883", "refseq_name": "protein kinase C iota type isoform 1", "gene_name": "Prkci", "gene_names_uniprotkb": "Prkci; Pkcl", "gene_names_refseq": "2310021H13Rik; PKClambda; Pkci; Pkcl; Prkci; Prkcl; aPKClambda; mKIAA4165", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MPTQRDS", "down_seq": "TMSHTVACGGGGDHSHQVRV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" } ], "site_lbl": "Ser8" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "541", "end_pos": "541" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "27", "end_pos": "27" }, { "start_pos": "28", "end_pos": "28" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "70", "end_pos": "70" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "76", "end_pos": "76" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "85", "end_pos": "85" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "264", "end_pos": "264" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "333", "end_pos": "333" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "563", "end_pos": "563" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "Q62074-1.0.0", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q62074-1.3.3", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q62074-1.7.7", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q62074-1.9.9", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q62074-1.27.27", "categories": [ "mutagenesis_flag" ] }, { "distance": 20, "direction": "upstream", "id": "Q62074-1.28.28", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q62074-1.9.9", "start_pos": 9, "end_pos": 9, "uniprot_canonical_ac": "Q62074-1", "length": 595, "uniprot_id": "KPCI_MOUSE", "protein_name": "Protein kinase C iota type", "refseq_ac": "NP_032883", "refseq_name": "protein kinase C iota type isoform 1", "gene_name": "Prkci", "gene_names_uniprotkb": "Prkci; Pkcl", "gene_names_refseq": "2310021H13Rik; PKClambda; Pkci; Pkcl; Prkci; Prkcl; aPKClambda; mKIAA4165", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "MPTQRDSS", "down_seq": "MSHTVACGGGGDHSHQVRVK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q62074", "url": "https://www.uniprot.org/uniprotkb/Q62074" } ], "site_lbl": "Thr9" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "541", "end_pos": "541" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "27", "end_pos": "27" }, { "start_pos": "28", "end_pos": "28" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "70", "end_pos": "70" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "76", "end_pos": "76" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "85", "end_pos": "85" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "264", "end_pos": "264" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "333", "end_pos": "333" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "563", "end_pos": "563" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "Q62074-1.0.0", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q62074-1.3.3", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q62074-1.7.7", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q62074-1.8.8", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q62074-1.27.27", "categories": [ "mutagenesis_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q62074-1.28.28", "categories": [ "mutagenesis_flag" ] }, { "distance": 20, "direction": "upstream", "id": "Q62074-1.29.29", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P18653-1.723.723", "start_pos": 723, "end_pos": 723, "uniprot_canonical_ac": "P18653-1", "length": 724, "uniprot_id": "KS6A1_MOUSE", "protein_name": "Ribosomal protein S6 kinase alpha-1", "refseq_ac": "NP_001272434", "refseq_name": "ribosomal protein S6 kinase alpha-1 isoform b", "gene_name": "Rps6ka1", "gene_names_uniprotkb": "Rps6ka1; Mapkapk1a; Rsk1", "gene_names_refseq": "Mapkapk-1a; Rps6ka1; Rsk-1; Rsk1; Rsk; S6K-alpha-1; p90-Rsk1; p90Rsk1; p90S6K; p90rsk", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P18653", "url": "https://www.uniprot.org/uniprotkb/P18653" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Age-related loss of neural stem cell O-GlcNAc promotes a glial fate switch through STAT3 activation.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2020", "authors": "White CW 3rd, Fan X, Maynard JC, Wheatley EG, Bieri G, Couthouis J, Burlingame AL, Villeda SA", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "P18653", "url": "https://oglcnac.org/atlas/detail/P18653" } ], "reference": [ { "type": "PubMed", "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054" } ] } ], "crossref": [ { "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P18653", "url": "https://oglcnac.org/atlas/detail/P18653", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "LKPIESSILAQRRVRKLPST", "down_seq": "", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr723", "evidence": [ { "id": "32848054", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32848054" }, { "id": "P18653", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P18653" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "723", "end_pos": "723" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "221", "end_pos": "221" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "348", "end_pos": "348" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "562", "end_pos": "562" }, { "start_pos": "721", "end_pos": "721" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P18653-1.721.721", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P18653-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "P18653-1", "length": 724, "uniprot_id": "KS6A1_MOUSE", "protein_name": "Ribosomal protein S6 kinase alpha-1", "refseq_ac": "NP_001272434", "refseq_name": "ribosomal protein S6 kinase alpha-1 isoform b", "gene_name": "Rps6ka1", "gene_names_uniprotkb": "Rps6ka1; Mapkapk1a; Rsk1", "gene_names_refseq": "Mapkapk-1a; Rps6ka1; Rsk-1; Rsk1; Rsk; S6K-alpha-1; p90-Rsk1; p90Rsk1; p90S6K; p90rsk", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P18653", "url": "https://www.uniprot.org/uniprotkb/P18653" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "The New Chemical Reporter 6-Alkynyl-6-deoxy-GlcNAc Reveals O-GlcNAc Modification of the Apoptotic Caspases That Can Block the Cleavage/Activation of Caspase-8.", "journal": "Journal of the American Chemical Society", "date": "2017", "authors": "Chuh KN, Batt AR, Zaro BW, Darabedian N, Marotta NP, Brennan CK, Amirhekmat A, Pratt MR", "evidence": [ { "database": "O-GlcNAc Database", "id": "P18653", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P18653" } ], "reference": [ { "type": "PubMed", "id": "28528544", "url": "https://glygen.org/publication/PubMed/28528544" } ] }, { "title": "Novel Antibodies for the Simple and Efficient Enrichment of Native O-GlcNAc Modified Peptides.", "journal": "Molecular & cellular proteomics : MCP", "date": "2021", "authors": "Burt RA, Dejanovic B, Peckham HJ, Lee KA, Li X, Ounadjela JR, Rao A, Malaker SA, Carr SA, Myers SA", "evidence": [ { "database": "O-GlcNAc Database", "id": "P18653", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P18653" } ], "reference": [ { "type": "PubMed", "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516" } ] }, { "title": "Dynamic O-GlcNAcylation governs long-range chromatin interactions in V(D)J recombination during early B-cell development.", "journal": "Cellular & molecular immunology", "date": "2025-01", "authors": "Jeon Bong Chan, Kim Yu-Ji, Park Ae Kyung, Song Mi-Ran, Na Ki Myeong, Lee Juwon, An Dasom, Park Yeseul, Hwang Heeyoun, Kim Tae-Don, Lim Junghyun, Park Sung-Kyun", "evidence": [ { "database": "O-GlcNAc Database", "id": "P18653", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P18653" } ], "reference": [ { "type": "PubMed", "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609" } ] } ], "crossref": [ { "id": "28528544", "url": "https://glygen.org/publication/PubMed/28528544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P18653", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P18653", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516", "database": "PubMed", "categories": [ "Other" ] }, { "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609", "database": "PubMed", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "28528544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/28528544" }, { "id": "P18653", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P18653" }, { "id": "34678516", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34678516" }, { "id": "39627609", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39627609" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "723", "end_pos": "723" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "221", "end_pos": "221" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "348", "end_pos": "348" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "562", "end_pos": "562" }, { "start_pos": "721", "end_pos": "721" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P18653-1.221.221", "start_pos": 221, "end_pos": 221, "uniprot_canonical_ac": "P18653-1", "length": 724, "uniprot_id": "KS6A1_MOUSE", "protein_name": "Ribosomal protein S6 kinase alpha-1", "refseq_ac": "NP_001272434", "refseq_name": "ribosomal protein S6 kinase alpha-1 isoform b", "gene_name": "Rps6ka1", "gene_names_uniprotkb": "Rps6ka1; Mapkapk1a; Rsk1", "gene_names_refseq": "Mapkapk-1a; Rps6ka1; Rsk-1; Rsk1; Rsk; S6K-alpha-1; p90-Rsk1; p90Rsk1; p90S6K; p90rsk", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P18653", "url": "https://www.uniprot.org/uniprotkb/P18653" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Increased 90-kDa ribosomal S6 kinase (Rsk) activity is protective against mutant huntingtin toxicity.", "journal": "Molecular neurodegeneration", "date": "2011", "authors": "Xifro X, Anglada-Huguet M, Rue L, Saavedra A, Perez-Navarro E, Alberch J", "evidence": [ { "database": "iPTMnet", "id": "P18653", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18653" } ], "reference": [ { "type": "PubMed", "id": "22041125", "url": "https://glygen.org/publication/PubMed/22041125" } ] } ], "crossref": [ { "id": "P18653", "url": "https://www.uniprot.org/uniprotkb/P18653", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P18653", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18653", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "22041125", "url": "https://glygen.org/publication/PubMed/22041125", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "IKLTDFGLSKEAIDHEKKAY", "down_seq": "FCGTVEYMAPEVVNRQGHTH", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by PDPK1", "evidence": [ { "database": "UniProtKB", "id": "P18653", "url": "https://www.uniprot.org/uniprotkb/P18653" }, { "database": "iPTMnet", "id": "P18653", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18653" }, { "database": "PubMed", "id": "22041125", "url": "https://glygen.org/publication/PubMed/22041125" } ], "site_lbl": "Ser221" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "723", "end_pos": "723" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "221", "end_pos": "221" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "348", "end_pos": "348" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "562", "end_pos": "562" }, { "start_pos": "721", "end_pos": "721" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P18653-1.296.296", "start_pos": 296, "end_pos": 296, "uniprot_canonical_ac": "P18653-1", "length": 724, "uniprot_id": "KS6A1_MOUSE", "protein_name": "Ribosomal protein S6 kinase alpha-1", "refseq_ac": "NP_001272434", "refseq_name": "ribosomal protein S6 kinase alpha-1 isoform b", "gene_name": "Rps6ka1", "gene_names_uniprotkb": "Rps6ka1; Mapkapk1a; Rsk1", "gene_names_refseq": "Mapkapk-1a; Rps6ka1; Rsk-1; Rsk1; Rsk; S6K-alpha-1; p90-Rsk1; p90Rsk1; p90S6K; p90rsk", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P18653", "url": "https://www.uniprot.org/uniprotkb/P18653" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P18653", "url": "https://www.uniprot.org/uniprotkb/P18653", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TEAQSLLRALFKRNPANRLG", "down_seq": "GPDGAEEIKRHIFYSTIDWN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P18653", "url": "https://www.uniprot.org/uniprotkb/P18653" } ], "site_lbl": "Ser296" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "723", "end_pos": "723" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "221", "end_pos": "221" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "348", "end_pos": "348" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "562", "end_pos": "562" }, { "start_pos": "721", "end_pos": "721" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P18653-1.348.348", "start_pos": 348, "end_pos": 348, "uniprot_canonical_ac": "P18653-1", "length": 724, "uniprot_id": "KS6A1_MOUSE", "protein_name": "Ribosomal protein S6 kinase alpha-1", "refseq_ac": "NP_001272434", "refseq_name": "ribosomal protein S6 kinase alpha-1 isoform b", "gene_name": "Rps6ka1", "gene_names_uniprotkb": "Rps6ka1; Mapkapk1a; Rsk1", "gene_names_refseq": "Mapkapk-1a; Rps6ka1; Rsk-1; Rsk1; Rsk; S6K-alpha-1; p90-Rsk1; p90Rsk1; p90S6K; p90rsk", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P18653", "url": "https://www.uniprot.org/uniprotkb/P18653" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P18653", "url": "https://www.uniprot.org/uniprotkb/P18653", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "KPAVAQPDDTFYFDTEFTSR", "down_seq": "PRDSPGIPPSAGAHQLFRGF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P18653", "url": "https://www.uniprot.org/uniprotkb/P18653" } ], "site_lbl": "Thr348" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "723", "end_pos": "723" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "221", "end_pos": "221" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "348", "end_pos": "348" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "562", "end_pos": "562" }, { "start_pos": "721", "end_pos": "721" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "P18653-1.352.352", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P18653-1.358.358", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P18653-1.352.352", "start_pos": 352, "end_pos": 352, "uniprot_canonical_ac": "P18653-1", "length": 724, "uniprot_id": "KS6A1_MOUSE", "protein_name": "Ribosomal protein S6 kinase alpha-1", "refseq_ac": "NP_001272434", "refseq_name": "ribosomal protein S6 kinase alpha-1 isoform b", "gene_name": "Rps6ka1", "gene_names_uniprotkb": "Rps6ka1; Mapkapk1a; Rsk1", "gene_names_refseq": "Mapkapk-1a; Rps6ka1; Rsk-1; Rsk1; Rsk; S6K-alpha-1; p90-Rsk1; p90Rsk1; p90S6K; p90rsk", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P18653", "url": "https://www.uniprot.org/uniprotkb/P18653" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P18653", "url": "https://www.uniprot.org/uniprotkb/P18653", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AQPDDTFYFDTEFTSRTPRD", "down_seq": "PGIPPSAGAHQLFRGFSFVA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P18653", "url": "https://www.uniprot.org/uniprotkb/P18653" } ], "site_lbl": "Ser352" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "723", "end_pos": "723" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "221", "end_pos": "221" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "348", "end_pos": "348" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "562", "end_pos": "562" }, { "start_pos": "721", "end_pos": "721" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "P18653-1.348.348", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P18653-1.358.358", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P18653-1.369.369", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P18653-1.358.358", "start_pos": 358, "end_pos": 358, "uniprot_canonical_ac": "P18653-1", "length": 724, "uniprot_id": "KS6A1_MOUSE", "protein_name": "Ribosomal protein S6 kinase alpha-1", "refseq_ac": "NP_001272434", "refseq_name": "ribosomal protein S6 kinase alpha-1 isoform b", "gene_name": "Rps6ka1", "gene_names_uniprotkb": "Rps6ka1; Mapkapk1a; Rsk1", "gene_names_refseq": "Mapkapk-1a; Rps6ka1; Rsk-1; Rsk1; Rsk; S6K-alpha-1; p90-Rsk1; p90Rsk1; p90S6K; p90rsk", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P18653", "url": "https://www.uniprot.org/uniprotkb/P18653" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P18653", "url": "https://www.uniprot.org/uniprotkb/P18653", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "FYFDTEFTSRTPRDSPGIPP", "down_seq": "AGAHQLFRGFSFVATGLMED", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P18653", "url": "https://www.uniprot.org/uniprotkb/P18653" } ], "site_lbl": "Ser358" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "723", "end_pos": "723" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "221", "end_pos": "221" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "348", "end_pos": "348" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "562", "end_pos": "562" }, { "start_pos": "721", "end_pos": "721" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "P18653-1.348.348", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P18653-1.352.352", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P18653-1.369.369", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P18653-1.369.369", "start_pos": 369, "end_pos": 369, "uniprot_canonical_ac": "P18653-1", "length": 724, "uniprot_id": "KS6A1_MOUSE", "protein_name": "Ribosomal protein S6 kinase alpha-1", "refseq_ac": "NP_001272434", "refseq_name": "ribosomal protein S6 kinase alpha-1 isoform b", "gene_name": "Rps6ka1", "gene_names_uniprotkb": "Rps6ka1; Mapkapk1a; Rsk1", "gene_names_refseq": "Mapkapk-1a; Rps6ka1; Rsk-1; Rsk1; Rsk; S6K-alpha-1; p90-Rsk1; p90Rsk1; p90S6K; p90rsk", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P18653", "url": "https://www.uniprot.org/uniprotkb/P18653" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P18653", "url": "https://www.uniprot.org/uniprotkb/P18653" }, { "database": "iPTMnet", "id": "P18653", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18653" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] }, { "title": "The phagosomal proteome in interferon-gamma-activated macrophages.", "journal": "Immunity", "date": "2009", "authors": "Trost M, English L, Lemieux S, Courcelles M, Desjardins M, Thibault P", "evidence": [ { "database": "UniProtKB", "id": "P18653", "url": "https://www.uniprot.org/uniprotkb/P18653" }, { "database": "iPTMnet", "id": "P18653", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18653" } ], "reference": [ { "type": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" } ] }, { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P18653", "url": "https://www.uniprot.org/uniprotkb/P18653" }, { "database": "iPTMnet", "id": "P18653", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18653" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "P18653", "url": "https://www.uniprot.org/uniprotkb/P18653", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P18653", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18653", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PRDSPGIPPSAGAHQLFRGF", "down_seq": "FVATGLMEDDGKPRTTQAPL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P18653", "url": "https://www.uniprot.org/uniprotkb/P18653" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" }, { "database": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "P18653", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18653" } ], "site_lbl": "Ser369" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "723", "end_pos": "723" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "221", "end_pos": "221" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "348", "end_pos": "348" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "562", "end_pos": "562" }, { "start_pos": "721", "end_pos": "721" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P18653-1.352.352", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P18653-1.358.358", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P18653-1.54.54", "start_pos": 54, "end_pos": 54, "uniprot_canonical_ac": "P18653-1", "length": 724, "uniprot_id": "KS6A1_MOUSE", "protein_name": "Ribosomal protein S6 kinase alpha-1", "refseq_ac": "NP_001272434", "refseq_name": "ribosomal protein S6 kinase alpha-1 isoform b", "gene_name": "Rps6ka1", "gene_names_uniprotkb": "Rps6ka1; Mapkapk1a; Rsk1", "gene_names_refseq": "Mapkapk-1a; Rps6ka1; Rsk-1; Rsk1; Rsk; S6K-alpha-1; p90-Rsk1; p90Rsk1; p90S6K; p90rsk", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P18653", "url": "https://www.uniprot.org/uniprotkb/P18653" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P18653", "url": "https://www.uniprot.org/uniprotkb/P18653", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PSKDEAILKEISITHHVKAG", "down_seq": "EKADPSQFELLKVLGQGSFG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P18653", "url": "https://www.uniprot.org/uniprotkb/P18653" } ], "site_lbl": "Ser54" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "723", "end_pos": "723" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "221", "end_pos": "221" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "348", "end_pos": "348" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "562", "end_pos": "562" }, { "start_pos": "721", "end_pos": "721" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P18653-1.562.562", "start_pos": 562, "end_pos": 562, "uniprot_canonical_ac": "P18653-1", "length": 724, "uniprot_id": "KS6A1_MOUSE", "protein_name": "Ribosomal protein S6 kinase alpha-1", "refseq_ac": "NP_001272434", "refseq_name": "ribosomal protein S6 kinase alpha-1 isoform b", "gene_name": "Rps6ka1", "gene_names_uniprotkb": "Rps6ka1; Mapkapk1a; Rsk1", "gene_names_refseq": "Mapkapk-1a; Rps6ka1; Rsk-1; Rsk1; Rsk; S6K-alpha-1; p90-Rsk1; p90Rsk1; p90S6K; p90rsk", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P18653", "url": "https://www.uniprot.org/uniprotkb/P18653" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P18653", "url": "https://www.uniprot.org/uniprotkb/P18653", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "LRICDFGFAKQLRAENGLLM", "down_seq": "PCYTANFVAPEVLKRQGYDE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P18653", "url": "https://www.uniprot.org/uniprotkb/P18653" } ], "site_lbl": "Thr562" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "723", "end_pos": "723" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "221", "end_pos": "221" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "348", "end_pos": "348" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "562", "end_pos": "562" }, { "start_pos": "721", "end_pos": "721" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P18653-1.721.721", "start_pos": 721, "end_pos": 721, "uniprot_canonical_ac": "P18653-1", "length": 724, "uniprot_id": "KS6A1_MOUSE", "protein_name": "Ribosomal protein S6 kinase alpha-1", "refseq_ac": "NP_001272434", "refseq_name": "ribosomal protein S6 kinase alpha-1 isoform b", "gene_name": "Rps6ka1", "gene_names_uniprotkb": "Rps6ka1; Mapkapk1a; Rsk1", "gene_names_refseq": "Mapkapk-1a; Rps6ka1; Rsk-1; Rsk1; Rsk; S6K-alpha-1; p90-Rsk1; p90Rsk1; p90S6K; p90rsk", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P18653", "url": "https://www.uniprot.org/uniprotkb/P18653" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P18653", "url": "https://www.uniprot.org/uniprotkb/P18653", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PQLKPIESSILAQRRVRKLP", "down_seq": "TTL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P18653", "url": "https://www.uniprot.org/uniprotkb/P18653" } ], "site_lbl": "Ser721" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "723", "end_pos": "723" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "221", "end_pos": "221" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "348", "end_pos": "348" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "562", "end_pos": "562" }, { "start_pos": "721", "end_pos": "721" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P18653-1.723.723", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O35671-1.38.38", "start_pos": 38, "end_pos": 38, "uniprot_canonical_ac": "O35671-1", "length": 200, "uniprot_id": "ITBP1_MOUSE", "protein_name": "Integrin beta-1-binding protein 1", "refseq_ac": "NP_032429", "refseq_name": "integrin beta-1-binding protein 1", "gene_name": "Itgb1bp1", "gene_names_uniprotkb": "Itgb1bp1", "gene_names_refseq": "Icap1; Itgb1bp1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O35671", "url": "https://www.uniprot.org/uniprotkb/O35671" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "O35671", "url": "https://www.uniprot.org/uniprotkb/O35671", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "EISTKSKSVDSSLGGLSRSS", "down_seq": "VASLDTDSTKSSGQSNSNLD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine; by CaMK2", "evidence": [ { "database": "UniProtKB", "id": "O35671", "url": "https://www.uniprot.org/uniprotkb/O35671" } ], "site_lbl": "Thr38" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "38", "end_pos": "38" }, { "start_pos": "41", "end_pos": "41" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "O35671-1.41.41", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O35671-1.41.41", "start_pos": 41, "end_pos": 41, "uniprot_canonical_ac": "O35671-1", "length": 200, "uniprot_id": "ITBP1_MOUSE", "protein_name": "Integrin beta-1-binding protein 1", "refseq_ac": "NP_032429", "refseq_name": "integrin beta-1-binding protein 1", "gene_name": "Itgb1bp1", "gene_names_uniprotkb": "Itgb1bp1", "gene_names_refseq": "Icap1; Itgb1bp1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O35671", "url": "https://www.uniprot.org/uniprotkb/O35671" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "O35671", "url": "https://www.uniprot.org/uniprotkb/O35671" }, { "database": "iPTMnet", "id": "O35671", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O35671" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "O35671", "url": "https://www.uniprot.org/uniprotkb/O35671", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "O35671", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O35671", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TKSKSVDSSLGGLSRSSTVA", "down_seq": "LDTDSTKSSGQSNSNLDTCA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O35671", "url": "https://www.uniprot.org/uniprotkb/O35671" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "O35671", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O35671" } ], "site_lbl": "Ser41" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "38", "end_pos": "38" }, { "start_pos": "41", "end_pos": "41" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "O35671-1.38.38", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q148V7-1.169.169", "start_pos": 169, "end_pos": 169, "uniprot_canonical_ac": "Q148V7-1", "length": 1216, "uniprot_id": "RELCH_MOUSE", "protein_name": "RAB11-binding protein RELCH", "refseq_ac": "NP_083625", "refseq_name": "RAB11-binding protein RELCH isoform 2", "gene_name": "Relch", "gene_names_uniprotkb": "Relch; 2310035C23Rik; Kiaa1468", "gene_names_refseq": "2310035C23Rik; 6430401N10; Kiaa1468; Relch; mKIAA1468", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases.", "journal": "Frontiers in aging", "date": "2021", "authors": "Huynh Van N, Wang Sheng, Ouyang Xiaosen, Wani Willayat Y, Johnson Michelle S, Chacko Balu K, Jegga Anil G, Qian Wei-Jun, Chatham John C, Darley-Usmar Victor M, Zhang Jianhua", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q148V7", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q148V7" } ], "reference": [ { "type": "PubMed", "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q148V7", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q148V7" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Age-related loss of neural stem cell O-GlcNAc promotes a glial fate switch through STAT3 activation.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2020", "authors": "White CW 3rd, Fan X, Maynard JC, Wheatley EG, Bieri G, Couthouis J, Burlingame AL, Villeda SA", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q148V7", "url": "https://oglcnac.org/atlas/detail/Q148V7" } ], "reference": [ { "type": "PubMed", "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054" } ] } ], "crossref": [ { "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q148V7", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q148V7", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q148V7", "url": "https://oglcnac.org/atlas/detail/Q148V7", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "APGIPGASIVGGAGGREPST", "down_seq": "SGGGQLNRAGSISTLDSLDF", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr169", "evidence": [ { "id": "35822049", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/35822049" }, { "id": "Q148V7", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q148V7" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "32848054", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32848054" }, { "id": "Q148V7", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q148V7" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "169", "end_pos": "169" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "996", "end_pos": "996" } ] }, { "type": "snv", "site_list": [ { "start_pos": "996", "end_pos": "996" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1149", "end_pos": "1149" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "453", "end_pos": "453" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "792", "end_pos": "792" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "upstream", "id": "Q148V7-1.180.180", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q148V7-1.182.182", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q148V7-1.183.183", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "Q148V7-1.186.186", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q148V7-1.224.224", "start_pos": 224, "end_pos": 224, "uniprot_canonical_ac": "Q148V7-1", "length": 1216, "uniprot_id": "RELCH_MOUSE", "protein_name": "RAB11-binding protein RELCH", "refseq_ac": "NP_083625", "refseq_name": "RAB11-binding protein RELCH isoform 2", "gene_name": "Relch", "gene_names_uniprotkb": "Relch; 2310035C23Rik; Kiaa1468", "gene_names_refseq": "2310035C23Rik; 6430401N10; Kiaa1468; Relch; mKIAA1468", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Capturing site-specific heterogeneity with large-scale N-glycoproteome analysis.", "journal": "Nature communications", "date": "2019", "authors": "Riley NM, Hebert AS, Westphall MS, Coon JJ", "evidence": [ { "database": "GlyConnect", "id": "2482", "url": "https://glyconnect.expasy.org/browser/proteins/2482" } ], "reference": [ { "type": "PubMed", "id": "30899004", "url": "https://glygen.org/publication/PubMed/30899004" } ] } ], "crossref": [ { "id": "30899004", "url": "https://glygen.org/publication/PubMed/30899004", "database": "PubMed", "categories": [ "Other" ] }, { "id": "2482", "url": "https://glyconnect.expasy.org/browser/proteins/2482", "database": "GlyConnect", "categories": [ "Glycomics", "Glycoproteomics" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "VAVLEFELRKAKETIQALRA", "down_seq": "LTKAAEHEVPLQERKNYKSS", "glycosylation": [ { "glytoucan_ac": "G74724QE", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn224", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2482", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2482" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "169", "end_pos": "169" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "996", "end_pos": "996" } ] }, { "type": "snv", "site_list": [ { "start_pos": "996", "end_pos": "996" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1149", "end_pos": "1149" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "453", "end_pos": "453" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "792", "end_pos": "792" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q148V7-1.469.469", "start_pos": 469, "end_pos": 469, "uniprot_canonical_ac": "Q148V7-1", "length": 1216, "uniprot_id": "RELCH_MOUSE", "protein_name": "RAB11-binding protein RELCH", "refseq_ac": "NP_083625", "refseq_name": "RAB11-binding protein RELCH isoform 2", "gene_name": "Relch", "gene_names_uniprotkb": "Relch; 2310035C23Rik; Kiaa1468", "gene_names_refseq": "2310035C23Rik; 6430401N10; Kiaa1468; Relch; mKIAA1468", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases.", "journal": "Frontiers in aging", "date": "2021", "authors": "Huynh Van N, Wang Sheng, Ouyang Xiaosen, Wani Willayat Y, Johnson Michelle S, Chacko Balu K, Jegga Anil G, Qian Wei-Jun, Chatham John C, Darley-Usmar Victor M, Zhang Jianhua", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q148V7", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q148V7" } ], "reference": [ { "type": "PubMed", "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q148V7", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q148V7" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Age-related loss of neural stem cell O-GlcNAc promotes a glial fate switch through STAT3 activation.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2020", "authors": "White CW 3rd, Fan X, Maynard JC, Wheatley EG, Bieri G, Couthouis J, Burlingame AL, Villeda SA", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q148V7", "url": "https://oglcnac.org/atlas/detail/Q148V7" } ], "reference": [ { "type": "PubMed", "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054" } ] } ], "crossref": [ { "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q148V7", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q148V7", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q148V7", "url": "https://oglcnac.org/atlas/detail/Q148V7", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PKENSSGSFPRKEREELPPS", "down_seq": "VSNKTTLHFDQPNRKLSPAF", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser469", "evidence": [ { "id": "35822049", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/35822049" }, { "id": "Q148V7", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q148V7" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "32848054", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32848054" }, { "id": "Q148V7", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q148V7" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "169", "end_pos": "169" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "996", "end_pos": "996" } ] }, { "type": "snv", "site_list": [ { "start_pos": "996", "end_pos": "996" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1149", "end_pos": "1149" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "453", "end_pos": "453" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "792", "end_pos": "792" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "Q148V7-1.453.453", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q148V7-1.996.996", "start_pos": 996, "end_pos": 996, "uniprot_canonical_ac": "Q148V7-1", "length": 1216, "uniprot_id": "RELCH_MOUSE", "protein_name": "RAB11-binding protein RELCH", "refseq_ac": "NP_083625", "refseq_name": "RAB11-binding protein RELCH isoform 2", "gene_name": "Relch", "gene_names_uniprotkb": "Relch; 2310035C23Rik; Kiaa1468", "gene_names_refseq": "2310035C23Rik; 6430401N10; Kiaa1468; Relch; mKIAA1468", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "rs3388494313", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388494313", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "TSALVRCTAARMFELLVKGV", "down_seq": "ETLVAQRVVPALITLSSDPE", "glycosylation": [ { "glytoucan_ac": "G41071NU", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "GVNETLVAQRVVPALITLSSDPEISVRIATIPAFGTIMETVIQR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn996", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "snv": [ { "evidence": [ { "id": "rs3388494313", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388494313" } ], "glycoeffect": [ "n-glyco-sequon-loss" ], "sequence_org": "N", "sequence_mut": "Y", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-loss (NET->YET).", "chr_id": "1", "chr_pos": "105668178", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "N996", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "169", "end_pos": "169" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "996", "end_pos": "996" } ] }, { "type": "snv", "site_list": [ { "start_pos": "996", "end_pos": "996" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1149", "end_pos": "1149" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "453", "end_pos": "453" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "792", "end_pos": "792" } ] } ], "categories": [ "glycosylation_flag", "snv_flag" ], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q148V7-1.1149.1149", "start_pos": 1149, "end_pos": 1149, "uniprot_canonical_ac": "Q148V7-1", "length": 1216, "uniprot_id": "RELCH_MOUSE", "protein_name": "RAB11-binding protein RELCH", "refseq_ac": "NP_083625", "refseq_name": "RAB11-binding protein RELCH isoform 2", "gene_name": "Relch", "gene_names_uniprotkb": "Relch; 2310035C23Rik; Kiaa1468", "gene_names_refseq": "2310035C23Rik; 6430401N10; Kiaa1468; Relch; mKIAA1468", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7" }, { "database": "iPTMnet", "id": "Q148V7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q148V7" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q148V7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q148V7", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LMVNHFLPGLRCLRTDMEHL", "down_seq": "PEHEVILSSMIKECEQKVEN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q148V7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q148V7" } ], "site_lbl": "Ser1149" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "169", "end_pos": "169" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "996", "end_pos": "996" } ] }, { "type": "snv", "site_list": [ { "start_pos": "996", "end_pos": "996" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1149", "end_pos": "1149" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "453", "end_pos": "453" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "792", "end_pos": "792" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q148V7-1.180.180", "start_pos": 180, "end_pos": 180, "uniprot_canonical_ac": "Q148V7-1", "length": 1216, "uniprot_id": "RELCH_MOUSE", "protein_name": "RAB11-binding protein RELCH", "refseq_ac": "NP_083625", "refseq_name": "RAB11-binding protein RELCH isoform 2", "gene_name": "Relch", "gene_names_uniprotkb": "Relch; 2310035C23Rik; Kiaa1468", "gene_names_refseq": "2310035C23Rik; 6430401N10; Kiaa1468; Relch; mKIAA1468", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7" }, { "database": "iPTMnet", "id": "Q148V7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q148V7" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7" }, { "database": "iPTMnet", "id": "Q148V7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q148V7" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] } ], "crossref": [ { "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q148V7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q148V7", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GAGGREPSTTSGGGQLNRAG", "down_seq": "ISTLDSLDFARYSDDGNRET", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" }, { "database": "iPTMnet", "id": "Q148V7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q148V7" } ], "site_lbl": "Ser180" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "169", "end_pos": "169" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "996", "end_pos": "996" } ] }, { "type": "snv", "site_list": [ { "start_pos": "996", "end_pos": "996" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1149", "end_pos": "1149" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "453", "end_pos": "453" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "792", "end_pos": "792" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "Q148V7-1.169.169", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q148V7-1.182.182", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q148V7-1.183.183", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q148V7-1.186.186", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q148V7-1.182.182", "start_pos": 182, "end_pos": 182, "uniprot_canonical_ac": "Q148V7-1", "length": 1216, "uniprot_id": "RELCH_MOUSE", "protein_name": "RAB11-binding protein RELCH", "refseq_ac": "NP_083625", "refseq_name": "RAB11-binding protein RELCH isoform 2", "gene_name": "Relch", "gene_names_uniprotkb": "Relch; 2310035C23Rik; Kiaa1468", "gene_names_refseq": "2310035C23Rik; 6430401N10; Kiaa1468; Relch; mKIAA1468", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GGREPSTTSGGGQLNRAGSI", "down_seq": "TLDSLDFARYSDDGNRETDE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7" } ], "site_lbl": "Ser182" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "169", "end_pos": "169" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "996", "end_pos": "996" } ] }, { "type": "snv", "site_list": [ { "start_pos": "996", "end_pos": "996" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1149", "end_pos": "1149" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "453", "end_pos": "453" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "792", "end_pos": "792" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "Q148V7-1.169.169", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q148V7-1.180.180", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q148V7-1.183.183", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q148V7-1.186.186", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q148V7-1.183.183", "start_pos": 183, "end_pos": 183, "uniprot_canonical_ac": "Q148V7-1", "length": 1216, "uniprot_id": "RELCH_MOUSE", "protein_name": "RAB11-binding protein RELCH", "refseq_ac": "NP_083625", "refseq_name": "RAB11-binding protein RELCH isoform 2", "gene_name": "Relch", "gene_names_uniprotkb": "Relch; 2310035C23Rik; Kiaa1468", "gene_names_refseq": "2310035C23Rik; 6430401N10; Kiaa1468; Relch; mKIAA1468", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7" }, { "database": "iPTMnet", "id": "Q148V7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q148V7" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q148V7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q148V7", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "GREPSTTSGGGQLNRAGSIS", "down_seq": "LDSLDFARYSDDGNRETDER", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q148V7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q148V7" } ], "site_lbl": "Thr183" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "169", "end_pos": "169" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "996", "end_pos": "996" } ] }, { "type": "snv", "site_list": [ { "start_pos": "996", "end_pos": "996" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1149", "end_pos": "1149" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "453", "end_pos": "453" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "792", "end_pos": "792" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "Q148V7-1.169.169", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q148V7-1.180.180", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q148V7-1.182.182", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q148V7-1.186.186", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q148V7-1.186.186", "start_pos": 186, "end_pos": 186, "uniprot_canonical_ac": "Q148V7-1", "length": 1216, "uniprot_id": "RELCH_MOUSE", "protein_name": "RAB11-binding protein RELCH", "refseq_ac": "NP_083625", "refseq_name": "RAB11-binding protein RELCH isoform 2", "gene_name": "Relch", "gene_names_uniprotkb": "Relch; 2310035C23Rik; Kiaa1468", "gene_names_refseq": "2310035C23Rik; 6430401N10; Kiaa1468; Relch; mKIAA1468", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7" }, { "database": "iPTMnet", "id": "Q148V7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q148V7" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q148V7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q148V7", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PSTTSGGGQLNRAGSISTLD", "down_seq": "LDFARYSDDGNRETDERVAV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q148V7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q148V7" } ], "site_lbl": "Ser186" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "169", "end_pos": "169" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "996", "end_pos": "996" } ] }, { "type": "snv", "site_list": [ { "start_pos": "996", "end_pos": "996" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1149", "end_pos": "1149" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "453", "end_pos": "453" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "792", "end_pos": "792" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "Q148V7-1.169.169", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q148V7-1.180.180", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q148V7-1.182.182", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q148V7-1.183.183", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q148V7-1.20.20", "start_pos": 20, "end_pos": 20, "uniprot_canonical_ac": "Q148V7-1", "length": 1216, "uniprot_id": "RELCH_MOUSE", "protein_name": "RAB11-binding protein RELCH", "refseq_ac": "NP_083625", "refseq_name": "RAB11-binding protein RELCH isoform 2", "gene_name": "Relch", "gene_names_uniprotkb": "Relch; 2310035C23Rik; Kiaa1468", "gene_names_refseq": "2310035C23Rik; 6430401N10; Kiaa1468; Relch; mKIAA1468", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7" }, { "database": "iPTMnet", "id": "Q148V7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q148V7" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] } ], "crossref": [ { "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q148V7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q148V7", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "", "down_seq": "DSDEDDDEVAATEDRRAGLR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" }, { "database": "iPTMnet", "id": "Q148V7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q148V7" } ], "site_lbl": "Ser20" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "169", "end_pos": "169" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "996", "end_pos": "996" } ] }, { "type": "snv", "site_list": [ { "start_pos": "996", "end_pos": "996" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1149", "end_pos": "1149" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "453", "end_pos": "453" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "792", "end_pos": "792" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "Q148V7-1.22.22", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "Q148V7-1.32.32", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q148V7-1.22.22", "start_pos": 22, "end_pos": 22, "uniprot_canonical_ac": "Q148V7-1", "length": 1216, "uniprot_id": "RELCH_MOUSE", "protein_name": "RAB11-binding protein RELCH", "refseq_ac": "NP_083625", "refseq_name": "RAB11-binding protein RELCH isoform 2", "gene_name": "Relch", "gene_names_uniprotkb": "Relch; 2310035C23Rik; Kiaa1468", "gene_names_refseq": "2310035C23Rik; 6430401N10; Kiaa1468; Relch; mKIAA1468", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7" }, { "database": "iPTMnet", "id": "Q148V7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q148V7" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] } ], "crossref": [ { "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q148V7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q148V7", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AAMAPGGGGSGSGVNPFLSD", "down_seq": "DEDDDEVAATEDRRAGLRLG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" }, { "database": "iPTMnet", "id": "Q148V7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q148V7" } ], "site_lbl": "Ser22" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "169", "end_pos": "169" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "996", "end_pos": "996" } ] }, { "type": "snv", "site_list": [ { "start_pos": "996", "end_pos": "996" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1149", "end_pos": "1149" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "453", "end_pos": "453" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "792", "end_pos": "792" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "Q148V7-1.20.20", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q148V7-1.32.32", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q148V7-1.32.32", "start_pos": 32, "end_pos": 32, "uniprot_canonical_ac": "Q148V7-1", "length": 1216, "uniprot_id": "RELCH_MOUSE", "protein_name": "RAB11-binding protein RELCH", "refseq_ac": "NP_083625", "refseq_name": "RAB11-binding protein RELCH isoform 2", "gene_name": "Relch", "gene_names_uniprotkb": "Relch; 2310035C23Rik; Kiaa1468", "gene_names_refseq": "2310035C23Rik; 6430401N10; Kiaa1468; Relch; mKIAA1468", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7" }, { "database": "iPTMnet", "id": "Q148V7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q148V7" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] } ], "crossref": [ { "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q148V7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q148V7", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "GSGVNPFLSDSDEDDDEVAA", "down_seq": "EDRRAGLRLGAGVGLDPGSA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" }, { "database": "iPTMnet", "id": "Q148V7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q148V7" } ], "site_lbl": "Thr32" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "169", "end_pos": "169" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "996", "end_pos": "996" } ] }, { "type": "snv", "site_list": [ { "start_pos": "996", "end_pos": "996" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1149", "end_pos": "1149" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "453", "end_pos": "453" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "792", "end_pos": "792" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "Q148V7-1.20.20", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "Q148V7-1.22.22", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q148V7-1.385.385", "start_pos": 385, "end_pos": 385, "uniprot_canonical_ac": "Q148V7-1", "length": 1216, "uniprot_id": "RELCH_MOUSE", "protein_name": "RAB11-binding protein RELCH", "refseq_ac": "NP_083625", "refseq_name": "RAB11-binding protein RELCH isoform 2", "gene_name": "Relch", "gene_names_uniprotkb": "Relch; 2310035C23Rik; Kiaa1468", "gene_names_refseq": "2310035C23Rik; 6430401N10; Kiaa1468; Relch; mKIAA1468", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7" }, { "database": "iPTMnet", "id": "Q148V7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q148V7" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q148V7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q148V7", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KISLLNNEKWSLMEQIRRLE", "down_seq": "EMDILKAEHFATPAVGDSVQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q148V7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q148V7" } ], "site_lbl": "Ser385" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "169", "end_pos": "169" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "996", "end_pos": "996" } ] }, { "type": "snv", "site_list": [ { "start_pos": "996", "end_pos": "996" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1149", "end_pos": "1149" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "453", "end_pos": "453" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "792", "end_pos": "792" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q148V7-1.453.453", "start_pos": 453, "end_pos": 453, "uniprot_canonical_ac": "Q148V7-1", "length": 1216, "uniprot_id": "RELCH_MOUSE", "protein_name": "RAB11-binding protein RELCH", "refseq_ac": "NP_083625", "refseq_name": "RAB11-binding protein RELCH isoform 2", "gene_name": "Relch", "gene_names_uniprotkb": "Relch; 2310035C23Rik; Kiaa1468", "gene_names_refseq": "2310035C23Rik; 6430401N10; Kiaa1468; Relch; mKIAA1468", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TKDVHLEIPDAADSFIPKEN", "down_seq": "SGSFPRKEREELPPSSVSNK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7" } ], "site_lbl": "Ser453" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "169", "end_pos": "169" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "996", "end_pos": "996" } ] }, { "type": "snv", "site_list": [ { "start_pos": "996", "end_pos": "996" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1149", "end_pos": "1149" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "453", "end_pos": "453" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "792", "end_pos": "792" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "upstream", "id": "Q148V7-1.469.469", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q148V7-1.54.54", "start_pos": 54, "end_pos": 54, "uniprot_canonical_ac": "Q148V7-1", "length": 1216, "uniprot_id": "RELCH_MOUSE", "protein_name": "RAB11-binding protein RELCH", "refseq_ac": "NP_083625", "refseq_name": "RAB11-binding protein RELCH isoform 2", "gene_name": "Relch", "gene_names_uniprotkb": "Relch; 2310035C23Rik; Kiaa1468", "gene_names_refseq": "2310035C23Rik; 6430401N10; Kiaa1468; Relch; mKIAA1468", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DRRAGLRLGAGVGLDPGSAG", "down_seq": "LSPQDPMALGSSARPGLAVE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7" } ], "site_lbl": "Ser54" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "169", "end_pos": "169" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "996", "end_pos": "996" } ] }, { "type": "snv", "site_list": [ { "start_pos": "996", "end_pos": "996" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1149", "end_pos": "1149" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "453", "end_pos": "453" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "792", "end_pos": "792" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "Q148V7-1.56.56", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q148V7-1.56.56", "start_pos": 56, "end_pos": 56, "uniprot_canonical_ac": "Q148V7-1", "length": 1216, "uniprot_id": "RELCH_MOUSE", "protein_name": "RAB11-binding protein RELCH", "refseq_ac": "NP_083625", "refseq_name": "RAB11-binding protein RELCH isoform 2", "gene_name": "Relch", "gene_names_uniprotkb": "Relch; 2310035C23Rik; Kiaa1468", "gene_names_refseq": "2310035C23Rik; 6430401N10; Kiaa1468; Relch; mKIAA1468", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RAGLRLGAGVGLDPGSAGSL", "down_seq": "PQDPMALGSSARPGLAVEMS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7" } ], "site_lbl": "Ser56" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "169", "end_pos": "169" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "996", "end_pos": "996" } ] }, { "type": "snv", "site_list": [ { "start_pos": "996", "end_pos": "996" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1149", "end_pos": "1149" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "453", "end_pos": "453" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "792", "end_pos": "792" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "Q148V7-1.54.54", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q148V7-1.792.792", "start_pos": 792, "end_pos": 792, "uniprot_canonical_ac": "Q148V7-1", "length": 1216, "uniprot_id": "RELCH_MOUSE", "protein_name": "RAB11-binding protein RELCH", "refseq_ac": "NP_083625", "refseq_name": "RAB11-binding protein RELCH isoform 2", "gene_name": "Relch", "gene_names_uniprotkb": "Relch; 2310035C23Rik; Kiaa1468", "gene_names_refseq": "2310035C23Rik; 6430401N10; Kiaa1468; Relch; mKIAA1468", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7" }, { "database": "iPTMnet", "id": "Q148V7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q148V7" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q148V7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q148V7", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KAKLHGEVPHIEVTRFPRPM", "down_seq": "PLQDVSTIIGSREQLAVLLQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q148V7", "url": "https://www.uniprot.org/uniprotkb/Q148V7" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q148V7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q148V7" } ], "site_lbl": "Ser792" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "169", "end_pos": "169" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "996", "end_pos": "996" } ] }, { "type": "snv", "site_list": [ { "start_pos": "996", "end_pos": "996" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1149", "end_pos": "1149" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "453", "end_pos": "453" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "792", "end_pos": "792" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9QZJ6-1.70.70", "start_pos": 70, "end_pos": 70, "uniprot_canonical_ac": "Q9QZJ6-1", "length": 164, "uniprot_id": "MFAP5_MOUSE", "protein_name": "Microfibrillar-associated protein 5", "refseq_ac": "NP_056591", "refseq_name": "microfibrillar-associated protein 5 isoform 1 precursor", "gene_name": "Mfap5", "gene_names_uniprotkb": "Mfap5; Magp2", "gene_names_refseq": "MAGP-2; MFAP-5; Mfap5", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9QZJ6", "url": "https://www.uniprot.org/uniprotkb/Q9QZJ6" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9QZJ6", "url": "https://www.uniprot.org/uniprotkb/Q9QZJ6", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "TDDTALADITPSTDDLAGDK", "down_seq": "ATAECRDEKFACTRLYSVHR", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn70", "evidence": [ { "id": "Q9QZJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9QZJ6#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "70", "end_pos": "70" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q5DTN8-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "Q5DTN8-1", "length": 844, "uniprot_id": "JKIP3_MOUSE", "protein_name": "Janus kinase and microtubule-interacting protein 3", "refseq_ac": "NP_082984", "refseq_name": "janus kinase and microtubule-interacting protein 3 isoform 1", "gene_name": "Jakmip3", "gene_names_uniprotkb": "Jakmip3; Kiaa4091; Necc2", "gene_names_refseq": "6330417G02Rik; Jakmip3; mKIAA4091", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q5DTN8", "url": "https://www.uniprot.org/uniprotkb/Q5DTN8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation is required for B cell homeostasis and antibody responses.", "journal": "Nature communications", "date": "2017", "authors": "Wu JL, Chiang MF, Hsu PH, Tsai DY, Hung KH, Wang YH, Angata T, Lin KI", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q5DTN8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q5DTN8" } ], "reference": [ { "type": "PubMed", "id": "29187734", "url": "https://glygen.org/publication/PubMed/29187734" } ] } ], "crossref": [ { "id": "29187734", "url": "https://glygen.org/publication/PubMed/29187734", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q5DTN8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q5DTN8", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "29187734", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29187734" }, { "id": "Q5DTN8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q5DTN8" } ] } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "384", "end_pos": "384" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q5DTN8-1.384.384", "start_pos": 384, "end_pos": 384, "uniprot_canonical_ac": "Q5DTN8-1", "length": 844, "uniprot_id": "JKIP3_MOUSE", "protein_name": "Janus kinase and microtubule-interacting protein 3", "refseq_ac": "NP_082984", "refseq_name": "janus kinase and microtubule-interacting protein 3 isoform 1", "gene_name": "Jakmip3", "gene_names_uniprotkb": "Jakmip3; Kiaa4091; Necc2", "gene_names_refseq": "6330417G02Rik; Jakmip3; mKIAA4091", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q5DTN8", "url": "https://www.uniprot.org/uniprotkb/Q5DTN8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q5DTN8", "url": "https://www.uniprot.org/uniprotkb/Q5DTN8" }, { "database": "iPTMnet", "id": "Q5DTN8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5DTN8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q5DTN8", "url": "https://www.uniprot.org/uniprotkb/Q5DTN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q5DTN8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5DTN8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "FVTQENIEMRQRAGIIRRPS", "down_seq": "LNDLDQSQDEREIDFLKLQI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q5DTN8", "url": "https://www.uniprot.org/uniprotkb/Q5DTN8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q5DTN8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5DTN8" } ], "site_lbl": "Ser384" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "384", "end_pos": "384" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q921M4-1.385.385", "start_pos": 385, "end_pos": 385, "uniprot_canonical_ac": "Q921M4-1", "length": 999, "uniprot_id": "GOGA2_MOUSE", "protein_name": "Golgin subfamily A member 2", "refseq_ac": "NP_001074437", "refseq_name": "golgin subfamily A member 2 isoform b", "gene_name": "Golga2", "gene_names_uniprotkb": "Golga2", "gene_names_refseq": "GM130; Golga2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q921M4", "url": "https://www.uniprot.org/uniprotkb/Q921M4" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation Is Essential for Rapid Pomc Expression and Cell Proliferation in Corticotropic Tumor Cells.", "journal": "Endocrinology", "date": "2021", "authors": "Massman LJ, Pereckas M, Zwagerman NT, Olivier-Van Stichelen S", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q921M4", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q921M4" } ], "reference": [ { "type": "PubMed", "id": "34418053", "url": "https://glygen.org/publication/PubMed/34418053" } ] } ], "crossref": [ { "id": "34418053", "url": "https://glygen.org/publication/PubMed/34418053", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q921M4", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q921M4", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LQHAMEERAQLETHVSQLME", "down_seq": "LKQLQVERDQYAENLKGESA", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser385", "evidence": [ { "id": "34418053", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34418053" }, { "id": "Q921M4", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q921M4" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "385", "end_pos": "385" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "81", "end_pos": "81" } ] }, { "type": "snv", "site_list": [ { "start_pos": "81", "end_pos": "81" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "273", "end_pos": "273" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "438", "end_pos": "438" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "934", "end_pos": "934" }, { "start_pos": "978", "end_pos": "978" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q921M4-1.686.686", "start_pos": 686, "end_pos": 686, "uniprot_canonical_ac": "Q921M4-1", "length": 999, "uniprot_id": "GOGA2_MOUSE", "protein_name": "Golgin subfamily A member 2", "refseq_ac": "NP_001074437", "refseq_name": "golgin subfamily A member 2 isoform b", "gene_name": "Golga2", "gene_names_uniprotkb": "Golga2", "gene_names_refseq": "GM130; Golga2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q921M4", "url": "https://www.uniprot.org/uniprotkb/Q921M4" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation Is Essential for Rapid Pomc Expression and Cell Proliferation in Corticotropic Tumor Cells.", "journal": "Endocrinology", "date": "2021", "authors": "Massman LJ, Pereckas M, Zwagerman NT, Olivier-Van Stichelen S", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q921M4", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q921M4" } ], "reference": [ { "type": "PubMed", "id": "34418053", "url": "https://glygen.org/publication/PubMed/34418053" } ] } ], "crossref": [ { "id": "34418053", "url": "https://glygen.org/publication/PubMed/34418053", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q921M4", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q921M4", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MAAELARQELQEAQERLKAT", "down_seq": "QENQQLQAQLSLLVLPGEGD", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser686", "evidence": [ { "id": "34418053", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34418053" }, { "id": "Q921M4", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q921M4" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "385", "end_pos": "385" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "81", "end_pos": "81" } ] }, { "type": "snv", "site_list": [ { "start_pos": "81", "end_pos": "81" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "273", "end_pos": "273" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "438", "end_pos": "438" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "934", "end_pos": "934" }, { "start_pos": "978", "end_pos": "978" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "upstream", "id": "Q921M4-1.697.697", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q921M4-1.81.81", "start_pos": 81, "end_pos": 81, "uniprot_canonical_ac": "Q921M4-1", "length": 999, "uniprot_id": "GOGA2_MOUSE", "protein_name": "Golgin subfamily A member 2", "refseq_ac": "NP_001074437", "refseq_name": "golgin subfamily A member 2 isoform b", "gene_name": "Golga2", "gene_names_uniprotkb": "Golga2", "gene_names_refseq": "GM130; Golga2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q921M4", "url": "https://www.uniprot.org/uniprotkb/Q921M4" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "rs212774029", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs212774029", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "ASDCQSPENVPTDHIAPAPP", "down_seq": "AATDTMFLGVTPSPDADLTQ", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr81", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "snv": [ { "evidence": [ { "id": "rs212774029", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs212774029" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "T", "sequence_mut": "A", "comment": "Germline mutation passed 1 filters: o-glyco-site-loss (T->A).", "chr_id": "2", "chr_pos": "32186671", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "T81", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "385", "end_pos": "385" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "81", "end_pos": "81" } ] }, { "type": "snv", "site_list": [ { "start_pos": "81", "end_pos": "81" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "273", "end_pos": "273" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "438", "end_pos": "438" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "934", "end_pos": "934" }, { "start_pos": "978", "end_pos": "978" } ] } ], "categories": [ "glycosylation_flag", "snv_flag" ], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "Q921M4-1.66.66", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q921M4-1.273.273", "start_pos": 273, "end_pos": 273, "uniprot_canonical_ac": "Q921M4-1", "length": 999, "uniprot_id": "GOGA2_MOUSE", "protein_name": "Golgin subfamily A member 2", "refseq_ac": "NP_001074437", "refseq_name": "golgin subfamily A member 2 isoform b", "gene_name": "Golga2", "gene_names_uniprotkb": "Golga2", "gene_names_refseq": "GM130; Golga2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q921M4", "url": "https://www.uniprot.org/uniprotkb/Q921M4" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q921M4", "url": "https://www.uniprot.org/uniprotkb/Q921M4", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DLASRLQSSRQRVGELERTL", "down_seq": "TVSTQQKQADRYNKDLTKER", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q921M4", "url": "https://www.uniprot.org/uniprotkb/Q921M4" } ], "site_lbl": "Ser273" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "385", "end_pos": "385" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "81", "end_pos": "81" } ] }, { "type": "snv", "site_list": [ { "start_pos": "81", "end_pos": "81" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "273", "end_pos": "273" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "438", "end_pos": "438" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "934", "end_pos": "934" }, { "start_pos": "978", "end_pos": "978" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q921M4-1.37.37", "start_pos": 37, "end_pos": 37, "uniprot_canonical_ac": "Q921M4-1", "length": 999, "uniprot_id": "GOGA2_MOUSE", "protein_name": "Golgin subfamily A member 2", "refseq_ac": "NP_001074437", "refseq_name": "golgin subfamily A member 2 isoform b", "gene_name": "Golga2", "gene_names_uniprotkb": "Golga2", "gene_names_refseq": "GM130; Golga2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q921M4", "url": "https://www.uniprot.org/uniprotkb/Q921M4" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q921M4", "url": "https://www.uniprot.org/uniprotkb/Q921M4", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TRQSKLAAAKKKLREYQQKN", "down_seq": "PGVPAGAKKKKKIKNGHSPE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q921M4", "url": "https://www.uniprot.org/uniprotkb/Q921M4" } ], "site_lbl": "Ser37" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "385", "end_pos": "385" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "81", "end_pos": "81" } ] }, { "type": "snv", "site_list": [ { "start_pos": "81", "end_pos": "81" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "273", "end_pos": "273" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "438", "end_pos": "438" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "934", "end_pos": "934" }, { "start_pos": "978", "end_pos": "978" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q921M4-1.438.438", "start_pos": 438, "end_pos": 438, "uniprot_canonical_ac": "Q921M4-1", "length": 999, "uniprot_id": "GOGA2_MOUSE", "protein_name": "Golgin subfamily A member 2", "refseq_ac": "NP_001074437", "refseq_name": "golgin subfamily A member 2 isoform b", "gene_name": "Golga2", "gene_names_uniprotkb": "Golga2", "gene_names_refseq": "GM130; Golga2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q921M4", "url": "https://www.uniprot.org/uniprotkb/Q921M4" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q921M4", "url": "https://www.uniprot.org/uniprotkb/Q921M4", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VHTLKEEKEHRERQVQELET", "down_seq": "LAALRSQMEEPPPPEPPAGP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q921M4", "url": "https://www.uniprot.org/uniprotkb/Q921M4" } ], "site_lbl": "Ser438" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "385", "end_pos": "385" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "81", "end_pos": "81" } ] }, { "type": "snv", "site_list": [ { "start_pos": "81", "end_pos": "81" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "273", "end_pos": "273" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "438", "end_pos": "438" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "934", "end_pos": "934" }, { "start_pos": "978", "end_pos": "978" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q921M4-1.66.66", "start_pos": 66, "end_pos": 66, "uniprot_canonical_ac": "Q921M4-1", "length": 999, "uniprot_id": "GOGA2_MOUSE", "protein_name": "Golgin subfamily A member 2", "refseq_ac": "NP_001074437", "refseq_name": "golgin subfamily A member 2 isoform b", "gene_name": "Golga2", "gene_names_uniprotkb": "Golga2", "gene_names_refseq": "GM130; Golga2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q921M4", "url": "https://www.uniprot.org/uniprotkb/Q921M4" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q921M4", "url": "https://www.uniprot.org/uniprotkb/Q921M4", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KKKKIKNGHSPERPTASDCQ", "down_seq": "PENVPTDHIAPAPPTAATDT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q921M4", "url": "https://www.uniprot.org/uniprotkb/Q921M4" } ], "site_lbl": "Ser66" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "385", "end_pos": "385" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "81", "end_pos": "81" } ] }, { "type": "snv", "site_list": [ { "start_pos": "81", "end_pos": "81" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "273", "end_pos": "273" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "438", "end_pos": "438" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "934", "end_pos": "934" }, { "start_pos": "978", "end_pos": "978" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "upstream", "id": "Q921M4-1.81.81", "categories": [ "glycosylation_flag", "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q921M4-1.697.697", "start_pos": 697, "end_pos": 697, "uniprot_canonical_ac": "Q921M4-1", "length": 999, "uniprot_id": "GOGA2_MOUSE", "protein_name": "Golgin subfamily A member 2", "refseq_ac": "NP_001074437", "refseq_name": "golgin subfamily A member 2 isoform b", "gene_name": "Golga2", "gene_names_uniprotkb": "Golga2", "gene_names_refseq": "GM130; Golga2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q921M4", "url": "https://www.uniprot.org/uniprotkb/Q921M4" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q921M4", "url": "https://www.uniprot.org/uniprotkb/Q921M4", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EAQERLKATSQENQQLQAQL", "down_seq": "LLVLPGEGDVDQEEEDEEVP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q921M4", "url": "https://www.uniprot.org/uniprotkb/Q921M4" } ], "site_lbl": "Ser697" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "385", "end_pos": "385" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "81", "end_pos": "81" } ] }, { "type": "snv", "site_list": [ { "start_pos": "81", "end_pos": "81" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "273", "end_pos": "273" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "438", "end_pos": "438" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "934", "end_pos": "934" }, { "start_pos": "978", "end_pos": "978" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "Q921M4-1.686.686", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q921M4-1.934.934", "start_pos": 934, "end_pos": 934, "uniprot_canonical_ac": "Q921M4-1", "length": 999, "uniprot_id": "GOGA2_MOUSE", "protein_name": "Golgin subfamily A member 2", "refseq_ac": "NP_001074437", "refseq_name": "golgin subfamily A member 2 isoform b", "gene_name": "Golga2", "gene_names_uniprotkb": "Golga2", "gene_names_refseq": "GM130; Golga2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q921M4", "url": "https://www.uniprot.org/uniprotkb/Q921M4" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q921M4", "url": "https://www.uniprot.org/uniprotkb/Q921M4", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VPTGSQEFGAADQQDDLREV", "down_seq": "LADDIEPAQGEAGVPAPHEN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q921M4", "url": "https://www.uniprot.org/uniprotkb/Q921M4" } ], "site_lbl": "Ser934" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "385", "end_pos": "385" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "81", "end_pos": "81" } ] }, { "type": "snv", "site_list": [ { "start_pos": "81", "end_pos": "81" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "273", "end_pos": "273" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "438", "end_pos": "438" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "934", "end_pos": "934" }, { "start_pos": "978", "end_pos": "978" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q921M4-1.978.978", "start_pos": 978, "end_pos": 978, "uniprot_canonical_ac": "Q921M4-1", "length": 999, "uniprot_id": "GOGA2_MOUSE", "protein_name": "Golgin subfamily A member 2", "refseq_ac": "NP_001074437", "refseq_name": "golgin subfamily A member 2 isoform b", "gene_name": "Golga2", "gene_names_uniprotkb": "Golga2", "gene_names_refseq": "GM130; Golga2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q921M4", "url": "https://www.uniprot.org/uniprotkb/Q921M4" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q921M4", "url": "https://www.uniprot.org/uniprotkb/Q921M4" }, { "database": "iPTMnet", "id": "Q921M4", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q921M4" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q921M4", "url": "https://www.uniprot.org/uniprotkb/Q921M4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q921M4", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q921M4", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QQIMQLLREIQNPRERPGLG", "down_seq": "NPCIPFFYRADENDEVKIMV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q921M4", "url": "https://www.uniprot.org/uniprotkb/Q921M4" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q921M4", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q921M4" } ], "site_lbl": "Ser978" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "385", "end_pos": "385" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "81", "end_pos": "81" } ] }, { "type": "snv", "site_list": [ { "start_pos": "81", "end_pos": "81" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "273", "end_pos": "273" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "438", "end_pos": "438" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "934", "end_pos": "934" }, { "start_pos": "978", "end_pos": "978" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "B1AXH1-1.172.172", "start_pos": 172, "end_pos": 172, "uniprot_canonical_ac": "B1AXH1-1", "length": 1219, "uniprot_id": "NHSL2_MOUSE", "protein_name": "NHS-like protein 2", "refseq_ac": "NP_001157082", "refseq_name": "NHS-like protein 2 isoform 1", "gene_name": "Nhsl2", "gene_names_uniprotkb": "Nhsl2", "gene_names_refseq": "1110062M06Rik; 6430511F03; EG621083; Gm10456; Nhsl2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "B1AXH1", "url": "https://www.uniprot.org/uniprotkb/B1AXH1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "YSEARLLGQTFRSSDGAPEP", "down_seq": "PSPRPQSAKRLEFVLMPAKR", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr172", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "172", "end_pos": "172" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "319", "end_pos": "319" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "722", "end_pos": "722" }, { "start_pos": "724", "end_pos": "724" } ] }, { "type": "snv", "site_list": [ { "start_pos": "359", "end_pos": "359" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1048", "end_pos": "1048" }, { "start_pos": "1208", "end_pos": "1208" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "690", "end_pos": "690" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "B1AXH1-1.290.290", "start_pos": 290, "end_pos": 290, "uniprot_canonical_ac": "B1AXH1-1", "length": 1219, "uniprot_id": "NHSL2_MOUSE", "protein_name": "NHS-like protein 2", "refseq_ac": "NP_001157082", "refseq_name": "NHS-like protein 2 isoform 1", "gene_name": "Nhsl2", "gene_names_uniprotkb": "Nhsl2", "gene_names_refseq": "1110062M06Rik; 6430511F03; EG621083; Gm10456; Nhsl2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "B1AXH1", "url": "https://www.uniprot.org/uniprotkb/B1AXH1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "ETAVNPKSTLRRRRTIIGFS", "down_seq": "FSQRDQGHSSSPTGSLARSA", "glycosylation": [ { "glytoucan_ac": "G23719VF", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "RTIIGFSNFSQR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn290", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "172", "end_pos": "172" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "319", "end_pos": "319" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "722", "end_pos": "722" }, { "start_pos": "724", "end_pos": "724" } ] }, { "type": "snv", "site_list": [ { "start_pos": "359", "end_pos": "359" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1048", "end_pos": "1048" }, { "start_pos": "1208", "end_pos": "1208" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "690", "end_pos": "690" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "B1AXH1-1.319.319", "start_pos": 319, "end_pos": 319, "uniprot_canonical_ac": "B1AXH1-1", "length": 1219, "uniprot_id": "NHSL2_MOUSE", "protein_name": "NHS-like protein 2", "refseq_ac": "NP_001157082", "refseq_name": "NHS-like protein 2 isoform 1", "gene_name": "Nhsl2", "gene_names_uniprotkb": "Nhsl2", "gene_names_refseq": "1110062M06Rik; 6430511F03; EG621083; Gm10456; Nhsl2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "B1AXH1", "url": "https://www.uniprot.org/uniprotkb/B1AXH1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "B1AXH1", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=B1AXH1" }, { "database": "O-GlcNAc Atlas", "id": "B1AXH1", "url": "https://oglcnac.org/atlas/detail/B1AXH1" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] } ], "crossref": [ { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "B1AXH1", "url": "https://oglcnac.org/atlas/detail/B1AXH1", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SSSPTGSLARSATSDIRPGH", "down_seq": "APQVVQGRVAVGQEARFPSL", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser319", "evidence": [ { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "B1AXH1", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/B1AXH1" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "172", "end_pos": "172" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "319", "end_pos": "319" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "722", "end_pos": "722" }, { "start_pos": "724", "end_pos": "724" } ] }, { "type": "snv", "site_list": [ { "start_pos": "359", "end_pos": "359" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1048", "end_pos": "1048" }, { "start_pos": "1208", "end_pos": "1208" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "690", "end_pos": "690" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "B1AXH1-1.383.383", "start_pos": 383, "end_pos": 383, "uniprot_canonical_ac": "B1AXH1-1", "length": 1219, "uniprot_id": "NHSL2_MOUSE", "protein_name": "NHS-like protein 2", "refseq_ac": "NP_001157082", "refseq_name": "NHS-like protein 2 isoform 1", "gene_name": "Nhsl2", "gene_names_uniprotkb": "Nhsl2", "gene_names_refseq": "1110062M06Rik; 6430511F03; EG621083; Gm10456; Nhsl2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "B1AXH1", "url": "https://www.uniprot.org/uniprotkb/B1AXH1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "HPGMESMAVVYSVPSSCNGP", "down_seq": "ESTFSTSWKGDAFTYMTPSA", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr383", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "172", "end_pos": "172" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "319", "end_pos": "319" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "722", "end_pos": "722" }, { "start_pos": "724", "end_pos": "724" } ] }, { "type": "snv", "site_list": [ { "start_pos": "359", "end_pos": "359" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1048", "end_pos": "1048" }, { "start_pos": "1208", "end_pos": "1208" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "690", "end_pos": "690" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "B1AXH1-1.722.722", "start_pos": 722, "end_pos": 722, "uniprot_canonical_ac": "B1AXH1-1", "length": 1219, "uniprot_id": "NHSL2_MOUSE", "protein_name": "NHS-like protein 2", "refseq_ac": "NP_001157082", "refseq_name": "NHS-like protein 2 isoform 1", "gene_name": "Nhsl2", "gene_names_uniprotkb": "Nhsl2", "gene_names_refseq": "1110062M06Rik; 6430511F03; EG621083; Gm10456; Nhsl2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "B1AXH1", "url": "https://www.uniprot.org/uniprotkb/B1AXH1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "GRPTGLMSPSSGYSSQSETP", "down_seq": "PTVSMSLTLGHLPPPSASVR", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr722", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "172", "end_pos": "172" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "319", "end_pos": "319" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "722", "end_pos": "722" }, { "start_pos": "724", "end_pos": "724" } ] }, { "type": "snv", "site_list": [ { "start_pos": "359", "end_pos": "359" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1048", "end_pos": "1048" }, { "start_pos": "1208", "end_pos": "1208" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "690", "end_pos": "690" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "B1AXH1-1.724.724", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "B1AXH1-1.724.724", "start_pos": 724, "end_pos": 724, "uniprot_canonical_ac": "B1AXH1-1", "length": 1219, "uniprot_id": "NHSL2_MOUSE", "protein_name": "NHS-like protein 2", "refseq_ac": "NP_001157082", "refseq_name": "NHS-like protein 2 isoform 1", "gene_name": "Nhsl2", "gene_names_uniprotkb": "Nhsl2", "gene_names_refseq": "1110062M06Rik; 6430511F03; EG621083; Gm10456; Nhsl2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "B1AXH1", "url": "https://www.uniprot.org/uniprotkb/B1AXH1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "PTGLMSPSSGYSSQSETPTP", "down_seq": "VSMSLTLGHLPPPSASVRVR", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr724", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "172", "end_pos": "172" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "319", "end_pos": "319" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "722", "end_pos": "722" }, { "start_pos": "724", "end_pos": "724" } ] }, { "type": "snv", "site_list": [ { "start_pos": "359", "end_pos": "359" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1048", "end_pos": "1048" }, { "start_pos": "1208", "end_pos": "1208" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "690", "end_pos": "690" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "B1AXH1-1.722.722", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "B1AXH1-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "B1AXH1-1", "length": 1219, "uniprot_id": "NHSL2_MOUSE", "protein_name": "NHS-like protein 2", "refseq_ac": "NP_001157082", "refseq_name": "NHS-like protein 2 isoform 1", "gene_name": "Nhsl2", "gene_names_uniprotkb": "Nhsl2", "gene_names_refseq": "1110062M06Rik; 6430511F03; EG621083; Gm10456; Nhsl2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "B1AXH1", "url": "https://www.uniprot.org/uniprotkb/B1AXH1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "B1AXH1", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=B1AXH1" }, { "database": "O-GlcNAc Atlas", "id": "B1AXH1", "url": "https://oglcnac.org/atlas/detail/B1AXH1" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases.", "journal": "Frontiers in aging", "date": "2021", "authors": "Huynh Van N, Wang Sheng, Ouyang Xiaosen, Wani Willayat Y, Johnson Michelle S, Chacko Balu K, Jegga Anil G, Qian Wei-Jun, Chatham John C, Darley-Usmar Victor M, Zhang Jianhua", "evidence": [ { "database": "O-GlcNAc Database", "id": "B1AXH1", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=B1AXH1" } ], "reference": [ { "type": "PubMed", "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049" } ] } ], "crossref": [ { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "B1AXH1", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=B1AXH1", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049", "database": "PubMed", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "B1AXH1", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=B1AXH1" }, { "id": "35822049", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/35822049" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "172", "end_pos": "172" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "319", "end_pos": "319" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "722", "end_pos": "722" }, { "start_pos": "724", "end_pos": "724" } ] }, { "type": "snv", "site_list": [ { "start_pos": "359", "end_pos": "359" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1048", "end_pos": "1048" }, { "start_pos": "1208", "end_pos": "1208" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "690", "end_pos": "690" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "B1AXH1-1.359.359", "start_pos": 359, "end_pos": 359, "uniprot_canonical_ac": "B1AXH1-1", "length": 1219, "uniprot_id": "NHSL2_MOUSE", "protein_name": "NHS-like protein 2", "refseq_ac": "NP_001157082", "refseq_name": "NHS-like protein 2 isoform 1", "gene_name": "Nhsl2", "gene_names_uniprotkb": "Nhsl2", "gene_names_refseq": "1110062M06Rik; 6430511F03; EG621083; Gm10456; Nhsl2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "B1AXH1", "url": "https://www.uniprot.org/uniprotkb/B1AXH1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3389528032", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389528032", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LTSPGLRHSSSEPGDAHQAR", "down_seq": "ASDHPGMESMAVVYSVPSSC", "snv": [ { "evidence": [ { "id": "rs3389528032", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389528032" } ], "glycoeffect": [ "n-glyco-sequon-gain", "o-glyco-site-loss" ], "sequence_org": "S", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (SAS->NAS).", "chr_id": "X", "chr_pos": "101121274", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S359", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "172", "end_pos": "172" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "319", "end_pos": "319" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "722", "end_pos": "722" }, { "start_pos": "724", "end_pos": "724" } ] }, { "type": "snv", "site_list": [ { "start_pos": "359", "end_pos": "359" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1048", "end_pos": "1048" }, { "start_pos": "1208", "end_pos": "1208" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "690", "end_pos": "690" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "B1AXH1-1.1048.1048", "start_pos": 1048, "end_pos": 1048, "uniprot_canonical_ac": "B1AXH1-1", "length": 1219, "uniprot_id": "NHSL2_MOUSE", "protein_name": "NHS-like protein 2", "refseq_ac": "NP_001157082", "refseq_name": "NHS-like protein 2 isoform 1", "gene_name": "Nhsl2", "gene_names_uniprotkb": "Nhsl2", "gene_names_refseq": "1110062M06Rik; 6430511F03; EG621083; Gm10456; Nhsl2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "B1AXH1", "url": "https://www.uniprot.org/uniprotkb/B1AXH1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "B1AXH1", "url": "https://www.uniprot.org/uniprotkb/B1AXH1" }, { "database": "iPTMnet", "id": "B1AXH1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/B1AXH1" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "B1AXH1", "url": "https://www.uniprot.org/uniprotkb/B1AXH1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "B1AXH1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/B1AXH1", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SPIITLEEDGKCPSTGDDQK", "down_seq": "PGKGVTSPLHTDTEKEAISP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "B1AXH1", "url": "https://www.uniprot.org/uniprotkb/B1AXH1" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "B1AXH1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/B1AXH1" } ], "site_lbl": "Ser1048" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "172", "end_pos": "172" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "319", "end_pos": "319" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "722", "end_pos": "722" }, { "start_pos": "724", "end_pos": "724" } ] }, { "type": "snv", "site_list": [ { "start_pos": "359", "end_pos": "359" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1048", "end_pos": "1048" }, { "start_pos": "1208", "end_pos": "1208" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "690", "end_pos": "690" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "B1AXH1-1.1208.1208", "start_pos": 1208, "end_pos": 1208, "uniprot_canonical_ac": "B1AXH1-1", "length": 1219, "uniprot_id": "NHSL2_MOUSE", "protein_name": "NHS-like protein 2", "refseq_ac": "NP_001157082", "refseq_name": "NHS-like protein 2 isoform 1", "gene_name": "Nhsl2", "gene_names_uniprotkb": "Nhsl2", "gene_names_refseq": "1110062M06Rik; 6430511F03; EG621083; Gm10456; Nhsl2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "B1AXH1", "url": "https://www.uniprot.org/uniprotkb/B1AXH1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "B1AXH1", "url": "https://www.uniprot.org/uniprotkb/B1AXH1" }, { "database": "iPTMnet", "id": "B1AXH1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/B1AXH1" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "B1AXH1", "url": "https://www.uniprot.org/uniprotkb/B1AXH1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "B1AXH1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/B1AXH1", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SAAELLKTTNPLARRIIAQF", "down_seq": "KDYEPTDNPST", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "B1AXH1", "url": "https://www.uniprot.org/uniprotkb/B1AXH1" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "B1AXH1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/B1AXH1" } ], "site_lbl": "Ser1208" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "172", "end_pos": "172" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "319", "end_pos": "319" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "722", "end_pos": "722" }, { "start_pos": "724", "end_pos": "724" } ] }, { "type": "snv", "site_list": [ { "start_pos": "359", "end_pos": "359" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1048", "end_pos": "1048" }, { "start_pos": "1208", "end_pos": "1208" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "690", "end_pos": "690" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "B1AXH1-1.499.499", "start_pos": 499, "end_pos": 499, "uniprot_canonical_ac": "B1AXH1-1", "length": 1219, "uniprot_id": "NHSL2_MOUSE", "protein_name": "NHS-like protein 2", "refseq_ac": "NP_001157082", "refseq_name": "NHS-like protein 2 isoform 1", "gene_name": "Nhsl2", "gene_names_uniprotkb": "Nhsl2", "gene_names_refseq": "1110062M06Rik; 6430511F03; EG621083; Gm10456; Nhsl2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "B1AXH1", "url": "https://www.uniprot.org/uniprotkb/B1AXH1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "B1AXH1", "url": "https://www.uniprot.org/uniprotkb/B1AXH1" }, { "database": "iPTMnet", "id": "B1AXH1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/B1AXH1" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "B1AXH1", "url": "https://www.uniprot.org/uniprotkb/B1AXH1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "B1AXH1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/B1AXH1", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GTSRLETGPGGTNRFRERSL", "down_seq": "VPTDSGVTSVDYDEEQKTSE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "B1AXH1", "url": "https://www.uniprot.org/uniprotkb/B1AXH1" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "B1AXH1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/B1AXH1" } ], "site_lbl": "Ser499" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "172", "end_pos": "172" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "319", "end_pos": "319" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "722", "end_pos": "722" }, { "start_pos": "724", "end_pos": "724" } ] }, { "type": "snv", "site_list": [ { "start_pos": "359", "end_pos": "359" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1048", "end_pos": "1048" }, { "start_pos": "1208", "end_pos": "1208" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "690", "end_pos": "690" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "B1AXH1-1.575.575", "start_pos": 575, "end_pos": 575, "uniprot_canonical_ac": "B1AXH1-1", "length": 1219, "uniprot_id": "NHSL2_MOUSE", "protein_name": "NHS-like protein 2", "refseq_ac": "NP_001157082", "refseq_name": "NHS-like protein 2 isoform 1", "gene_name": "Nhsl2", "gene_names_uniprotkb": "Nhsl2", "gene_names_refseq": "1110062M06Rik; 6430511F03; EG621083; Gm10456; Nhsl2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "B1AXH1", "url": "https://www.uniprot.org/uniprotkb/B1AXH1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "B1AXH1", "url": "https://www.uniprot.org/uniprotkb/B1AXH1" }, { "database": "iPTMnet", "id": "B1AXH1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/B1AXH1" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "B1AXH1", "url": "https://www.uniprot.org/uniprotkb/B1AXH1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "B1AXH1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/B1AXH1", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SKSISLKKAKKKPSPPMRSV", "down_seq": "LVKDEPALPPEGELVLPKDQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "B1AXH1", "url": "https://www.uniprot.org/uniprotkb/B1AXH1" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "B1AXH1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/B1AXH1" } ], "site_lbl": "Ser575" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "172", "end_pos": "172" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "319", "end_pos": "319" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "722", "end_pos": "722" }, { "start_pos": "724", "end_pos": "724" } ] }, { "type": "snv", "site_list": [ { "start_pos": "359", "end_pos": "359" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1048", "end_pos": "1048" }, { "start_pos": "1208", "end_pos": "1208" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "690", "end_pos": "690" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "B1AXH1-1.690.690", "start_pos": 690, "end_pos": 690, "uniprot_canonical_ac": "B1AXH1-1", "length": 1219, "uniprot_id": "NHSL2_MOUSE", "protein_name": "NHS-like protein 2", "refseq_ac": "NP_001157082", "refseq_name": "NHS-like protein 2 isoform 1", "gene_name": "Nhsl2", "gene_names_uniprotkb": "Nhsl2", "gene_names_refseq": "1110062M06Rik; 6430511F03; EG621083; Gm10456; Nhsl2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "B1AXH1", "url": "https://www.uniprot.org/uniprotkb/B1AXH1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "B1AXH1", "url": "https://www.uniprot.org/uniprotkb/B1AXH1" }, { "database": "iPTMnet", "id": "B1AXH1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/B1AXH1" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "B1AXH1", "url": "https://www.uniprot.org/uniprotkb/B1AXH1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "B1AXH1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/B1AXH1", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GSSESLASPSTSRATTPSQL", "down_seq": "IEVEAREVASPGRPTGLMSP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "B1AXH1", "url": "https://www.uniprot.org/uniprotkb/B1AXH1" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "B1AXH1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/B1AXH1" } ], "site_lbl": "Ser690" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "172", "end_pos": "172" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "319", "end_pos": "319" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "722", "end_pos": "722" }, { "start_pos": "724", "end_pos": "724" } ] }, { "type": "snv", "site_list": [ { "start_pos": "359", "end_pos": "359" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1048", "end_pos": "1048" }, { "start_pos": "1208", "end_pos": "1208" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "690", "end_pos": "690" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P30275-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "P30275-1", "length": 418, "uniprot_id": "KCRU_MOUSE", "protein_name": "Creatine kinase U-type, mitochondrial", "refseq_ac": "NP_034027", "refseq_name": "creatine kinase U-type, mitochondrial isoform 1 precursor", "gene_name": "Ckmt1", "gene_names_uniprotkb": "Ckmt1", "gene_names_refseq": "Ckmt1; Mt-CK; ScCKmit; U-MtCK; UbCKmit; mi-CK; mia-CK", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P30275", "url": "https://www.uniprot.org/uniprotkb/P30275" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Enhancing protein O-GlcNAcylation in down syndrome mice mitigates memory dysfunctions through the rescue of mitochondrial bioenergetics, stress responses and pathological markers.", "journal": "Redox biology", "date": "2025-07-16", "authors": "Lanzillotta Chiara, Prestia Francesca, Greco Viviana, Iavarone Federica, Cordella Federica, Sette Chiara, Forte Elena, Tramutola Antonella, Lanzillotta Simona, Cassano Tommaso, Di Angelantonio Silvia, Urbani Andrea, Barone Eugenio, Perluigi Marzia, Di Domenico Fabio", "evidence": [ { "database": "O-GlcNAc Database", "id": "P30275", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P30275" } ], "reference": [ { "type": "PubMed", "id": "40684658", "url": "https://glygen.org/publication/PubMed/40684658" } ] }, { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "P30275", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P30275" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] } ], "crossref": [ { "id": "40684658", "url": "https://glygen.org/publication/PubMed/40684658", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P30275", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P30275", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "40684658", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40684658" }, { "id": "P30275", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P30275" }, { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" } ] } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "152", "end_pos": "152" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "366", "end_pos": "366" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P30275-1.152.152", "start_pos": 152, "end_pos": 152, "uniprot_canonical_ac": "P30275-1", "length": 418, "uniprot_id": "KCRU_MOUSE", "protein_name": "Creatine kinase U-type, mitochondrial", "refseq_ac": "NP_034027", "refseq_name": "creatine kinase U-type, mitochondrial isoform 1 precursor", "gene_name": "Ckmt1", "gene_names_uniprotkb": "Ckmt1", "gene_names_refseq": "Ckmt1; Mt-CK; ScCKmit; U-MtCK; UbCKmit; mi-CK; mia-CK", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P30275", "url": "https://www.uniprot.org/uniprotkb/P30275" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P30275", "url": "https://www.uniprot.org/uniprotkb/P30275", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NGYDPRTMKHTTDLDASKIR", "down_seq": "GYFDERYVLSSRVRTGRSIR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P30275", "url": "https://www.uniprot.org/uniprotkb/P30275" } ], "site_lbl": "Ser152" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "152", "end_pos": "152" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "366", "end_pos": "366" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P30275-1.197.197", "start_pos": 197, "end_pos": 197, "uniprot_canonical_ac": "P30275-1", "length": 418, "uniprot_id": "KCRU_MOUSE", "protein_name": "Creatine kinase U-type, mitochondrial", "refseq_ac": "NP_034027", "refseq_name": "creatine kinase U-type, mitochondrial isoform 1 precursor", "gene_name": "Ckmt1", "gene_names_uniprotkb": "Ckmt1", "gene_names_refseq": "Ckmt1; Mt-CK; ScCKmit; U-MtCK; UbCKmit; mi-CK; mia-CK", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P30275", "url": "https://www.uniprot.org/uniprotkb/P30275" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P30275", "url": "https://www.uniprot.org/uniprotkb/P30275", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PPACTRAERREVERVVVDAL", "down_seq": "GLKGDLAGRYYRLSEMTEAE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P30275", "url": "https://www.uniprot.org/uniprotkb/P30275" } ], "site_lbl": "Ser197" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "152", "end_pos": "152" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "366", "end_pos": "366" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "upstream", "id": "P30275-1.214.214", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P30275-1.214.214", "start_pos": 214, "end_pos": 214, "uniprot_canonical_ac": "P30275-1", "length": 418, "uniprot_id": "KCRU_MOUSE", "protein_name": "Creatine kinase U-type, mitochondrial", "refseq_ac": "NP_034027", "refseq_name": "creatine kinase U-type, mitochondrial isoform 1 precursor", "gene_name": "Ckmt1", "gene_names_uniprotkb": "Ckmt1", "gene_names_refseq": "Ckmt1; Mt-CK; ScCKmit; U-MtCK; UbCKmit; mi-CK; mia-CK", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P30275", "url": "https://www.uniprot.org/uniprotkb/P30275" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P30275", "url": "https://www.uniprot.org/uniprotkb/P30275", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "DALSGLKGDLAGRYYRLSEM", "down_seq": "EAEQQQLIDDHFLFDKPVSP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P30275", "url": "https://www.uniprot.org/uniprotkb/P30275" } ], "site_lbl": "Thr214" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "152", "end_pos": "152" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "366", "end_pos": "366" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P30275-1.197.197", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P30275-1.233.233", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P30275-1.233.233", "start_pos": 233, "end_pos": 233, "uniprot_canonical_ac": "P30275-1", "length": 418, "uniprot_id": "KCRU_MOUSE", "protein_name": "Creatine kinase U-type, mitochondrial", "refseq_ac": "NP_034027", "refseq_name": "creatine kinase U-type, mitochondrial isoform 1 precursor", "gene_name": "Ckmt1", "gene_names_uniprotkb": "Ckmt1", "gene_names_refseq": "Ckmt1; Mt-CK; ScCKmit; U-MtCK; UbCKmit; mi-CK; mia-CK", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P30275", "url": "https://www.uniprot.org/uniprotkb/P30275" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P30275", "url": "https://www.uniprot.org/uniprotkb/P30275" }, { "database": "iPTMnet", "id": "P30275", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30275" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "P30275", "url": "https://www.uniprot.org/uniprotkb/P30275", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P30275", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30275", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MTEAEQQQLIDDHFLFDKPV", "down_seq": "PLLTAAGMARDWPDARGIWH", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P30275", "url": "https://www.uniprot.org/uniprotkb/P30275" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "P30275", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30275" } ], "site_lbl": "Ser233" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "152", "end_pos": "152" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "366", "end_pos": "366" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P30275-1.214.214", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P30275-1.356.356", "start_pos": 356, "end_pos": 356, "uniprot_canonical_ac": "P30275-1", "length": 418, "uniprot_id": "KCRU_MOUSE", "protein_name": "Creatine kinase U-type, mitochondrial", "refseq_ac": "NP_034027", "refseq_name": "creatine kinase U-type, mitochondrial isoform 1 precursor", "gene_name": "Ckmt1", "gene_names_uniprotkb": "Ckmt1", "gene_names_refseq": "Ckmt1; Mt-CK; ScCKmit; U-MtCK; UbCKmit; mi-CK; mia-CK", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P30275", "url": "https://www.uniprot.org/uniprotkb/P30275" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P30275", "url": "https://www.uniprot.org/uniprotkb/P30275", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "LSKDNRFPKILENLRLQKRG", "down_seq": "GGVDTAATGSVFDISNLDRL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P30275", "url": "https://www.uniprot.org/uniprotkb/P30275" } ], "site_lbl": "Thr356" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "152", "end_pos": "152" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "366", "end_pos": "366" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "upstream", "id": "P30275-1.366.366", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P30275-1.366.366", "start_pos": 366, "end_pos": 366, "uniprot_canonical_ac": "P30275-1", "length": 418, "uniprot_id": "KCRU_MOUSE", "protein_name": "Creatine kinase U-type, mitochondrial", "refseq_ac": "NP_034027", "refseq_name": "creatine kinase U-type, mitochondrial isoform 1 precursor", "gene_name": "Ckmt1", "gene_names_uniprotkb": "Ckmt1", "gene_names_refseq": "Ckmt1; Mt-CK; ScCKmit; U-MtCK; UbCKmit; mi-CK; mia-CK", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P30275", "url": "https://www.uniprot.org/uniprotkb/P30275" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P30275", "url": "https://www.uniprot.org/uniprotkb/P30275" }, { "database": "iPTMnet", "id": "P30275", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30275" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "P30275", "url": "https://www.uniprot.org/uniprotkb/P30275", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P30275", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30275", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LENLRLQKRGTGGVDTAATG", "down_seq": "VFDISNLDRLGKSEVELVQL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P30275", "url": "https://www.uniprot.org/uniprotkb/P30275" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "P30275", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30275" } ], "site_lbl": "Ser366" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "152", "end_pos": "152" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "366", "end_pos": "366" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "P30275-1.356.356", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q924H2-1.93.93", "start_pos": 93, "end_pos": 93, "uniprot_canonical_ac": "Q924H2-1", "length": 789, "uniprot_id": "MED15_MOUSE", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_291087", "refseq_name": "mediator of RNA polymerase II transcription subunit 15 isoform a", "gene_name": "Med15", "gene_names_uniprotkb": "Med15; MED15; Pcqap", "gene_names_refseq": "A230074L19Rik; Med15; Pcqap; mPcqap", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q924H2", "url": "https://www.uniprot.org/uniprotkb/Q924H2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "KSQASVSDPMNALQSLTGGP", "down_seq": "PGAAGIGMPPRGPGQSLGGM", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr93", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "93", "end_pos": "93" } ] }, { "type": "snv", "site_list": [ { "start_pos": "312", "end_pos": "312" }, { "start_pos": "55", "end_pos": "55" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "604", "end_pos": "604" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q924H2-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "Q924H2-1", "length": 789, "uniprot_id": "MED15_MOUSE", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_291087", "refseq_name": "mediator of RNA polymerase II transcription subunit 15 isoform a", "gene_name": "Med15", "gene_names_uniprotkb": "Med15; MED15; Pcqap", "gene_names_refseq": "A230074L19Rik; Med15; Pcqap; mPcqap", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q924H2", "url": "https://www.uniprot.org/uniprotkb/Q924H2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q924H2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q924H2" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Myers SA, Panning B, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q924H2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q924H2" } ], "reference": [ { "type": "PubMed", "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357" } ] } ], "crossref": [ { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q924H2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q924H2", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357", "database": "PubMed", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "Q924H2", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q924H2" }, { "id": "21606357", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/21606357" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "93", "end_pos": "93" } ] }, { "type": "snv", "site_list": [ { "start_pos": "312", "end_pos": "312" }, { "start_pos": "55", "end_pos": "55" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "604", "end_pos": "604" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q924H2-1.312.312", "start_pos": 312, "end_pos": 312, "uniprot_canonical_ac": "Q924H2-1", "length": 789, "uniprot_id": "MED15_MOUSE", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_291087", "refseq_name": "mediator of RNA polymerase II transcription subunit 15 isoform a", "gene_name": "Med15", "gene_names_uniprotkb": "Med15; MED15; Pcqap", "gene_names_refseq": "A230074L19Rik; Med15; Pcqap; mPcqap", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q924H2", "url": "https://www.uniprot.org/uniprotkb/Q924H2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3389353858", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389353858", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "P", "start_aa": "P", "up_seq": "HPQHHQPPPQAQQSPIAQNQ", "down_seq": "PQIPPQSQSQPLVSQAQALP", "snv": [ { "evidence": [ { "id": "rs3389353858", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389353858" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "P", "sequence_mut": "S", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (NQP->NQS).", "chr_id": "16", "chr_pos": "17473570", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "P312", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "93", "end_pos": "93" } ] }, { "type": "snv", "site_list": [ { "start_pos": "312", "end_pos": "312" }, { "start_pos": "55", "end_pos": "55" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "604", "end_pos": "604" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q924H2-1.55.55", "start_pos": 55, "end_pos": 55, "uniprot_canonical_ac": "Q924H2-1", "length": 789, "uniprot_id": "MED15_MOUSE", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_291087", "refseq_name": "mediator of RNA polymerase II transcription subunit 15 isoform a", "gene_name": "Med15", "gene_names_uniprotkb": "Med15; MED15; Pcqap", "gene_names_refseq": "A230074L19Rik; Med15; Pcqap; mPcqap", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q924H2", "url": "https://www.uniprot.org/uniprotkb/Q924H2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3389384394", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389384394", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "SKSSKDMESHVFLKAKTRDE", "down_seq": "LSLVARLIIHFRDIHNKKSQ", "snv": [ { "evidence": [ { "id": "rs3389384394", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389384394" } ], "glycoeffect": [ "n-glyco-sequon-gain", "o-glyco-site-loss" ], "sequence_org": "Y", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (YLS->NLS).", "chr_id": "16", "chr_pos": "17503362", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "Y55", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "93", "end_pos": "93" } ] }, { "type": "snv", "site_list": [ { "start_pos": "312", "end_pos": "312" }, { "start_pos": "55", "end_pos": "55" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "604", "end_pos": "604" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q924H2-1.604.604", "start_pos": 604, "end_pos": 604, "uniprot_canonical_ac": "Q924H2-1", "length": 789, "uniprot_id": "MED15_MOUSE", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_291087", "refseq_name": "mediator of RNA polymerase II transcription subunit 15 isoform a", "gene_name": "Med15", "gene_names_uniprotkb": "Med15; MED15; Pcqap", "gene_names_refseq": "A230074L19Rik; Med15; Pcqap; mPcqap", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q924H2", "url": "https://www.uniprot.org/uniprotkb/Q924H2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q924H2", "url": "https://www.uniprot.org/uniprotkb/Q924H2" }, { "database": "iPTMnet", "id": "Q924H2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q924H2" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q924H2", "url": "https://www.uniprot.org/uniprotkb/Q924H2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q924H2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q924H2", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "KTLQKCEIALEKLKNDMAVP", "down_seq": "PPPPPVLPTKQQDLCQPLLD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q924H2", "url": "https://www.uniprot.org/uniprotkb/Q924H2" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q924H2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q924H2" } ], "site_lbl": "Thr604" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "93", "end_pos": "93" } ] }, { "type": "snv", "site_list": [ { "start_pos": "312", "end_pos": "312" }, { "start_pos": "55", "end_pos": "55" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "604", "end_pos": "604" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9ERH7-1.226.226", "start_pos": 226, "end_pos": 226, "uniprot_canonical_ac": "Q9ERH7-1", "length": 1192, "uniprot_id": "HIPK3_MOUSE", "protein_name": "Homeodomain-interacting protein kinase 3", "refseq_ac": "NP_034564", "refseq_name": "homeodomain-interacting protein kinase 3 isoform 1", "gene_name": "Hipk3", "gene_names_uniprotkb": "Hipk3; Fist3", "gene_names_refseq": "DYRK6; FIST3; Hipk3; PKY; mir-1902", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ERH7", "url": "https://www.uniprot.org/uniprotkb/Q9ERH7" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Cyclic AMP stimulates SF-1-dependent CYP11A1 expression through homeodomain-interacting protein kinase 3-mediated Jun N-terminal kinase and c-Jun phosphorylation.", "journal": "Molecular and cellular biology", "date": "2007", "authors": "Lan HC, Li HJ, Lin G, Lai PY, Chung BC", "evidence": [ { "database": "UniProtKB", "id": "Q9ERH7", "url": "https://www.uniprot.org/uniprotkb/Q9ERH7" } ], "reference": [ { "type": "PubMed", "id": "17210646", "url": "https://glygen.org/publication/PubMed/17210646" } ] }, { "title": "FIST/HIPK3: a Fas/FADD-interacting serine/threonine kinase that induces FADD phosphorylation and inhibits fas-mediated Jun NH(2)-terminal kinase activation.", "journal": "The Journal of experimental medicine", "date": "2000", "authors": "Rochat-Steiner V, Becker K, Micheau O, Schneider P, Burns K, Tschopp J", "evidence": [ { "database": "UniProtKB", "id": "Q9ERH7", "url": "https://www.uniprot.org/uniprotkb/Q9ERH7" } ], "reference": [ { "type": "PubMed", "id": "11034606", "url": "https://glygen.org/publication/PubMed/11034606" } ] } ], "crossref": [ { "id": "Q9ERH7", "url": "https://www.uniprot.org/uniprotkb/Q9ERH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17210646", "url": "https://glygen.org/publication/PubMed/17210646", "database": "PubMed", "categories": [ "Other" ] }, { "id": "11034606", "url": "https://glygen.org/publication/PubMed/11034606", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "GTFGQVVKCWKRGTNEIVAI", "down_seq": "ILKNHPSYARQGQIEVSILA", "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "R", "comment": "Loss of kinase activity and impaired activation of SF1.", "evidence": [ { "database": "UniProtKB", "id": "Q9ERH7", "url": "https://www.uniprot.org/uniprotkb/Q9ERH7" }, { "database": "PubMed", "id": "17210646", "url": "https://glygen.org/publication/PubMed/17210646" }, { "database": "PubMed", "id": "11034606", "url": "https://glygen.org/publication/PubMed/11034606" } ] }, { "sequence_org": "K", "sequence_mut": "S", "comment": "Impairs catalytic activity.", "evidence": [ { "database": "UniProtKB", "id": "Q9ERH7", "url": "https://www.uniprot.org/uniprotkb/Q9ERH7" }, { "database": "PubMed", "id": "11034606", "url": "https://glygen.org/publication/PubMed/11034606" }, { "database": "PubMed", "id": "17210646", "url": "https://glygen.org/publication/PubMed/17210646" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "226", "end_pos": "226" }, { "start_pos": "322", "end_pos": "322" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "359", "end_pos": "359" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9ERH7-1.322.322", "start_pos": 322, "end_pos": 322, "uniprot_canonical_ac": "Q9ERH7-1", "length": 1192, "uniprot_id": "HIPK3_MOUSE", "protein_name": "Homeodomain-interacting protein kinase 3", "refseq_ac": "NP_034564", "refseq_name": "homeodomain-interacting protein kinase 3 isoform 1", "gene_name": "Hipk3", "gene_names_uniprotkb": "Hipk3; Fist3", "gene_names_refseq": "DYRK6; FIST3; Hipk3; PKY; mir-1902", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ERH7", "url": "https://www.uniprot.org/uniprotkb/Q9ERH7" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "FIST/HIPK3: a Fas/FADD-interacting serine/threonine kinase that induces FADD phosphorylation and inhibits fas-mediated Jun NH(2)-terminal kinase activation.", "journal": "The Journal of experimental medicine", "date": "2000", "authors": "Rochat-Steiner V, Becker K, Micheau O, Schneider P, Burns K, Tschopp J", "evidence": [ { "database": "UniProtKB", "id": "Q9ERH7", "url": "https://www.uniprot.org/uniprotkb/Q9ERH7" } ], "reference": [ { "type": "PubMed", "id": "11034606", "url": "https://glygen.org/publication/PubMed/11034606" } ] } ], "crossref": [ { "id": "Q9ERH7", "url": "https://www.uniprot.org/uniprotkb/Q9ERH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "11034606", "url": "https://glygen.org/publication/PubMed/11034606", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "VLQQVATALKKLKSLGLIHA", "down_seq": "LKPENIMLVDPVRQPYRVKV", "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "N", "comment": "Impairs catalytic activity and abolishes interaction with DAXX.", "evidence": [ { "database": "UniProtKB", "id": "Q9ERH7", "url": "https://www.uniprot.org/uniprotkb/Q9ERH7" }, { "database": "PubMed", "id": "11034606", "url": "https://glygen.org/publication/PubMed/11034606" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "226", "end_pos": "226" }, { "start_pos": "322", "end_pos": "322" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "359", "end_pos": "359" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9ERH7-1.359.359", "start_pos": 359, "end_pos": 359, "uniprot_canonical_ac": "Q9ERH7-1", "length": 1192, "uniprot_id": "HIPK3_MOUSE", "protein_name": "Homeodomain-interacting protein kinase 3", "refseq_ac": "NP_034564", "refseq_name": "homeodomain-interacting protein kinase 3 isoform 1", "gene_name": "Hipk3", "gene_names_uniprotkb": "Hipk3; Fist3", "gene_names_refseq": "DYRK6; FIST3; Hipk3; PKY; mir-1902", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ERH7", "url": "https://www.uniprot.org/uniprotkb/Q9ERH7" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain.", "journal": "Journal of proteome research", "date": "2008", "authors": "Ballif BA, Carey GR, Sunyaev SR, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9ERH7", "url": "https://www.uniprot.org/uniprotkb/Q9ERH7" }, { "database": "iPTMnet", "id": "Q9ERH7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ERH7" } ], "reference": [ { "type": "PubMed", "id": "18034455", "url": "https://glygen.org/publication/PubMed/18034455" } ] }, { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9ERH7", "url": "https://www.uniprot.org/uniprotkb/Q9ERH7" }, { "database": "iPTMnet", "id": "Q9ERH7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ERH7" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q9ERH7", "url": "https://www.uniprot.org/uniprotkb/Q9ERH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18034455", "url": "https://glygen.org/publication/PubMed/18034455", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9ERH7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ERH7", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "RVKVIDFGSASHVSKTVCST", "down_seq": "LQSRYYRAPEIILGLPFCEA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "Q9ERH7", "url": "https://www.uniprot.org/uniprotkb/Q9ERH7" }, { "database": "PubMed", "id": "18034455", "url": "https://glygen.org/publication/PubMed/18034455" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q9ERH7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ERH7" } ], "site_lbl": "Tyr359" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "226", "end_pos": "226" }, { "start_pos": "322", "end_pos": "322" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "359", "end_pos": "359" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P38647-1.198.198", "start_pos": 198, "end_pos": 198, "uniprot_canonical_ac": "P38647-1", "length": 679, "uniprot_id": "HSPA9_MOUSE", "protein_name": "Stress-70 protein, mitochondrial", "refseq_ac": "NP_034611", "refseq_name": "stress-70 protein, mitochondrial", "gene_name": "Hspa9", "gene_names_uniprotkb": "Hspa9; Grp75; Hsp74; Hspa9a", "gene_names_refseq": "74kDa; Csa; Grp75; Hsc74; Hsp74a; Hsp74; Hspa9a; Hspa9; Mortalin; Mot-2; Mot2; Mthsp70; Pbp74", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P38647", "url": "https://www.uniprot.org/uniprotkb/P38647" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "AENYLGHTAKNAVITVPAYF", "down_seq": "DSQRQATKDAGQISGLNVLR", "glycosylation": [ { "glytoucan_ac": "G35029YA", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "MKETAENYLGHTAKNAVITVPAYFNDSQR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn198", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "198", "end_pos": "198" }, { "start_pos": "461", "end_pos": "461" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "408", "end_pos": "408" }, { "start_pos": "87", "end_pos": "87" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P38647-1.461.461", "start_pos": 461, "end_pos": 461, "uniprot_canonical_ac": "P38647-1", "length": 679, "uniprot_id": "HSPA9_MOUSE", "protein_name": "Stress-70 protein, mitochondrial", "refseq_ac": "NP_034611", "refseq_name": "stress-70 protein, mitochondrial", "gene_name": "Hspa9", "gene_names_uniprotkb": "Hspa9; Grp75; Hsp74; Hspa9a", "gene_names_refseq": "74kDa; Csa; Grp75; Hsc74; Hsp74a; Hsp74; Hspa9a; Hspa9; Mortalin; Mot-2; Mot2; Mthsp70; Pbp74", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P38647", "url": "https://www.uniprot.org/uniprotkb/P38647" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "TPLSLGIETLGGVFTKLINR", "down_seq": "TTIPTKKSQVFSTAADGQTQ", "glycosylation": [ { "glytoucan_ac": "G89236MI", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "NTTIPTKKSQVFSTAADGQTQVEIK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn461", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "198", "end_pos": "198" }, { "start_pos": "461", "end_pos": "461" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "408", "end_pos": "408" }, { "start_pos": "87", "end_pos": "87" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P38647-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "P38647-1", "length": 679, "uniprot_id": "HSPA9_MOUSE", "protein_name": "Stress-70 protein, mitochondrial", "refseq_ac": "NP_034611", "refseq_name": "stress-70 protein, mitochondrial", "gene_name": "Hspa9", "gene_names_uniprotkb": "Hspa9; Grp75; Hsp74; Hspa9a", "gene_names_refseq": "74kDa; Csa; Grp75; Hsc74; Hsp74a; Hsp74; Hspa9a; Hspa9; Mortalin; Mot-2; Mot2; Mthsp70; Pbp74", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P38647", "url": "https://www.uniprot.org/uniprotkb/P38647" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Hepatocyte-specific O-GlcNAc transferase downregulation ameliorates nonalcoholic steatohepatitis by improving mitochondrial function.", "journal": "Molecular metabolism", "date": "2023-09", "authors": "Gonzalez-Rellan Maria J, Parracho Tamara, Heras Violeta, Rodriguez Amaia, Fondevila Marcos F, Novoa Eva, Lima Natalia, Varela-Rey Marta, Senra Ana, Chantada-Vazquez Maria D P, Ameneiro Cristina, Bernardo Ganeko, Fernandez-Ramos David, Lopitz-Otsoa Fernando, Bilbao Jon, Guallar Diana, Fidalgo Miguel, Bravo Susana, Dieguez Carlos, Martinez-Chantar Maria L, Millet Oscar, Mato Jose M, Schwaninger Markus, Prevot Vincent, Crespo Javier, Fr\u00fchbeck Gema, Iruzubieta Paula, Nogueiras Ruben", "evidence": [ { "database": "O-GlcNAc Database", "id": "P38647", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P38647" } ], "reference": [ { "type": "PubMed", "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647" } ] }, { "title": "O-GlcNAcylation is required for B cell homeostasis and antibody responses.", "journal": "Nature communications", "date": "2017", "authors": "Wu JL, Chiang MF, Hsu PH, Tsai DY, Hung KH, Wang YH, Angata T, Lin KI", "evidence": [ { "database": "O-GlcNAc Database", "id": "P38647", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P38647" } ], "reference": [ { "type": "PubMed", "id": "29187734", "url": "https://glygen.org/publication/PubMed/29187734" } ] }, { "title": "Differential Detection of O-GlcNAcylated proteins in the heart using antibodies.", "journal": "Analytical biochemistry", "date": "2023-10-01", "authors": "Narayanan Bhargavi, Zahra Fiddia, Reeves Russell A, Aggarwal Akanksha, O'Meally Robert N, Henry Roger K, Craven Megan, Jacobson Avital, Cole Robert N, Kohr Mark J, Umapathi Priya, Zachara Natasha E", "evidence": [ { "database": "O-GlcNAc Database", "id": "P38647", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P38647" } ], "reference": [ { "type": "PubMed", "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081" } ] }, { "title": "First comprehensive identification of cardiac proteins with putative increased O-GlcNAc levels during pressure overload hypertrophy.", "journal": "PloS one", "date": "2022", "authors": "Zhu Wei Zhong, Palazzo Teresa, Zhou Mowei, Ledee Dolena, Olson Heather M, Pa\u0161a-Toli\u0107 Ljiljana, Olson Aaron K", "evidence": [ { "database": "O-GlcNAc Database", "id": "P38647", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P38647" } ], "reference": [ { "type": "PubMed", "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343" } ] }, { "title": "Dynamic eIF3a O-GlcNAcylation controls translation reinitiation during nutrient stress.", "journal": "Nature chemical biology", "date": "2022", "authors": "Shu XE, Mao Y, Jia L, Qian SB", "evidence": [ { "database": "O-GlcNAc Database", "id": "P38647", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P38647" } ], "reference": [ { "type": "PubMed", "id": "34887587", "url": "https://glygen.org/publication/PubMed/34887587" } ] }, { "title": "A reference dataset of O-GlcNAc proteins in quadriceps skeletal muscle from mice.", "journal": "Glycobiology", "date": "2025-02-10", "authors": "Jaiswal Ruchi, Liu Yimin, Petriello Michael, Zhang Xiangmin, Yi Zhengping, Fehl Charlie", "evidence": [ { "database": "O-GlcNAc Database", "id": "P38647", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P38647" } ], "reference": [ { "type": "PubMed", "id": "39927985", "url": "https://glygen.org/publication/PubMed/39927985" } ] }, { "title": "Site-specific O-GlcNAcylation of Psme3 maintains mouse stem cell pluripotency by impairing P-body homeostasis.", "journal": "Cell reports", "date": "2021", "authors": "Pecori F, Kondo N, Ogura C, Miura T, Kume M, Minamijima Y, Yamamoto K, Nishihara S", "evidence": [ { "database": "O-GlcNAc Database", "id": "P38647", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P38647" } ], "reference": [ { "type": "PubMed", "id": "34260942", "url": "https://glygen.org/publication/PubMed/34260942" } ] }, { "title": "Dynamic O-GlcNAcylation governs long-range chromatin interactions in V(D)J recombination during early B-cell development.", "journal": "Cellular & molecular immunology", "date": "2025-01", "authors": "Jeon Bong Chan, Kim Yu-Ji, Park Ae Kyung, Song Mi-Ran, Na Ki Myeong, Lee Juwon, An Dasom, Park Yeseul, Hwang Heeyoun, Kim Tae-Don, Lim Junghyun, Park Sung-Kyun", "evidence": [ { "database": "O-GlcNAc Database", "id": "P38647", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P38647" } ], "reference": [ { "type": "PubMed", "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609" } ] }, { "title": "O-GlcNAcylation enhances CPS1 catalytic efficiency for ammonia and promotes ureagenesis.", "journal": "Nature communications", "date": "2022", "authors": "Soria LR, Makris G, D'Alessio AM, De Angelis A, Boffa I, Pravata VM, Rufenacht V, Attanasio S, Nusco E, Arena P, Ferenbach AT, Paris D, Cuomo P, Motta A, Nitzahn M, Lipshutz GS, Martinez-Pizarro A, Richard E, Desviat LR, Haberle J, van Aalten DMF, Brunetti-Pierri N", "evidence": [ { "database": "O-GlcNAc Database", "id": "P38647", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P38647" } ], "reference": [ { "type": "PubMed", "id": "36064721", "url": "https://glygen.org/publication/PubMed/36064721" } ] }, { "title": "O-GlcNAc regulates the mitochondrial integrated stress response by regulating ATF4.", "journal": "Frontiers in aging neuroscience", "date": "2023", "authors": "Alghusen Ibtihal M, Carman Marisa S, Wilkins Heather, Ephrame Sophiya John, Qiang Amy, Dias Wagner B, Fedosyuk Halyna, Denson Aspin R, Swerdlow Russell H, Slawson Chad", "evidence": [ { "database": "O-GlcNAc Database", "id": "P38647", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P38647" } ], "reference": [ { "type": "PubMed", "id": "38192280", "url": "https://glygen.org/publication/PubMed/38192280" } ] } ], "crossref": [ { "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P38647", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P38647", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "29187734", "url": "https://glygen.org/publication/PubMed/29187734", "database": "PubMed", "categories": [ "Other" ] }, { "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081", "database": "PubMed", "categories": [ "Other" ] }, { "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343", "database": "PubMed", "categories": [ "Other" ] }, { "id": "34887587", "url": "https://glygen.org/publication/PubMed/34887587", "database": "PubMed", "categories": [ "Other" ] }, { "id": "39927985", "url": "https://glygen.org/publication/PubMed/39927985", "database": "PubMed", "categories": [ "Other" ] }, { "id": "34260942", "url": "https://glygen.org/publication/PubMed/34260942", "database": "PubMed", "categories": [ "Other" ] }, { "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609", "database": "PubMed", "categories": [ "Other" ] }, { "id": "36064721", "url": "https://glygen.org/publication/PubMed/36064721", "database": "PubMed", "categories": [ "Other" ] }, { "id": "38192280", "url": "https://glygen.org/publication/PubMed/38192280", "database": "PubMed", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "37453647", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37453647" }, { "id": "P38647", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P38647" }, { "id": "29187734", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29187734" }, { "id": "37507081", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37507081" }, { "id": "36288343", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36288343" }, { "id": "34887587", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34887587" }, { "id": "39927985", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39927985" }, { "id": "34260942", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34260942" }, { "id": "39627609", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39627609" }, { "id": "36064721", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36064721" }, { "id": "38192280", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/38192280" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "198", "end_pos": "198" }, { "start_pos": "461", "end_pos": "461" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "408", "end_pos": "408" }, { "start_pos": "87", "end_pos": "87" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 10 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P38647-1.408.408", "start_pos": 408, "end_pos": 408, "uniprot_canonical_ac": "P38647-1", "length": 679, "uniprot_id": "HSPA9_MOUSE", "protein_name": "Stress-70 protein, mitochondrial", "refseq_ac": "NP_034611", "refseq_name": "stress-70 protein, mitochondrial", "gene_name": "Hspa9", "gene_names_uniprotkb": "Hspa9; Grp75; Hsp74; Hspa9a", "gene_names_refseq": "74kDa; Csa; Grp75; Hsc74; Hsp74a; Hsp74; Hspa9a; Hspa9; Mortalin; Mot-2; Mot2; Mthsp70; Pbp74", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P38647", "url": "https://www.uniprot.org/uniprotkb/P38647" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P38647", "url": "https://www.uniprot.org/uniprotkb/P38647", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GMTRMPKVQQTVQDLFGRAP", "down_seq": "KAVNPDEAVAIGAAIQGGVL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P38647", "url": "https://www.uniprot.org/uniprotkb/P38647" } ], "site_lbl": "Ser408" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "198", "end_pos": "198" }, { "start_pos": "461", "end_pos": "461" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "408", "end_pos": "408" }, { "start_pos": "87", "end_pos": "87" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P38647-1.87.87", "start_pos": 87, "end_pos": 87, "uniprot_canonical_ac": "P38647-1", "length": 679, "uniprot_id": "HSPA9_MOUSE", "protein_name": "Stress-70 protein, mitochondrial", "refseq_ac": "NP_034611", "refseq_name": "stress-70 protein, mitochondrial", "gene_name": "Hspa9", "gene_names_uniprotkb": "Hspa9; Grp75; Hsp74; Hspa9a", "gene_names_refseq": "74kDa; Csa; Grp75; Hsc74; Hsp74a; Hsp74; Hspa9a; Hspa9; Mortalin; Mot-2; Mot2; Mthsp70; Pbp74", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P38647", "url": "https://www.uniprot.org/uniprotkb/P38647" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P38647", "url": "https://www.uniprot.org/uniprotkb/P38647", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "VAVMEGKQAKVLENAEGART", "down_seq": "PSVVAFTADGERLVGMPAKR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P38647", "url": "https://www.uniprot.org/uniprotkb/P38647" } ], "site_lbl": "Thr87" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "198", "end_pos": "198" }, { "start_pos": "461", "end_pos": "461" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "408", "end_pos": "408" }, { "start_pos": "87", "end_pos": "87" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P63017-1.151.151", "start_pos": 151, "end_pos": 151, "uniprot_canonical_ac": "P63017-1", "length": 646, "uniprot_id": "HSP7C_MOUSE", "protein_name": "Heat shock cognate 71 kDa protein", "refseq_ac": "NP_112442", "refseq_name": "heat shock cognate 71 kDa protein isoform 1", "gene_name": "Hspa8", "gene_names_uniprotkb": "Hspa8; Hsc70; Hsc73", "gene_names_refseq": "2410008N15Rik; Hsc70; Hsc71; Hsc73; Hsp73; Hspa10; Hspa8", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P63017", "url": "https://www.uniprot.org/uniprotkb/P63017" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "AEAYLGKTVTNAVVTVPAYF", "down_seq": "DSQRQATKDAGTIAGLNVLR", "glycosylation": [ { "glytoucan_ac": "G02815KT", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "TVTNAVVTVPAYFNDSQR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn151", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "151", "end_pos": "151" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "417", "end_pos": "417" }, { "start_pos": "584", "end_pos": "584" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "153", "end_pos": "153" }, { "start_pos": "329", "end_pos": "329" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "541", "end_pos": "541" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P63017-1.153.153", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P63017-1.221.221", "start_pos": 221, "end_pos": 221, "uniprot_canonical_ac": "P63017-1", "length": 646, "uniprot_id": "HSP7C_MOUSE", "protein_name": "Heat shock cognate 71 kDa protein", "refseq_ac": "NP_112442", "refseq_name": "heat shock cognate 71 kDa protein isoform 1", "gene_name": "Hspa8", "gene_names_uniprotkb": "Hspa8; Hsc70; Hsc73", "gene_names_refseq": "2410008N15Rik; Hsc70; Hsc71; Hsc73; Hsp73; Hspa10; Hspa8", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P63017", "url": "https://www.uniprot.org/uniprotkb/P63017" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Hepatocyte-specific O-GlcNAc transferase downregulation ameliorates nonalcoholic steatohepatitis by improving mitochondrial function.", "journal": "Molecular metabolism", "date": "2023-09", "authors": "Gonzalez-Rellan Maria J, Parracho Tamara, Heras Violeta, Rodriguez Amaia, Fondevila Marcos F, Novoa Eva, Lima Natalia, Varela-Rey Marta, Senra Ana, Chantada-Vazquez Maria D P, Ameneiro Cristina, Bernardo Ganeko, Fernandez-Ramos David, Lopitz-Otsoa Fernando, Bilbao Jon, Guallar Diana, Fidalgo Miguel, Bravo Susana, Dieguez Carlos, Martinez-Chantar Maria L, Millet Oscar, Mato Jose M, Schwaninger Markus, Prevot Vincent, Crespo Javier, Fr\u00fchbeck Gema, Iruzubieta Paula, Nogueiras Ruben", "evidence": [ { "database": "O-GlcNAc Database", "id": "P63017", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P63017" } ], "reference": [ { "type": "PubMed", "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647" } ] }, { "title": "Differential Detection of O-GlcNAcylated proteins in the heart using antibodies.", "journal": "Analytical biochemistry", "date": "2023-10-01", "authors": "Narayanan Bhargavi, Zahra Fiddia, Reeves Russell A, Aggarwal Akanksha, O'Meally Robert N, Henry Roger K, Craven Megan, Jacobson Avital, Cole Robert N, Kohr Mark J, Umapathi Priya, Zachara Natasha E", "evidence": [ { "database": "O-GlcNAc Database", "id": "P63017", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P63017" } ], "reference": [ { "type": "PubMed", "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081" } ] }, { "title": "First comprehensive identification of cardiac proteins with putative increased O-GlcNAc levels during pressure overload hypertrophy.", "journal": "PloS one", "date": "2022", "authors": "Zhu Wei Zhong, Palazzo Teresa, Zhou Mowei, Ledee Dolena, Olson Heather M, Pa\u0161a-Toli\u0107 Ljiljana, Olson Aaron K", "evidence": [ { "database": "O-GlcNAc Database", "id": "P63017", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P63017" } ], "reference": [ { "type": "PubMed", "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343" } ] }, { "title": "Dynamic eIF3a O-GlcNAcylation controls translation reinitiation during nutrient stress.", "journal": "Nature chemical biology", "date": "2022", "authors": "Shu XE, Mao Y, Jia L, Qian SB", "evidence": [ { "database": "O-GlcNAc Database", "id": "P63017", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P63017" } ], "reference": [ { "type": "PubMed", "id": "34887587", "url": "https://glygen.org/publication/PubMed/34887587" } ] }, { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "P63017", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P63017" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] }, { "title": "A reference dataset of O-GlcNAc proteins in quadriceps skeletal muscle from mice.", "journal": "Glycobiology", "date": "2025-02-10", "authors": "Jaiswal Ruchi, Liu Yimin, Petriello Michael, Zhang Xiangmin, Yi Zhengping, Fehl Charlie", "evidence": [ { "database": "O-GlcNAc Database", "id": "P63017", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P63017" } ], "reference": [ { "type": "PubMed", "id": "39927985", "url": "https://glygen.org/publication/PubMed/39927985" } ] }, { "title": "Dynamic O-GlcNAcylation governs long-range chromatin interactions in V(D)J recombination during early B-cell development.", "journal": "Cellular & molecular immunology", "date": "2025-01", "authors": "Jeon Bong Chan, Kim Yu-Ji, Park Ae Kyung, Song Mi-Ran, Na Ki Myeong, Lee Juwon, An Dasom, Park Yeseul, Hwang Heeyoun, Kim Tae-Don, Lim Junghyun, Park Sung-Kyun", "evidence": [ { "database": "O-GlcNAc Database", "id": "P63017", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P63017" } ], "reference": [ { "type": "PubMed", "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "P63017", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P63017" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "O-GlcNAcylation site mapping by (azide-alkyne) click chemistry and mass spectrometry following intensive fractionation of skeletal muscle cells proteins.", "journal": "Journal of proteomics", "date": "2018", "authors": "Deracinois B, Camoin L, Lambert M, Boyer JB, Dupont E, Bastide B, Cieniewski-Bernard C", "evidence": [ { "database": "O-GlcNAc Database", "id": "P63017", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P63017" }, { "database": "O-GlcNAc Atlas", "id": "P63017", "url": "https://oglcnac.org/atlas/detail/P63017" } ], "reference": [ { "type": "PubMed", "id": "30016717", "url": "https://glygen.org/publication/PubMed/30016717" } ] } ], "crossref": [ { "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P63017", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P63017", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081", "database": "PubMed", "categories": [ "Other" ] }, { "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343", "database": "PubMed", "categories": [ "Other" ] }, { "id": "34887587", "url": "https://glygen.org/publication/PubMed/34887587", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "39927985", "url": "https://glygen.org/publication/PubMed/39927985", "database": "PubMed", "categories": [ "Other" ] }, { "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "30016717", "url": "https://glygen.org/publication/PubMed/30016717", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P63017", "url": "https://oglcnac.org/atlas/detail/P63017", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GGGTFDVSILTIEDGIFEVK", "down_seq": "TAGDTHLGGEDFDNRMVNHF", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser221", "evidence": [ { "id": "37453647", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37453647" }, { "id": "P63017", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P63017" }, { "id": "37507081", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37507081" }, { "id": "36288343", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36288343" }, { "id": "34887587", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34887587" }, { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" }, { "id": "39927985", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39927985" }, { "id": "39627609", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39627609" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "30016717", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30016717" }, { "id": "P63017", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P63017" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "151", "end_pos": "151" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "417", "end_pos": "417" }, { "start_pos": "584", "end_pos": "584" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "153", "end_pos": "153" }, { "start_pos": "329", "end_pos": "329" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "541", "end_pos": "541" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 9 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P63017-1.35.35", "start_pos": 35, "end_pos": 35, "uniprot_canonical_ac": "P63017-1", "length": 646, "uniprot_id": "HSP7C_MOUSE", "protein_name": "Heat shock cognate 71 kDa protein", "refseq_ac": "NP_112442", "refseq_name": "heat shock cognate 71 kDa protein isoform 1", "gene_name": "Hspa8", "gene_names_uniprotkb": "Hspa8; Hsc70; Hsc73", "gene_names_refseq": "2410008N15Rik; Hsc70; Hsc71; Hsc73; Hsp73; Hspa10; Hspa8", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P63017", "url": "https://www.uniprot.org/uniprotkb/P63017" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "YSCVGVFQHGKVEIIANDQG", "down_seq": "RTTPSYVAFTDTERLIGDAA", "glycosylation": [ { "glytoucan_ac": "G91707QI", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "VEIIANDQGNR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn35", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "151", "end_pos": "151" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "417", "end_pos": "417" }, { "start_pos": "584", "end_pos": "584" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "153", "end_pos": "153" }, { "start_pos": "329", "end_pos": "329" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "541", "end_pos": "541" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P63017-1.360.360", "start_pos": 360, "end_pos": 360, "uniprot_canonical_ac": "P63017-1", "length": 646, "uniprot_id": "HSP7C_MOUSE", "protein_name": "Heat shock cognate 71 kDa protein", "refseq_ac": "NP_112442", "refseq_name": "heat shock cognate 71 kDa protein isoform 1", "gene_name": "Hspa8", "gene_names_uniprotkb": "Hspa8; Hsc70; Hsc73", "gene_names_refseq": "2410008N15Rik; Hsc70; Hsc71; Hsc73; Hsp73; Hspa10; Hspa8", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P63017", "url": "https://www.uniprot.org/uniprotkb/P63017" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "STRIPKIQKLLQDFFNGKEL", "down_seq": "KSINPDEAVAYGAAVQAAIL", "glycosylation": [ { "glytoucan_ac": "G80160PH", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "LLQDFFNGKELNKSINPDEAVAYGAAVQAAILSGDK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn360", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "151", "end_pos": "151" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "417", "end_pos": "417" }, { "start_pos": "584", "end_pos": "584" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "153", "end_pos": "153" }, { "start_pos": "329", "end_pos": "329" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "541", "end_pos": "541" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P63017-1.362.362", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P63017-1.417.417", "start_pos": 417, "end_pos": 417, "uniprot_canonical_ac": "P63017-1", "length": 646, "uniprot_id": "HSP7C_MOUSE", "protein_name": "Heat shock cognate 71 kDa protein", "refseq_ac": "NP_112442", "refseq_name": "heat shock cognate 71 kDa protein isoform 1", "gene_name": "Hspa8", "gene_names_uniprotkb": "Hspa8; Hsc70; Hsc73", "gene_names_refseq": "2410008N15Rik; Hsc70; Hsc71; Hsc73; Hsp73; Hspa10; Hspa8", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P63017", "url": "https://www.uniprot.org/uniprotkb/P63017" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "TPLSLGIETAGGVMTVLIKR", "down_seq": "TTIPTKQTQTFTTYSDNQPG", "glycosylation": [ { "glytoucan_ac": "G62765YT", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "NTTIPTK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn417", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "151", "end_pos": "151" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "417", "end_pos": "417" }, { "start_pos": "584", "end_pos": "584" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "153", "end_pos": "153" }, { "start_pos": "329", "end_pos": "329" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "541", "end_pos": "541" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P63017-1.584.584", "start_pos": 584, "end_pos": 584, "uniprot_canonical_ac": "P63017-1", "length": 646, "uniprot_id": "HSP7C_MOUSE", "protein_name": "Heat shock cognate 71 kDa protein", "refseq_ac": "NP_112442", "refseq_name": "heat shock cognate 71 kDa protein isoform 1", "gene_name": "Hspa8", "gene_names_uniprotkb": "Hspa8; Hsc70; Hsc73", "gene_names_refseq": "2410008N15Rik; Hsc70; Hsc71; Hsc73; Hsp73; Hspa10; Hspa8", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P63017", "url": "https://www.uniprot.org/uniprotkb/P63017" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "DEDKQKILDKCNEIISWLDK", "down_seq": "QTAEKEEFEHQQKELEKVCN", "glycosylation": [ { "glytoucan_ac": "G71784JC", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "NQTAEKEEFEHQQK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn584", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "151", "end_pos": "151" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "417", "end_pos": "417" }, { "start_pos": "584", "end_pos": "584" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "153", "end_pos": "153" }, { "start_pos": "329", "end_pos": "329" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "541", "end_pos": "541" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P63017-1.153.153", "start_pos": 153, "end_pos": 153, "uniprot_canonical_ac": "P63017-1", "length": 646, "uniprot_id": "HSP7C_MOUSE", "protein_name": "Heat shock cognate 71 kDa protein", "refseq_ac": "NP_112442", "refseq_name": "heat shock cognate 71 kDa protein isoform 1", "gene_name": "Hspa8", "gene_names_uniprotkb": "Hspa8; Hsc70; Hsc73", "gene_names_refseq": "2410008N15Rik; Hsc70; Hsc71; Hsc73; Hsp73; Hspa10; Hspa8", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P63017", "url": "https://www.uniprot.org/uniprotkb/P63017" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P63017", "url": "https://www.uniprot.org/uniprotkb/P63017", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AYLGKTVTNAVVTVPAYFND", "down_seq": "QRQATKDAGTIAGLNVLRII", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P63017", "url": "https://www.uniprot.org/uniprotkb/P63017" } ], "site_lbl": "Ser153" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "151", "end_pos": "151" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "417", "end_pos": "417" }, { "start_pos": "584", "end_pos": "584" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "153", "end_pos": "153" }, { "start_pos": "329", "end_pos": "329" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "541", "end_pos": "541" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P63017-1.151.151", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P63017-1.329.329", "start_pos": 329, "end_pos": 329, "uniprot_canonical_ac": "P63017-1", "length": 646, "uniprot_id": "HSP7C_MOUSE", "protein_name": "Heat shock cognate 71 kDa protein", "refseq_ac": "NP_112442", "refseq_name": "heat shock cognate 71 kDa protein isoform 1", "gene_name": "Hspa8", "gene_names_uniprotkb": "Hspa8; Hsc70; Hsc73", "gene_names_refseq": "2410008N15Rik; Hsc70; Hsc71; Hsc73; Hsp73; Hspa10; Hspa8", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P63017", "url": "https://www.uniprot.org/uniprotkb/P63017" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P63017", "url": "https://www.uniprot.org/uniprotkb/P63017", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LFRGTLDPVEKALRDAKLDK", "down_seq": "QIHDIVLVGGSTRIPKIQKL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P63017", "url": "https://www.uniprot.org/uniprotkb/P63017" } ], "site_lbl": "Ser329" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "151", "end_pos": "151" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "417", "end_pos": "417" }, { "start_pos": "584", "end_pos": "584" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "153", "end_pos": "153" }, { "start_pos": "329", "end_pos": "329" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "541", "end_pos": "541" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P63017-1.362.362", "start_pos": 362, "end_pos": 362, "uniprot_canonical_ac": "P63017-1", "length": 646, "uniprot_id": "HSP7C_MOUSE", "protein_name": "Heat shock cognate 71 kDa protein", "refseq_ac": "NP_112442", "refseq_name": "heat shock cognate 71 kDa protein isoform 1", "gene_name": "Hspa8", "gene_names_uniprotkb": "Hspa8; Hsc70; Hsc73", "gene_names_refseq": "2410008N15Rik; Hsc70; Hsc71; Hsc73; Hsp73; Hspa10; Hspa8", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P63017", "url": "https://www.uniprot.org/uniprotkb/P63017" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P63017", "url": "https://www.uniprot.org/uniprotkb/P63017", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RIPKIQKLLQDFFNGKELNK", "down_seq": "INPDEAVAYGAAVQAAILSG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P63017", "url": "https://www.uniprot.org/uniprotkb/P63017" } ], "site_lbl": "Ser362" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "151", "end_pos": "151" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "417", "end_pos": "417" }, { "start_pos": "584", "end_pos": "584" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "153", "end_pos": "153" }, { "start_pos": "329", "end_pos": "329" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "541", "end_pos": "541" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P63017-1.360.360", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P63017-1.541.541", "start_pos": 541, "end_pos": 541, "uniprot_canonical_ac": "P63017-1", "length": 646, "uniprot_id": "HSP7C_MOUSE", "protein_name": "Heat shock cognate 71 kDa protein", "refseq_ac": "NP_112442", "refseq_name": "heat shock cognate 71 kDa protein isoform 1", "gene_name": "Hspa8", "gene_names_uniprotkb": "Hspa8; Hsc70; Hsc73", "gene_names_refseq": "2410008N15Rik; Hsc70; Hsc71; Hsc73; Hsp73; Hspa10; Hspa8", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P63017", "url": "https://www.uniprot.org/uniprotkb/P63017" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P63017", "url": "https://www.uniprot.org/uniprotkb/P63017", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EAEKYKAEDEKQRDKVSSKN", "down_seq": "LESYAFNMKATVEDEKLQGK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P63017", "url": "https://www.uniprot.org/uniprotkb/P63017" } ], "site_lbl": "Ser541" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "151", "end_pos": "151" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "360", "end_pos": "360" }, { "start_pos": "417", "end_pos": "417" }, { "start_pos": "584", "end_pos": "584" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "153", "end_pos": "153" }, { "start_pos": "329", "end_pos": "329" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "541", "end_pos": "541" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P70174-1.18.18", "start_pos": 18, "end_pos": 18, "uniprot_canonical_ac": "P70174-1", "length": 488, "uniprot_id": "HRH1_MOUSE", "protein_name": "Histamine H1 receptor", "refseq_ac": "NP_001239571", "refseq_name": "histamine H1 receptor", "gene_name": "Hrh1", "gene_names_uniprotkb": "Hrh1; Bphs", "gene_names_refseq": "Bphs; H1R; HH1R; Hir; Hrh1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P70174", "url": "https://www.uniprot.org/uniprotkb/P70174" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P70174", "url": "https://www.uniprot.org/uniprotkb/P70174", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "MSLPNTSSASEDKMCEG", "down_seq": "RTAMASPQLLPLVVVLSSIS", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn18", "evidence": [ { "id": "P70174", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P70174#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "18", "end_pos": "18" }, { "start_pos": "5", "end_pos": "5" } ] }, { "type": "snv", "site_list": [ { "start_pos": "20", "end_pos": "20" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "140", "end_pos": "140" }, { "start_pos": "142", "end_pos": "142" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "344", "end_pos": "344" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P70174-1.5.5", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P70174-1.20.20", "categories": [ "snv_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P70174-1.5.5", "start_pos": 5, "end_pos": 5, "uniprot_canonical_ac": "P70174-1", "length": 488, "uniprot_id": "HRH1_MOUSE", "protein_name": "Histamine H1 receptor", "refseq_ac": "NP_001239571", "refseq_name": "histamine H1 receptor", "gene_name": "Hrh1", "gene_names_uniprotkb": "Hrh1; Bphs", "gene_names_refseq": "Bphs; H1R; HH1R; Hir; Hrh1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P70174", "url": "https://www.uniprot.org/uniprotkb/P70174" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "P70174", "url": "https://www.uniprot.org/uniprotkb/P70174", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "MSLP", "down_seq": "TSSASEDKMCEGNRTAMASP", "glycosylation": [ { "glytoucan_ac": "G92275SC", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "MSLPNTSSASEDK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn5", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn5", "evidence": [ { "id": "P70174", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P70174#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "18", "end_pos": "18" }, { "start_pos": "5", "end_pos": "5" } ] }, { "type": "snv", "site_list": [ { "start_pos": "20", "end_pos": "20" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "140", "end_pos": "140" }, { "start_pos": "142", "end_pos": "142" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "344", "end_pos": "344" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "upstream", "id": "P70174-1.18.18", "categories": [ "glycosylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P70174-1.20.20", "categories": [ "snv_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P70174-1.20.20", "start_pos": 20, "end_pos": 20, "uniprot_canonical_ac": "P70174-1", "length": 488, "uniprot_id": "HRH1_MOUSE", "protein_name": "Histamine H1 receptor", "refseq_ac": "NP_001239571", "refseq_name": "histamine H1 receptor", "gene_name": "Hrh1", "gene_names_uniprotkb": "Hrh1; Bphs", "gene_names_refseq": "Bphs; H1R; HH1R; Hir; Hrh1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P70174", "url": "https://www.uniprot.org/uniprotkb/P70174" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388852351", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388852351", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "", "down_seq": "AMASPQLLPLVVVLSSISLV", "snv": [ { "evidence": [ { "id": "rs3388852351", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388852351" } ], "glycoeffect": [ "n-glyco-sequon-loss", "o-glyco-site-loss" ], "sequence_org": "T", "sequence_mut": "R", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-loss (NRT->NRR).", "chr_id": "6", "chr_pos": "114456779", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "T20", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "18", "end_pos": "18" }, { "start_pos": "5", "end_pos": "5" } ] }, { "type": "snv", "site_list": [ { "start_pos": "20", "end_pos": "20" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "140", "end_pos": "140" }, { "start_pos": "142", "end_pos": "142" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "344", "end_pos": "344" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P70174-1.5.5", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P70174-1.18.18", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P70174-1.140.140", "start_pos": 140, "end_pos": 140, "uniprot_canonical_ac": "P70174-1", "length": 488, "uniprot_id": "HRH1_MOUSE", "protein_name": "Histamine H1 receptor", "refseq_ac": "NP_001239571", "refseq_name": "histamine H1 receptor", "gene_name": "Hrh1", "gene_names_uniprotkb": "Hrh1; Bphs", "gene_names_refseq": "Bphs; H1R; HH1R; Hir; Hrh1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P70174", "url": "https://www.uniprot.org/uniprotkb/P70174" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P70174", "url": "https://www.uniprot.org/uniprotkb/P70174", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "ILCIDRYRSVQQPLRYLRYR", "down_seq": "KTRASATILGAWFLSFLWVI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P70174", "url": "https://www.uniprot.org/uniprotkb/P70174" } ], "site_lbl": "Thr140" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "18", "end_pos": "18" }, { "start_pos": "5", "end_pos": "5" } ] }, { "type": "snv", "site_list": [ { "start_pos": "20", "end_pos": "20" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "140", "end_pos": "140" }, { "start_pos": "142", "end_pos": "142" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "344", "end_pos": "344" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P70174-1.142.142", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P70174-1.142.142", "start_pos": 142, "end_pos": 142, "uniprot_canonical_ac": "P70174-1", "length": 488, "uniprot_id": "HRH1_MOUSE", "protein_name": "Histamine H1 receptor", "refseq_ac": "NP_001239571", "refseq_name": "histamine H1 receptor", "gene_name": "Hrh1", "gene_names_uniprotkb": "Hrh1; Bphs", "gene_names_refseq": "Bphs; H1R; HH1R; Hir; Hrh1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P70174", "url": "https://www.uniprot.org/uniprotkb/P70174" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P70174", "url": "https://www.uniprot.org/uniprotkb/P70174", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "CIDRYRSVQQPLRYLRYRTK", "down_seq": "RASATILGAWFLSFLWVIPI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P70174", "url": "https://www.uniprot.org/uniprotkb/P70174" } ], "site_lbl": "Thr142" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "18", "end_pos": "18" }, { "start_pos": "5", "end_pos": "5" } ] }, { "type": "snv", "site_list": [ { "start_pos": "20", "end_pos": "20" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "140", "end_pos": "140" }, { "start_pos": "142", "end_pos": "142" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "344", "end_pos": "344" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P70174-1.140.140", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P70174-1.230.230", "start_pos": 230, "end_pos": 230, "uniprot_canonical_ac": "P70174-1", "length": 488, "uniprot_id": "HRH1_MOUSE", "protein_name": "Histamine H1 receptor", "refseq_ac": "NP_001239571", "refseq_name": "histamine H1 receptor", "gene_name": "Hrh1", "gene_names_uniprotkb": "Hrh1; Bphs", "gene_names_refseq": "Bphs; H1R; HH1R; Hir; Hrh1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P70174", "url": "https://www.uniprot.org/uniprotkb/P70174" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P70174", "url": "https://www.uniprot.org/uniprotkb/P70174", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "YVKIYKAVRRHCQHRQLTNG", "down_seq": "LPTFLEIKLRSEDAKEGAKK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P70174", "url": "https://www.uniprot.org/uniprotkb/P70174" } ], "site_lbl": "Ser230" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "18", "end_pos": "18" }, { "start_pos": "5", "end_pos": "5" } ] }, { "type": "snv", "site_list": [ { "start_pos": "20", "end_pos": "20" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "140", "end_pos": "140" }, { "start_pos": "142", "end_pos": "142" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "344", "end_pos": "344" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P70174-1.344.344", "start_pos": 344, "end_pos": 344, "uniprot_canonical_ac": "P70174-1", "length": 488, "uniprot_id": "HRH1_MOUSE", "protein_name": "Histamine H1 receptor", "refseq_ac": "NP_001239571", "refseq_name": "histamine H1 receptor", "gene_name": "Hrh1", "gene_names_uniprotkb": "Hrh1; Bphs", "gene_names_refseq": "Bphs; H1R; HH1R; Hir; Hrh1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P70174", "url": "https://www.uniprot.org/uniprotkb/P70174" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P70174", "url": "https://www.uniprot.org/uniprotkb/P70174" }, { "database": "iPTMnet", "id": "P70174", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P70174" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "P70174", "url": "https://www.uniprot.org/uniprotkb/P70174", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P70174", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P70174", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DQTLSQPKMDEQSLSTCRRI", "down_seq": "ETSEDQTLVDRQSFSRTTDS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P70174", "url": "https://www.uniprot.org/uniprotkb/P70174" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "P70174", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P70174" } ], "site_lbl": "Ser344" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "18", "end_pos": "18" }, { "start_pos": "5", "end_pos": "5" } ] }, { "type": "snv", "site_list": [ { "start_pos": "20", "end_pos": "20" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "140", "end_pos": "140" }, { "start_pos": "142", "end_pos": "142" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "344", "end_pos": "344" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "P70174-1.347.347", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P70174-1.347.347", "start_pos": 347, "end_pos": 347, "uniprot_canonical_ac": "P70174-1", "length": 488, "uniprot_id": "HRH1_MOUSE", "protein_name": "Histamine H1 receptor", "refseq_ac": "NP_001239571", "refseq_name": "histamine H1 receptor", "gene_name": "Hrh1", "gene_names_uniprotkb": "Hrh1; Bphs", "gene_names_refseq": "Bphs; H1R; HH1R; Hir; Hrh1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P70174", "url": "https://www.uniprot.org/uniprotkb/P70174" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P70174", "url": "https://www.uniprot.org/uniprotkb/P70174" }, { "database": "iPTMnet", "id": "P70174", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P70174" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "P70174", "url": "https://www.uniprot.org/uniprotkb/P70174", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P70174", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P70174", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LSQPKMDEQSLSTCRRISET", "down_seq": "EDQTLVDRQSFSRTTDSDTS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P70174", "url": "https://www.uniprot.org/uniprotkb/P70174" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "P70174", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P70174" } ], "site_lbl": "Ser347" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "18", "end_pos": "18" }, { "start_pos": "5", "end_pos": "5" } ] }, { "type": "snv", "site_list": [ { "start_pos": "20", "end_pos": "20" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "140", "end_pos": "140" }, { "start_pos": "142", "end_pos": "142" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "344", "end_pos": "344" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "P70174-1.344.344", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P70174-1.381.381", "start_pos": 381, "end_pos": 381, "uniprot_canonical_ac": "P70174-1", "length": 488, "uniprot_id": "HRH1_MOUSE", "protein_name": "Histamine H1 receptor", "refseq_ac": "NP_001239571", "refseq_name": "histamine H1 receptor", "gene_name": "Hrh1", "gene_names_uniprotkb": "Hrh1; Bphs", "gene_names_refseq": "Bphs; H1R; HH1R; Hir; Hrh1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P70174", "url": "https://www.uniprot.org/uniprotkb/P70174" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P70174", "url": "https://www.uniprot.org/uniprotkb/P70174" }, { "database": "iPTMnet", "id": "P70174", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P70174" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "P70174", "url": "https://www.uniprot.org/uniprotkb/P70174", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P70174", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P70174", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TTDSDTSIEPGLGKVKARSR", "down_seq": "NSGLDYIKVTWKRLRSHSRQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P70174", "url": "https://www.uniprot.org/uniprotkb/P70174" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "P70174", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P70174" } ], "site_lbl": "Ser381" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "18", "end_pos": "18" }, { "start_pos": "5", "end_pos": "5" } ] }, { "type": "snv", "site_list": [ { "start_pos": "20", "end_pos": "20" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "140", "end_pos": "140" }, { "start_pos": "142", "end_pos": "142" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "344", "end_pos": "344" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P70174-1.383.383", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P70174-1.397.397", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P70174-1.399.399", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P70174-1.383.383", "start_pos": 383, "end_pos": 383, "uniprot_canonical_ac": "P70174-1", "length": 488, "uniprot_id": "HRH1_MOUSE", "protein_name": "Histamine H1 receptor", "refseq_ac": "NP_001239571", "refseq_name": "histamine H1 receptor", "gene_name": "Hrh1", "gene_names_uniprotkb": "Hrh1; Bphs", "gene_names_refseq": "Bphs; H1R; HH1R; Hir; Hrh1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P70174", "url": "https://www.uniprot.org/uniprotkb/P70174" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P70174", "url": "https://www.uniprot.org/uniprotkb/P70174" }, { "database": "iPTMnet", "id": "P70174", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P70174" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "P70174", "url": "https://www.uniprot.org/uniprotkb/P70174", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P70174", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P70174", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DSDTSIEPGLGKVKARSRSN", "down_seq": "GLDYIKVTWKRLRSHSRQYV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P70174", "url": "https://www.uniprot.org/uniprotkb/P70174" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "P70174", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P70174" } ], "site_lbl": "Ser383" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "18", "end_pos": "18" }, { "start_pos": "5", "end_pos": "5" } ] }, { "type": "snv", "site_list": [ { "start_pos": "20", "end_pos": "20" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "140", "end_pos": "140" }, { "start_pos": "142", "end_pos": "142" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "344", "end_pos": "344" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P70174-1.381.381", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P70174-1.397.397", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P70174-1.399.399", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P70174-1.397.397", "start_pos": 397, "end_pos": 397, "uniprot_canonical_ac": "P70174-1", "length": 488, "uniprot_id": "HRH1_MOUSE", "protein_name": "Histamine H1 receptor", "refseq_ac": "NP_001239571", "refseq_name": "histamine H1 receptor", "gene_name": "Hrh1", "gene_names_uniprotkb": "Hrh1; Bphs", "gene_names_refseq": "Bphs; H1R; HH1R; Hir; Hrh1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P70174", "url": "https://www.uniprot.org/uniprotkb/P70174" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P70174", "url": "https://www.uniprot.org/uniprotkb/P70174", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ARSRSNSGLDYIKVTWKRLR", "down_seq": "HSRQYVSGLHLNRERKAAKQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P70174", "url": "https://www.uniprot.org/uniprotkb/P70174" } ], "site_lbl": "Ser397" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "18", "end_pos": "18" }, { "start_pos": "5", "end_pos": "5" } ] }, { "type": "snv", "site_list": [ { "start_pos": "20", "end_pos": "20" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "140", "end_pos": "140" }, { "start_pos": "142", "end_pos": "142" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "344", "end_pos": "344" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P70174-1.381.381", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P70174-1.383.383", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P70174-1.399.399", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P70174-1.399.399", "start_pos": 399, "end_pos": 399, "uniprot_canonical_ac": "P70174-1", "length": 488, "uniprot_id": "HRH1_MOUSE", "protein_name": "Histamine H1 receptor", "refseq_ac": "NP_001239571", "refseq_name": "histamine H1 receptor", "gene_name": "Hrh1", "gene_names_uniprotkb": "Hrh1; Bphs", "gene_names_refseq": "Bphs; H1R; HH1R; Hir; Hrh1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P70174", "url": "https://www.uniprot.org/uniprotkb/P70174" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "PKC-dependent Phosphorylation of the H1 Histamine Receptor Modulates TRPC6 Activity.", "journal": "Cells", "date": "2014", "authors": "Chen X, Egly C, Riley AM, Li W, Tewson P, Hughes TE, Quinn AM, Obukhov AG", "evidence": [ { "database": "iPTMnet", "id": "P70174", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P70174" } ], "reference": [ { "type": "PubMed", "id": "24709960", "url": "https://glygen.org/publication/PubMed/24709960" } ] } ], "crossref": [ { "id": "P70174", "url": "https://www.uniprot.org/uniprotkb/P70174", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P70174", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P70174", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "24709960", "url": "https://glygen.org/publication/PubMed/24709960", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SRSNSGLDYIKVTWKRLRSH", "down_seq": "RQYVSGLHLNRERKAAKQLG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P70174", "url": "https://www.uniprot.org/uniprotkb/P70174" }, { "database": "iPTMnet", "id": "P70174", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P70174" }, { "database": "PubMed", "id": "24709960", "url": "https://glygen.org/publication/PubMed/24709960" } ], "site_lbl": "Ser399" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "18", "end_pos": "18" }, { "start_pos": "5", "end_pos": "5" } ] }, { "type": "snv", "site_list": [ { "start_pos": "20", "end_pos": "20" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "140", "end_pos": "140" }, { "start_pos": "142", "end_pos": "142" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "344", "end_pos": "344" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P70174-1.381.381", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "P70174-1.383.383", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P70174-1.397.397", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9CZJ2-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "Q9CZJ2-1", "length": 685, "uniprot_id": "HS12B_MOUSE", "protein_name": "Heat shock 70 kDa protein 12B", "refseq_ac": "NP_082582", "refseq_name": "heat shock 70 kDa protein 12B", "gene_name": "Hspa12b", "gene_names_uniprotkb": "Hspa12b", "gene_names_refseq": "2700081N06Rik; Hspa12b", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9CZJ2", "url": "https://www.uniprot.org/uniprotkb/Q9CZJ2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Differential Detection of O-GlcNAcylated proteins in the heart using antibodies.", "journal": "Analytical biochemistry", "date": "2023-10-01", "authors": "Narayanan Bhargavi, Zahra Fiddia, Reeves Russell A, Aggarwal Akanksha, O'Meally Robert N, Henry Roger K, Craven Megan, Jacobson Avital, Cole Robert N, Kohr Mark J, Umapathi Priya, Zachara Natasha E", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9CZJ2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9CZJ2" } ], "reference": [ { "type": "PubMed", "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081" } ] } ], "crossref": [ { "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9CZJ2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9CZJ2", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "37507081", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37507081" }, { "id": "Q9CZJ2", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9CZJ2" } ] } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "25", "end_pos": "25" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "46", "end_pos": "46" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9CZJ2-1.25.25", "start_pos": 25, "end_pos": 25, "uniprot_canonical_ac": "Q9CZJ2-1", "length": 685, "uniprot_id": "HS12B_MOUSE", "protein_name": "Heat shock 70 kDa protein 12B", "refseq_ac": "NP_082582", "refseq_name": "heat shock 70 kDa protein 12B", "gene_name": "Hspa12b", "gene_names_uniprotkb": "Hspa12b", "gene_names_refseq": "2700081N06Rik; Hspa12b", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9CZJ2", "url": "https://www.uniprot.org/uniprotkb/Q9CZJ2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9CZJ2", "url": "https://www.uniprot.org/uniprotkb/Q9CZJ2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PEMGLQGLYISSSPERSPVP", "down_seq": "PPGSPRTQESCGIAPLTPSQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9CZJ2", "url": "https://www.uniprot.org/uniprotkb/Q9CZJ2" } ], "site_lbl": "Ser25" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "25", "end_pos": "25" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "46", "end_pos": "46" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "Q9CZJ2-1.29.29", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "Q9CZJ2-1.42.42", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q9CZJ2-1.44.44", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9CZJ2-1.276.276", "start_pos": 276, "end_pos": 276, "uniprot_canonical_ac": "Q9CZJ2-1", "length": 685, "uniprot_id": "HS12B_MOUSE", "protein_name": "Heat shock 70 kDa protein 12B", "refseq_ac": "NP_082582", "refseq_name": "heat shock 70 kDa protein 12B", "gene_name": "Hspa12b", "gene_names_uniprotkb": "Hspa12b", "gene_names_refseq": "2700081N06Rik; Hspa12b", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9CZJ2", "url": "https://www.uniprot.org/uniprotkb/Q9CZJ2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9CZJ2", "url": "https://www.uniprot.org/uniprotkb/Q9CZJ2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "HQLMDLSSRTAGRGRLGERR", "down_seq": "IDSSFRHAREQLRRSRHSRT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9CZJ2", "url": "https://www.uniprot.org/uniprotkb/Q9CZJ2" } ], "site_lbl": "Ser276" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "25", "end_pos": "25" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "46", "end_pos": "46" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9CZJ2-1.29.29", "start_pos": 29, "end_pos": 29, "uniprot_canonical_ac": "Q9CZJ2-1", "length": 685, "uniprot_id": "HS12B_MOUSE", "protein_name": "Heat shock 70 kDa protein 12B", "refseq_ac": "NP_082582", "refseq_name": "heat shock 70 kDa protein 12B", "gene_name": "Hspa12b", "gene_names_uniprotkb": "Hspa12b", "gene_names_refseq": "2700081N06Rik; Hspa12b", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9CZJ2", "url": "https://www.uniprot.org/uniprotkb/Q9CZJ2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9CZJ2", "url": "https://www.uniprot.org/uniprotkb/Q9CZJ2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LQGLYISSSPERSPVPSPPG", "down_seq": "PRTQESCGIAPLTPSQSPKP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9CZJ2", "url": "https://www.uniprot.org/uniprotkb/Q9CZJ2" } ], "site_lbl": "Ser29" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "25", "end_pos": "25" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "46", "end_pos": "46" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "Q9CZJ2-1.25.25", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q9CZJ2-1.42.42", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q9CZJ2-1.44.44", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "Q9CZJ2-1.46.46", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9CZJ2-1.42.42", "start_pos": 42, "end_pos": 42, "uniprot_canonical_ac": "Q9CZJ2-1", "length": 685, "uniprot_id": "HS12B_MOUSE", "protein_name": "Heat shock 70 kDa protein 12B", "refseq_ac": "NP_082582", "refseq_name": "heat shock 70 kDa protein 12B", "gene_name": "Hspa12b", "gene_names_uniprotkb": "Hspa12b", "gene_names_refseq": "2700081N06Rik; Hspa12b", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9CZJ2", "url": "https://www.uniprot.org/uniprotkb/Q9CZJ2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9CZJ2", "url": "https://www.uniprot.org/uniprotkb/Q9CZJ2" }, { "database": "iPTMnet", "id": "Q9CZJ2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9CZJ2" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] }, { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9CZJ2", "url": "https://www.uniprot.org/uniprotkb/Q9CZJ2" }, { "database": "iPTMnet", "id": "Q9CZJ2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9CZJ2" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q9CZJ2", "url": "https://www.uniprot.org/uniprotkb/Q9CZJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9CZJ2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9CZJ2", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "PVPSPPGSPRTQESCGIAPL", "down_seq": "PSQSPKPEARALQQASFSVV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q9CZJ2", "url": "https://www.uniprot.org/uniprotkb/Q9CZJ2" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q9CZJ2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9CZJ2" } ], "site_lbl": "Thr42" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "25", "end_pos": "25" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "46", "end_pos": "46" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "Q9CZJ2-1.25.25", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "Q9CZJ2-1.29.29", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q9CZJ2-1.44.44", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q9CZJ2-1.46.46", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9CZJ2-1.44.44", "start_pos": 44, "end_pos": 44, "uniprot_canonical_ac": "Q9CZJ2-1", "length": 685, "uniprot_id": "HS12B_MOUSE", "protein_name": "Heat shock 70 kDa protein 12B", "refseq_ac": "NP_082582", "refseq_name": "heat shock 70 kDa protein 12B", "gene_name": "Hspa12b", "gene_names_uniprotkb": "Hspa12b", "gene_names_refseq": "2700081N06Rik; Hspa12b", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9CZJ2", "url": "https://www.uniprot.org/uniprotkb/Q9CZJ2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9CZJ2", "url": "https://www.uniprot.org/uniprotkb/Q9CZJ2" }, { "database": "iPTMnet", "id": "Q9CZJ2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9CZJ2" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q9CZJ2", "url": "https://www.uniprot.org/uniprotkb/Q9CZJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9CZJ2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9CZJ2", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PSPPGSPRTQESCGIAPLTP", "down_seq": "QSPKPEARALQQASFSVVVA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9CZJ2", "url": "https://www.uniprot.org/uniprotkb/Q9CZJ2" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q9CZJ2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9CZJ2" } ], "site_lbl": "Ser44" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "25", "end_pos": "25" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "46", "end_pos": "46" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "Q9CZJ2-1.25.25", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "Q9CZJ2-1.29.29", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q9CZJ2-1.42.42", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q9CZJ2-1.46.46", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9CZJ2-1.46.46", "start_pos": 46, "end_pos": 46, "uniprot_canonical_ac": "Q9CZJ2-1", "length": 685, "uniprot_id": "HS12B_MOUSE", "protein_name": "Heat shock 70 kDa protein 12B", "refseq_ac": "NP_082582", "refseq_name": "heat shock 70 kDa protein 12B", "gene_name": "Hspa12b", "gene_names_uniprotkb": "Hspa12b", "gene_names_refseq": "2700081N06Rik; Hspa12b", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9CZJ2", "url": "https://www.uniprot.org/uniprotkb/Q9CZJ2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9CZJ2", "url": "https://www.uniprot.org/uniprotkb/Q9CZJ2" }, { "database": "iPTMnet", "id": "Q9CZJ2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9CZJ2" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q9CZJ2", "url": "https://www.uniprot.org/uniprotkb/Q9CZJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9CZJ2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9CZJ2", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PPGSPRTQESCGIAPLTPSQ", "down_seq": "PKPEARALQQASFSVVVAID", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9CZJ2", "url": "https://www.uniprot.org/uniprotkb/Q9CZJ2" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q9CZJ2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9CZJ2" } ], "site_lbl": "Ser46" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "25", "end_pos": "25" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "46", "end_pos": "46" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "Q9CZJ2-1.29.29", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q9CZJ2-1.42.42", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q9CZJ2-1.44.44", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q3TBD2-1.875.875", "start_pos": 875, "end_pos": 875, "uniprot_canonical_ac": "Q3TBD2-1", "length": 1116, "uniprot_id": "HMHA1_MOUSE", "protein_name": "Rho GTPase-activating protein 45", "refseq_ac": "NP_001136173", "refseq_name": "rho GTPase-activating protein 45 isoform 1", "gene_name": "Arhgap45", "gene_names_uniprotkb": "Arhgap45; Hmha1", "gene_names_refseq": "6330406L22Rik; Arhgap45; Ha-1; Hmha1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation is required for B cell homeostasis and antibody responses.", "journal": "Nature communications", "date": "2017", "authors": "Wu JL, Chiang MF, Hsu PH, Tsai DY, Hung KH, Wang YH, Angata T, Lin KI", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q3TBD2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3TBD2" } ], "reference": [ { "type": "PubMed", "id": "29187734", "url": "https://glygen.org/publication/PubMed/29187734" } ] }, { "title": "Dynamic O-GlcNAcylation governs long-range chromatin interactions in V(D)J recombination during early B-cell development.", "journal": "Cellular & molecular immunology", "date": "2025-01", "authors": "Jeon Bong Chan, Kim Yu-Ji, Park Ae Kyung, Song Mi-Ran, Na Ki Myeong, Lee Juwon, An Dasom, Park Yeseul, Hwang Heeyoun, Kim Tae-Don, Lim Junghyun, Park Sung-Kyun", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q3TBD2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3TBD2" } ], "reference": [ { "type": "PubMed", "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609" } ] }, { "title": "O-GlcNAcylation Is Essential for Rapid Pomc Expression and Cell Proliferation in Corticotropic Tumor Cells.", "journal": "Endocrinology", "date": "2021", "authors": "Massman LJ, Pereckas M, Zwagerman NT, Olivier-Van Stichelen S", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q3TBD2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3TBD2" } ], "reference": [ { "type": "PubMed", "id": "34418053", "url": "https://glygen.org/publication/PubMed/34418053" } ] } ], "crossref": [ { "id": "29187734", "url": "https://glygen.org/publication/PubMed/29187734", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q3TBD2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3TBD2", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609", "database": "PubMed", "categories": [ "Other" ] }, { "id": "34418053", "url": "https://glygen.org/publication/PubMed/34418053", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KDSLKAEAEAKAASRGRQGG", "down_seq": "ESEAATLAMVGRLRELMQDL", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser875", "evidence": [ { "id": "29187734", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29187734" }, { "id": "Q3TBD2", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3TBD2" }, { "id": "39627609", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39627609" }, { "id": "34418053", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34418053" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "875", "end_pos": "875" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1035", "end_pos": "1035" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1017", "end_pos": "1017" }, { "start_pos": "1020", "end_pos": "1020" }, { "start_pos": "1022", "end_pos": "1022" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "568", "end_pos": "568" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "618", "end_pos": "618" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "92", "end_pos": "92" }, { "start_pos": "946", "end_pos": "946" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q3TBD2-1.1035.1035", "start_pos": 1035, "end_pos": 1035, "uniprot_canonical_ac": "Q3TBD2-1", "length": 1116, "uniprot_id": "HMHA1_MOUSE", "protein_name": "Rho GTPase-activating protein 45", "refseq_ac": "NP_001136173", "refseq_name": "rho GTPase-activating protein 45 isoform 1", "gene_name": "Arhgap45", "gene_names_uniprotkb": "Arhgap45; Hmha1", "gene_names_refseq": "6330406L22Rik; Arhgap45; Ha-1; Hmha1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3389079145", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389079145", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "AASNDSDSELEDASDPLSSS", "down_seq": "ASALHRLSFLEQTEAGLEEG", "snv": [ { "evidence": [ { "id": "rs3389079145", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389079145" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "D", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (DAS->NAS).", "chr_id": "10", "chr_pos": "79866634", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "D1035", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "875", "end_pos": "875" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1035", "end_pos": "1035" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1017", "end_pos": "1017" }, { "start_pos": "1020", "end_pos": "1020" }, { "start_pos": "1022", "end_pos": "1022" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "568", "end_pos": "568" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "618", "end_pos": "618" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "92", "end_pos": "92" }, { "start_pos": "946", "end_pos": "946" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "Q3TBD2-1.1017.1017", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "Q3TBD2-1.1020.1020", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "Q3TBD2-1.1022.1022", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q3TBD2-1.1017.1017", "start_pos": 1017, "end_pos": 1017, "uniprot_canonical_ac": "Q3TBD2-1", "length": 1116, "uniprot_id": "HMHA1_MOUSE", "protein_name": "Rho GTPase-activating protein 45", "refseq_ac": "NP_001136173", "refseq_name": "rho GTPase-activating protein 45 isoform 1", "gene_name": "Arhgap45", "gene_names_uniprotkb": "Arhgap45; Hmha1", "gene_names_refseq": "6330406L22Rik; Arhgap45; Ha-1; Hmha1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "The phagosomal proteome in interferon-gamma-activated macrophages.", "journal": "Immunity", "date": "2009", "authors": "Trost M, English L, Lemieux S, Courcelles M, Desjardins M, Thibault P", "evidence": [ { "database": "UniProtKB", "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2" }, { "database": "iPTMnet", "id": "Q3TBD2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3TBD2" } ], "reference": [ { "type": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" } ] }, { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2" }, { "database": "iPTMnet", "id": "Q3TBD2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3TBD2" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2" }, { "database": "iPTMnet", "id": "Q3TBD2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3TBD2" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] } ], "crossref": [ { "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q3TBD2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3TBD2", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GIVFPLQEEAEDGSRESHAA", "down_seq": "NDSDSELEDASDPLSSSDAS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2" }, { "database": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" }, { "database": "iPTMnet", "id": "Q3TBD2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3TBD2" } ], "site_lbl": "Ser1017" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "875", "end_pos": "875" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1035", "end_pos": "1035" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1017", "end_pos": "1017" }, { "start_pos": "1020", "end_pos": "1020" }, { "start_pos": "1022", "end_pos": "1022" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "568", "end_pos": "568" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "618", "end_pos": "618" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "92", "end_pos": "92" }, { "start_pos": "946", "end_pos": "946" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "Q3TBD2-1.1020.1020", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q3TBD2-1.1022.1022", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q3TBD2-1.1035.1035", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q3TBD2-1.1020.1020", "start_pos": 1020, "end_pos": 1020, "uniprot_canonical_ac": "Q3TBD2-1", "length": 1116, "uniprot_id": "HMHA1_MOUSE", "protein_name": "Rho GTPase-activating protein 45", "refseq_ac": "NP_001136173", "refseq_name": "rho GTPase-activating protein 45 isoform 1", "gene_name": "Arhgap45", "gene_names_uniprotkb": "Arhgap45; Hmha1", "gene_names_refseq": "6330406L22Rik; Arhgap45; Ha-1; Hmha1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2" }, { "database": "iPTMnet", "id": "Q3TBD2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3TBD2" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "title": "The phagosomal proteome in interferon-gamma-activated macrophages.", "journal": "Immunity", "date": "2009", "authors": "Trost M, English L, Lemieux S, Courcelles M, Desjardins M, Thibault P", "evidence": [ { "database": "UniProtKB", "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2" }, { "database": "iPTMnet", "id": "Q3TBD2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3TBD2" } ], "reference": [ { "type": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" } ] }, { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2" }, { "database": "iPTMnet", "id": "Q3TBD2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3TBD2" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] } ], "crossref": [ { "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q3TBD2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3TBD2", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "FPLQEEAEDGSRESHAASND", "down_seq": "DSELEDASDPLSSSDASALH", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" }, { "database": "iPTMnet", "id": "Q3TBD2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3TBD2" } ], "site_lbl": "Ser1020" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "875", "end_pos": "875" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1035", "end_pos": "1035" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1017", "end_pos": "1017" }, { "start_pos": "1020", "end_pos": "1020" }, { "start_pos": "1022", "end_pos": "1022" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "568", "end_pos": "568" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "618", "end_pos": "618" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "92", "end_pos": "92" }, { "start_pos": "946", "end_pos": "946" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "Q3TBD2-1.1017.1017", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q3TBD2-1.1022.1022", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q3TBD2-1.1035.1035", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q3TBD2-1.1022.1022", "start_pos": 1022, "end_pos": 1022, "uniprot_canonical_ac": "Q3TBD2-1", "length": 1116, "uniprot_id": "HMHA1_MOUSE", "protein_name": "Rho GTPase-activating protein 45", "refseq_ac": "NP_001136173", "refseq_name": "rho GTPase-activating protein 45 isoform 1", "gene_name": "Arhgap45", "gene_names_uniprotkb": "Arhgap45; Hmha1", "gene_names_refseq": "6330406L22Rik; Arhgap45; Ha-1; Hmha1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2" }, { "database": "iPTMnet", "id": "Q3TBD2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3TBD2" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] }, { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2" }, { "database": "iPTMnet", "id": "Q3TBD2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3TBD2" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "title": "The phagosomal proteome in interferon-gamma-activated macrophages.", "journal": "Immunity", "date": "2009", "authors": "Trost M, English L, Lemieux S, Courcelles M, Desjardins M, Thibault P", "evidence": [ { "database": "UniProtKB", "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2" }, { "database": "iPTMnet", "id": "Q3TBD2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3TBD2" } ], "reference": [ { "type": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" } ] } ], "crossref": [ { "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q3TBD2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3TBD2", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LQEEAEDGSRESHAASNDSD", "down_seq": "ELEDASDPLSSSDASALHRL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" }, { "database": "iPTMnet", "id": "Q3TBD2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3TBD2" } ], "site_lbl": "Ser1022" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "875", "end_pos": "875" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1035", "end_pos": "1035" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1017", "end_pos": "1017" }, { "start_pos": "1020", "end_pos": "1020" }, { "start_pos": "1022", "end_pos": "1022" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "568", "end_pos": "568" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "618", "end_pos": "618" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "92", "end_pos": "92" }, { "start_pos": "946", "end_pos": "946" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "Q3TBD2-1.1017.1017", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q3TBD2-1.1020.1020", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q3TBD2-1.1035.1035", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q3TBD2-1.23.23", "start_pos": 23, "end_pos": 23, "uniprot_canonical_ac": "Q3TBD2-1", "length": 1116, "uniprot_id": "HMHA1_MOUSE", "protein_name": "Rho GTPase-activating protein 45", "refseq_ac": "NP_001136173", "refseq_name": "rho GTPase-activating protein 45 isoform 1", "gene_name": "Arhgap45", "gene_names_uniprotkb": "Arhgap45; Hmha1", "gene_names_refseq": "6330406L22Rik; Arhgap45; Ha-1; Hmha1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2" }, { "database": "iPTMnet", "id": "Q3TBD2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3TBD2" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2" }, { "database": "iPTMnet", "id": "Q3TBD2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3TBD2" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] } ], "crossref": [ { "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q3TBD2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3TBD2", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SRKKRELMKTPSISKKNRAG", "down_seq": "PNPQSSSGELPRKDWTEAPG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" }, { "database": "iPTMnet", "id": "Q3TBD2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3TBD2" } ], "site_lbl": "Ser23" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "875", "end_pos": "875" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1035", "end_pos": "1035" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1017", "end_pos": "1017" }, { "start_pos": "1020", "end_pos": "1020" }, { "start_pos": "1022", "end_pos": "1022" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "568", "end_pos": "568" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "618", "end_pos": "618" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "92", "end_pos": "92" }, { "start_pos": "946", "end_pos": "946" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q3TBD2-1.568.568", "start_pos": 568, "end_pos": 568, "uniprot_canonical_ac": "Q3TBD2-1", "length": 1116, "uniprot_id": "HMHA1_MOUSE", "protein_name": "Rho GTPase-activating protein 45", "refseq_ac": "NP_001136173", "refseq_name": "rho GTPase-activating protein 45 isoform 1", "gene_name": "Arhgap45", "gene_names_uniprotkb": "Arhgap45; Hmha1", "gene_names_refseq": "6330406L22Rik; Arhgap45; Ha-1; Hmha1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2" }, { "database": "iPTMnet", "id": "Q3TBD2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3TBD2" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q3TBD2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3TBD2", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RGEEPDVRYDFEPYVSNNSW", "down_seq": "PIMRTRKGSFNPGDASGPEA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q3TBD2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3TBD2" } ], "site_lbl": "Ser568" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "875", "end_pos": "875" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1035", "end_pos": "1035" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1017", "end_pos": "1017" }, { "start_pos": "1020", "end_pos": "1020" }, { "start_pos": "1022", "end_pos": "1022" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "568", "end_pos": "568" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "618", "end_pos": "618" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "92", "end_pos": "92" }, { "start_pos": "946", "end_pos": "946" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "upstream", "id": "Q3TBD2-1.577.577", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q3TBD2-1.577.577", "start_pos": 577, "end_pos": 577, "uniprot_canonical_ac": "Q3TBD2-1", "length": 1116, "uniprot_id": "HMHA1_MOUSE", "protein_name": "Rho GTPase-activating protein 45", "refseq_ac": "NP_001136173", "refseq_name": "rho GTPase-activating protein 45 isoform 1", "gene_name": "Arhgap45", "gene_names_uniprotkb": "Arhgap45; Hmha1", "gene_names_refseq": "6330406L22Rik; Arhgap45; Ha-1; Hmha1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "The phagosomal proteome in interferon-gamma-activated macrophages.", "journal": "Immunity", "date": "2009", "authors": "Trost M, English L, Lemieux S, Courcelles M, Desjardins M, Thibault P", "evidence": [ { "database": "UniProtKB", "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2" }, { "database": "iPTMnet", "id": "Q3TBD2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3TBD2" } ], "reference": [ { "type": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" } ] }, { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2" }, { "database": "iPTMnet", "id": "Q3TBD2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3TBD2" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2" }, { "database": "iPTMnet", "id": "Q3TBD2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3TBD2" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] } ], "crossref": [ { "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q3TBD2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3TBD2", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DFEPYVSNNSWSPIMRTRKG", "down_seq": "FNPGDASGPEAAGSPPEEGG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2" }, { "database": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" }, { "database": "iPTMnet", "id": "Q3TBD2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3TBD2" } ], "site_lbl": "Ser577" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "875", "end_pos": "875" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1035", "end_pos": "1035" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1017", "end_pos": "1017" }, { "start_pos": "1020", "end_pos": "1020" }, { "start_pos": "1022", "end_pos": "1022" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "568", "end_pos": "568" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "618", "end_pos": "618" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "92", "end_pos": "92" }, { "start_pos": "946", "end_pos": "946" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "Q3TBD2-1.568.568", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q3TBD2-1.591.591", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q3TBD2-1.591.591", "start_pos": 591, "end_pos": 591, "uniprot_canonical_ac": "Q3TBD2-1", "length": 1116, "uniprot_id": "HMHA1_MOUSE", "protein_name": "Rho GTPase-activating protein 45", "refseq_ac": "NP_001136173", "refseq_name": "rho GTPase-activating protein 45 isoform 1", "gene_name": "Arhgap45", "gene_names_uniprotkb": "Arhgap45; Hmha1", "gene_names_refseq": "6330406L22Rik; Arhgap45; Ha-1; Hmha1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2" }, { "database": "iPTMnet", "id": "Q3TBD2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3TBD2" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q3TBD2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3TBD2", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MRTRKGSFNPGDASGPEAAG", "down_seq": "PPEEGGTSEAAPNKDHRGGR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q3TBD2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3TBD2" } ], "site_lbl": "Ser591" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "875", "end_pos": "875" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1035", "end_pos": "1035" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1017", "end_pos": "1017" }, { "start_pos": "1020", "end_pos": "1020" }, { "start_pos": "1022", "end_pos": "1022" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "568", "end_pos": "568" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "618", "end_pos": "618" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "92", "end_pos": "92" }, { "start_pos": "946", "end_pos": "946" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "Q3TBD2-1.577.577", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q3TBD2-1.618.618", "start_pos": 618, "end_pos": 618, "uniprot_canonical_ac": "Q3TBD2-1", "length": 1116, "uniprot_id": "HMHA1_MOUSE", "protein_name": "Rho GTPase-activating protein 45", "refseq_ac": "NP_001136173", "refseq_name": "rho GTPase-activating protein 45 isoform 1", "gene_name": "Arhgap45", "gene_names_uniprotkb": "Arhgap45; Hmha1", "gene_names_refseq": "6330406L22Rik; Arhgap45; Ha-1; Hmha1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2" }, { "database": "iPTMnet", "id": "Q3TBD2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3TBD2" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q3TBD2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3TBD2", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TSEAAPNKDHRGGRGHQVHK", "down_seq": "WPISISDTEVGLDTSSGDLK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q3TBD2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3TBD2" } ], "site_lbl": "Ser618" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "875", "end_pos": "875" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1035", "end_pos": "1035" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1017", "end_pos": "1017" }, { "start_pos": "1020", "end_pos": "1020" }, { "start_pos": "1022", "end_pos": "1022" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "568", "end_pos": "568" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "618", "end_pos": "618" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "92", "end_pos": "92" }, { "start_pos": "946", "end_pos": "946" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q3TBD2-1.72.72", "start_pos": 72, "end_pos": 72, "uniprot_canonical_ac": "Q3TBD2-1", "length": 1116, "uniprot_id": "HMHA1_MOUSE", "protein_name": "Rho GTPase-activating protein 45", "refseq_ac": "NP_001136173", "refseq_name": "rho GTPase-activating protein 45 isoform 1", "gene_name": "Arhgap45", "gene_names_uniprotkb": "Arhgap45; Hmha1", "gene_names_refseq": "6330406L22Rik; Arhgap45; Ha-1; Hmha1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "STVAKGTGTLKRPTSLSRHA", "down_seq": "AAGFPLSGTATWTLVRGYRS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2" } ], "site_lbl": "Ser72" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "875", "end_pos": "875" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1035", "end_pos": "1035" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1017", "end_pos": "1017" }, { "start_pos": "1020", "end_pos": "1020" }, { "start_pos": "1022", "end_pos": "1022" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "568", "end_pos": "568" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "618", "end_pos": "618" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "92", "end_pos": "92" }, { "start_pos": "946", "end_pos": "946" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "upstream", "id": "Q3TBD2-1.92.92", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q3TBD2-1.92.92", "start_pos": 92, "end_pos": 92, "uniprot_canonical_ac": "Q3TBD2-1", "length": 1116, "uniprot_id": "HMHA1_MOUSE", "protein_name": "Rho GTPase-activating protein 45", "refseq_ac": "NP_001136173", "refseq_name": "rho GTPase-activating protein 45 isoform 1", "gene_name": "Arhgap45", "gene_names_uniprotkb": "Arhgap45; Hmha1", "gene_names_refseq": "6330406L22Rik; Arhgap45; Ha-1; Hmha1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SAAGFPLSGTATWTLVRGYR", "down_seq": "PLSAASPAELPTEGAFPDGV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2" } ], "site_lbl": "Ser92" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "875", "end_pos": "875" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1035", "end_pos": "1035" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1017", "end_pos": "1017" }, { "start_pos": "1020", "end_pos": "1020" }, { "start_pos": "1022", "end_pos": "1022" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "568", "end_pos": "568" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "618", "end_pos": "618" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "92", "end_pos": "92" }, { "start_pos": "946", "end_pos": "946" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "Q3TBD2-1.72.72", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q3TBD2-1.98.98", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q3TBD2-1.946.946", "start_pos": 946, "end_pos": 946, "uniprot_canonical_ac": "Q3TBD2-1", "length": 1116, "uniprot_id": "HMHA1_MOUSE", "protein_name": "Rho GTPase-activating protein 45", "refseq_ac": "NP_001136173", "refseq_name": "rho GTPase-activating protein 45 isoform 1", "gene_name": "Arhgap45", "gene_names_uniprotkb": "Arhgap45; Hmha1", "gene_names_refseq": "6330406L22Rik; Arhgap45; Ha-1; Hmha1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NLGIVFGPTLLRPRPTDATV", "down_seq": "LSSLVDYPHQARVIETLIVH", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2" } ], "site_lbl": "Ser946" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "875", "end_pos": "875" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1035", "end_pos": "1035" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1017", "end_pos": "1017" }, { "start_pos": "1020", "end_pos": "1020" }, { "start_pos": "1022", "end_pos": "1022" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "568", "end_pos": "568" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "618", "end_pos": "618" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "92", "end_pos": "92" }, { "start_pos": "946", "end_pos": "946" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q3TBD2-1.98.98", "start_pos": 98, "end_pos": 98, "uniprot_canonical_ac": "Q3TBD2-1", "length": 1116, "uniprot_id": "HMHA1_MOUSE", "protein_name": "Rho GTPase-activating protein 45", "refseq_ac": "NP_001136173", "refseq_name": "rho GTPase-activating protein 45 isoform 1", "gene_name": "Arhgap45", "gene_names_uniprotkb": "Arhgap45; Hmha1", "gene_names_refseq": "6330406L22Rik; Arhgap45; Ha-1; Hmha1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LSGTATWTLVRGYRSPLSAA", "down_seq": "PAELPTEGAFPDGVEDISTL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3TBD2", "url": "https://www.uniprot.org/uniprotkb/Q3TBD2" } ], "site_lbl": "Ser98" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "875", "end_pos": "875" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1035", "end_pos": "1035" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1017", "end_pos": "1017" }, { "start_pos": "1020", "end_pos": "1020" }, { "start_pos": "1022", "end_pos": "1022" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "568", "end_pos": "568" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "618", "end_pos": "618" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "92", "end_pos": "92" }, { "start_pos": "946", "end_pos": "946" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "Q3TBD2-1.92.92", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q61699-1.280.280", "start_pos": 280, "end_pos": 280, "uniprot_canonical_ac": "Q61699-1", "length": 858, "uniprot_id": "HS105_MOUSE", "protein_name": "Heat shock protein 105 kDa", "refseq_ac": "NP_001334463", "refseq_name": "heat shock protein 105 kDa isoform 2", "gene_name": "Hsph1", "gene_names_uniprotkb": "Hsph1; Hsp105; Hsp110; Kiaa0201", "gene_names_refseq": "105kDa; Hsp105; Hsp110; Hsph1; hsp-E7I; hsp110/105", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q61699", "url": "https://www.uniprot.org/uniprotkb/Q61699" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "IRALLRLHQECEKLKKLMSS", "down_seq": "STDLPLNIECFMNDKDVSGK", "glycosylation": [ { "glytoucan_ac": "G72065MN", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "KLMSSNSTDLPLNIECFMNDK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn280", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "280", "end_pos": "280" }, { "start_pos": "466", "end_pos": "466" } ] }, { "type": "snv", "site_list": [ { "start_pos": "745", "end_pos": "745" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "509", "end_pos": "509" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "558", "end_pos": "558" }, { "start_pos": "562", "end_pos": "562" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "816", "end_pos": "816" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q61699-1.466.466", "start_pos": 466, "end_pos": 466, "uniprot_canonical_ac": "Q61699-1", "length": 858, "uniprot_id": "HS105_MOUSE", "protein_name": "Heat shock protein 105 kDa", "refseq_ac": "NP_001334463", "refseq_name": "heat shock protein 105 kDa isoform 2", "gene_name": "Hsph1", "gene_names_uniprotkb": "Hsph1; Hsp105; Hsp110; Kiaa0201", "gene_names_refseq": "105kDa; Hsp105; Hsp110; Hsph1; hsp-E7I; hsp110/105", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q61699", "url": "https://www.uniprot.org/uniprotkb/Q61699" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "YSDPQGVPYPEAKIGRFVVQ", "down_seq": "VSAQKDGEKSRVKVKVRVNT", "glycosylation": [ { "glytoucan_ac": "G80920RR", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "FVVQNVSAQK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn466", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "280", "end_pos": "280" }, { "start_pos": "466", "end_pos": "466" } ] }, { "type": "snv", "site_list": [ { "start_pos": "745", "end_pos": "745" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "509", "end_pos": "509" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "558", "end_pos": "558" }, { "start_pos": "562", "end_pos": "562" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "816", "end_pos": "816" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q61699-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "Q61699-1", "length": 858, "uniprot_id": "HS105_MOUSE", "protein_name": "Heat shock protein 105 kDa", "refseq_ac": "NP_001334463", "refseq_name": "heat shock protein 105 kDa isoform 2", "gene_name": "Hsph1", "gene_names_uniprotkb": "Hsph1; Hsp105; Hsp110; Kiaa0201", "gene_names_refseq": "105kDa; Hsp105; Hsp110; Hsph1; hsp-E7I; hsp110/105", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q61699", "url": "https://www.uniprot.org/uniprotkb/Q61699" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Hepatocyte-specific O-GlcNAc transferase downregulation ameliorates nonalcoholic steatohepatitis by improving mitochondrial function.", "journal": "Molecular metabolism", "date": "2023-09", "authors": "Gonzalez-Rellan Maria J, Parracho Tamara, Heras Violeta, Rodriguez Amaia, Fondevila Marcos F, Novoa Eva, Lima Natalia, Varela-Rey Marta, Senra Ana, Chantada-Vazquez Maria D P, Ameneiro Cristina, Bernardo Ganeko, Fernandez-Ramos David, Lopitz-Otsoa Fernando, Bilbao Jon, Guallar Diana, Fidalgo Miguel, Bravo Susana, Dieguez Carlos, Martinez-Chantar Maria L, Millet Oscar, Mato Jose M, Schwaninger Markus, Prevot Vincent, Crespo Javier, Fr\u00fchbeck Gema, Iruzubieta Paula, Nogueiras Ruben", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q61699", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q61699" } ], "reference": [ { "type": "PubMed", "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647" } ] }, { "title": "Differential Detection of O-GlcNAcylated proteins in the heart using antibodies.", "journal": "Analytical biochemistry", "date": "2023-10-01", "authors": "Narayanan Bhargavi, Zahra Fiddia, Reeves Russell A, Aggarwal Akanksha, O'Meally Robert N, Henry Roger K, Craven Megan, Jacobson Avital, Cole Robert N, Kohr Mark J, Umapathi Priya, Zachara Natasha E", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q61699", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q61699" } ], "reference": [ { "type": "PubMed", "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081" } ] }, { "title": "Dynamic O-GlcNAcylation governs long-range chromatin interactions in V(D)J recombination during early B-cell development.", "journal": "Cellular & molecular immunology", "date": "2025-01", "authors": "Jeon Bong Chan, Kim Yu-Ji, Park Ae Kyung, Song Mi-Ran, Na Ki Myeong, Lee Juwon, An Dasom, Park Yeseul, Hwang Heeyoun, Kim Tae-Don, Lim Junghyun, Park Sung-Kyun", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q61699", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q61699" } ], "reference": [ { "type": "PubMed", "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609" } ] }, { "title": "Dynamic eIF3a O-GlcNAcylation controls translation reinitiation during nutrient stress.", "journal": "Nature chemical biology", "date": "2022", "authors": "Shu XE, Mao Y, Jia L, Qian SB", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q61699", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q61699" } ], "reference": [ { "type": "PubMed", "id": "34887587", "url": "https://glygen.org/publication/PubMed/34887587" } ] } ], "crossref": [ { "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q61699", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q61699", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081", "database": "PubMed", "categories": [ "Other" ] }, { "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609", "database": "PubMed", "categories": [ "Other" ] }, { "id": "34887587", "url": "https://glygen.org/publication/PubMed/34887587", "database": "PubMed", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "37453647", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37453647" }, { "id": "Q61699", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q61699" }, { "id": "37507081", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37507081" }, { "id": "39627609", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39627609" }, { "id": "34887587", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34887587" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "280", "end_pos": "280" }, { "start_pos": "466", "end_pos": "466" } ] }, { "type": "snv", "site_list": [ { "start_pos": "745", "end_pos": "745" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "509", "end_pos": "509" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "558", "end_pos": "558" }, { "start_pos": "562", "end_pos": "562" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "816", "end_pos": "816" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q61699-1.745.745", "start_pos": 745, "end_pos": 745, "uniprot_canonical_ac": "Q61699-1", "length": 858, "uniprot_id": "HS105_MOUSE", "protein_name": "Heat shock protein 105 kDa", "refseq_ac": "NP_001334463", "refseq_name": "heat shock protein 105 kDa isoform 2", "gene_name": "Hsph1", "gene_names_uniprotkb": "Hsph1; Hsp105; Hsp110; Kiaa0201", "gene_names_refseq": "105kDa; Hsp105; Hsp110; Hsph1; hsp-E7I; hsp110/105", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q61699", "url": "https://www.uniprot.org/uniprotkb/Q61699" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388781492", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388781492", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "QHYAKIAADFRGKDEKYNHI", "down_seq": "ESEMKKVEKSVNEVMEWMNN", "snv": [ { "evidence": [ { "id": "rs3388781492", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388781492" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "D", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (DES->NES).", "chr_id": "5", "chr_pos": "149541992", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "D745", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "280", "end_pos": "280" }, { "start_pos": "466", "end_pos": "466" } ] }, { "type": "snv", "site_list": [ { "start_pos": "745", "end_pos": "745" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "509", "end_pos": "509" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "558", "end_pos": "558" }, { "start_pos": "562", "end_pos": "562" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "816", "end_pos": "816" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q61699-1.509.509", "start_pos": 509, "end_pos": 509, "uniprot_canonical_ac": "Q61699-1", "length": 858, "uniprot_id": "HS105_MOUSE", "protein_name": "Heat shock protein 105 kDa", "refseq_ac": "NP_001334463", "refseq_name": "heat shock protein 105 kDa isoform 2", "gene_name": "Hsph1", "gene_names_uniprotkb": "Hsph1; Hsp105; Hsp110; Kiaa0201", "gene_names_refseq": "105kDa; Hsp105; Hsp110; Hsph1; hsp-E7I; hsp110/105", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q61699", "url": "https://www.uniprot.org/uniprotkb/Q61699" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Protein kinase CK2 phosphorylates Hsp105 alpha at Ser509 and modulates its function.", "journal": "The Biochemical journal", "date": "2003", "authors": "Ishihara K, Yamagishi N, Hatayama T", "evidence": [ { "database": "UniProtKB", "id": "Q61699", "url": "https://www.uniprot.org/uniprotkb/Q61699" }, { "database": "iPTMnet", "id": "Q61699", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q61699" } ], "reference": [ { "type": "PubMed", "id": "12558502", "url": "https://glygen.org/publication/PubMed/12558502" } ] }, { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q61699", "url": "https://www.uniprot.org/uniprotkb/Q61699" }, { "database": "iPTMnet", "id": "Q61699", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q61699" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q61699", "url": "https://www.uniprot.org/uniprotkb/Q61699", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "12558502", "url": "https://glygen.org/publication/PubMed/12558502", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q61699", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q61699", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "IFTISTASMVEKVPTEEEDG", "down_seq": "SLEADMECPNQRPTESSDVD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q61699", "url": "https://www.uniprot.org/uniprotkb/Q61699" }, { "database": "PubMed", "id": "12558502", "url": "https://glygen.org/publication/PubMed/12558502" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q61699", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q61699" } ], "site_lbl": "Ser509" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "280", "end_pos": "280" }, { "start_pos": "466", "end_pos": "466" } ] }, { "type": "snv", "site_list": [ { "start_pos": "745", "end_pos": "745" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "509", "end_pos": "509" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "558", "end_pos": "558" }, { "start_pos": "562", "end_pos": "562" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "816", "end_pos": "816" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "Q61699-1.510.510", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q61699-1.510.510", "start_pos": 510, "end_pos": 510, "uniprot_canonical_ac": "Q61699-1", "length": 858, "uniprot_id": "HS105_MOUSE", "protein_name": "Heat shock protein 105 kDa", "refseq_ac": "NP_001334463", "refseq_name": "heat shock protein 105 kDa isoform 2", "gene_name": "Hsph1", "gene_names_uniprotkb": "Hsph1; Hsp105; Hsp110; Kiaa0201", "gene_names_refseq": "105kDa; Hsp105; Hsp110; Hsph1; hsp-E7I; hsp110/105", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q61699", "url": "https://www.uniprot.org/uniprotkb/Q61699" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q61699", "url": "https://www.uniprot.org/uniprotkb/Q61699" }, { "database": "iPTMnet", "id": "Q61699", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q61699" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q61699", "url": "https://www.uniprot.org/uniprotkb/Q61699", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q61699", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q61699", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "FTISTASMVEKVPTEEEDGS", "down_seq": "LEADMECPNQRPTESSDVDK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q61699", "url": "https://www.uniprot.org/uniprotkb/Q61699" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q61699", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q61699" } ], "site_lbl": "Ser510" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "280", "end_pos": "280" }, { "start_pos": "466", "end_pos": "466" } ] }, { "type": "snv", "site_list": [ { "start_pos": "745", "end_pos": "745" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "509", "end_pos": "509" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "558", "end_pos": "558" }, { "start_pos": "562", "end_pos": "562" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "816", "end_pos": "816" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "Q61699-1.509.509", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q61699-1.558.558", "start_pos": 558, "end_pos": 558, "uniprot_canonical_ac": "Q61699-1", "length": 858, "uniprot_id": "HS105_MOUSE", "protein_name": "Heat shock protein 105 kDa", "refseq_ac": "NP_001334463", "refseq_name": "heat shock protein 105 kDa isoform 2", "gene_name": "Hsph1", "gene_names_uniprotkb": "Hsph1; Hsp105; Hsp110; Kiaa0201", "gene_names_refseq": "105kDa; Hsp105; Hsp110; Hsph1; hsp-E7I; hsp110/105", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q61699", "url": "https://www.uniprot.org/uniprotkb/Q61699" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Phosphoproteomic analysis of the developing mouse brain.", "journal": "Molecular & cellular proteomics : MCP", "date": "2004", "authors": "Ballif BA, Villen J, Beausoleil SA, Schwartz D, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q61699", "url": "https://www.uniprot.org/uniprotkb/Q61699" }, { "database": "iPTMnet", "id": "Q61699", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q61699" } ], "reference": [ { "type": "PubMed", "id": "15345747", "url": "https://glygen.org/publication/PubMed/15345747" } ] } ], "crossref": [ { "id": "Q61699", "url": "https://www.uniprot.org/uniprotkb/Q61699", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "15345747", "url": "https://glygen.org/publication/PubMed/15345747", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q61699", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q61699", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EAGTQPQVQTDGQQTSQSPP", "down_seq": "PELTSEESKTPDADKANEKK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q61699", "url": "https://www.uniprot.org/uniprotkb/Q61699" }, { "database": "PubMed", "id": "15345747", "url": "https://glygen.org/publication/PubMed/15345747" }, { "database": "iPTMnet", "id": "Q61699", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q61699" } ], "site_lbl": "Ser558" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "280", "end_pos": "280" }, { "start_pos": "466", "end_pos": "466" } ] }, { "type": "snv", "site_list": [ { "start_pos": "745", "end_pos": "745" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "509", "end_pos": "509" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "558", "end_pos": "558" }, { "start_pos": "562", "end_pos": "562" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "816", "end_pos": "816" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "Q61699-1.562.562", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q61699-1.562.562", "start_pos": 562, "end_pos": 562, "uniprot_canonical_ac": "Q61699-1", "length": 858, "uniprot_id": "HS105_MOUSE", "protein_name": "Heat shock protein 105 kDa", "refseq_ac": "NP_001334463", "refseq_name": "heat shock protein 105 kDa isoform 2", "gene_name": "Hsph1", "gene_names_uniprotkb": "Hsph1; Hsp105; Hsp110; Kiaa0201", "gene_names_refseq": "105kDa; Hsp105; Hsp110; Hsph1; hsp-E7I; hsp110/105", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q61699", "url": "https://www.uniprot.org/uniprotkb/Q61699" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q61699", "url": "https://www.uniprot.org/uniprotkb/Q61699", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "QPQVQTDGQQTSQSPPSPEL", "down_seq": "SEESKTPDADKANEKKVDQP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q61699", "url": "https://www.uniprot.org/uniprotkb/Q61699" } ], "site_lbl": "Thr562" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "280", "end_pos": "280" }, { "start_pos": "466", "end_pos": "466" } ] }, { "type": "snv", "site_list": [ { "start_pos": "745", "end_pos": "745" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "509", "end_pos": "509" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "558", "end_pos": "558" }, { "start_pos": "562", "end_pos": "562" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "816", "end_pos": "816" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "Q61699-1.558.558", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q61699-1.810.810", "start_pos": 810, "end_pos": 810, "uniprot_canonical_ac": "Q61699-1", "length": 858, "uniprot_id": "HS105_MOUSE", "protein_name": "Heat shock protein 105 kDa", "refseq_ac": "NP_001334463", "refseq_name": "heat shock protein 105 kDa isoform 2", "gene_name": "Hsph1", "gene_names_uniprotkb": "Hsph1; Hsp105; Hsp110; Kiaa0201", "gene_names_refseq": "105kDa; Hsp105; Hsp110; Hsph1; hsp-E7I; hsp110/105", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q61699", "url": "https://www.uniprot.org/uniprotkb/Q61699" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.", "journal": "Molecular & cellular proteomics : MCP", "date": "2009", "authors": "Sweet SM, Bailey CM, Cunningham DL, Heath JK, Cooper HJ", "evidence": [ { "database": "UniProtKB", "id": "Q61699", "url": "https://www.uniprot.org/uniprotkb/Q61699" }, { "database": "iPTMnet", "id": "Q61699", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q61699" } ], "reference": [ { "type": "PubMed", "id": "19131326", "url": "https://glygen.org/publication/PubMed/19131326" } ] }, { "title": "The phagosomal proteome in interferon-gamma-activated macrophages.", "journal": "Immunity", "date": "2009", "authors": "Trost M, English L, Lemieux S, Courcelles M, Desjardins M, Thibault P", "evidence": [ { "database": "UniProtKB", "id": "Q61699", "url": "https://www.uniprot.org/uniprotkb/Q61699" }, { "database": "iPTMnet", "id": "Q61699", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q61699" } ], "reference": [ { "type": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" } ] } ], "crossref": [ { "id": "Q61699", "url": "https://www.uniprot.org/uniprotkb/Q61699", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19131326", "url": "https://glygen.org/publication/PubMed/19131326", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q61699", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q61699", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VKELNNVCEPVVTQPKPKIE", "down_seq": "PKLERTPNGPNIDKKEDLEG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q61699", "url": "https://www.uniprot.org/uniprotkb/Q61699" }, { "database": "PubMed", "id": "19131326", "url": "https://glygen.org/publication/PubMed/19131326" }, { "database": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" }, { "database": "iPTMnet", "id": "Q61699", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q61699" } ], "site_lbl": "Ser810" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "280", "end_pos": "280" }, { "start_pos": "466", "end_pos": "466" } ] }, { "type": "snv", "site_list": [ { "start_pos": "745", "end_pos": "745" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "509", "end_pos": "509" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "558", "end_pos": "558" }, { "start_pos": "562", "end_pos": "562" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "816", "end_pos": "816" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "upstream", "id": "Q61699-1.816.816", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q61699-1.816.816", "start_pos": 816, "end_pos": 816, "uniprot_canonical_ac": "Q61699-1", "length": 858, "uniprot_id": "HS105_MOUSE", "protein_name": "Heat shock protein 105 kDa", "refseq_ac": "NP_001334463", "refseq_name": "heat shock protein 105 kDa isoform 2", "gene_name": "Hsph1", "gene_names_uniprotkb": "Hsph1; Hsp105; Hsp110; Kiaa0201", "gene_names_refseq": "105kDa; Hsp105; Hsp110; Hsph1; hsp-E7I; hsp110/105", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q61699", "url": "https://www.uniprot.org/uniprotkb/Q61699" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q61699", "url": "https://www.uniprot.org/uniprotkb/Q61699", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "VCEPVVTQPKPKIESPKLER", "down_seq": "PNGPNIDKKEDLEGKNNLGA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q61699", "url": "https://www.uniprot.org/uniprotkb/Q61699" } ], "site_lbl": "Thr816" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "280", "end_pos": "280" }, { "start_pos": "466", "end_pos": "466" } ] }, { "type": "snv", "site_list": [ { "start_pos": "745", "end_pos": "745" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "509", "end_pos": "509" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "558", "end_pos": "558" }, { "start_pos": "562", "end_pos": "562" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "816", "end_pos": "816" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "Q61699-1.810.810", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q6EAL8-1.124.124", "start_pos": 124, "end_pos": 124, "uniprot_canonical_ac": "Q6EAL8-1", "length": 163, "uniprot_id": "IL31_MOUSE", "protein_name": "Interleukin-31", "refseq_ac": "NP_083870", "refseq_name": "interleukin-31 isoform 1 precursor", "gene_name": "Il31", "gene_names_uniprotkb": "Il31", "gene_names_refseq": "1700013B14Rik; Il31", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6EAL8", "url": "https://www.uniprot.org/uniprotkb/Q6EAL8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q6EAL8", "url": "https://www.uniprot.org/uniprotkb/Q6EAL8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "DTSWVIRWLTNISCFNPLNL", "down_seq": "ISVPGNTDESYDCKVFVLTV", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn124", "evidence": [ { "id": "Q6EAL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6EAL8#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "124", "end_pos": "124" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "84", "end_pos": "84" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q6EAL8-1.55.55", "start_pos": 55, "end_pos": 55, "uniprot_canonical_ac": "Q6EAL8-1", "length": 163, "uniprot_id": "IL31_MOUSE", "protein_name": "Interleukin-31", "refseq_ac": "NP_083870", "refseq_name": "interleukin-31 isoform 1 precursor", "gene_name": "Il31", "gene_names_uniprotkb": "Il31", "gene_names_refseq": "1700013B14Rik; Il31", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6EAL8", "url": "https://www.uniprot.org/uniprotkb/Q6EAL8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q6EAL8", "url": "https://www.uniprot.org/uniprotkb/Q6EAL8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "KEDLRTTIDLLKQESQDLYN", "down_seq": "YSIKQASGMSADESIQLPCF", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn55", "evidence": [ { "id": "Q6EAL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6EAL8#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "124", "end_pos": "124" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "84", "end_pos": "84" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q6EAL8-1.84.84", "start_pos": 84, "end_pos": 84, "uniprot_canonical_ac": "Q6EAL8-1", "length": 163, "uniprot_id": "IL31_MOUSE", "protein_name": "Interleukin-31", "refseq_ac": "NP_083870", "refseq_name": "interleukin-31 isoform 1 precursor", "gene_name": "Il31", "gene_names_uniprotkb": "Il31", "gene_names_refseq": "1700013B14Rik; Il31", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6EAL8", "url": "https://www.uniprot.org/uniprotkb/Q6EAL8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q6EAL8", "url": "https://www.uniprot.org/uniprotkb/Q6EAL8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "MSADESIQLPCFSLDREALT", "down_seq": "ISVIIAHLEKVKVLSENTVD", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn84", "evidence": [ { "id": "Q6EAL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6EAL8#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "124", "end_pos": "124" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "84", "end_pos": "84" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q91YJ5-1.688.688", "start_pos": 688, "end_pos": 688, "uniprot_canonical_ac": "Q91YJ5-1", "length": 727, "uniprot_id": "IF2M_MOUSE", "protein_name": "Translation initiation factor IF-2, mitochondrial", "refseq_ac": "NP_001269047", "refseq_name": "translation initiation factor IF-2, mitochondrial isoform 1 precursor", "gene_name": "Mtif2", "gene_names_uniprotkb": "Mtif2", "gene_names_refseq": "2310038D14Rik; 2410112O06Rik; IF-2(Mt); IF-2mt; IF2(mt); Mtif2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q91YJ5", "url": "https://www.uniprot.org/uniprotkb/Q91YJ5" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Phosphoproteome analysis of mouse liver using immobilized metal affinity purification and linear ion trap mass spectrometry.", "journal": "Rapid communications in mass spectrometry : RCM", "date": "2004", "authors": "Jin WH, Dai J, Zhou H, Xia QC, Zou HF, Zeng R", "evidence": [ { "database": "UniProtKB", "id": "Q91YJ5", "url": "https://www.uniprot.org/uniprotkb/Q91YJ5" }, { "database": "iPTMnet", "id": "Q91YJ5", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q91YJ5" } ], "reference": [ { "type": "PubMed", "id": "15378723", "url": "https://glygen.org/publication/PubMed/15378723" } ] } ], "crossref": [ { "id": "Q91YJ5", "url": "https://www.uniprot.org/uniprotkb/Q91YJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "15378723", "url": "https://glygen.org/publication/PubMed/15378723", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q91YJ5", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q91YJ5", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "IWKGSLTSLKHHKDDISVIK", "down_seq": "GMDCGLSLDEEKVEFKPGDQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q91YJ5", "url": "https://www.uniprot.org/uniprotkb/Q91YJ5" }, { "database": "PubMed", "id": "15378723", "url": "https://glygen.org/publication/PubMed/15378723" }, { "database": "iPTMnet", "id": "Q91YJ5", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q91YJ5" } ], "site_lbl": "Thr688" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "688", "end_pos": "688" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P50096-1.160.160", "start_pos": 160, "end_pos": 160, "uniprot_canonical_ac": "P50096-1", "length": 514, "uniprot_id": "IMDH1_MOUSE", "protein_name": "Inosine-5'-monophosphate dehydrogenase 1", "refseq_ac": "NP_001289862", "refseq_name": "inosine-5'-monophosphate dehydrogenase 1 isoform 1", "gene_name": "Impdh1", "gene_names_uniprotkb": "Impdh1; IMPDH", "gene_names_refseq": "B930086D20Rik; IMPDH-I; Impdh1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P50096", "url": "https://www.uniprot.org/uniprotkb/P50096" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P50096", "url": "https://www.uniprot.org/uniprotkb/P50096", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SGIPITATGTMGSKLVGIVT", "down_seq": "RDIDFLAEKDHTTLLSEVMT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P50096", "url": "https://www.uniprot.org/uniprotkb/P50096" } ], "site_lbl": "Ser160" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "160", "end_pos": "160" }, { "start_pos": "477", "end_pos": "477" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P50096-1.477.477", "start_pos": 477, "end_pos": 477, "uniprot_canonical_ac": "P50096-1", "length": 514, "uniprot_id": "IMDH1_MOUSE", "protein_name": "Inosine-5'-monophosphate dehydrogenase 1", "refseq_ac": "NP_001289862", "refseq_name": "inosine-5'-monophosphate dehydrogenase 1 isoform 1", "gene_name": "Impdh1", "gene_names_uniprotkb": "Impdh1; IMPDH", "gene_names_refseq": "B930086D20Rik; IMPDH-I; Impdh1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P50096", "url": "https://www.uniprot.org/uniprotkb/P50096" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Post-translational regulation of retinal IMPDH1 in vivo to adjust GTP synthesis to illumination conditions.", "journal": "eLife", "date": "2020", "authors": "Plana-Bonamaiso A, Lopez-Begines S, Fernandez-Justel D, Junza A, Soler-Tapia A, Andilla J, Loza-Alvarez P, Rosa JL, Miralles E, Casals I, Yanes O, de la Villa P, Buey RM, Mendez A", "evidence": [ { "database": "RefSeq", "id": "NP_001289862", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289862" }, { "database": "iPTMnet", "id": "P50096", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50096" } ], "reference": [ { "type": "PubMed", "id": "32254022", "url": "https://glygen.org/publication/PubMed/32254022" } ] } ], "crossref": [ { "id": "P50096", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50096", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "32254022", "url": "https://glygen.org/publication/PubMed/32254022", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VPYLIAGIQHGCQDIGAQSL", "down_seq": "VLRSMMYSGELKFEKRTMSA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P50096", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50096" }, { "database": "PubMed", "id": "32254022", "url": "https://glygen.org/publication/PubMed/32254022" } ], "site_lbl": "Ser477" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "160", "end_pos": "160" }, { "start_pos": "477", "end_pos": "477" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P70168-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "P70168-1", "length": 876, "uniprot_id": "IMB1_MOUSE", "protein_name": "Importin subunit beta-1", "refseq_ac": "NP_032405", "refseq_name": "importin subunit beta-1", "gene_name": "Kpnb1", "gene_names_uniprotkb": "Kpnb1; Impnb", "gene_names_refseq": "IPOB; Impnb; Kpnb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P70168", "url": "https://www.uniprot.org/uniprotkb/P70168" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Hepatocyte-specific O-GlcNAc transferase downregulation ameliorates nonalcoholic steatohepatitis by improving mitochondrial function.", "journal": "Molecular metabolism", "date": "2023-09", "authors": "Gonzalez-Rellan Maria J, Parracho Tamara, Heras Violeta, Rodriguez Amaia, Fondevila Marcos F, Novoa Eva, Lima Natalia, Varela-Rey Marta, Senra Ana, Chantada-Vazquez Maria D P, Ameneiro Cristina, Bernardo Ganeko, Fernandez-Ramos David, Lopitz-Otsoa Fernando, Bilbao Jon, Guallar Diana, Fidalgo Miguel, Bravo Susana, Dieguez Carlos, Martinez-Chantar Maria L, Millet Oscar, Mato Jose M, Schwaninger Markus, Prevot Vincent, Crespo Javier, Fr\u00fchbeck Gema, Iruzubieta Paula, Nogueiras Ruben", "evidence": [ { "database": "O-GlcNAc Database", "id": "P70168", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P70168" } ], "reference": [ { "type": "PubMed", "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647" } ] }, { "title": "First comprehensive identification of cardiac proteins with putative increased O-GlcNAc levels during pressure overload hypertrophy.", "journal": "PloS one", "date": "2022", "authors": "Zhu Wei Zhong, Palazzo Teresa, Zhou Mowei, Ledee Dolena, Olson Heather M, Pa\u0161a-Toli\u0107 Ljiljana, Olson Aaron K", "evidence": [ { "database": "O-GlcNAc Database", "id": "P70168", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P70168" } ], "reference": [ { "type": "PubMed", "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343" } ] }, { "title": "Dynamic eIF3a O-GlcNAcylation controls translation reinitiation during nutrient stress.", "journal": "Nature chemical biology", "date": "2022", "authors": "Shu XE, Mao Y, Jia L, Qian SB", "evidence": [ { "database": "O-GlcNAc Database", "id": "P70168", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P70168" } ], "reference": [ { "type": "PubMed", "id": "34887587", "url": "https://glygen.org/publication/PubMed/34887587" } ] }, { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "P70168", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P70168" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] }, { "title": "Dynamic O-GlcNAcylation governs long-range chromatin interactions in V(D)J recombination during early B-cell development.", "journal": "Cellular & molecular immunology", "date": "2025-01", "authors": "Jeon Bong Chan, Kim Yu-Ji, Park Ae Kyung, Song Mi-Ran, Na Ki Myeong, Lee Juwon, An Dasom, Park Yeseul, Hwang Heeyoun, Kim Tae-Don, Lim Junghyun, Park Sung-Kyun", "evidence": [ { "database": "O-GlcNAc Database", "id": "P70168", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P70168" } ], "reference": [ { "type": "PubMed", "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609" } ] } ], "crossref": [ { "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P70168", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P70168", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343", "database": "PubMed", "categories": [ "Other" ] }, { "id": "34887587", "url": "https://glygen.org/publication/PubMed/34887587", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609", "database": "PubMed", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "37453647", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37453647" }, { "id": "P70168", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P70168" }, { "id": "36288343", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36288343" }, { "id": "34887587", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34887587" }, { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" }, { "id": "39627609", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39627609" } ] } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "12", "end_pos": "12" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "upstream", "id": "P70168-1.12.12", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P70168-1.12.12", "start_pos": 12, "end_pos": 12, "uniprot_canonical_ac": "P70168-1", "length": 876, "uniprot_id": "IMB1_MOUSE", "protein_name": "Importin subunit beta-1", "refseq_ac": "NP_032405", "refseq_name": "importin subunit beta-1", "gene_name": "Kpnb1", "gene_names_uniprotkb": "Kpnb1; Impnb", "gene_names_refseq": "IPOB; Impnb; Kpnb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P70168", "url": "https://www.uniprot.org/uniprotkb/P70168" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P70168", "url": "https://www.uniprot.org/uniprotkb/P70168", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MELITILEKTV", "down_seq": "PDRLELEAAQKFLERAAVEN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P70168", "url": "https://www.uniprot.org/uniprotkb/P70168" } ], "site_lbl": "Ser12" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "12", "end_pos": "12" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "P70168-1.0.0", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q7TMY8-1.1095.1095", "start_pos": 1095, "end_pos": 1095, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "VGSPVRQRRSHHAASTTTAP", "down_seq": "PAARSTASALTKLLTKGLSW", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1095", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "Q7TMY8-1.1084.1084", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q7TMY8-1.2169.2169", "start_pos": 2169, "end_pos": 2169, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Quantitative Profiling of Protein O-GlcNAcylation Sites by an Isotope-Tagged Cleavable Linker.", "journal": "ACS chemical biology", "date": "2018", "authors": "Qin K, Zhu Y, Qin W, Gao J, Shao X, Wang YL, Zhou W, Wang C, Chen X", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q7TMY8", "url": "https://oglcnac.org/atlas/detail/Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "30059200", "url": "https://glygen.org/publication/PubMed/30059200" } ] } ], "crossref": [ { "id": "30059200", "url": "https://glygen.org/publication/PubMed/30059200", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q7TMY8", "url": "https://oglcnac.org/atlas/detail/Q7TMY8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QVALVNEVKAALGRALAMAE", "down_seq": "TEKHARLQAVMCIISTIMES", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser2169", "evidence": [ { "id": "30059200", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30059200" }, { "id": "Q7TMY8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q7TMY8" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q7TMY8-1.2619.2619", "start_pos": 2619, "end_pos": 2619, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "First comprehensive identification of cardiac proteins with putative increased O-GlcNAc levels during pressure overload hypertrophy.", "journal": "PloS one", "date": "2022", "authors": "Zhu Wei Zhong, Palazzo Teresa, Zhou Mowei, Ledee Dolena, Olson Heather M, Pa\u0161a-Toli\u0107 Ljiljana, Olson Aaron K", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q7TMY8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343" } ] }, { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q7TMY8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q7TMY8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8" }, { "database": "O-GlcNAc Atlas", "id": "Q7TMY8", "url": "https://oglcnac.org/atlas/detail/Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q7TMY8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Dynamic O-GlcNAcylation governs long-range chromatin interactions in V(D)J recombination during early B-cell development.", "journal": "Cellular & molecular immunology", "date": "2025-01", "authors": "Jeon Bong Chan, Kim Yu-Ji, Park Ae Kyung, Song Mi-Ran, Na Ki Myeong, Lee Juwon, An Dasom, Park Yeseul, Hwang Heeyoun, Kim Tae-Don, Lim Junghyun, Park Sung-Kyun", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q7TMY8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609" } ] }, { "title": "Profiling of Protein O-GlcNAcylation in Murine CD8(+) Effector- and Memory-like T Cells.", "journal": "ACS chemical biology", "date": "2017", "authors": "Lopez Aguilar A, Gao Y, Hou X, Lauvau G, Yates JR, Wu P", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q7TMY8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "29125738", "url": "https://glygen.org/publication/PubMed/29125738" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q7TMY8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] } ], "crossref": [ { "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q7TMY8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609", "database": "PubMed", "categories": [ "Other" ] }, { "id": "29125738", "url": "https://glygen.org/publication/PubMed/29125738", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q7TMY8", "url": "https://oglcnac.org/atlas/detail/Q7TMY8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QSRGRARLLVGNDDVHIIAR", "down_seq": "DDELLDDFFHDQSTATSQAG", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser2619", "evidence": [ { "id": "36288343", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36288343" }, { "id": "Q7TMY8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8" }, { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "39627609", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39627609" }, { "id": "29125738", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29125738" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "Q7TMY8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q7TMY8" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "site_lbl": "Ser2619" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "upstream", "id": "Q7TMY8-1.2632.2632", "categories": [ "glycosylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q7TMY8-1.2635.2635", "categories": [ "glycosylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "Q7TMY8-1.2636.2636", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 7 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q7TMY8-1.2632.2632", "start_pos": 2632, "end_pos": 2632, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "First comprehensive identification of cardiac proteins with putative increased O-GlcNAc levels during pressure overload hypertrophy.", "journal": "PloS one", "date": "2022", "authors": "Zhu Wei Zhong, Palazzo Teresa, Zhou Mowei, Ledee Dolena, Olson Heather M, Pa\u0161a-Toli\u0107 Ljiljana, Olson Aaron K", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q7TMY8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343" } ] }, { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q7TMY8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q7TMY8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8" }, { "database": "O-GlcNAc Atlas", "id": "Q7TMY8", "url": "https://oglcnac.org/atlas/detail/Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q7TMY8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Dynamic O-GlcNAcylation governs long-range chromatin interactions in V(D)J recombination during early B-cell development.", "journal": "Cellular & molecular immunology", "date": "2025-01", "authors": "Jeon Bong Chan, Kim Yu-Ji, Park Ae Kyung, Song Mi-Ran, Na Ki Myeong, Lee Juwon, An Dasom, Park Yeseul, Hwang Heeyoun, Kim Tae-Don, Lim Junghyun, Park Sung-Kyun", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q7TMY8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609" } ] }, { "title": "Profiling of Protein O-GlcNAcylation in Murine CD8(+) Effector- and Memory-like T Cells.", "journal": "ACS chemical biology", "date": "2017", "authors": "Lopez Aguilar A, Gao Y, Hou X, Lauvau G, Yates JR, Wu P", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q7TMY8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "29125738", "url": "https://glygen.org/publication/PubMed/29125738" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q7TMY8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] } ], "crossref": [ { "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q7TMY8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609", "database": "PubMed", "categories": [ "Other" ] }, { "id": "29125738", "url": "https://glygen.org/publication/PubMed/29125738", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DVHIIARSDDELLDDFFHDQ", "down_seq": "TATSQAGTLSSIPTALTRWT", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser2632", "evidence": [ { "id": "36288343", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36288343" }, { "id": "Q7TMY8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8" }, { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "39627609", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39627609" }, { "id": "29125738", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29125738" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "Q7TMY8-1.2619.2619", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q7TMY8-1.2635.2635", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q7TMY8-1.2636.2636", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 7 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q7TMY8-1.2635.2635", "start_pos": 2635, "end_pos": 2635, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Age-related loss of neural stem cell O-GlcNAc promotes a glial fate switch through STAT3 activation.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2020", "authors": "White CW 3rd, Fan X, Maynard JC, Wheatley EG, Bieri G, Couthouis J, Burlingame AL, Villeda SA", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q7TMY8", "url": "https://oglcnac.org/atlas/detail/Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054" } ] } ], "crossref": [ { "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q7TMY8", "url": "https://oglcnac.org/atlas/detail/Q7TMY8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "IIARSDDELLDDFFHDQSTA", "down_seq": "SQAGTLSSIPTALTRWTEEC", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2635", "evidence": [ { "id": "32848054", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32848054" }, { "id": "Q7TMY8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q7TMY8" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "Q7TMY8-1.2619.2619", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q7TMY8-1.2632.2632", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q7TMY8-1.2636.2636", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q7TMY8-1.2636.2636", "start_pos": 2636, "end_pos": 2636, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "First comprehensive identification of cardiac proteins with putative increased O-GlcNAc levels during pressure overload hypertrophy.", "journal": "PloS one", "date": "2022", "authors": "Zhu Wei Zhong, Palazzo Teresa, Zhou Mowei, Ledee Dolena, Olson Heather M, Pa\u0161a-Toli\u0107 Ljiljana, Olson Aaron K", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q7TMY8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343" } ] }, { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q7TMY8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q7TMY8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8" }, { "database": "O-GlcNAc Atlas", "id": "Q7TMY8", "url": "https://oglcnac.org/atlas/detail/Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q7TMY8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Dynamic O-GlcNAcylation governs long-range chromatin interactions in V(D)J recombination during early B-cell development.", "journal": "Cellular & molecular immunology", "date": "2025-01", "authors": "Jeon Bong Chan, Kim Yu-Ji, Park Ae Kyung, Song Mi-Ran, Na Ki Myeong, Lee Juwon, An Dasom, Park Yeseul, Hwang Heeyoun, Kim Tae-Don, Lim Junghyun, Park Sung-Kyun", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q7TMY8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609" } ] }, { "title": "Profiling of Protein O-GlcNAcylation in Murine CD8(+) Effector- and Memory-like T Cells.", "journal": "ACS chemical biology", "date": "2017", "authors": "Lopez Aguilar A, Gao Y, Hou X, Lauvau G, Yates JR, Wu P", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q7TMY8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "29125738", "url": "https://glygen.org/publication/PubMed/29125738" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q7TMY8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Age-related loss of neural stem cell O-GlcNAc promotes a glial fate switch through STAT3 activation.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2020", "authors": "White CW 3rd, Fan X, Maynard JC, Wheatley EG, Bieri G, Couthouis J, Burlingame AL, Villeda SA", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q7TMY8", "url": "https://oglcnac.org/atlas/detail/Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054" } ] } ], "crossref": [ { "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q7TMY8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609", "database": "PubMed", "categories": [ "Other" ] }, { "id": "29125738", "url": "https://glygen.org/publication/PubMed/29125738", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q7TMY8", "url": "https://oglcnac.org/atlas/detail/Q7TMY8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "IARSDDELLDDFFHDQSTAT", "down_seq": "QAGTLSSIPTALTRWTEECK", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser2636", "evidence": [ { "id": "36288343", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36288343" }, { "id": "Q7TMY8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8" }, { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "39627609", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39627609" }, { "id": "29125738", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29125738" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "32848054", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32848054" }, { "id": "Q7TMY8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q7TMY8" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "Q7TMY8-1.2619.2619", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q7TMY8-1.2632.2632", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q7TMY8-1.2635.2635", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q7TMY8-1.2747.2747", "start_pos": 2747, "end_pos": 2747, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "NDSTEQNVSDGTPMPDSYPT", "down_seq": "PSSTDAPTSESKETLGTLQP", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2747", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "Q7TMY8-1.2751.2751", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q7TMY8-1.2874.2874", "start_pos": 2874, "end_pos": 2874, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "GSPMDTSSLASCTLEEAVGD", "down_seq": "PAAGSSEQPTAGSSTPGDAP", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2874", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "Q7TMY8-1.2861.2861", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q7TMY8-1.2887.2887", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q7TMY8-1.2888.2888", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q7TMY8-1.2889.2889", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q7TMY8-1.2889.2889", "start_pos": 2889, "end_pos": 2889, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "EAVGDTPAAGSSEQPTAGSS", "down_seq": "PGDAPSVVAEVQGRPDVSRE", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2889", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "site_lbl": "Thr2889" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "Q7TMY8-1.2874.2874", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q7TMY8-1.2887.2887", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q7TMY8-1.2888.2888", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q7TMY8-1.3116.3116", "start_pos": 3116, "end_pos": 3116, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Cytosolic N-GlcNAc proteins are formed by the action of endo-beta-N-acetylglucosaminidase.", "journal": "Biochemical and biophysical research communications", "date": "2020", "authors": "Maynard JC, Fujihira H, Dolgonos GE, Suzuki T, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q7TMY8", "url": "https://oglcnac.org/atlas/detail/Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141" } ] } ], "crossref": [ { "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q7TMY8", "url": "https://oglcnac.org/atlas/detail/Q7TMY8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LRREQEARQRQLMHERLFGH", "down_seq": "STSALSAILRSPAFTSRLSG", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser3116", "evidence": [ { "id": "32782141", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32782141" }, { "id": "Q7TMY8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q7TMY8" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "site_lbl": "Ser3116" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "Q7TMY8-1.3117.3117", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q7TMY8-1.3118.3118", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q7TMY8-1.3122.3122", "categories": [ "glycosylation_flag", "snv_flag", "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q7TMY8-1.3127.3127", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q7TMY8-1.3135.3135", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q7TMY8-1.3117.3117", "start_pos": 3117, "end_pos": 3117, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Cytosolic N-GlcNAc proteins are formed by the action of endo-beta-N-acetylglucosaminidase.", "journal": "Biochemical and biophysical research communications", "date": "2020", "authors": "Maynard JC, Fujihira H, Dolgonos GE, Suzuki T, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q7TMY8", "url": "https://oglcnac.org/atlas/detail/Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141" } ] } ], "crossref": [ { "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q7TMY8", "url": "https://oglcnac.org/atlas/detail/Q7TMY8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RREQEARQRQLMHERLFGHS", "down_seq": "TSALSAILRSPAFTSRLSGN", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser3117", "evidence": [ { "id": "32782141", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32782141" }, { "id": "Q7TMY8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q7TMY8" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "site_lbl": "Ser3117" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "Q7TMY8-1.3116.3116", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q7TMY8-1.3118.3118", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q7TMY8-1.3122.3122", "categories": [ "glycosylation_flag", "snv_flag", "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q7TMY8-1.3127.3127", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q7TMY8-1.3135.3135", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q7TMY8-1.3118.3118", "start_pos": 3118, "end_pos": 3118, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "First comprehensive identification of cardiac proteins with putative increased O-GlcNAc levels during pressure overload hypertrophy.", "journal": "PloS one", "date": "2022", "authors": "Zhu Wei Zhong, Palazzo Teresa, Zhou Mowei, Ledee Dolena, Olson Heather M, Pa\u0161a-Toli\u0107 Ljiljana, Olson Aaron K", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q7TMY8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343" } ] }, { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q7TMY8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q7TMY8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8" }, { "database": "O-GlcNAc Atlas", "id": "Q7TMY8", "url": "https://oglcnac.org/atlas/detail/Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q7TMY8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Dynamic O-GlcNAcylation governs long-range chromatin interactions in V(D)J recombination during early B-cell development.", "journal": "Cellular & molecular immunology", "date": "2025-01", "authors": "Jeon Bong Chan, Kim Yu-Ji, Park Ae Kyung, Song Mi-Ran, Na Ki Myeong, Lee Juwon, An Dasom, Park Yeseul, Hwang Heeyoun, Kim Tae-Don, Lim Junghyun, Park Sung-Kyun", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q7TMY8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609" } ] }, { "title": "Profiling of Protein O-GlcNAcylation in Murine CD8(+) Effector- and Memory-like T Cells.", "journal": "ACS chemical biology", "date": "2017", "authors": "Lopez Aguilar A, Gao Y, Hou X, Lauvau G, Yates JR, Wu P", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q7TMY8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "29125738", "url": "https://glygen.org/publication/PubMed/29125738" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q7TMY8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Cytosolic N-GlcNAc proteins are formed by the action of endo-beta-N-acetylglucosaminidase.", "journal": "Biochemical and biophysical research communications", "date": "2020", "authors": "Maynard JC, Fujihira H, Dolgonos GE, Suzuki T, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q7TMY8", "url": "https://oglcnac.org/atlas/detail/Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141" } ] } ], "crossref": [ { "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q7TMY8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609", "database": "PubMed", "categories": [ "Other" ] }, { "id": "29125738", "url": "https://glygen.org/publication/PubMed/29125738", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q7TMY8", "url": "https://oglcnac.org/atlas/detail/Q7TMY8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "REQEARQRQLMHERLFGHSS", "down_seq": "SALSAILRSPAFTSRLSGNR", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3118", "evidence": [ { "id": "36288343", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36288343" }, { "id": "Q7TMY8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8" }, { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "39627609", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39627609" }, { "id": "29125738", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29125738" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "32782141", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32782141" }, { "id": "Q7TMY8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q7TMY8" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "Q7TMY8-1.3116.3116", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q7TMY8-1.3117.3117", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q7TMY8-1.3122.3122", "categories": [ "glycosylation_flag", "snv_flag", "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q7TMY8-1.3127.3127", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "Q7TMY8-1.3135.3135", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q7TMY8-1.3122.3122", "start_pos": 3122, "end_pos": 3122, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "First comprehensive identification of cardiac proteins with putative increased O-GlcNAc levels during pressure overload hypertrophy.", "journal": "PloS one", "date": "2022", "authors": "Zhu Wei Zhong, Palazzo Teresa, Zhou Mowei, Ledee Dolena, Olson Heather M, Pa\u0161a-Toli\u0107 Ljiljana, Olson Aaron K", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q7TMY8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343" } ] }, { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q7TMY8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q7TMY8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8" }, { "database": "O-GlcNAc Atlas", "id": "Q7TMY8", "url": "https://oglcnac.org/atlas/detail/Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q7TMY8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Dynamic O-GlcNAcylation governs long-range chromatin interactions in V(D)J recombination during early B-cell development.", "journal": "Cellular & molecular immunology", "date": "2025-01", "authors": "Jeon Bong Chan, Kim Yu-Ji, Park Ae Kyung, Song Mi-Ran, Na Ki Myeong, Lee Juwon, An Dasom, Park Yeseul, Hwang Heeyoun, Kim Tae-Don, Lim Junghyun, Park Sung-Kyun", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q7TMY8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609" } ] }, { "title": "Profiling of Protein O-GlcNAcylation in Murine CD8(+) Effector- and Memory-like T Cells.", "journal": "ACS chemical biology", "date": "2017", "authors": "Lopez Aguilar A, Gao Y, Hou X, Lauvau G, Yates JR, Wu P", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q7TMY8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "29125738", "url": "https://glygen.org/publication/PubMed/29125738" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q7TMY8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] } ], "crossref": [ { "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q7TMY8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609", "database": "PubMed", "categories": [ "Other" ] }, { "id": "29125738", "url": "https://glygen.org/publication/PubMed/29125738", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "rs3412743494", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3412743494", "database": "dbSNP", "categories": [ "Other" ] }, { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ARQRQLMHERLFGHSSTSAL", "down_seq": "AILRSPAFTSRLSGNRGVQY", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser3122", "evidence": [ { "id": "36288343", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36288343" }, { "id": "Q7TMY8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8" }, { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "39627609", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39627609" }, { "id": "29125738", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29125738" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" } ] } ], "snv": [ { "evidence": [ { "id": "rs3412743494", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3412743494" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "S", "sequence_mut": "P", "comment": "Germline mutation passed 1 filters: o-glyco-site-loss (S->P).", "chr_id": "X", "chr_pos": "150700382", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S3122", "keywords": [ "ebi", "germline" ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "site_lbl": "Ser3122" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "glycosylation_flag", "snv_flag", "phosphorylation_flag" ], "mutagenesis": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "Q7TMY8-1.3116.3116", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q7TMY8-1.3117.3117", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q7TMY8-1.3118.3118", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q7TMY8-1.3127.3127", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q7TMY8-1.3135.3135", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 7 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q7TMY8-1.3400.3400", "start_pos": 3400, "end_pos": 3400, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "SSSSGICTDFWDLLVKLDNM", "down_seq": "VSRKGKNSVKSVPVSSGGEG", "glycosylation": [ { "glytoucan_ac": "G29299MO", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "LDNMNVSR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn3400", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q7TMY8-1.3504.3504", "start_pos": 3504, "end_pos": 3504, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "TAATSNTSTTTTTTTTATAP", "down_seq": "PTPPAATTPVTSAPALVAAT", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3504", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "Q7TMY8-1.3506.3506", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q7TMY8-1.3506.3506", "start_pos": 3506, "end_pos": 3506, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "ATSNTSTTTTTTTTATAPTP", "down_seq": "PPAATTPVTSAPALVAATAI", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3506", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "Q7TMY8-1.3504.3504", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q7TMY8-1.3799.3799", "start_pos": 3799, "end_pos": 3799, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "MVREGQRARRQQQAATSESS", "down_seq": "QSETSVRREESPMDVDQPSP", "glycosylation": [ { "glytoucan_ac": "G62765YT", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "QQQAATSESSNQSETSVR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn3799", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "upstream", "id": "Q7TMY8-1.3810.3810", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q7TMY8-1.3818.3818", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q7TMY8-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Differential Detection of O-GlcNAcylated proteins in the heart using antibodies.", "journal": "Analytical biochemistry", "date": "2023-10-01", "authors": "Narayanan Bhargavi, Zahra Fiddia, Reeves Russell A, Aggarwal Akanksha, O'Meally Robert N, Henry Roger K, Craven Megan, Jacobson Avital, Cole Robert N, Kohr Mark J, Umapathi Priya, Zachara Natasha E", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q7TMY8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081" } ] } ], "crossref": [ { "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q7TMY8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "37507081", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37507081" }, { "id": "Q7TMY8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7TMY8" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q7TMY8-1.2093.2093", "start_pos": 2093, "end_pos": 2093, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3389536411", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389536411", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RLLAELVRSYVGIATLIANY", "down_seq": "YTVGQSELIKEDCSVLAFVL", "snv": [ { "evidence": [ { "id": "rs3389536411", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389536411" } ], "glycoeffect": [ "n-glyco-sequon-gain", "n-glyco-sequon-loss", "o-glyco-site-loss" ], "sequence_org": "S", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (SYT->NYT).", "chr_id": "X", "chr_pos": "150681623", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S2093", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q7TMY8-1.2246.2246", "start_pos": 2246, "end_pos": 2246, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3412158455", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3412158455", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "A", "start_aa": "A", "up_seq": "ARVPHSLDLSSPNMANTVNA", "down_seq": "LKPLETLSRIVNQPSSLFGS", "snv": [ { "evidence": [ { "id": "rs3412158455", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3412158455" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "A", "sequence_mut": "S", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (NAA->NAS).", "chr_id": "X", "chr_pos": "150686850", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "A2246", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "upstream", "id": "Q7TMY8-1.2266.2266", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q7TMY8-1.2558.2558", "start_pos": 2558, "end_pos": 2558, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3389558387", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389558387", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "G", "start_aa": "G", "up_seq": "RLTQGIGRSQRTLRQLTANT", "down_seq": "HTIHVHYPGNRQPNPPLILQ", "snv": [ { "evidence": [ { "id": "rs3389558387", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389558387" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "G", "sequence_mut": "C", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (NTG->NTC).", "chr_id": "X", "chr_pos": "150691888", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "G2558", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "Q7TMY8-1.2554.2554", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q7TMY8-1.1084.1084", "start_pos": 1084, "end_pos": 1084, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AELFGLLVKLCVGSPVRQRR", "down_seq": "HHAASTTTAPTPAARSTASA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "site_lbl": "Ser1084" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "upstream", "id": "Q7TMY8-1.1095.1095", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q7TMY8-1.1368.1368", "start_pos": 1368, "end_pos": 1368, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" }, { "database": "iPTMnet", "id": "Q7TMY8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q7TMY8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q7TMY8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ATEYLLTHPPPIIGGVVRDL", "down_seq": "MSEEDQMMRAIAMSLGQDIP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q7TMY8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q7TMY8" } ], "site_lbl": "Ser1368" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "Q7TMY8-1.1370.1370", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q7TMY8-1.1382.1382", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q7TMY8-1.1370.1370", "start_pos": 1370, "end_pos": 1370, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EYLLTHPPPIIGGVVRDLSM", "down_seq": "EEDQMMRAIAMSLGQDIPMD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "site_lbl": "Ser1370" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "Q7TMY8-1.1368.1368", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "Q7TMY8-1.1382.1382", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q7TMY8-1.1382.1382", "start_pos": 1382, "end_pos": 1382, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GVVRDLSMSEEDQMMRAIAM", "down_seq": "LGQDIPMDQRAESPEEVACR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "site_lbl": "Ser1382" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "Q7TMY8-1.1368.1368", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "Q7TMY8-1.1370.1370", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q7TMY8-1.1395.1395", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q7TMY8-1.1395.1395", "start_pos": 1395, "end_pos": 1395, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" }, { "database": "iPTMnet", "id": "Q7TMY8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" }, { "database": "iPTMnet", "id": "Q7TMY8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] } ], "crossref": [ { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q7TMY8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q7TMY8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MMRAIAMSLGQDIPMDQRAE", "down_seq": "PEEVACRKEEEERKAREKQE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" }, { "database": "iPTMnet", "id": "Q7TMY8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q7TMY8" } ], "site_lbl": "Ser1395" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "Q7TMY8-1.1382.1382", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q7TMY8-1.1907.1907", "start_pos": 1907, "end_pos": 1907, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" }, { "database": "iPTMnet", "id": "Q7TMY8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] }, { "title": "Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.", "journal": "Molecular & cellular proteomics : MCP", "date": "2009", "authors": "Sweet SM, Bailey CM, Cunningham DL, Heath JK, Cooper HJ", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" }, { "database": "iPTMnet", "id": "Q7TMY8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "19131326", "url": "https://glygen.org/publication/PubMed/19131326" } ] }, { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" }, { "database": "iPTMnet", "id": "Q7TMY8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19131326", "url": "https://glygen.org/publication/PubMed/19131326", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q7TMY8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q7TMY8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EVANCCIRIALPAPRGSGTA", "down_seq": "DDEFENLRIKGPNAVQLVKT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" }, { "database": "PubMed", "id": "19131326", "url": "https://glygen.org/publication/PubMed/19131326" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q7TMY8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q7TMY8" } ], "site_lbl": "Ser1907" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q7TMY8-1.2035.2035", "start_pos": 2035, "end_pos": 2035, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "AADGAPAETSTTGTSQGEAS", "down_seq": "PEETREGKKDKEGDRTSEEG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "site_lbl": "Thr2035" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q7TMY8-1.2266.2266", "start_pos": 2266, "end_pos": 2266, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ALKPLETLSRIVNQPSSLFG", "down_seq": "KSASSKNKSEQDAQGASQDS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "site_lbl": "Ser2266" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "Q7TMY8-1.2246.2246", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q7TMY8-1.2362.2362", "start_pos": 2362, "end_pos": 2362, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" }, { "database": "iPTMnet", "id": "Q7TMY8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q7TMY8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q7TMY8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MQVENELEDLIDELLERDGG", "down_seq": "GNSTIIVSRSGEDESQEDVL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q7TMY8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q7TMY8" } ], "site_lbl": "Ser2362" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "Q7TMY8-1.2365.2365", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q7TMY8-1.2365.2365", "start_pos": 2365, "end_pos": 2365, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ENELEDLIDELLERDGGSGN", "down_seq": "TIIVSRSGEDESQEDVLMDE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "site_lbl": "Ser2365" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "Q7TMY8-1.2362.2362", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q7TMY8-1.2391.2391", "start_pos": 2391, "end_pos": 2391, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RSGEDESQEDVLMDEAPSNL", "down_seq": "QASTLQANREDSMNILDPED", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "site_lbl": "Ser2391" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q7TMY8-1.2527.2527", "start_pos": 2527, "end_pos": 2527, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PSPGNIPTTHPLMVRHADHS", "down_seq": "LTLGSGSSTTRLTQGIGRSQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "site_lbl": "Ser2527" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "upstream", "id": "Q7TMY8-1.2532.2532", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q7TMY8-1.2535.2535", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q7TMY8-1.2532.2532", "start_pos": 2532, "end_pos": 2532, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "IPTTHPLMVRHADHSSLTLG", "down_seq": "GSSTTRLTQGIGRSQRTLRQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "site_lbl": "Ser2532" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "Q7TMY8-1.2527.2527", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q7TMY8-1.2535.2535", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q7TMY8-1.2535.2535", "start_pos": 2535, "end_pos": 2535, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "THPLMVRHADHSSLTLGSGS", "down_seq": "TTRLTQGIGRSQRTLRQLTA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "site_lbl": "Ser2535" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "Q7TMY8-1.2527.2527", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q7TMY8-1.2532.2532", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q7TMY8-1.2554.2554", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q7TMY8-1.2554.2554", "start_pos": 2554, "end_pos": 2554, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "SSTTRLTQGIGRSQRTLRQL", "down_seq": "ANTGHTIHVHYPGNRQPNPP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "site_lbl": "Thr2554" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "Q7TMY8-1.2535.2535", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q7TMY8-1.2558.2558", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q7TMY8-1.2584.2584", "start_pos": 2584, "end_pos": 2584, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "HYPGNRQPNPPLILQRLLGP", "down_seq": "AAADILQLSSSLPLQSRGRA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "site_lbl": "Ser2584" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "upstream", "id": "Q7TMY8-1.2595.2595", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q7TMY8-1.2595.2595", "start_pos": 2595, "end_pos": 2595, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LILQRLLGPSAAADILQLSS", "down_seq": "LPLQSRGRARLLVGNDDVHI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "site_lbl": "Ser2595" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "Q7TMY8-1.2584.2584", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q7TMY8-1.2751.2751", "start_pos": 2751, "end_pos": 2751, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "EQNVSDGTPMPDSYPTTPSS", "down_seq": "DAPTSESKETLGTLQPSQQQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "site_lbl": "Thr2751" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "Q7TMY8-1.2747.2747", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q7TMY8-1.2826.2826", "start_pos": 2826, "end_pos": 2826, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LEELGPTRPSGEAETTQMEL", "down_seq": "PAPTITSLSPERAEDSDALT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "site_lbl": "Ser2826" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "upstream", "id": "Q7TMY8-1.2833.2833", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q7TMY8-1.2835.2835", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q7TMY8-1.2833.2833", "start_pos": 2833, "end_pos": 2833, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RPSGEAETTQMELSPAPTIT", "down_seq": "LSPERAEDSDALTAVSSQLE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "site_lbl": "Ser2833" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "Q7TMY8-1.2826.2826", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q7TMY8-1.2835.2835", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q7TMY8-1.2835.2835", "start_pos": 2835, "end_pos": 2835, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SGEAETTQMELSPAPTITSL", "down_seq": "PERAEDSDALTAVSSQLEGS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "site_lbl": "Ser2835" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "Q7TMY8-1.2826.2826", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q7TMY8-1.2833.2833", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q7TMY8-1.2861.2861", "start_pos": 2861, "end_pos": 2861, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DSDALTAVSSQLEGSPMDTS", "down_seq": "LASCTLEEAVGDTPAAGSSE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "site_lbl": "Ser2861" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "upstream", "id": "Q7TMY8-1.2874.2874", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q7TMY8-1.2887.2887", "start_pos": 2887, "end_pos": 2887, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LEEAVGDTPAAGSSEQPTAG", "down_seq": "STPGDAPSVVAEVQGRPDVS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "site_lbl": "Ser2887" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "Q7TMY8-1.2874.2874", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q7TMY8-1.2888.2888", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q7TMY8-1.2889.2889", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q7TMY8-1.2888.2888", "start_pos": 2888, "end_pos": 2888, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EEAVGDTPAAGSSEQPTAGS", "down_seq": "TPGDAPSVVAEVQGRPDVSR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "site_lbl": "Ser2888" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "Q7TMY8-1.2874.2874", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q7TMY8-1.2887.2887", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q7TMY8-1.2889.2889", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q7TMY8-1.2918.2918", "start_pos": 2918, "end_pos": 2918, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AEVQGRPDVSRESNQPPEDS", "down_seq": "PPASSESSSTRDSAVAISGA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "site_lbl": "Ser2918" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q7TMY8-1.3127.3127", "start_pos": 3127, "end_pos": 3127, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LMHERLFGHSSTSALSAILR", "down_seq": "PAFTSRLSGNRGVQYTRLAV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "site_lbl": "Ser3127" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "Q7TMY8-1.3116.3116", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "Q7TMY8-1.3117.3117", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "Q7TMY8-1.3118.3118", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q7TMY8-1.3122.3122", "categories": [ "glycosylation_flag", "snv_flag", "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q7TMY8-1.3135.3135", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q7TMY8-1.3135.3135", "start_pos": 3135, "end_pos": 3135, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "HSSTSALSAILRSPAFTSRL", "down_seq": "GNRGVQYTRLAVQRGGTFQM", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "site_lbl": "Ser3135" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "Q7TMY8-1.3116.3116", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 18, "direction": "downstream", "id": "Q7TMY8-1.3117.3117", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 17, "direction": "downstream", "id": "Q7TMY8-1.3118.3118", "categories": [ "glycosylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "Q7TMY8-1.3122.3122", "categories": [ "glycosylation_flag", "snv_flag", "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "Q7TMY8-1.3127.3127", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q7TMY8-1.3557.3557", "start_pos": 3557, "end_pos": 3557, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VTTPTTATTTVSTSTTKGSK", "down_seq": "PAKVGEGGSGIDFKMVSSGL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "site_lbl": "Ser3557" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q7TMY8-1.3663.3663", "start_pos": 3663, "end_pos": 3663, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LAELREYNLEQQRRAQCETL", "down_seq": "PDGLPEEQPQTTKLKGKMQS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "site_lbl": "Ser3663" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q7TMY8-1.3753.3753", "start_pos": 3753, "end_pos": 3753, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QLRDDTRRANKKAKQTGRLG", "down_seq": "SGLGSASSIQAAVRQLEAEA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "site_lbl": "Ser3753" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "upstream", "id": "Q7TMY8-1.3758.3758", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q7TMY8-1.3760.3760", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q7TMY8-1.3761.3761", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q7TMY8-1.3758.3758", "start_pos": 3758, "end_pos": 3758, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" }, { "database": "iPTMnet", "id": "Q7TMY8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q7TMY8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q7TMY8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TRRANKKAKQTGRLGSSGLG", "down_seq": "ASSIQAAVRQLEAEADAIIQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q7TMY8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q7TMY8" } ], "site_lbl": "Ser3758" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "Q7TMY8-1.3753.3753", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q7TMY8-1.3760.3760", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q7TMY8-1.3761.3761", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q7TMY8-1.3760.3760", "start_pos": 3760, "end_pos": 3760, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RANKKAKQTGRLGSSGLGSA", "down_seq": "SIQAAVRQLEAEADAIIQMV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "site_lbl": "Ser3760" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "Q7TMY8-1.3753.3753", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q7TMY8-1.3758.3758", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q7TMY8-1.3761.3761", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q7TMY8-1.3761.3761", "start_pos": 3761, "end_pos": 3761, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" }, { "database": "iPTMnet", "id": "Q7TMY8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q7TMY8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q7TMY8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ANKKAKQTGRLGSSGLGSAS", "down_seq": "IQAAVRQLEAEADAIIQMVR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q7TMY8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q7TMY8" } ], "site_lbl": "Ser3761" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "Q7TMY8-1.3753.3753", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q7TMY8-1.3758.3758", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q7TMY8-1.3760.3760", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q7TMY8-1.3810.3810", "start_pos": 3810, "end_pos": 3810, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" }, { "database": "iPTMnet", "id": "Q7TMY8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] }, { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" }, { "database": "iPTMnet", "id": "Q7TMY8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q7TMY8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q7TMY8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QQAATSESSNQSETSVRREE", "down_seq": "PMDVDQPSPSAQDTQSIVIS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q7TMY8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q7TMY8" } ], "site_lbl": "Ser3810" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "Q7TMY8-1.3799.3799", "categories": [ "glycosylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q7TMY8-1.3818.3818", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "Q7TMY8-1.3830.3830", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q7TMY8-1.3818.3818", "start_pos": 3818, "end_pos": 3818, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" }, { "database": "iPTMnet", "id": "Q7TMY8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q7TMY8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q7TMY8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SNQSETSVRREESPMDVDQP", "down_seq": "PSAQDTQSIVISDGTPQGEK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q7TMY8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q7TMY8" } ], "site_lbl": "Ser3818" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "Q7TMY8-1.3799.3799", "categories": [ "glycosylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "Q7TMY8-1.3810.3810", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "Q7TMY8-1.3830.3830", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q7TMY8-1.3833.3833", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q7TMY8-1.3830.3830", "start_pos": 3830, "end_pos": 3830, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SPMDVDQPSPSAQDTQSIVI", "down_seq": "DGTPQGEKEKEEKPPELPLL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "site_lbl": "Ser3830" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "Q7TMY8-1.3810.3810", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "Q7TMY8-1.3818.3818", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q7TMY8-1.3833.3833", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q7TMY8-1.3833.3833", "start_pos": 3833, "end_pos": 3833, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "DVDQPSPSAQDTQSIVISDG", "down_seq": "PQGEKEKEEKPPELPLLSEQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "site_lbl": "Thr3833" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "Q7TMY8-1.3818.3818", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q7TMY8-1.3830.3830", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q7TMY8-1.3909.3909", "start_pos": 3909, "end_pos": 3909, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "FFLVHATERESKPPVRDTRE", "down_seq": "QLAHIKDEPPPLSPAPLTPA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "site_lbl": "Ser3909" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "upstream", "id": "Q7TMY8-1.3922.3922", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q7TMY8-1.3927.3927", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q7TMY8-1.3922.3922", "start_pos": 3922, "end_pos": 3922, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" }, { "database": "iPTMnet", "id": "Q7TMY8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q7TMY8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q7TMY8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PVRDTRESQLAHIKDEPPPL", "down_seq": "PAPLTPATPSSLDPFFSREP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q7TMY8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q7TMY8" } ], "site_lbl": "Ser3922" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "Q7TMY8-1.3909.3909", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q7TMY8-1.3927.3927", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q7TMY8-1.3930.3930", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q7TMY8-1.3927.3927", "start_pos": 3927, "end_pos": 3927, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" }, { "database": "iPTMnet", "id": "Q7TMY8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q7TMY8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q7TMY8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "RESQLAHIKDEPPPLSPAPL", "down_seq": "PATPSSLDPFFSREPSSMHI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q7TMY8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q7TMY8" } ], "site_lbl": "Thr3927" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "Q7TMY8-1.3909.3909", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q7TMY8-1.3922.3922", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q7TMY8-1.3930.3930", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q7TMY8-1.3930.3930", "start_pos": 3930, "end_pos": 3930, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" }, { "database": "iPTMnet", "id": "Q7TMY8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q7TMY8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q7TMY8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "QLAHIKDEPPPLSPAPLTPA", "down_seq": "PSSLDPFFSREPSSMHISSS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q7TMY8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q7TMY8" } ], "site_lbl": "Thr3930" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "Q7TMY8-1.3922.3922", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q7TMY8-1.3927.3927", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q7TMY8-1.4274.4274", "start_pos": 4274, "end_pos": 4274, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "ISGLPTIDIDDLKSNTEYHK", "down_seq": "QSNSIQIQWFWRALRSFDQA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "site_lbl": "Tyr4274" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q7TMY8-1.648.648", "start_pos": 648, "end_pos": 648, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" }, { "database": "iPTMnet", "id": "Q7TMY8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q7TMY8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q7TMY8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ERLFKVLLSPDYLPAMRRRR", "down_seq": "SDPLGDTASNLGSAVDELMR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q7TMY8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q7TMY8" } ], "site_lbl": "Ser648" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "Q7TMY8-1.649.649", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q7TMY8-1.649.649", "start_pos": 649, "end_pos": 649, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" }, { "database": "iPTMnet", "id": "Q7TMY8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q7TMY8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q7TMY8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q7TMY8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RLFKVLLSPDYLPAMRRRRS", "down_seq": "DPLGDTASNLGSAVDELMRH", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q7TMY8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q7TMY8" } ], "site_lbl": "Ser649" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "Q7TMY8-1.648.648", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q7TMY8-1.740.740", "start_pos": 740, "end_pos": 740, "uniprot_canonical_ac": "Q7TMY8-1", "length": 4377, "uniprot_id": "HUWE1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HUWE1", "refseq_ac": "NP_067498", "refseq_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "gene_names_uniprotkb": "Huwe1; Kiaa0312; Ureb1", "gene_names_refseq": "5430439H10Rik; Arf-bp1; C430014N20Rik; Gm1718; Huwe1; Ib772; LASU1; Mule; Ureb1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "HAAEEASSEDEEEEEVQAMQ", "down_seq": "FNSAQQNETEPNQQVVGTEE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q7TMY8", "url": "https://www.uniprot.org/uniprotkb/Q7TMY8" } ], "site_lbl": "Ser740" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1095", "end_pos": "1095" }, { "start_pos": "2169", "end_pos": "2169" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2632", "end_pos": "2632" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2747", "end_pos": "2747" }, { "start_pos": "2874", "end_pos": "2874" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3118", "end_pos": "3118" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3400", "end_pos": "3400" }, { "start_pos": "3504", "end_pos": "3504" }, { "start_pos": "3506", "end_pos": "3506" }, { "start_pos": "3799", "end_pos": "3799" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2093", "end_pos": "2093" }, { "start_pos": "2246", "end_pos": "2246" }, { "start_pos": "2558", "end_pos": "2558" }, { "start_pos": "3122", "end_pos": "3122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1084", "end_pos": "1084" }, { "start_pos": "1368", "end_pos": "1368" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1382", "end_pos": "1382" }, { "start_pos": "1395", "end_pos": "1395" }, { "start_pos": "1907", "end_pos": "1907" }, { "start_pos": "2035", "end_pos": "2035" }, { "start_pos": "2266", "end_pos": "2266" }, { "start_pos": "2362", "end_pos": "2362" }, { "start_pos": "2365", "end_pos": "2365" }, { "start_pos": "2391", "end_pos": "2391" }, { "start_pos": "2527", "end_pos": "2527" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2584", "end_pos": "2584" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2619", "end_pos": "2619" }, { "start_pos": "2751", "end_pos": "2751" }, { "start_pos": "2826", "end_pos": "2826" }, { "start_pos": "2833", "end_pos": "2833" }, { "start_pos": "2835", "end_pos": "2835" }, { "start_pos": "2861", "end_pos": "2861" }, { "start_pos": "2887", "end_pos": "2887" }, { "start_pos": "2888", "end_pos": "2888" }, { "start_pos": "2889", "end_pos": "2889" }, { "start_pos": "2918", "end_pos": "2918" }, { "start_pos": "3116", "end_pos": "3116" }, { "start_pos": "3117", "end_pos": "3117" }, { "start_pos": "3122", "end_pos": "3122" }, { "start_pos": "3127", "end_pos": "3127" }, { "start_pos": "3135", "end_pos": "3135" }, { "start_pos": "3557", "end_pos": "3557" }, { "start_pos": "3663", "end_pos": "3663" }, { "start_pos": "3753", "end_pos": "3753" }, { "start_pos": "3758", "end_pos": "3758" }, { "start_pos": "3760", "end_pos": "3760" }, { "start_pos": "3761", "end_pos": "3761" }, { "start_pos": "3810", "end_pos": "3810" }, { "start_pos": "3818", "end_pos": "3818" }, { "start_pos": "3830", "end_pos": "3830" }, { "start_pos": "3833", "end_pos": "3833" }, { "start_pos": "3909", "end_pos": "3909" }, { "start_pos": "3922", "end_pos": "3922" }, { "start_pos": "3927", "end_pos": "3927" }, { "start_pos": "3930", "end_pos": "3930" }, { "start_pos": "4274", "end_pos": "4274" }, { "start_pos": "648", "end_pos": "648" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "740", "end_pos": "740" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9D236-3.311.311", "start_pos": 311, "end_pos": 311, "uniprot_canonical_ac": "Q9D236-3", "length": 459, "uniprot_id": "HTRA3_MOUSE", "protein_name": "Serine protease HTRA3", "refseq_ac": "NP_001036080", "refseq_name": "serine protease HTRA3 isoform b precursor", "gene_name": "Htra3", "gene_names_uniprotkb": "Htra3; Prsp; Tasp", "gene_names_refseq": "2210021K23Rik; 9530081K03Rik; Htra3; Prsp; Tasp", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D236", "url": "https://www.uniprot.org/uniprotkb/Q9D236" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Developmentally regulated expression of mouse HtrA3 and its role as an inhibitor of TGF-beta signaling.", "journal": "Development, growth & differentiation", "date": "2004", "authors": "Tocharus J, Tsuchiya A, Kajikawa M, Ueta Y, Oka C, Kawaichi M", "evidence": [ { "database": "UniProtKB", "id": "Q9D236", "url": "https://www.uniprot.org/uniprotkb/Q9D236" } ], "reference": [ { "type": "PubMed", "id": "15206957", "url": "https://glygen.org/publication/PubMed/15206957" } ] } ], "crossref": [ { "id": "Q9D236", "url": "https://www.uniprot.org/uniprotkb/Q9D236", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "15206957", "url": "https://glygen.org/publication/PubMed/15206957", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GLRDSDMDYIQTDAIINYGN", "down_seq": "GGPLVNLDGEVIGINTLKVA", "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Abolishes protease activity. No inhibition of BMP4-mediated signaling.", "evidence": [ { "database": "UniProtKB", "id": "Q9D236", "url": "https://www.uniprot.org/uniprotkb/Q9D236" }, { "database": "PubMed", "id": "15206957", "url": "https://glygen.org/publication/PubMed/15206957" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "311", "end_pos": "311" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6P4S8-1.1655.1655", "start_pos": 1655, "end_pos": 1655, "uniprot_canonical_ac": "Q6P4S8-1", "length": 2195, "uniprot_id": "INT1_MOUSE", "protein_name": "Integrator complex subunit 1", "refseq_ac": "NP_081024", "refseq_name": "integrator complex subunit 1", "gene_name": "Ints1", "gene_names_uniprotkb": "Ints1", "gene_names_refseq": "1110015K06Rik; Ints1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6P4S8", "url": "https://www.uniprot.org/uniprotkb/Q6P4S8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Quantitative Profiling of Protein O-GlcNAcylation Sites by an Isotope-Tagged Cleavable Linker.", "journal": "ACS chemical biology", "date": "2018", "authors": "Qin K, Zhu Y, Qin W, Gao J, Shao X, Wang YL, Zhou W, Wang C, Chen X", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q6P4S8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q6P4S8" }, { "database": "O-GlcNAc Atlas", "id": "Q6P4S8", "url": "https://oglcnac.org/atlas/detail/Q6P4S8" } ], "reference": [ { "type": "PubMed", "id": "30059200", "url": "https://glygen.org/publication/PubMed/30059200" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q6P4S8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q6P4S8" }, { "database": "O-GlcNAc Atlas", "id": "Q6P4S8", "url": "https://oglcnac.org/atlas/detail/Q6P4S8" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] } ], "crossref": [ { "id": "30059200", "url": "https://glygen.org/publication/PubMed/30059200", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q6P4S8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q6P4S8", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q6P4S8", "url": "https://oglcnac.org/atlas/detail/Q6P4S8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SCPDLQWKLLFSRRKGKGHI", "down_seq": "AQVLSFRPYLLALLTHQASW", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1655", "evidence": [ { "id": "30059200", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30059200" }, { "id": "Q6P4S8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q6P4S8" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "Q6P4S8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q6P4S8" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1655", "end_pos": "1655" }, { "start_pos": "1660", "end_pos": "1660" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "859", "end_pos": "859" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "1328", "end_pos": "1328" }, { "start_pos": "1329", "end_pos": "1329" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "926", "end_pos": "926" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "upstream", "id": "Q6P4S8-1.1660.1660", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6P4S8-1.1660.1660", "start_pos": 1660, "end_pos": 1660, "uniprot_canonical_ac": "Q6P4S8-1", "length": 2195, "uniprot_id": "INT1_MOUSE", "protein_name": "Integrator complex subunit 1", "refseq_ac": "NP_081024", "refseq_name": "integrator complex subunit 1", "gene_name": "Ints1", "gene_names_uniprotkb": "Ints1", "gene_names_refseq": "1110015K06Rik; Ints1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6P4S8", "url": "https://www.uniprot.org/uniprotkb/Q6P4S8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Quantitative Profiling of Protein O-GlcNAcylation Sites by an Isotope-Tagged Cleavable Linker.", "journal": "ACS chemical biology", "date": "2018", "authors": "Qin K, Zhu Y, Qin W, Gao J, Shao X, Wang YL, Zhou W, Wang C, Chen X", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q6P4S8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q6P4S8" }, { "database": "O-GlcNAc Atlas", "id": "Q6P4S8", "url": "https://oglcnac.org/atlas/detail/Q6P4S8" } ], "reference": [ { "type": "PubMed", "id": "30059200", "url": "https://glygen.org/publication/PubMed/30059200" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q6P4S8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q6P4S8" }, { "database": "O-GlcNAc Atlas", "id": "Q6P4S8", "url": "https://oglcnac.org/atlas/detail/Q6P4S8" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] } ], "crossref": [ { "id": "30059200", "url": "https://glygen.org/publication/PubMed/30059200", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q6P4S8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q6P4S8", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q6P4S8", "url": "https://oglcnac.org/atlas/detail/Q6P4S8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QWKLLFSRRKGKGHISAQVL", "down_seq": "FRPYLLALLTHQASWSTLHC", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1660", "evidence": [ { "id": "30059200", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30059200" }, { "id": "Q6P4S8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q6P4S8" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "Q6P4S8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q6P4S8" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1655", "end_pos": "1655" }, { "start_pos": "1660", "end_pos": "1660" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "859", "end_pos": "859" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "1328", "end_pos": "1328" }, { "start_pos": "1329", "end_pos": "1329" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "926", "end_pos": "926" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "Q6P4S8-1.1655.1655", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6P4S8-1.347.347", "start_pos": 347, "end_pos": 347, "uniprot_canonical_ac": "Q6P4S8-1", "length": 2195, "uniprot_id": "INT1_MOUSE", "protein_name": "Integrator complex subunit 1", "refseq_ac": "NP_081024", "refseq_name": "integrator complex subunit 1", "gene_name": "Ints1", "gene_names_uniprotkb": "Ints1", "gene_names_refseq": "1110015K06Rik; Ints1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6P4S8", "url": "https://www.uniprot.org/uniprotkb/Q6P4S8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "VEEYVLDMLRDQLNRRQPID", "down_seq": "VSRNLLRLLTATCGYKEVRL", "glycosylation": [ { "glytoucan_ac": "G63041LO", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "DQLNRRQPIDNVSR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn347", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1655", "end_pos": "1655" }, { "start_pos": "1660", "end_pos": "1660" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "859", "end_pos": "859" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "1328", "end_pos": "1328" }, { "start_pos": "1329", "end_pos": "1329" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "926", "end_pos": "926" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6P4S8-1.859.859", "start_pos": 859, "end_pos": 859, "uniprot_canonical_ac": "Q6P4S8-1", "length": 2195, "uniprot_id": "INT1_MOUSE", "protein_name": "Integrator complex subunit 1", "refseq_ac": "NP_081024", "refseq_name": "integrator complex subunit 1", "gene_name": "Ints1", "gene_names_uniprotkb": "Ints1", "gene_names_refseq": "1110015K06Rik; Ints1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6P4S8", "url": "https://www.uniprot.org/uniprotkb/Q6P4S8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "DPQGPPRRPPPHILDQVKAL", "down_seq": "QSLRLGHLLCRSRNPDFLLH", "glycosylation": [ { "glytoucan_ac": "G02815KT", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "ALNQSLR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn859", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1655", "end_pos": "1655" }, { "start_pos": "1660", "end_pos": "1660" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "859", "end_pos": "859" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "1328", "end_pos": "1328" }, { "start_pos": "1329", "end_pos": "1329" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "926", "end_pos": "926" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6P4S8-1.1320.1320", "start_pos": 1320, "end_pos": 1320, "uniprot_canonical_ac": "Q6P4S8-1", "length": 2195, "uniprot_id": "INT1_MOUSE", "protein_name": "Integrator complex subunit 1", "refseq_ac": "NP_081024", "refseq_name": "integrator complex subunit 1", "gene_name": "Ints1", "gene_names_uniprotkb": "Ints1", "gene_names_refseq": "1110015K06Rik; Ints1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6P4S8", "url": "https://www.uniprot.org/uniprotkb/Q6P4S8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q6P4S8", "url": "https://www.uniprot.org/uniprotkb/Q6P4S8" }, { "database": "iPTMnet", "id": "Q6P4S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6P4S8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q6P4S8", "url": "https://www.uniprot.org/uniprotkb/Q6P4S8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q6P4S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6P4S8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ASGGQTFHSLLTASLPPRRD", "down_seq": "TEAPKPESSPEPPPGQGRTR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q6P4S8", "url": "https://www.uniprot.org/uniprotkb/Q6P4S8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q6P4S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6P4S8" } ], "site_lbl": "Ser1320" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1655", "end_pos": "1655" }, { "start_pos": "1660", "end_pos": "1660" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "859", "end_pos": "859" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "1328", "end_pos": "1328" }, { "start_pos": "1329", "end_pos": "1329" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "926", "end_pos": "926" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "upstream", "id": "Q6P4S8-1.1328.1328", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q6P4S8-1.1329.1329", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6P4S8-1.1328.1328", "start_pos": 1328, "end_pos": 1328, "uniprot_canonical_ac": "Q6P4S8-1", "length": 2195, "uniprot_id": "INT1_MOUSE", "protein_name": "Integrator complex subunit 1", "refseq_ac": "NP_081024", "refseq_name": "integrator complex subunit 1", "gene_name": "Ints1", "gene_names_uniprotkb": "Ints1", "gene_names_refseq": "1110015K06Rik; Ints1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6P4S8", "url": "https://www.uniprot.org/uniprotkb/Q6P4S8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q6P4S8", "url": "https://www.uniprot.org/uniprotkb/Q6P4S8" }, { "database": "iPTMnet", "id": "Q6P4S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6P4S8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q6P4S8", "url": "https://www.uniprot.org/uniprotkb/Q6P4S8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q6P4S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6P4S8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SLLTASLPPRRDSTEAPKPE", "down_seq": "SPEPPPGQGRTRAGTQVPVL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q6P4S8", "url": "https://www.uniprot.org/uniprotkb/Q6P4S8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q6P4S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6P4S8" } ], "site_lbl": "Ser1328" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1655", "end_pos": "1655" }, { "start_pos": "1660", "end_pos": "1660" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "859", "end_pos": "859" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "1328", "end_pos": "1328" }, { "start_pos": "1329", "end_pos": "1329" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "926", "end_pos": "926" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "Q6P4S8-1.1320.1320", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q6P4S8-1.1329.1329", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6P4S8-1.1329.1329", "start_pos": 1329, "end_pos": 1329, "uniprot_canonical_ac": "Q6P4S8-1", "length": 2195, "uniprot_id": "INT1_MOUSE", "protein_name": "Integrator complex subunit 1", "refseq_ac": "NP_081024", "refseq_name": "integrator complex subunit 1", "gene_name": "Ints1", "gene_names_uniprotkb": "Ints1", "gene_names_refseq": "1110015K06Rik; Ints1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6P4S8", "url": "https://www.uniprot.org/uniprotkb/Q6P4S8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q6P4S8", "url": "https://www.uniprot.org/uniprotkb/Q6P4S8" }, { "database": "iPTMnet", "id": "Q6P4S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6P4S8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q6P4S8", "url": "https://www.uniprot.org/uniprotkb/Q6P4S8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q6P4S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6P4S8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LLTASLPPRRDSTEAPKPES", "down_seq": "PEPPPGQGRTRAGTQVPVLG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q6P4S8", "url": "https://www.uniprot.org/uniprotkb/Q6P4S8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q6P4S8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6P4S8" } ], "site_lbl": "Ser1329" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1655", "end_pos": "1655" }, { "start_pos": "1660", "end_pos": "1660" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "859", "end_pos": "859" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "1328", "end_pos": "1328" }, { "start_pos": "1329", "end_pos": "1329" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "926", "end_pos": "926" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "Q6P4S8-1.1320.1320", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q6P4S8-1.1328.1328", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6P4S8-1.13.13", "start_pos": 13, "end_pos": 13, "uniprot_canonical_ac": "Q6P4S8-1", "length": 2195, "uniprot_id": "INT1_MOUSE", "protein_name": "Integrator complex subunit 1", "refseq_ac": "NP_081024", "refseq_name": "integrator complex subunit 1", "gene_name": "Ints1", "gene_names_uniprotkb": "Ints1", "gene_names_refseq": "1110015K06Rik; Ints1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6P4S8", "url": "https://www.uniprot.org/uniprotkb/Q6P4S8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q6P4S8", "url": "https://www.uniprot.org/uniprotkb/Q6P4S8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MNRAKPTTVRRP", "down_seq": "AAAKPSGHPPPGDFIALGSK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q6P4S8", "url": "https://www.uniprot.org/uniprotkb/Q6P4S8" } ], "site_lbl": "Ser13" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1655", "end_pos": "1655" }, { "start_pos": "1660", "end_pos": "1660" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "859", "end_pos": "859" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "1328", "end_pos": "1328" }, { "start_pos": "1329", "end_pos": "1329" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "926", "end_pos": "926" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q6P4S8-1.307.307", "start_pos": 307, "end_pos": 307, "uniprot_canonical_ac": "Q6P4S8-1", "length": 2195, "uniprot_id": "INT1_MOUSE", "protein_name": "Integrator complex subunit 1", "refseq_ac": "NP_081024", "refseq_name": "integrator complex subunit 1", "gene_name": "Ints1", "gene_names_uniprotkb": "Ints1", "gene_names_refseq": "1110015K06Rik; Ints1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6P4S8", "url": "https://www.uniprot.org/uniprotkb/Q6P4S8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q6P4S8", "url": "https://www.uniprot.org/uniprotkb/Q6P4S8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PSLTEEEDSQTELLIAEEKL", "down_seq": "PEQEGQLMPRPRYDELTESV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q6P4S8", "url": "https://www.uniprot.org/uniprotkb/Q6P4S8" } ], "site_lbl": "Ser307" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1655", "end_pos": "1655" }, { "start_pos": "1660", "end_pos": "1660" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "859", "end_pos": "859" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "1328", "end_pos": "1328" }, { "start_pos": "1329", "end_pos": "1329" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "926", "end_pos": "926" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q6P4S8-1.83.83", "start_pos": 83, "end_pos": 83, "uniprot_canonical_ac": "Q6P4S8-1", "length": 2195, "uniprot_id": "INT1_MOUSE", "protein_name": "Integrator complex subunit 1", "refseq_ac": "NP_081024", "refseq_name": "integrator complex subunit 1", "gene_name": "Ints1", "gene_names_uniprotkb": "Ints1", "gene_names_refseq": "1110015K06Rik; Ints1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6P4S8", "url": "https://www.uniprot.org/uniprotkb/Q6P4S8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q6P4S8", "url": "https://www.uniprot.org/uniprotkb/Q6P4S8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "ASLSGTSALTGLTKRPKLSS", "down_seq": "PPLSALGRLAEAAVAEKRAI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q6P4S8", "url": "https://www.uniprot.org/uniprotkb/Q6P4S8" } ], "site_lbl": "Thr83" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1655", "end_pos": "1655" }, { "start_pos": "1660", "end_pos": "1660" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "859", "end_pos": "859" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "1328", "end_pos": "1328" }, { "start_pos": "1329", "end_pos": "1329" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "926", "end_pos": "926" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "Q6P4S8-1.87.87", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q6P4S8-1.87.87", "start_pos": 87, "end_pos": 87, "uniprot_canonical_ac": "Q6P4S8-1", "length": 2195, "uniprot_id": "INT1_MOUSE", "protein_name": "Integrator complex subunit 1", "refseq_ac": "NP_081024", "refseq_name": "integrator complex subunit 1", "gene_name": "Ints1", "gene_names_uniprotkb": "Ints1", "gene_names_refseq": "1110015K06Rik; Ints1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6P4S8", "url": "https://www.uniprot.org/uniprotkb/Q6P4S8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q6P4S8", "url": "https://www.uniprot.org/uniprotkb/Q6P4S8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GTSALTGLTKRPKLSSTPPL", "down_seq": "ALGRLAEAAVAEKRAISPSI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q6P4S8", "url": "https://www.uniprot.org/uniprotkb/Q6P4S8" } ], "site_lbl": "Ser87" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1655", "end_pos": "1655" }, { "start_pos": "1660", "end_pos": "1660" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "859", "end_pos": "859" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "1328", "end_pos": "1328" }, { "start_pos": "1329", "end_pos": "1329" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "926", "end_pos": "926" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "Q6P4S8-1.83.83", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q6P4S8-1.926.926", "start_pos": 926, "end_pos": 926, "uniprot_canonical_ac": "Q6P4S8-1", "length": 2195, "uniprot_id": "INT1_MOUSE", "protein_name": "Integrator complex subunit 1", "refseq_ac": "NP_081024", "refseq_name": "integrator complex subunit 1", "gene_name": "Ints1", "gene_names_uniprotkb": "Ints1", "gene_names_refseq": "1110015K06Rik; Ints1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6P4S8", "url": "https://www.uniprot.org/uniprotkb/Q6P4S8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q6P4S8", "url": "https://www.uniprot.org/uniprotkb/Q6P4S8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VLPVQCLCEFLLHDAADSTA", "down_seq": "GEEDDEGESREQKAKKRQRQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q6P4S8", "url": "https://www.uniprot.org/uniprotkb/Q6P4S8" } ], "site_lbl": "Ser926" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1655", "end_pos": "1655" }, { "start_pos": "1660", "end_pos": "1660" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "859", "end_pos": "859" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "1328", "end_pos": "1328" }, { "start_pos": "1329", "end_pos": "1329" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "926", "end_pos": "926" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.128.128", "start_pos": 128, "end_pos": 128, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs49646502", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs49646502", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "A", "start_aa": "A", "up_seq": "ADYPEGDGNWANYNTFGSAE", "down_seq": "ATSDDYKNPGYFDIQAENLG", "snv": [ { "evidence": [ { "id": "rs49646502", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs49646502" } ], "glycoeffect": [], "sequence_org": "A", "sequence_mut": "G", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171359096", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "A128", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "upstream", "id": "O88310-1.134.134", "categories": [ "snv_flag" ] }, { "distance": 15, "direction": "upstream", "id": "O88310-1.143.143", "categories": [ "snv_flag" ] }, { "distance": 20, "direction": "upstream", "id": "O88310-1.148.148", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.12.12", "start_pos": 12, "end_pos": 12, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3539924421", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3539924421", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "V", "start_aa": "V", "up_seq": "MTQLGFLLFIM", "down_seq": "ATRGCSAAEENLDTNRWGNS", "snv": [ { "evidence": [ { "id": "rs3539924421", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3539924421" } ], "glycoeffect": [], "sequence_org": "V", "sequence_mut": "I", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171362346", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "V12", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "O88310-1.5.5", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "upstream", "id": "O88310-1.14.14", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "upstream", "id": "O88310-1.16.16", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "upstream", "id": "O88310-1.17.17", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "upstream", "id": "O88310-1.22.22", "categories": [ "snv_flag" ] }, { "distance": 11, "direction": "upstream", "id": "O88310-1.23.23", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "upstream", "id": "O88310-1.25.25", "categories": [ "snv_flag" ] }, { "distance": 18, "direction": "upstream", "id": "O88310-1.30.30", "categories": [ "snv_flag" ] }, { "distance": 19, "direction": "upstream", "id": "O88310-1.31.31", "categories": [ "snv_flag" ] }, { "distance": 20, "direction": "upstream", "id": "O88310-1.32.32", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.134.134", "start_pos": 134, "end_pos": 134, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs31536500", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs31536500", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "DGNWANYNTFGSAEAATSDD", "down_seq": "KNPGYFDIQAENLGIWHVPN", "snv": [ { "evidence": [ { "id": "rs31536500", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs31536500" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "Y", "sequence_mut": "F", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171359078", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "Y134", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "O88310-1.128.128", "categories": [ "snv_flag" ] }, { "distance": 9, "direction": "upstream", "id": "O88310-1.143.143", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "upstream", "id": "O88310-1.148.148", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.143.143", "start_pos": 143, "end_pos": 143, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs1135206601", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1135206601", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "Q", "start_aa": "Q", "up_seq": "FGSAEAATSDDYKNPGYFDI", "down_seq": "AENLGIWHVPNKSPLHNWRK", "snv": [ { "evidence": [ { "id": "rs1135206601", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1135206601" } ], "glycoeffect": [], "sequence_org": "Q", "sequence_mut": "*", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171358739", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "Q143", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "O88310-1.128.128", "categories": [ "snv_flag" ] }, { "distance": 9, "direction": "downstream", "id": "O88310-1.134.134", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "upstream", "id": "O88310-1.148.148", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "upstream", "id": "O88310-1.155.155", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "upstream", "id": "O88310-1.160.160", "categories": [ "snv_flag" ] }, { "distance": 19, "direction": "upstream", "id": "O88310-1.162.162", "categories": [ "snv_flag" ] }, { "distance": 20, "direction": "upstream", "id": "O88310-1.163.163", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.148.148", "start_pos": 148, "end_pos": 148, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388515251", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388515251", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "G", "start_aa": "G", "up_seq": "AATSDDYKNPGYFDIQAENL", "down_seq": "IWHVPNKSPLHNWRKSSLLR", "snv": [ { "evidence": [ { "id": "rs3388515251", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388515251" } ], "glycoeffect": [], "sequence_org": "G", "sequence_mut": "D", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171358723", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "G148", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "O88310-1.128.128", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "downstream", "id": "O88310-1.134.134", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "downstream", "id": "O88310-1.143.143", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "upstream", "id": "O88310-1.155.155", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "upstream", "id": "O88310-1.160.160", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "upstream", "id": "O88310-1.162.162", "categories": [ "snv_flag" ] }, { "distance": 15, "direction": "upstream", "id": "O88310-1.163.163", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.14.14", "start_pos": 14, "end_pos": 14, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3539931681", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3539931681", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "MTQLGFLLFIMVA", "down_seq": "RGCSAAEENLDTNRWGNSFF", "snv": [ { "evidence": [ { "id": "rs3539931681", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3539931681" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "T", "sequence_mut": "I", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171362339", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "T14", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "O88310-1.5.5", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "downstream", "id": "O88310-1.12.12", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "upstream", "id": "O88310-1.16.16", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "upstream", "id": "O88310-1.17.17", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "upstream", "id": "O88310-1.22.22", "categories": [ "snv_flag" ] }, { "distance": 9, "direction": "upstream", "id": "O88310-1.23.23", "categories": [ "snv_flag" ] }, { "distance": 11, "direction": "upstream", "id": "O88310-1.25.25", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "upstream", "id": "O88310-1.30.30", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "upstream", "id": "O88310-1.31.31", "categories": [ "snv_flag" ] }, { "distance": 18, "direction": "upstream", "id": "O88310-1.32.32", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.155.155", "start_pos": 155, "end_pos": 155, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs1131837195", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1131837195", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "KNPGYFDIQAENLGIWHVPN", "down_seq": "SPLHNWRKSSLLRYRTFTGF", "snv": [ { "evidence": [ { "id": "rs1131837195", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1131837195" } ], "glycoeffect": [], "sequence_org": "K", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171358701", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "K155", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "O88310-1.143.143", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "downstream", "id": "O88310-1.148.148", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "upstream", "id": "O88310-1.160.160", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "upstream", "id": "O88310-1.162.162", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "upstream", "id": "O88310-1.163.163", "categories": [ "snv_flag" ] }, { "distance": 15, "direction": "upstream", "id": "O88310-1.170.170", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.160.160", "start_pos": 160, "end_pos": 160, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs1133326135", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1133326135", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "FDIQAENLGIWHVPNKSPLH", "down_seq": "WRKSSLLRYRTFTGFLQHLG", "snv": [ { "evidence": [ { "id": "rs1133326135", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1133326135" } ], "glycoeffect": [], "sequence_org": "N", "sequence_mut": "S", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171358687", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "N160", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs1133326135", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1133326135" } ], "glycoeffect": [], "sequence_org": "N", "sequence_mut": "T", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171358687", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "N160", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "O88310-1.143.143", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "downstream", "id": "O88310-1.148.148", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "downstream", "id": "O88310-1.155.155", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "upstream", "id": "O88310-1.162.162", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "upstream", "id": "O88310-1.163.163", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "upstream", "id": "O88310-1.170.170", "categories": [ "snv_flag" ] }, { "distance": 18, "direction": "upstream", "id": "O88310-1.178.178", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.162.162", "start_pos": 162, "end_pos": 162, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3539925753", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3539925753", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "IQAENLGIWHVPNKSPLHNW", "down_seq": "KSSLLRYRTFTGFLQHLGHN", "snv": [ { "evidence": [ { "id": "rs3539925753", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3539925753" } ], "glycoeffect": [], "sequence_org": "R", "sequence_mut": "K", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171358681", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "R162", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "O88310-1.143.143", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "downstream", "id": "O88310-1.148.148", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "downstream", "id": "O88310-1.155.155", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "downstream", "id": "O88310-1.160.160", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "upstream", "id": "O88310-1.163.163", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "upstream", "id": "O88310-1.170.170", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "upstream", "id": "O88310-1.178.178", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.163.163", "start_pos": 163, "end_pos": 163, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs31537348", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs31537348", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "QAENLGIWHVPNKSPLHNWR", "down_seq": "SSLLRYRTFTGFLQHLGHNL", "snv": [ { "evidence": [ { "id": "rs31537348", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs31537348" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "K", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171358677", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "K163", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "O88310-1.143.143", "categories": [ "snv_flag" ] }, { "distance": 15, "direction": "downstream", "id": "O88310-1.148.148", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "downstream", "id": "O88310-1.155.155", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "downstream", "id": "O88310-1.160.160", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "downstream", "id": "O88310-1.162.162", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "upstream", "id": "O88310-1.170.170", "categories": [ "snv_flag" ] }, { "distance": 15, "direction": "upstream", "id": "O88310-1.178.178", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.16.16", "start_pos": 16, "end_pos": 16, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3539924710", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3539924710", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "G", "start_aa": "G", "up_seq": "MTQLGFLLFIMVATR", "down_seq": "CSAAEENLDTNRWGNSFFSS", "snv": [ { "evidence": [ { "id": "rs3539924710", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3539924710" } ], "glycoeffect": [], "sequence_org": "G", "sequence_mut": "V", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171362333", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "G16", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "O88310-1.5.5", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "downstream", "id": "O88310-1.12.12", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "downstream", "id": "O88310-1.14.14", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "upstream", "id": "O88310-1.17.17", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "upstream", "id": "O88310-1.22.22", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "upstream", "id": "O88310-1.23.23", "categories": [ "snv_flag" ] }, { "distance": 9, "direction": "upstream", "id": "O88310-1.25.25", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "upstream", "id": "O88310-1.30.30", "categories": [ "snv_flag" ] }, { "distance": 15, "direction": "upstream", "id": "O88310-1.31.31", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "upstream", "id": "O88310-1.32.32", "categories": [ "snv_flag" ] }, { "distance": 19, "direction": "upstream", "id": "O88310-1.35.35", "categories": [ "snv_flag" ] }, { "distance": 20, "direction": "upstream", "id": "O88310-1.36.36", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.170.170", "start_pos": 170, "end_pos": 170, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs31569041", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs31569041", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "WHVPNKSPLHNWRKSSLLRY", "down_seq": "TFTGFLQHLGHNLFGLYKKY", "snv": [ { "evidence": [ { "id": "rs31569041", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs31569041" } ], "glycoeffect": [], "sequence_org": "R", "sequence_mut": "C", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171358658", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "R170", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "O88310-1.155.155", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "downstream", "id": "O88310-1.160.160", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "downstream", "id": "O88310-1.162.162", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "downstream", "id": "O88310-1.163.163", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "upstream", "id": "O88310-1.178.178", "categories": [ "snv_flag" ] }, { "distance": 18, "direction": "upstream", "id": "O88310-1.188.188", "categories": [ "snv_flag" ] }, { "distance": 20, "direction": "upstream", "id": "O88310-1.190.190", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.178.178", "start_pos": 178, "end_pos": 178, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs1134625814", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1134625814", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "H", "start_aa": "H", "up_seq": "LHNWRKSSLLRYRTFTGFLQ", "down_seq": "LGHNLFGLYKKYPVKYGEGK", "snv": [ { "evidence": [ { "id": "rs1134625814", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1134625814" } ], "glycoeffect": [], "sequence_org": "H", "sequence_mut": "R", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171358633", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "H178", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "O88310-1.160.160", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "downstream", "id": "O88310-1.162.162", "categories": [ "snv_flag" ] }, { "distance": 15, "direction": "downstream", "id": "O88310-1.163.163", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "downstream", "id": "O88310-1.170.170", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "upstream", "id": "O88310-1.188.188", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "upstream", "id": "O88310-1.190.190", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "upstream", "id": "O88310-1.195.195", "categories": [ "snv_flag" ] }, { "distance": 18, "direction": "upstream", "id": "O88310-1.196.196", "categories": [ "snv_flag" ] }, { "distance": 19, "direction": "upstream", "id": "O88310-1.197.197", "categories": [ "snv_flag" ] }, { "distance": 20, "direction": "upstream", "id": "O88310-1.198.198", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.17.17", "start_pos": 17, "end_pos": 17, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3539935414", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3539935414", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "C", "start_aa": "C", "up_seq": "MTQLGFLLFIMVATRG", "down_seq": "SAAEENLDTNRWGNSFFSSL", "snv": [ { "evidence": [ { "id": "rs3539935414", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3539935414" } ], "glycoeffect": [], "sequence_org": "C", "sequence_mut": "Y", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171362330", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "C17", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "O88310-1.5.5", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "downstream", "id": "O88310-1.12.12", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "downstream", "id": "O88310-1.14.14", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "downstream", "id": "O88310-1.16.16", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "upstream", "id": "O88310-1.22.22", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "upstream", "id": "O88310-1.23.23", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "upstream", "id": "O88310-1.25.25", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "upstream", "id": "O88310-1.30.30", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "upstream", "id": "O88310-1.31.31", "categories": [ "snv_flag" ] }, { "distance": 15, "direction": "upstream", "id": "O88310-1.32.32", "categories": [ "snv_flag" ] }, { "distance": 18, "direction": "upstream", "id": "O88310-1.35.35", "categories": [ "snv_flag" ] }, { "distance": 19, "direction": "upstream", "id": "O88310-1.36.36", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.188.188", "start_pos": 188, "end_pos": 188, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs1134032543", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1134032543", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "RYRTFTGFLQHLGHNLFGLY", "down_seq": "KYPVKYGEGKCWTDNGPALP", "snv": [ { "evidence": [ { "id": "rs1134032543", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1134032543" } ], "glycoeffect": [], "sequence_org": "K", "sequence_mut": "Q", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171358604", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "K188", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "O88310-1.170.170", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "downstream", "id": "O88310-1.178.178", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "upstream", "id": "O88310-1.190.190", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "upstream", "id": "O88310-1.195.195", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "upstream", "id": "O88310-1.196.196", "categories": [ "snv_flag" ] }, { "distance": 9, "direction": "upstream", "id": "O88310-1.197.197", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "upstream", "id": "O88310-1.198.198", "categories": [ "snv_flag" ] }, { "distance": 11, "direction": "upstream", "id": "O88310-1.199.199", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "upstream", "id": "O88310-1.205.205", "categories": [ "snv_flag" ] }, { "distance": 19, "direction": "upstream", "id": "O88310-1.207.207", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.190.190", "start_pos": 190, "end_pos": 190, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs1132121489", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1132121489", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "RTFTGFLQHLGHNLFGLYKK", "down_seq": "PVKYGEGKCWTDNGPALPVV", "snv": [ { "evidence": [ { "id": "rs1132121489", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1132121489" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "Y", "sequence_mut": "*", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171358177", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "Y190", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "O88310-1.170.170", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "downstream", "id": "O88310-1.178.178", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "downstream", "id": "O88310-1.188.188", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "upstream", "id": "O88310-1.195.195", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "upstream", "id": "O88310-1.196.196", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "upstream", "id": "O88310-1.197.197", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "upstream", "id": "O88310-1.198.198", "categories": [ "snv_flag" ] }, { "distance": 9, "direction": "upstream", "id": "O88310-1.199.199", "categories": [ "snv_flag" ] }, { "distance": 15, "direction": "upstream", "id": "O88310-1.205.205", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "upstream", "id": "O88310-1.207.207", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.195.195", "start_pos": 195, "end_pos": 195, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs32321038", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs32321038", "database": "dbSNP", "categories": [ "Other" ] }, { "id": "rs1132035289", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1132035289", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "G", "start_aa": "G", "up_seq": "FLQHLGHNLFGLYKKYPVKY", "down_seq": "EGKCWTDNGPALPVVYDFGD", "snv": [ { "evidence": [ { "id": "rs32321038", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs32321038" } ], "glycoeffect": [], "sequence_org": "G", "sequence_mut": "*", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171358164", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "G195", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs1132035289", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1132035289" } ], "glycoeffect": [], "sequence_org": "G", "sequence_mut": "E", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171358163", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "G195", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs32321038", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs32321038" } ], "glycoeffect": [], "sequence_org": "G", "sequence_mut": "R", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171358164", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "G195", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "O88310-1.178.178", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "downstream", "id": "O88310-1.188.188", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "downstream", "id": "O88310-1.190.190", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "upstream", "id": "O88310-1.196.196", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "upstream", "id": "O88310-1.197.197", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "upstream", "id": "O88310-1.198.198", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "upstream", "id": "O88310-1.199.199", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "upstream", "id": "O88310-1.205.205", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "upstream", "id": "O88310-1.207.207", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "upstream", "id": "O88310-1.211.211", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.196.196", "start_pos": 196, "end_pos": 196, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs1134037999", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1134037999", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "E", "start_aa": "E", "up_seq": "LQHLGHNLFGLYKKYPVKYG", "down_seq": "GKCWTDNGPALPVVYDFGDA", "snv": [ { "evidence": [ { "id": "rs1134037999", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1134037999" } ], "glycoeffect": [], "sequence_org": "E", "sequence_mut": "G", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171358160", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "E196", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs1134037999", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1134037999" } ], "glycoeffect": [], "sequence_org": "E", "sequence_mut": "V", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171358160", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "E196", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "O88310-1.178.178", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "downstream", "id": "O88310-1.188.188", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "downstream", "id": "O88310-1.190.190", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "downstream", "id": "O88310-1.195.195", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "upstream", "id": "O88310-1.197.197", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "upstream", "id": "O88310-1.198.198", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "upstream", "id": "O88310-1.199.199", "categories": [ "snv_flag" ] }, { "distance": 9, "direction": "upstream", "id": "O88310-1.205.205", "categories": [ "snv_flag" ] }, { "distance": 11, "direction": "upstream", "id": "O88310-1.207.207", "categories": [ "snv_flag" ] }, { "distance": 15, "direction": "upstream", "id": "O88310-1.211.211", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.197.197", "start_pos": 197, "end_pos": 197, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs1131856207", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1131856207", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "G", "start_aa": "G", "up_seq": "QHLGHNLFGLYKKYPVKYGE", "down_seq": "KCWTDNGPALPVVYDFGDAR", "snv": [ { "evidence": [ { "id": "rs1131856207", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1131856207" } ], "glycoeffect": [], "sequence_org": "G", "sequence_mut": "E", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171358157", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "G197", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "O88310-1.178.178", "categories": [ "snv_flag" ] }, { "distance": 9, "direction": "downstream", "id": "O88310-1.188.188", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "downstream", "id": "O88310-1.190.190", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "downstream", "id": "O88310-1.195.195", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "downstream", "id": "O88310-1.196.196", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "upstream", "id": "O88310-1.198.198", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "upstream", "id": "O88310-1.199.199", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "upstream", "id": "O88310-1.205.205", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "upstream", "id": "O88310-1.207.207", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "upstream", "id": "O88310-1.211.211", "categories": [ "snv_flag" ] }, { "distance": 20, "direction": "upstream", "id": "O88310-1.217.217", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.198.198", "start_pos": 198, "end_pos": 198, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3539928188", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3539928188", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "HLGHNLFGLYKKYPVKYGEG", "down_seq": "CWTDNGPALPVVYDFGDARK", "snv": [ { "evidence": [ { "id": "rs3539928188", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3539928188" } ], "glycoeffect": [], "sequence_org": "K", "sequence_mut": "Q", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171358155", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "K198", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "O88310-1.178.178", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "downstream", "id": "O88310-1.188.188", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "downstream", "id": "O88310-1.190.190", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "downstream", "id": "O88310-1.195.195", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "downstream", "id": "O88310-1.196.196", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "downstream", "id": "O88310-1.197.197", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "upstream", "id": "O88310-1.199.199", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "upstream", "id": "O88310-1.205.205", "categories": [ "snv_flag" ] }, { "distance": 9, "direction": "upstream", "id": "O88310-1.207.207", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "upstream", "id": "O88310-1.211.211", "categories": [ "snv_flag" ] }, { "distance": 19, "direction": "upstream", "id": "O88310-1.217.217", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.199.199", "start_pos": 199, "end_pos": 199, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs1135195454", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1135195454", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "C", "start_aa": "C", "up_seq": "LGHNLFGLYKKYPVKYGEGK", "down_seq": "WTDNGPALPVVYDFGDARKT", "snv": [ { "evidence": [ { "id": "rs1135195454", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1135195454" } ], "glycoeffect": [], "sequence_org": "C", "sequence_mut": "Y", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171358151", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "C199", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "O88310-1.188.188", "categories": [ "snv_flag" ] }, { "distance": 9, "direction": "downstream", "id": "O88310-1.190.190", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "downstream", "id": "O88310-1.195.195", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "downstream", "id": "O88310-1.196.196", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "downstream", "id": "O88310-1.197.197", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "downstream", "id": "O88310-1.198.198", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "upstream", "id": "O88310-1.205.205", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "upstream", "id": "O88310-1.207.207", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "upstream", "id": "O88310-1.211.211", "categories": [ "snv_flag" ] }, { "distance": 18, "direction": "upstream", "id": "O88310-1.217.217", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.205.205", "start_pos": 205, "end_pos": 205, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs1132931376", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1132931376", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "P", "start_aa": "P", "up_seq": "GLYKKYPVKYGEGKCWTDNG", "down_seq": "ALPVVYDFGDARKTASYYSP", "snv": [ { "evidence": [ { "id": "rs1132931376", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1132931376" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "P", "sequence_mut": "S", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171358134", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "P205", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "O88310-1.188.188", "categories": [ "snv_flag" ] }, { "distance": 15, "direction": "downstream", "id": "O88310-1.190.190", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "downstream", "id": "O88310-1.195.195", "categories": [ "snv_flag" ] }, { "distance": 9, "direction": "downstream", "id": "O88310-1.196.196", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "downstream", "id": "O88310-1.197.197", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "downstream", "id": "O88310-1.198.198", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "downstream", "id": "O88310-1.199.199", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "upstream", "id": "O88310-1.207.207", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "upstream", "id": "O88310-1.211.211", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "upstream", "id": "O88310-1.217.217", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "upstream", "id": "O88310-1.221.221", "categories": [ "snv_flag" ] }, { "distance": 19, "direction": "upstream", "id": "O88310-1.224.224", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.207.207", "start_pos": 207, "end_pos": 207, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs1132668251", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1132668251", "database": "dbSNP", "categories": [ "Other" ] }, { "id": "rs31537349", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs31537349", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "L", "start_aa": "L", "up_seq": "YKKYPVKYGEGKCWTDNGPA", "down_seq": "PVVYDFGDARKTASYYSPSG", "snv": [ { "evidence": [ { "id": "rs1132668251", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1132668251" } ], "glycoeffect": [], "sequence_org": "L", "sequence_mut": "F", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171358126", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "L207", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs31537349", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs31537349" } ], "glycoeffect": [], "sequence_org": "L", "sequence_mut": "I", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171358128", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "L207", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs31537349", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs31537349" } ], "glycoeffect": [], "sequence_org": "L", "sequence_mut": "V", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171358128", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "L207", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "O88310-1.188.188", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "downstream", "id": "O88310-1.190.190", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "downstream", "id": "O88310-1.195.195", "categories": [ "snv_flag" ] }, { "distance": 11, "direction": "downstream", "id": "O88310-1.196.196", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "downstream", "id": "O88310-1.197.197", "categories": [ "snv_flag" ] }, { "distance": 9, "direction": "downstream", "id": "O88310-1.198.198", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "downstream", "id": "O88310-1.199.199", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "downstream", "id": "O88310-1.205.205", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "upstream", "id": "O88310-1.211.211", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "upstream", "id": "O88310-1.217.217", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "upstream", "id": "O88310-1.221.221", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "upstream", "id": "O88310-1.224.224", "categories": [ "snv_flag" ] }, { "distance": 19, "direction": "upstream", "id": "O88310-1.226.226", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.211.211", "start_pos": 211, "end_pos": 211, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388513463", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388513463", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "PVKYGEGKCWTDNGPALPVV", "down_seq": "DFGDARKTASYYSPSGQREF", "snv": [ { "evidence": [ { "id": "rs3388513463", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388513463" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "Y", "sequence_mut": "H", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171358116", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "Y211", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "O88310-1.195.195", "categories": [ "snv_flag" ] }, { "distance": 15, "direction": "downstream", "id": "O88310-1.196.196", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "downstream", "id": "O88310-1.197.197", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "downstream", "id": "O88310-1.198.198", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "downstream", "id": "O88310-1.199.199", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "downstream", "id": "O88310-1.205.205", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "downstream", "id": "O88310-1.207.207", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "upstream", "id": "O88310-1.217.217", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "upstream", "id": "O88310-1.221.221", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "upstream", "id": "O88310-1.224.224", "categories": [ "snv_flag" ] }, { "distance": 15, "direction": "upstream", "id": "O88310-1.226.226", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "upstream", "id": "O88310-1.228.228", "categories": [ "snv_flag" ] }, { "distance": 18, "direction": "upstream", "id": "O88310-1.229.229", "categories": [ "snv_flag" ] }, { "distance": 19, "direction": "upstream", "id": "O88310-1.230.230", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.217.217", "start_pos": 217, "end_pos": 217, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs581378716", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs581378716", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "GKCWTDNGPALPVVYDFGDA", "down_seq": "KTASYYSPSGQREFTAGYVQ", "snv": [ { "evidence": [ { "id": "rs581378716", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs581378716" } ], "glycoeffect": [], "sequence_org": "R", "sequence_mut": "Q", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171358097", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "R217", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "O88310-1.197.197", "categories": [ "snv_flag" ] }, { "distance": 19, "direction": "downstream", "id": "O88310-1.198.198", "categories": [ "snv_flag" ] }, { "distance": 18, "direction": "downstream", "id": "O88310-1.199.199", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "downstream", "id": "O88310-1.205.205", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "downstream", "id": "O88310-1.207.207", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "downstream", "id": "O88310-1.211.211", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "upstream", "id": "O88310-1.221.221", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "upstream", "id": "O88310-1.224.224", "categories": [ "snv_flag" ] }, { "distance": 9, "direction": "upstream", "id": "O88310-1.226.226", "categories": [ "snv_flag" ] }, { "distance": 11, "direction": "upstream", "id": "O88310-1.228.228", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "upstream", "id": "O88310-1.229.229", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "upstream", "id": "O88310-1.230.230", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.221.221", "start_pos": 221, "end_pos": 221, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs32796948", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs32796948", "database": "dbSNP", "categories": [ "Other" ] }, { "id": "rs1134534402", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1134534402", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TDNGPALPVVYDFGDARKTA", "down_seq": "YYSPSGQREFTAGYVQFRVF", "snv": [ { "evidence": [ { "id": "rs32796948", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs32796948" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "S", "sequence_mut": "A", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171358086", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S221", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs1134534402", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1134534402" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "S", "sequence_mut": "F", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171358085", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S221", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "O88310-1.205.205", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "downstream", "id": "O88310-1.207.207", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "downstream", "id": "O88310-1.211.211", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "downstream", "id": "O88310-1.217.217", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "upstream", "id": "O88310-1.224.224", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "upstream", "id": "O88310-1.226.226", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "upstream", "id": "O88310-1.228.228", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "upstream", "id": "O88310-1.229.229", "categories": [ "snv_flag" ] }, { "distance": 9, "direction": "upstream", "id": "O88310-1.230.230", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.224.224", "start_pos": 224, "end_pos": 224, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388516670", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388516670", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GPALPVVYDFGDARKTASYY", "down_seq": "PSGQREFTAGYVQFRVFNNE", "snv": [ { "evidence": [ { "id": "rs3388516670", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388516670" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "S", "sequence_mut": "F", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171358076", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S224", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "O88310-1.205.205", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "downstream", "id": "O88310-1.207.207", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "downstream", "id": "O88310-1.211.211", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "downstream", "id": "O88310-1.217.217", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "downstream", "id": "O88310-1.221.221", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "upstream", "id": "O88310-1.226.226", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "upstream", "id": "O88310-1.228.228", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "upstream", "id": "O88310-1.229.229", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "upstream", "id": "O88310-1.230.230", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.226.226", "start_pos": 226, "end_pos": 226, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs1135325889", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1135325889", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ALPVVYDFGDARKTASYYSP", "down_seq": "GQREFTAGYVQFRVFNNERA", "snv": [ { "evidence": [ { "id": "rs1135325889", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1135325889" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "S", "sequence_mut": "C", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171358070", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S226", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs1135325889", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1135325889" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "S", "sequence_mut": "Y", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171358070", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S226", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "O88310-1.207.207", "categories": [ "snv_flag" ] }, { "distance": 15, "direction": "downstream", "id": "O88310-1.211.211", "categories": [ "snv_flag" ] }, { "distance": 9, "direction": "downstream", "id": "O88310-1.217.217", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "downstream", "id": "O88310-1.221.221", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "downstream", "id": "O88310-1.224.224", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "upstream", "id": "O88310-1.228.228", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "upstream", "id": "O88310-1.229.229", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "upstream", "id": "O88310-1.230.230", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.228.228", "start_pos": 228, "end_pos": 228, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs1133651885", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1133651885", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "Q", "start_aa": "Q", "up_seq": "PVVYDFGDARKTASYYSPSG", "down_seq": "REFTAGYVQFRVFNNERAAS", "snv": [ { "evidence": [ { "id": "rs1133651885", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1133651885" } ], "glycoeffect": [], "sequence_org": "Q", "sequence_mut": "R", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171358064", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "Q228", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "O88310-1.211.211", "categories": [ "snv_flag" ] }, { "distance": 11, "direction": "downstream", "id": "O88310-1.217.217", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "downstream", "id": "O88310-1.221.221", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "downstream", "id": "O88310-1.224.224", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "downstream", "id": "O88310-1.226.226", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "upstream", "id": "O88310-1.229.229", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "upstream", "id": "O88310-1.230.230", "categories": [ "snv_flag" ] }, { "distance": 19, "direction": "upstream", "id": "O88310-1.247.247", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.229.229", "start_pos": 229, "end_pos": 229, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs1132153449", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1132153449", "database": "dbSNP", "categories": [ "Other" ] }, { "id": "rs1134157791", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1134157791", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "VVYDFGDARKTASYYSPSGQ", "down_seq": "EFTAGYVQFRVFNNERAASA", "snv": [ { "evidence": [ { "id": "rs1132153449", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1132153449" } ], "glycoeffect": [], "sequence_org": "R", "sequence_mut": "K", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171356792", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "R229", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs1132153449", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1132153449" } ], "glycoeffect": [], "sequence_org": "R", "sequence_mut": "M", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171356792", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "R229", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs1134157791", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1134157791" } ], "glycoeffect": [], "sequence_org": "R", "sequence_mut": "S", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171356791", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "R229", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "O88310-1.211.211", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "downstream", "id": "O88310-1.217.217", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "downstream", "id": "O88310-1.221.221", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "downstream", "id": "O88310-1.224.224", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "downstream", "id": "O88310-1.226.226", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "downstream", "id": "O88310-1.228.228", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "upstream", "id": "O88310-1.230.230", "categories": [ "snv_flag" ] }, { "distance": 18, "direction": "upstream", "id": "O88310-1.247.247", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.22.22", "start_pos": 22, "end_pos": 22, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3390903390", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3390903390", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "E", "start_aa": "E", "up_seq": "TQLGFLLFIMVATRGCSAAE", "down_seq": "NLDTNRWGNSFFSSLPRSCK", "snv": [ { "evidence": [ { "id": "rs3390903390", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3390903390" } ], "glycoeffect": [], "sequence_org": "E", "sequence_mut": "K", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171361027", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "E22", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "O88310-1.5.5", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "downstream", "id": "O88310-1.12.12", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "downstream", "id": "O88310-1.14.14", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "downstream", "id": "O88310-1.16.16", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "downstream", "id": "O88310-1.17.17", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "upstream", "id": "O88310-1.23.23", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "upstream", "id": "O88310-1.25.25", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "upstream", "id": "O88310-1.30.30", "categories": [ "snv_flag" ] }, { "distance": 9, "direction": "upstream", "id": "O88310-1.31.31", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "upstream", "id": "O88310-1.32.32", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "upstream", "id": "O88310-1.35.35", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "upstream", "id": "O88310-1.36.36", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "upstream", "id": "O88310-1.39.39", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.230.230", "start_pos": 230, "end_pos": 230, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs1135327036", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1135327036", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "E", "start_aa": "E", "up_seq": "VYDFGDARKTASYYSPSGQR", "down_seq": "FTAGYVQFRVFNNERAASAL", "snv": [ { "evidence": [ { "id": "rs1135327036", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1135327036" } ], "glycoeffect": [], "sequence_org": "E", "sequence_mut": "Q", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171356790", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "E230", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "O88310-1.211.211", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "downstream", "id": "O88310-1.217.217", "categories": [ "snv_flag" ] }, { "distance": 9, "direction": "downstream", "id": "O88310-1.221.221", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "downstream", "id": "O88310-1.224.224", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "downstream", "id": "O88310-1.226.226", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "downstream", "id": "O88310-1.228.228", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "downstream", "id": "O88310-1.229.229", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "upstream", "id": "O88310-1.247.247", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.23.23", "start_pos": 23, "end_pos": 23, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388516708", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388516708", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "QLGFLLFIMVATRGCSAAEE", "down_seq": "LDTNRWGNSFFSSLPRSCKE", "snv": [ { "evidence": [ { "id": "rs3388516708", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388516708" } ], "glycoeffect": [], "sequence_org": "N", "sequence_mut": "D", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171361024", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "N23", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "O88310-1.5.5", "categories": [ "snv_flag" ] }, { "distance": 11, "direction": "downstream", "id": "O88310-1.12.12", "categories": [ "snv_flag" ] }, { "distance": 9, "direction": "downstream", "id": "O88310-1.14.14", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "downstream", "id": "O88310-1.16.16", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "downstream", "id": "O88310-1.17.17", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "downstream", "id": "O88310-1.22.22", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "upstream", "id": "O88310-1.25.25", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "upstream", "id": "O88310-1.30.30", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "upstream", "id": "O88310-1.31.31", "categories": [ "snv_flag" ] }, { "distance": 9, "direction": "upstream", "id": "O88310-1.32.32", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "upstream", "id": "O88310-1.35.35", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "upstream", "id": "O88310-1.36.36", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "upstream", "id": "O88310-1.39.39", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.247.247", "start_pos": 247, "end_pos": 247, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3539935357", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3539935357", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "A", "start_aa": "A", "up_seq": "GQREFTAGYVQFRVFNNERA", "down_seq": "SALCAGVRVTGCNTEHHCIG", "snv": [ { "evidence": [ { "id": "rs3539935357", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3539935357" } ], "glycoeffect": [], "sequence_org": "A", "sequence_mut": "V", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171356738", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "A247", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "O88310-1.228.228", "categories": [ "snv_flag" ] }, { "distance": 18, "direction": "downstream", "id": "O88310-1.229.229", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "downstream", "id": "O88310-1.230.230", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "upstream", "id": "O88310-1.254.254", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "upstream", "id": "O88310-1.255.255", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "upstream", "id": "O88310-1.260.260", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "upstream", "id": "O88310-1.261.261", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "upstream", "id": "O88310-1.263.263", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.254.254", "start_pos": 254, "end_pos": 254, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs1132957496", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1132957496", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "V", "start_aa": "V", "up_seq": "GYVQFRVFNNERAASALCAG", "down_seq": "RVTGCNTEHHCIGGGGFFPE", "snv": [ { "evidence": [ { "id": "rs1132957496", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1132957496" } ], "glycoeffect": [], "sequence_org": "V", "sequence_mut": "M", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171356718", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "V254", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "O88310-1.247.247", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "upstream", "id": "O88310-1.255.255", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "upstream", "id": "O88310-1.260.260", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "upstream", "id": "O88310-1.261.261", "categories": [ "snv_flag" ] }, { "distance": 9, "direction": "upstream", "id": "O88310-1.263.263", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.255.255", "start_pos": 255, "end_pos": 255, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs1134593128", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1134593128", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "YVQFRVFNNERAASALCAGV", "down_seq": "VTGCNTEHHCIGGGGFFPEG", "snv": [ { "evidence": [ { "id": "rs1134593128", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1134593128" } ], "glycoeffect": [], "sequence_org": "R", "sequence_mut": "K", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171356714", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "R255", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "O88310-1.247.247", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "downstream", "id": "O88310-1.254.254", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "upstream", "id": "O88310-1.260.260", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "upstream", "id": "O88310-1.261.261", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "upstream", "id": "O88310-1.263.263", "categories": [ "snv_flag" ] }, { "distance": 20, "direction": "upstream", "id": "O88310-1.275.275", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.25.25", "start_pos": 25, "end_pos": 25, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3390903410", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3390903410", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "GFLLFIMVATRGCSAAEENL", "down_seq": "TNRWGNSFFSSLPRSCKEIK", "snv": [ { "evidence": [ { "id": "rs3390903410", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3390903410" } ], "glycoeffect": [], "sequence_org": "D", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171361018", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "D25", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs3390903410", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3390903410" } ], "glycoeffect": [], "sequence_org": "D", "sequence_mut": "Y", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171361018", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "D25", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "O88310-1.5.5", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "downstream", "id": "O88310-1.12.12", "categories": [ "snv_flag" ] }, { "distance": 11, "direction": "downstream", "id": "O88310-1.14.14", "categories": [ "snv_flag" ] }, { "distance": 9, "direction": "downstream", "id": "O88310-1.16.16", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "downstream", "id": "O88310-1.17.17", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "downstream", "id": "O88310-1.22.22", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "downstream", "id": "O88310-1.23.23", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "upstream", "id": "O88310-1.30.30", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "upstream", "id": "O88310-1.31.31", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "upstream", "id": "O88310-1.32.32", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "upstream", "id": "O88310-1.35.35", "categories": [ "snv_flag" ] }, { "distance": 11, "direction": "upstream", "id": "O88310-1.36.36", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "upstream", "id": "O88310-1.39.39", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.260.260", "start_pos": 260, "end_pos": 260, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs1134337631", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1134337631", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "VFNNERAASALCAGVRVTGC", "down_seq": "TEHHCIGGGGFFPEGNPVQC", "snv": [ { "evidence": [ { "id": "rs1134337631", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1134337631" } ], "glycoeffect": [], "sequence_org": "N", "sequence_mut": "D", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171356700", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "N260", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "O88310-1.247.247", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "downstream", "id": "O88310-1.254.254", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "downstream", "id": "O88310-1.255.255", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "upstream", "id": "O88310-1.261.261", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "upstream", "id": "O88310-1.263.263", "categories": [ "snv_flag" ] }, { "distance": 15, "direction": "upstream", "id": "O88310-1.275.275", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "upstream", "id": "O88310-1.276.276", "categories": [ "snv_flag" ] }, { "distance": 18, "direction": "upstream", "id": "O88310-1.278.278", "categories": [ "snv_flag" ] }, { "distance": 19, "direction": "upstream", "id": "O88310-1.279.279", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.261.261", "start_pos": 261, "end_pos": 261, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3390995981", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3390995981", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "FNNERAASALCAGVRVTGCN", "down_seq": "EHHCIGGGGFFPEGNPVQCG", "snv": [ { "evidence": [ { "id": "rs3390995981", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3390995981" } ], "glycoeffect": [], "sequence_org": "T", "sequence_mut": "S", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171356697", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "T261", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "O88310-1.247.247", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "downstream", "id": "O88310-1.254.254", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "downstream", "id": "O88310-1.255.255", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "downstream", "id": "O88310-1.260.260", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "upstream", "id": "O88310-1.263.263", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "upstream", "id": "O88310-1.275.275", "categories": [ "snv_flag" ] }, { "distance": 15, "direction": "upstream", "id": "O88310-1.276.276", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "upstream", "id": "O88310-1.278.278", "categories": [ "snv_flag" ] }, { "distance": 18, "direction": "upstream", "id": "O88310-1.279.279", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.263.263", "start_pos": 263, "end_pos": 263, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs1132753260", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1132753260", "database": "dbSNP", "categories": [ "Other" ] }, { "id": "rs3390949845", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3390949845", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "H", "start_aa": "H", "up_seq": "NERAASALCAGVRVTGCNTE", "down_seq": "HCIGGGGFFPEGNPVQCGDF", "snv": [ { "evidence": [ { "id": "rs1132753260", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1132753260" } ], "glycoeffect": [], "sequence_org": "H", "sequence_mut": "D", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171356691", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "H263", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs3390949845", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3390949845" } ], "glycoeffect": [], "sequence_org": "H", "sequence_mut": "P", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171356690", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "H263", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs1132753260", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1132753260" } ], "glycoeffect": [], "sequence_org": "H", "sequence_mut": "Y", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171356691", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "H263", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "O88310-1.247.247", "categories": [ "snv_flag" ] }, { "distance": 9, "direction": "downstream", "id": "O88310-1.254.254", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "downstream", "id": "O88310-1.255.255", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "downstream", "id": "O88310-1.260.260", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "downstream", "id": "O88310-1.261.261", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "upstream", "id": "O88310-1.275.275", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "upstream", "id": "O88310-1.276.276", "categories": [ "snv_flag" ] }, { "distance": 15, "direction": "upstream", "id": "O88310-1.278.278", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "upstream", "id": "O88310-1.279.279", "categories": [ "snv_flag" ] }, { "distance": 19, "direction": "upstream", "id": "O88310-1.282.282", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.275.275", "start_pos": 275, "end_pos": 275, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs1134502245", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1134502245", "database": "dbSNP", "categories": [ "Other" ] }, { "id": "rs1131745197", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1131745197", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "G", "start_aa": "G", "up_seq": "RVTGCNTEHHCIGGGGFFPE", "down_seq": "NPVQCGDFASFDWDGYGTHN", "snv": [ { "evidence": [ { "id": "rs1134502245", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1134502245" } ], "glycoeffect": [], "sequence_org": "G", "sequence_mut": "C", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171345928", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "G275", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs1134502245", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1134502245" } ], "glycoeffect": [], "sequence_org": "G", "sequence_mut": "S", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171345928", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "G275", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs1131745197", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1131745197" } ], "glycoeffect": [], "sequence_org": "G", "sequence_mut": "V", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171345927", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "G275", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "O88310-1.255.255", "categories": [ "snv_flag" ] }, { "distance": 15, "direction": "downstream", "id": "O88310-1.260.260", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "downstream", "id": "O88310-1.261.261", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "downstream", "id": "O88310-1.263.263", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "upstream", "id": "O88310-1.276.276", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "upstream", "id": "O88310-1.278.278", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "upstream", "id": "O88310-1.279.279", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "upstream", "id": "O88310-1.282.282", "categories": [ "snv_flag" ] }, { "distance": 9, "direction": "upstream", "id": "O88310-1.284.284", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "upstream", "id": "O88310-1.285.285", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "upstream", "id": "O88310-1.288.288", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "upstream", "id": "O88310-1.289.289", "categories": [ "snv_flag" ] }, { "distance": 20, "direction": "upstream", "id": "O88310-1.295.295", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.276.276", "start_pos": 276, "end_pos": 276, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs1132830708", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1132830708", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "VTGCNTEHHCIGGGGFFPEG", "down_seq": "PVQCGDFASFDWDGYGTHNG", "snv": [ { "evidence": [ { "id": "rs1132830708", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1132830708" } ], "glycoeffect": [], "sequence_org": "N", "sequence_mut": "D", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171345925", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "N276", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs1132830708", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1132830708" } ], "glycoeffect": [], "sequence_org": "N", "sequence_mut": "Y", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171345925", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "N276", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "O88310-1.260.260", "categories": [ "snv_flag" ] }, { "distance": 15, "direction": "downstream", "id": "O88310-1.261.261", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "downstream", "id": "O88310-1.263.263", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "downstream", "id": "O88310-1.275.275", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "upstream", "id": "O88310-1.278.278", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "upstream", "id": "O88310-1.279.279", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "upstream", "id": "O88310-1.282.282", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "upstream", "id": "O88310-1.284.284", "categories": [ "snv_flag" ] }, { "distance": 9, "direction": "upstream", "id": "O88310-1.285.285", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "upstream", "id": "O88310-1.288.288", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "upstream", "id": "O88310-1.289.289", "categories": [ "snv_flag" ] }, { "distance": 19, "direction": "upstream", "id": "O88310-1.295.295", "categories": [ "snv_flag" ] }, { "distance": 20, "direction": "upstream", "id": "O88310-1.296.296", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.278.278", "start_pos": 278, "end_pos": 278, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs1134926256", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1134926256", "database": "dbSNP", "categories": [ "Other" ] }, { "id": "rs1134500334", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1134500334", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "V", "start_aa": "V", "up_seq": "GCNTEHHCIGGGGFFPEGNP", "down_seq": "QCGDFASFDWDGYGTHNGYS", "snv": [ { "evidence": [ { "id": "rs1134926256", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1134926256" } ], "glycoeffect": [], "sequence_org": "V", "sequence_mut": "E", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171345918", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "V278", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs1134500334", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1134500334" } ], "glycoeffect": [], "sequence_org": "V", "sequence_mut": "L", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171345919", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "V278", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs1134500334", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1134500334" } ], "glycoeffect": [], "sequence_org": "V", "sequence_mut": "M", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171345919", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "V278", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "O88310-1.260.260", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "downstream", "id": "O88310-1.261.261", "categories": [ "snv_flag" ] }, { "distance": 15, "direction": "downstream", "id": "O88310-1.263.263", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "downstream", "id": "O88310-1.275.275", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "downstream", "id": "O88310-1.276.276", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "upstream", "id": "O88310-1.279.279", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "upstream", "id": "O88310-1.282.282", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "upstream", "id": "O88310-1.284.284", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "upstream", "id": "O88310-1.285.285", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "upstream", "id": "O88310-1.288.288", "categories": [ "snv_flag" ] }, { "distance": 11, "direction": "upstream", "id": "O88310-1.289.289", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "upstream", "id": "O88310-1.295.295", "categories": [ "snv_flag" ] }, { "distance": 18, "direction": "upstream", "id": "O88310-1.296.296", "categories": [ "snv_flag" ] }, { "distance": 19, "direction": "upstream", "id": "O88310-1.297.297", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.279.279", "start_pos": 279, "end_pos": 279, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs1132067468", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1132067468", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "Q", "start_aa": "Q", "up_seq": "CNTEHHCIGGGGFFPEGNPV", "down_seq": "CGDFASFDWDGYGTHNGYSS", "snv": [ { "evidence": [ { "id": "rs1132067468", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1132067468" } ], "glycoeffect": [], "sequence_org": "Q", "sequence_mut": "E", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171345916", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "Q279", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "O88310-1.260.260", "categories": [ "snv_flag" ] }, { "distance": 18, "direction": "downstream", "id": "O88310-1.261.261", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "downstream", "id": "O88310-1.263.263", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "downstream", "id": "O88310-1.275.275", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "downstream", "id": "O88310-1.276.276", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "downstream", "id": "O88310-1.278.278", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "upstream", "id": "O88310-1.282.282", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "upstream", "id": "O88310-1.284.284", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "upstream", "id": "O88310-1.285.285", "categories": [ "snv_flag" ] }, { "distance": 9, "direction": "upstream", "id": "O88310-1.288.288", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "upstream", "id": "O88310-1.289.289", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "upstream", "id": "O88310-1.295.295", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "upstream", "id": "O88310-1.296.296", "categories": [ "snv_flag" ] }, { "distance": 18, "direction": "upstream", "id": "O88310-1.297.297", "categories": [ "snv_flag" ] }, { "distance": 20, "direction": "upstream", "id": "O88310-1.299.299", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.282.282", "start_pos": 282, "end_pos": 282, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388516245", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388516245", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "EHHCIGGGGFFPEGNPVQCG", "down_seq": "FASFDWDGYGTHNGYSSSRK", "snv": [ { "evidence": [ { "id": "rs3388516245", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388516245" } ], "glycoeffect": [], "sequence_org": "D", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171345907", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "D282", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "O88310-1.263.263", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "downstream", "id": "O88310-1.275.275", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "downstream", "id": "O88310-1.276.276", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "downstream", "id": "O88310-1.278.278", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "downstream", "id": "O88310-1.279.279", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "upstream", "id": "O88310-1.284.284", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "upstream", "id": "O88310-1.285.285", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "upstream", "id": "O88310-1.288.288", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "upstream", "id": "O88310-1.289.289", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "upstream", "id": "O88310-1.295.295", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "upstream", "id": "O88310-1.296.296", "categories": [ "snv_flag" ] }, { "distance": 15, "direction": "upstream", "id": "O88310-1.297.297", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "upstream", "id": "O88310-1.299.299", "categories": [ "snv_flag" ] }, { "distance": 19, "direction": "upstream", "id": "O88310-1.301.301", "categories": [ "snv_flag" ] }, { "distance": 20, "direction": "upstream", "id": "O88310-1.302.302", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.284.284", "start_pos": 284, "end_pos": 284, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3539934700", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3539934700", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "A", "start_aa": "A", "up_seq": "HCIGGGGFFPEGNPVQCGDF", "down_seq": "SFDWDGYGTHNGYSSSRKIT", "snv": [ { "evidence": [ { "id": "rs3539934700", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3539934700" } ], "glycoeffect": [], "sequence_org": "A", "sequence_mut": "G", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171345900", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "A284", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "O88310-1.275.275", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "downstream", "id": "O88310-1.276.276", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "downstream", "id": "O88310-1.278.278", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "downstream", "id": "O88310-1.279.279", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "downstream", "id": "O88310-1.282.282", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "upstream", "id": "O88310-1.285.285", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "upstream", "id": "O88310-1.288.288", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "upstream", "id": "O88310-1.289.289", "categories": [ "snv_flag" ] }, { "distance": 11, "direction": "upstream", "id": "O88310-1.295.295", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "upstream", "id": "O88310-1.296.296", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "upstream", "id": "O88310-1.297.297", "categories": [ "snv_flag" ] }, { "distance": 15, "direction": "upstream", "id": "O88310-1.299.299", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "upstream", "id": "O88310-1.301.301", "categories": [ "snv_flag" ] }, { "distance": 18, "direction": "upstream", "id": "O88310-1.302.302", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.285.285", "start_pos": 285, "end_pos": 285, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs1134496167", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1134496167", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "CIGGGGFFPEGNPVQCGDFA", "down_seq": "FDWDGYGTHNGYSSSRKITE", "snv": [ { "evidence": [ { "id": "rs1134496167", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1134496167" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "S", "sequence_mut": "A", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171345898", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S285", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "O88310-1.275.275", "categories": [ "snv_flag" ] }, { "distance": 9, "direction": "downstream", "id": "O88310-1.276.276", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "downstream", "id": "O88310-1.278.278", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "downstream", "id": "O88310-1.279.279", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "downstream", "id": "O88310-1.282.282", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "downstream", "id": "O88310-1.284.284", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "upstream", "id": "O88310-1.288.288", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "upstream", "id": "O88310-1.289.289", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "upstream", "id": "O88310-1.295.295", "categories": [ "snv_flag" ] }, { "distance": 11, "direction": "upstream", "id": "O88310-1.296.296", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "upstream", "id": "O88310-1.297.297", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "upstream", "id": "O88310-1.299.299", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "upstream", "id": "O88310-1.301.301", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "upstream", "id": "O88310-1.302.302", "categories": [ "snv_flag" ] }, { "distance": 20, "direction": "upstream", "id": "O88310-1.305.305", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.288.288", "start_pos": 288, "end_pos": 288, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs1134279251", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1134279251", "database": "dbSNP", "categories": [ "Other" ] }, { "id": "rs1133015987", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1133015987", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "W", "start_aa": "W", "up_seq": "GGGFFPEGNPVQCGDFASFD", "down_seq": "DGYGTHNGYSSSRKITEAAV", "snv": [ { "evidence": [ { "id": "rs1134279251", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1134279251" } ], "glycoeffect": [], "sequence_org": "W", "sequence_mut": "G", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171345889", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "W288", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs1133015987", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1133015987" } ], "glycoeffect": [], "sequence_org": "W", "sequence_mut": "S", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171345888", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "W288", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "O88310-1.275.275", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "downstream", "id": "O88310-1.276.276", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "downstream", "id": "O88310-1.278.278", "categories": [ "snv_flag" ] }, { "distance": 9, "direction": "downstream", "id": "O88310-1.279.279", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "downstream", "id": "O88310-1.282.282", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "downstream", "id": "O88310-1.284.284", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "downstream", "id": "O88310-1.285.285", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "upstream", "id": "O88310-1.289.289", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "upstream", "id": "O88310-1.295.295", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "upstream", "id": "O88310-1.296.296", "categories": [ "snv_flag" ] }, { "distance": 9, "direction": "upstream", "id": "O88310-1.297.297", "categories": [ "snv_flag" ] }, { "distance": 11, "direction": "upstream", "id": "O88310-1.299.299", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "upstream", "id": "O88310-1.301.301", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "upstream", "id": "O88310-1.302.302", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "upstream", "id": "O88310-1.305.305", "categories": [ "snv_flag" ] }, { "distance": 19, "direction": "upstream", "id": "O88310-1.307.307", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.289.289", "start_pos": 289, "end_pos": 289, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs585682349", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs585682349", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "GGFFPEGNPVQCGDFASFDW", "down_seq": "GYGTHNGYSSSRKITEAAVL", "snv": [ { "evidence": [ { "id": "rs585682349", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs585682349" } ], "glycoeffect": [], "sequence_org": "D", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171345886", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "D289", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "O88310-1.275.275", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "downstream", "id": "O88310-1.276.276", "categories": [ "snv_flag" ] }, { "distance": 11, "direction": "downstream", "id": "O88310-1.278.278", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "downstream", "id": "O88310-1.279.279", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "downstream", "id": "O88310-1.282.282", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "downstream", "id": "O88310-1.284.284", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "downstream", "id": "O88310-1.285.285", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "downstream", "id": "O88310-1.288.288", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "upstream", "id": "O88310-1.295.295", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "upstream", "id": "O88310-1.296.296", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "upstream", "id": "O88310-1.297.297", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "upstream", "id": "O88310-1.299.299", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "upstream", "id": "O88310-1.301.301", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "upstream", "id": "O88310-1.302.302", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "upstream", "id": "O88310-1.305.305", "categories": [ "snv_flag" ] }, { "distance": 18, "direction": "upstream", "id": "O88310-1.307.307", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.295.295", "start_pos": 295, "end_pos": 295, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs108800720", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs108800720", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "GNPVQCGDFASFDWDGYGTH", "down_seq": "GYSSSRKITEAAVLLFYR", "snv": [ { "evidence": [ { "id": "rs108800720", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs108800720" } ], "glycoeffect": [], "sequence_org": "N", "sequence_mut": "I", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171345867", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "N295", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs108800720", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs108800720" } ], "glycoeffect": [], "sequence_org": "N", "sequence_mut": "T", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171345867", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "N295", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "O88310-1.275.275", "categories": [ "snv_flag" ] }, { "distance": 19, "direction": "downstream", "id": "O88310-1.276.276", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "downstream", "id": "O88310-1.278.278", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "downstream", "id": "O88310-1.279.279", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "downstream", "id": "O88310-1.282.282", "categories": [ "snv_flag" ] }, { "distance": 11, "direction": "downstream", "id": "O88310-1.284.284", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "downstream", "id": "O88310-1.285.285", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "downstream", "id": "O88310-1.288.288", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "downstream", "id": "O88310-1.289.289", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "upstream", "id": "O88310-1.296.296", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "upstream", "id": "O88310-1.297.297", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "upstream", "id": "O88310-1.299.299", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "upstream", "id": "O88310-1.301.301", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "upstream", "id": "O88310-1.302.302", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "upstream", "id": "O88310-1.305.305", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "upstream", "id": "O88310-1.307.307", "categories": [ "snv_flag" ] }, { "distance": 18, "direction": "upstream", "id": "O88310-1.313.313", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.296.296", "start_pos": 296, "end_pos": 296, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs32754554", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs32754554", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "G", "start_aa": "G", "up_seq": "NPVQCGDFASFDWDGYGTHN", "down_seq": "YSSSRKITEAAVLLFYR", "snv": [ { "evidence": [ { "id": "rs32754554", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs32754554" } ], "glycoeffect": [], "sequence_org": "G", "sequence_mut": "R", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171345865", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "G296", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs32754554", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs32754554" } ], "glycoeffect": [], "sequence_org": "G", "sequence_mut": "W", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171345865", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "G296", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "O88310-1.276.276", "categories": [ "snv_flag" ] }, { "distance": 18, "direction": "downstream", "id": "O88310-1.278.278", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "downstream", "id": "O88310-1.279.279", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "downstream", "id": "O88310-1.282.282", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "downstream", "id": "O88310-1.284.284", "categories": [ "snv_flag" ] }, { "distance": 11, "direction": "downstream", "id": "O88310-1.285.285", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "downstream", "id": "O88310-1.288.288", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "downstream", "id": "O88310-1.289.289", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "downstream", "id": "O88310-1.295.295", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "upstream", "id": "O88310-1.297.297", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "upstream", "id": "O88310-1.299.299", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "upstream", "id": "O88310-1.301.301", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "upstream", "id": "O88310-1.302.302", "categories": [ "snv_flag" ] }, { "distance": 9, "direction": "upstream", "id": "O88310-1.305.305", "categories": [ "snv_flag" ] }, { "distance": 11, "direction": "upstream", "id": "O88310-1.307.307", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "upstream", "id": "O88310-1.313.313", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.297.297", "start_pos": 297, "end_pos": 297, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs33860167", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs33860167", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "PVQCGDFASFDWDGYGTHNG", "down_seq": "SSSRKITEAAVLLFYR", "snv": [ { "evidence": [ { "id": "rs33860167", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs33860167" } ], "glycoeffect": [ "n-glyco-sequon-gain", "o-glyco-site-loss" ], "sequence_org": "Y", "sequence_mut": "C", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171345861", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "Y297", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs33860167", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs33860167" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "Y", "sequence_mut": "F", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171345861", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "Y297", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "O88310-1.278.278", "categories": [ "snv_flag" ] }, { "distance": 18, "direction": "downstream", "id": "O88310-1.279.279", "categories": [ "snv_flag" ] }, { "distance": 15, "direction": "downstream", "id": "O88310-1.282.282", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "downstream", "id": "O88310-1.284.284", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "downstream", "id": "O88310-1.285.285", "categories": [ "snv_flag" ] }, { "distance": 9, "direction": "downstream", "id": "O88310-1.288.288", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "downstream", "id": "O88310-1.289.289", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "downstream", "id": "O88310-1.295.295", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "downstream", "id": "O88310-1.296.296", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "upstream", "id": "O88310-1.299.299", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "upstream", "id": "O88310-1.301.301", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "upstream", "id": "O88310-1.302.302", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "upstream", "id": "O88310-1.305.305", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "upstream", "id": "O88310-1.307.307", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "upstream", "id": "O88310-1.313.313", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.299.299", "start_pos": 299, "end_pos": 299, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs1132063484", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1132063484", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QCGDFASFDWDGYGTHNGYS", "down_seq": "SRKITEAAVLLFYR", "snv": [ { "evidence": [ { "id": "rs1132063484", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1132063484" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "S", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171345855", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S299", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "O88310-1.279.279", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "downstream", "id": "O88310-1.282.282", "categories": [ "snv_flag" ] }, { "distance": 15, "direction": "downstream", "id": "O88310-1.284.284", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "downstream", "id": "O88310-1.285.285", "categories": [ "snv_flag" ] }, { "distance": 11, "direction": "downstream", "id": "O88310-1.288.288", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "downstream", "id": "O88310-1.289.289", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "downstream", "id": "O88310-1.295.295", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "downstream", "id": "O88310-1.296.296", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "downstream", "id": "O88310-1.297.297", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "upstream", "id": "O88310-1.301.301", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "upstream", "id": "O88310-1.302.302", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "upstream", "id": "O88310-1.305.305", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "upstream", "id": "O88310-1.307.307", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "upstream", "id": "O88310-1.313.313", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.301.301", "start_pos": 301, "end_pos": 301, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs1131735668", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1131735668", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "GDFASFDWDGYGTHNGYSSS", "down_seq": "KITEAAVLLFYR", "snv": [ { "evidence": [ { "id": "rs1131735668", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1131735668" } ], "glycoeffect": [], "sequence_org": "R", "sequence_mut": "Q", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171345849", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "R301", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "O88310-1.282.282", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "downstream", "id": "O88310-1.284.284", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "downstream", "id": "O88310-1.285.285", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "downstream", "id": "O88310-1.288.288", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "downstream", "id": "O88310-1.289.289", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "downstream", "id": "O88310-1.295.295", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "downstream", "id": "O88310-1.296.296", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "downstream", "id": "O88310-1.297.297", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "downstream", "id": "O88310-1.299.299", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "upstream", "id": "O88310-1.302.302", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "upstream", "id": "O88310-1.305.305", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "upstream", "id": "O88310-1.307.307", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "upstream", "id": "O88310-1.313.313", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.302.302", "start_pos": 302, "end_pos": 302, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs584496238", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs584496238", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "DFASFDWDGYGTHNGYSSSR", "down_seq": "ITEAAVLLFYR", "snv": [ { "evidence": [ { "id": "rs584496238", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs584496238" } ], "glycoeffect": [], "sequence_org": "K", "sequence_mut": "E", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171345847", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "K302", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "O88310-1.282.282", "categories": [ "snv_flag" ] }, { "distance": 18, "direction": "downstream", "id": "O88310-1.284.284", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "downstream", "id": "O88310-1.285.285", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "downstream", "id": "O88310-1.288.288", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "downstream", "id": "O88310-1.289.289", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "downstream", "id": "O88310-1.295.295", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "downstream", "id": "O88310-1.296.296", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "downstream", "id": "O88310-1.297.297", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "downstream", "id": "O88310-1.299.299", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "downstream", "id": "O88310-1.301.301", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "upstream", "id": "O88310-1.305.305", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "upstream", "id": "O88310-1.307.307", "categories": [ "snv_flag" ] }, { "distance": 11, "direction": "upstream", "id": "O88310-1.313.313", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.305.305", "start_pos": 305, "end_pos": 305, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388516682", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388516682", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "E", "start_aa": "E", "up_seq": "SFDWDGYGTHNGYSSSRKIT", "down_seq": "AAVLLFYR", "snv": [ { "evidence": [ { "id": "rs3388516682", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388516682" } ], "glycoeffect": [], "sequence_org": "E", "sequence_mut": "K", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171345838", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "E305", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "O88310-1.285.285", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "downstream", "id": "O88310-1.288.288", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "downstream", "id": "O88310-1.289.289", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "downstream", "id": "O88310-1.295.295", "categories": [ "snv_flag" ] }, { "distance": 9, "direction": "downstream", "id": "O88310-1.296.296", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "downstream", "id": "O88310-1.297.297", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "downstream", "id": "O88310-1.299.299", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "downstream", "id": "O88310-1.301.301", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "downstream", "id": "O88310-1.302.302", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "upstream", "id": "O88310-1.307.307", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "upstream", "id": "O88310-1.313.313", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.307.307", "start_pos": 307, "end_pos": 307, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3539924035", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3539924035", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "A", "start_aa": "A", "up_seq": "DWDGYGTHNGYSSSRKITEA", "down_seq": "VLLFYR", "snv": [ { "evidence": [ { "id": "rs3539924035", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3539924035" } ], "glycoeffect": [], "sequence_org": "A", "sequence_mut": "T", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171345832", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "A307", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "O88310-1.288.288", "categories": [ "snv_flag" ] }, { "distance": 18, "direction": "downstream", "id": "O88310-1.289.289", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "downstream", "id": "O88310-1.295.295", "categories": [ "snv_flag" ] }, { "distance": 11, "direction": "downstream", "id": "O88310-1.296.296", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "downstream", "id": "O88310-1.297.297", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "downstream", "id": "O88310-1.299.299", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "downstream", "id": "O88310-1.301.301", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "downstream", "id": "O88310-1.302.302", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "downstream", "id": "O88310-1.305.305", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "upstream", "id": "O88310-1.313.313", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.30.30", "start_pos": 30, "end_pos": 30, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3539925157", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3539925157", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "G", "start_aa": "G", "up_seq": "IMVATRGCSAAEENLDTNRW", "down_seq": "NSFFSSLPRSCKEIKQEHTK", "snv": [ { "evidence": [ { "id": "rs3539925157", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3539925157" } ], "glycoeffect": [], "sequence_org": "G", "sequence_mut": "V", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171361002", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "G30", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "O88310-1.12.12", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "downstream", "id": "O88310-1.14.14", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "downstream", "id": "O88310-1.16.16", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "downstream", "id": "O88310-1.17.17", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "downstream", "id": "O88310-1.22.22", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "downstream", "id": "O88310-1.23.23", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "downstream", "id": "O88310-1.25.25", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "upstream", "id": "O88310-1.31.31", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "upstream", "id": "O88310-1.32.32", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "upstream", "id": "O88310-1.35.35", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "upstream", "id": "O88310-1.36.36", "categories": [ "snv_flag" ] }, { "distance": 9, "direction": "upstream", "id": "O88310-1.39.39", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "upstream", "id": "O88310-1.47.47", "categories": [ "snv_flag" ] }, { "distance": 18, "direction": "upstream", "id": "O88310-1.48.48", "categories": [ "snv_flag" ] }, { "distance": 19, "direction": "upstream", "id": "O88310-1.49.49", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.313.313", "start_pos": 313, "end_pos": 313, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3539923112", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3539923112", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "THNGYSSSRKITEAAVLLFY", "down_seq": "", "snv": [ { "evidence": [ { "id": "rs3539923112", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3539923112" } ], "glycoeffect": [], "sequence_org": "R", "sequence_mut": "H", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171345813", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "R313", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "O88310-1.295.295", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "downstream", "id": "O88310-1.296.296", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "downstream", "id": "O88310-1.297.297", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "downstream", "id": "O88310-1.299.299", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "downstream", "id": "O88310-1.301.301", "categories": [ "snv_flag" ] }, { "distance": 11, "direction": "downstream", "id": "O88310-1.302.302", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "downstream", "id": "O88310-1.305.305", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "downstream", "id": "O88310-1.307.307", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.31.31", "start_pos": 31, "end_pos": 31, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs1133148672", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1133148672", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "MVATRGCSAAEENLDTNRWG", "down_seq": "SFFSSLPRSCKEIKQEHTKA", "snv": [ { "evidence": [ { "id": "rs1133148672", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1133148672" } ], "glycoeffect": [], "sequence_org": "N", "sequence_mut": "K", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171360998", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "N31", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "O88310-1.12.12", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "downstream", "id": "O88310-1.14.14", "categories": [ "snv_flag" ] }, { "distance": 15, "direction": "downstream", "id": "O88310-1.16.16", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "downstream", "id": "O88310-1.17.17", "categories": [ "snv_flag" ] }, { "distance": 9, "direction": "downstream", "id": "O88310-1.22.22", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "downstream", "id": "O88310-1.23.23", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "downstream", "id": "O88310-1.25.25", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "downstream", "id": "O88310-1.30.30", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "upstream", "id": "O88310-1.32.32", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "upstream", "id": "O88310-1.35.35", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "upstream", "id": "O88310-1.36.36", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "upstream", "id": "O88310-1.39.39", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "upstream", "id": "O88310-1.47.47", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "upstream", "id": "O88310-1.48.48", "categories": [ "snv_flag" ] }, { "distance": 18, "direction": "upstream", "id": "O88310-1.49.49", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.32.32", "start_pos": 32, "end_pos": 32, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs1132043905", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1132043905", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VATRGCSAAEENLDTNRWGN", "down_seq": "FFSSLPRSCKEIKQEHTKAQ", "snv": [ { "evidence": [ { "id": "rs1132043905", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1132043905" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "S", "sequence_mut": "Y", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171360996", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S32", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "O88310-1.12.12", "categories": [ "snv_flag" ] }, { "distance": 18, "direction": "downstream", "id": "O88310-1.14.14", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "downstream", "id": "O88310-1.16.16", "categories": [ "snv_flag" ] }, { "distance": 15, "direction": "downstream", "id": "O88310-1.17.17", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "downstream", "id": "O88310-1.22.22", "categories": [ "snv_flag" ] }, { "distance": 9, "direction": "downstream", "id": "O88310-1.23.23", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "downstream", "id": "O88310-1.25.25", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "downstream", "id": "O88310-1.30.30", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "downstream", "id": "O88310-1.31.31", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "upstream", "id": "O88310-1.35.35", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "upstream", "id": "O88310-1.36.36", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "upstream", "id": "O88310-1.39.39", "categories": [ "snv_flag" ] }, { "distance": 15, "direction": "upstream", "id": "O88310-1.47.47", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "upstream", "id": "O88310-1.48.48", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "upstream", "id": "O88310-1.49.49", "categories": [ "snv_flag" ] }, { "distance": 20, "direction": "upstream", "id": "O88310-1.52.52", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.35.35", "start_pos": 35, "end_pos": 35, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3390999462", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3390999462", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RGCSAAEENLDTNRWGNSFF", "down_seq": "SLPRSCKEIKQEHTKAQDGL", "snv": [ { "evidence": [ { "id": "rs3390999462", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3390999462" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "S", "sequence_mut": "F", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171360987", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S35", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "O88310-1.16.16", "categories": [ "snv_flag" ] }, { "distance": 18, "direction": "downstream", "id": "O88310-1.17.17", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "downstream", "id": "O88310-1.22.22", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "downstream", "id": "O88310-1.23.23", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "downstream", "id": "O88310-1.25.25", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "downstream", "id": "O88310-1.30.30", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "downstream", "id": "O88310-1.31.31", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "downstream", "id": "O88310-1.32.32", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "upstream", "id": "O88310-1.36.36", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "upstream", "id": "O88310-1.39.39", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "upstream", "id": "O88310-1.47.47", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "upstream", "id": "O88310-1.48.48", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "upstream", "id": "O88310-1.49.49", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "upstream", "id": "O88310-1.52.52", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.36.36", "start_pos": 36, "end_pos": 36, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388516998", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388516998", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GCSAAEENLDTNRWGNSFFS", "down_seq": "LPRSCKEIKQEHTKAQDGLY", "snv": [ { "evidence": [ { "id": "rs3388516998", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388516998" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "S", "sequence_mut": "P", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171360985", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S36", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "O88310-1.16.16", "categories": [ "snv_flag" ] }, { "distance": 19, "direction": "downstream", "id": "O88310-1.17.17", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "downstream", "id": "O88310-1.22.22", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "downstream", "id": "O88310-1.23.23", "categories": [ "snv_flag" ] }, { "distance": 11, "direction": "downstream", "id": "O88310-1.25.25", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "downstream", "id": "O88310-1.30.30", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "downstream", "id": "O88310-1.31.31", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "downstream", "id": "O88310-1.32.32", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "downstream", "id": "O88310-1.35.35", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "upstream", "id": "O88310-1.39.39", "categories": [ "snv_flag" ] }, { "distance": 11, "direction": "upstream", "id": "O88310-1.47.47", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "upstream", "id": "O88310-1.48.48", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "upstream", "id": "O88310-1.49.49", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "upstream", "id": "O88310-1.52.52", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.39.39", "start_pos": 39, "end_pos": 39, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs1135225124", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1135225124", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "AAEENLDTNRWGNSFFSSLP", "down_seq": "SCKEIKQEHTKAQDGLYFLR", "snv": [ { "evidence": [ { "id": "rs1135225124", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1135225124" } ], "glycoeffect": [], "sequence_org": "R", "sequence_mut": "K", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171360975", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "R39", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "O88310-1.22.22", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "downstream", "id": "O88310-1.23.23", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "downstream", "id": "O88310-1.25.25", "categories": [ "snv_flag" ] }, { "distance": 9, "direction": "downstream", "id": "O88310-1.30.30", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "downstream", "id": "O88310-1.31.31", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "downstream", "id": "O88310-1.32.32", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "downstream", "id": "O88310-1.35.35", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "downstream", "id": "O88310-1.36.36", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "upstream", "id": "O88310-1.47.47", "categories": [ "snv_flag" ] }, { "distance": 9, "direction": "upstream", "id": "O88310-1.48.48", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "upstream", "id": "O88310-1.49.49", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "upstream", "id": "O88310-1.52.52", "categories": [ "snv_flag" ] }, { "distance": 20, "direction": "upstream", "id": "O88310-1.59.59", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.47.47", "start_pos": 47, "end_pos": 47, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3539934541", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3539934541", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "E", "start_aa": "E", "up_seq": "NRWGNSFFSSLPRSCKEIKQ", "down_seq": "HTKAQDGLYFLRTKNGVIYQ", "snv": [ { "evidence": [ { "id": "rs3539934541", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3539934541" } ], "glycoeffect": [], "sequence_org": "E", "sequence_mut": "V", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171360951", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "E47", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "O88310-1.30.30", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "downstream", "id": "O88310-1.31.31", "categories": [ "snv_flag" ] }, { "distance": 15, "direction": "downstream", "id": "O88310-1.32.32", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "downstream", "id": "O88310-1.35.35", "categories": [ "snv_flag" ] }, { "distance": 11, "direction": "downstream", "id": "O88310-1.36.36", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "downstream", "id": "O88310-1.39.39", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "upstream", "id": "O88310-1.48.48", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "upstream", "id": "O88310-1.49.49", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "upstream", "id": "O88310-1.52.52", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "upstream", "id": "O88310-1.59.59", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "upstream", "id": "O88310-1.60.60", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "upstream", "id": "O88310-1.61.61", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.48.48", "start_pos": 48, "end_pos": 48, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs217580490", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs217580490", "database": "dbSNP", "categories": [ "Other" ] }, { "id": "rs1134816041", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1134816041", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "H", "start_aa": "H", "up_seq": "RWGNSFFSSLPRSCKEIKQE", "down_seq": "TKAQDGLYFLRTKNGVIYQT", "snv": [ { "evidence": [ { "id": "rs217580490", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs217580490" } ], "glycoeffect": [], "sequence_org": "H", "sequence_mut": "D", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171360949", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "H48", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs1134816041", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1134816041" } ], "glycoeffect": [], "sequence_org": "H", "sequence_mut": "L", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171360948", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "H48", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "O88310-1.30.30", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "downstream", "id": "O88310-1.31.31", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "downstream", "id": "O88310-1.32.32", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "downstream", "id": "O88310-1.35.35", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "downstream", "id": "O88310-1.36.36", "categories": [ "snv_flag" ] }, { "distance": 9, "direction": "downstream", "id": "O88310-1.39.39", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "downstream", "id": "O88310-1.47.47", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "upstream", "id": "O88310-1.49.49", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "upstream", "id": "O88310-1.52.52", "categories": [ "snv_flag" ] }, { "distance": 11, "direction": "upstream", "id": "O88310-1.59.59", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "upstream", "id": "O88310-1.60.60", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "upstream", "id": "O88310-1.61.61", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.49.49", "start_pos": 49, "end_pos": 49, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs1134622924", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1134622924", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "WGNSFFSSLPRSCKEIKQEH", "down_seq": "KAQDGLYFLRTKNGVIYQTF", "snv": [ { "evidence": [ { "id": "rs1134622924", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1134622924" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "T", "sequence_mut": "R", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171360945", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "T49", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "O88310-1.30.30", "categories": [ "snv_flag" ] }, { "distance": 18, "direction": "downstream", "id": "O88310-1.31.31", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "downstream", "id": "O88310-1.32.32", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "downstream", "id": "O88310-1.35.35", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "downstream", "id": "O88310-1.36.36", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "downstream", "id": "O88310-1.39.39", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "downstream", "id": "O88310-1.47.47", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "downstream", "id": "O88310-1.48.48", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "upstream", "id": "O88310-1.52.52", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "upstream", "id": "O88310-1.59.59", "categories": [ "snv_flag" ] }, { "distance": 11, "direction": "upstream", "id": "O88310-1.60.60", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "upstream", "id": "O88310-1.61.61", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.52.52", "start_pos": 52, "end_pos": 52, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3539929348", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3539929348", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "Q", "start_aa": "Q", "up_seq": "SFFSSLPRSCKEIKQEHTKA", "down_seq": "DGLYFLRTKNGVIYQTFCDM", "snv": [ { "evidence": [ { "id": "rs3539929348", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3539929348" } ], "glycoeffect": [], "sequence_org": "Q", "sequence_mut": "R", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171360936", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "Q52", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "O88310-1.32.32", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "downstream", "id": "O88310-1.35.35", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "downstream", "id": "O88310-1.36.36", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "downstream", "id": "O88310-1.39.39", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "downstream", "id": "O88310-1.47.47", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "downstream", "id": "O88310-1.48.48", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "downstream", "id": "O88310-1.49.49", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "upstream", "id": "O88310-1.59.59", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "upstream", "id": "O88310-1.60.60", "categories": [ "snv_flag" ] }, { "distance": 9, "direction": "upstream", "id": "O88310-1.61.61", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.59.59", "start_pos": 59, "end_pos": 59, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs1133979992", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1133979992", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "RSCKEIKQEHTKAQDGLYFL", "down_seq": "TKNGVIYQTFCDMTTAGGGW", "snv": [ { "evidence": [ { "id": "rs1133979992", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1133979992" } ], "glycoeffect": [], "sequence_org": "R", "sequence_mut": "H", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171359303", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "R59", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "O88310-1.39.39", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "downstream", "id": "O88310-1.47.47", "categories": [ "snv_flag" ] }, { "distance": 11, "direction": "downstream", "id": "O88310-1.48.48", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "downstream", "id": "O88310-1.49.49", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "downstream", "id": "O88310-1.52.52", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "upstream", "id": "O88310-1.60.60", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "upstream", "id": "O88310-1.61.61", "categories": [ "snv_flag" ] }, { "distance": 15, "direction": "upstream", "id": "O88310-1.74.74", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.5.5", "start_pos": 5, "end_pos": 5, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3539924602", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3539924602", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "G", "start_aa": "G", "up_seq": "MTQL", "down_seq": "FLLFIMVATRGCSAAEENLD", "snv": [ { "evidence": [ { "id": "rs3539924602", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3539924602" } ], "glycoeffect": [], "sequence_org": "G", "sequence_mut": "R", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171362367", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "G5", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "upstream", "id": "O88310-1.12.12", "categories": [ "snv_flag" ] }, { "distance": 9, "direction": "upstream", "id": "O88310-1.14.14", "categories": [ "snv_flag" ] }, { "distance": 11, "direction": "upstream", "id": "O88310-1.16.16", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "upstream", "id": "O88310-1.17.17", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "upstream", "id": "O88310-1.22.22", "categories": [ "snv_flag" ] }, { "distance": 18, "direction": "upstream", "id": "O88310-1.23.23", "categories": [ "snv_flag" ] }, { "distance": 20, "direction": "upstream", "id": "O88310-1.25.25", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.60.60", "start_pos": 60, "end_pos": 60, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs1133829892", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1133829892", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "SCKEIKQEHTKAQDGLYFLR", "down_seq": "KNGVIYQTFCDMTTAGGGWT", "snv": [ { "evidence": [ { "id": "rs1133829892", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1133829892" } ], "glycoeffect": [], "sequence_org": "T", "sequence_mut": "S", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171359301", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "T60", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "O88310-1.47.47", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "downstream", "id": "O88310-1.48.48", "categories": [ "snv_flag" ] }, { "distance": 11, "direction": "downstream", "id": "O88310-1.49.49", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "downstream", "id": "O88310-1.52.52", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "downstream", "id": "O88310-1.59.59", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "upstream", "id": "O88310-1.61.61", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "upstream", "id": "O88310-1.74.74", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.61.61", "start_pos": 61, "end_pos": 61, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs47001749", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs47001749", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "CKEIKQEHTKAQDGLYFLRT", "down_seq": "NGVIYQTFCDMTTAGGGWTL", "snv": [ { "evidence": [ { "id": "rs47001749", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs47001749" } ], "glycoeffect": [], "sequence_org": "K", "sequence_mut": "E", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171359298", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "K61", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "O88310-1.47.47", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "downstream", "id": "O88310-1.48.48", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "downstream", "id": "O88310-1.49.49", "categories": [ "snv_flag" ] }, { "distance": 9, "direction": "downstream", "id": "O88310-1.52.52", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "downstream", "id": "O88310-1.59.59", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "downstream", "id": "O88310-1.60.60", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "upstream", "id": "O88310-1.74.74", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.74.74", "start_pos": 74, "end_pos": 74, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3539930015", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3539930015", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "GLYFLRTKNGVIYQTFCDMT", "down_seq": "AGGGWTLVASVHENNMRGKC", "snv": [ { "evidence": [ { "id": "rs3539930015", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3539930015" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "T", "sequence_mut": "I", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171359258", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "T74", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "O88310-1.59.59", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "downstream", "id": "O88310-1.60.60", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "downstream", "id": "O88310-1.61.61", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "upstream", "id": "O88310-1.90.90", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "upstream", "id": "O88310-1.91.91", "categories": [ "snv_flag" ] }, { "distance": 19, "direction": "upstream", "id": "O88310-1.93.93", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.90.90", "start_pos": 90, "end_pos": 90, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs46137372", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs46137372", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "M", "start_aa": "M", "up_seq": "CDMTTAGGGWTLVASVHENN", "down_seq": "RGKCTVGDRWSSQQGNRADY", "snv": [ { "evidence": [ { "id": "rs46137372", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs46137372" } ], "glycoeffect": [], "sequence_org": "M", "sequence_mut": "L", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171359211", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "M90", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "O88310-1.74.74", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "upstream", "id": "O88310-1.91.91", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "upstream", "id": "O88310-1.93.93", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.91.91", "start_pos": 91, "end_pos": 91, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs1134891862", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1134891862", "database": "dbSNP", "categories": [ "Other" ] }, { "id": "rs1134357990", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1134357990", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "DMTTAGGGWTLVASVHENNM", "down_seq": "GKCTVGDRWSSQQGNRADYP", "snv": [ { "evidence": [ { "id": "rs1134891862", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1134891862" } ], "glycoeffect": [], "sequence_org": "R", "sequence_mut": "G", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171359208", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "R91", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs1134357990", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1134357990" } ], "glycoeffect": [], "sequence_org": "R", "sequence_mut": "H", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171359207", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "R91", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "O88310-1.74.74", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "downstream", "id": "O88310-1.90.90", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "upstream", "id": "O88310-1.93.93", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88310-1.93.93", "start_pos": 93, "end_pos": 93, "uniprot_canonical_ac": "O88310-1", "length": 313, "uniprot_id": "ITL1A_MOUSE", "protein_name": "Intelectin-1a", "refseq_ac": "NP_034714", "refseq_name": "intelectin-1a precursor", "gene_name": "Itln1", "gene_names_uniprotkb": "Itln1; Intl; Itln1a; Itlna; Itln", "gene_names_refseq": "IntL; Itln1; Itln2; Itln3; Itln5; Itlna; Itln; Lfr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88310", "url": "https://www.uniprot.org/uniprotkb/O88310" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs48219866", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs48219866", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "TTAGGGWTLVASVHENNMRG", "down_seq": "CTVGDRWSSQQGNRADYPEG", "snv": [ { "evidence": [ { "id": "rs48219866", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs48219866" } ], "glycoeffect": [], "sequence_org": "K", "sequence_mut": "R", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene,.", "chr_id": "1", "chr_pos": "171359201", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "K93", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "143", "end_pos": "143" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "155", "end_pos": "155" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "190", "end_pos": "190" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "25", "end_pos": "25" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "49", "end_pos": "49" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "90", "end_pos": "90" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "93", "end_pos": "93" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "O88310-1.74.74", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "downstream", "id": "O88310-1.90.90", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "downstream", "id": "O88310-1.91.91", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P81067-1.326.326", "start_pos": 326, "end_pos": 326, "uniprot_canonical_ac": "P81067-1", "length": 507, "uniprot_id": "IRX3_MOUSE", "protein_name": "Iroquois-class homeodomain protein IRX-3", "refseq_ac": "NP_001240751", "refseq_name": "iroquois-class homeodomain protein IRX-3 isoform 1", "gene_name": "Irx3", "gene_names_uniprotkb": "Irx3; Irxb1", "gene_names_refseq": "Irx3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81067", "url": "https://www.uniprot.org/uniprotkb/P81067" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P81067", "url": "https://www.uniprot.org/uniprotkb/P81067" }, { "database": "iPTMnet", "id": "P81067", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P81067" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "P81067", "url": "https://www.uniprot.org/uniprotkb/P81067", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P81067", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P81067", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RPLSVLSLAPPPPPVARAPA", "down_seq": "PPSPPSSLDPCAPAPAPSSA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P81067", "url": "https://www.uniprot.org/uniprotkb/P81067" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "P81067", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P81067" } ], "site_lbl": "Ser326" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "326", "end_pos": "326" }, { "start_pos": "329", "end_pos": "329" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "P81067-1.329.329", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P81067-1.329.329", "start_pos": 329, "end_pos": 329, "uniprot_canonical_ac": "P81067-1", "length": 507, "uniprot_id": "IRX3_MOUSE", "protein_name": "Iroquois-class homeodomain protein IRX-3", "refseq_ac": "NP_001240751", "refseq_name": "iroquois-class homeodomain protein IRX-3 isoform 1", "gene_name": "Irx3", "gene_names_uniprotkb": "Irx3; Irxb1", "gene_names_refseq": "Irx3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81067", "url": "https://www.uniprot.org/uniprotkb/P81067" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P81067", "url": "https://www.uniprot.org/uniprotkb/P81067" }, { "database": "iPTMnet", "id": "P81067", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P81067" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "P81067", "url": "https://www.uniprot.org/uniprotkb/P81067", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P81067", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P81067", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SVLSLAPPPPPVARAPASPP", "down_seq": "PPSSLDPCAPAPAPSSALQK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P81067", "url": "https://www.uniprot.org/uniprotkb/P81067" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "P81067", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P81067" } ], "site_lbl": "Ser329" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "326", "end_pos": "326" }, { "start_pos": "329", "end_pos": "329" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "P81067-1.326.326", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P81122-1.1046.1046", "start_pos": 1046, "end_pos": 1046, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "PAPGDLYRLPPASAATSQGP", "down_seq": "AGSSMSSEPGDNGDYTEMAF", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1046", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P81122-1.1091.1091", "start_pos": 1091, "end_pos": 1091, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "TPPQPIVAPPKPEGARVASP", "down_seq": "SGLKRLSLMDQVSGVEAFLQ", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1091", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P81122-1.1071.1071", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P81122-1.1089.1089", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P81122-1.1098.1098", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P81122-1.1144.1144", "start_pos": 1144, "end_pos": 1144, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "P81122", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P81122" }, { "database": "O-GlcNAc Atlas", "id": "P81122", "url": "https://oglcnac.org/atlas/detail/P81122" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Characterization and chemoproteomic profiling of protein O-GlcNAcylation in SOD1-G93A mouse model.", "journal": "Molecular medicine (Cambridge, Mass.)", "date": "2025-02-28", "authors": "Hao Yi, Li Zhongzhong, Du Xinyan, Xie Qingsong, Li Dongxiao, Lei Shaoyuan, Guo Yansu", "evidence": [ { "database": "O-GlcNAc Database", "id": "P81122", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P81122" } ], "reference": [ { "type": "PubMed", "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "P81122", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P81122" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Cytosolic N-GlcNAc proteins are formed by the action of endo-beta-N-acetylglucosaminidase.", "journal": "Biochemical and biophysical research communications", "date": "2020", "authors": "Maynard JC, Fujihira H, Dolgonos GE, Suzuki T, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "P81122", "url": "https://oglcnac.org/atlas/detail/P81122" } ], "reference": [ { "type": "PubMed", "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141" } ] } ], "crossref": [ { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P81122", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P81122", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P81122", "url": "https://oglcnac.org/atlas/detail/P81122", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "VIRADPQGGRRRHSSETFSS", "down_seq": "TTVTPVSPSFAHNSKRHNSA", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1144", "evidence": [ { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "P81122", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P81122" }, { "id": "40021952", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40021952" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "P81122", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P81122" }, { "id": "32782141", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32782141" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "P81122-1.1145.1145", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P81122-1.1148.1148", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P81122-1.1151.1151", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P81122-1.1163.1163", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P81122-1.1145.1145", "start_pos": 1145, "end_pos": 1145, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Cytosolic N-GlcNAc proteins are formed by the action of endo-beta-N-acetylglucosaminidase.", "journal": "Biochemical and biophysical research communications", "date": "2020", "authors": "Maynard JC, Fujihira H, Dolgonos GE, Suzuki T, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "P81122", "url": "https://oglcnac.org/atlas/detail/P81122" } ], "reference": [ { "type": "PubMed", "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141" } ] } ], "crossref": [ { "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P81122", "url": "https://oglcnac.org/atlas/detail/P81122", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "IRADPQGGRRRHSSETFSST", "down_seq": "TVTPVSPSFAHNSKRHNSAS", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1145", "evidence": [ { "id": "32782141", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32782141" }, { "id": "P81122", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P81122" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "P81122-1.1144.1144", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P81122-1.1148.1148", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P81122-1.1151.1151", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P81122-1.1163.1163", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P81122-1.1165.1165", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P81122-1.185.185", "start_pos": 185, "end_pos": 185, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "PGVLGGSAGAAGCDDNYGLV", "down_seq": "PATAVYREVWQVNLKPKGLG", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr185", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P81122-1.209.209", "start_pos": 209, "end_pos": 209, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "AVYREVWQVNLKPKGLGQSK", "down_seq": "LTGVYRLCLSARTIGFVKLN", "glycosylation": [ { "glytoucan_ac": "G34071NT", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "GLGQSKNLTGVYR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn209", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P81122-1.303.303", "start_pos": 303, "end_pos": 303, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "P81122", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P81122" }, { "database": "O-GlcNAc Atlas", "id": "P81122", "url": "https://oglcnac.org/atlas/detail/P81122" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] } ], "crossref": [ { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P81122", "url": "https://oglcnac.org/atlas/detail/P81122", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TILEAMKALKELFEFRPRSK", "down_seq": "QSSGSSATHPISVPGARRHH", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser303", "evidence": [ { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "P81122", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P81122" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "site_lbl": "Ser303" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P81122-1.414.414", "start_pos": 414, "end_pos": 414, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "P81122", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P81122" }, { "database": "O-GlcNAc Atlas", "id": "P81122", "url": "https://oglcnac.org/atlas/detail/P81122" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Characterization and chemoproteomic profiling of protein O-GlcNAcylation in SOD1-G93A mouse model.", "journal": "Molecular medicine (Cambridge, Mass.)", "date": "2025-02-28", "authors": "Hao Yi, Li Zhongzhong, Du Xinyan, Xie Qingsong, Li Dongxiao, Lei Shaoyuan, Guo Yansu", "evidence": [ { "database": "O-GlcNAc Database", "id": "P81122", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P81122" } ], "reference": [ { "type": "PubMed", "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "P81122", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P81122" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] } ], "crossref": [ { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P81122", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P81122", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "APLSRSHTLSAGCGGRPSKV", "down_seq": "LAPAGGALQHSRSMSMPVAH", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr414", "evidence": [ { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "P81122", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P81122" }, { "id": "40021952", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40021952" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "upstream", "id": "P81122-1.425.425", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P81122-1.425.425", "start_pos": 425, "end_pos": 425, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "P81122", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P81122" }, { "database": "O-GlcNAc Atlas", "id": "P81122", "url": "https://oglcnac.org/atlas/detail/P81122" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Cytosolic N-GlcNAc proteins are formed by the action of endo-beta-N-acetylglucosaminidase.", "journal": "Biochemical and biophysical research communications", "date": "2020", "authors": "Maynard JC, Fujihira H, Dolgonos GE, Suzuki T, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "P81122", "url": "https://oglcnac.org/atlas/detail/P81122" } ], "reference": [ { "type": "PubMed", "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141" } ] } ], "crossref": [ { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P81122", "url": "https://oglcnac.org/atlas/detail/P81122", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GCGGRPSKVTLAPAGGALQH", "down_seq": "RSMSMPVAHSPPAATSPGSL", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser425", "evidence": [ { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "P81122", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P81122" }, { "id": "32782141", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32782141" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "P81122-1.414.414", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P81122-1.806.806", "start_pos": 806, "end_pos": 806, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Cytosolic N-GlcNAc proteins are formed by the action of endo-beta-N-acetylglucosaminidase.", "journal": "Biochemical and biophysical research communications", "date": "2020", "authors": "Maynard JC, Fujihira H, Dolgonos GE, Suzuki T, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "P81122", "url": "https://oglcnac.org/atlas/detail/P81122" } ], "reference": [ { "type": "PubMed", "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141" } ] } ], "crossref": [ { "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P81122", "url": "https://oglcnac.org/atlas/detail/P81122", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LKGIPGHCYSSLPRSYKAPC", "down_seq": "CSGDNDQYVLMSSPVGRILE", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser806", "evidence": [ { "id": "32782141", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32782141" }, { "id": "P81122", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P81122" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "P81122-1.796.796", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P81122-1.819.819", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P81122-1.835.835", "start_pos": 835, "end_pos": 835, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "VLMSSPVGRILEEERLEPQA", "down_seq": "PGAGTFGAAGGSHTQPHHSA", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr835", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P81122-1.819.819", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P81122-1.1071.1071", "start_pos": 1071, "end_pos": 1071, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "MSSEPGDNGDYTEMAFGVAA", "down_seq": "PPQPIVAPPKPEGARVASPT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "site_lbl": "Thr1071" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "upstream", "id": "P81122-1.1089.1089", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P81122-1.1091.1091", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P81122-1.1089.1089", "start_pos": 1089, "end_pos": 1089, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AATPPQPIVAPPKPEGARVA", "down_seq": "PTSGLKRLSLMDQVSGVEAF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "site_lbl": "Ser1089" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P81122-1.1071.1071", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P81122-1.1091.1091", "categories": [ "glycosylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P81122-1.1098.1098", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P81122-1.1098.1098", "start_pos": 1098, "end_pos": 1098, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "APPKPEGARVASPTSGLKRL", "down_seq": "LMDQVSGVEAFLQVSQPPDP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by PLK1", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "site_lbl": "Ser1098" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "P81122-1.1089.1089", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P81122-1.1091.1091", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P81122-1.1148.1148", "start_pos": 1148, "end_pos": 1148, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "DPQGGRRRHSSETFSSTTTV", "down_seq": "PVSPSFAHNSKRHNSASVEN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "site_lbl": "Thr1148" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "P81122-1.1144.1144", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P81122-1.1145.1145", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P81122-1.1151.1151", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P81122-1.1163.1163", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P81122-1.1165.1165", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P81122-1.1151.1151", "start_pos": 1151, "end_pos": 1151, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" }, { "database": "iPTMnet", "id": "P81122", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P81122" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P81122", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P81122", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GGRRRHSSETFSSTTTVTPV", "down_seq": "PSFAHNSKRHNSASVENVSL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "P81122", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P81122" } ], "site_lbl": "Ser1151" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "P81122-1.1144.1144", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P81122-1.1145.1145", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P81122-1.1148.1148", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P81122-1.1163.1163", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P81122-1.1165.1165", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P81122-1.1163.1163", "start_pos": 1163, "end_pos": 1163, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "STTTVTPVSPSFAHNSKRHN", "down_seq": "ASVENVSLRKSSEGSSTLGG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "site_lbl": "Ser1163" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P81122-1.1144.1144", "categories": [ "glycosylation_flag" ] }, { "distance": 18, "direction": "downstream", "id": "P81122-1.1145.1145", "categories": [ "glycosylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P81122-1.1148.1148", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P81122-1.1151.1151", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P81122-1.1165.1165", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P81122-1.1175.1175", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P81122-1.1165.1165", "start_pos": 1165, "end_pos": 1165, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" }, { "database": "iPTMnet", "id": "P81122", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P81122" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P81122", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P81122", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TTVTPVSPSFAHNSKRHNSA", "down_seq": "VENVSLRKSSEGSSTLGGGD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "P81122", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P81122" } ], "site_lbl": "Ser1165" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P81122-1.1145.1145", "categories": [ "glycosylation_flag" ] }, { "distance": 17, "direction": "downstream", "id": "P81122-1.1148.1148", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P81122-1.1151.1151", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P81122-1.1163.1163", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P81122-1.1175.1175", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P81122-1.1175.1175", "start_pos": 1175, "end_pos": 1175, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AHNSKRHNSASVENVSLRKS", "down_seq": "EGSSTLGGGDEPPTSPGQAQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "site_lbl": "Ser1175" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "P81122-1.1163.1163", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P81122-1.1165.1165", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P81122-1.1190.1190", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P81122-1.1190.1190", "start_pos": 1190, "end_pos": 1190, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SLRKSSEGSSTLGGGDEPPT", "down_seq": "PGQAQPLVAVPPVPQARPWN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "site_lbl": "Ser1190" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P81122-1.1175.1175", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P81122-1.1242.1242", "start_pos": 1242, "end_pos": 1242, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "GGSSSPMRRETSVGFQNGLN", "down_seq": "IAIDVRGEQGSLAQSQPQPG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by INSR", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "site_lbl": "Tyr1242" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P81122-1.1303.1303", "start_pos": 1303, "end_pos": 1303, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "SGASGVCGGPGTGALPSAST", "down_seq": "ASIDFLSHHLKEATVVKE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by INSR", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "site_lbl": "Tyr1303" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P81122-1.343.343", "start_pos": 343, "end_pos": 343, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "HHLVNLPPSQTGLVRRSRTD", "down_seq": "LAATPPAAKCTSCRVRTASE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "site_lbl": "Ser343" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "P81122-1.347.347", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P81122-1.362.362", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P81122-1.347.347", "start_pos": 347, "end_pos": 347, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "NLPPSQTGLVRRSRTDSLAA", "down_seq": "PPAAKCTSCRVRTASEGDGG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "site_lbl": "Thr347" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "P81122-1.343.343", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P81122-1.362.362", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P81122-1.362.362", "start_pos": 362, "end_pos": 362, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DSLAATPPAAKCTSCRVRTA", "down_seq": "EGDGGAAGGAGTAGGRPMSV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "site_lbl": "Ser362" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P81122-1.343.343", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P81122-1.347.347", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P81122-1.381.381", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P81122-1.381.381", "start_pos": 381, "end_pos": 381, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ASEGDGGAAGGAGTAGGRPM", "down_seq": "VAGSPLSPGPVRAPLSRSHT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "site_lbl": "Ser381" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P81122-1.362.362", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P81122-1.385.385", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P81122-1.388.388", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P81122-1.385.385", "start_pos": 385, "end_pos": 385, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" }, { "database": "iPTMnet", "id": "P81122", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P81122" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P81122", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P81122", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DGGAAGGAGTAGGRPMSVAG", "down_seq": "PLSPGPVRAPLSRSHTLSAG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "P81122", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P81122" } ], "site_lbl": "Ser385" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "P81122-1.381.381", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P81122-1.388.388", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P81122-1.388.388", "start_pos": 388, "end_pos": 388, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" }, { "database": "iPTMnet", "id": "P81122", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P81122" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "title": "CDK4 is an essential insulin effector in adipocytes.", "journal": "The Journal of clinical investigation", "date": "2016", "authors": "Lagarrigue S, Lopez-Mejia IC, Denechaud PD, Escote X, Castillo-Armengol J, Jimenez V, Chavey C, Giralt A, Lai Q, Zhang L, Martinez-Carreres L, Delacuisine B, Annicotte JS, Blanchet E, Hure S, Abella A, Tinahones FJ, Vendrell J, Dubus P, Bosch F, Kahn CR, Fajas L", "evidence": [ { "database": "iPTMnet", "id": "P81122", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P81122" } ], "reference": [ { "type": "PubMed", "id": "26657864", "url": "https://glygen.org/publication/PubMed/26657864" } ] } ], "crossref": [ { "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P81122", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P81122", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "26657864", "url": "https://glygen.org/publication/PubMed/26657864", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AAGGAGTAGGRPMSVAGSPL", "down_seq": "PGPVRAPLSRSHTLSAGCGG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "P81122", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P81122" }, { "database": "PubMed", "id": "26657864", "url": "https://glygen.org/publication/PubMed/26657864" } ], "site_lbl": "Ser388" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "P81122-1.381.381", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P81122-1.385.385", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P81122-1.500.500", "start_pos": 500, "end_pos": 500, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Targeted inactivation of the IL-4 receptor alpha chain I4R motif promotes allergic airway inflammation.", "journal": "The Journal of experimental medicine", "date": "2003", "authors": "Blaeser F, Bryce PJ, Ho N, Raman V, Dedeoglu F, Donaldson DD, Geha RS, Oettgen HC, Chatila TA", "evidence": [ { "database": "iPTMnet", "id": "P81122", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P81122" } ], "reference": [ { "type": "PubMed", "id": "14557412", "url": "https://glygen.org/publication/PubMed/14557412" } ] } ], "crossref": [ { "id": "P81122", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P81122", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "14557412", "url": "https://glygen.org/publication/PubMed/14557412", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "SGSASASGSPSDPGFMSLDE", "down_seq": "GSSPGDLRAFSSHRSNTPES", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P81122", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P81122" }, { "database": "PubMed", "id": "14557412", "url": "https://glygen.org/publication/PubMed/14557412" } ], "site_lbl": "Tyr500" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "upstream", "id": "P81122-1.517.517", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P81122-1.520.520", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P81122-1.517.517", "start_pos": 517, "end_pos": 517, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "LDEYGSSPGDLRAFSSHRSN", "down_seq": "PESIAETPPARDGSGGELYG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "site_lbl": "Thr517" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P81122-1.500.500", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P81122-1.520.520", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P81122-1.524.524", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P81122-1.536.536", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P81122-1.520.520", "start_pos": 520, "end_pos": 520, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "YGSSPGDLRAFSSHRSNTPE", "down_seq": "IAETPPARDGSGGELYGYMS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "site_lbl": "Ser520" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P81122-1.500.500", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P81122-1.517.517", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P81122-1.524.524", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P81122-1.536.536", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P81122-1.524.524", "start_pos": 524, "end_pos": 524, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" }, { "database": "iPTMnet", "id": "P81122", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P81122" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P81122", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P81122", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "PGDLRAFSSHRSNTPESIAE", "down_seq": "PPARDGSGGELYGYMSMDRP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "P81122", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P81122" } ], "site_lbl": "Thr524" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "P81122-1.517.517", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P81122-1.520.520", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P81122-1.536.536", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P81122-1.536.536", "start_pos": 536, "end_pos": 536, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "NTPESIAETPPARDGSGGEL", "down_seq": "GYMSMDRPLSHCGRPYRRVS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by INSR", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "site_lbl": "Tyr536" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P81122-1.517.517", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "P81122-1.520.520", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P81122-1.524.524", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P81122-1.556.556", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P81122-1.556.556", "start_pos": 556, "end_pos": 556, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "YGYMSMDRPLSHCGRPYRRV", "down_seq": "GDGAQDLDRGLRKRTYSLTT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by PLK1", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "site_lbl": "Ser556" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P81122-1.536.536", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P81122-1.573.573", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P81122-1.575.575", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P81122-1.576.576", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P81122-1.573.573", "start_pos": 573, "end_pos": 573, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RRVSGDGAQDLDRGLRKRTY", "down_seq": "LTTPARQRQVPQPSSASLDE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "site_lbl": "Ser573" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P81122-1.556.556", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P81122-1.575.575", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P81122-1.576.576", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P81122-1.590.590", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P81122-1.575.575", "start_pos": 575, "end_pos": 575, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "VSGDGAQDLDRGLRKRTYSL", "down_seq": "TPARQRQVPQPSSASLDEYT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "site_lbl": "Thr575" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P81122-1.556.556", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P81122-1.573.573", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P81122-1.576.576", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P81122-1.590.590", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P81122-1.576.576", "start_pos": 576, "end_pos": 576, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "SGDGAQDLDRGLRKRTYSLT", "down_seq": "PARQRQVPQPSSASLDEYTL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "site_lbl": "Thr576" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P81122-1.556.556", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P81122-1.573.573", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P81122-1.575.575", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P81122-1.590.590", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P81122-1.590.590", "start_pos": 590, "end_pos": 590, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RTYSLTTPARQRQVPQPSSA", "down_seq": "LDEYTLMRATFSGSSGRLCP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "site_lbl": "Ser590" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P81122-1.573.573", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P81122-1.575.575", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P81122-1.576.576", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P81122-1.604.604", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P81122-1.604.604", "start_pos": 604, "end_pos": 604, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PQPSSASLDEYTLMRATFSG", "down_seq": "SGRLCPSFPASSPKVAYNPY", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "site_lbl": "Ser604" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "P81122-1.590.590", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P81122-1.616.616", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P81122-1.616.616", "start_pos": 616, "end_pos": 616, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LMRATFSGSSGRLCPSFPAS", "down_seq": "PKVAYNPYPEDYGDIEIGSH", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "site_lbl": "Ser616" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "P81122-1.604.604", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P81122-1.649.649", "start_pos": 649, "end_pos": 649, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain.", "journal": "Journal of proteome research", "date": "2008", "authors": "Ballif BA, Carey GR, Sunyaev SR, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" }, { "database": "iPTMnet", "id": "P81122", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P81122" } ], "reference": [ { "type": "PubMed", "id": "18034455", "url": "https://glygen.org/publication/PubMed/18034455" } ] } ], "crossref": [ { "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18034455", "url": "https://glygen.org/publication/PubMed/18034455", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P81122", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P81122", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "GDIEIGSHKSSSSNLGADDG", "down_seq": "MPMTPGAALRSGGPNSCKSD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" }, { "database": "PubMed", "id": "18034455", "url": "https://glygen.org/publication/PubMed/18034455" }, { "database": "iPTMnet", "id": "P81122", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P81122" } ], "site_lbl": "Tyr649" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P81122-1.671.671", "start_pos": 671, "end_pos": 671, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "PMTPGAALRSGGPNSCKSDD", "down_seq": "MPMSPTSVSAPKQILQPRLA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by INSR", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "site_lbl": "Tyr671" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "P81122-1.675.675", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P81122-1.678.678", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P81122-1.675.675", "start_pos": 675, "end_pos": 675, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GAALRSGGPNSCKSDDYMPM", "down_seq": "PTSVSAPKQILQPRLAAALP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "site_lbl": "Ser675" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "P81122-1.671.671", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P81122-1.678.678", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P81122-1.678.678", "start_pos": 678, "end_pos": 678, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LRSGGPNSCKSDDYMPMSPT", "down_seq": "VSAPKQILQPRLAAALPPSG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "site_lbl": "Ser678" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "P81122-1.671.671", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P81122-1.675.675", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P81122-1.727.727", "start_pos": 727, "end_pos": 727, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GVGRTFPVNGGGYKASSPAE", "down_seq": "SPEDSGYMRMWCGSKLSMEN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "site_lbl": "Ser727" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "P81122-1.728.728", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P81122-1.728.728", "start_pos": 728, "end_pos": 728, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" }, { "database": "iPTMnet", "id": "P81122", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P81122" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P81122", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P81122", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VGRTFPVNGGGYKASSPAES", "down_seq": "PEDSGYMRMWCGSKLSMENP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "P81122", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P81122" } ], "site_lbl": "Ser728" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "P81122-1.727.727", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P81122-1.762.762", "start_pos": 762, "end_pos": 762, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KLSMENPDPKLLPNGDYLNM", "down_seq": "PSEAGTAGTPPDFSAALRGG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "site_lbl": "Ser762" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "upstream", "id": "P81122-1.771.771", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P81122-1.771.771", "start_pos": 771, "end_pos": 771, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "KLLPNGDYLNMSPSEAGTAG", "down_seq": "PPDFSAALRGGSEGLKGIPG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "site_lbl": "Thr771" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "P81122-1.762.762", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P81122-1.796.796", "start_pos": 796, "end_pos": 796, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SAALRGGSEGLKGIPGHCYS", "down_seq": "LPRSYKAPCSCSGDNDQYVL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "site_lbl": "Ser796" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "upstream", "id": "P81122-1.806.806", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P81122-1.819.819", "start_pos": 819, "end_pos": 819, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RSYKAPCSCSGDNDQYVLMS", "down_seq": "PVGRILEEERLEPQATPGAG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "site_lbl": "Ser819" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P81122-1.806.806", "categories": [ "glycosylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P81122-1.835.835", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P81122-1.907.907", "start_pos": 907, "end_pos": 907, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" }, { "database": "iPTMnet", "id": "P81122", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P81122" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P81122", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P81122", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LEGLQTLPSMQEYPLPTEPK", "down_seq": "PGEYINIDFGEAGTRLSPPA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "P81122", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P81122" } ], "site_lbl": "Ser907" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "P81122-1.911.911", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P81122-1.911.911", "start_pos": 911, "end_pos": 911, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "QTLPSMQEYPLPTEPKSPGE", "down_seq": "INIDFGEAGTRLSPPAPPLL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by INSR", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "site_lbl": "Tyr911" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "P81122-1.907.907", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P81122-1.965.965", "start_pos": 965, "end_pos": 965, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SPASSLGSGTPGTSSDSRQR", "down_seq": "PLSDYMNLDFSSPKSPKPST", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "site_lbl": "Ser965" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "upstream", "id": "P81122-1.970.970", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P81122-1.970.970", "start_pos": 970, "end_pos": 970, "uniprot_canonical_ac": "P81122-1", "length": 1321, "uniprot_id": "IRS2_MOUSE", "protein_name": "Insulin receptor substrate 2", "refseq_ac": "NP_001074681", "refseq_name": "insulin receptor substrate 2", "gene_name": "Irs2", "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs-2; Irs2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "LGSGTPGTSSDSRQRSPLSD", "down_seq": "MNLDFSSPKSPKPSTRSGDT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by INSR", "evidence": [ { "database": "UniProtKB", "id": "P81122", "url": "https://www.uniprot.org/uniprotkb/P81122" } ], "site_lbl": "Tyr970" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1046", "end_pos": "1046" }, { "start_pos": "1091", "end_pos": "1091" }, { "start_pos": "1144", "end_pos": "1144" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1071", "end_pos": "1071" }, { "start_pos": "1089", "end_pos": "1089" }, { "start_pos": "1098", "end_pos": "1098" }, { "start_pos": "1148", "end_pos": "1148" }, { "start_pos": "1151", "end_pos": "1151" }, { "start_pos": "1163", "end_pos": "1163" }, { "start_pos": "1165", "end_pos": "1165" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1242", "end_pos": "1242" }, { "start_pos": "1303", "end_pos": "1303" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "536", "end_pos": "536" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "616", "end_pos": "616" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "671", "end_pos": "671" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "678", "end_pos": "678" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "819", "end_pos": "819" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "911", "end_pos": "911" }, { "start_pos": "965", "end_pos": "965" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "P81122-1.965.965", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q3HNM7-1.74.74", "start_pos": 74, "end_pos": 74, "uniprot_canonical_ac": "Q3HNM7-1", "length": 579, "uniprot_id": "INSC_MOUSE", "protein_name": "Protein inscuteable homolog", "refseq_ac": "NP_776128", "refseq_name": "protein inscuteable homolog isoform 2", "gene_name": "Insc", "gene_names_uniprotkb": "Insc", "gene_names_refseq": "3830422K02Rik; C730020D23; Insc", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3HNM7", "url": "https://www.uniprot.org/uniprotkb/Q3HNM7" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "LGN/mInsc and LGN/NuMA complex structures suggest distinct functions in asymmetric cell division for the Par3/mInsc/LGN and Galphai/LGN/NuMA pathways.", "journal": "Molecular cell", "date": "2011", "authors": "Zhu J, Wen W, Zheng Z, Shang Y, Wei Z, Xiao Z, Pan Z, Du Q, Wang W, Zhang M", "evidence": [ { "database": "UniProtKB", "id": "Q3HNM7", "url": "https://www.uniprot.org/uniprotkb/Q3HNM7" } ], "reference": [ { "type": "PubMed", "id": "21816348", "url": "https://glygen.org/publication/PubMed/21816348" } ] } ], "crossref": [ { "id": "Q3HNM7", "url": "https://www.uniprot.org/uniprotkb/Q3HNM7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21816348", "url": "https://glygen.org/publication/PubMed/21816348", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GRHLDSVPLQEQRLHFMQVD", "down_seq": "VQRWMEDLKLMTECECMCVL", "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "E", "comment": "Abolishes interaction with GPSM2.", "evidence": [ { "database": "UniProtKB", "id": "Q3HNM7", "url": "https://www.uniprot.org/uniprotkb/Q3HNM7" }, { "database": "PubMed", "id": "21816348", "url": "https://glygen.org/publication/PubMed/21816348" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "74", "end_pos": "74" }, { "start_pos": "78", "end_pos": "78" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "82", "end_pos": "82" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "Q3HNM7-1.78.78", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q3HNM7-1.79.79", "categories": [ "mutagenesis_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q3HNM7-1.82.82", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q3HNM7-1.78.78", "start_pos": 78, "end_pos": 78, "uniprot_canonical_ac": "Q3HNM7-1", "length": 579, "uniprot_id": "INSC_MOUSE", "protein_name": "Protein inscuteable homolog", "refseq_ac": "NP_776128", "refseq_name": "protein inscuteable homolog isoform 2", "gene_name": "Insc", "gene_names_uniprotkb": "Insc", "gene_names_refseq": "3830422K02Rik; C730020D23; Insc", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3HNM7", "url": "https://www.uniprot.org/uniprotkb/Q3HNM7" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "LGN/mInsc and LGN/NuMA complex structures suggest distinct functions in asymmetric cell division for the Par3/mInsc/LGN and Galphai/LGN/NuMA pathways.", "journal": "Molecular cell", "date": "2011", "authors": "Zhu J, Wen W, Zheng Z, Shang Y, Wei Z, Xiao Z, Pan Z, Du Q, Wang W, Zhang M", "evidence": [ { "database": "UniProtKB", "id": "Q3HNM7", "url": "https://www.uniprot.org/uniprotkb/Q3HNM7" } ], "reference": [ { "type": "PubMed", "id": "21816348", "url": "https://glygen.org/publication/PubMed/21816348" } ] } ], "crossref": [ { "id": "Q3HNM7", "url": "https://www.uniprot.org/uniprotkb/Q3HNM7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21816348", "url": "https://glygen.org/publication/PubMed/21816348", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "W", "start_aa": "W", "up_seq": "DSVPLQEQRLHFMQVDSVQR", "down_seq": "MEDLKLMTECECMCVLQAKP", "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "E", "comment": "Abolishes interaction with GPSM2.", "evidence": [ { "database": "UniProtKB", "id": "Q3HNM7", "url": "https://www.uniprot.org/uniprotkb/Q3HNM7" }, { "database": "PubMed", "id": "21816348", "url": "https://glygen.org/publication/PubMed/21816348" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "74", "end_pos": "74" }, { "start_pos": "78", "end_pos": "78" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "82", "end_pos": "82" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "Q3HNM7-1.74.74", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q3HNM7-1.79.79", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q3HNM7-1.82.82", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q3HNM7-1.79.79", "start_pos": 79, "end_pos": 79, "uniprot_canonical_ac": "Q3HNM7-1", "length": 579, "uniprot_id": "INSC_MOUSE", "protein_name": "Protein inscuteable homolog", "refseq_ac": "NP_776128", "refseq_name": "protein inscuteable homolog isoform 2", "gene_name": "Insc", "gene_names_uniprotkb": "Insc", "gene_names_refseq": "3830422K02Rik; C730020D23; Insc", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3HNM7", "url": "https://www.uniprot.org/uniprotkb/Q3HNM7" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "LGN/mInsc and LGN/NuMA complex structures suggest distinct functions in asymmetric cell division for the Par3/mInsc/LGN and Galphai/LGN/NuMA pathways.", "journal": "Molecular cell", "date": "2011", "authors": "Zhu J, Wen W, Zheng Z, Shang Y, Wei Z, Xiao Z, Pan Z, Du Q, Wang W, Zhang M", "evidence": [ { "database": "UniProtKB", "id": "Q3HNM7", "url": "https://www.uniprot.org/uniprotkb/Q3HNM7" } ], "reference": [ { "type": "PubMed", "id": "21816348", "url": "https://glygen.org/publication/PubMed/21816348" } ] } ], "crossref": [ { "id": "Q3HNM7", "url": "https://www.uniprot.org/uniprotkb/Q3HNM7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21816348", "url": "https://glygen.org/publication/PubMed/21816348", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "M", "start_aa": "M", "up_seq": "SVPLQEQRLHFMQVDSVQRW", "down_seq": "EDLKLMTECECMCVLQAKPI", "mutagenesis": [ { "sequence_org": "M", "sequence_mut": "E", "comment": "Abolishes interaction with GPSM2.", "evidence": [ { "database": "UniProtKB", "id": "Q3HNM7", "url": "https://www.uniprot.org/uniprotkb/Q3HNM7" }, { "database": "PubMed", "id": "21816348", "url": "https://glygen.org/publication/PubMed/21816348" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "74", "end_pos": "74" }, { "start_pos": "78", "end_pos": "78" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "82", "end_pos": "82" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "Q3HNM7-1.74.74", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q3HNM7-1.78.78", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q3HNM7-1.82.82", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q3HNM7-1.82.82", "start_pos": 82, "end_pos": 82, "uniprot_canonical_ac": "Q3HNM7-1", "length": 579, "uniprot_id": "INSC_MOUSE", "protein_name": "Protein inscuteable homolog", "refseq_ac": "NP_776128", "refseq_name": "protein inscuteable homolog isoform 2", "gene_name": "Insc", "gene_names_uniprotkb": "Insc", "gene_names_refseq": "3830422K02Rik; C730020D23; Insc", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3HNM7", "url": "https://www.uniprot.org/uniprotkb/Q3HNM7" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "LGN/mInsc and LGN/NuMA complex structures suggest distinct functions in asymmetric cell division for the Par3/mInsc/LGN and Galphai/LGN/NuMA pathways.", "journal": "Molecular cell", "date": "2011", "authors": "Zhu J, Wen W, Zheng Z, Shang Y, Wei Z, Xiao Z, Pan Z, Du Q, Wang W, Zhang M", "evidence": [ { "database": "UniProtKB", "id": "Q3HNM7", "url": "https://www.uniprot.org/uniprotkb/Q3HNM7" } ], "reference": [ { "type": "PubMed", "id": "21816348", "url": "https://glygen.org/publication/PubMed/21816348" } ] } ], "crossref": [ { "id": "Q3HNM7", "url": "https://www.uniprot.org/uniprotkb/Q3HNM7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21816348", "url": "https://glygen.org/publication/PubMed/21816348", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "L", "start_aa": "L", "up_seq": "LQEQRLHFMQVDSVQRWMED", "down_seq": "KLMTECECMCVLQAKPISLE", "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "E", "comment": "Abolishes interaction with GPSM2.", "evidence": [ { "database": "UniProtKB", "id": "Q3HNM7", "url": "https://www.uniprot.org/uniprotkb/Q3HNM7" }, { "database": "PubMed", "id": "21816348", "url": "https://glygen.org/publication/PubMed/21816348" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "74", "end_pos": "74" }, { "start_pos": "78", "end_pos": "78" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "82", "end_pos": "82" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "Q3HNM7-1.74.74", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q3HNM7-1.78.78", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q3HNM7-1.79.79", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6PDM4-1.476.476", "start_pos": 476, "end_pos": 476, "uniprot_canonical_ac": "Q6PDM4-1", "length": 574, "uniprot_id": "IHO1_MOUSE", "protein_name": "Interactor of HORMAD1 protein 1", "refseq_ac": "NP_001128670", "refseq_name": "interactor of HORMAD1 protein 1 isoform 1", "gene_name": "Iho1", "gene_names_uniprotkb": "Iho1; Ccdc36", "gene_names_refseq": "Ccdc36; Iho1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6PDM4", "url": "https://www.uniprot.org/uniprotkb/Q6PDM4" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q6PDM4", "url": "https://www.uniprot.org/uniprotkb/Q6PDM4" }, { "database": "iPTMnet", "id": "Q6PDM4", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6PDM4" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q6PDM4", "url": "https://www.uniprot.org/uniprotkb/Q6PDM4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q6PDM4", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6PDM4", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KQGQTSKAACAFIARHHCPQ", "down_seq": "PVCDPQGPLICWLTPRSSTK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q6PDM4", "url": "https://www.uniprot.org/uniprotkb/Q6PDM4" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q6PDM4", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6PDM4" } ], "site_lbl": "Ser476" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "476", "end_pos": "476" }, { "start_pos": "569", "end_pos": "569" }, { "start_pos": "570", "end_pos": "570" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6PDM4-1.569.569", "start_pos": 569, "end_pos": 569, "uniprot_canonical_ac": "Q6PDM4-1", "length": 574, "uniprot_id": "IHO1_MOUSE", "protein_name": "Interactor of HORMAD1 protein 1", "refseq_ac": "NP_001128670", "refseq_name": "interactor of HORMAD1 protein 1 isoform 1", "gene_name": "Iho1", "gene_names_uniprotkb": "Iho1; Ccdc36", "gene_names_refseq": "Ccdc36; Iho1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6PDM4", "url": "https://www.uniprot.org/uniprotkb/Q6PDM4" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q6PDM4", "url": "https://www.uniprot.org/uniprotkb/Q6PDM4" }, { "database": "iPTMnet", "id": "Q6PDM4", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6PDM4" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q6PDM4", "url": "https://www.uniprot.org/uniprotkb/Q6PDM4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q6PDM4", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6PDM4", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LEPPQCKKGGTNLLCDPDFD", "down_seq": "SDDNF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q6PDM4", "url": "https://www.uniprot.org/uniprotkb/Q6PDM4" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q6PDM4", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6PDM4" } ], "site_lbl": "Ser569" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "476", "end_pos": "476" }, { "start_pos": "569", "end_pos": "569" }, { "start_pos": "570", "end_pos": "570" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "Q6PDM4-1.570.570", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6PDM4-1.570.570", "start_pos": 570, "end_pos": 570, "uniprot_canonical_ac": "Q6PDM4-1", "length": 574, "uniprot_id": "IHO1_MOUSE", "protein_name": "Interactor of HORMAD1 protein 1", "refseq_ac": "NP_001128670", "refseq_name": "interactor of HORMAD1 protein 1 isoform 1", "gene_name": "Iho1", "gene_names_uniprotkb": "Iho1; Ccdc36", "gene_names_refseq": "Ccdc36; Iho1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6PDM4", "url": "https://www.uniprot.org/uniprotkb/Q6PDM4" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q6PDM4", "url": "https://www.uniprot.org/uniprotkb/Q6PDM4" }, { "database": "iPTMnet", "id": "Q6PDM4", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6PDM4" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q6PDM4", "url": "https://www.uniprot.org/uniprotkb/Q6PDM4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q6PDM4", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6PDM4", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EPPQCKKGGTNLLCDPDFDS", "down_seq": "DDNF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q6PDM4", "url": "https://www.uniprot.org/uniprotkb/Q6PDM4" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q6PDM4", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6PDM4" } ], "site_lbl": "Ser570" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "476", "end_pos": "476" }, { "start_pos": "569", "end_pos": "569" }, { "start_pos": "570", "end_pos": "570" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "Q6PDM4-1.569.569", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P70671-1.111.111", "start_pos": 111, "end_pos": 111, "uniprot_canonical_ac": "P70671-1", "length": 419, "uniprot_id": "IRF3_MOUSE", "protein_name": "Interferon regulatory factor 3", "refseq_ac": "NP_058545", "refseq_name": "interferon regulatory factor 3", "gene_name": "Irf3", "gene_names_uniprotkb": "Irf3", "gene_names_refseq": "C920001K05Rik; IRF-3; Irf3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "RLAADNSKDPYDPHKVYEFV", "down_seq": "PGARDFVHLGASPDTNGKSS", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr111", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "111", "end_pos": "111" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "152", "end_pos": "152" }, { "start_pos": "359", "end_pos": "359" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "68", "end_pos": "68" }, { "start_pos": "70", "end_pos": "70" }, { "start_pos": "85", "end_pos": "85" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "123", "end_pos": "123" }, { "start_pos": "135", "end_pos": "135" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "378", "end_pos": "378" }, { "start_pos": "379", "end_pos": "379" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "390", "end_pos": "390" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "97", "end_pos": "97" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "P70671-1.97.97", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P70671-1.107.107", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P70671-1.123.123", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P70671-1.152.152", "start_pos": 152, "end_pos": 152, "uniprot_canonical_ac": "P70671-1", "length": 419, "uniprot_id": "IRF3_MOUSE", "protein_name": "Interferon regulatory factor 3", "refseq_ac": "NP_058545", "refseq_name": "interferon regulatory factor 3", "gene_name": "Irf3", "gene_names_uniprotkb": "Irf3", "gene_names_refseq": "C920001K05Rik; IRF-3; Irf3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "KAT8 selectively inhibits antiviral immunity by acetylating IRF3.", "journal": "The Journal of experimental medicine", "date": "2019", "authors": "Huai W, Liu X, Wang C, Zhang Y, Chen X, Chen X, Xu S, Thomas T, Li N, Cao X", "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" } ], "reference": [ { "type": "PubMed", "id": "30842237", "url": "https://glygen.org/publication/PubMed/30842237" } ] } ], "crossref": [ { "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "30842237", "url": "https://glygen.org/publication/PubMed/30842237", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "LPHSQENLPKLFDGLILGPL", "down_seq": "DEGSSDLAIVSDPSQQLPSP", "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Does not affect acetylation by KAT8.", "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" }, { "database": "PubMed", "id": "30842237", "url": "https://glygen.org/publication/PubMed/30842237" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "111", "end_pos": "111" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "152", "end_pos": "152" }, { "start_pos": "359", "end_pos": "359" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "68", "end_pos": "68" }, { "start_pos": "70", "end_pos": "70" }, { "start_pos": "85", "end_pos": "85" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "123", "end_pos": "123" }, { "start_pos": "135", "end_pos": "135" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "378", "end_pos": "378" }, { "start_pos": "379", "end_pos": "379" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "390", "end_pos": "390" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "97", "end_pos": "97" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P70671-1.135.135", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P70671-1.359.359", "start_pos": 359, "end_pos": 359, "uniprot_canonical_ac": "P70671-1", "length": 419, "uniprot_id": "IRF3_MOUSE", "protein_name": "Interferon regulatory factor 3", "refseq_ac": "NP_058545", "refseq_name": "interferon regulatory factor 3", "gene_name": "Irf3", "gene_names_uniprotkb": "Irf3", "gene_names_refseq": "C920001K05Rik; IRF-3; Irf3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "KAT8 selectively inhibits antiviral immunity by acetylating IRF3.", "journal": "The Journal of experimental medicine", "date": "2019", "authors": "Huai W, Liu X, Wang C, Zhang Y, Chen X, Chen X, Xu S, Thomas T, Li N, Cao X", "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" } ], "reference": [ { "type": "PubMed", "id": "30842237", "url": "https://glygen.org/publication/PubMed/30842237" } ] } ], "crossref": [ { "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "30842237", "url": "https://glygen.org/publication/PubMed/30842237", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "FCMGEMWPQDQPWVKRLVMV", "down_seq": "VVPTCLKELLEMAREGGASS", "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Abolished acetylation by KAT8, leading to increased transcription factor activity.", "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" }, { "database": "PubMed", "id": "30842237", "url": "https://glygen.org/publication/PubMed/30842237" } ] }, { "sequence_org": "K", "sequence_mut": "R", "comment": "Abolished acetylation by KAT8, leading to increased transcription factor activity.", "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" }, { "database": "PubMed", "id": "30842237", "url": "https://glygen.org/publication/PubMed/30842237" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "111", "end_pos": "111" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "152", "end_pos": "152" }, { "start_pos": "359", "end_pos": "359" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "68", "end_pos": "68" }, { "start_pos": "70", "end_pos": "70" }, { "start_pos": "85", "end_pos": "85" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "123", "end_pos": "123" }, { "start_pos": "135", "end_pos": "135" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "378", "end_pos": "378" }, { "start_pos": "379", "end_pos": "379" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "390", "end_pos": "390" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "97", "end_pos": "97" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "upstream", "id": "P70671-1.378.378", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P70671-1.379.379", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P70671-1.388.388", "start_pos": 388, "end_pos": 388, "uniprot_canonical_ac": "P70671-1", "length": 419, "uniprot_id": "IRF3_MOUSE", "protein_name": "Interferon regulatory factor 3", "refseq_ac": "NP_058545", "refseq_name": "interferon regulatory factor 3", "gene_name": "Irf3", "gene_names_uniprotkb": "Irf3", "gene_names_refseq": "C920001K05Rik; IRF-3; Irf3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "KAT8 selectively inhibits antiviral immunity by acetylating IRF3.", "journal": "The Journal of experimental medicine", "date": "2019", "authors": "Huai W, Liu X, Wang C, Zhang Y, Chen X, Chen X, Xu S, Thomas T, Li N, Cao X", "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" } ], "reference": [ { "type": "PubMed", "id": "30842237", "url": "https://glygen.org/publication/PubMed/30842237" } ] } ], "crossref": [ { "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "30842237", "url": "https://glygen.org/publication/PubMed/30842237", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LLEMAREGGASSLKTVDLHI", "down_seq": "NSQPISLTSDQYKAYLQDLV", "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Decreased acetylation by KAT8.", "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" }, { "database": "PubMed", "id": "30842237", "url": "https://glygen.org/publication/PubMed/30842237" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by IKKE", "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" } ], "site_lbl": "Ser388" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "111", "end_pos": "111" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "152", "end_pos": "152" }, { "start_pos": "359", "end_pos": "359" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "68", "end_pos": "68" }, { "start_pos": "70", "end_pos": "70" }, { "start_pos": "85", "end_pos": "85" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "123", "end_pos": "123" }, { "start_pos": "135", "end_pos": "135" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "378", "end_pos": "378" }, { "start_pos": "379", "end_pos": "379" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "390", "end_pos": "390" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "97", "end_pos": "97" } ] } ], "categories": [ "mutagenesis_flag", "phosphorylation_flag" ], "glycosylation": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "P70671-1.378.378", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P70671-1.379.379", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P70671-1.389.389", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P70671-1.390.390", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P70671-1.396.396", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P70671-1.389.389", "start_pos": 389, "end_pos": 389, "uniprot_canonical_ac": "P70671-1", "length": 419, "uniprot_id": "IRF3_MOUSE", "protein_name": "Interferon regulatory factor 3", "refseq_ac": "NP_058545", "refseq_name": "interferon regulatory factor 3", "gene_name": "Irf3", "gene_names_uniprotkb": "Irf3", "gene_names_refseq": "C920001K05Rik; IRF-3; Irf3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Pyrimidine synthesis enzyme CTP synthetase 1 suppresses antiviral interferon induction by deamidating IRF3.", "journal": "Immunity", "date": "2025-01-14", "authors": "Rao Youliang, Qin Chao, Savas Ali Can, Liu Qizhi, Feng Shu, Hou Guoli, Xie Taolin, Feng Pinghui", "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" } ], "reference": [ { "type": "PubMed", "id": "39719712", "url": "https://glygen.org/publication/PubMed/39719712" } ] } ], "crossref": [ { "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "39719712", "url": "https://glygen.org/publication/PubMed/39719712", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "LEMAREGGASSLKTVDLHIS", "down_seq": "SQPISLTSDQYKAYLQDLVE", "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "D", "comment": "Does not affect ability to bind DNA.", "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" }, { "database": "PubMed", "id": "39719712", "url": "https://glygen.org/publication/PubMed/39719712" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "111", "end_pos": "111" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "152", "end_pos": "152" }, { "start_pos": "359", "end_pos": "359" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "68", "end_pos": "68" }, { "start_pos": "70", "end_pos": "70" }, { "start_pos": "85", "end_pos": "85" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "123", "end_pos": "123" }, { "start_pos": "135", "end_pos": "135" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "378", "end_pos": "378" }, { "start_pos": "379", "end_pos": "379" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "390", "end_pos": "390" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "97", "end_pos": "97" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "P70671-1.378.378", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P70671-1.379.379", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P70671-1.388.388", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P70671-1.390.390", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P70671-1.396.396", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P70671-1.68.68", "start_pos": 68, "end_pos": 68, "uniprot_canonical_ac": "P70671-1", "length": 419, "uniprot_id": "IRF3_MOUSE", "protein_name": "Interferon regulatory factor 3", "refseq_ac": "NP_058545", "refseq_name": "interferon regulatory factor 3", "gene_name": "Irf3", "gene_names_uniprotkb": "Irf3", "gene_names_refseq": "C920001K05Rik; IRF-3; Irf3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "KAT8 selectively inhibits antiviral immunity by acetylating IRF3.", "journal": "The Journal of experimental medicine", "date": "2019", "authors": "Huai W, Liu X, Wang C, Zhang Y, Chen X, Chen X, Xu S, Thomas T, Li N, Cao X", "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" } ], "reference": [ { "type": "PubMed", "id": "30842237", "url": "https://glygen.org/publication/PubMed/30842237" } ] } ], "crossref": [ { "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "30842237", "url": "https://glygen.org/publication/PubMed/30842237", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "MADFGIFQAWAEASGAYTPG", "down_seq": "DKPDVSTWKRNFRSALNRKE", "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Does not affect acetylation by KAT8.", "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" }, { "database": "PubMed", "id": "30842237", "url": "https://glygen.org/publication/PubMed/30842237" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "111", "end_pos": "111" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "152", "end_pos": "152" }, { "start_pos": "359", "end_pos": "359" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "68", "end_pos": "68" }, { "start_pos": "70", "end_pos": "70" }, { "start_pos": "85", "end_pos": "85" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "123", "end_pos": "123" }, { "start_pos": "135", "end_pos": "135" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "378", "end_pos": "378" }, { "start_pos": "379", "end_pos": "379" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "390", "end_pos": "390" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "97", "end_pos": "97" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P70671-1.70.70", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P70671-1.75.75", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P70671-1.85.85", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P70671-1.70.70", "start_pos": 70, "end_pos": 70, "uniprot_canonical_ac": "P70671-1", "length": 419, "uniprot_id": "IRF3_MOUSE", "protein_name": "Interferon regulatory factor 3", "refseq_ac": "NP_058545", "refseq_name": "interferon regulatory factor 3", "gene_name": "Irf3", "gene_names_uniprotkb": "Irf3", "gene_names_refseq": "C920001K05Rik; IRF-3; Irf3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "KAT8 selectively inhibits antiviral immunity by acetylating IRF3.", "journal": "The Journal of experimental medicine", "date": "2019", "authors": "Huai W, Liu X, Wang C, Zhang Y, Chen X, Chen X, Xu S, Thomas T, Li N, Cao X", "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" } ], "reference": [ { "type": "PubMed", "id": "30842237", "url": "https://glygen.org/publication/PubMed/30842237" } ] } ], "crossref": [ { "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "30842237", "url": "https://glygen.org/publication/PubMed/30842237", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "DFGIFQAWAEASGAYTPGKD", "down_seq": "PDVSTWKRNFRSALNRKEVL", "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Does not affect acetylation by KAT8.", "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" }, { "database": "PubMed", "id": "30842237", "url": "https://glygen.org/publication/PubMed/30842237" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "111", "end_pos": "111" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "152", "end_pos": "152" }, { "start_pos": "359", "end_pos": "359" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "68", "end_pos": "68" }, { "start_pos": "70", "end_pos": "70" }, { "start_pos": "85", "end_pos": "85" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "123", "end_pos": "123" }, { "start_pos": "135", "end_pos": "135" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "378", "end_pos": "378" }, { "start_pos": "379", "end_pos": "379" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "390", "end_pos": "390" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "97", "end_pos": "97" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P70671-1.68.68", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P70671-1.75.75", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P70671-1.85.85", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P70671-1.85.85", "start_pos": 85, "end_pos": 85, "uniprot_canonical_ac": "P70671-1", "length": 419, "uniprot_id": "IRF3_MOUSE", "protein_name": "Interferon regulatory factor 3", "refseq_ac": "NP_058545", "refseq_name": "interferon regulatory factor 3", "gene_name": "Irf3", "gene_names_uniprotkb": "Irf3", "gene_names_refseq": "C920001K05Rik; IRF-3; Irf3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Pyrimidine synthesis enzyme CTP synthetase 1 suppresses antiviral interferon induction by deamidating IRF3.", "journal": "Immunity", "date": "2025-01-14", "authors": "Rao Youliang, Qin Chao, Savas Ali Can, Liu Qizhi, Feng Shu, Hou Guoli, Xie Taolin, Feng Pinghui", "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" } ], "reference": [ { "type": "PubMed", "id": "39719712", "url": "https://glygen.org/publication/PubMed/39719712" } ] } ], "crossref": [ { "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "39719712", "url": "https://glygen.org/publication/PubMed/39719712", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "TPGKDKPDVSTWKRNFRSAL", "down_seq": "RKEVLRLAADNSKDPYDPHK", "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "D", "comment": "Impaired ability to bind DNA and act as a transcription factor.", "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" }, { "database": "PubMed", "id": "39719712", "url": "https://glygen.org/publication/PubMed/39719712" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "111", "end_pos": "111" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "152", "end_pos": "152" }, { "start_pos": "359", "end_pos": "359" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "68", "end_pos": "68" }, { "start_pos": "70", "end_pos": "70" }, { "start_pos": "85", "end_pos": "85" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "123", "end_pos": "123" }, { "start_pos": "135", "end_pos": "135" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "378", "end_pos": "378" }, { "start_pos": "379", "end_pos": "379" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "390", "end_pos": "390" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "97", "end_pos": "97" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P70671-1.68.68", "categories": [ "mutagenesis_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P70671-1.70.70", "categories": [ "mutagenesis_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P70671-1.75.75", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P70671-1.97.97", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P70671-1.107.107", "start_pos": 107, "end_pos": 107, "uniprot_canonical_ac": "P70671-1", "length": 419, "uniprot_id": "IRF3_MOUSE", "protein_name": "Interferon regulatory factor 3", "refseq_ac": "NP_058545", "refseq_name": "interferon regulatory factor 3", "gene_name": "Irf3", "gene_names_uniprotkb": "Irf3", "gene_names_refseq": "C920001K05Rik; IRF-3; Irf3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Modulation of innate immune response to viruses including SARS-CoV-2 by progesterone.", "journal": "Signal transduction and targeted therapy", "date": "2022-04-25", "authors": "Su Shan, Hua Duo, Li Jin-Peng, Zhang Xia-Nan, Bai Lei, Cao Li-Bo, Guo Yi, Zhang Ming, Dong Jia-Zhen, Liang Xiao-Wei, Lan Ke, Hu Ming-Ming, Shu Hong-Bing", "evidence": [ { "database": "iPTMnet", "id": "P70671", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P70671" } ], "reference": [ { "type": "PubMed", "id": "35468896", "url": "https://glygen.org/publication/PubMed/35468896" } ] } ], "crossref": [ { "id": "P70671", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P70671", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "35468896", "url": "https://glygen.org/publication/PubMed/35468896", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "KEVLRLAADNSKDPYDPHKV", "down_seq": "EFVTPGARDFVHLGASPDTN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P70671", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P70671" }, { "database": "PubMed", "id": "35468896", "url": "https://glygen.org/publication/PubMed/35468896" } ], "site_lbl": "Tyr107" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "111", "end_pos": "111" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "152", "end_pos": "152" }, { "start_pos": "359", "end_pos": "359" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "68", "end_pos": "68" }, { "start_pos": "70", "end_pos": "70" }, { "start_pos": "85", "end_pos": "85" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "123", "end_pos": "123" }, { "start_pos": "135", "end_pos": "135" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "378", "end_pos": "378" }, { "start_pos": "379", "end_pos": "379" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "390", "end_pos": "390" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "97", "end_pos": "97" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "P70671-1.97.97", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P70671-1.111.111", "categories": [ "glycosylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P70671-1.123.123", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P70671-1.123.123", "start_pos": 123, "end_pos": 123, "uniprot_canonical_ac": "P70671-1", "length": 419, "uniprot_id": "IRF3_MOUSE", "protein_name": "Interferon regulatory factor 3", "refseq_ac": "NP_058545", "refseq_name": "interferon regulatory factor 3", "gene_name": "Irf3", "gene_names_uniprotkb": "Irf3", "gene_names_refseq": "C920001K05Rik; IRF-3; Irf3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" }, { "database": "iPTMnet", "id": "P70671", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P70671" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P70671", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P70671", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PHKVYEFVTPGARDFVHLGA", "down_seq": "PDTNGKSSLPHSQENLPKLF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "P70671", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P70671" } ], "site_lbl": "Ser123" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "111", "end_pos": "111" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "152", "end_pos": "152" }, { "start_pos": "359", "end_pos": "359" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "68", "end_pos": "68" }, { "start_pos": "70", "end_pos": "70" }, { "start_pos": "85", "end_pos": "85" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "123", "end_pos": "123" }, { "start_pos": "135", "end_pos": "135" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "378", "end_pos": "378" }, { "start_pos": "379", "end_pos": "379" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "390", "end_pos": "390" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "97", "end_pos": "97" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P70671-1.107.107", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P70671-1.111.111", "categories": [ "glycosylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P70671-1.135.135", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P70671-1.135.135", "start_pos": 135, "end_pos": 135, "uniprot_canonical_ac": "P70671-1", "length": 419, "uniprot_id": "IRF3_MOUSE", "protein_name": "Interferon regulatory factor 3", "refseq_ac": "NP_058545", "refseq_name": "interferon regulatory factor 3", "gene_name": "Irf3", "gene_names_uniprotkb": "Irf3", "gene_names_refseq": "C920001K05Rik; IRF-3; Irf3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" }, { "database": "iPTMnet", "id": "P70671", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P70671" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P70671", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P70671", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RDFVHLGASPDTNGKSSLPH", "down_seq": "QENLPKLFDGLILGPLKDEG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "P70671", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P70671" } ], "site_lbl": "Ser135" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "111", "end_pos": "111" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "152", "end_pos": "152" }, { "start_pos": "359", "end_pos": "359" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "68", "end_pos": "68" }, { "start_pos": "70", "end_pos": "70" }, { "start_pos": "85", "end_pos": "85" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "123", "end_pos": "123" }, { "start_pos": "135", "end_pos": "135" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "378", "end_pos": "378" }, { "start_pos": "379", "end_pos": "379" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "390", "end_pos": "390" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "97", "end_pos": "97" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "P70671-1.123.123", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P70671-1.152.152", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P70671-1.14.14", "start_pos": 14, "end_pos": 14, "uniprot_canonical_ac": "P70671-1", "length": 419, "uniprot_id": "IRF3_MOUSE", "protein_name": "Interferon regulatory factor 3", "refseq_ac": "NP_058545", "refseq_name": "interferon regulatory factor 3", "gene_name": "Irf3", "gene_names_uniprotkb": "Irf3", "gene_names_refseq": "C920001K05Rik; IRF-3; Irf3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "METPKPRILPWLV", "down_seq": "QLDLGQLEGVAWLDESRTRF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" } ], "site_lbl": "Ser14" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "111", "end_pos": "111" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "152", "end_pos": "152" }, { "start_pos": "359", "end_pos": "359" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "68", "end_pos": "68" }, { "start_pos": "70", "end_pos": "70" }, { "start_pos": "85", "end_pos": "85" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "123", "end_pos": "123" }, { "start_pos": "135", "end_pos": "135" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "378", "end_pos": "378" }, { "start_pos": "379", "end_pos": "379" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "390", "end_pos": "390" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "97", "end_pos": "97" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "P70671-1.3.3", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P70671-1.230.230", "start_pos": 230, "end_pos": 230, "uniprot_canonical_ac": "P70671-1", "length": 419, "uniprot_id": "IRF3_MOUSE", "protein_name": "Interferon regulatory factor 3", "refseq_ac": "NP_058545", "refseq_name": "interferon regulatory factor 3", "gene_name": "Irf3", "gene_names_uniprotkb": "Irf3", "gene_names_refseq": "C920001K05Rik; IRF-3; Irf3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "FQQTLFCPGGLRLVGSTADM", "down_seq": "LPWQPVTLPDPEGFLTDKLV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" } ], "site_lbl": "Thr230" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "111", "end_pos": "111" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "152", "end_pos": "152" }, { "start_pos": "359", "end_pos": "359" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "68", "end_pos": "68" }, { "start_pos": "70", "end_pos": "70" }, { "start_pos": "85", "end_pos": "85" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "123", "end_pos": "123" }, { "start_pos": "135", "end_pos": "135" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "378", "end_pos": "378" }, { "start_pos": "379", "end_pos": "379" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "390", "end_pos": "390" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "97", "end_pos": "97" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "upstream", "id": "P70671-1.237.237", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P70671-1.246.246", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P70671-1.237.237", "start_pos": 237, "end_pos": 237, "uniprot_canonical_ac": "P70671-1", "length": 419, "uniprot_id": "IRF3_MOUSE", "protein_name": "Interferon regulatory factor 3", "refseq_ac": "NP_058545", "refseq_name": "interferon regulatory factor 3", "gene_name": "Irf3", "gene_names_uniprotkb": "Irf3", "gene_names_refseq": "C920001K05Rik; IRF-3; Irf3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "PGGLRLVGSTADMTLPWQPV", "down_seq": "LPDPEGFLTDKLVKEYVGQV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" } ], "site_lbl": "Thr237" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "111", "end_pos": "111" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "152", "end_pos": "152" }, { "start_pos": "359", "end_pos": "359" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "68", "end_pos": "68" }, { "start_pos": "70", "end_pos": "70" }, { "start_pos": "85", "end_pos": "85" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "123", "end_pos": "123" }, { "start_pos": "135", "end_pos": "135" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "378", "end_pos": "378" }, { "start_pos": "379", "end_pos": "379" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "390", "end_pos": "390" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "97", "end_pos": "97" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "P70671-1.230.230", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P70671-1.246.246", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P70671-1.246.246", "start_pos": 246, "end_pos": 246, "uniprot_canonical_ac": "P70671-1", "length": 419, "uniprot_id": "IRF3_MOUSE", "protein_name": "Interferon regulatory factor 3", "refseq_ac": "NP_058545", "refseq_name": "interferon regulatory factor 3", "gene_name": "Irf3", "gene_names_uniprotkb": "Irf3", "gene_names_refseq": "C920001K05Rik; IRF-3; Irf3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "TADMTLPWQPVTLPDPEGFL", "down_seq": "DKLVKEYVGQVLKGLGNGLA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" } ], "site_lbl": "Thr246" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "111", "end_pos": "111" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "152", "end_pos": "152" }, { "start_pos": "359", "end_pos": "359" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "68", "end_pos": "68" }, { "start_pos": "70", "end_pos": "70" }, { "start_pos": "85", "end_pos": "85" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "123", "end_pos": "123" }, { "start_pos": "135", "end_pos": "135" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "378", "end_pos": "378" }, { "start_pos": "379", "end_pos": "379" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "390", "end_pos": "390" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "97", "end_pos": "97" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P70671-1.230.230", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P70671-1.237.237", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P70671-1.378.378", "start_pos": 378, "end_pos": 378, "uniprot_canonical_ac": "P70671-1", "length": 419, "uniprot_id": "IRF3_MOUSE", "protein_name": "Interferon regulatory factor 3", "refseq_ac": "NP_058545", "refseq_name": "interferon regulatory factor 3", "gene_name": "Irf3", "gene_names_uniprotkb": "Irf3", "gene_names_refseq": "C920001K05Rik; IRF-3; Irf3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Identification of Lps2 as a key transducer of MyD88-independent TIR signalling.", "journal": "Nature", "date": "2003", "authors": "Hoebe K, Du X, Georgel P, Janssen E, Tabeta K, Kim SO, Goode J, Lin P, Mann N, Mudd S, Crozat K, Sovath S, Han J, Beutler B", "evidence": [ { "database": "iPTMnet", "id": "P70671-1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P70671-1" } ], "reference": [ { "type": "PubMed", "id": "12872135", "url": "https://glygen.org/publication/PubMed/12872135" } ] } ], "crossref": [ { "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P70671", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P70671", "database": "PRO", "categories": [ "Other" ] }, { "id": "P70671", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P70671", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "12872135", "url": "https://glygen.org/publication/PubMed/12872135", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VKVVPTCLKELLEMAREGGA", "down_seq": "SLKTVDLHISNSQPISLTSD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" }, { "database": "PRO", "id": "P70671", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P70671" }, { "database": "iPTMnet", "id": "P70671", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P70671" }, { "database": "PubMed", "id": "12872135", "url": "https://glygen.org/publication/PubMed/12872135" } ], "site_lbl": "Ser378" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "111", "end_pos": "111" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "152", "end_pos": "152" }, { "start_pos": "359", "end_pos": "359" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "68", "end_pos": "68" }, { "start_pos": "70", "end_pos": "70" }, { "start_pos": "85", "end_pos": "85" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "123", "end_pos": "123" }, { "start_pos": "135", "end_pos": "135" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "378", "end_pos": "378" }, { "start_pos": "379", "end_pos": "379" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "390", "end_pos": "390" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "97", "end_pos": "97" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P70671-1.359.359", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P70671-1.379.379", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P70671-1.388.388", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P70671-1.389.389", "categories": [ "mutagenesis_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P70671-1.390.390", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P70671-1.396.396", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P70671-1.379.379", "start_pos": 379, "end_pos": 379, "uniprot_canonical_ac": "P70671-1", "length": 419, "uniprot_id": "IRF3_MOUSE", "protein_name": "Interferon regulatory factor 3", "refseq_ac": "NP_058545", "refseq_name": "interferon regulatory factor 3", "gene_name": "Irf3", "gene_names_uniprotkb": "Irf3", "gene_names_refseq": "C920001K05Rik; IRF-3; Irf3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Identification of Lps2 as a key transducer of MyD88-independent TIR signalling.", "journal": "Nature", "date": "2003", "authors": "Hoebe K, Du X, Georgel P, Janssen E, Tabeta K, Kim SO, Goode J, Lin P, Mann N, Mudd S, Crozat K, Sovath S, Han J, Beutler B", "evidence": [ { "database": "iPTMnet", "id": "P70671-1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P70671-1" } ], "reference": [ { "type": "PubMed", "id": "12872135", "url": "https://glygen.org/publication/PubMed/12872135" } ] } ], "crossref": [ { "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P70671", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P70671", "database": "PRO", "categories": [ "Other" ] }, { "id": "P70671", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P70671", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "12872135", "url": "https://glygen.org/publication/PubMed/12872135", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KVVPTCLKELLEMAREGGAS", "down_seq": "LKTVDLHISNSQPISLTSDQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by TBK1", "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" }, { "database": "PRO", "id": "P70671", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P70671" }, { "database": "iPTMnet", "id": "P70671", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P70671" }, { "database": "PubMed", "id": "12872135", "url": "https://glygen.org/publication/PubMed/12872135" } ], "site_lbl": "Ser379" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "111", "end_pos": "111" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "152", "end_pos": "152" }, { "start_pos": "359", "end_pos": "359" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "68", "end_pos": "68" }, { "start_pos": "70", "end_pos": "70" }, { "start_pos": "85", "end_pos": "85" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "123", "end_pos": "123" }, { "start_pos": "135", "end_pos": "135" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "378", "end_pos": "378" }, { "start_pos": "379", "end_pos": "379" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "390", "end_pos": "390" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "97", "end_pos": "97" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P70671-1.359.359", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P70671-1.378.378", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P70671-1.388.388", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P70671-1.389.389", "categories": [ "mutagenesis_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P70671-1.390.390", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P70671-1.396.396", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P70671-1.390.390", "start_pos": 390, "end_pos": 390, "uniprot_canonical_ac": "P70671-1", "length": 419, "uniprot_id": "IRF3_MOUSE", "protein_name": "Interferon regulatory factor 3", "refseq_ac": "NP_058545", "refseq_name": "interferon regulatory factor 3", "gene_name": "Irf3", "gene_names_uniprotkb": "Irf3", "gene_names_refseq": "C920001K05Rik; IRF-3; Irf3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EMAREGGASSLKTVDLHISN", "down_seq": "QPISLTSDQYKAYLQDLVED", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" } ], "site_lbl": "Ser390" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "111", "end_pos": "111" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "152", "end_pos": "152" }, { "start_pos": "359", "end_pos": "359" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "68", "end_pos": "68" }, { "start_pos": "70", "end_pos": "70" }, { "start_pos": "85", "end_pos": "85" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "123", "end_pos": "123" }, { "start_pos": "135", "end_pos": "135" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "378", "end_pos": "378" }, { "start_pos": "379", "end_pos": "379" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "390", "end_pos": "390" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "97", "end_pos": "97" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "P70671-1.378.378", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P70671-1.379.379", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P70671-1.388.388", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P70671-1.389.389", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P70671-1.396.396", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P70671-1.396.396", "start_pos": 396, "end_pos": 396, "uniprot_canonical_ac": "P70671-1", "length": 419, "uniprot_id": "IRF3_MOUSE", "protein_name": "Interferon regulatory factor 3", "refseq_ac": "NP_058545", "refseq_name": "interferon regulatory factor 3", "gene_name": "Irf3", "gene_names_uniprotkb": "Irf3", "gene_names_refseq": "C920001K05Rik; IRF-3; Irf3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "GASSLKTVDLHISNSQPISL", "down_seq": "SDQYKAYLQDLVEDMDFQAT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" } ], "site_lbl": "Thr396" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "111", "end_pos": "111" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "152", "end_pos": "152" }, { "start_pos": "359", "end_pos": "359" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "68", "end_pos": "68" }, { "start_pos": "70", "end_pos": "70" }, { "start_pos": "85", "end_pos": "85" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "123", "end_pos": "123" }, { "start_pos": "135", "end_pos": "135" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "378", "end_pos": "378" }, { "start_pos": "379", "end_pos": "379" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "390", "end_pos": "390" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "97", "end_pos": "97" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P70671-1.378.378", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "downstream", "id": "P70671-1.379.379", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P70671-1.388.388", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P70671-1.389.389", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P70671-1.390.390", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P70671-1.3.3", "start_pos": 3, "end_pos": 3, "uniprot_canonical_ac": "P70671-1", "length": 419, "uniprot_id": "IRF3_MOUSE", "protein_name": "Interferon regulatory factor 3", "refseq_ac": "NP_058545", "refseq_name": "interferon regulatory factor 3", "gene_name": "Irf3", "gene_names_uniprotkb": "Irf3", "gene_names_refseq": "C920001K05Rik; IRF-3; Irf3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "ME", "down_seq": "PKPRILPWLVSQLDLGQLEG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" } ], "site_lbl": "Thr3" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "111", "end_pos": "111" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "152", "end_pos": "152" }, { "start_pos": "359", "end_pos": "359" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "68", "end_pos": "68" }, { "start_pos": "70", "end_pos": "70" }, { "start_pos": "85", "end_pos": "85" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "123", "end_pos": "123" }, { "start_pos": "135", "end_pos": "135" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "378", "end_pos": "378" }, { "start_pos": "379", "end_pos": "379" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "390", "end_pos": "390" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "97", "end_pos": "97" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "upstream", "id": "P70671-1.14.14", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P70671-1.75.75", "start_pos": 75, "end_pos": 75, "uniprot_canonical_ac": "P70671-1", "length": 419, "uniprot_id": "IRF3_MOUSE", "protein_name": "Interferon regulatory factor 3", "refseq_ac": "NP_058545", "refseq_name": "interferon regulatory factor 3", "gene_name": "Irf3", "gene_names_uniprotkb": "Irf3", "gene_names_refseq": "C920001K05Rik; IRF-3; Irf3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "QAWAEASGAYTPGKDKPDVS", "down_seq": "WKRNFRSALNRKEVLRLAAD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" } ], "site_lbl": "Thr75" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "111", "end_pos": "111" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "152", "end_pos": "152" }, { "start_pos": "359", "end_pos": "359" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "68", "end_pos": "68" }, { "start_pos": "70", "end_pos": "70" }, { "start_pos": "85", "end_pos": "85" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "123", "end_pos": "123" }, { "start_pos": "135", "end_pos": "135" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "378", "end_pos": "378" }, { "start_pos": "379", "end_pos": "379" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "390", "end_pos": "390" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "97", "end_pos": "97" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "P70671-1.68.68", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P70671-1.70.70", "categories": [ "mutagenesis_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P70671-1.85.85", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P70671-1.97.97", "start_pos": 97, "end_pos": 97, "uniprot_canonical_ac": "P70671-1", "length": 419, "uniprot_id": "IRF3_MOUSE", "protein_name": "Interferon regulatory factor 3", "refseq_ac": "NP_058545", "refseq_name": "interferon regulatory factor 3", "gene_name": "Irf3", "gene_names_uniprotkb": "Irf3", "gene_names_refseq": "C920001K05Rik; IRF-3; Irf3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KRNFRSALNRKEVLRLAADN", "down_seq": "KDPYDPHKVYEFVTPGARDF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P70671", "url": "https://www.uniprot.org/uniprotkb/P70671" } ], "site_lbl": "Ser97" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "111", "end_pos": "111" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "152", "end_pos": "152" }, { "start_pos": "359", "end_pos": "359" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "68", "end_pos": "68" }, { "start_pos": "70", "end_pos": "70" }, { "start_pos": "85", "end_pos": "85" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "123", "end_pos": "123" }, { "start_pos": "135", "end_pos": "135" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "378", "end_pos": "378" }, { "start_pos": "379", "end_pos": "379" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "390", "end_pos": "390" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "97", "end_pos": "97" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "P70671-1.85.85", "categories": [ "mutagenesis_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P70671-1.107.107", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P70671-1.111.111", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9Z307-1.358.358", "start_pos": 358, "end_pos": 358, "uniprot_canonical_ac": "Q9Z307-1", "length": 419, "uniprot_id": "KCJ16_MOUSE", "protein_name": "Inward rectifier potassium channel 16", "refseq_ac": "NP_001239136", "refseq_name": "inward rectifier potassium channel 16", "gene_name": "Kcnj16", "gene_names_uniprotkb": "Kcnj16", "gene_names_refseq": "6430410F18Rik; Kcnj16; Kir5.1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9Z307", "url": "https://www.uniprot.org/uniprotkb/Q9Z307" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9Z307", "url": "https://www.uniprot.org/uniprotkb/Q9Z307" }, { "database": "iPTMnet", "id": "Q9Z307", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9Z307" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q9Z307", "url": "https://www.uniprot.org/uniprotkb/Q9Z307", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9Z307", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9Z307", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "FCSAKQLDWKDQQLNNLEKT", "down_seq": "PARGSCNSDTNTRRRSFSAV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9Z307", "url": "https://www.uniprot.org/uniprotkb/Q9Z307" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q9Z307", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9Z307" } ], "site_lbl": "Ser358" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "358", "end_pos": "358" }, { "start_pos": "374", "end_pos": "374" }, { "start_pos": "376", "end_pos": "376" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "upstream", "id": "Q9Z307-1.374.374", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q9Z307-1.376.376", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9Z307-1.374.374", "start_pos": 374, "end_pos": 374, "uniprot_canonical_ac": "Q9Z307-1", "length": 419, "uniprot_id": "KCJ16_MOUSE", "protein_name": "Inward rectifier potassium channel 16", "refseq_ac": "NP_001239136", "refseq_name": "inward rectifier potassium channel 16", "gene_name": "Kcnj16", "gene_names_uniprotkb": "Kcnj16", "gene_names_refseq": "6430410F18Rik; Kcnj16; Kir5.1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9Z307", "url": "https://www.uniprot.org/uniprotkb/Q9Z307" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9Z307", "url": "https://www.uniprot.org/uniprotkb/Q9Z307" }, { "database": "iPTMnet", "id": "Q9Z307", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9Z307" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q9Z307", "url": "https://www.uniprot.org/uniprotkb/Q9Z307", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9Z307", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9Z307", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LEKTSPARGSCNSDTNTRRR", "down_seq": "FSAVAVVSSCENPEETVLSP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9Z307", "url": "https://www.uniprot.org/uniprotkb/Q9Z307" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q9Z307", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9Z307" } ], "site_lbl": "Ser374" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "358", "end_pos": "358" }, { "start_pos": "374", "end_pos": "374" }, { "start_pos": "376", "end_pos": "376" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "Q9Z307-1.358.358", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q9Z307-1.376.376", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9Z307-1.376.376", "start_pos": 376, "end_pos": 376, "uniprot_canonical_ac": "Q9Z307-1", "length": 419, "uniprot_id": "KCJ16_MOUSE", "protein_name": "Inward rectifier potassium channel 16", "refseq_ac": "NP_001239136", "refseq_name": "inward rectifier potassium channel 16", "gene_name": "Kcnj16", "gene_names_uniprotkb": "Kcnj16", "gene_names_refseq": "6430410F18Rik; Kcnj16; Kir5.1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9Z307", "url": "https://www.uniprot.org/uniprotkb/Q9Z307" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9Z307", "url": "https://www.uniprot.org/uniprotkb/Q9Z307" }, { "database": "iPTMnet", "id": "Q9Z307", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9Z307" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q9Z307", "url": "https://www.uniprot.org/uniprotkb/Q9Z307", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9Z307", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9Z307", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KTSPARGSCNSDTNTRRRSF", "down_seq": "AVAVVSSCENPEETVLSPQD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9Z307", "url": "https://www.uniprot.org/uniprotkb/Q9Z307" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q9Z307", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9Z307" } ], "site_lbl": "Ser376" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "358", "end_pos": "358" }, { "start_pos": "374", "end_pos": "374" }, { "start_pos": "376", "end_pos": "376" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "Q9Z307-1.358.358", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q9Z307-1.374.374", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "A2ATD1-1.275.275", "start_pos": 275, "end_pos": 275, "uniprot_canonical_ac": "A2ATD1-1", "length": 454, "uniprot_id": "ISM1_MOUSE", "protein_name": "Isthmin-1", "refseq_ac": "", "refseq_name": "", "gene_name": "Ism1", "gene_names_uniprotkb": "Ism1; Ism", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2ATD1", "url": "https://www.uniprot.org/uniprotkb/A2ATD1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "EDTFRTAATEVSLLAGSEEF", "down_seq": "ATKLFEVDMDSCERWMSCKS", "glycosylation": [ { "glytoucan_ac": "G62765YT", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "TAATEVSLLAGSEEFNATK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn275", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "275", "end_pos": "275" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q3UE31-1.293.293", "start_pos": 293, "end_pos": 293, "uniprot_canonical_ac": "Q3UE31-1", "length": 404, "uniprot_id": "K0930_MOUSE", "protein_name": "Uncharacterized protein KIAA0930 homolog", "refseq_ac": "NP_001028445", "refseq_name": "uncharacterized protein KIAA0930 homolog isoform 2", "gene_name": "5031439G07Rik", "gene_names_uniprotkb": "5031439G07Rik", "gene_names_refseq": "5031439G07Rik; mKIAA0930", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3UE31", "url": "https://www.uniprot.org/uniprotkb/Q3UE31" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q3UE31", "url": "https://www.uniprot.org/uniprotkb/Q3UE31" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "Q3UE31", "url": "https://www.uniprot.org/uniprotkb/Q3UE31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "EDSSPASPMHERVTSFSTPP", "down_seq": "PERNNRPAFFSPSLKRKVPR", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr293", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q3UE31", "url": "https://www.uniprot.org/uniprotkb/Q3UE31" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ], "site_lbl": "Thr293" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "293", "end_pos": "293" }, { "start_pos": "343", "end_pos": "343" } ] }, { "type": "snv", "site_list": [ { "start_pos": "158", "end_pos": "158" }, { "start_pos": "194", "end_pos": "194" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "268", "end_pos": "268" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "362", "end_pos": "362" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "Q3UE31-1.276.276", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "Q3UE31-1.279.279", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q3UE31-1.290.290", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q3UE31-1.304.304", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q3UE31-1.306.306", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q3UE31-1.343.343", "start_pos": 343, "end_pos": 343, "uniprot_canonical_ac": "Q3UE31-1", "length": 404, "uniprot_id": "K0930_MOUSE", "protein_name": "Uncharacterized protein KIAA0930 homolog", "refseq_ac": "NP_001028445", "refseq_name": "uncharacterized protein KIAA0930 homolog isoform 2", "gene_name": "5031439G07Rik", "gene_names_uniprotkb": "5031439G07Rik", "gene_names_refseq": "5031439G07Rik; mKIAA0930", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3UE31", "url": "https://www.uniprot.org/uniprotkb/Q3UE31" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "HSANDSEEFFREDDSGADLH", "down_seq": "ATNLRSRSLSGTGRSLVGSW", "glycosylation": [ { "glytoucan_ac": "G31986NC", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "EDDSGADLHNATNLR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn343", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "293", "end_pos": "293" }, { "start_pos": "343", "end_pos": "343" } ] }, { "type": "snv", "site_list": [ { "start_pos": "158", "end_pos": "158" }, { "start_pos": "194", "end_pos": "194" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "268", "end_pos": "268" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "362", "end_pos": "362" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "Q3UE31-1.324.324", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q3UE31-1.358.358", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q3UE31-1.362.362", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q3UE31-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "Q3UE31-1", "length": 404, "uniprot_id": "K0930_MOUSE", "protein_name": "Uncharacterized protein KIAA0930 homolog", "refseq_ac": "NP_001028445", "refseq_name": "uncharacterized protein KIAA0930 homolog isoform 2", "gene_name": "5031439G07Rik", "gene_names_uniprotkb": "5031439G07Rik", "gene_names_refseq": "5031439G07Rik; mKIAA0930", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3UE31", "url": "https://www.uniprot.org/uniprotkb/Q3UE31" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A reference dataset of O-GlcNAc proteins in quadriceps skeletal muscle from mice.", "journal": "Glycobiology", "date": "2025-02-10", "authors": "Jaiswal Ruchi, Liu Yimin, Petriello Michael, Zhang Xiangmin, Yi Zhengping, Fehl Charlie", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q3UE31", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3UE31" } ], "reference": [ { "type": "PubMed", "id": "39927985", "url": "https://glygen.org/publication/PubMed/39927985" } ] } ], "crossref": [ { "id": "39927985", "url": "https://glygen.org/publication/PubMed/39927985", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q3UE31", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3UE31", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "39927985", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39927985" }, { "id": "Q3UE31", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3UE31" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "293", "end_pos": "293" }, { "start_pos": "343", "end_pos": "343" } ] }, { "type": "snv", "site_list": [ { "start_pos": "158", "end_pos": "158" }, { "start_pos": "194", "end_pos": "194" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "268", "end_pos": "268" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "362", "end_pos": "362" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q3UE31-1.158.158", "start_pos": 158, "end_pos": 158, "uniprot_canonical_ac": "Q3UE31-1", "length": 404, "uniprot_id": "K0930_MOUSE", "protein_name": "Uncharacterized protein KIAA0930 homolog", "refseq_ac": "NP_001028445", "refseq_name": "uncharacterized protein KIAA0930 homolog isoform 2", "gene_name": "5031439G07Rik", "gene_names_uniprotkb": "5031439G07Rik", "gene_names_refseq": "5031439G07Rik; mKIAA0930", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3UE31", "url": "https://www.uniprot.org/uniprotkb/Q3UE31" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3389395264", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389395264", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "SQQVFASPSKHPMDSKGEES", "down_seq": "MSYPNIFFMIDSFEEVFSDM", "snv": [ { "evidence": [ { "id": "rs3389395264", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389395264" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "K", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (KMS->NMS).", "chr_id": "15", "chr_pos": "84839636", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "K158", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "293", "end_pos": "293" }, { "start_pos": "343", "end_pos": "343" } ] }, { "type": "snv", "site_list": [ { "start_pos": "158", "end_pos": "158" }, { "start_pos": "194", "end_pos": "194" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "268", "end_pos": "268" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "362", "end_pos": "362" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q3UE31-1.194.194", "start_pos": 194, "end_pos": 194, "uniprot_canonical_ac": "Q3UE31-1", "length": 404, "uniprot_id": "K0930_MOUSE", "protein_name": "Uncharacterized protein KIAA0930 homolog", "refseq_ac": "NP_001028445", "refseq_name": "uncharacterized protein KIAA0930 homolog isoform 2", "gene_name": "5031439G07Rik", "gene_names_uniprotkb": "5031439G07Rik", "gene_names_refseq": "5031439G07Rik; mKIAA0930", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3UE31", "url": "https://www.uniprot.org/uniprotkb/Q3UE31" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3389349049", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389349049", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "VFSDMTVGEGEMVCVELVAS", "down_seq": "KTNTFQGVIFQGSIRYEALK", "snv": [ { "evidence": [ { "id": "rs3389349049", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389349049" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "D", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (DKT->NKT).", "chr_id": "15", "chr_pos": "84838183", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "D194", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "293", "end_pos": "293" }, { "start_pos": "343", "end_pos": "343" } ] }, { "type": "snv", "site_list": [ { "start_pos": "158", "end_pos": "158" }, { "start_pos": "194", "end_pos": "194" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "268", "end_pos": "268" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "362", "end_pos": "362" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q3UE31-1.268.268", "start_pos": 268, "end_pos": 268, "uniprot_canonical_ac": "Q3UE31-1", "length": 404, "uniprot_id": "K0930_MOUSE", "protein_name": "Uncharacterized protein KIAA0930 homolog", "refseq_ac": "NP_001028445", "refseq_name": "uncharacterized protein KIAA0930 homolog isoform 2", "gene_name": "5031439G07Rik", "gene_names_uniprotkb": "5031439G07Rik", "gene_names_refseq": "5031439G07Rik; mKIAA0930", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3UE31", "url": "https://www.uniprot.org/uniprotkb/Q3UE31" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q3UE31", "url": "https://www.uniprot.org/uniprotkb/Q3UE31", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GPQGKGHAEMAVSRVSTGDT", "down_seq": "PCGTEDSSPASPMHERVTSF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3UE31", "url": "https://www.uniprot.org/uniprotkb/Q3UE31" } ], "site_lbl": "Ser268" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "293", "end_pos": "293" }, { "start_pos": "343", "end_pos": "343" } ] }, { "type": "snv", "site_list": [ { "start_pos": "158", "end_pos": "158" }, { "start_pos": "194", "end_pos": "194" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "268", "end_pos": "268" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "362", "end_pos": "362" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "upstream", "id": "Q3UE31-1.276.276", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q3UE31-1.279.279", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q3UE31-1.276.276", "start_pos": 276, "end_pos": 276, "uniprot_canonical_ac": "Q3UE31-1", "length": 404, "uniprot_id": "K0930_MOUSE", "protein_name": "Uncharacterized protein KIAA0930 homolog", "refseq_ac": "NP_001028445", "refseq_name": "uncharacterized protein KIAA0930 homolog isoform 2", "gene_name": "5031439G07Rik", "gene_names_uniprotkb": "5031439G07Rik", "gene_names_refseq": "5031439G07Rik; mKIAA0930", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3UE31", "url": "https://www.uniprot.org/uniprotkb/Q3UE31" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q3UE31", "url": "https://www.uniprot.org/uniprotkb/Q3UE31" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q3UE31", "url": "https://www.uniprot.org/uniprotkb/Q3UE31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EMAVSRVSTGDTSPCGTEDS", "down_seq": "PASPMHERVTSFSTPPTPER", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3UE31", "url": "https://www.uniprot.org/uniprotkb/Q3UE31" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ], "site_lbl": "Ser276" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "293", "end_pos": "293" }, { "start_pos": "343", "end_pos": "343" } ] }, { "type": "snv", "site_list": [ { "start_pos": "158", "end_pos": "158" }, { "start_pos": "194", "end_pos": "194" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "268", "end_pos": "268" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "362", "end_pos": "362" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "Q3UE31-1.268.268", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q3UE31-1.279.279", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q3UE31-1.290.290", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "Q3UE31-1.293.293", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q3UE31-1.279.279", "start_pos": 279, "end_pos": 279, "uniprot_canonical_ac": "Q3UE31-1", "length": 404, "uniprot_id": "K0930_MOUSE", "protein_name": "Uncharacterized protein KIAA0930 homolog", "refseq_ac": "NP_001028445", "refseq_name": "uncharacterized protein KIAA0930 homolog isoform 2", "gene_name": "5031439G07Rik", "gene_names_uniprotkb": "5031439G07Rik", "gene_names_refseq": "5031439G07Rik; mKIAA0930", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3UE31", "url": "https://www.uniprot.org/uniprotkb/Q3UE31" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q3UE31", "url": "https://www.uniprot.org/uniprotkb/Q3UE31" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q3UE31", "url": "https://www.uniprot.org/uniprotkb/Q3UE31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VSRVSTGDTSPCGTEDSSPA", "down_seq": "PMHERVTSFSTPPTPERNNR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3UE31", "url": "https://www.uniprot.org/uniprotkb/Q3UE31" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ], "site_lbl": "Ser279" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "293", "end_pos": "293" }, { "start_pos": "343", "end_pos": "343" } ] }, { "type": "snv", "site_list": [ { "start_pos": "158", "end_pos": "158" }, { "start_pos": "194", "end_pos": "194" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "268", "end_pos": "268" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "362", "end_pos": "362" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "Q3UE31-1.268.268", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q3UE31-1.276.276", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q3UE31-1.290.290", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q3UE31-1.293.293", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q3UE31-1.290.290", "start_pos": 290, "end_pos": 290, "uniprot_canonical_ac": "Q3UE31-1", "length": 404, "uniprot_id": "K0930_MOUSE", "protein_name": "Uncharacterized protein KIAA0930 homolog", "refseq_ac": "NP_001028445", "refseq_name": "uncharacterized protein KIAA0930 homolog isoform 2", "gene_name": "5031439G07Rik", "gene_names_uniprotkb": "5031439G07Rik", "gene_names_refseq": "5031439G07Rik; mKIAA0930", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3UE31", "url": "https://www.uniprot.org/uniprotkb/Q3UE31" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q3UE31", "url": "https://www.uniprot.org/uniprotkb/Q3UE31" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q3UE31", "url": "https://www.uniprot.org/uniprotkb/Q3UE31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "CGTEDSSPASPMHERVTSFS", "down_seq": "PPTPERNNRPAFFSPSLKRK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q3UE31", "url": "https://www.uniprot.org/uniprotkb/Q3UE31" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ], "site_lbl": "Thr290" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "293", "end_pos": "293" }, { "start_pos": "343", "end_pos": "343" } ] }, { "type": "snv", "site_list": [ { "start_pos": "158", "end_pos": "158" }, { "start_pos": "194", "end_pos": "194" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "268", "end_pos": "268" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "362", "end_pos": "362" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "Q3UE31-1.276.276", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "Q3UE31-1.279.279", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q3UE31-1.293.293", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q3UE31-1.304.304", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q3UE31-1.306.306", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q3UE31-1.304.304", "start_pos": 304, "end_pos": 304, "uniprot_canonical_ac": "Q3UE31-1", "length": 404, "uniprot_id": "K0930_MOUSE", "protein_name": "Uncharacterized protein KIAA0930 homolog", "refseq_ac": "NP_001028445", "refseq_name": "uncharacterized protein KIAA0930 homolog isoform 2", "gene_name": "5031439G07Rik", "gene_names_uniprotkb": "5031439G07Rik", "gene_names_refseq": "5031439G07Rik; mKIAA0930", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3UE31", "url": "https://www.uniprot.org/uniprotkb/Q3UE31" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q3UE31", "url": "https://www.uniprot.org/uniprotkb/Q3UE31", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RVTSFSTPPTPERNNRPAFF", "down_seq": "PSLKRKVPRNRIAEMKKSHS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3UE31", "url": "https://www.uniprot.org/uniprotkb/Q3UE31" } ], "site_lbl": "Ser304" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "293", "end_pos": "293" }, { "start_pos": "343", "end_pos": "343" } ] }, { "type": "snv", "site_list": [ { "start_pos": "158", "end_pos": "158" }, { "start_pos": "194", "end_pos": "194" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "268", "end_pos": "268" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "362", "end_pos": "362" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "Q3UE31-1.290.290", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "Q3UE31-1.293.293", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q3UE31-1.306.306", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "Q3UE31-1.324.324", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q3UE31-1.306.306", "start_pos": 306, "end_pos": 306, "uniprot_canonical_ac": "Q3UE31-1", "length": 404, "uniprot_id": "K0930_MOUSE", "protein_name": "Uncharacterized protein KIAA0930 homolog", "refseq_ac": "NP_001028445", "refseq_name": "uncharacterized protein KIAA0930 homolog isoform 2", "gene_name": "5031439G07Rik", "gene_names_uniprotkb": "5031439G07Rik", "gene_names_refseq": "5031439G07Rik; mKIAA0930", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3UE31", "url": "https://www.uniprot.org/uniprotkb/Q3UE31" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q3UE31", "url": "https://www.uniprot.org/uniprotkb/Q3UE31", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TSFSTPPTPERNNRPAFFSP", "down_seq": "LKRKVPRNRIAEMKKSHSAN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3UE31", "url": "https://www.uniprot.org/uniprotkb/Q3UE31" } ], "site_lbl": "Ser306" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "293", "end_pos": "293" }, { "start_pos": "343", "end_pos": "343" } ] }, { "type": "snv", "site_list": [ { "start_pos": "158", "end_pos": "158" }, { "start_pos": "194", "end_pos": "194" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "268", "end_pos": "268" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "362", "end_pos": "362" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "Q3UE31-1.290.290", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "Q3UE31-1.293.293", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q3UE31-1.304.304", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q3UE31-1.324.324", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q3UE31-1.324.324", "start_pos": 324, "end_pos": 324, "uniprot_canonical_ac": "Q3UE31-1", "length": 404, "uniprot_id": "K0930_MOUSE", "protein_name": "Uncharacterized protein KIAA0930 homolog", "refseq_ac": "NP_001028445", "refseq_name": "uncharacterized protein KIAA0930 homolog isoform 2", "gene_name": "5031439G07Rik", "gene_names_uniprotkb": "5031439G07Rik", "gene_names_refseq": "5031439G07Rik; mKIAA0930", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3UE31", "url": "https://www.uniprot.org/uniprotkb/Q3UE31" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q3UE31", "url": "https://www.uniprot.org/uniprotkb/Q3UE31" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q3UE31", "url": "https://www.uniprot.org/uniprotkb/Q3UE31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SPSLKRKVPRNRIAEMKKSH", "down_seq": "ANDSEEFFREDDSGADLHNA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3UE31", "url": "https://www.uniprot.org/uniprotkb/Q3UE31" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ], "site_lbl": "Ser324" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "293", "end_pos": "293" }, { "start_pos": "343", "end_pos": "343" } ] }, { "type": "snv", "site_list": [ { "start_pos": "158", "end_pos": "158" }, { "start_pos": "194", "end_pos": "194" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "268", "end_pos": "268" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "362", "end_pos": "362" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "Q3UE31-1.304.304", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "downstream", "id": "Q3UE31-1.306.306", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q3UE31-1.343.343", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q3UE31-1.358.358", "start_pos": 358, "end_pos": 358, "uniprot_canonical_ac": "Q3UE31-1", "length": 404, "uniprot_id": "K0930_MOUSE", "protein_name": "Uncharacterized protein KIAA0930 homolog", "refseq_ac": "NP_001028445", "refseq_name": "uncharacterized protein KIAA0930 homolog isoform 2", "gene_name": "5031439G07Rik", "gene_names_uniprotkb": "5031439G07Rik", "gene_names_refseq": "5031439G07Rik; mKIAA0930", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3UE31", "url": "https://www.uniprot.org/uniprotkb/Q3UE31" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q3UE31", "url": "https://www.uniprot.org/uniprotkb/Q3UE31", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GADLHNATNLRSRSLSGTGR", "down_seq": "LVGSWLKLNRADGNFLLYAH", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3UE31", "url": "https://www.uniprot.org/uniprotkb/Q3UE31" } ], "site_lbl": "Ser358" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "293", "end_pos": "293" }, { "start_pos": "343", "end_pos": "343" } ] }, { "type": "snv", "site_list": [ { "start_pos": "158", "end_pos": "158" }, { "start_pos": "194", "end_pos": "194" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "268", "end_pos": "268" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "362", "end_pos": "362" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "Q3UE31-1.343.343", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q3UE31-1.362.362", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q3UE31-1.362.362", "start_pos": 362, "end_pos": 362, "uniprot_canonical_ac": "Q3UE31-1", "length": 404, "uniprot_id": "K0930_MOUSE", "protein_name": "Uncharacterized protein KIAA0930 homolog", "refseq_ac": "NP_001028445", "refseq_name": "uncharacterized protein KIAA0930 homolog isoform 2", "gene_name": "5031439G07Rik", "gene_names_uniprotkb": "5031439G07Rik", "gene_names_refseq": "5031439G07Rik; mKIAA0930", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3UE31", "url": "https://www.uniprot.org/uniprotkb/Q3UE31" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q3UE31", "url": "https://www.uniprot.org/uniprotkb/Q3UE31", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "HNATNLRSRSLSGTGRSLVG", "down_seq": "WLKLNRADGNFLLYAHLTYV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3UE31", "url": "https://www.uniprot.org/uniprotkb/Q3UE31" } ], "site_lbl": "Ser362" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "293", "end_pos": "293" }, { "start_pos": "343", "end_pos": "343" } ] }, { "type": "snv", "site_list": [ { "start_pos": "158", "end_pos": "158" }, { "start_pos": "194", "end_pos": "194" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "268", "end_pos": "268" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "362", "end_pos": "362" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "Q3UE31-1.343.343", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q3UE31-1.358.358", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q5SYL3-1.1482.1482", "start_pos": 1482, "end_pos": 1482, "uniprot_canonical_ac": "Q5SYL3-1", "length": 2234, "uniprot_id": "BLTP2_MOUSE", "protein_name": "Bridge-like lipid transfer protein family member 2", "refseq_ac": "NP_001002004", "refseq_name": "bridge-like lipid transfer protein family member 2 precursor", "gene_name": "Bltp2", "gene_names_uniprotkb": "Bltp2; 2610507B11Rik; Kiaa0100", "gene_names_refseq": "2610507B11Rik; Bltp2; D11Bhm178e; D11Bhm179e; E1; mKIAA0100", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q5SYL3", "url": "https://www.uniprot.org/uniprotkb/Q5SYL3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "NRDIAFGLYDGYKKAAVLKR", "down_seq": "LSTEALKGLKIDPQMSAKKP", "glycosylation": [ { "glytoucan_ac": "G80920RR", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "NLSTEALK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1482", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1482", "end_pos": "1482" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "2112", "end_pos": "2112" }, { "start_pos": "54", "end_pos": "54" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1762", "end_pos": "1762" }, { "start_pos": "447", "end_pos": "447" }, { "start_pos": "476", "end_pos": "476" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1846", "end_pos": "1846" }, { "start_pos": "2090", "end_pos": "2090" }, { "start_pos": "563", "end_pos": "563" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q5SYL3-1.178.178", "start_pos": 178, "end_pos": 178, "uniprot_canonical_ac": "Q5SYL3-1", "length": 2234, "uniprot_id": "BLTP2_MOUSE", "protein_name": "Bridge-like lipid transfer protein family member 2", "refseq_ac": "NP_001002004", "refseq_name": "bridge-like lipid transfer protein family member 2 precursor", "gene_name": "Bltp2", "gene_names_uniprotkb": "Bltp2; 2610507B11Rik; Kiaa0100", "gene_names_refseq": "2610507B11Rik; Bltp2; D11Bhm178e; D11Bhm179e; E1; mKIAA0100", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q5SYL3", "url": "https://www.uniprot.org/uniprotkb/Q5SYL3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "QISRSRFLLDSDGKSLICKV", "down_seq": "LSKINSKVLKSGQLEDTCLV", "glycosylation": [ { "glytoucan_ac": "G62765YT", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "VNLSKINSK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn178", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1482", "end_pos": "1482" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "2112", "end_pos": "2112" }, { "start_pos": "54", "end_pos": "54" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1762", "end_pos": "1762" }, { "start_pos": "447", "end_pos": "447" }, { "start_pos": "476", "end_pos": "476" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1846", "end_pos": "1846" }, { "start_pos": "2090", "end_pos": "2090" }, { "start_pos": "563", "end_pos": "563" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q5SYL3-1.2112.2112", "start_pos": 2112, "end_pos": 2112, "uniprot_canonical_ac": "Q5SYL3-1", "length": 2234, "uniprot_id": "BLTP2_MOUSE", "protein_name": "Bridge-like lipid transfer protein family member 2", "refseq_ac": "NP_001002004", "refseq_name": "bridge-like lipid transfer protein family member 2 precursor", "gene_name": "Bltp2", "gene_names_uniprotkb": "Bltp2; 2610507B11Rik; Kiaa0100", "gene_names_refseq": "2610507B11Rik; Bltp2; D11Bhm178e; D11Bhm179e; E1; mKIAA0100", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q5SYL3", "url": "https://www.uniprot.org/uniprotkb/Q5SYL3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "RKLPEHPVDDIDKMKERAAM", "down_seq": "NSFIYIKIPQVPLCVSYKGE", "glycosylation": [ { "glytoucan_ac": "G23719VF", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "MKERAAMNNSFIYIK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn2112", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1482", "end_pos": "1482" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "2112", "end_pos": "2112" }, { "start_pos": "54", "end_pos": "54" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1762", "end_pos": "1762" }, { "start_pos": "447", "end_pos": "447" }, { "start_pos": "476", "end_pos": "476" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1846", "end_pos": "1846" }, { "start_pos": "2090", "end_pos": "2090" }, { "start_pos": "563", "end_pos": "563" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q5SYL3-1.54.54", "start_pos": 54, "end_pos": 54, "uniprot_canonical_ac": "Q5SYL3-1", "length": 2234, "uniprot_id": "BLTP2_MOUSE", "protein_name": "Bridge-like lipid transfer protein family member 2", "refseq_ac": "NP_001002004", "refseq_name": "bridge-like lipid transfer protein family member 2 precursor", "gene_name": "Bltp2", "gene_names_uniprotkb": "Bltp2; 2610507B11Rik; Kiaa0100", "gene_names_refseq": "2610507B11Rik; Bltp2; D11Bhm178e; D11Bhm179e; E1; mKIAA0100", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q5SYL3", "url": "https://www.uniprot.org/uniprotkb/Q5SYL3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "CQRKLQAELKIGSFRFFWIQ", "down_seq": "VSLKFQQHQQTVEIDNLWIS", "glycosylation": [ { "glytoucan_ac": "G02815KT", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "IGSFRFFWIQNVSLK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn54", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1482", "end_pos": "1482" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "2112", "end_pos": "2112" }, { "start_pos": "54", "end_pos": "54" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1762", "end_pos": "1762" }, { "start_pos": "447", "end_pos": "447" }, { "start_pos": "476", "end_pos": "476" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1846", "end_pos": "1846" }, { "start_pos": "2090", "end_pos": "2090" }, { "start_pos": "563", "end_pos": "563" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q5SYL3-1.1762.1762", "start_pos": 1762, "end_pos": 1762, "uniprot_canonical_ac": "Q5SYL3-1", "length": 2234, "uniprot_id": "BLTP2_MOUSE", "protein_name": "Bridge-like lipid transfer protein family member 2", "refseq_ac": "NP_001002004", "refseq_name": "bridge-like lipid transfer protein family member 2 precursor", "gene_name": "Bltp2", "gene_names_uniprotkb": "Bltp2; 2610507B11Rik; Kiaa0100", "gene_names_refseq": "2610507B11Rik; Bltp2; D11Bhm178e; D11Bhm179e; E1; mKIAA0100", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q5SYL3", "url": "https://www.uniprot.org/uniprotkb/Q5SYL3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3389186589", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389186589", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "I", "start_aa": "I", "up_seq": "LLKKQEGAVDTFTLIHHELE", "down_seq": "STNPAQYAMILDIVNNLLLH", "snv": [ { "evidence": [ { "id": "rs3389186589", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389186589" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "I", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (IST->NST).", "chr_id": "11", "chr_pos": "78175607", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "I1762", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1482", "end_pos": "1482" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "2112", "end_pos": "2112" }, { "start_pos": "54", "end_pos": "54" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1762", "end_pos": "1762" }, { "start_pos": "447", "end_pos": "447" }, { "start_pos": "476", "end_pos": "476" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1846", "end_pos": "1846" }, { "start_pos": "2090", "end_pos": "2090" }, { "start_pos": "563", "end_pos": "563" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q5SYL3-1.447.447", "start_pos": 447, "end_pos": 447, "uniprot_canonical_ac": "Q5SYL3-1", "length": 2234, "uniprot_id": "BLTP2_MOUSE", "protein_name": "Bridge-like lipid transfer protein family member 2", "refseq_ac": "NP_001002004", "refseq_name": "bridge-like lipid transfer protein family member 2 precursor", "gene_name": "Bltp2", "gene_names_uniprotkb": "Bltp2; 2610507B11Rik; Kiaa0100", "gene_names_refseq": "2610507B11Rik; Bltp2; D11Bhm178e; D11Bhm179e; E1; mKIAA0100", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q5SYL3", "url": "https://www.uniprot.org/uniprotkb/Q5SYL3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3389183140", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389183140", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "I", "start_aa": "I", "up_seq": "NVSISIQLGDTPPFALGFNS", "down_seq": "SLDYQHLRPQSIHQRAVLTV", "snv": [ { "evidence": [ { "id": "rs3389183140", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389183140" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "I", "sequence_mut": "T", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (NSI->NST).", "chr_id": "11", "chr_pos": "78159035", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "I447", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1482", "end_pos": "1482" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "2112", "end_pos": "2112" }, { "start_pos": "54", "end_pos": "54" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1762", "end_pos": "1762" }, { "start_pos": "447", "end_pos": "447" }, { "start_pos": "476", "end_pos": "476" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1846", "end_pos": "1846" }, { "start_pos": "2090", "end_pos": "2090" }, { "start_pos": "563", "end_pos": "563" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q5SYL3-1.476.476", "start_pos": 476, "end_pos": 476, "uniprot_canonical_ac": "Q5SYL3-1", "length": 2234, "uniprot_id": "BLTP2_MOUSE", "protein_name": "Bridge-like lipid transfer protein family member 2", "refseq_ac": "NP_001002004", "refseq_name": "bridge-like lipid transfer protein family member 2 precursor", "gene_name": "Bltp2", "gene_names_uniprotkb": "Bltp2; 2610507B11Rik; Kiaa0100", "gene_names_refseq": "2610507B11Rik; Bltp2; D11Bhm178e; D11Bhm179e; E1; mKIAA0100", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q5SYL3", "url": "https://www.uniprot.org/uniprotkb/Q5SYL3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs235726856", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs235726856", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PQSIHQRAVLTVDHLCWRVG", "down_seq": "DSHIQRAPHPPNMHVWGEAL", "snv": [ { "evidence": [ { "id": "rs235726856", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs235726856" } ], "glycoeffect": [ "n-glyco-sequon-gain", "o-glyco-site-loss" ], "sequence_org": "S", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (SDS->NDS).", "chr_id": "11", "chr_pos": "78159230", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S476", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1482", "end_pos": "1482" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "2112", "end_pos": "2112" }, { "start_pos": "54", "end_pos": "54" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1762", "end_pos": "1762" }, { "start_pos": "447", "end_pos": "447" }, { "start_pos": "476", "end_pos": "476" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1846", "end_pos": "1846" }, { "start_pos": "2090", "end_pos": "2090" }, { "start_pos": "563", "end_pos": "563" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q5SYL3-1.1846.1846", "start_pos": 1846, "end_pos": 1846, "uniprot_canonical_ac": "Q5SYL3-1", "length": 2234, "uniprot_id": "BLTP2_MOUSE", "protein_name": "Bridge-like lipid transfer protein family member 2", "refseq_ac": "NP_001002004", "refseq_name": "bridge-like lipid transfer protein family member 2 precursor", "gene_name": "Bltp2", "gene_names_uniprotkb": "Bltp2; 2610507B11Rik; Kiaa0100", "gene_names_refseq": "2610507B11Rik; Bltp2; D11Bhm178e; D11Bhm179e; E1; mKIAA0100", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q5SYL3", "url": "https://www.uniprot.org/uniprotkb/Q5SYL3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q5SYL3", "url": "https://www.uniprot.org/uniprotkb/Q5SYL3", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AQIRHLEKQMYSIMKSLQDD", "down_seq": "KNENLLDLNQKLQLQLNQEK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q5SYL3", "url": "https://www.uniprot.org/uniprotkb/Q5SYL3" } ], "site_lbl": "Ser1846" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1482", "end_pos": "1482" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "2112", "end_pos": "2112" }, { "start_pos": "54", "end_pos": "54" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1762", "end_pos": "1762" }, { "start_pos": "447", "end_pos": "447" }, { "start_pos": "476", "end_pos": "476" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1846", "end_pos": "1846" }, { "start_pos": "2090", "end_pos": "2090" }, { "start_pos": "563", "end_pos": "563" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q5SYL3-1.2090.2090", "start_pos": 2090, "end_pos": 2090, "uniprot_canonical_ac": "Q5SYL3-1", "length": 2234, "uniprot_id": "BLTP2_MOUSE", "protein_name": "Bridge-like lipid transfer protein family member 2", "refseq_ac": "NP_001002004", "refseq_name": "bridge-like lipid transfer protein family member 2 precursor", "gene_name": "Bltp2", "gene_names_uniprotkb": "Bltp2; 2610507B11Rik; Kiaa0100", "gene_names_refseq": "2610507B11Rik; Bltp2; D11Bhm178e; D11Bhm179e; E1; mKIAA0100", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q5SYL3", "url": "https://www.uniprot.org/uniprotkb/Q5SYL3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q5SYL3", "url": "https://www.uniprot.org/uniprotkb/Q5SYL3", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PLGSGKGVAQGLTRSSGVRR", "down_seq": "FRKLPEHPVDDIDKMKERAA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q5SYL3", "url": "https://www.uniprot.org/uniprotkb/Q5SYL3" } ], "site_lbl": "Ser2090" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1482", "end_pos": "1482" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "2112", "end_pos": "2112" }, { "start_pos": "54", "end_pos": "54" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1762", "end_pos": "1762" }, { "start_pos": "447", "end_pos": "447" }, { "start_pos": "476", "end_pos": "476" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1846", "end_pos": "1846" }, { "start_pos": "2090", "end_pos": "2090" }, { "start_pos": "563", "end_pos": "563" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q5SYL3-1.563.563", "start_pos": 563, "end_pos": 563, "uniprot_canonical_ac": "Q5SYL3-1", "length": 2234, "uniprot_id": "BLTP2_MOUSE", "protein_name": "Bridge-like lipid transfer protein family member 2", "refseq_ac": "NP_001002004", "refseq_name": "bridge-like lipid transfer protein family member 2 precursor", "gene_name": "Bltp2", "gene_names_uniprotkb": "Bltp2; 2610507B11Rik; Kiaa0100", "gene_names_refseq": "2610507B11Rik; Bltp2; D11Bhm178e; D11Bhm179e; E1; mKIAA0100", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q5SYL3", "url": "https://www.uniprot.org/uniprotkb/Q5SYL3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q5SYL3", "url": "https://www.uniprot.org/uniprotkb/Q5SYL3" }, { "database": "iPTMnet", "id": "Q5SYL3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5SYL3" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q5SYL3", "url": "https://www.uniprot.org/uniprotkb/Q5SYL3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q5SYL3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5SYL3", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SRVLSLVIPQSERSAVSRKS", "down_seq": "LGESVTLLWKVDLKVEDMNL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q5SYL3", "url": "https://www.uniprot.org/uniprotkb/Q5SYL3" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q5SYL3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5SYL3" } ], "site_lbl": "Ser563" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1482", "end_pos": "1482" }, { "start_pos": "178", "end_pos": "178" }, { "start_pos": "2112", "end_pos": "2112" }, { "start_pos": "54", "end_pos": "54" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1762", "end_pos": "1762" }, { "start_pos": "447", "end_pos": "447" }, { "start_pos": "476", "end_pos": "476" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1846", "end_pos": "1846" }, { "start_pos": "2090", "end_pos": "2090" }, { "start_pos": "563", "end_pos": "563" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P09036-1.42.42", "start_pos": 42, "end_pos": 42, "uniprot_canonical_ac": "P09036-1", "length": 80, "uniprot_id": "ISK1_MOUSE", "protein_name": "Serine protease inhibitor Kazal-type 1", "refseq_ac": "NP_033284", "refseq_name": "serine protease inhibitor Kazal-type 1 precursor", "gene_name": "Spink1", "gene_names_uniprotkb": "Spink1; Spink3", "gene_names_refseq": "Spink1; Spink3; p12", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P09036", "url": "https://www.uniprot.org/uniprotkb/P09036" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Distinction of sperm-binding site and reactive site for trypsin inhibition on p12 secreted from the accessory sex glands of male mice.", "journal": "Biology of reproduction", "date": "2004", "authors": "Luo CW, Lin HJ, Gopinath SC, Chen YH", "evidence": [ { "database": "UniProtKB", "id": "P09036", "url": "https://www.uniprot.org/uniprotkb/P09036" } ], "reference": [ { "type": "PubMed", "id": "14645103", "url": "https://glygen.org/publication/PubMed/14645103" } ] } ], "crossref": [ { "id": "P09036", "url": "https://www.uniprot.org/uniprotkb/P09036", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "14645103", "url": "https://glygen.org/publication/PubMed/14645103", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "FSAKVTGKEASCHDAVAGCP", "down_seq": "IYDPVCGTDGITYANECVLC", "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "L", "comment": "Abolishes trypsin inhibitor activity. No effect on sperm binding.", "evidence": [ { "database": "UniProtKB", "id": "P09036", "url": "https://www.uniprot.org/uniprotkb/P09036" }, { "database": "PubMed", "id": "14645103", "url": "https://glygen.org/publication/PubMed/14645103" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "42", "end_pos": "42" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "68", "end_pos": "68" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P09036-1.44.44", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P09036-1.45.45", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P09036-1.44.44", "start_pos": 44, "end_pos": 44, "uniprot_canonical_ac": "P09036-1", "length": 80, "uniprot_id": "ISK1_MOUSE", "protein_name": "Serine protease inhibitor Kazal-type 1", "refseq_ac": "NP_033284", "refseq_name": "serine protease inhibitor Kazal-type 1 precursor", "gene_name": "Spink1", "gene_names_uniprotkb": "Spink1; Spink3", "gene_names_refseq": "Spink1; Spink3; p12", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P09036", "url": "https://www.uniprot.org/uniprotkb/P09036" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Distinction of sperm-binding site and reactive site for trypsin inhibition on p12 secreted from the accessory sex glands of male mice.", "journal": "Biology of reproduction", "date": "2004", "authors": "Luo CW, Lin HJ, Gopinath SC, Chen YH", "evidence": [ { "database": "UniProtKB", "id": "P09036", "url": "https://www.uniprot.org/uniprotkb/P09036" } ], "reference": [ { "type": "PubMed", "id": "14645103", "url": "https://glygen.org/publication/PubMed/14645103" } ] } ], "crossref": [ { "id": "P09036", "url": "https://www.uniprot.org/uniprotkb/P09036", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "14645103", "url": "https://glygen.org/publication/PubMed/14645103", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "AKVTGKEASCHDAVAGCPRI", "down_seq": "DPVCGTDGITYANECVLCFE", "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "V", "comment": "Severely impairs sperm binding. No effect on trypsin inhibitor activity.", "evidence": [ { "database": "UniProtKB", "id": "P09036", "url": "https://www.uniprot.org/uniprotkb/P09036" }, { "database": "PubMed", "id": "14645103", "url": "https://glygen.org/publication/PubMed/14645103" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "42", "end_pos": "42" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "68", "end_pos": "68" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P09036-1.42.42", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P09036-1.45.45", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P09036-1.45.45", "start_pos": 45, "end_pos": 45, "uniprot_canonical_ac": "P09036-1", "length": 80, "uniprot_id": "ISK1_MOUSE", "protein_name": "Serine protease inhibitor Kazal-type 1", "refseq_ac": "NP_033284", "refseq_name": "serine protease inhibitor Kazal-type 1 precursor", "gene_name": "Spink1", "gene_names_uniprotkb": "Spink1; Spink3", "gene_names_refseq": "Spink1; Spink3; p12", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P09036", "url": "https://www.uniprot.org/uniprotkb/P09036" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Distinction of sperm-binding site and reactive site for trypsin inhibition on p12 secreted from the accessory sex glands of male mice.", "journal": "Biology of reproduction", "date": "2004", "authors": "Luo CW, Lin HJ, Gopinath SC, Chen YH", "evidence": [ { "database": "UniProtKB", "id": "P09036", "url": "https://www.uniprot.org/uniprotkb/P09036" } ], "reference": [ { "type": "PubMed", "id": "14645103", "url": "https://glygen.org/publication/PubMed/14645103" } ] } ], "crossref": [ { "id": "P09036", "url": "https://www.uniprot.org/uniprotkb/P09036", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "14645103", "url": "https://glygen.org/publication/PubMed/14645103", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "KVTGKEASCHDAVAGCPRIY", "down_seq": "PVCGTDGITYANECVLCFEN", "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "G", "comment": "Fails to bind sperm. No effect on trypsin inhibitor activity.", "evidence": [ { "database": "UniProtKB", "id": "P09036", "url": "https://www.uniprot.org/uniprotkb/P09036" }, { "database": "PubMed", "id": "14645103", "url": "https://glygen.org/publication/PubMed/14645103" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "42", "end_pos": "42" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "68", "end_pos": "68" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "P09036-1.42.42", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P09036-1.44.44", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P09036-1.66.66", "start_pos": 66, "end_pos": 66, "uniprot_canonical_ac": "P09036-1", "length": 80, "uniprot_id": "ISK1_MOUSE", "protein_name": "Serine protease inhibitor Kazal-type 1", "refseq_ac": "NP_033284", "refseq_name": "serine protease inhibitor Kazal-type 1 precursor", "gene_name": "Spink1", "gene_names_uniprotkb": "Spink1; Spink3", "gene_names_refseq": "Spink1; Spink3; p12", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P09036", "url": "https://www.uniprot.org/uniprotkb/P09036" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Distinction of sperm-binding site and reactive site for trypsin inhibition on p12 secreted from the accessory sex glands of male mice.", "journal": "Biology of reproduction", "date": "2004", "authors": "Luo CW, Lin HJ, Gopinath SC, Chen YH", "evidence": [ { "database": "UniProtKB", "id": "P09036", "url": "https://www.uniprot.org/uniprotkb/P09036" } ], "reference": [ { "type": "PubMed", "id": "14645103", "url": "https://glygen.org/publication/PubMed/14645103" } ] } ], "crossref": [ { "id": "P09036", "url": "https://www.uniprot.org/uniprotkb/P09036", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "14645103", "url": "https://glygen.org/publication/PubMed/14645103", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "PVCGTDGITYANECVLCFEN", "down_seq": "KRIEPVLIRKGGPC", "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "G", "comment": "No effect on trypsin inhibitor activity or sperm binding.", "evidence": [ { "database": "UniProtKB", "id": "P09036", "url": "https://www.uniprot.org/uniprotkb/P09036" }, { "database": "PubMed", "id": "14645103", "url": "https://glygen.org/publication/PubMed/14645103" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "42", "end_pos": "42" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "68", "end_pos": "68" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "P09036-1.67.67", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P09036-1.68.68", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P09036-1.67.67", "start_pos": 67, "end_pos": 67, "uniprot_canonical_ac": "P09036-1", "length": 80, "uniprot_id": "ISK1_MOUSE", "protein_name": "Serine protease inhibitor Kazal-type 1", "refseq_ac": "NP_033284", "refseq_name": "serine protease inhibitor Kazal-type 1 precursor", "gene_name": "Spink1", "gene_names_uniprotkb": "Spink1; Spink3", "gene_names_refseq": "Spink1; Spink3; p12", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P09036", "url": "https://www.uniprot.org/uniprotkb/P09036" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Distinction of sperm-binding site and reactive site for trypsin inhibition on p12 secreted from the accessory sex glands of male mice.", "journal": "Biology of reproduction", "date": "2004", "authors": "Luo CW, Lin HJ, Gopinath SC, Chen YH", "evidence": [ { "database": "UniProtKB", "id": "P09036", "url": "https://www.uniprot.org/uniprotkb/P09036" } ], "reference": [ { "type": "PubMed", "id": "14645103", "url": "https://glygen.org/publication/PubMed/14645103" } ] } ], "crossref": [ { "id": "P09036", "url": "https://www.uniprot.org/uniprotkb/P09036", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "14645103", "url": "https://glygen.org/publication/PubMed/14645103", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "VCGTDGITYANECVLCFENR", "down_seq": "RIEPVLIRKGGPC", "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "S", "comment": "No effect on trypsin inhibitor activity or sperm binding.", "evidence": [ { "database": "UniProtKB", "id": "P09036", "url": "https://www.uniprot.org/uniprotkb/P09036" }, { "database": "PubMed", "id": "14645103", "url": "https://glygen.org/publication/PubMed/14645103" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "42", "end_pos": "42" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "68", "end_pos": "68" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "P09036-1.66.66", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P09036-1.68.68", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P09036-1.68.68", "start_pos": 68, "end_pos": 68, "uniprot_canonical_ac": "P09036-1", "length": 80, "uniprot_id": "ISK1_MOUSE", "protein_name": "Serine protease inhibitor Kazal-type 1", "refseq_ac": "NP_033284", "refseq_name": "serine protease inhibitor Kazal-type 1 precursor", "gene_name": "Spink1", "gene_names_uniprotkb": "Spink1; Spink3", "gene_names_refseq": "Spink1; Spink3; p12", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P09036", "url": "https://www.uniprot.org/uniprotkb/P09036" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Distinction of sperm-binding site and reactive site for trypsin inhibition on p12 secreted from the accessory sex glands of male mice.", "journal": "Biology of reproduction", "date": "2004", "authors": "Luo CW, Lin HJ, Gopinath SC, Chen YH", "evidence": [ { "database": "UniProtKB", "id": "P09036", "url": "https://www.uniprot.org/uniprotkb/P09036" } ], "reference": [ { "type": "PubMed", "id": "14645103", "url": "https://glygen.org/publication/PubMed/14645103" } ] } ], "crossref": [ { "id": "P09036", "url": "https://www.uniprot.org/uniprotkb/P09036", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "14645103", "url": "https://glygen.org/publication/PubMed/14645103", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "CGTDGITYANECVLCFENRK", "down_seq": "IEPVLIRKGGPC", "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "T", "comment": "No effect on trypsin inhibitor activity or sperm binding.", "evidence": [ { "database": "UniProtKB", "id": "P09036", "url": "https://www.uniprot.org/uniprotkb/P09036" }, { "database": "PubMed", "id": "14645103", "url": "https://glygen.org/publication/PubMed/14645103" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "42", "end_pos": "42" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "68", "end_pos": "68" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P09036-1.66.66", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P09036-1.67.67", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P09450-1.104.104", "start_pos": 104, "end_pos": 104, "uniprot_canonical_ac": "P09450-1", "length": 344, "uniprot_id": "JUNB_MOUSE", "protein_name": "Transcription factor JunB", "refseq_ac": "NP_032442", "refseq_name": "transcription factor JunB", "gene_name": "Junb", "gene_names_uniprotkb": "Junb; Jun-b", "gene_names_refseq": "Junb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P09450", "url": "https://www.uniprot.org/uniprotkb/P09450" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "P09450", "url": "https://www.uniprot.org/uniprotkb/P09450", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "STELERLIVPNSNGVITTTP", "down_seq": "PPGQYFYPRGGGSGGGTGGG", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr104", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P09450", "url": "https://www.uniprot.org/uniprotkb/P09450" } ], "site_lbl": "Thr104" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "104", "end_pos": "104" } ] }, { "type": "snv", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "107", "end_pos": "107" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "245", "end_pos": "245" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "298", "end_pos": "298" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "63", "end_pos": "63" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "102", "end_pos": "102" }, { "start_pos": "104", "end_pos": "104" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "256", "end_pos": "256" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P09450-1.87.87", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P09450-1.100.100", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P09450-1.102.102", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P09450-1.107.107", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P09450-1.117.117", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P09450-1.100.100", "start_pos": 100, "end_pos": 100, "uniprot_canonical_ac": "P09450-1", "length": 344, "uniprot_id": "JUNB_MOUSE", "protein_name": "Transcription factor JunB", "refseq_ac": "NP_032442", "refseq_name": "transcription factor JunB", "gene_name": "Junb", "gene_names_uniprotkb": "Junb; Jun-b", "gene_names_refseq": "Junb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P09450", "url": "https://www.uniprot.org/uniprotkb/P09450" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388457169", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388457169", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "LKLASTELERLIVPNSNGVI", "down_seq": "TTPTPPGQYFYPRGGGSGGG", "snv": [ { "evidence": [ { "id": "rs3388457169", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388457169" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "T", "sequence_mut": "M", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, signaling pathways - mapk.", "chr_id": "8", "chr_pos": "85704760", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "T100", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "104", "end_pos": "104" } ] }, { "type": "snv", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "107", "end_pos": "107" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "245", "end_pos": "245" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "298", "end_pos": "298" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "63", "end_pos": "63" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "102", "end_pos": "102" }, { "start_pos": "104", "end_pos": "104" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "256", "end_pos": "256" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P09450-1.82.82", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P09450-1.87.87", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P09450-1.102.102", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P09450-1.104.104", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P09450-1.107.107", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P09450-1.117.117", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P09450-1.107.107", "start_pos": 107, "end_pos": 107, "uniprot_canonical_ac": "P09450-1", "length": 344, "uniprot_id": "JUNB_MOUSE", "protein_name": "Transcription factor JunB", "refseq_ac": "NP_032442", "refseq_name": "transcription factor JunB", "gene_name": "Junb", "gene_names_uniprotkb": "Junb; Jun-b", "gene_names_refseq": "Junb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P09450", "url": "https://www.uniprot.org/uniprotkb/P09450" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388990595", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388990595", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "G", "start_aa": "G", "up_seq": "LERLIVPNSNGVITTTPTPP", "down_seq": "QYFYPRGGGSGGGTGGGVTE", "snv": [ { "evidence": [ { "id": "rs3388990595", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388990595" } ], "glycoeffect": [], "sequence_org": "G", "sequence_mut": "E", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, signaling pathways - mapk.", "chr_id": "8", "chr_pos": "85704739", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "G107", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "104", "end_pos": "104" } ] }, { "type": "snv", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "107", "end_pos": "107" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "245", "end_pos": "245" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "298", "end_pos": "298" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "63", "end_pos": "63" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "102", "end_pos": "102" }, { "start_pos": "104", "end_pos": "104" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "256", "end_pos": "256" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P09450-1.87.87", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P09450-1.100.100", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P09450-1.102.102", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P09450-1.104.104", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P09450-1.117.117", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P09450-1.134.134", "start_pos": 134, "end_pos": 134, "uniprot_canonical_ac": "P09450-1", "length": 344, "uniprot_id": "JUNB_MOUSE", "protein_name": "Transcription factor JunB", "refseq_ac": "NP_032442", "refseq_name": "transcription factor JunB", "gene_name": "Junb", "gene_names_uniprotkb": "Junb; Jun-b", "gene_names_refseq": "Junb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P09450", "url": "https://www.uniprot.org/uniprotkb/P09450" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388972384", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388972384", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "GGGSGGGTGGGVTEEQEGFA", "down_seq": "GFVKALDDLHKMNHVTPPNV", "snv": [ { "evidence": [ { "id": "rs3388972384", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388972384" } ], "glycoeffect": [], "sequence_org": "D", "sequence_mut": "Y", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, signaling pathways - mapk.", "chr_id": "8", "chr_pos": "85704659", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "D134", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "104", "end_pos": "104" } ] }, { "type": "snv", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "107", "end_pos": "107" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "245", "end_pos": "245" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "298", "end_pos": "298" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "63", "end_pos": "63" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "102", "end_pos": "102" }, { "start_pos": "104", "end_pos": "104" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "256", "end_pos": "256" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P09450-1.117.117", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P09450-1.149.149", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P09450-1.149.149", "start_pos": 149, "end_pos": 149, "uniprot_canonical_ac": "P09450-1", "length": 344, "uniprot_id": "JUNB_MOUSE", "protein_name": "Transcription factor JunB", "refseq_ac": "NP_032442", "refseq_name": "transcription factor JunB", "gene_name": "Junb", "gene_names_uniprotkb": "Junb; Jun-b", "gene_names_refseq": "Junb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P09450", "url": "https://www.uniprot.org/uniprotkb/P09450" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388990566", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388990566", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "V", "start_aa": "V", "up_seq": "QEGFADGFVKALDDLHKMNH", "down_seq": "TPPNVSLGASGGPQAGPGGV", "snv": [ { "evidence": [ { "id": "rs3388990566", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388990566" } ], "glycoeffect": [], "sequence_org": "V", "sequence_mut": "M", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, signaling pathways - mapk.", "chr_id": "8", "chr_pos": "85704614", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "V149", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "104", "end_pos": "104" } ] }, { "type": "snv", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "107", "end_pos": "107" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "245", "end_pos": "245" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "298", "end_pos": "298" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "63", "end_pos": "63" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "102", "end_pos": "102" }, { "start_pos": "104", "end_pos": "104" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "256", "end_pos": "256" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P09450-1.134.134", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P09450-1.183.183", "start_pos": 183, "end_pos": 183, "uniprot_canonical_ac": "P09450-1", "length": 344, "uniprot_id": "JUNB_MOUSE", "protein_name": "Transcription factor JunB", "refseq_ac": "NP_032442", "refseq_name": "transcription factor JunB", "gene_name": "Junb", "gene_names_uniprotkb": "Junb; Jun-b", "gene_names_refseq": "Junb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P09450", "url": "https://www.uniprot.org/uniprotkb/P09450" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388997996", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388997996", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QAGPGGVYAGPEPPPVYTNL", "down_seq": "SYSPASAPSGGSGTAVGTGS", "snv": [ { "evidence": [ { "id": "rs3388997996", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388997996" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "S", "sequence_mut": "C", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, signaling pathways - mapk.", "chr_id": "8", "chr_pos": "85704512", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S183", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "104", "end_pos": "104" } ] }, { "type": "snv", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "107", "end_pos": "107" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "245", "end_pos": "245" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "298", "end_pos": "298" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "63", "end_pos": "63" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "102", "end_pos": "102" }, { "start_pos": "104", "end_pos": "104" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "256", "end_pos": "256" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "upstream", "id": "P09450-1.199.199", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P09450-1.199.199", "start_pos": 199, "end_pos": 199, "uniprot_canonical_ac": "P09450-1", "length": 344, "uniprot_id": "JUNB_MOUSE", "protein_name": "Transcription factor JunB", "refseq_ac": "NP_032442", "refseq_name": "transcription factor JunB", "gene_name": "Junb", "gene_names_uniprotkb": "Junb; Jun-b", "gene_names_refseq": "Junb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P09450", "url": "https://www.uniprot.org/uniprotkb/P09450" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388985256", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388985256", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "V", "start_aa": "V", "up_seq": "YTNLSSYSPASAPSGGSGTA", "down_seq": "GTGSSYPTATISYLPHAPPF", "snv": [ { "evidence": [ { "id": "rs3388985256", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388985256" } ], "glycoeffect": [], "sequence_org": "V", "sequence_mut": "F", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, signaling pathways - mapk.", "chr_id": "8", "chr_pos": "85704464", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "V199", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "104", "end_pos": "104" } ] }, { "type": "snv", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "107", "end_pos": "107" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "245", "end_pos": "245" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "298", "end_pos": "298" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "63", "end_pos": "63" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "102", "end_pos": "102" }, { "start_pos": "104", "end_pos": "104" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "256", "end_pos": "256" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P09450-1.183.183", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P09450-1.205.205", "categories": [ "snv_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P09450-1.208.208", "categories": [ "snv_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P09450-1.219.219", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P09450-1.205.205", "start_pos": 205, "end_pos": 205, "uniprot_canonical_ac": "P09450-1", "length": 344, "uniprot_id": "JUNB_MOUSE", "protein_name": "Transcription factor JunB", "refseq_ac": "NP_032442", "refseq_name": "transcription factor JunB", "gene_name": "Junb", "gene_names_uniprotkb": "Junb; Jun-b", "gene_names_refseq": "Junb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P09450", "url": "https://www.uniprot.org/uniprotkb/P09450" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3399449400", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3399449400", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "YSPASAPSGGSGTAVGTGSS", "down_seq": "PTATISYLPHAPPFAGGHPA", "snv": [ { "evidence": [ { "id": "rs3399449400", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3399449400" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "Y", "sequence_mut": "*", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, signaling pathways - mapk.", "chr_id": "8", "chr_pos": "85704444_85704445in", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "Y205", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "104", "end_pos": "104" } ] }, { "type": "snv", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "107", "end_pos": "107" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "245", "end_pos": "245" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "298", "end_pos": "298" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "63", "end_pos": "63" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "102", "end_pos": "102" }, { "start_pos": "104", "end_pos": "104" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "256", "end_pos": "256" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "P09450-1.199.199", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P09450-1.208.208", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P09450-1.219.219", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P09450-1.208.208", "start_pos": 208, "end_pos": 208, "uniprot_canonical_ac": "P09450-1", "length": 344, "uniprot_id": "JUNB_MOUSE", "protein_name": "Transcription factor JunB", "refseq_ac": "NP_032442", "refseq_name": "transcription factor JunB", "gene_name": "Junb", "gene_names_uniprotkb": "Junb; Jun-b", "gene_names_refseq": "Junb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P09450", "url": "https://www.uniprot.org/uniprotkb/P09450" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388456638", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388456638", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "A", "start_aa": "A", "up_seq": "ASAPSGGSGTAVGTGSSYPT", "down_seq": "TISYLPHAPPFAGGHPAQLG", "snv": [ { "evidence": [ { "id": "rs3388456638", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388456638" } ], "glycoeffect": [], "sequence_org": "A", "sequence_mut": "T", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, signaling pathways - mapk.", "chr_id": "8", "chr_pos": "85704437", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "A208", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "104", "end_pos": "104" } ] }, { "type": "snv", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "107", "end_pos": "107" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "245", "end_pos": "245" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "298", "end_pos": "298" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "63", "end_pos": "63" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "102", "end_pos": "102" }, { "start_pos": "104", "end_pos": "104" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "256", "end_pos": "256" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "P09450-1.199.199", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P09450-1.205.205", "categories": [ "snv_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P09450-1.219.219", "categories": [ "snv_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P09450-1.226.226", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P09450-1.219.219", "start_pos": 219, "end_pos": 219, "uniprot_canonical_ac": "P09450-1", "length": 344, "uniprot_id": "JUNB_MOUSE", "protein_name": "Transcription factor JunB", "refseq_ac": "NP_032442", "refseq_name": "transcription factor JunB", "gene_name": "Junb", "gene_names_uniprotkb": "Junb; Jun-b", "gene_names_refseq": "Junb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P09450", "url": "https://www.uniprot.org/uniprotkb/P09450" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388997166", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388997166", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "F", "start_aa": "F", "up_seq": "VGTGSSYPTATISYLPHAPP", "down_seq": "AGGHPAQLGLSRGASAFKEE", "snv": [ { "evidence": [ { "id": "rs3388997166", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388997166" } ], "glycoeffect": [], "sequence_org": "F", "sequence_mut": "S", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, signaling pathways - mapk.", "chr_id": "8", "chr_pos": "85704403", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "F219", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "104", "end_pos": "104" } ] }, { "type": "snv", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "107", "end_pos": "107" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "245", "end_pos": "245" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "298", "end_pos": "298" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "63", "end_pos": "63" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "102", "end_pos": "102" }, { "start_pos": "104", "end_pos": "104" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "256", "end_pos": "256" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P09450-1.199.199", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P09450-1.205.205", "categories": [ "snv_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P09450-1.208.208", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P09450-1.226.226", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P09450-1.226.226", "start_pos": 226, "end_pos": 226, "uniprot_canonical_ac": "P09450-1", "length": 344, "uniprot_id": "JUNB_MOUSE", "protein_name": "Transcription factor JunB", "refseq_ac": "NP_032442", "refseq_name": "transcription factor JunB", "gene_name": "Junb", "gene_names_uniprotkb": "Junb; Jun-b", "gene_names_refseq": "Junb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P09450", "url": "https://www.uniprot.org/uniprotkb/P09450" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3389000671", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389000671", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "Q", "start_aa": "Q", "up_seq": "PTATISYLPHAPPFAGGHPA", "down_seq": "LGLSRGASAFKEEPQTVPEA", "snv": [ { "evidence": [ { "id": "rs3389000671", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389000671" } ], "glycoeffect": [], "sequence_org": "Q", "sequence_mut": "H", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, signaling pathways - mapk.", "chr_id": "8", "chr_pos": "85704381", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "Q226", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "104", "end_pos": "104" } ] }, { "type": "snv", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "107", "end_pos": "107" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "245", "end_pos": "245" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "298", "end_pos": "298" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "63", "end_pos": "63" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "102", "end_pos": "102" }, { "start_pos": "104", "end_pos": "104" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "256", "end_pos": "256" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P09450-1.208.208", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P09450-1.219.219", "categories": [ "snv_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P09450-1.245.245", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P09450-1.245.245", "start_pos": 245, "end_pos": 245, "uniprot_canonical_ac": "P09450-1", "length": 344, "uniprot_id": "JUNB_MOUSE", "protein_name": "Transcription factor JunB", "refseq_ac": "NP_032442", "refseq_name": "transcription factor JunB", "gene_name": "Junb", "gene_names_uniprotkb": "Junb; Jun-b", "gene_names_refseq": "Junb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P09450", "url": "https://www.uniprot.org/uniprotkb/P09450" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3398450043", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3398450043", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "E", "start_aa": "E", "up_seq": "AQLGLSRGASAFKEEPQTVP", "down_seq": "ARSRDATPPVSPINMEDQER", "snv": [ { "evidence": [ { "id": "rs3398450043", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3398450043" } ], "glycoeffect": [], "sequence_org": "E", "sequence_mut": "V", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, signaling pathways - mapk.", "chr_id": "8", "chr_pos": "85704325", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "E245", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "104", "end_pos": "104" } ] }, { "type": "snv", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "107", "end_pos": "107" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "245", "end_pos": "245" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "298", "end_pos": "298" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "63", "end_pos": "63" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "102", "end_pos": "102" }, { "start_pos": "104", "end_pos": "104" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "256", "end_pos": "256" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P09450-1.226.226", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P09450-1.248.248", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P09450-1.252.252", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P09450-1.256.256", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P09450-1.287.287", "start_pos": 287, "end_pos": 287, "uniprot_canonical_ac": "P09450-1", "length": 344, "uniprot_id": "JUNB_MOUSE", "protein_name": "Transcription factor JunB", "refseq_ac": "NP_032442", "refseq_name": "transcription factor JunB", "gene_name": "Junb", "gene_names_uniprotkb": "Junb; Jun-b", "gene_names_refseq": "Junb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P09450", "url": "https://www.uniprot.org/uniprotkb/P09450" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388457430", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388457430", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "L", "start_aa": "L", "up_seq": "KVERKRLRNRLAATKCRKRK", "down_seq": "ERIARLEDKVKTLKAENAGL", "snv": [ { "evidence": [ { "id": "rs3388457430", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388457430" } ], "glycoeffect": [], "sequence_org": "L", "sequence_mut": "M", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, signaling pathways - mapk.", "chr_id": "8", "chr_pos": "85704200", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "L287", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "104", "end_pos": "104" } ] }, { "type": "snv", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "107", "end_pos": "107" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "245", "end_pos": "245" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "298", "end_pos": "298" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "63", "end_pos": "63" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "102", "end_pos": "102" }, { "start_pos": "104", "end_pos": "104" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "256", "end_pos": "256" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P09450-1.289.289", "categories": [ "snv_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P09450-1.298.298", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P09450-1.289.289", "start_pos": 289, "end_pos": 289, "uniprot_canonical_ac": "P09450-1", "length": 344, "uniprot_id": "JUNB_MOUSE", "protein_name": "Transcription factor JunB", "refseq_ac": "NP_032442", "refseq_name": "transcription factor JunB", "gene_name": "Junb", "gene_names_uniprotkb": "Junb; Jun-b", "gene_names_refseq": "Junb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P09450", "url": "https://www.uniprot.org/uniprotkb/P09450" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388456795", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388456795", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "ERKRLRNRLAATKCRKRKLE", "down_seq": "IARLEDKVKTLKAENAGLSS", "snv": [ { "evidence": [ { "id": "rs3388456795", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388456795" } ], "glycoeffect": [], "sequence_org": "R", "sequence_mut": "H", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, signaling pathways - mapk.", "chr_id": "8", "chr_pos": "85704193", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "R289", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "104", "end_pos": "104" } ] }, { "type": "snv", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "107", "end_pos": "107" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "245", "end_pos": "245" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "298", "end_pos": "298" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "63", "end_pos": "63" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "102", "end_pos": "102" }, { "start_pos": "104", "end_pos": "104" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "256", "end_pos": "256" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P09450-1.287.287", "categories": [ "snv_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P09450-1.298.298", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P09450-1.298.298", "start_pos": 298, "end_pos": 298, "uniprot_canonical_ac": "P09450-1", "length": 344, "uniprot_id": "JUNB_MOUSE", "protein_name": "Transcription factor JunB", "refseq_ac": "NP_032442", "refseq_name": "transcription factor JunB", "gene_name": "Junb", "gene_names_uniprotkb": "Junb; Jun-b", "gene_names_refseq": "Junb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P09450", "url": "https://www.uniprot.org/uniprotkb/P09450" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388998003", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388998003", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "AATKCRKRKLERIARLEDKV", "down_seq": "TLKAENAGLSSAAGLLREQV", "snv": [ { "evidence": [ { "id": "rs3388998003", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388998003" } ], "glycoeffect": [], "sequence_org": "K", "sequence_mut": "M", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, signaling pathways - mapk.", "chr_id": "8", "chr_pos": "85704166", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "K298", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "104", "end_pos": "104" } ] }, { "type": "snv", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "107", "end_pos": "107" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "245", "end_pos": "245" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "298", "end_pos": "298" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "63", "end_pos": "63" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "102", "end_pos": "102" }, { "start_pos": "104", "end_pos": "104" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "256", "end_pos": "256" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "P09450-1.287.287", "categories": [ "snv_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P09450-1.289.289", "categories": [ "snv_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P09450-1.313.313", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P09450-1.313.313", "start_pos": 313, "end_pos": 313, "uniprot_canonical_ac": "P09450-1", "length": 344, "uniprot_id": "JUNB_MOUSE", "protein_name": "Transcription factor JunB", "refseq_ac": "NP_032442", "refseq_name": "transcription factor JunB", "gene_name": "Junb", "gene_names_uniprotkb": "Junb; Jun-b", "gene_names_refseq": "Junb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P09450", "url": "https://www.uniprot.org/uniprotkb/P09450" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388990567", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388990567", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "L", "start_aa": "L", "up_seq": "LEDKVKTLKAENAGLSSAAG", "down_seq": "LREQVAQLKQKVMTHVSNGC", "snv": [ { "evidence": [ { "id": "rs3388990567", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388990567" } ], "glycoeffect": [], "sequence_org": "L", "sequence_mut": "I", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, signaling pathways - mapk.", "chr_id": "8", "chr_pos": "85704122", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "L313", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "104", "end_pos": "104" } ] }, { "type": "snv", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "107", "end_pos": "107" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "245", "end_pos": "245" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "298", "end_pos": "298" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "63", "end_pos": "63" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "102", "end_pos": "102" }, { "start_pos": "104", "end_pos": "104" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "256", "end_pos": "256" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P09450-1.298.298", "categories": [ "snv_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P09450-1.324.324", "categories": [ "snv_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P09450-1.332.332", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P09450-1.324.324", "start_pos": 324, "end_pos": 324, "uniprot_canonical_ac": "P09450-1", "length": 344, "uniprot_id": "JUNB_MOUSE", "protein_name": "Transcription factor JunB", "refseq_ac": "NP_032442", "refseq_name": "transcription factor JunB", "gene_name": "Junb", "gene_names_uniprotkb": "Junb; Jun-b", "gene_names_refseq": "Junb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P09450", "url": "https://www.uniprot.org/uniprotkb/P09450" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3389001330", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389001330", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "NAGLSSAAGLLREQVAQLKQ", "down_seq": "VMTHVSNGCQLLLGVKGHAF", "snv": [ { "evidence": [ { "id": "rs3389001330", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389001330" } ], "glycoeffect": [], "sequence_org": "K", "sequence_mut": "T", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, signaling pathways - mapk.", "chr_id": "8", "chr_pos": "85704088", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "K324", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "104", "end_pos": "104" } ] }, { "type": "snv", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "107", "end_pos": "107" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "245", "end_pos": "245" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "298", "end_pos": "298" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "63", "end_pos": "63" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "102", "end_pos": "102" }, { "start_pos": "104", "end_pos": "104" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "256", "end_pos": "256" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "P09450-1.313.313", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P09450-1.332.332", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P09450-1.332.332", "start_pos": 332, "end_pos": 332, "uniprot_canonical_ac": "P09450-1", "length": 344, "uniprot_id": "JUNB_MOUSE", "protein_name": "Transcription factor JunB", "refseq_ac": "NP_032442", "refseq_name": "transcription factor JunB", "gene_name": "Junb", "gene_names_uniprotkb": "Junb; Jun-b", "gene_names_refseq": "Junb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P09450", "url": "https://www.uniprot.org/uniprotkb/P09450" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388456972", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388456972", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "G", "start_aa": "G", "up_seq": "GLLREQVAQLKQKVMTHVSN", "down_seq": "CQLLLGVKGHAF", "snv": [ { "evidence": [ { "id": "rs3388456972", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388456972" } ], "glycoeffect": [], "sequence_org": "G", "sequence_mut": "D", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, signaling pathways - mapk.", "chr_id": "8", "chr_pos": "85704064", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "G332", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "104", "end_pos": "104" } ] }, { "type": "snv", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "107", "end_pos": "107" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "245", "end_pos": "245" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "298", "end_pos": "298" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "63", "end_pos": "63" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "102", "end_pos": "102" }, { "start_pos": "104", "end_pos": "104" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "256", "end_pos": "256" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P09450-1.313.313", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P09450-1.324.324", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P09450-1.40.40", "start_pos": 40, "end_pos": 40, "uniprot_canonical_ac": "P09450-1", "length": 344, "uniprot_id": "JUNB_MOUSE", "protein_name": "Transcription factor JunB", "refseq_ac": "NP_032442", "refseq_name": "transcription factor JunB", "gene_name": "Junb", "gene_names_uniprotkb": "Junb; Jun-b", "gene_names_refseq": "Junb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P09450", "url": "https://www.uniprot.org/uniprotkb/P09450" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388456570", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388456570", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "A", "start_aa": "A", "up_seq": "YGRSPGSLSLHDYKLLKPTL", "down_seq": "LNLADPYRGLKGPGARGPGP", "snv": [ { "evidence": [ { "id": "rs3388456570", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388456570" } ], "glycoeffect": [], "sequence_org": "A", "sequence_mut": "V", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, signaling pathways - mapk.", "chr_id": "8", "chr_pos": "85704940", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "A40", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "104", "end_pos": "104" } ] }, { "type": "snv", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "107", "end_pos": "107" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "245", "end_pos": "245" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "298", "end_pos": "298" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "63", "end_pos": "63" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "102", "end_pos": "102" }, { "start_pos": "104", "end_pos": "104" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "256", "end_pos": "256" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "P09450-1.44.44", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P09450-1.44.44", "start_pos": 44, "end_pos": 44, "uniprot_canonical_ac": "P09450-1", "length": 344, "uniprot_id": "JUNB_MOUSE", "protein_name": "Transcription factor JunB", "refseq_ac": "NP_032442", "refseq_name": "transcription factor JunB", "gene_name": "Junb", "gene_names_uniprotkb": "Junb; Jun-b", "gene_names_refseq": "Junb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P09450", "url": "https://www.uniprot.org/uniprotkb/P09450" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388456903", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388456903", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "A", "start_aa": "A", "up_seq": "PGSLSLHDYKLLKPTLALNL", "down_seq": "DPYRGLKGPGARGPGPEGSG", "snv": [ { "evidence": [ { "id": "rs3388456903", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388456903" } ], "glycoeffect": [], "sequence_org": "A", "sequence_mut": "V", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, signaling pathways - mapk.", "chr_id": "8", "chr_pos": "85704928", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "A44", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "104", "end_pos": "104" } ] }, { "type": "snv", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "107", "end_pos": "107" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "245", "end_pos": "245" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "298", "end_pos": "298" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "63", "end_pos": "63" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "102", "end_pos": "102" }, { "start_pos": "104", "end_pos": "104" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "256", "end_pos": "256" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "P09450-1.40.40", "categories": [ "snv_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P09450-1.63.63", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P09450-1.63.63", "start_pos": 63, "end_pos": 63, "uniprot_canonical_ac": "P09450-1", "length": 344, "uniprot_id": "JUNB_MOUSE", "protein_name": "Transcription factor JunB", "refseq_ac": "NP_032442", "refseq_name": "transcription factor JunB", "gene_name": "Junb", "gene_names_uniprotkb": "Junb; Jun-b", "gene_names_refseq": "Junb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P09450", "url": "https://www.uniprot.org/uniprotkb/P09450" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388997993", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388997993", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LADPYRGLKGPGARGPGPEG", "down_seq": "GAGSYFSGQGSDTGASLKLA", "snv": [ { "evidence": [ { "id": "rs3388997993", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388997993" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "S", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, signaling pathways - mapk.", "chr_id": "8", "chr_pos": "85704871", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S63", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "104", "end_pos": "104" } ] }, { "type": "snv", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "107", "end_pos": "107" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "245", "end_pos": "245" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "298", "end_pos": "298" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "63", "end_pos": "63" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "102", "end_pos": "102" }, { "start_pos": "104", "end_pos": "104" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "256", "end_pos": "256" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P09450-1.44.44", "categories": [ "snv_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P09450-1.82.82", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P09450-1.82.82", "start_pos": 82, "end_pos": 82, "uniprot_canonical_ac": "P09450-1", "length": 344, "uniprot_id": "JUNB_MOUSE", "protein_name": "Transcription factor JunB", "refseq_ac": "NP_032442", "refseq_name": "transcription factor JunB", "gene_name": "Junb", "gene_names_uniprotkb": "Junb; Jun-b", "gene_names_refseq": "Junb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P09450", "url": "https://www.uniprot.org/uniprotkb/P09450" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388456953", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388456953", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "L", "start_aa": "L", "up_seq": "GSGAGSYFSGQGSDTGASLK", "down_seq": "ASTELERLIVPNSNGVITTT", "snv": [ { "evidence": [ { "id": "rs3388456953", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388456953" } ], "glycoeffect": [], "sequence_org": "L", "sequence_mut": "V", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, signaling pathways - mapk.", "chr_id": "8", "chr_pos": "85704815", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "L82", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "104", "end_pos": "104" } ] }, { "type": "snv", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "107", "end_pos": "107" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "245", "end_pos": "245" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "298", "end_pos": "298" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "63", "end_pos": "63" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "102", "end_pos": "102" }, { "start_pos": "104", "end_pos": "104" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "256", "end_pos": "256" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P09450-1.63.63", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P09450-1.87.87", "categories": [ "snv_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P09450-1.100.100", "categories": [ "snv_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P09450-1.102.102", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P09450-1.87.87", "start_pos": 87, "end_pos": 87, "uniprot_canonical_ac": "P09450-1", "length": 344, "uniprot_id": "JUNB_MOUSE", "protein_name": "Transcription factor JunB", "refseq_ac": "NP_032442", "refseq_name": "transcription factor JunB", "gene_name": "Junb", "gene_names_uniprotkb": "Junb; Jun-b", "gene_names_refseq": "Junb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P09450", "url": "https://www.uniprot.org/uniprotkb/P09450" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388993842", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388993842", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "L", "start_aa": "L", "up_seq": "SYFSGQGSDTGASLKLASTE", "down_seq": "ERLIVPNSNGVITTTPTPPG", "snv": [ { "evidence": [ { "id": "rs3388993842", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388993842" } ], "glycoeffect": [], "sequence_org": "L", "sequence_mut": "P", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, signaling pathways - mapk.", "chr_id": "8", "chr_pos": "85704799", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "L87", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "104", "end_pos": "104" } ] }, { "type": "snv", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "107", "end_pos": "107" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "245", "end_pos": "245" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "298", "end_pos": "298" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "63", "end_pos": "63" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "102", "end_pos": "102" }, { "start_pos": "104", "end_pos": "104" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "256", "end_pos": "256" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "P09450-1.82.82", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P09450-1.100.100", "categories": [ "snv_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P09450-1.102.102", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P09450-1.104.104", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P09450-1.107.107", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P09450-1.102.102", "start_pos": 102, "end_pos": 102, "uniprot_canonical_ac": "P09450-1", "length": 344, "uniprot_id": "JUNB_MOUSE", "protein_name": "Transcription factor JunB", "refseq_ac": "NP_032442", "refseq_name": "transcription factor JunB", "gene_name": "Junb", "gene_names_uniprotkb": "Junb; Jun-b", "gene_names_refseq": "Junb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P09450", "url": "https://www.uniprot.org/uniprotkb/P09450" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Regulation of IL-4 expression by the transcription factor JunB during T helper cell differentiation.", "journal": "The EMBO journal", "date": "1999", "authors": "Li B, Tournier C, Davis RJ, Flavell RA", "evidence": [ { "database": "iPTMnet", "id": "P09450", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P09450" } ], "reference": [ { "type": "PubMed", "id": "9889198", "url": "https://glygen.org/publication/PubMed/9889198" } ] } ], "crossref": [ { "id": "P09450", "url": "https://www.uniprot.org/uniprotkb/P09450", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P09450", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P09450", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "9889198", "url": "https://glygen.org/publication/PubMed/9889198", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "LASTELERLIVPNSNGVITT", "down_seq": "PTPPGQYFYPRGGGSGGGTG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P09450", "url": "https://www.uniprot.org/uniprotkb/P09450" }, { "database": "iPTMnet", "id": "P09450", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P09450" }, { "database": "PubMed", "id": "9889198", "url": "https://glygen.org/publication/PubMed/9889198" } ], "site_lbl": "Thr102" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "104", "end_pos": "104" } ] }, { "type": "snv", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "107", "end_pos": "107" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "245", "end_pos": "245" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "298", "end_pos": "298" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "63", "end_pos": "63" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "102", "end_pos": "102" }, { "start_pos": "104", "end_pos": "104" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "256", "end_pos": "256" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P09450-1.82.82", "categories": [ "snv_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P09450-1.87.87", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P09450-1.100.100", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P09450-1.104.104", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P09450-1.107.107", "categories": [ "snv_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P09450-1.117.117", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P09450-1.117.117", "start_pos": 117, "end_pos": 117, "uniprot_canonical_ac": "P09450-1", "length": 344, "uniprot_id": "JUNB_MOUSE", "protein_name": "Transcription factor JunB", "refseq_ac": "NP_032442", "refseq_name": "transcription factor JunB", "gene_name": "Junb", "gene_names_uniprotkb": "Junb; Jun-b", "gene_names_refseq": "Junb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P09450", "url": "https://www.uniprot.org/uniprotkb/P09450" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P09450", "url": "https://www.uniprot.org/uniprotkb/P09450", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GVITTTPTPPGQYFYPRGGG", "down_seq": "GGGTGGGVTEEQEGFADGFV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P09450", "url": "https://www.uniprot.org/uniprotkb/P09450" } ], "site_lbl": "Ser117" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "104", "end_pos": "104" } ] }, { "type": "snv", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "107", "end_pos": "107" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "245", "end_pos": "245" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "298", "end_pos": "298" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "63", "end_pos": "63" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "102", "end_pos": "102" }, { "start_pos": "104", "end_pos": "104" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "256", "end_pos": "256" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P09450-1.100.100", "categories": [ "snv_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P09450-1.102.102", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P09450-1.104.104", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P09450-1.107.107", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P09450-1.134.134", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P09450-1.248.248", "start_pos": 248, "end_pos": 248, "uniprot_canonical_ac": "P09450-1", "length": 344, "uniprot_id": "JUNB_MOUSE", "protein_name": "Transcription factor JunB", "refseq_ac": "NP_032442", "refseq_name": "transcription factor JunB", "gene_name": "Junb", "gene_names_uniprotkb": "Junb; Jun-b", "gene_names_refseq": "Junb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P09450", "url": "https://www.uniprot.org/uniprotkb/P09450" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P09450", "url": "https://www.uniprot.org/uniprotkb/P09450" }, { "database": "iPTMnet", "id": "P09450", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P09450" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "P09450", "url": "https://www.uniprot.org/uniprotkb/P09450", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P09450", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P09450", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GLSRGASAFKEEPQTVPEAR", "down_seq": "RDATPPVSPINMEDQERIKV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P09450", "url": "https://www.uniprot.org/uniprotkb/P09450" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "P09450", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P09450" } ], "site_lbl": "Ser248" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "104", "end_pos": "104" } ] }, { "type": "snv", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "107", "end_pos": "107" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "245", "end_pos": "245" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "298", "end_pos": "298" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "63", "end_pos": "63" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "102", "end_pos": "102" }, { "start_pos": "104", "end_pos": "104" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "256", "end_pos": "256" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "P09450-1.245.245", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P09450-1.252.252", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P09450-1.256.256", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P09450-1.252.252", "start_pos": 252, "end_pos": 252, "uniprot_canonical_ac": "P09450-1", "length": 344, "uniprot_id": "JUNB_MOUSE", "protein_name": "Transcription factor JunB", "refseq_ac": "NP_032442", "refseq_name": "transcription factor JunB", "gene_name": "Junb", "gene_names_uniprotkb": "Junb; Jun-b", "gene_names_refseq": "Junb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P09450", "url": "https://www.uniprot.org/uniprotkb/P09450" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P09450", "url": "https://www.uniprot.org/uniprotkb/P09450" }, { "database": "iPTMnet", "id": "P09450", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P09450" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "P09450", "url": "https://www.uniprot.org/uniprotkb/P09450", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P09450", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P09450", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "GASAFKEEPQTVPEARSRDA", "down_seq": "PPVSPINMEDQERIKVERKR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P09450", "url": "https://www.uniprot.org/uniprotkb/P09450" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "P09450", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P09450" } ], "site_lbl": "Thr252" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "104", "end_pos": "104" } ] }, { "type": "snv", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "107", "end_pos": "107" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "245", "end_pos": "245" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "298", "end_pos": "298" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "63", "end_pos": "63" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "102", "end_pos": "102" }, { "start_pos": "104", "end_pos": "104" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "256", "end_pos": "256" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "P09450-1.245.245", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P09450-1.248.248", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P09450-1.256.256", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P09450-1.256.256", "start_pos": 256, "end_pos": 256, "uniprot_canonical_ac": "P09450-1", "length": 344, "uniprot_id": "JUNB_MOUSE", "protein_name": "Transcription factor JunB", "refseq_ac": "NP_032442", "refseq_name": "transcription factor JunB", "gene_name": "Junb", "gene_names_uniprotkb": "Junb; Jun-b", "gene_names_refseq": "Junb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P09450", "url": "https://www.uniprot.org/uniprotkb/P09450" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P09450", "url": "https://www.uniprot.org/uniprotkb/P09450" }, { "database": "iPTMnet", "id": "P09450", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P09450" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P09450", "url": "https://www.uniprot.org/uniprotkb/P09450" }, { "database": "iPTMnet", "id": "P09450", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P09450" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] } ], "crossref": [ { "id": "P09450", "url": "https://www.uniprot.org/uniprotkb/P09450", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P09450", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P09450", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "FKEEPQTVPEARSRDATPPV", "down_seq": "PINMEDQERIKVERKRLRNR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P09450", "url": "https://www.uniprot.org/uniprotkb/P09450" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" }, { "database": "iPTMnet", "id": "P09450", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P09450" } ], "site_lbl": "Ser256" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "104", "end_pos": "104" } ] }, { "type": "snv", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "107", "end_pos": "107" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "205", "end_pos": "205" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "245", "end_pos": "245" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "298", "end_pos": "298" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "63", "end_pos": "63" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "102", "end_pos": "102" }, { "start_pos": "104", "end_pos": "104" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "256", "end_pos": "256" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "P09450-1.245.245", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P09450-1.248.248", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P09450-1.252.252", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P16382-1.129.129", "start_pos": 129, "end_pos": 129, "uniprot_canonical_ac": "P16382-1", "length": 810, "uniprot_id": "IL4RA_MOUSE", "protein_name": "Interleukin-4 receptor subunit alpha", "refseq_ac": "NP_001008700", "refseq_name": "interleukin-4 receptor subunit alpha isoform 1 precursor", "gene_name": "Il4ra; Il4r", "gene_names_uniprotkb": "Il4ra; Il4r; Il4ra", "gene_names_refseq": "CD124; Il4ra; Il4r", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16382", "url": "https://www.uniprot.org/uniprotkb/P16382" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P16382", "url": "https://www.uniprot.org/uniprotkb/P16382", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "rs3388919550", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388919550", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "RQLWQGSFSPSGNVKPLAPD", "down_seq": "LTLHTNVSDEWLLTWNNLYP", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn129", "evidence": [ { "id": "P16382", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P16382#ptm_processing" } ] } ], "snv": [ { "evidence": [ { "id": "rs3388919550", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388919550" } ], "glycoeffect": [ "n-glyco-sequon-loss" ], "sequence_org": "N", "sequence_mut": "I", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-loss (NLT->ILT).", "chr_id": "7", "chr_pos": "125169135", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "N129", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "129", "end_pos": "129" }, { "start_pos": "135", "end_pos": "135" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "568", "end_pos": "568" }, { "start_pos": "72", "end_pos": "72" } ] }, { "type": "snv", "site_list": [ { "start_pos": "129", "end_pos": "129" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "74", "end_pos": "74" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "165", "end_pos": "165" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "603", "end_pos": "603" }, { "start_pos": "631", "end_pos": "631" } ] } ], "categories": [ "glycosylation_flag", "snv_flag" ], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "upstream", "id": "P16382-1.135.135", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P16382-1.135.135", "start_pos": 135, "end_pos": 135, "uniprot_canonical_ac": "P16382-1", "length": 810, "uniprot_id": "IL4RA_MOUSE", "protein_name": "Interleukin-4 receptor subunit alpha", "refseq_ac": "NP_001008700", "refseq_name": "interleukin-4 receptor subunit alpha isoform 1 precursor", "gene_name": "Il4ra; Il4r", "gene_names_uniprotkb": "Il4ra; Il4r; Il4ra", "gene_names_refseq": "CD124; Il4ra; Il4r", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16382", "url": "https://www.uniprot.org/uniprotkb/P16382" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P16382", "url": "https://www.uniprot.org/uniprotkb/P16382", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "SFSPSGNVKPLAPDNLTLHT", "down_seq": "VSDEWLLTWNNLYPSNNLLY", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn135", "evidence": [ { "id": "P16382", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P16382#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "129", "end_pos": "129" }, { "start_pos": "135", "end_pos": "135" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "568", "end_pos": "568" }, { "start_pos": "72", "end_pos": "72" } ] }, { "type": "snv", "site_list": [ { "start_pos": "129", "end_pos": "129" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "74", "end_pos": "74" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "165", "end_pos": "165" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "603", "end_pos": "603" }, { "start_pos": "631", "end_pos": "631" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "P16382-1.129.129", "categories": [ "glycosylation_flag", "snv_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P16382-1.163.163", "start_pos": 163, "end_pos": 163, "uniprot_canonical_ac": "P16382-1", "length": 810, "uniprot_id": "IL4RA_MOUSE", "protein_name": "Interleukin-4 receptor subunit alpha", "refseq_ac": "NP_001008700", "refseq_name": "interleukin-4 receptor subunit alpha isoform 1 precursor", "gene_name": "Il4ra; Il4r", "gene_names_uniprotkb": "Il4ra; Il4r; Il4ra", "gene_names_refseq": "CD124; Il4ra; Il4r", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16382", "url": "https://www.uniprot.org/uniprotkb/P16382" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "P16382", "url": "https://www.uniprot.org/uniprotkb/P16382", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "TWNNLYPSNNLLYKDLISMV", "down_seq": "ISREDNPAEFIVYNVTYKEP", "glycosylation": [ { "glytoucan_ac": "G62765YT", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "DLISMVNISR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn163", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn163", "evidence": [ { "id": "P16382", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P16382#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "129", "end_pos": "129" }, { "start_pos": "135", "end_pos": "135" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "568", "end_pos": "568" }, { "start_pos": "72", "end_pos": "72" } ] }, { "type": "snv", "site_list": [ { "start_pos": "129", "end_pos": "129" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "74", "end_pos": "74" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "165", "end_pos": "165" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "603", "end_pos": "603" }, { "start_pos": "631", "end_pos": "631" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P16382-1.165.165", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P16382-1.568.568", "start_pos": 568, "end_pos": 568, "uniprot_canonical_ac": "P16382-1", "length": 810, "uniprot_id": "IL4RA_MOUSE", "protein_name": "Interleukin-4 receptor subunit alpha", "refseq_ac": "NP_001008700", "refseq_name": "interleukin-4 receptor subunit alpha isoform 1 precursor", "gene_name": "Il4ra; Il4r", "gene_names_uniprotkb": "Il4ra; Il4r; Il4ra", "gene_names_refseq": "CD124; Il4ra; Il4r", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16382", "url": "https://www.uniprot.org/uniprotkb/P16382" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "ESWEQILHMSVLQHGAAAGS", "down_seq": "PAPAGGYQEFVQAVKQGAAQ", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr568", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "129", "end_pos": "129" }, { "start_pos": "135", "end_pos": "135" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "568", "end_pos": "568" }, { "start_pos": "72", "end_pos": "72" } ] }, { "type": "snv", "site_list": [ { "start_pos": "129", "end_pos": "129" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "74", "end_pos": "74" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "165", "end_pos": "165" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "603", "end_pos": "603" }, { "start_pos": "631", "end_pos": "631" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "upstream", "id": "P16382-1.575.575", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P16382-1.72.72", "start_pos": 72, "end_pos": 72, "uniprot_canonical_ac": "P16382-1", "length": 810, "uniprot_id": "IL4RA_MOUSE", "protein_name": "Interleukin-4 receptor subunit alpha", "refseq_ac": "NP_001008700", "refseq_name": "interleukin-4 receptor subunit alpha isoform 1 precursor", "gene_name": "Il4ra; Il4r", "gene_names_uniprotkb": "Il4ra; Il4r; Il4ra", "gene_names_refseq": "CD124; Il4ra; Il4r", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16382", "url": "https://www.uniprot.org/uniprotkb/P16382" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P16382", "url": "https://www.uniprot.org/uniprotkb/P16382", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "VDCSSQLCLHYRLMFFEFSE", "down_seq": "LTCIPRNSASTVCVCHMEMN", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn72", "evidence": [ { "id": "P16382", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P16382#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "129", "end_pos": "129" }, { "start_pos": "135", "end_pos": "135" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "568", "end_pos": "568" }, { "start_pos": "72", "end_pos": "72" } ] }, { "type": "snv", "site_list": [ { "start_pos": "129", "end_pos": "129" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "74", "end_pos": "74" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "165", "end_pos": "165" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "603", "end_pos": "603" }, { "start_pos": "631", "end_pos": "631" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P16382-1.74.74", "categories": [ "snv_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P16382-1.197.197", "start_pos": 197, "end_pos": 197, "uniprot_canonical_ac": "P16382-1", "length": 810, "uniprot_id": "IL4RA_MOUSE", "protein_name": "Interleukin-4 receptor subunit alpha", "refseq_ac": "NP_001008700", "refseq_name": "interleukin-4 receptor subunit alpha isoform 1 precursor", "gene_name": "Il4ra; Il4r", "gene_names_uniprotkb": "Il4ra; Il4r; Il4ra", "gene_names_refseq": "CD124; Il4ra; Il4r", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16382", "url": "https://www.uniprot.org/uniprotkb/P16382" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3546204277", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3546204277", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "NVTYKEPRLSFPINILMSGV", "down_seq": "YTARVRVRSQILTGTWSEWS", "snv": [ { "evidence": [ { "id": "rs3546204277", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3546204277" } ], "glycoeffect": [ "n-glyco-sequon-gain", "o-glyco-site-loss" ], "sequence_org": "Y", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (YYT->NYT).", "chr_id": "7", "chr_pos": "125170678", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "Y197", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "129", "end_pos": "129" }, { "start_pos": "135", "end_pos": "135" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "568", "end_pos": "568" }, { "start_pos": "72", "end_pos": "72" } ] }, { "type": "snv", "site_list": [ { "start_pos": "129", "end_pos": "129" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "74", "end_pos": "74" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "165", "end_pos": "165" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "603", "end_pos": "603" }, { "start_pos": "631", "end_pos": "631" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "upstream", "id": "P16382-1.210.210", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P16382-1.210.210", "start_pos": 210, "end_pos": 210, "uniprot_canonical_ac": "P16382-1", "length": 810, "uniprot_id": "IL4RA_MOUSE", "protein_name": "Interleukin-4 receptor subunit alpha", "refseq_ac": "NP_001008700", "refseq_name": "interleukin-4 receptor subunit alpha isoform 1 precursor", "gene_name": "Il4ra; Il4r", "gene_names_uniprotkb": "Il4ra; Il4r; Il4ra", "gene_names_refseq": "CD124; Il4ra; Il4r", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16382", "url": "https://www.uniprot.org/uniprotkb/P16382" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs227474143", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs227474143", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "NILMSGVYYTARVRVRSQIL", "down_seq": "GTWSEWSPSITWYNHFQLPL", "snv": [ { "evidence": [ { "id": "rs227474143", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs227474143" } ], "glycoeffect": [ "n-glyco-sequon-gain", "o-glyco-site-loss" ], "sequence_org": "T", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (TGT->NGT).", "chr_id": "7", "chr_pos": "125170718", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "T210", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "129", "end_pos": "129" }, { "start_pos": "135", "end_pos": "135" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "568", "end_pos": "568" }, { "start_pos": "72", "end_pos": "72" } ] }, { "type": "snv", "site_list": [ { "start_pos": "129", "end_pos": "129" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "74", "end_pos": "74" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "165", "end_pos": "165" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "603", "end_pos": "603" }, { "start_pos": "631", "end_pos": "631" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P16382-1.197.197", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P16382-1.74.74", "start_pos": 74, "end_pos": 74, "uniprot_canonical_ac": "P16382-1", "length": 810, "uniprot_id": "IL4RA_MOUSE", "protein_name": "Interleukin-4 receptor subunit alpha", "refseq_ac": "NP_001008700", "refseq_name": "interleukin-4 receptor subunit alpha isoform 1 precursor", "gene_name": "Il4ra; Il4r", "gene_names_uniprotkb": "Il4ra; Il4r; Il4ra", "gene_names_refseq": "CD124; Il4ra; Il4r", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16382", "url": "https://www.uniprot.org/uniprotkb/P16382" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs244442548", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs244442548", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "CSSQLCLHYRLMFFEFSENL", "down_seq": "CIPRNSASTVCVCHMEMNRP", "snv": [ { "evidence": [ { "id": "rs244442548", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs244442548" } ], "glycoeffect": [ "n-glyco-sequon-loss", "o-glyco-site-loss" ], "sequence_org": "T", "sequence_mut": "I", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-loss (NLT->NLI).", "chr_id": "7", "chr_pos": "125168203", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "T74", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "129", "end_pos": "129" }, { "start_pos": "135", "end_pos": "135" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "568", "end_pos": "568" }, { "start_pos": "72", "end_pos": "72" } ] }, { "type": "snv", "site_list": [ { "start_pos": "129", "end_pos": "129" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "74", "end_pos": "74" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "165", "end_pos": "165" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "603", "end_pos": "603" }, { "start_pos": "631", "end_pos": "631" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P16382-1.72.72", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P16382-1.165.165", "start_pos": 165, "end_pos": 165, "uniprot_canonical_ac": "P16382-1", "length": 810, "uniprot_id": "IL4RA_MOUSE", "protein_name": "Interleukin-4 receptor subunit alpha", "refseq_ac": "NP_001008700", "refseq_name": "interleukin-4 receptor subunit alpha isoform 1 precursor", "gene_name": "Il4ra; Il4r", "gene_names_uniprotkb": "Il4ra; Il4r; Il4ra", "gene_names_refseq": "CD124; Il4ra; Il4r", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16382", "url": "https://www.uniprot.org/uniprotkb/P16382" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "The phagosomal proteome in interferon-gamma-activated macrophages.", "journal": "Immunity", "date": "2009", "authors": "Trost M, English L, Lemieux S, Courcelles M, Desjardins M, Thibault P", "evidence": [ { "database": "UniProtKB", "id": "P16382", "url": "https://www.uniprot.org/uniprotkb/P16382" }, { "database": "iPTMnet", "id": "P16382", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16382" } ], "reference": [ { "type": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" } ] } ], "crossref": [ { "id": "P16382", "url": "https://www.uniprot.org/uniprotkb/P16382", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P16382", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16382", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NNLYPSNNLLYKDLISMVNI", "down_seq": "REDNPAEFIVYNVTYKEPRL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P16382", "url": "https://www.uniprot.org/uniprotkb/P16382" }, { "database": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" }, { "database": "iPTMnet", "id": "P16382", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16382" } ], "site_lbl": "Ser165" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "129", "end_pos": "129" }, { "start_pos": "135", "end_pos": "135" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "568", "end_pos": "568" }, { "start_pos": "72", "end_pos": "72" } ] }, { "type": "snv", "site_list": [ { "start_pos": "129", "end_pos": "129" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "74", "end_pos": "74" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "165", "end_pos": "165" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "603", "end_pos": "603" }, { "start_pos": "631", "end_pos": "631" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P16382-1.163.163", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P16382-1.500.500", "start_pos": 500, "end_pos": 500, "uniprot_canonical_ac": "P16382-1", "length": 810, "uniprot_id": "IL4RA_MOUSE", "protein_name": "Interleukin-4 receptor subunit alpha", "refseq_ac": "NP_001008700", "refseq_name": "interleukin-4 receptor subunit alpha isoform 1 precursor", "gene_name": "Il4ra; Il4r", "gene_names_uniprotkb": "Il4ra; Il4r; Il4ra", "gene_names_refseq": "CD124; Il4ra; Il4r", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16382", "url": "https://www.uniprot.org/uniprotkb/P16382" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P16382", "url": "https://www.uniprot.org/uniprotkb/P16382", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "QSAPTLACTQVPLVLADNPA", "down_seq": "RSFSDCCSPAPNPGELAPEQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "P16382", "url": "https://www.uniprot.org/uniprotkb/P16382" } ], "site_lbl": "Tyr500" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "129", "end_pos": "129" }, { "start_pos": "135", "end_pos": "135" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "568", "end_pos": "568" }, { "start_pos": "72", "end_pos": "72" } ] }, { "type": "snv", "site_list": [ { "start_pos": "129", "end_pos": "129" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "74", "end_pos": "74" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "165", "end_pos": "165" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "603", "end_pos": "603" }, { "start_pos": "631", "end_pos": "631" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P16382-1.575.575", "start_pos": 575, "end_pos": 575, "uniprot_canonical_ac": "P16382-1", "length": 810, "uniprot_id": "IL4RA_MOUSE", "protein_name": "Interleukin-4 receptor subunit alpha", "refseq_ac": "NP_001008700", "refseq_name": "interleukin-4 receptor subunit alpha isoform 1 precursor", "gene_name": "Il4ra; Il4r", "gene_names_uniprotkb": "Il4ra; Il4r; Il4ra", "gene_names_refseq": "CD124; Il4ra; Il4r", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16382", "url": "https://www.uniprot.org/uniprotkb/P16382" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P16382", "url": "https://www.uniprot.org/uniprotkb/P16382", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "HMSVLQHGAAAGSTPAPAGG", "down_seq": "QEFVQAVKQGAAQDPGVPGV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "P16382", "url": "https://www.uniprot.org/uniprotkb/P16382" } ], "site_lbl": "Tyr575" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "129", "end_pos": "129" }, { "start_pos": "135", "end_pos": "135" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "568", "end_pos": "568" }, { "start_pos": "72", "end_pos": "72" } ] }, { "type": "snv", "site_list": [ { "start_pos": "129", "end_pos": "129" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "74", "end_pos": "74" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "165", "end_pos": "165" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "603", "end_pos": "603" }, { "start_pos": "631", "end_pos": "631" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "P16382-1.568.568", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P16382-1.603.603", "start_pos": 603, "end_pos": 603, "uniprot_canonical_ac": "P16382-1", "length": 810, "uniprot_id": "IL4RA_MOUSE", "protein_name": "Interleukin-4 receptor subunit alpha", "refseq_ac": "NP_001008700", "refseq_name": "interleukin-4 receptor subunit alpha isoform 1 precursor", "gene_name": "Il4ra; Il4r", "gene_names_uniprotkb": "Il4ra; Il4r; Il4ra", "gene_names_refseq": "CD124; Il4ra; Il4r", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16382", "url": "https://www.uniprot.org/uniprotkb/P16382" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P16382", "url": "https://www.uniprot.org/uniprotkb/P16382", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "KQGAAQDPGVPGVRPSGDPG", "down_seq": "KAFSSLLSSNGIRGDTAAAG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "P16382", "url": "https://www.uniprot.org/uniprotkb/P16382" } ], "site_lbl": "Tyr603" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "129", "end_pos": "129" }, { "start_pos": "135", "end_pos": "135" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "568", "end_pos": "568" }, { "start_pos": "72", "end_pos": "72" } ] }, { "type": "snv", "site_list": [ { "start_pos": "129", "end_pos": "129" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "74", "end_pos": "74" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "165", "end_pos": "165" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "603", "end_pos": "603" }, { "start_pos": "631", "end_pos": "631" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P16382-1.631.631", "start_pos": 631, "end_pos": 631, "uniprot_canonical_ac": "P16382-1", "length": 810, "uniprot_id": "IL4RA_MOUSE", "protein_name": "Interleukin-4 receptor subunit alpha", "refseq_ac": "NP_001008700", "refseq_name": "interleukin-4 receptor subunit alpha isoform 1 precursor", "gene_name": "Il4ra; Il4r", "gene_names_uniprotkb": "Il4ra; Il4r; Il4ra", "gene_names_refseq": "CD124; Il4ra; Il4r", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16382", "url": "https://www.uniprot.org/uniprotkb/P16382" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P16382", "url": "https://www.uniprot.org/uniprotkb/P16382", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "SSNGIRGDTAAAGTDDGHGG", "down_seq": "KPFQNPVPNQSPSSVPLFTF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "P16382", "url": "https://www.uniprot.org/uniprotkb/P16382" } ], "site_lbl": "Tyr631" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "129", "end_pos": "129" }, { "start_pos": "135", "end_pos": "135" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "568", "end_pos": "568" }, { "start_pos": "72", "end_pos": "72" } ] }, { "type": "snv", "site_list": [ { "start_pos": "129", "end_pos": "129" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "74", "end_pos": "74" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "165", "end_pos": "165" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "575", "end_pos": "575" }, { "start_pos": "603", "end_pos": "603" }, { "start_pos": "631", "end_pos": "631" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q03717-1.442.442", "start_pos": 442, "end_pos": 442, "uniprot_canonical_ac": "Q03717-1", "length": 857, "uniprot_id": "KCNB1_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily B member 1", "refseq_ac": "NP_032446", "refseq_name": "potassium voltage-gated channel subfamily B member 1", "gene_name": "Kcnb1", "gene_names_uniprotkb": "Kcnb1", "gene_names_refseq": "Kcnb1; Kcr1-1; Kv2.1; Shab", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "EQKRQEKAIKRREALERAKR", "down_seq": "GSIVSMNMKDAFARSIEMMD", "glycosylation": [ { "glytoucan_ac": "G62765YT", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "NGSIVSMNMK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn442", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "442", "end_pos": "442" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "711", "end_pos": "711" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "457", "end_pos": "457" }, { "start_pos": "484", "end_pos": "484" }, { "start_pos": "496", "end_pos": "496" }, { "start_pos": "503", "end_pos": "503" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "541", "end_pos": "541" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "655", "end_pos": "655" }, { "start_pos": "719", "end_pos": "719" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "799", "end_pos": "799" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "836", "end_pos": "836" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "Q03717-1.444.444", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q03717-1.457.457", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03717-1.576.576", "start_pos": 576, "end_pos": 576, "uniprot_canonical_ac": "Q03717-1", "length": 857, "uniprot_id": "KCNB1_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily B member 1", "refseq_ac": "NP_032446", "refseq_name": "potassium voltage-gated channel subfamily B member 1", "gene_name": "Kcnb1", "gene_names_uniprotkb": "Kcnb1", "gene_names_refseq": "Kcnb1; Kcr1-1; Kv2.1; Shab", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q03717", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q03717" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Age-related loss of neural stem cell O-GlcNAc promotes a glial fate switch through STAT3 activation.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2020", "authors": "White CW 3rd, Fan X, Maynard JC, Wheatley EG, Bieri G, Couthouis J, Burlingame AL, Villeda SA", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q03717", "url": "https://oglcnac.org/atlas/detail/Q03717" } ], "reference": [ { "type": "PubMed", "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054" } ] } ], "crossref": [ { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q03717", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q03717", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q03717", "url": "https://oglcnac.org/atlas/detail/Q03717", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "PQEELEMGSMPSPVAPLPTR", "down_seq": "EGVIDMRSMSSIDSFISCAT", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr576", "evidence": [ { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "Q03717", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q03717" }, { "id": "32848054", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32848054" }, { "id": "Q03717", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q03717" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "442", "end_pos": "442" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "711", "end_pos": "711" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "457", "end_pos": "457" }, { "start_pos": "484", "end_pos": "484" }, { "start_pos": "496", "end_pos": "496" }, { "start_pos": "503", "end_pos": "503" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "541", "end_pos": "541" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "655", "end_pos": "655" }, { "start_pos": "719", "end_pos": "719" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "799", "end_pos": "799" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "836", "end_pos": "836" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "Q03717-1.567.567", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q03717-1.590.590", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "Q03717-1.593.593", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03717-1.711.711", "start_pos": 711, "end_pos": 711, "uniprot_canonical_ac": "Q03717-1", "length": 857, "uniprot_id": "KCNB1_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily B member 1", "refseq_ac": "NP_032446", "refseq_name": "potassium voltage-gated channel subfamily B member 1", "gene_name": "Kcnb1", "gene_names_uniprotkb": "Kcnb1", "gene_names_refseq": "Kcnb1; Kcr1-1; Kv2.1; Shab", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q03717", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q03717" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] } ], "crossref": [ { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q03717", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q03717", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "HDPLRNRGGAAAAVAGLECA", "down_seq": "LLDKPVLSPESSIYTTASAR", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser711", "evidence": [ { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "Q03717", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q03717" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "442", "end_pos": "442" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "711", "end_pos": "711" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "457", "end_pos": "457" }, { "start_pos": "484", "end_pos": "484" }, { "start_pos": "496", "end_pos": "496" }, { "start_pos": "503", "end_pos": "503" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "541", "end_pos": "541" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "655", "end_pos": "655" }, { "start_pos": "719", "end_pos": "719" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "799", "end_pos": "799" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "836", "end_pos": "836" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "upstream", "id": "Q03717-1.719.719", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03717-1.128.128", "start_pos": 128, "end_pos": 128, "uniprot_canonical_ac": "Q03717-1", "length": 857, "uniprot_id": "KCNB1_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily B member 1", "refseq_ac": "NP_032446", "refseq_name": "potassium voltage-gated channel subfamily B member 1", "gene_name": "Kcnb1", "gene_names_uniprotkb": "Kcnb1", "gene_names_refseq": "Kcnb1; Kcr1-1; Kv2.1; Shab", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "EEMCALSFSQELDYWGIDEI", "down_seq": "LESCCQARYHQKKEQMNEEL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by Src", "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" } ], "site_lbl": "Tyr128" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "442", "end_pos": "442" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "711", "end_pos": "711" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "457", "end_pos": "457" }, { "start_pos": "484", "end_pos": "484" }, { "start_pos": "496", "end_pos": "496" }, { "start_pos": "503", "end_pos": "503" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "541", "end_pos": "541" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "655", "end_pos": "655" }, { "start_pos": "719", "end_pos": "719" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "799", "end_pos": "799" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "836", "end_pos": "836" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q03717-1.15.15", "start_pos": 15, "end_pos": 15, "uniprot_canonical_ac": "Q03717-1", "length": 857, "uniprot_id": "KCNB1_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily B member 1", "refseq_ac": "NP_032446", "refseq_name": "potassium voltage-gated channel subfamily B member 1", "gene_name": "Kcnb1", "gene_names_uniprotkb": "Kcnb1", "gene_names_refseq": "Kcnb1; Kcr1-1; Kv2.1; Shab", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MPAGMTKHGSRSTS", "down_seq": "LPPEPMEIVRSKACSRRVRL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" } ], "site_lbl": "Ser15" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "442", "end_pos": "442" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "711", "end_pos": "711" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "457", "end_pos": "457" }, { "start_pos": "484", "end_pos": "484" }, { "start_pos": "496", "end_pos": "496" }, { "start_pos": "503", "end_pos": "503" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "541", "end_pos": "541" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "655", "end_pos": "655" }, { "start_pos": "719", "end_pos": "719" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "799", "end_pos": "799" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "836", "end_pos": "836" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q03717-1.444.444", "start_pos": 444, "end_pos": 444, "uniprot_canonical_ac": "Q03717-1", "length": 857, "uniprot_id": "KCNB1_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily B member 1", "refseq_ac": "NP_032446", "refseq_name": "potassium voltage-gated channel subfamily B member 1", "gene_name": "Kcnb1", "gene_names_uniprotkb": "Kcnb1", "gene_names_refseq": "Kcnb1; Kcr1-1; Kv2.1; Shab", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" }, { "database": "iPTMnet", "id": "Q03717", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03717" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q03717", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03717", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KRQEKAIKRREALERAKRNG", "down_seq": "IVSMNMKDAFARSIEMMDIV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q03717", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03717" } ], "site_lbl": "Ser444" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "442", "end_pos": "442" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "711", "end_pos": "711" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "457", "end_pos": "457" }, { "start_pos": "484", "end_pos": "484" }, { "start_pos": "496", "end_pos": "496" }, { "start_pos": "503", "end_pos": "503" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "541", "end_pos": "541" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "655", "end_pos": "655" }, { "start_pos": "719", "end_pos": "719" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "799", "end_pos": "799" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "836", "end_pos": "836" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "Q03717-1.442.442", "categories": [ "glycosylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q03717-1.457.457", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03717-1.457.457", "start_pos": 457, "end_pos": 457, "uniprot_canonical_ac": "Q03717-1", "length": 857, "uniprot_id": "KCNB1_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily B member 1", "refseq_ac": "NP_032446", "refseq_name": "potassium voltage-gated channel subfamily B member 1", "gene_name": "Kcnb1", "gene_names_uniprotkb": "Kcnb1", "gene_names_refseq": "Kcnb1; Kcr1-1; Kv2.1; Shab", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" }, { "database": "iPTMnet", "id": "Q03717", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03717" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q03717", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03717", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ERAKRNGSIVSMNMKDAFAR", "down_seq": "IEMMDIVVEKNGEGVAKKDK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q03717", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03717" } ], "site_lbl": "Ser457" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "442", "end_pos": "442" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "711", "end_pos": "711" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "457", "end_pos": "457" }, { "start_pos": "484", "end_pos": "484" }, { "start_pos": "496", "end_pos": "496" }, { "start_pos": "503", "end_pos": "503" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "541", "end_pos": "541" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "655", "end_pos": "655" }, { "start_pos": "719", "end_pos": "719" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "799", "end_pos": "799" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "836", "end_pos": "836" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "Q03717-1.442.442", "categories": [ "glycosylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "Q03717-1.444.444", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03717-1.484.484", "start_pos": 484, "end_pos": 484, "uniprot_canonical_ac": "Q03717-1", "length": 857, "uniprot_id": "KCNB1_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily B member 1", "refseq_ac": "NP_032446", "refseq_name": "potassium voltage-gated channel subfamily B member 1", "gene_name": "Kcnb1", "gene_names_uniprotkb": "Kcnb1", "gene_names_refseq": "Kcnb1; Kcr1-1; Kv2.1; Shab", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VVEKNGEGVAKKDKVQDNHL", "down_seq": "PNKWKWTKRALSETSSSKSF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" } ], "site_lbl": "Ser484" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "442", "end_pos": "442" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "711", "end_pos": "711" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "457", "end_pos": "457" }, { "start_pos": "484", "end_pos": "484" }, { "start_pos": "496", "end_pos": "496" }, { "start_pos": "503", "end_pos": "503" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "541", "end_pos": "541" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "655", "end_pos": "655" }, { "start_pos": "719", "end_pos": "719" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "799", "end_pos": "799" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "836", "end_pos": "836" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "upstream", "id": "Q03717-1.496.496", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q03717-1.503.503", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q03717-1.496.496", "start_pos": 496, "end_pos": 496, "uniprot_canonical_ac": "Q03717-1", "length": 857, "uniprot_id": "KCNB1_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily B member 1", "refseq_ac": "NP_032446", "refseq_name": "potassium voltage-gated channel subfamily B member 1", "gene_name": "Kcnb1", "gene_names_uniprotkb": "Kcnb1", "gene_names_refseq": "Kcnb1; Kcr1-1; Kv2.1; Shab", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DKVQDNHLSPNKWKWTKRAL", "down_seq": "ETSSSKSFETKEQGSPEKAR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" } ], "site_lbl": "Ser496" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "442", "end_pos": "442" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "711", "end_pos": "711" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "457", "end_pos": "457" }, { "start_pos": "484", "end_pos": "484" }, { "start_pos": "496", "end_pos": "496" }, { "start_pos": "503", "end_pos": "503" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "541", "end_pos": "541" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "655", "end_pos": "655" }, { "start_pos": "719", "end_pos": "719" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "799", "end_pos": "799" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "836", "end_pos": "836" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "Q03717-1.484.484", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q03717-1.503.503", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q03717-1.503.503", "start_pos": 503, "end_pos": 503, "uniprot_canonical_ac": "Q03717-1", "length": 857, "uniprot_id": "KCNB1_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily B member 1", "refseq_ac": "NP_032446", "refseq_name": "potassium voltage-gated channel subfamily B member 1", "gene_name": "Kcnb1", "gene_names_uniprotkb": "Kcnb1", "gene_names_refseq": "Kcnb1; Kcr1-1; Kv2.1; Shab", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LSPNKWKWTKRALSETSSSK", "down_seq": "FETKEQGSPEKARSSSSPQH", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" } ], "site_lbl": "Ser503" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "442", "end_pos": "442" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "711", "end_pos": "711" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "457", "end_pos": "457" }, { "start_pos": "484", "end_pos": "484" }, { "start_pos": "496", "end_pos": "496" }, { "start_pos": "503", "end_pos": "503" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "541", "end_pos": "541" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "655", "end_pos": "655" }, { "start_pos": "719", "end_pos": "719" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "799", "end_pos": "799" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "836", "end_pos": "836" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "Q03717-1.484.484", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "Q03717-1.496.496", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q03717-1.519.519", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "Q03717-1.520.520", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q03717-1.519.519", "start_pos": 519, "end_pos": 519, "uniprot_canonical_ac": "Q03717-1", "length": 857, "uniprot_id": "KCNB1_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily B member 1", "refseq_ac": "NP_032446", "refseq_name": "potassium voltage-gated channel subfamily B member 1", "gene_name": "Kcnb1", "gene_names_uniprotkb": "Kcnb1", "gene_names_refseq": "Kcnb1; Kcr1-1; Kv2.1; Shab", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SSSKSFETKEQGSPEKARSS", "down_seq": "SPQHLNVQQLQDMYSKMAKT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" } ], "site_lbl": "Ser519" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "442", "end_pos": "442" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "711", "end_pos": "711" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "457", "end_pos": "457" }, { "start_pos": "484", "end_pos": "484" }, { "start_pos": "496", "end_pos": "496" }, { "start_pos": "503", "end_pos": "503" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "541", "end_pos": "541" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "655", "end_pos": "655" }, { "start_pos": "719", "end_pos": "719" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "799", "end_pos": "799" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "836", "end_pos": "836" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "Q03717-1.503.503", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q03717-1.520.520", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q03717-1.520.520", "start_pos": 520, "end_pos": 520, "uniprot_canonical_ac": "Q03717-1", "length": 857, "uniprot_id": "KCNB1_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily B member 1", "refseq_ac": "NP_032446", "refseq_name": "potassium voltage-gated channel subfamily B member 1", "gene_name": "Kcnb1", "gene_names_uniprotkb": "Kcnb1", "gene_names_refseq": "Kcnb1; Kcr1-1; Kv2.1; Shab", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SSKSFETKEQGSPEKARSSS", "down_seq": "PQHLNVQQLQDMYSKMAKTQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by CDK5; in vitro", "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" } ], "site_lbl": "Ser520" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "442", "end_pos": "442" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "711", "end_pos": "711" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "457", "end_pos": "457" }, { "start_pos": "484", "end_pos": "484" }, { "start_pos": "496", "end_pos": "496" }, { "start_pos": "503", "end_pos": "503" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "541", "end_pos": "541" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "655", "end_pos": "655" }, { "start_pos": "719", "end_pos": "719" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "799", "end_pos": "799" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "836", "end_pos": "836" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "Q03717-1.503.503", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q03717-1.519.519", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q03717-1.541.541", "start_pos": 541, "end_pos": 541, "uniprot_canonical_ac": "Q03717-1", "length": 857, "uniprot_id": "KCNB1_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily B member 1", "refseq_ac": "NP_032446", "refseq_name": "potassium voltage-gated channel subfamily B member 1", "gene_name": "Kcnb1", "gene_names_uniprotkb": "Kcnb1", "gene_names_refseq": "Kcnb1; Kcr1-1; Kv2.1; Shab", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PQHLNVQQLQDMYSKMAKTQ", "down_seq": "QPILNTKEMAPQSQPQEELE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" } ], "site_lbl": "Ser541" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "442", "end_pos": "442" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "711", "end_pos": "711" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "457", "end_pos": "457" }, { "start_pos": "484", "end_pos": "484" }, { "start_pos": "496", "end_pos": "496" }, { "start_pos": "503", "end_pos": "503" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "541", "end_pos": "541" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "655", "end_pos": "655" }, { "start_pos": "719", "end_pos": "719" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "799", "end_pos": "799" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "836", "end_pos": "836" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q03717-1.567.567", "start_pos": 567, "end_pos": 567, "uniprot_canonical_ac": "Q03717-1", "length": 857, "uniprot_id": "KCNB1_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily B member 1", "refseq_ac": "NP_032446", "refseq_name": "potassium voltage-gated channel subfamily B member 1", "gene_name": "Kcnb1", "gene_names_uniprotkb": "Kcnb1", "gene_names_refseq": "Kcnb1; Kcr1-1; Kv2.1; Shab", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TKEMAPQSQPQEELEMGSMP", "down_seq": "PVAPLPTRTEGVIDMRSMSS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" } ], "site_lbl": "Ser567" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "442", "end_pos": "442" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "711", "end_pos": "711" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "457", "end_pos": "457" }, { "start_pos": "484", "end_pos": "484" }, { "start_pos": "496", "end_pos": "496" }, { "start_pos": "503", "end_pos": "503" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "541", "end_pos": "541" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "655", "end_pos": "655" }, { "start_pos": "719", "end_pos": "719" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "799", "end_pos": "799" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "836", "end_pos": "836" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "upstream", "id": "Q03717-1.576.576", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q03717-1.590.590", "start_pos": 590, "end_pos": 590, "uniprot_canonical_ac": "Q03717-1", "length": 857, "uniprot_id": "KCNB1_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily B member 1", "refseq_ac": "NP_032446", "refseq_name": "potassium voltage-gated channel subfamily B member 1", "gene_name": "Kcnb1", "gene_names_uniprotkb": "Kcnb1", "gene_names_refseq": "Kcnb1; Kcr1-1; Kv2.1; Shab", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "APLPTRTEGVIDMRSMSSID", "down_seq": "FISCATDFPEATRFSHSPLA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" } ], "site_lbl": "Ser590" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "442", "end_pos": "442" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "711", "end_pos": "711" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "457", "end_pos": "457" }, { "start_pos": "484", "end_pos": "484" }, { "start_pos": "496", "end_pos": "496" }, { "start_pos": "503", "end_pos": "503" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "541", "end_pos": "541" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "655", "end_pos": "655" }, { "start_pos": "719", "end_pos": "719" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "799", "end_pos": "799" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "836", "end_pos": "836" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "Q03717-1.576.576", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q03717-1.593.593", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "Q03717-1.607.607", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q03717-1.593.593", "start_pos": 593, "end_pos": 593, "uniprot_canonical_ac": "Q03717-1", "length": 857, "uniprot_id": "KCNB1_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily B member 1", "refseq_ac": "NP_032446", "refseq_name": "potassium voltage-gated channel subfamily B member 1", "gene_name": "Kcnb1", "gene_names_uniprotkb": "Kcnb1", "gene_names_refseq": "Kcnb1; Kcr1-1; Kv2.1; Shab", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PTRTEGVIDMRSMSSIDSFI", "down_seq": "CATDFPEATRFSHSPLASLS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" } ], "site_lbl": "Ser593" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "442", "end_pos": "442" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "711", "end_pos": "711" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "457", "end_pos": "457" }, { "start_pos": "484", "end_pos": "484" }, { "start_pos": "496", "end_pos": "496" }, { "start_pos": "503", "end_pos": "503" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "541", "end_pos": "541" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "655", "end_pos": "655" }, { "start_pos": "719", "end_pos": "719" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "799", "end_pos": "799" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "836", "end_pos": "836" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "Q03717-1.576.576", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q03717-1.590.590", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q03717-1.607.607", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q03717-1.607.607", "start_pos": 607, "end_pos": 607, "uniprot_canonical_ac": "Q03717-1", "length": 857, "uniprot_id": "KCNB1_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily B member 1", "refseq_ac": "NP_032446", "refseq_name": "potassium voltage-gated channel subfamily B member 1", "gene_name": "Kcnb1", "gene_names_uniprotkb": "Kcnb1", "gene_names_refseq": "Kcnb1; Kcr1-1; Kv2.1; Shab", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SIDSFISCATDFPEATRFSH", "down_seq": "PLASLSGKSGGSTAPEVGWR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by CDK5", "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" } ], "site_lbl": "Ser607" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "442", "end_pos": "442" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "711", "end_pos": "711" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "457", "end_pos": "457" }, { "start_pos": "484", "end_pos": "484" }, { "start_pos": "496", "end_pos": "496" }, { "start_pos": "503", "end_pos": "503" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "541", "end_pos": "541" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "655", "end_pos": "655" }, { "start_pos": "719", "end_pos": "719" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "799", "end_pos": "799" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "836", "end_pos": "836" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "Q03717-1.590.590", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "Q03717-1.593.593", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q03717-1.655.655", "start_pos": 655, "end_pos": 655, "uniprot_canonical_ac": "Q03717-1", "length": 857, "uniprot_id": "KCNB1_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily B member 1", "refseq_ac": "NP_032446", "refseq_name": "potassium voltage-gated channel subfamily B member 1", "gene_name": "Kcnb1", "gene_names_uniprotkb": "Kcnb1", "gene_names_refseq": "Kcnb1; Kcr1-1; Kv2.1; Shab", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Comprehensive identification of phosphorylation sites in postsynaptic density preparations.", "journal": "Molecular & cellular proteomics : MCP", "date": "2006", "authors": "Trinidad JC, Specht CG, Thalhammer A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" }, { "database": "iPTMnet", "id": "Q03717", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03717" } ], "reference": [ { "type": "PubMed", "id": "16452087", "url": "https://glygen.org/publication/PubMed/16452087" } ] }, { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" }, { "database": "iPTMnet", "id": "Q03717", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03717" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "16452087", "url": "https://glygen.org/publication/PubMed/16452087", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q03717", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03717", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GRLMETNPIPEASRSGFFVE", "down_seq": "PRSSMKTHNPMKLRALKVNF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" }, { "database": "PubMed", "id": "16452087", "url": "https://glygen.org/publication/PubMed/16452087" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q03717", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03717" } ], "site_lbl": "Ser655" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "442", "end_pos": "442" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "711", "end_pos": "711" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "457", "end_pos": "457" }, { "start_pos": "484", "end_pos": "484" }, { "start_pos": "496", "end_pos": "496" }, { "start_pos": "503", "end_pos": "503" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "541", "end_pos": "541" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "655", "end_pos": "655" }, { "start_pos": "719", "end_pos": "719" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "799", "end_pos": "799" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "836", "end_pos": "836" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03717-1.719.719", "start_pos": 719, "end_pos": 719, "uniprot_canonical_ac": "Q03717-1", "length": 857, "uniprot_id": "KCNB1_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily B member 1", "refseq_ac": "NP_032446", "refseq_name": "potassium voltage-gated channel subfamily B member 1", "gene_name": "Kcnb1", "gene_names_uniprotkb": "Kcnb1", "gene_names_refseq": "Kcnb1; Kcr1-1; Kv2.1; Shab", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GAAAAVAGLECASLLDKPVL", "down_seq": "PESSIYTTASARTPPRSPEK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" } ], "site_lbl": "Ser719" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "442", "end_pos": "442" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "711", "end_pos": "711" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "457", "end_pos": "457" }, { "start_pos": "484", "end_pos": "484" }, { "start_pos": "496", "end_pos": "496" }, { "start_pos": "503", "end_pos": "503" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "541", "end_pos": "541" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "655", "end_pos": "655" }, { "start_pos": "719", "end_pos": "719" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "799", "end_pos": "799" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "836", "end_pos": "836" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "Q03717-1.711.711", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q03717-1.771.771", "start_pos": 771, "end_pos": 771, "uniprot_canonical_ac": "Q03717-1", "length": 857, "uniprot_id": "KCNB1_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily B member 1", "refseq_ac": "NP_032446", "refseq_name": "potassium voltage-gated channel subfamily B member 1", "gene_name": "Kcnb1", "gene_names_uniprotkb": "Kcnb1", "gene_names_refseq": "Kcnb1; Kcr1-1; Kv2.1; Shab", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VHQYIDTDTDDEGQLLYSVD", "down_seq": "SPPKSLHGSTSPKFSLGART", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" } ], "site_lbl": "Ser771" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "442", "end_pos": "442" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "711", "end_pos": "711" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "457", "end_pos": "457" }, { "start_pos": "484", "end_pos": "484" }, { "start_pos": "496", "end_pos": "496" }, { "start_pos": "503", "end_pos": "503" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "541", "end_pos": "541" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "655", "end_pos": "655" }, { "start_pos": "719", "end_pos": "719" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "799", "end_pos": "799" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "836", "end_pos": "836" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q03717-1.799.799", "start_pos": 799, "end_pos": 799, "uniprot_canonical_ac": "Q03717-1", "length": 857, "uniprot_id": "KCNB1_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily B member 1", "refseq_ac": "NP_032446", "refseq_name": "potassium voltage-gated channel subfamily B member 1", "gene_name": "Kcnb1", "gene_names_uniprotkb": "Kcnb1", "gene_names_refseq": "Kcnb1; Kcr1-1; Kv2.1; Shab", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GSTSPKFSLGARTEKNHFES", "down_seq": "PLPTSPKFLRPNCVYASEGL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" } ], "site_lbl": "Ser799" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "442", "end_pos": "442" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "711", "end_pos": "711" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "457", "end_pos": "457" }, { "start_pos": "484", "end_pos": "484" }, { "start_pos": "496", "end_pos": "496" }, { "start_pos": "503", "end_pos": "503" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "541", "end_pos": "541" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "655", "end_pos": "655" }, { "start_pos": "719", "end_pos": "719" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "799", "end_pos": "799" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "836", "end_pos": "836" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "upstream", "id": "Q03717-1.804.804", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q03717-1.804.804", "start_pos": 804, "end_pos": 804, "uniprot_canonical_ac": "Q03717-1", "length": 857, "uniprot_id": "KCNB1_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily B member 1", "refseq_ac": "NP_032446", "refseq_name": "potassium voltage-gated channel subfamily B member 1", "gene_name": "Kcnb1", "gene_names_uniprotkb": "Kcnb1", "gene_names_refseq": "Kcnb1; Kcr1-1; Kv2.1; Shab", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" }, { "database": "iPTMnet", "id": "Q03717", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03717" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q03717", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03717", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KFSLGARTEKNHFESSPLPT", "down_seq": "PKFLRPNCVYASEGLPGKGP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q03717", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03717" } ], "site_lbl": "Ser804" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "442", "end_pos": "442" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "711", "end_pos": "711" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "457", "end_pos": "457" }, { "start_pos": "484", "end_pos": "484" }, { "start_pos": "496", "end_pos": "496" }, { "start_pos": "503", "end_pos": "503" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "541", "end_pos": "541" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "655", "end_pos": "655" }, { "start_pos": "719", "end_pos": "719" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "799", "end_pos": "799" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "836", "end_pos": "836" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "Q03717-1.799.799", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03717-1.836.836", "start_pos": 836, "end_pos": 836, "uniprot_canonical_ac": "Q03717-1", "length": 857, "uniprot_id": "KCNB1_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily B member 1", "refseq_ac": "NP_032446", "refseq_name": "potassium voltage-gated channel subfamily B member 1", "gene_name": "Kcnb1", "gene_names_uniprotkb": "Kcnb1", "gene_names_refseq": "Kcnb1; Kcr1-1; Kv2.1; Shab", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "SEGLPGKGPGAQEKCKLENH", "down_seq": "SPDVHMLPGGGAHGSTRDQS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q03717", "url": "https://www.uniprot.org/uniprotkb/Q03717" } ], "site_lbl": "Thr836" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "442", "end_pos": "442" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "711", "end_pos": "711" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "128", "end_pos": "128" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "457", "end_pos": "457" }, { "start_pos": "484", "end_pos": "484" }, { "start_pos": "496", "end_pos": "496" }, { "start_pos": "503", "end_pos": "503" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "541", "end_pos": "541" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "590", "end_pos": "590" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "655", "end_pos": "655" }, { "start_pos": "719", "end_pos": "719" }, { "start_pos": "771", "end_pos": "771" }, { "start_pos": "799", "end_pos": "799" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "836", "end_pos": "836" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q03719-1.355.355", "start_pos": 355, "end_pos": 355, "uniprot_canonical_ac": "Q03719-1", "length": 651, "uniprot_id": "KCND1_MOUSE", "protein_name": "A-type voltage-gated potassium channel KCND1", "refseq_ac": "NP_032449", "refseq_name": "A-type voltage-gated potassium channel KCND1", "gene_name": "Kcnd1", "gene_names_uniprotkb": "Kcnd1", "gene_names_refseq": "1110037K09Rik; Kca2-1; Kcnd1; Kv4.1; Shal1; Shal; mShal1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03719", "url": "https://www.uniprot.org/uniprotkb/Q03719" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q03719", "url": "https://www.uniprot.org/uniprotkb/Q03719", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "MAIIIFATVMFYAEKGTSKT", "down_seq": "FTSIPAAFWYTIVTMTTLGY", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn355", "evidence": [ { "id": "Q03719", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q03719#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "355", "end_pos": "355" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "458", "end_pos": "458" }, { "start_pos": "555", "end_pos": "555" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q03719-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "Q03719-1", "length": 651, "uniprot_id": "KCND1_MOUSE", "protein_name": "A-type voltage-gated potassium channel KCND1", "refseq_ac": "NP_032449", "refseq_name": "A-type voltage-gated potassium channel KCND1", "gene_name": "Kcnd1", "gene_names_uniprotkb": "Kcnd1", "gene_names_refseq": "1110037K09Rik; Kca2-1; Kcnd1; Kv4.1; Shal1; Shal; mShal1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03719", "url": "https://www.uniprot.org/uniprotkb/Q03719" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q03719", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q03719" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] } ], "crossref": [ { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q03719", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q03719", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" }, { "id": "Q03719", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q03719" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "355", "end_pos": "355" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "458", "end_pos": "458" }, { "start_pos": "555", "end_pos": "555" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03719-1.458.458", "start_pos": 458, "end_pos": 458, "uniprot_canonical_ac": "Q03719-1", "length": 651, "uniprot_id": "KCND1_MOUSE", "protein_name": "A-type voltage-gated potassium channel KCND1", "refseq_ac": "NP_032449", "refseq_name": "A-type voltage-gated potassium channel KCND1", "gene_name": "Kcnd1", "gene_names_uniprotkb": "Kcnd1", "gene_names_refseq": "1110037K09Rik; Kca2-1; Kcnd1; Kv4.1; Shal1; Shal; mShal1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03719", "url": "https://www.uniprot.org/uniprotkb/Q03719" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q03719", "url": "https://www.uniprot.org/uniprotkb/Q03719" }, { "database": "iPTMnet", "id": "Q03719", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03719" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q03719", "url": "https://www.uniprot.org/uniprotkb/Q03719", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q03719", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03719", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AKSGTTNAFLQYKQNGGLED", "down_seq": "GSGDGQMLCVRSRSAFEQQH", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q03719", "url": "https://www.uniprot.org/uniprotkb/Q03719" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q03719", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03719" } ], "site_lbl": "Ser458" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "355", "end_pos": "355" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "458", "end_pos": "458" }, { "start_pos": "555", "end_pos": "555" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q03719-1.555.555", "start_pos": 555, "end_pos": 555, "uniprot_canonical_ac": "Q03719-1", "length": 651, "uniprot_id": "KCND1_MOUSE", "protein_name": "A-type voltage-gated potassium channel KCND1", "refseq_ac": "NP_032449", "refseq_name": "A-type voltage-gated potassium channel KCND1", "gene_name": "Kcnd1", "gene_names_uniprotkb": "Kcnd1", "gene_names_refseq": "1110037K09Rik; Kca2-1; Kcnd1; Kv4.1; Shal1; Shal; mShal1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q03719", "url": "https://www.uniprot.org/uniprotkb/Q03719" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q03719", "url": "https://www.uniprot.org/uniprotkb/Q03719" }, { "database": "iPTMnet", "id": "Q03719", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03719" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q03719", "url": "https://www.uniprot.org/uniprotkb/Q03719", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q03719", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03719", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RRVNRRAIRLANSTASVSRG", "down_seq": "MQELDTLAGLRRSPAPQTRS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q03719", "url": "https://www.uniprot.org/uniprotkb/Q03719" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q03719", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03719" } ], "site_lbl": "Ser555" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "355", "end_pos": "355" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "458", "end_pos": "458" }, { "start_pos": "555", "end_pos": "555" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q61410-1.239.239", "start_pos": 239, "end_pos": 239, "uniprot_canonical_ac": "Q61410-1", "length": 762, "uniprot_id": "KGP2_MOUSE", "protein_name": "cGMP-dependent protein kinase 2", "refseq_ac": "", "refseq_name": "", "gene_name": "Prkg2", "gene_names_uniprotkb": "Prkg2; Prkgr2", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q61410", "url": "https://www.uniprot.org/uniprotkb/Q61410" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "EKLLSSIPMWTTFGELAILY", "down_seq": "CTRTASVKAITNVKTWALDR", "glycosylation": [ { "glytoucan_ac": "G59924QI", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "LLSSIPMWTTFGELAILYNCTR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn239", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "239", "end_pos": "239" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "110", "end_pos": "110" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "609", "end_pos": "609" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q61410-1.110.110", "start_pos": 110, "end_pos": 110, "uniprot_canonical_ac": "Q61410-1", "length": 762, "uniprot_id": "KGP2_MOUSE", "protein_name": "cGMP-dependent protein kinase 2", "refseq_ac": "", "refseq_name": "", "gene_name": "Prkg2", "gene_names_uniprotkb": "Prkg2; Prkgr2", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q61410", "url": "https://www.uniprot.org/uniprotkb/Q61410" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q61410", "url": "https://www.uniprot.org/uniprotkb/Q61410", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GGSPLQASPDKVPLDVHRKT", "down_seq": "GLVSLHSRRGAKAGVSAEPT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q61410", "url": "https://www.uniprot.org/uniprotkb/Q61410" } ], "site_lbl": "Ser110" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "239", "end_pos": "239" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "110", "end_pos": "110" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "609", "end_pos": "609" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "upstream", "id": "Q61410-1.117.117", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q61410-1.117.117", "start_pos": 117, "end_pos": 117, "uniprot_canonical_ac": "Q61410-1", "length": 762, "uniprot_id": "KGP2_MOUSE", "protein_name": "cGMP-dependent protein kinase 2", "refseq_ac": "", "refseq_name": "", "gene_name": "Prkg2", "gene_names_uniprotkb": "Prkg2; Prkgr2", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q61410", "url": "https://www.uniprot.org/uniprotkb/Q61410" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q61410", "url": "https://www.uniprot.org/uniprotkb/Q61410", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SPDKVPLDVHRKTSGLVSLH", "down_seq": "RRGAKAGVSAEPTTRTYDLN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q61410", "url": "https://www.uniprot.org/uniprotkb/Q61410" } ], "site_lbl": "Ser117" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "239", "end_pos": "239" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "110", "end_pos": "110" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "609", "end_pos": "609" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "Q61410-1.110.110", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q61410-1.431.431", "start_pos": 431, "end_pos": 431, "uniprot_canonical_ac": "Q61410-1", "length": 762, "uniprot_id": "KGP2_MOUSE", "protein_name": "cGMP-dependent protein kinase 2", "refseq_ac": "", "refseq_name": "", "gene_name": "Prkg2", "gene_names_uniprotkb": "Prkg2; Prkgr2", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q61410", "url": "https://www.uniprot.org/uniprotkb/Q61410" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q61410", "url": "https://www.uniprot.org/uniprotkb/Q61410", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DDEKRHAKRSMSSWKLSKAL", "down_seq": "LEMIQLKEKVARFSSTSPFQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q61410", "url": "https://www.uniprot.org/uniprotkb/Q61410" } ], "site_lbl": "Ser431" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "239", "end_pos": "239" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "110", "end_pos": "110" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "609", "end_pos": "609" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q61410-1.609.609", "start_pos": 609, "end_pos": 609, "uniprot_canonical_ac": "Q61410-1", "length": 762, "uniprot_id": "KGP2_MOUSE", "protein_name": "cGMP-dependent protein kinase 2", "refseq_ac": "", "refseq_name": "", "gene_name": "Prkg2", "gene_names_uniprotkb": "Prkg2; Prkgr2", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q61410", "url": "https://www.uniprot.org/uniprotkb/Q61410" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q61410", "url": "https://www.uniprot.org/uniprotkb/Q61410" }, { "database": "iPTMnet", "id": "Q61410", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q61410" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q61410", "url": "https://www.uniprot.org/uniprotkb/Q61410", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q61410", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q61410", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "YLKLVDFGFAKKIGSGQKTW", "down_seq": "FCGTPEYVAPEVILNKGHDF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q61410", "url": "https://www.uniprot.org/uniprotkb/Q61410" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q61410", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q61410" } ], "site_lbl": "Thr609" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "239", "end_pos": "239" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "110", "end_pos": "110" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "609", "end_pos": "609" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6NZK5-1.300.300", "start_pos": 300, "end_pos": 300, "uniprot_canonical_ac": "Q6NZK5-1", "length": 612, "uniprot_id": "K1328_MOUSE", "protein_name": "Protein hinderin", "refseq_ac": "NP_001028704", "refseq_name": "protein hinderin isoform 1", "gene_name": "AW554918; Kiaa1328", "gene_names_uniprotkb": "AW554918; Kiaa1328", "gene_names_refseq": "4921538P22; AW554918; Kiaa1328; mKIAA1328", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6NZK5", "url": "https://www.uniprot.org/uniprotkb/Q6NZK5" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "PIEKSLPVELKIKEYPNLPP", "down_seq": "PSSQYCGHKCSESGAYVHEN", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr300", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "300", "end_pos": "300" } ] }, { "type": "snv", "site_list": [ { "start_pos": "416", "end_pos": "416" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "178", "end_pos": "178" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "558", "end_pos": "558" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q6NZK5-1.416.416", "start_pos": 416, "end_pos": 416, "uniprot_canonical_ac": "Q6NZK5-1", "length": 612, "uniprot_id": "K1328_MOUSE", "protein_name": "Protein hinderin", "refseq_ac": "NP_001028704", "refseq_name": "protein hinderin isoform 1", "gene_name": "AW554918; Kiaa1328", "gene_names_uniprotkb": "AW554918; Kiaa1328", "gene_names_refseq": "4921538P22; AW554918; Kiaa1328; mKIAA1328", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6NZK5", "url": "https://www.uniprot.org/uniprotkb/Q6NZK5" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs238691590", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs238691590", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "L", "start_aa": "L", "up_seq": "ETKLLLKQQQLHQSRLDYNW", "down_seq": "RTQAMFKSRELVADKEFPKP", "snv": [ { "evidence": [ { "id": "rs238691590", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs238691590" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "L", "sequence_mut": "S", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (NWL->NWS).", "chr_id": "18", "chr_pos": "25532985", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "L416", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "300", "end_pos": "300" } ] }, { "type": "snv", "site_list": [ { "start_pos": "416", "end_pos": "416" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "178", "end_pos": "178" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "558", "end_pos": "558" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q6NZK5-1.178.178", "start_pos": 178, "end_pos": 178, "uniprot_canonical_ac": "Q6NZK5-1", "length": 612, "uniprot_id": "K1328_MOUSE", "protein_name": "Protein hinderin", "refseq_ac": "NP_001028704", "refseq_name": "protein hinderin isoform 1", "gene_name": "AW554918; Kiaa1328", "gene_names_uniprotkb": "AW554918; Kiaa1328", "gene_names_refseq": "4921538P22; AW554918; Kiaa1328; mKIAA1328", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6NZK5", "url": "https://www.uniprot.org/uniprotkb/Q6NZK5" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q6NZK5", "url": "https://www.uniprot.org/uniprotkb/Q6NZK5", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QELLSLYQKYLSEQQEKLTL", "down_seq": "LSELGAARAQEQQITKKKNT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q6NZK5", "url": "https://www.uniprot.org/uniprotkb/Q6NZK5" } ], "site_lbl": "Ser178" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "300", "end_pos": "300" } ] }, { "type": "snv", "site_list": [ { "start_pos": "416", "end_pos": "416" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "178", "end_pos": "178" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "558", "end_pos": "558" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q6NZK5-1.20.20", "start_pos": 20, "end_pos": 20, "uniprot_canonical_ac": "Q6NZK5-1", "length": 612, "uniprot_id": "K1328_MOUSE", "protein_name": "Protein hinderin", "refseq_ac": "NP_001028704", "refseq_name": "protein hinderin isoform 1", "gene_name": "AW554918; Kiaa1328", "gene_names_uniprotkb": "AW554918; Kiaa1328", "gene_names_refseq": "4921538P22; AW554918; Kiaa1328; mKIAA1328", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6NZK5", "url": "https://www.uniprot.org/uniprotkb/Q6NZK5" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q6NZK5", "url": "https://www.uniprot.org/uniprotkb/Q6NZK5" }, { "database": "iPTMnet", "id": "Q6NZK5", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6NZK5" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q6NZK5", "url": "https://www.uniprot.org/uniprotkb/Q6NZK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q6NZK5", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6NZK5", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "", "down_seq": "DEDQSVAYVPGISTEGNTRS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q6NZK5", "url": "https://www.uniprot.org/uniprotkb/Q6NZK5" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q6NZK5", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6NZK5" } ], "site_lbl": "Ser20" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "300", "end_pos": "300" } ] }, { "type": "snv", "site_list": [ { "start_pos": "416", "end_pos": "416" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "178", "end_pos": "178" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "558", "end_pos": "558" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6NZK5-1.471.471", "start_pos": 471, "end_pos": 471, "uniprot_canonical_ac": "Q6NZK5-1", "length": 612, "uniprot_id": "K1328_MOUSE", "protein_name": "Protein hinderin", "refseq_ac": "NP_001028704", "refseq_name": "protein hinderin isoform 1", "gene_name": "AW554918; Kiaa1328", "gene_names_uniprotkb": "AW554918; Kiaa1328", "gene_names_refseq": "4921538P22; AW554918; Kiaa1328; mKIAA1328", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6NZK5", "url": "https://www.uniprot.org/uniprotkb/Q6NZK5" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q6NZK5", "url": "https://www.uniprot.org/uniprotkb/Q6NZK5" }, { "database": "iPTMnet", "id": "Q6NZK5", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6NZK5" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q6NZK5", "url": "https://www.uniprot.org/uniprotkb/Q6NZK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q6NZK5", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6NZK5", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KPKCDGWMRGTSTSFKKCPD", "down_seq": "PNSGQNQREKKTVEFQSRVE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q6NZK5", "url": "https://www.uniprot.org/uniprotkb/Q6NZK5" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q6NZK5", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6NZK5" } ], "site_lbl": "Ser471" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "300", "end_pos": "300" } ] }, { "type": "snv", "site_list": [ { "start_pos": "416", "end_pos": "416" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "178", "end_pos": "178" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "558", "end_pos": "558" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6NZK5-1.527.527", "start_pos": 527, "end_pos": 527, "uniprot_canonical_ac": "Q6NZK5-1", "length": 612, "uniprot_id": "K1328_MOUSE", "protein_name": "Protein hinderin", "refseq_ac": "NP_001028704", "refseq_name": "protein hinderin isoform 1", "gene_name": "AW554918; Kiaa1328", "gene_names_uniprotkb": "AW554918; Kiaa1328", "gene_names_refseq": "4921538P22; AW554918; Kiaa1328; mKIAA1328", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6NZK5", "url": "https://www.uniprot.org/uniprotkb/Q6NZK5" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q6NZK5", "url": "https://www.uniprot.org/uniprotkb/Q6NZK5", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QRETVTGVRKDASTSPMSTR", "down_seq": "PKEPLTPASLSSQHKTSRYE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q6NZK5", "url": "https://www.uniprot.org/uniprotkb/Q6NZK5" } ], "site_lbl": "Ser527" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "300", "end_pos": "300" } ] }, { "type": "snv", "site_list": [ { "start_pos": "416", "end_pos": "416" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "178", "end_pos": "178" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "558", "end_pos": "558" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q6NZK5-1.558.558", "start_pos": 558, "end_pos": 558, "uniprot_canonical_ac": "Q6NZK5-1", "length": 612, "uniprot_id": "K1328_MOUSE", "protein_name": "Protein hinderin", "refseq_ac": "NP_001028704", "refseq_name": "protein hinderin isoform 1", "gene_name": "AW554918; Kiaa1328", "gene_names_uniprotkb": "AW554918; Kiaa1328", "gene_names_refseq": "4921538P22; AW554918; Kiaa1328; mKIAA1328", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6NZK5", "url": "https://www.uniprot.org/uniprotkb/Q6NZK5" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q6NZK5", "url": "https://www.uniprot.org/uniprotkb/Q6NZK5" }, { "database": "iPTMnet", "id": "Q6NZK5", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6NZK5" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q6NZK5", "url": "https://www.uniprot.org/uniprotkb/Q6NZK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q6NZK5", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6NZK5", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SSQHKTSRYETSLLDLVQSL", "down_seq": "PNSAPKSQPHPSRAAGTWST", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q6NZK5", "url": "https://www.uniprot.org/uniprotkb/Q6NZK5" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q6NZK5", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6NZK5" } ], "site_lbl": "Ser558" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "300", "end_pos": "300" } ] }, { "type": "snv", "site_list": [ { "start_pos": "416", "end_pos": "416" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "178", "end_pos": "178" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "558", "end_pos": "558" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6VV64-1.83.83", "start_pos": 83, "end_pos": 83, "uniprot_canonical_ac": "Q6VV64-1", "length": 394, "uniprot_id": "KCNKI_MOUSE", "protein_name": "Potassium channel subfamily K member 18", "refseq_ac": "NP_997144", "refseq_name": "potassium channel subfamily K member 18", "gene_name": "Kcnk18", "gene_names_uniprotkb": "Kcnk18; Tresk-2; Tresk2", "gene_names_refseq": "Gm781; Kcnk18; Tresk-2; Tresk; Trik", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6VV64", "url": "https://www.uniprot.org/uniprotkb/Q6VV64" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "N-linked glycosylation determines cell surface expression of two-pore-domain K+ channel TRESK.", "journal": "Biochemical and biophysical research communications", "date": "2010", "authors": "Egenberger B, Polleichtner G, Wischmeyer E, Doring F", "evidence": [ { "database": "UniProtKB", "id": "Q6VV64", "url": "https://www.uniprot.org/uniprotkb/Q6VV64#ptm_processing" }, { "database": "UniProtKB", "id": "Q6VV64", "url": "https://www.uniprot.org/uniprotkb/Q6VV64" } ], "reference": [ { "type": "PubMed", "id": "20006580", "url": "https://glygen.org/publication/PubMed/20006580" } ] } ], "crossref": [ { "id": "Q6VV64", "url": "https://www.uniprot.org/uniprotkb/Q6VV64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "20006580", "url": "https://glygen.org/publication/PubMed/20006580", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "AEENPELKKFLDDLCNILKC", "down_seq": "LTVVEGSRKNLCEHLQHLKP", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn83", "evidence": [ { "id": "Q6VV64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6VV64#ptm_processing" }, { "id": "20006580", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/20006580" } ] } ], "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "Q", "comment": "Strongly reduced current amplitude and localization to cell membrane.", "evidence": [ { "database": "UniProtKB", "id": "Q6VV64", "url": "https://www.uniprot.org/uniprotkb/Q6VV64" }, { "database": "PubMed", "id": "20006580", "url": "https://glygen.org/publication/PubMed/20006580" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "83", "end_pos": "83" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "131", "end_pos": "131" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "264", "end_pos": "264" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "83", "end_pos": "83" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "264", "end_pos": "264" }, { "start_pos": "276", "end_pos": "276" } ] } ], "categories": [ "glycosylation_flag", "mutagenesis_flag" ], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6VV64-1.131.131", "start_pos": 131, "end_pos": 131, "uniprot_canonical_ac": "Q6VV64-1", "length": 394, "uniprot_id": "KCNKI_MOUSE", "protein_name": "Potassium channel subfamily K member 18", "refseq_ac": "NP_997144", "refseq_name": "potassium channel subfamily K member 18", "gene_name": "Kcnk18", "gene_names_uniprotkb": "Kcnk18; Tresk-2; Tresk2", "gene_names_refseq": "Gm781; Kcnk18; Tresk-2; Tresk; Trik", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6VV64", "url": "https://www.uniprot.org/uniprotkb/Q6VV64" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "TRESK and TREK-2 two-pore-domain potassium channel subunits form functional heterodimers in primary somatosensory neurons.", "journal": "The Journal of biological chemistry", "date": "2020", "authors": "Lengyel M, Czirjak G, Jacobson DA, Enyedi P", "evidence": [ { "database": "UniProtKB", "id": "Q6VV64", "url": "https://www.uniprot.org/uniprotkb/Q6VV64" } ], "reference": [ { "type": "PubMed", "id": "32641496", "url": "https://glygen.org/publication/PubMed/32641496" } ] } ], "crossref": [ { "id": "Q6VV64", "url": "https://www.uniprot.org/uniprotkb/Q6VV64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "32641496", "url": "https://glygen.org/publication/PubMed/32641496", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "G", "start_aa": "G", "up_seq": "DWSFLSALFFCCTVFSTVGY", "down_seq": "HMYPVTRLGKFLCMLYALFG", "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "E", "comment": "Acts as a dominant negative on wild-type KCNK18 or KCNK10 subunits.", "evidence": [ { "database": "UniProtKB", "id": "Q6VV64", "url": "https://www.uniprot.org/uniprotkb/Q6VV64" }, { "database": "PubMed", "id": "32641496", "url": "https://glygen.org/publication/PubMed/32641496" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "83", "end_pos": "83" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "131", "end_pos": "131" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "264", "end_pos": "264" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "83", "end_pos": "83" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "264", "end_pos": "264" }, { "start_pos": "276", "end_pos": "276" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "Q6VV64-1.132.132", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6VV64-1.132.132", "start_pos": 132, "end_pos": 132, "uniprot_canonical_ac": "Q6VV64-1", "length": 394, "uniprot_id": "KCNKI_MOUSE", "protein_name": "Potassium channel subfamily K member 18", "refseq_ac": "NP_997144", "refseq_name": "potassium channel subfamily K member 18", "gene_name": "Kcnk18", "gene_names_uniprotkb": "Kcnk18; Tresk-2; Tresk2", "gene_names_refseq": "Gm781; Kcnk18; Tresk-2; Tresk; Trik", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6VV64", "url": "https://www.uniprot.org/uniprotkb/Q6VV64" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "TRESK two-pore-domain K+ channels constitute a significant component of background potassium currents in murine dorsal root ganglion neurones.", "journal": "The Journal of physiology", "date": "2007", "authors": "Dobler T, Springauf A, Tovornik S, Weber M, Schmitt A, Sedlmeier R, Wischmeyer E, Doring F", "evidence": [ { "database": "UniProtKB", "id": "Q6VV64", "url": "https://www.uniprot.org/uniprotkb/Q6VV64" } ], "reference": [ { "type": "PubMed", "id": "17962323", "url": "https://glygen.org/publication/PubMed/17962323" } ] } ], "crossref": [ { "id": "Q6VV64", "url": "https://www.uniprot.org/uniprotkb/Q6VV64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17962323", "url": "https://glygen.org/publication/PubMed/17962323", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "H", "start_aa": "H", "up_seq": "WSFLSALFFCCTVFSTVGYG", "down_seq": "MYPVTRLGKFLCMLYALFGI", "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "N", "comment": "Insensitive to extracellular protons.", "evidence": [ { "database": "UniProtKB", "id": "Q6VV64", "url": "https://www.uniprot.org/uniprotkb/Q6VV64" }, { "database": "PubMed", "id": "17962323", "url": "https://glygen.org/publication/PubMed/17962323" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "83", "end_pos": "83" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "131", "end_pos": "131" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "264", "end_pos": "264" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "83", "end_pos": "83" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "264", "end_pos": "264" }, { "start_pos": "276", "end_pos": "276" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "Q6VV64-1.131.131", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6VV64-1.212.212", "start_pos": 212, "end_pos": 212, "uniprot_canonical_ac": "Q6VV64-1", "length": 394, "uniprot_id": "KCNKI_MOUSE", "protein_name": "Potassium channel subfamily K member 18", "refseq_ac": "NP_997144", "refseq_name": "potassium channel subfamily K member 18", "gene_name": "Kcnk18", "gene_names_uniprotkb": "Kcnk18; Tresk-2; Tresk2", "gene_names_refseq": "Gm781; Kcnk18; Tresk-2; Tresk; Trik", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6VV64", "url": "https://www.uniprot.org/uniprotkb/Q6VV64" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Targeting of calcineurin to an NFAT-like docking site is required for the calcium-dependent activation of the background K+ channel, TRESK.", "journal": "The Journal of biological chemistry", "date": "2006", "authors": "Czirjak G, Enyedi P", "evidence": [ { "database": "UniProtKB", "id": "Q6VV64", "url": "https://www.uniprot.org/uniprotkb/Q6VV64" }, { "database": "RefSeq", "id": "NP_997144", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_997144" } ], "reference": [ { "type": "PubMed", "id": "16569637", "url": "https://glygen.org/publication/PubMed/16569637" } ] } ], "crossref": [ { "id": "Q6VV64", "url": "https://www.uniprot.org/uniprotkb/Q6VV64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "16569637", "url": "https://glygen.org/publication/PubMed/16569637", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "I", "start_aa": "I", "up_seq": "SLPLCRKQPDSKPVEEAIPQ", "down_seq": "VIDAGVDELLNPQPSKDPPS", "mutagenesis": [ { "sequence_org": "I", "sequence_mut": "A", "comment": "Loss of interaction with calcineurin and activation by elevated intracellular calcium; when associated with A-214.", "evidence": [ { "database": "UniProtKB", "id": "Q6VV64", "url": "https://www.uniprot.org/uniprotkb/Q6VV64" }, { "database": "PubMed", "id": "16569637", "url": "https://glygen.org/publication/PubMed/16569637" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "83", "end_pos": "83" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "131", "end_pos": "131" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "264", "end_pos": "264" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "83", "end_pos": "83" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "264", "end_pos": "264" }, { "start_pos": "276", "end_pos": "276" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "Q6VV64-1.214.214", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6VV64-1.214.214", "start_pos": 214, "end_pos": 214, "uniprot_canonical_ac": "Q6VV64-1", "length": 394, "uniprot_id": "KCNKI_MOUSE", "protein_name": "Potassium channel subfamily K member 18", "refseq_ac": "NP_997144", "refseq_name": "potassium channel subfamily K member 18", "gene_name": "Kcnk18", "gene_names_uniprotkb": "Kcnk18; Tresk-2; Tresk2", "gene_names_refseq": "Gm781; Kcnk18; Tresk-2; Tresk; Trik", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6VV64", "url": "https://www.uniprot.org/uniprotkb/Q6VV64" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Targeting of calcineurin to an NFAT-like docking site is required for the calcium-dependent activation of the background K+ channel, TRESK.", "journal": "The Journal of biological chemistry", "date": "2006", "authors": "Czirjak G, Enyedi P", "evidence": [ { "database": "UniProtKB", "id": "Q6VV64", "url": "https://www.uniprot.org/uniprotkb/Q6VV64" }, { "database": "RefSeq", "id": "NP_997144", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_997144" } ], "reference": [ { "type": "PubMed", "id": "16569637", "url": "https://glygen.org/publication/PubMed/16569637" } ] } ], "crossref": [ { "id": "Q6VV64", "url": "https://www.uniprot.org/uniprotkb/Q6VV64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "16569637", "url": "https://glygen.org/publication/PubMed/16569637", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "I", "start_aa": "I", "up_seq": "PLCRKQPDSKPVEEAIPQIV", "down_seq": "DAGVDELLNPQPSKDPPSPS", "mutagenesis": [ { "sequence_org": "I", "sequence_mut": "A", "comment": "Strongly reduced activation by elevated intracellular Ca(2+). Loss of interaction with calcineurin and activation by elevated intracellular Ca(2+); when associated with A-212.", "evidence": [ { "database": "UniProtKB", "id": "Q6VV64", "url": "https://www.uniprot.org/uniprotkb/Q6VV64" }, { "database": "PubMed", "id": "16569637", "url": "https://glygen.org/publication/PubMed/16569637" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "83", "end_pos": "83" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "131", "end_pos": "131" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "264", "end_pos": "264" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "83", "end_pos": "83" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "264", "end_pos": "264" }, { "start_pos": "276", "end_pos": "276" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "Q6VV64-1.212.212", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6VV64-1.264.264", "start_pos": 264, "end_pos": 264, "uniprot_canonical_ac": "Q6VV64-1", "length": 394, "uniprot_id": "KCNKI_MOUSE", "protein_name": "Potassium channel subfamily K member 18", "refseq_ac": "NP_997144", "refseq_name": "potassium channel subfamily K member 18", "gene_name": "Kcnk18", "gene_names_uniprotkb": "Kcnk18; Tresk-2; Tresk2", "gene_names_refseq": "Gm781; Kcnk18; Tresk-2; Tresk; Trik", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6VV64", "url": "https://www.uniprot.org/uniprotkb/Q6VV64" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Phosphorylation-dependent binding of 14-3-3 proteins controls TRESK regulation.", "journal": "The Journal of biological chemistry", "date": "2008", "authors": "Czirjak G, Vuity D, Enyedi P", "evidence": [ { "database": "UniProtKB", "id": "Q6VV64", "url": "https://www.uniprot.org/uniprotkb/Q6VV64" }, { "database": "iPTMnet", "id": "Q6VV64", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6VV64" } ], "reference": [ { "type": "PubMed", "id": "18397886", "url": "https://glygen.org/publication/PubMed/18397886" } ] }, { "title": "TRESK and TREK-2 two-pore-domain potassium channel subunits form functional heterodimers in primary somatosensory neurons.", "journal": "The Journal of biological chemistry", "date": "2020", "authors": "Lengyel M, Czirjak G, Jacobson DA, Enyedi P", "evidence": [ { "database": "UniProtKB", "id": "Q6VV64", "url": "https://www.uniprot.org/uniprotkb/Q6VV64" } ], "reference": [ { "type": "PubMed", "id": "32641496", "url": "https://glygen.org/publication/PubMed/32641496" } ] } ], "crossref": [ { "id": "Q6VV64", "url": "https://www.uniprot.org/uniprotkb/Q6VV64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18397886", "url": "https://glygen.org/publication/PubMed/18397886", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32641496", "url": "https://glygen.org/publication/PubMed/32641496", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q6VV64", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6VV64", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VAREKKNKLQPPTRPVERSN", "down_seq": "CPELVLGRLSCSILSNLDEV", "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Loss of interaction with YWHAH. No effect on channel conductance.", "evidence": [ { "database": "UniProtKB", "id": "Q6VV64", "url": "https://www.uniprot.org/uniprotkb/Q6VV64" }, { "database": "PubMed", "id": "18397886", "url": "https://glygen.org/publication/PubMed/18397886" }, { "database": "PubMed", "id": "32641496", "url": "https://glygen.org/publication/PubMed/32641496" } ] }, { "sequence_org": "S", "sequence_mut": "E", "comment": "Further decreases the open probability of the channel, without affecting the single channel conductance; when associated with E-276.", "evidence": [ { "database": "UniProtKB", "id": "Q6VV64", "url": "https://www.uniprot.org/uniprotkb/Q6VV64" }, { "database": "PubMed", "id": "32641496", "url": "https://glygen.org/publication/PubMed/32641496" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q6VV64", "url": "https://www.uniprot.org/uniprotkb/Q6VV64" }, { "database": "PubMed", "id": "18397886", "url": "https://glygen.org/publication/PubMed/18397886" }, { "database": "iPTMnet", "id": "Q6VV64", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6VV64" } ], "site_lbl": "Ser264" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "83", "end_pos": "83" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "131", "end_pos": "131" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "264", "end_pos": "264" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "83", "end_pos": "83" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "264", "end_pos": "264" }, { "start_pos": "276", "end_pos": "276" } ] } ], "categories": [ "mutagenesis_flag", "phosphorylation_flag" ], "glycosylation": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "upstream", "id": "Q6VV64-1.276.276", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6VV64-1.276.276", "start_pos": 276, "end_pos": 276, "uniprot_canonical_ac": "Q6VV64-1", "length": 394, "uniprot_id": "KCNKI_MOUSE", "protein_name": "Potassium channel subfamily K member 18", "refseq_ac": "NP_997144", "refseq_name": "potassium channel subfamily K member 18", "gene_name": "Kcnk18", "gene_names_uniprotkb": "Kcnk18; Tresk-2; Tresk2", "gene_names_refseq": "Gm781; Kcnk18; Tresk-2; Tresk; Trik", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6VV64", "url": "https://www.uniprot.org/uniprotkb/Q6VV64" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "The two-pore domain K+ channel, TRESK, is activated by the cytoplasmic calcium signal through calcineurin.", "journal": "The Journal of biological chemistry", "date": "2004", "authors": "Czirjak G, Toth ZE, Enyedi P", "evidence": [ { "database": "UniProtKB", "id": "Q6VV64", "url": "https://www.uniprot.org/uniprotkb/Q6VV64" }, { "database": "iPTMnet", "id": "Q6VV64", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6VV64" } ], "reference": [ { "type": "PubMed", "id": "14981085", "url": "https://glygen.org/publication/PubMed/14981085" } ] }, { "title": "TRESK and TREK-2 two-pore-domain potassium channel subunits form functional heterodimers in primary somatosensory neurons.", "journal": "The Journal of biological chemistry", "date": "2020", "authors": "Lengyel M, Czirjak G, Jacobson DA, Enyedi P", "evidence": [ { "database": "UniProtKB", "id": "Q6VV64", "url": "https://www.uniprot.org/uniprotkb/Q6VV64" } ], "reference": [ { "type": "PubMed", "id": "32641496", "url": "https://glygen.org/publication/PubMed/32641496" } ] }, { "title": "K2P18.1 translates T cell receptor signals into thymic regulatory T cell development.", "journal": "Cell research", "date": "2022-01", "authors": "Ruck Tobias, Bock Stefanie, Pfeuffer Steffen, Schroeter Christina B, Cengiz Derya, Marciniak Paul, Lindner Maren, Herrmann Alexander, Liebmann Marie, Kovac Stjepana, Gola Lukas, Rolfes Leoni, Pawlitzki Marc, Opel Nils, Hahn Tim, Dannlowski Udo, Pap Thomas, Luessi Felix, Schreiber Julian A, W\u00fcnsch Bernhard, Kuhlmann Tanja, Seebohm Guiscard, Tackenberg Bj\u00f6rn, Seja Patricia, D\u00f6ring Frank, Wischmeyer Erhard, Chasan Achmet Imam, Roth Johannes, Klotz Luisa, Meyer Zu H\u00f6rste Gerd, Wiendl Heinz, Marschall Tobias, Floess Stefan, Huehn Jochen, Budde Thomas, Bopp Tobias, Bittner Stefan, Meuth Sven G", "evidence": [ { "database": "UniProtKB", "id": "Q6VV64", "url": "https://www.uniprot.org/uniprotkb/Q6VV64" } ], "reference": [ { "type": "PubMed", "id": "34702947", "url": "https://glygen.org/publication/PubMed/34702947" } ] } ], "crossref": [ { "id": "Q6VV64", "url": "https://www.uniprot.org/uniprotkb/Q6VV64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "14981085", "url": "https://glygen.org/publication/PubMed/14981085", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32641496", "url": "https://glygen.org/publication/PubMed/32641496", "database": "PubMed", "categories": [ "Other" ] }, { "id": "34702947", "url": "https://glygen.org/publication/PubMed/34702947", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q6VV64", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6VV64", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TRPVERSNSCPELVLGRLSC", "down_seq": "ILSNLDEVGQQVERLDIPLP", "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Increases the open probability of the channel, without affecting the single channel conductance. Confers resistance to stimulation by calcineurin. Mice carrying the mutant allele display increased Treg numbers in thymus and spleen.", "evidence": [ { "database": "UniProtKB", "id": "Q6VV64", "url": "https://www.uniprot.org/uniprotkb/Q6VV64" }, { "database": "PubMed", "id": "14981085", "url": "https://glygen.org/publication/PubMed/14981085" }, { "database": "PubMed", "id": "32641496", "url": "https://glygen.org/publication/PubMed/32641496" }, { "database": "PubMed", "id": "34702947", "url": "https://glygen.org/publication/PubMed/34702947" } ] }, { "sequence_org": "S", "sequence_mut": "E", "comment": "Decreases the open probability of the channel, without affecting the single channel conductance.", "evidence": [ { "database": "UniProtKB", "id": "Q6VV64", "url": "https://www.uniprot.org/uniprotkb/Q6VV64" }, { "database": "PubMed", "id": "32641496", "url": "https://glygen.org/publication/PubMed/32641496" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q6VV64", "url": "https://www.uniprot.org/uniprotkb/Q6VV64" }, { "database": "PubMed", "id": "14981085", "url": "https://glygen.org/publication/PubMed/14981085" }, { "database": "iPTMnet", "id": "Q6VV64", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6VV64" } ], "site_lbl": "Ser276" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "83", "end_pos": "83" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "131", "end_pos": "131" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "264", "end_pos": "264" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "83", "end_pos": "83" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "264", "end_pos": "264" }, { "start_pos": "276", "end_pos": "276" } ] } ], "categories": [ "mutagenesis_flag", "phosphorylation_flag" ], "glycosylation": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "Q6VV64-1.264.264", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6VV64-1.339.339", "start_pos": 339, "end_pos": 339, "uniprot_canonical_ac": "Q6VV64-1", "length": 394, "uniprot_id": "KCNKI_MOUSE", "protein_name": "Potassium channel subfamily K member 18", "refseq_ac": "NP_997144", "refseq_name": "potassium channel subfamily K member 18", "gene_name": "Kcnk18", "gene_names_uniprotkb": "Kcnk18; Tresk-2; Tresk2", "gene_names_refseq": "Gm781; Kcnk18; Tresk-2; Tresk; Trik", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6VV64", "url": "https://www.uniprot.org/uniprotkb/Q6VV64" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "TRESK two-pore-domain K+ channels constitute a significant component of background potassium currents in murine dorsal root ganglion neurones.", "journal": "The Journal of physiology", "date": "2007", "authors": "Dobler T, Springauf A, Tovornik S, Weber M, Schmitt A, Sedlmeier R, Wischmeyer E, Doring F", "evidence": [ { "database": "UniProtKB", "id": "Q6VV64", "url": "https://www.uniprot.org/uniprotkb/Q6VV64" } ], "reference": [ { "type": "PubMed", "id": "17962323", "url": "https://glygen.org/publication/PubMed/17962323" } ] }, { "title": "K2P18.1 translates T cell receptor signals into thymic regulatory T cell development.", "journal": "Cell research", "date": "2022-01", "authors": "Ruck Tobias, Bock Stefanie, Pfeuffer Steffen, Schroeter Christina B, Cengiz Derya, Marciniak Paul, Lindner Maren, Herrmann Alexander, Liebmann Marie, Kovac Stjepana, Gola Lukas, Rolfes Leoni, Pawlitzki Marc, Opel Nils, Hahn Tim, Dannlowski Udo, Pap Thomas, Luessi Felix, Schreiber Julian A, W\u00fcnsch Bernhard, Kuhlmann Tanja, Seebohm Guiscard, Tackenberg Bj\u00f6rn, Seja Patricia, D\u00f6ring Frank, Wischmeyer Erhard, Chasan Achmet Imam, Roth Johannes, Klotz Luisa, Meyer Zu H\u00f6rste Gerd, Wiendl Heinz, Marschall Tobias, Floess Stefan, Huehn Jochen, Budde Thomas, Bopp Tobias, Bittner Stefan, Meuth Sven G", "evidence": [ { "database": "UniProtKB", "id": "Q6VV64", "url": "https://www.uniprot.org/uniprotkb/Q6VV64" } ], "reference": [ { "type": "PubMed", "id": "34702947", "url": "https://glygen.org/publication/PubMed/34702947" } ] } ], "crossref": [ { "id": "Q6VV64", "url": "https://www.uniprot.org/uniprotkb/Q6VV64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17962323", "url": "https://glygen.org/publication/PubMed/17962323", "database": "PubMed", "categories": [ "Other" ] }, { "id": "34702947", "url": "https://glygen.org/publication/PubMed/34702947", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "G", "start_aa": "G", "up_seq": "ELGFEDAFYFCFVTLTTIGF", "down_seq": "DIVLVHPHFFLFFSIYIIVG", "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "R", "comment": "Loss of channel conductance. In DRG sensory neurons, results in decreased rheobase current, decreased action potential duration and amplitude upon hyperpolarization and increased sensitivity to depolarizing stimuli, but has no effect on resting membrane potential. Mice carrying the mutant allele display impaired thymic Treg development and increased susceptibility to autoimmune encephalomyelitis.", "evidence": [ { "database": "UniProtKB", "id": "Q6VV64", "url": "https://www.uniprot.org/uniprotkb/Q6VV64" }, { "database": "PubMed", "id": "17962323", "url": "https://glygen.org/publication/PubMed/17962323" }, { "database": "PubMed", "id": "34702947", "url": "https://glygen.org/publication/PubMed/34702947" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "83", "end_pos": "83" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "131", "end_pos": "131" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "264", "end_pos": "264" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "83", "end_pos": "83" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "264", "end_pos": "264" }, { "start_pos": "276", "end_pos": "276" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8R071-1.349.349", "start_pos": 349, "end_pos": 349, "uniprot_canonical_ac": "Q8R071-1", "length": 459, "uniprot_id": "IP3KA_MOUSE", "protein_name": "Inositol-trisphosphate 3-kinase A", "refseq_ac": "NP_666237", "refseq_name": "inositol-trisphosphate 3-kinase A", "gene_name": "Itpka", "gene_names_uniprotkb": "Itpka", "gene_names_refseq": "Itpka", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8R071", "url": "https://www.uniprot.org/uniprotkb/Q8R071" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Increased glucose metabolism in TAMs fuels O-GlcNAcylation of lysosomal Cathepsin B to promote cancer metastasis and chemoresistance.", "journal": "Cancer cell", "date": "2022-10-10", "authors": "Shi Qingzhu, Shen Qicong, Liu Yanfang, Shi Yang, Huang Wenwen, Wang Xi, Li Zhiqing, Chai Yangyang, Wang Hao, Hu Xiangjia, Li Nan, Zhang Qian, Cao Xuetao", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8R071", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8R071" }, { "database": "O-GlcNAc Atlas", "id": "Q8R071", "url": "https://oglcnac.org/atlas/detail/Q8R071" } ], "reference": [ { "type": "PubMed", "id": "36084651", "url": "https://glygen.org/publication/PubMed/36084651" } ] } ], "crossref": [ { "id": "36084651", "url": "https://glygen.org/publication/PubMed/36084651", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8R071", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8R071", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "Q8R071", "url": "https://oglcnac.org/atlas/detail/Q8R071", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RIEGIKKADGSCSTDFKTTR", "down_seq": "REQVTRVFEEFMQGDAEVLR", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser349", "evidence": [ { "id": "36084651", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36084651" }, { "id": "Q8R071", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8R071" }, { "id": "Q8R071", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8R071" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "349", "end_pos": "349" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "195", "end_pos": "195" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8R071-1.135.135", "start_pos": 135, "end_pos": 135, "uniprot_canonical_ac": "Q8R071-1", "length": 459, "uniprot_id": "IP3KA_MOUSE", "protein_name": "Inositol-trisphosphate 3-kinase A", "refseq_ac": "NP_666237", "refseq_name": "inositol-trisphosphate 3-kinase A", "gene_name": "Itpka", "gene_names_uniprotkb": "Itpka", "gene_names_refseq": "Itpka", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8R071", "url": "https://www.uniprot.org/uniprotkb/Q8R071" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8R071", "url": "https://www.uniprot.org/uniprotkb/Q8R071" }, { "database": "iPTMnet", "id": "Q8R071", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8R071" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q8R071", "url": "https://www.uniprot.org/uniprotkb/Q8R071", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8R071", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8R071", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PRRLSTSSLSSTGSSSLLED", "down_seq": "EDDLLSDSESRSRGNVQLET", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8R071", "url": "https://www.uniprot.org/uniprotkb/Q8R071" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q8R071", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8R071" } ], "site_lbl": "Ser135" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "349", "end_pos": "349" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "195", "end_pos": "195" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8R071-1.195.195", "start_pos": 195, "end_pos": 195, "uniprot_canonical_ac": "Q8R071-1", "length": 459, "uniprot_id": "IP3KA_MOUSE", "protein_name": "Inositol-trisphosphate 3-kinase A", "refseq_ac": "NP_666237", "refseq_name": "inositol-trisphosphate 3-kinase A", "gene_name": "Itpka", "gene_names_uniprotkb": "Itpka", "gene_names_refseq": "Itpka", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8R071", "url": "https://www.uniprot.org/uniprotkb/Q8R071" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8R071", "url": "https://www.uniprot.org/uniprotkb/Q8R071", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PVMSPFRKRYSWVQLAGHTG", "down_seq": "FKAAGTSGLILKRSSEPEHY", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8R071", "url": "https://www.uniprot.org/uniprotkb/Q8R071" } ], "site_lbl": "Ser195" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "349", "end_pos": "349" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "195", "end_pos": "195" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8R0A7-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "Q8R0A7-1", "length": 407, "uniprot_id": "K0513_MOUSE", "protein_name": "Uncharacterized protein KIAA0513", "refseq_ac": "NP_001157232", "refseq_name": "uncharacterized protein KIAA0513 isoform a", "gene_name": "6430548M08Rik; Kiaa0513", "gene_names_uniprotkb": "6430548M08Rik; Kiaa0513", "gene_names_refseq": "6430548M08Rik; Kiaa0513; mKIAA0513", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8R0A7", "url": "https://www.uniprot.org/uniprotkb/Q8R0A7" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8R0A7", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8R0A7" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] } ], "crossref": [ { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8R0A7", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8R0A7", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" }, { "id": "Q8R0A7", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8R0A7" } ] } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "275", "end_pos": "275" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8R0A7-1.275.275", "start_pos": 275, "end_pos": 275, "uniprot_canonical_ac": "Q8R0A7-1", "length": 407, "uniprot_id": "K0513_MOUSE", "protein_name": "Uncharacterized protein KIAA0513", "refseq_ac": "NP_001157232", "refseq_name": "uncharacterized protein KIAA0513 isoform a", "gene_name": "6430548M08Rik; Kiaa0513", "gene_names_uniprotkb": "6430548M08Rik; Kiaa0513", "gene_names_refseq": "6430548M08Rik; Kiaa0513; mKIAA0513", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8R0A7", "url": "https://www.uniprot.org/uniprotkb/Q8R0A7" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8R0A7", "url": "https://www.uniprot.org/uniprotkb/Q8R0A7" }, { "database": "iPTMnet", "id": "Q8R0A7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8R0A7" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q8R0A7", "url": "https://www.uniprot.org/uniprotkb/Q8R0A7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8R0A7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8R0A7", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KNEEDENKPKDRQTKTVTMI", "down_seq": "PEDEQKGEKVYLYTHLRQQP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8R0A7", "url": "https://www.uniprot.org/uniprotkb/Q8R0A7" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q8R0A7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8R0A7" } ], "site_lbl": "Ser275" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "275", "end_pos": "275" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9EQF4-1.185.185", "start_pos": 185, "end_pos": 185, "uniprot_canonical_ac": "Q9EQF4-1", "length": 244, "uniprot_id": "JUNO_MOUSE", "protein_name": "Sperm-egg fusion protein Juno", "refseq_ac": "NP_075026", "refseq_name": "sperm-egg fusion protein Juno isoform 1 precursor", "gene_name": "Izumo1r", "gene_names_uniprotkb": "Izumo1r; Folbp3; Folr4; Juno", "gene_names_refseq": "0910001L11Rik; Folbp3; Folr4; Izumo1r; Juno", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9EQF4", "url": "https://www.uniprot.org/uniprotkb/Q9EQF4" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Divergent evolution of vitamin B9 binding underlies Juno-mediated adhesion of mammalian gametes.", "journal": "Current biology : CB", "date": "2016", "authors": "Han L, Nishimura K, Sadat Al Hosseini H, Bianchi E, Wright GJ, Jovine L", "evidence": [ { "database": "UniProtKB", "id": "Q9EQF4", "url": "https://www.uniprot.org/uniprotkb/Q9EQF4#ptm_processing" }, { "database": "UniProtKB", "id": "Q9EQF4", "url": "https://www.uniprot.org/uniprotkb/Q9EQF4" } ], "reference": [ { "type": "PubMed", "id": "26859261", "url": "https://glygen.org/publication/PubMed/26859261" } ] }, { "title": "Structural and functional insights into IZUMO1 recognition by JUNO in mammalian fertilization.", "journal": "Nature communications", "date": "2016", "authors": "Kato K, Satouh Y, Nishimasu H, Kurabayashi A, Morita J, Fujihara Y, Oji A, Ishitani R, Ikawa M, Nureki O", "evidence": [ { "database": "UniProtKB", "id": "Q9EQF4", "url": "https://www.uniprot.org/uniprotkb/Q9EQF4#ptm_processing" }, { "database": "UniProtKB", "id": "Q9EQF4", "url": "https://www.uniprot.org/uniprotkb/Q9EQF4" } ], "reference": [ { "type": "PubMed", "id": "27416963", "url": "https://glygen.org/publication/PubMed/27416963" } ] } ], "crossref": [ { "id": "Q9EQF4", "url": "https://www.uniprot.org/uniprotkb/Q9EQF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "26859261", "url": "https://glygen.org/publication/PubMed/26859261", "database": "PubMed", "categories": [ "Other" ] }, { "id": "5EJN", "url": "https://www.rcsb.org/structure/5EJN", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "27416963", "url": "https://glygen.org/publication/PubMed/27416963", "database": "PubMed", "categories": [ "Other" ] }, { "id": "5JYJ", "url": "https://www.rcsb.org/structure/5JYJ", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "5EJN|B|185", "url": "", "database": "", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "PCLPFSYHFPTPDDLCEKIW", "down_seq": "NTFKASPERRNSGRCLQKWF", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": { "label": "iCn3D", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?bcifid=5EJN&bu=0&command=select+.B:185;+center+selection;+zoom+selection" }, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn185", "evidence": [ { "id": "Q9EQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9EQF4#ptm_processing" }, { "id": "26859261", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/26859261" }, { "id": "5EJN", "database": "PDB", "url": "https://www.rcsb.org/sequence/5EJN" }, { "id": "27416963", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/27416963" }, { "id": "5JYJ", "database": "PDB", "url": "https://www.rcsb.org/sequence/5JYJ" } ] } ], "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "D", "comment": "Reduced stability of the protein.", "evidence": [ { "database": "UniProtKB", "id": "Q9EQF4", "url": "https://www.uniprot.org/uniprotkb/Q9EQF4" }, { "database": "PubMed", "id": "27416963", "url": "https://glygen.org/publication/PubMed/27416963" } ] }, { "sequence_org": "N", "sequence_mut": "G", "comment": "Reduces apparent molecular weight of the protein, in agreement with the loss of one glycosylation site. Abolishes secretion of the extracellular domain; when associated with Q-73.", "evidence": [ { "database": "UniProtKB", "id": "Q9EQF4", "url": "https://www.uniprot.org/uniprotkb/Q9EQF4" }, { "database": "PubMed", "id": "26859261", "url": "https://glygen.org/publication/PubMed/26859261" } ] }, { "sequence_org": "N", "sequence_mut": "S", "comment": "No effect on interaction with IZUMO1.", "evidence": [ { "database": "UniProtKB", "id": "Q9EQF4", "url": "https://www.uniprot.org/uniprotkb/Q9EQF4" }, { "database": "PubMed", "id": "26859261", "url": "https://glygen.org/publication/PubMed/26859261" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "185", "end_pos": "185" }, { "start_pos": "73", "end_pos": "73" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "97", "end_pos": "97" } ] }, { "type": "snv", "site_list": [ { "start_pos": "25", "end_pos": "25" } ] } ], "categories": [ "glycosylation_flag", "mutagenesis_flag" ], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "Q9EQF4-1.184.184", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "icn3d_view.label", "icn3d_view.url", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "icn3d_view.label", "icn3d_view.url", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9EQF4-1.73.73", "start_pos": 73, "end_pos": 73, "uniprot_canonical_ac": "Q9EQF4-1", "length": 244, "uniprot_id": "JUNO_MOUSE", "protein_name": "Sperm-egg fusion protein Juno", "refseq_ac": "NP_075026", "refseq_name": "sperm-egg fusion protein Juno isoform 1 precursor", "gene_name": "Izumo1r", "gene_names_uniprotkb": "Izumo1r; Folbp3; Folr4; Juno", "gene_names_refseq": "0910001L11Rik; Folbp3; Folr4; Izumo1r; Juno", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9EQF4", "url": "https://www.uniprot.org/uniprotkb/Q9EQF4" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Divergent evolution of vitamin B9 binding underlies Juno-mediated adhesion of mammalian gametes.", "journal": "Current biology : CB", "date": "2016", "authors": "Han L, Nishimura K, Sadat Al Hosseini H, Bianchi E, Wright GJ, Jovine L", "evidence": [ { "database": "UniProtKB", "id": "Q9EQF4", "url": "https://www.uniprot.org/uniprotkb/Q9EQF4#ptm_processing" }, { "database": "UniProtKB", "id": "Q9EQF4", "url": "https://www.uniprot.org/uniprotkb/Q9EQF4" } ], "reference": [ { "type": "PubMed", "id": "26859261", "url": "https://glygen.org/publication/PubMed/26859261" } ] }, { "title": "Structural and functional insights into IZUMO1 recognition by JUNO in mammalian fertilization.", "journal": "Nature communications", "date": "2016", "authors": "Kato K, Satouh Y, Nishimasu H, Kurabayashi A, Morita J, Fujihara Y, Oji A, Ishitani R, Ikawa M, Nureki O", "evidence": [ { "database": "UniProtKB", "id": "Q9EQF4", "url": "https://www.uniprot.org/uniprotkb/Q9EQF4#ptm_processing" }, { "database": "UniProtKB", "id": "Q9EQF4", "url": "https://www.uniprot.org/uniprotkb/Q9EQF4" } ], "reference": [ { "type": "PubMed", "id": "27416963", "url": "https://glygen.org/publication/PubMed/27416963" } ] } ], "crossref": [ { "id": "Q9EQF4", "url": "https://www.uniprot.org/uniprotkb/Q9EQF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "26859261", "url": "https://glygen.org/publication/PubMed/26859261", "database": "PubMed", "categories": [ "Other" ] }, { "id": "27416963", "url": "https://glygen.org/publication/PubMed/27416963", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "NACCTRSTSWEAHLEEPLLF", "down_seq": "FSMMHCGLLTPACRKHFIQA", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn73", "evidence": [ { "id": "Q9EQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9EQF4#ptm_processing" }, { "id": "26859261", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/26859261" } ] } ], "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "D", "comment": "Does not affect ability to promote sperm-egg interaction.", "evidence": [ { "database": "UniProtKB", "id": "Q9EQF4", "url": "https://www.uniprot.org/uniprotkb/Q9EQF4" }, { "database": "PubMed", "id": "27416963", "url": "https://glygen.org/publication/PubMed/27416963" } ] }, { "sequence_org": "N", "sequence_mut": "Q", "comment": "Reduces apparent molecular weight of the protein, in agreement with the loss of one glycosylation site. Abolishes secretion of the extracellular domain; when associated with G-185.", "evidence": [ { "database": "UniProtKB", "id": "Q9EQF4", "url": "https://www.uniprot.org/uniprotkb/Q9EQF4" }, { "database": "PubMed", "id": "26859261", "url": "https://glygen.org/publication/PubMed/26859261" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "185", "end_pos": "185" }, { "start_pos": "73", "end_pos": "73" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "97", "end_pos": "97" } ] }, { "type": "snv", "site_list": [ { "start_pos": "25", "end_pos": "25" } ] } ], "categories": [ "glycosylation_flag", "mutagenesis_flag" ], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "Q9EQF4-1.62.62", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "downstream", "id": "Q9EQF4-1.66.66", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9EQF4-1.184.184", "start_pos": 184, "end_pos": 184, "uniprot_canonical_ac": "Q9EQF4-1", "length": 244, "uniprot_id": "JUNO_MOUSE", "protein_name": "Sperm-egg fusion protein Juno", "refseq_ac": "NP_075026", "refseq_name": "sperm-egg fusion protein Juno isoform 1 precursor", "gene_name": "Izumo1r", "gene_names_uniprotkb": "Izumo1r; Folbp3; Folr4; Juno", "gene_names_refseq": "0910001L11Rik; Folbp3; Folr4; Izumo1r; Juno", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9EQF4", "url": "https://www.uniprot.org/uniprotkb/Q9EQF4" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Structural and functional insights into IZUMO1 recognition by JUNO in mammalian fertilization.", "journal": "Nature communications", "date": "2016", "authors": "Kato K, Satouh Y, Nishimasu H, Kurabayashi A, Morita J, Fujihara Y, Oji A, Ishitani R, Ikawa M, Nureki O", "evidence": [ { "database": "UniProtKB", "id": "Q9EQF4", "url": "https://www.uniprot.org/uniprotkb/Q9EQF4#ptm_processing" }, { "database": "UniProtKB", "id": "Q9EQF4", "url": "https://www.uniprot.org/uniprotkb/Q9EQF4" } ], "reference": [ { "type": "PubMed", "id": "27416963", "url": "https://glygen.org/publication/PubMed/27416963" } ] } ], "crossref": [ { "id": "Q9EQF4", "url": "https://www.uniprot.org/uniprotkb/Q9EQF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "27416963", "url": "https://glygen.org/publication/PubMed/27416963", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "W", "start_aa": "W", "up_seq": "EPCLPFSYHFPTPDDLCEKI", "down_seq": "NNTFKASPERRNSGRCLQKW", "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "A", "comment": "Does not affect ability to promote sperm-egg interaction.", "evidence": [ { "database": "UniProtKB", "id": "Q9EQF4", "url": "https://www.uniprot.org/uniprotkb/Q9EQF4" }, { "database": "PubMed", "id": "27416963", "url": "https://glygen.org/publication/PubMed/27416963" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "185", "end_pos": "185" }, { "start_pos": "73", "end_pos": "73" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "97", "end_pos": "97" } ] }, { "type": "snv", "site_list": [ { "start_pos": "25", "end_pos": "25" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "Q9EQF4-1.185.185", "categories": [ "glycosylation_flag", "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9EQF4-1.62.62", "start_pos": 62, "end_pos": 62, "uniprot_canonical_ac": "Q9EQF4-1", "length": 244, "uniprot_id": "JUNO_MOUSE", "protein_name": "Sperm-egg fusion protein Juno", "refseq_ac": "NP_075026", "refseq_name": "sperm-egg fusion protein Juno isoform 1 precursor", "gene_name": "Izumo1r", "gene_names_uniprotkb": "Izumo1r; Folbp3; Folr4; Juno", "gene_names_refseq": "0910001L11Rik; Folbp3; Folr4; Izumo1r; Juno", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9EQF4", "url": "https://www.uniprot.org/uniprotkb/Q9EQF4" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Structural and functional insights into IZUMO1 recognition by JUNO in mammalian fertilization.", "journal": "Nature communications", "date": "2016", "authors": "Kato K, Satouh Y, Nishimasu H, Kurabayashi A, Morita J, Fujihara Y, Oji A, Ishitani R, Ikawa M, Nureki O", "evidence": [ { "database": "UniProtKB", "id": "Q9EQF4", "url": "https://www.uniprot.org/uniprotkb/Q9EQF4#ptm_processing" }, { "database": "UniProtKB", "id": "Q9EQF4", "url": "https://www.uniprot.org/uniprotkb/Q9EQF4" } ], "reference": [ { "type": "PubMed", "id": "27416963", "url": "https://glygen.org/publication/PubMed/27416963" } ] } ], "crossref": [ { "id": "Q9EQF4", "url": "https://www.uniprot.org/uniprotkb/Q9EQF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "27416963", "url": "https://glygen.org/publication/PubMed/27416963", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "W", "start_aa": "W", "up_seq": "ELYQECRPWEDNACCTRSTS", "down_seq": "EAHLEEPLLFNFSMMHCGLL", "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "A", "comment": "Impaired ability to promote sperm-egg interaction due to reduced interaction with IZUMO1.", "evidence": [ { "database": "UniProtKB", "id": "Q9EQF4", "url": "https://www.uniprot.org/uniprotkb/Q9EQF4" }, { "database": "PubMed", "id": "27416963", "url": "https://glygen.org/publication/PubMed/27416963" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "185", "end_pos": "185" }, { "start_pos": "73", "end_pos": "73" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "97", "end_pos": "97" } ] }, { "type": "snv", "site_list": [ { "start_pos": "25", "end_pos": "25" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "Q9EQF4-1.66.66", "categories": [ "mutagenesis_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q9EQF4-1.73.73", "categories": [ "glycosylation_flag", "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9EQF4-1.66.66", "start_pos": 66, "end_pos": 66, "uniprot_canonical_ac": "Q9EQF4-1", "length": 244, "uniprot_id": "JUNO_MOUSE", "protein_name": "Sperm-egg fusion protein Juno", "refseq_ac": "NP_075026", "refseq_name": "sperm-egg fusion protein Juno isoform 1 precursor", "gene_name": "Izumo1r", "gene_names_uniprotkb": "Izumo1r; Folbp3; Folr4; Juno", "gene_names_refseq": "0910001L11Rik; Folbp3; Folr4; Izumo1r; Juno", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9EQF4", "url": "https://www.uniprot.org/uniprotkb/Q9EQF4" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Structural and functional insights into IZUMO1 recognition by JUNO in mammalian fertilization.", "journal": "Nature communications", "date": "2016", "authors": "Kato K, Satouh Y, Nishimasu H, Kurabayashi A, Morita J, Fujihara Y, Oji A, Ishitani R, Ikawa M, Nureki O", "evidence": [ { "database": "UniProtKB", "id": "Q9EQF4", "url": "https://www.uniprot.org/uniprotkb/Q9EQF4#ptm_processing" }, { "database": "UniProtKB", "id": "Q9EQF4", "url": "https://www.uniprot.org/uniprotkb/Q9EQF4" } ], "reference": [ { "type": "PubMed", "id": "27416963", "url": "https://glygen.org/publication/PubMed/27416963" } ] } ], "crossref": [ { "id": "Q9EQF4", "url": "https://www.uniprot.org/uniprotkb/Q9EQF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "27416963", "url": "https://glygen.org/publication/PubMed/27416963", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "L", "start_aa": "L", "up_seq": "ECRPWEDNACCTRSTSWEAH", "down_seq": "EEPLLFNFSMMHCGLLTPAC", "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "A", "comment": "Does not affect ability to promote sperm-egg interaction.", "evidence": [ { "database": "UniProtKB", "id": "Q9EQF4", "url": "https://www.uniprot.org/uniprotkb/Q9EQF4" }, { "database": "PubMed", "id": "27416963", "url": "https://glygen.org/publication/PubMed/27416963" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "185", "end_pos": "185" }, { "start_pos": "73", "end_pos": "73" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "97", "end_pos": "97" } ] }, { "type": "snv", "site_list": [ { "start_pos": "25", "end_pos": "25" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "Q9EQF4-1.62.62", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q9EQF4-1.73.73", "categories": [ "glycosylation_flag", "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9EQF4-1.97.97", "start_pos": 97, "end_pos": 97, "uniprot_canonical_ac": "Q9EQF4-1", "length": 244, "uniprot_id": "JUNO_MOUSE", "protein_name": "Sperm-egg fusion protein Juno", "refseq_ac": "NP_075026", "refseq_name": "sperm-egg fusion protein Juno isoform 1 precursor", "gene_name": "Izumo1r", "gene_names_uniprotkb": "Izumo1r; Folbp3; Folr4; Juno", "gene_names_refseq": "0910001L11Rik; Folbp3; Folr4; Izumo1r; Juno", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9EQF4", "url": "https://www.uniprot.org/uniprotkb/Q9EQF4" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Structural and functional insights into IZUMO1 recognition by JUNO in mammalian fertilization.", "journal": "Nature communications", "date": "2016", "authors": "Kato K, Satouh Y, Nishimasu H, Kurabayashi A, Morita J, Fujihara Y, Oji A, Ishitani R, Ikawa M, Nureki O", "evidence": [ { "database": "UniProtKB", "id": "Q9EQF4", "url": "https://www.uniprot.org/uniprotkb/Q9EQF4#ptm_processing" }, { "database": "UniProtKB", "id": "Q9EQF4", "url": "https://www.uniprot.org/uniprotkb/Q9EQF4" } ], "reference": [ { "type": "PubMed", "id": "27416963", "url": "https://glygen.org/publication/PubMed/27416963" } ] } ], "crossref": [ { "id": "Q9EQF4", "url": "https://www.uniprot.org/uniprotkb/Q9EQF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "27416963", "url": "https://glygen.org/publication/PubMed/27416963", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "H", "start_aa": "H", "up_seq": "MHCGLLTPACRKHFIQAICF", "down_seq": "ECSPNLGPWIQPVVPNGQEE", "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Does not affect ability to promote sperm-egg interaction.", "evidence": [ { "database": "UniProtKB", "id": "Q9EQF4", "url": "https://www.uniprot.org/uniprotkb/Q9EQF4" }, { "database": "PubMed", "id": "27416963", "url": "https://glygen.org/publication/PubMed/27416963" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "185", "end_pos": "185" }, { "start_pos": "73", "end_pos": "73" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "97", "end_pos": "97" } ] }, { "type": "snv", "site_list": [ { "start_pos": "25", "end_pos": "25" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9EQF4-1.25.25", "start_pos": 25, "end_pos": 25, "uniprot_canonical_ac": "Q9EQF4-1", "length": 244, "uniprot_id": "JUNO_MOUSE", "protein_name": "Sperm-egg fusion protein Juno", "refseq_ac": "NP_075026", "refseq_name": "sperm-egg fusion protein Juno isoform 1 precursor", "gene_name": "Izumo1r", "gene_names_uniprotkb": "Izumo1r; Folbp3; Folr4; Juno", "gene_names_refseq": "0910001L11Rik; Folbp3; Folr4; Izumo1r; Juno", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9EQF4", "url": "https://www.uniprot.org/uniprotkb/Q9EQF4" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs218511939", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs218511939", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "WQILLGLWAVLPTLAGDKLL", "down_seq": "VCMNSKRHKQEPGPEDELYQ", "snv": [ { "evidence": [ { "id": "rs218511939", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs218511939" } ], "glycoeffect": [ "n-glyco-sequon-gain", "o-glyco-site-loss" ], "sequence_org": "S", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (SVC->NVC).", "chr_id": "9", "chr_pos": "14813743", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S25", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "185", "end_pos": "185" }, { "start_pos": "73", "end_pos": "73" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "97", "end_pos": "97" } ] }, { "type": "snv", "site_list": [ { "start_pos": "25", "end_pos": "25" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9ET78-1.483.483", "start_pos": 483, "end_pos": 483, "uniprot_canonical_ac": "Q9ET78-1", "length": 696, "uniprot_id": "JPH2_MOUSE", "protein_name": "Junctophilin-2", "refseq_ac": "NP_001192005", "refseq_name": "junctophilin-2", "gene_name": "Jph2", "gene_names_uniprotkb": "Jph2; Jp2", "gene_names_refseq": "1110002E14Rik; JP-2; Jp2; Jph2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78" }, { "database": "iPTMnet", "id": "Q9ET78", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ET78" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9ET78", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ET78", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "PQLHERETPQPEGGPPSPAG", "down_seq": "PPQPKRPRPGASKDGLLSPG", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr483", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q9ET78", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ET78" } ], "site_lbl": "Thr483" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "483", "end_pos": "483" }, { "start_pos": "518", "end_pos": "518" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "153", "end_pos": "158" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "488", "end_pos": "492" }, { "start_pos": "563", "end_pos": "568" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "162", "end_pos": "162" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "613", "end_pos": "613" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "Q9ET78-1.470.470", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q9ET78-1.479.479", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q9ET78-1.488.492", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9ET78-1.518.518", "start_pos": 518, "end_pos": 518, "uniprot_canonical_ac": "Q9ET78-1", "length": 696, "uniprot_id": "JPH2_MOUSE", "protein_name": "Junctophilin-2", "refseq_ac": "NP_001192005", "refseq_name": "junctophilin-2", "gene_name": "Jph2", "gene_names_uniprotkb": "Jph2; Jp2", "gene_names_refseq": "1110002E14Rik; JP-2; Jp2; Jph2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "GLLSPGSWNGEPGGEGSRPA", "down_seq": "PSDGAGRRSPARPASEHMAI", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr518", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "483", "end_pos": "483" }, { "start_pos": "518", "end_pos": "518" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "153", "end_pos": "158" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "488", "end_pos": "492" }, { "start_pos": "563", "end_pos": "568" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "162", "end_pos": "162" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "613", "end_pos": "613" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "upstream", "id": "Q9ET78-1.527.527", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q9ET78-1.533.533", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9ET78-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "Q9ET78-1", "length": 696, "uniprot_id": "JPH2_MOUSE", "protein_name": "Junctophilin-2", "refseq_ac": "NP_001192005", "refseq_name": "junctophilin-2", "gene_name": "Jph2", "gene_names_uniprotkb": "Jph2; Jp2", "gene_names_refseq": "1110002E14Rik; JP-2; Jp2; Jph2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A reference dataset of O-GlcNAc proteins in quadriceps skeletal muscle from mice.", "journal": "Glycobiology", "date": "2025-02-10", "authors": "Jaiswal Ruchi, Liu Yimin, Petriello Michael, Zhang Xiangmin, Yi Zhengping, Fehl Charlie", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9ET78", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9ET78" } ], "reference": [ { "type": "PubMed", "id": "39927985", "url": "https://glygen.org/publication/PubMed/39927985" } ] }, { "title": "First comprehensive identification of cardiac proteins with putative increased O-GlcNAc levels during pressure overload hypertrophy.", "journal": "PloS one", "date": "2022", "authors": "Zhu Wei Zhong, Palazzo Teresa, Zhou Mowei, Ledee Dolena, Olson Heather M, Pa\u0161a-Toli\u0107 Ljiljana, Olson Aaron K", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9ET78", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9ET78" } ], "reference": [ { "type": "PubMed", "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343" } ] } ], "crossref": [ { "id": "39927985", "url": "https://glygen.org/publication/PubMed/39927985", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9ET78", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9ET78", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343", "database": "PubMed", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "39927985", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39927985" }, { "id": "Q9ET78", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9ET78" }, { "id": "36288343", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36288343" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "483", "end_pos": "483" }, { "start_pos": "518", "end_pos": "518" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "153", "end_pos": "158" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "488", "end_pos": "492" }, { "start_pos": "563", "end_pos": "568" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "162", "end_pos": "162" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "613", "end_pos": "613" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9ET78-1.153.158", "start_pos": 153, "end_pos": 158, "uniprot_canonical_ac": "Q9ET78-1", "length": 696, "uniprot_id": "JPH2_MOUSE", "protein_name": "Junctophilin-2", "refseq_ac": "NP_001192005", "refseq_name": "junctophilin-2", "gene_name": "Jph2", "gene_names_uniprotkb": "Jph2; Jp2", "gene_names_refseq": "1110002E14Rik; JP-2; Jp2; Jph2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Molecular Determinants of Calpain-dependent Cleavage of Junctophilin-2 Protein in Cardiomyocytes.", "journal": "The Journal of biological chemistry", "date": "2015", "authors": "Guo A, Hall D, Zhang C, Peng T, Miller JD, Kutschke W, Grueter CE, Johnson FL, Lin RZ, Song LS", "evidence": [ { "database": "UniProtKB", "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78" } ], "reference": [ { "type": "PubMed", "id": "26063807", "url": "https://glygen.org/publication/PubMed/26063807" } ] } ], "crossref": [ { "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "26063807", "url": "https://glygen.org/publication/PubMed/26063807", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "VVVRSP", "start_aa": "V", "up_seq": "FTNGMRHGYGVRQSVPYGMA", "down_seq": "LRTSLSSLRSEHSNGTVAPD", "mutagenesis": [ { "sequence_org": "VVVRSP", "sequence_mut": "", "comment": "Abolishes cleavage by calpain at the N-terminus.", "evidence": [ { "database": "UniProtKB", "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78" }, { "database": "PubMed", "id": "26063807", "url": "https://glygen.org/publication/PubMed/26063807" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "483", "end_pos": "483" }, { "start_pos": "518", "end_pos": "518" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "153", "end_pos": "158" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "488", "end_pos": "492" }, { "start_pos": "563", "end_pos": "568" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "162", "end_pos": "162" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "613", "end_pos": "613" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "Q9ET78-1.162.162", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q9ET78-1.165.165", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9ET78-1.399.399", "start_pos": 399, "end_pos": 399, "uniprot_canonical_ac": "Q9ET78-1", "length": 696, "uniprot_id": "JPH2_MOUSE", "protein_name": "Junctophilin-2", "refseq_ac": "NP_001192005", "refseq_name": "junctophilin-2", "gene_name": "Jph2", "gene_names_uniprotkb": "Jph2; Jp2", "gene_names_refseq": "1110002E14Rik; JP-2; Jp2; Jph2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Novel junctophilin-2 mutation A405S is associated with basal septal hypertrophy and diastolic dysfunction.", "journal": "JACC. Basic to translational science", "date": "2017", "authors": "Quick AP, Landstrom AP, Wang Q, Beavers DL, Reynolds JO, Barreto-Torres G, Tran V, Showell J, Philippen LE, Morris SA, Skapura D, Bos JM, Pedersen SE, Pautler RG, Ackerman MJ, Wehrens XH", "evidence": [ { "database": "UniProtKB", "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78" } ], "reference": [ { "type": "PubMed", "id": "28393127", "url": "https://glygen.org/publication/PubMed/28393127" } ] } ], "crossref": [ { "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "28393127", "url": "https://glygen.org/publication/PubMed/28393127", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "A", "start_aa": "A", "up_seq": "EIAASRTSHAKAKAEAAEQA", "down_seq": "LAANQESNIARTLAKELAPD", "mutagenesis": [ { "sequence_org": "A", "sequence_mut": "S", "comment": "Decreased transverse tubule regularity and aberrant calcium handling in septal cardiomyocytes.", "evidence": [ { "database": "UniProtKB", "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78" }, { "database": "PubMed", "id": "28393127", "url": "https://glygen.org/publication/PubMed/28393127" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "483", "end_pos": "483" }, { "start_pos": "518", "end_pos": "518" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "153", "end_pos": "158" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "488", "end_pos": "492" }, { "start_pos": "563", "end_pos": "568" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "162", "end_pos": "162" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "613", "end_pos": "613" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9ET78-1.488.492", "start_pos": 488, "end_pos": 492, "uniprot_canonical_ac": "Q9ET78-1", "length": 696, "uniprot_id": "JPH2_MOUSE", "protein_name": "Junctophilin-2", "refseq_ac": "NP_001192005", "refseq_name": "junctophilin-2", "gene_name": "Jph2", "gene_names_uniprotkb": "Jph2; Jp2", "gene_names_refseq": "1110002E14Rik; JP-2; Jp2; Jph2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "E-C coupling structural protein junctophilin-2 encodes a stress-adaptive transcription regulator.", "journal": "Science (New York, N.Y.)", "date": "2018", "authors": "Guo A, Wang Y, Chen B, Wang Y, Yuan J, Zhang L, Hall D, Wu J, Shi Y, Zhu Q, Chen C, Thiel WH, Zhan X, Weiss RM, Zhan F, Musselman CA, Pufall M, Zhu W, Au KF, Hong J, Anderson ME, Grueter CE, Song LS", "evidence": [ { "database": "UniProtKB", "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78" } ], "reference": [ { "type": "PubMed", "id": "30409805", "url": "https://glygen.org/publication/PubMed/30409805" } ] } ], "crossref": [ { "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "30409805", "url": "https://glygen.org/publication/PubMed/30409805", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "KRPRP", "start_aa": "K", "up_seq": "RETPQPEGGPPSPAGTPPQP", "down_seq": "GASKDGLLSPGSWNGEPGGE", "mutagenesis": [ { "sequence_org": "KRPRP", "sequence_mut": "", "comment": "Abolishes nuclear localization of the Junctophilin-2 N-terminal fragment chain.", "evidence": [ { "database": "UniProtKB", "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78" }, { "database": "PubMed", "id": "30409805", "url": "https://glygen.org/publication/PubMed/30409805" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "483", "end_pos": "483" }, { "start_pos": "518", "end_pos": "518" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "153", "end_pos": "158" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "488", "end_pos": "492" }, { "start_pos": "563", "end_pos": "568" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "162", "end_pos": "162" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "613", "end_pos": "613" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "Q9ET78-1.470.470", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "Q9ET78-1.479.479", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q9ET78-1.483.483", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9ET78-1.563.568", "start_pos": 563, "end_pos": 568, "uniprot_canonical_ac": "Q9ET78-1", "length": 696, "uniprot_id": "JPH2_MOUSE", "protein_name": "Junctophilin-2", "refseq_ac": "NP_001192005", "refseq_name": "junctophilin-2", "gene_name": "Jph2", "gene_names_uniprotkb": "Jph2; Jp2", "gene_names_refseq": "1110002E14Rik; JP-2; Jp2; Jph2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Molecular Determinants of Calpain-dependent Cleavage of Junctophilin-2 Protein in Cardiomyocytes.", "journal": "The Journal of biological chemistry", "date": "2015", "authors": "Guo A, Hall D, Zhang C, Peng T, Miller JD, Kutschke W, Grueter CE, Johnson FL, Lin RZ, Song LS", "evidence": [ { "database": "UniProtKB", "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78" } ], "reference": [ { "type": "PubMed", "id": "26063807", "url": "https://glygen.org/publication/PubMed/26063807" } ] } ], "crossref": [ { "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "26063807", "url": "https://glygen.org/publication/PubMed/26063807", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "AVRTGP", "start_aa": "A", "up_seq": "PPPAPSQEPEVAMYRGYHSY", "down_seq": "PEPPPLEDEQEPEPEPEPEV", "mutagenesis": [ { "sequence_org": "AVRTGP", "sequence_mut": "", "comment": "Abolishes cleavage by calpain at the C-terminus.", "evidence": [ { "database": "UniProtKB", "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78" }, { "database": "PubMed", "id": "26063807", "url": "https://glygen.org/publication/PubMed/26063807" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "483", "end_pos": "483" }, { "start_pos": "518", "end_pos": "518" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "153", "end_pos": "158" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "488", "end_pos": "492" }, { "start_pos": "563", "end_pos": "568" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "162", "end_pos": "162" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "613", "end_pos": "613" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9ET78-1.162.162", "start_pos": 162, "end_pos": 162, "uniprot_canonical_ac": "Q9ET78-1", "length": 696, "uniprot_id": "JPH2_MOUSE", "protein_name": "Junctophilin-2", "refseq_ac": "NP_001192005", "refseq_name": "junctophilin-2", "gene_name": "Jph2", "gene_names_uniprotkb": "Jph2; Jp2", "gene_names_refseq": "1110002E14Rik; JP-2; Jp2; Jph2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GVRQSVPYGMAVVVRSPLRT", "down_seq": "LSSLRSEHSNGTVAPDSPAA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78" } ], "site_lbl": "Ser162" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "483", "end_pos": "483" }, { "start_pos": "518", "end_pos": "518" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "153", "end_pos": "158" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "488", "end_pos": "492" }, { "start_pos": "563", "end_pos": "568" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "162", "end_pos": "162" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "613", "end_pos": "613" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "Q9ET78-1.153.158", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q9ET78-1.165.165", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9ET78-1.165.165", "start_pos": 165, "end_pos": 165, "uniprot_canonical_ac": "Q9ET78-1", "length": 696, "uniprot_id": "JPH2_MOUSE", "protein_name": "Junctophilin-2", "refseq_ac": "NP_001192005", "refseq_name": "junctophilin-2", "gene_name": "Jph2", "gene_names_uniprotkb": "Jph2; Jp2", "gene_names_refseq": "1110002E14Rik; JP-2; Jp2; Jph2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QSVPYGMAVVVRSPLRTSLS", "down_seq": "LRSEHSNGTVAPDSPAADGP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78" } ], "site_lbl": "Ser165" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "483", "end_pos": "483" }, { "start_pos": "518", "end_pos": "518" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "153", "end_pos": "158" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "488", "end_pos": "492" }, { "start_pos": "563", "end_pos": "568" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "162", "end_pos": "162" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "613", "end_pos": "613" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "Q9ET78-1.153.158", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q9ET78-1.162.162", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9ET78-1.440.440", "start_pos": 440, "end_pos": 440, "uniprot_canonical_ac": "Q9ET78-1", "length": 696, "uniprot_id": "JPH2_MOUSE", "protein_name": "Junctophilin-2", "refseq_ac": "NP_001192005", "refseq_name": "junctophilin-2", "gene_name": "Jph2", "gene_names_uniprotkb": "Jph2; Jp2", "gene_names_refseq": "1110002E14Rik; JP-2; Jp2; Jph2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "FYQPGPEYQKRRLLQEILEN", "down_seq": "ESLLEPPERGLGTGLPERPR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78" } ], "site_lbl": "Ser440" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "483", "end_pos": "483" }, { "start_pos": "518", "end_pos": "518" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "153", "end_pos": "158" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "488", "end_pos": "492" }, { "start_pos": "563", "end_pos": "568" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "162", "end_pos": "162" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "613", "end_pos": "613" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "Q9ET78-1.442.442", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9ET78-1.442.442", "start_pos": 442, "end_pos": 442, "uniprot_canonical_ac": "Q9ET78-1", "length": 696, "uniprot_id": "JPH2_MOUSE", "protein_name": "Junctophilin-2", "refseq_ac": "NP_001192005", "refseq_name": "junctophilin-2", "gene_name": "Jph2", "gene_names_uniprotkb": "Jph2; Jp2", "gene_names_refseq": "1110002E14Rik; JP-2; Jp2; Jph2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QPGPEYQKRRLLQEILENSE", "down_seq": "LLEPPERGLGTGLPERPRES", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78" } ], "site_lbl": "Ser442" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "483", "end_pos": "483" }, { "start_pos": "518", "end_pos": "518" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "153", "end_pos": "158" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "488", "end_pos": "492" }, { "start_pos": "563", "end_pos": "568" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "162", "end_pos": "162" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "613", "end_pos": "613" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "Q9ET78-1.440.440", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "Q9ET78-1.462.462", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9ET78-1.462.462", "start_pos": 462, "end_pos": 462, "uniprot_canonical_ac": "Q9ET78-1", "length": 696, "uniprot_id": "JPH2_MOUSE", "protein_name": "Junctophilin-2", "refseq_ac": "NP_001192005", "refseq_name": "junctophilin-2", "gene_name": "Jph2", "gene_names_uniprotkb": "Jph2; Jp2", "gene_names_refseq": "1110002E14Rik; JP-2; Jp2; Jph2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78" }, { "database": "iPTMnet", "id": "Q9ET78", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ET78" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9ET78", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ET78", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SLLEPPERGLGTGLPERPRE", "down_seq": "PQLHERETPQPEGGPPSPAG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q9ET78", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ET78" } ], "site_lbl": "Ser462" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "483", "end_pos": "483" }, { "start_pos": "518", "end_pos": "518" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "153", "end_pos": "158" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "488", "end_pos": "492" }, { "start_pos": "563", "end_pos": "568" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "162", "end_pos": "162" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "613", "end_pos": "613" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "Q9ET78-1.442.442", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q9ET78-1.470.470", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "Q9ET78-1.479.479", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9ET78-1.470.470", "start_pos": 470, "end_pos": 470, "uniprot_canonical_ac": "Q9ET78-1", "length": 696, "uniprot_id": "JPH2_MOUSE", "protein_name": "Junctophilin-2", "refseq_ac": "NP_001192005", "refseq_name": "junctophilin-2", "gene_name": "Jph2", "gene_names_uniprotkb": "Jph2; Jp2", "gene_names_refseq": "1110002E14Rik; JP-2; Jp2; Jph2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78" }, { "database": "iPTMnet", "id": "Q9ET78", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ET78" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9ET78", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ET78", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "GLGTGLPERPRESPQLHERE", "down_seq": "PQPEGGPPSPAGTPPQPKRP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q9ET78", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ET78" } ], "site_lbl": "Thr470" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "483", "end_pos": "483" }, { "start_pos": "518", "end_pos": "518" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "153", "end_pos": "158" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "488", "end_pos": "492" }, { "start_pos": "563", "end_pos": "568" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "162", "end_pos": "162" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "613", "end_pos": "613" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "Q9ET78-1.462.462", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q9ET78-1.479.479", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q9ET78-1.483.483", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q9ET78-1.488.492", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9ET78-1.479.479", "start_pos": 479, "end_pos": 479, "uniprot_canonical_ac": "Q9ET78-1", "length": 696, "uniprot_id": "JPH2_MOUSE", "protein_name": "Junctophilin-2", "refseq_ac": "NP_001192005", "refseq_name": "junctophilin-2", "gene_name": "Jph2", "gene_names_uniprotkb": "Jph2; Jp2", "gene_names_refseq": "1110002E14Rik; JP-2; Jp2; Jph2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78" }, { "database": "iPTMnet", "id": "Q9ET78", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ET78" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9ET78", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ET78", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PRESPQLHERETPQPEGGPP", "down_seq": "PAGTPPQPKRPRPGASKDGL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q9ET78", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ET78" } ], "site_lbl": "Ser479" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "483", "end_pos": "483" }, { "start_pos": "518", "end_pos": "518" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "153", "end_pos": "158" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "488", "end_pos": "492" }, { "start_pos": "563", "end_pos": "568" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "162", "end_pos": "162" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "613", "end_pos": "613" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "Q9ET78-1.462.462", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "Q9ET78-1.470.470", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q9ET78-1.483.483", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q9ET78-1.488.492", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9ET78-1.527.527", "start_pos": 527, "end_pos": 527, "uniprot_canonical_ac": "Q9ET78-1", "length": 696, "uniprot_id": "JPH2_MOUSE", "protein_name": "Junctophilin-2", "refseq_ac": "NP_001192005", "refseq_name": "junctophilin-2", "gene_name": "Jph2", "gene_names_uniprotkb": "Jph2; Jp2", "gene_names_refseq": "1110002E14Rik; JP-2; Jp2; Jph2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GEPGGEGSRPATPSDGAGRR", "down_seq": "PARPASEHMAIEALQPPPAP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78" } ], "site_lbl": "Ser527" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "483", "end_pos": "483" }, { "start_pos": "518", "end_pos": "518" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "153", "end_pos": "158" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "488", "end_pos": "492" }, { "start_pos": "563", "end_pos": "568" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "162", "end_pos": "162" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "613", "end_pos": "613" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "Q9ET78-1.518.518", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q9ET78-1.533.533", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9ET78-1.533.533", "start_pos": 533, "end_pos": 533, "uniprot_canonical_ac": "Q9ET78-1", "length": 696, "uniprot_id": "JPH2_MOUSE", "protein_name": "Junctophilin-2", "refseq_ac": "NP_001192005", "refseq_name": "junctophilin-2", "gene_name": "Jph2", "gene_names_uniprotkb": "Jph2; Jp2", "gene_names_refseq": "1110002E14Rik; JP-2; Jp2; Jph2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GSRPATPSDGAGRRSPARPA", "down_seq": "EHMAIEALQPPPAPSQEPEV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78" } ], "site_lbl": "Ser533" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "483", "end_pos": "483" }, { "start_pos": "518", "end_pos": "518" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "153", "end_pos": "158" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "488", "end_pos": "492" }, { "start_pos": "563", "end_pos": "568" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "162", "end_pos": "162" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "613", "end_pos": "613" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "Q9ET78-1.518.518", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q9ET78-1.527.527", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9ET78-1.593.593", "start_pos": 593, "end_pos": 593, "uniprot_canonical_ac": "Q9ET78-1", "length": 696, "uniprot_id": "JPH2_MOUSE", "protein_name": "Junctophilin-2", "refseq_ac": "NP_001192005", "refseq_name": "junctophilin-2", "gene_name": "Jph2", "gene_names_uniprotkb": "Jph2; Jp2", "gene_names_refseq": "1110002E14Rik; JP-2; Jp2; Jph2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78" }, { "database": "iPTMnet", "id": "Q9ET78", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ET78" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9ET78", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ET78", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PLEDEQEPEPEPEPEVRRSD", "down_seq": "APPSPVSATVPEEEPPAPRS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q9ET78", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ET78" } ], "site_lbl": "Ser593" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "483", "end_pos": "483" }, { "start_pos": "518", "end_pos": "518" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "153", "end_pos": "158" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "488", "end_pos": "492" }, { "start_pos": "563", "end_pos": "568" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "162", "end_pos": "162" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "613", "end_pos": "613" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "Q9ET78-1.597.597", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "Q9ET78-1.613.613", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9ET78-1.597.597", "start_pos": 597, "end_pos": 597, "uniprot_canonical_ac": "Q9ET78-1", "length": 696, "uniprot_id": "JPH2_MOUSE", "protein_name": "Junctophilin-2", "refseq_ac": "NP_001192005", "refseq_name": "junctophilin-2", "gene_name": "Jph2", "gene_names_uniprotkb": "Jph2; Jp2", "gene_names_refseq": "1110002E14Rik; JP-2; Jp2; Jph2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78" }, { "database": "iPTMnet", "id": "Q9ET78", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ET78" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9ET78", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ET78", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EQEPEPEPEPEVRRSDSAPP", "down_seq": "PVSATVPEEEPPAPRSPVPA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q9ET78", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ET78" } ], "site_lbl": "Ser597" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "483", "end_pos": "483" }, { "start_pos": "518", "end_pos": "518" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "153", "end_pos": "158" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "488", "end_pos": "492" }, { "start_pos": "563", "end_pos": "568" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "162", "end_pos": "162" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "613", "end_pos": "613" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "Q9ET78-1.593.593", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q9ET78-1.613.613", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9ET78-1.613.613", "start_pos": 613, "end_pos": 613, "uniprot_canonical_ac": "Q9ET78-1", "length": 696, "uniprot_id": "JPH2_MOUSE", "protein_name": "Junctophilin-2", "refseq_ac": "NP_001192005", "refseq_name": "junctophilin-2", "gene_name": "Jph2", "gene_names_uniprotkb": "Jph2; Jp2", "gene_names_refseq": "1110002E14Rik; JP-2; Jp2; Jph2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78" }, { "database": "iPTMnet", "id": "Q9ET78", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ET78" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9ET78", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ET78", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SAPPSPVSATVPEEEPPAPR", "down_seq": "PVPAKQATLEPKPIVPKAEP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9ET78", "url": "https://www.uniprot.org/uniprotkb/Q9ET78" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q9ET78", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ET78" } ], "site_lbl": "Ser613" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "483", "end_pos": "483" }, { "start_pos": "518", "end_pos": "518" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "153", "end_pos": "158" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "488", "end_pos": "492" }, { "start_pos": "563", "end_pos": "568" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "162", "end_pos": "162" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "613", "end_pos": "613" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "Q9ET78-1.593.593", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "Q9ET78-1.597.597", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9Z2K1-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "Q9Z2K1-1", "length": 469, "uniprot_id": "K1C16_MOUSE", "protein_name": "Keratin, type I cytoskeletal 16", "refseq_ac": "NP_001300887", "refseq_name": "keratin, type I cytoskeletal 16 isoform 1", "gene_name": "Krt16", "gene_names_uniprotkb": "Krt16; Krt1-16", "gene_names_refseq": "CK-16; K16; Krt1-16; Krt16", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9Z2K1", "url": "https://www.uniprot.org/uniprotkb/Q9Z2K1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Dynamic O-GlcNAcylation governs long-range chromatin interactions in V(D)J recombination during early B-cell development.", "journal": "Cellular & molecular immunology", "date": "2025-01", "authors": "Jeon Bong Chan, Kim Yu-Ji, Park Ae Kyung, Song Mi-Ran, Na Ki Myeong, Lee Juwon, An Dasom, Park Yeseul, Hwang Heeyoun, Kim Tae-Don, Lim Junghyun, Park Sung-Kyun", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9Z2K1", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9Z2K1" } ], "reference": [ { "type": "PubMed", "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609" } ] }, { "title": "Dynamic eIF3a O-GlcNAcylation controls translation reinitiation during nutrient stress.", "journal": "Nature chemical biology", "date": "2022", "authors": "Shu XE, Mao Y, Jia L, Qian SB", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9Z2K1", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9Z2K1" } ], "reference": [ { "type": "PubMed", "id": "34887587", "url": "https://glygen.org/publication/PubMed/34887587" } ] } ], "crossref": [ { "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9Z2K1", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9Z2K1", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "34887587", "url": "https://glygen.org/publication/PubMed/34887587", "database": "PubMed", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "39627609", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39627609" }, { "id": "Q9Z2K1", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9Z2K1" }, { "id": "34887587", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34887587" } ] } ], "all_sites": [], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P16388-1.207.207", "start_pos": 207, "end_pos": 207, "uniprot_canonical_ac": "P16388-1", "length": 495, "uniprot_id": "KCNA1_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily A member 1", "refseq_ac": "NP_034725", "refseq_name": "potassium voltage-gated channel subfamily A member 1", "gene_name": "Kcna1", "gene_names_uniprotkb": "Kcna1", "gene_names_refseq": "Kca1-1; Kcna1; Kv1.1; MBK1; Mk-1; Shak; mceph", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16388", "url": "https://www.uniprot.org/uniprotkb/P16388" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "The brain Kv1.1 potassium channel: in vitro and in vivo studies on subunit assembly and posttranslational processing.", "journal": "The Journal of neuroscience : the official journal of the Society for Neuroscience", "date": "1994", "authors": "Deal KK, Lovinger DM, Tamkun MM", "evidence": [ { "database": "GlyGen", "id": "GLY_000492", "url": "https://data.glygen.org/GLY_000492" } ], "reference": [ { "type": "PubMed", "id": "8126562", "url": "https://glygen.org/publication/PubMed/8126562" } ] } ], "crossref": [ { "id": "P16388", "url": "https://www.uniprot.org/uniprotkb/P16388", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "8126562", "url": "https://glygen.org/publication/PubMed/8126562", "database": "PubMed", "categories": [ "Other" ] }, { "id": "GLY_000492", "url": "https://data.glygen.org/GLY_000492", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "ETLPELKDDKDFTGTIHRID", "down_seq": "TTVIYTSNIFTDPFFIVETL", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true, "automatic_literature_mining": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn207", "evidence": [ { "id": "P16388", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P16388#ptm_processing" }, { "id": "8126562", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/8126562" }, { "id": "GLY_000492", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000492" } ], "mining_tool": "RLIMS-G_1.0;GlycoSiteMiner_1.0", "mining_tool_list": [ { "label": "RLIMS-G_1.0" }, { "label": "GlycoSiteMiner_1.0" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "207", "end_pos": "207" }, { "start_pos": "462", "end_pos": "462" } ] }, { "type": "snv", "site_list": [ { "start_pos": "462", "end_pos": "462" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "437", "end_pos": "437" }, { "start_pos": "439", "end_pos": "439" }, { "start_pos": "446", "end_pos": "446" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl", "mining_tool" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl", "mining_tool" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl", "mining_tool" ] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P16388-1.462.462", "start_pos": 462, "end_pos": 462, "uniprot_canonical_ac": "P16388-1", "length": 495, "uniprot_id": "KCNA1_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily A member 1", "refseq_ac": "NP_034725", "refseq_name": "potassium voltage-gated channel subfamily A member 1", "gene_name": "Kcna1", "gene_names_uniprotkb": "Kcna1", "gene_names_refseq": "Kca1-1; Kcna1; Kv1.1; MBK1; Mk-1; Shak; mceph", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16388", "url": "https://www.uniprot.org/uniprotkb/P16388" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "rs3388859829", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388859829", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "SRRSSSTISKSEYMEIEEDM", "down_seq": "NSIAHYRQANIRTGNCTTAD", "glycosylation": [ { "glytoucan_ac": "G92275SC", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "SEYMEIEEDMNNSIAHYR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn462", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "snv": [ { "evidence": [ { "id": "rs3388859829", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388859829" } ], "glycoeffect": [ "n-glyco-sequon-loss" ], "sequence_org": "N", "sequence_mut": "I", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-loss (NNS->INS).", "chr_id": "6", "chr_pos": "126618934", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "N462", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "207", "end_pos": "207" }, { "start_pos": "462", "end_pos": "462" } ] }, { "type": "snv", "site_list": [ { "start_pos": "462", "end_pos": "462" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "437", "end_pos": "437" }, { "start_pos": "439", "end_pos": "439" }, { "start_pos": "446", "end_pos": "446" } ] } ], "categories": [ "glycosylation_flag", "snv_flag" ], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P16388-1.446.446", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P16388-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "P16388-1", "length": 495, "uniprot_id": "KCNA1_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily A member 1", "refseq_ac": "NP_034725", "refseq_name": "potassium voltage-gated channel subfamily A member 1", "gene_name": "Kcna1", "gene_names_uniprotkb": "Kcna1", "gene_names_refseq": "Kca1-1; Kcna1; Kv1.1; MBK1; Mk-1; Shak; mceph", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16388", "url": "https://www.uniprot.org/uniprotkb/P16388" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "P16388", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P16388" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] } ], "crossref": [ { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P16388", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P16388", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" }, { "id": "P16388", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P16388" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "207", "end_pos": "207" }, { "start_pos": "462", "end_pos": "462" } ] }, { "type": "snv", "site_list": [ { "start_pos": "462", "end_pos": "462" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "437", "end_pos": "437" }, { "start_pos": "439", "end_pos": "439" }, { "start_pos": "446", "end_pos": "446" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P16388-1.23.23", "start_pos": 23, "end_pos": 23, "uniprot_canonical_ac": "P16388-1", "length": 495, "uniprot_id": "KCNA1_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily A member 1", "refseq_ac": "NP_034725", "refseq_name": "potassium voltage-gated channel subfamily A member 1", "gene_name": "Kcna1", "gene_names_uniprotkb": "Kcna1", "gene_names_refseq": "Kca1-1; Kcna1; Kv1.1; MBK1; Mk-1; Shak; mceph", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16388", "url": "https://www.uniprot.org/uniprotkb/P16388" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P16388", "url": "https://www.uniprot.org/uniprotkb/P16388", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VMSGENADEASTAPGHPQDG", "down_seq": "YPRQADHDDHECCERVVINI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P16388", "url": "https://www.uniprot.org/uniprotkb/P16388" } ], "site_lbl": "Ser23" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "207", "end_pos": "207" }, { "start_pos": "462", "end_pos": "462" } ] }, { "type": "snv", "site_list": [ { "start_pos": "462", "end_pos": "462" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "437", "end_pos": "437" }, { "start_pos": "439", "end_pos": "439" }, { "start_pos": "446", "end_pos": "446" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P16388-1.322.322", "start_pos": 322, "end_pos": 322, "uniprot_canonical_ac": "P16388-1", "length": 495, "uniprot_id": "KCNA1_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily A member 1", "refseq_ac": "NP_034725", "refseq_name": "potassium voltage-gated channel subfamily A member 1", "gene_name": "Kcna1", "gene_names_uniprotkb": "Kcna1", "gene_names_refseq": "Kca1-1; Kcna1; Kv1.1; MBK1; Mk-1; Shak; mceph", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16388", "url": "https://www.uniprot.org/uniprotkb/P16388" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P16388", "url": "https://www.uniprot.org/uniprotkb/P16388", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "IFKLSRHSKGLQILGQTLKA", "down_seq": "MRELGLLIFFLFIGVILFSS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by PKA", "evidence": [ { "database": "UniProtKB", "id": "P16388", "url": "https://www.uniprot.org/uniprotkb/P16388" } ], "site_lbl": "Ser322" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "207", "end_pos": "207" }, { "start_pos": "462", "end_pos": "462" } ] }, { "type": "snv", "site_list": [ { "start_pos": "462", "end_pos": "462" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "437", "end_pos": "437" }, { "start_pos": "439", "end_pos": "439" }, { "start_pos": "446", "end_pos": "446" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P16388-1.437.437", "start_pos": 437, "end_pos": 437, "uniprot_canonical_ac": "P16388-1", "length": 495, "uniprot_id": "KCNA1_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily A member 1", "refseq_ac": "NP_034725", "refseq_name": "potassium voltage-gated channel subfamily A member 1", "gene_name": "Kcna1", "gene_names_uniprotkb": "Kcna1", "gene_names_refseq": "Kca1-1; Kcna1; Kv1.1; MBK1; Mk-1; Shak; mceph", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16388", "url": "https://www.uniprot.org/uniprotkb/P16388" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P16388", "url": "https://www.uniprot.org/uniprotkb/P16388", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RETEGEEQAQLLHVSSPNLA", "down_seq": "DSDLSRRSSSTISKSEYMEI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P16388", "url": "https://www.uniprot.org/uniprotkb/P16388" } ], "site_lbl": "Ser437" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "207", "end_pos": "207" }, { "start_pos": "462", "end_pos": "462" } ] }, { "type": "snv", "site_list": [ { "start_pos": "462", "end_pos": "462" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "437", "end_pos": "437" }, { "start_pos": "439", "end_pos": "439" }, { "start_pos": "446", "end_pos": "446" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P16388-1.439.439", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P16388-1.446.446", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P16388-1.439.439", "start_pos": 439, "end_pos": 439, "uniprot_canonical_ac": "P16388-1", "length": 495, "uniprot_id": "KCNA1_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily A member 1", "refseq_ac": "NP_034725", "refseq_name": "potassium voltage-gated channel subfamily A member 1", "gene_name": "Kcna1", "gene_names_uniprotkb": "Kcna1", "gene_names_refseq": "Kca1-1; Kcna1; Kv1.1; MBK1; Mk-1; Shak; mceph", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16388", "url": "https://www.uniprot.org/uniprotkb/P16388" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P16388", "url": "https://www.uniprot.org/uniprotkb/P16388", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TEGEEQAQLLHVSSPNLASD", "down_seq": "DLSRRSSSTISKSEYMEIEE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P16388", "url": "https://www.uniprot.org/uniprotkb/P16388" } ], "site_lbl": "Ser439" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "207", "end_pos": "207" }, { "start_pos": "462", "end_pos": "462" } ] }, { "type": "snv", "site_list": [ { "start_pos": "462", "end_pos": "462" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "437", "end_pos": "437" }, { "start_pos": "439", "end_pos": "439" }, { "start_pos": "446", "end_pos": "446" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P16388-1.437.437", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P16388-1.446.446", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P16388-1.446.446", "start_pos": 446, "end_pos": 446, "uniprot_canonical_ac": "P16388-1", "length": 495, "uniprot_id": "KCNA1_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily A member 1", "refseq_ac": "NP_034725", "refseq_name": "potassium voltage-gated channel subfamily A member 1", "gene_name": "Kcna1", "gene_names_uniprotkb": "Kcna1", "gene_names_refseq": "Kca1-1; Kcna1; Kv1.1; MBK1; Mk-1; Shak; mceph", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16388", "url": "https://www.uniprot.org/uniprotkb/P16388" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P16388", "url": "https://www.uniprot.org/uniprotkb/P16388", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QLLHVSSPNLASDSDLSRRS", "down_seq": "STISKSEYMEIEEDMNNSIA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by PKA", "evidence": [ { "database": "UniProtKB", "id": "P16388", "url": "https://www.uniprot.org/uniprotkb/P16388" } ], "site_lbl": "Ser446" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "207", "end_pos": "207" }, { "start_pos": "462", "end_pos": "462" } ] }, { "type": "snv", "site_list": [ { "start_pos": "462", "end_pos": "462" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "437", "end_pos": "437" }, { "start_pos": "439", "end_pos": "439" }, { "start_pos": "446", "end_pos": "446" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "P16388-1.437.437", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P16388-1.439.439", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P16388-1.462.462", "categories": [ "glycosylation_flag", "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q61923-1.481.481", "start_pos": 481, "end_pos": 481, "uniprot_canonical_ac": "Q61923-1", "length": 529, "uniprot_id": "KCNA6_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily A member 6", "refseq_ac": "NP_038596", "refseq_name": "potassium voltage-gated channel subfamily A member 6", "gene_name": "Kcna6", "gene_names_uniprotkb": "Kcna6", "gene_names_refseq": "Kcna6; Kv1.6; MK1.6", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q61923", "url": "https://www.uniprot.org/uniprotkb/Q61923" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "rs3397260053", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3397260053", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "FNYFYHRETEQEEQGQYTHV", "down_seq": "CGQPTPDLKATDNGLGKPDF", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr481", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "snv": [ { "evidence": [ { "id": "rs3397260053", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3397260053" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "T", "sequence_mut": "I", "comment": "Germline mutation passed 1 filters: o-glyco-site-loss (T->I).", "chr_id": "6", "chr_pos": "126715446", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "T481", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "481", "end_pos": "481" } ] }, { "type": "snv", "site_list": [ { "start_pos": "464", "end_pos": "464" }, { "start_pos": "481", "end_pos": "481" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "3", "end_pos": "3" }, { "start_pos": "511", "end_pos": "511" } ] } ], "categories": [ "glycosylation_flag", "snv_flag" ], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "Q61923-1.464.464", "categories": [ "snv_flag" ] } ], "glycosylation_flag": true, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q61923-1.464.464", "start_pos": 464, "end_pos": 464, "uniprot_canonical_ac": "Q61923-1", "length": 529, "uniprot_id": "KCNA6_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily A member 6", "refseq_ac": "NP_038596", "refseq_name": "potassium voltage-gated channel subfamily A member 6", "gene_name": "Kcna6", "gene_names_uniprotkb": "Kcna6", "gene_names_refseq": "Kcna6; Kv1.6; MK1.6", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q61923", "url": "https://www.uniprot.org/uniprotkb/Q61923" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3544794002", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3544794002", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "F", "start_aa": "F", "up_seq": "IAGVLTIALPVPVIVSNFNY", "down_seq": "YHRETEQEEQGQYTHVTCGQ", "snv": [ { "evidence": [ { "id": "rs3544794002", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3544794002" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "F", "sequence_mut": "C", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (NYF->NYC).", "chr_id": "6", "chr_pos": "126715497", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "F464", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "481", "end_pos": "481" } ] }, { "type": "snv", "site_list": [ { "start_pos": "464", "end_pos": "464" }, { "start_pos": "481", "end_pos": "481" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "3", "end_pos": "3" }, { "start_pos": "511", "end_pos": "511" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "upstream", "id": "Q61923-1.481.481", "categories": [ "glycosylation_flag", "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q61923-1.3.3", "start_pos": 3, "end_pos": 3, "uniprot_canonical_ac": "Q61923-1", "length": 529, "uniprot_id": "KCNA6_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily A member 6", "refseq_ac": "NP_038596", "refseq_name": "potassium voltage-gated channel subfamily A member 6", "gene_name": "Kcna6", "gene_names_uniprotkb": "Kcna6", "gene_names_refseq": "Kcna6; Kv1.6; MK1.6", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q61923", "url": "https://www.uniprot.org/uniprotkb/Q61923" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q61923", "url": "https://www.uniprot.org/uniprotkb/Q61923" }, { "database": "iPTMnet", "id": "Q61923", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q61923" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q61923", "url": "https://www.uniprot.org/uniprotkb/Q61923", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q61923", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q61923", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MR", "down_seq": "EKSLTLAAPGEVRGPEGEQQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q61923", "url": "https://www.uniprot.org/uniprotkb/Q61923" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q61923", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q61923" } ], "site_lbl": "Ser3" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "481", "end_pos": "481" } ] }, { "type": "snv", "site_list": [ { "start_pos": "464", "end_pos": "464" }, { "start_pos": "481", "end_pos": "481" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "3", "end_pos": "3" }, { "start_pos": "511", "end_pos": "511" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q61923-1.511.511", "start_pos": 511, "end_pos": 511, "uniprot_canonical_ac": "Q61923-1", "length": 529, "uniprot_id": "KCNA6_MOUSE", "protein_name": "Potassium voltage-gated channel subfamily A member 6", "refseq_ac": "NP_038596", "refseq_name": "potassium voltage-gated channel subfamily A member 6", "gene_name": "Kcna6", "gene_names_uniprotkb": "Kcna6", "gene_names_refseq": "Kcna6; Kv1.6; MK1.6", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q61923", "url": "https://www.uniprot.org/uniprotkb/Q61923" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q61923", "url": "https://www.uniprot.org/uniprotkb/Q61923", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ATDNGLGKPDFAEASRERRP", "down_seq": "YLPTPHRAYAEKRMLTEV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by PKA", "evidence": [ { "database": "UniProtKB", "id": "Q61923", "url": "https://www.uniprot.org/uniprotkb/Q61923" } ], "site_lbl": "Ser511" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "481", "end_pos": "481" } ] }, { "type": "snv", "site_list": [ { "start_pos": "464", "end_pos": "464" }, { "start_pos": "481", "end_pos": "481" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "3", "end_pos": "3" }, { "start_pos": "511", "end_pos": "511" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9Z0V1-1.153.153", "start_pos": 153, "end_pos": 153, "uniprot_canonical_ac": "Q9Z0V1-1", "length": 655, "uniprot_id": "KCND3_MOUSE", "protein_name": "A-type voltage-gated potassium channel KCND3", "refseq_ac": "NP_001034436", "refseq_name": "A-type voltage-gated potassium channel KCND3 isoform 1", "gene_name": "Kcnd3", "gene_names_uniprotkb": "Kcnd3", "gene_names_refseq": "Kcnd3; Kncd3; Kv4.3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9Z0V1", "url": "https://www.uniprot.org/uniprotkb/Q9Z0V1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9Z0V1", "url": "https://www.uniprot.org/uniprotkb/Q9Z0V1" }, { "database": "iPTMnet", "id": "Q9Z0V1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9Z0V1" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q9Z0V1", "url": "https://www.uniprot.org/uniprotkb/Q9Z0V1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9Z0V1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9Z0V1", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "YEEYKDRKRENAERLMDDND", "down_seq": "ENNQESMPSLSFRQTMWRAF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9Z0V1", "url": "https://www.uniprot.org/uniprotkb/Q9Z0V1" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q9Z0V1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9Z0V1" } ], "site_lbl": "Ser153" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "153", "end_pos": "153" }, { "start_pos": "459", "end_pos": "459" }, { "start_pos": "569", "end_pos": "569" }, { "start_pos": "585", "end_pos": "585" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9Z0V1-1.459.459", "start_pos": 459, "end_pos": 459, "uniprot_canonical_ac": "Q9Z0V1-1", "length": 655, "uniprot_id": "KCND3_MOUSE", "protein_name": "A-type voltage-gated potassium channel KCND3", "refseq_ac": "NP_001034436", "refseq_name": "A-type voltage-gated potassium channel KCND3 isoform 1", "gene_name": "Kcnd3", "gene_names_uniprotkb": "Kcnd3", "gene_names_refseq": "Kcnd3; Kncd3; Kv4.3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9Z0V1", "url": "https://www.uniprot.org/uniprotkb/Q9Z0V1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9Z0V1", "url": "https://www.uniprot.org/uniprotkb/Q9Z0V1" }, { "database": "iPTMnet", "id": "Q9Z0V1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9Z0V1" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q9Z0V1", "url": "https://www.uniprot.org/uniprotkb/Q9Z0V1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9Z0V1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9Z0V1", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "NAYLHSKRNGLLNEALELTG", "down_seq": "PEEEQMGKTTSLIESQHHHL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q9Z0V1", "url": "https://www.uniprot.org/uniprotkb/Q9Z0V1" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q9Z0V1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9Z0V1" } ], "site_lbl": "Thr459" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "153", "end_pos": "153" }, { "start_pos": "459", "end_pos": "459" }, { "start_pos": "569", "end_pos": "569" }, { "start_pos": "585", "end_pos": "585" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9Z0V1-1.569.569", "start_pos": 569, "end_pos": 569, "uniprot_canonical_ac": "Q9Z0V1-1", "length": 655, "uniprot_id": "KCND3_MOUSE", "protein_name": "A-type voltage-gated potassium channel KCND3", "refseq_ac": "NP_001034436", "refseq_name": "A-type voltage-gated potassium channel KCND3 isoform 1", "gene_name": "Kcnd3", "gene_names_uniprotkb": "Kcnd3", "gene_names_refseq": "Kcnd3; Kncd3; Kv4.3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9Z0V1", "url": "https://www.uniprot.org/uniprotkb/Q9Z0V1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9Z0V1", "url": "https://www.uniprot.org/uniprotkb/Q9Z0V1" }, { "database": "iPTMnet", "id": "Q9Z0V1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9Z0V1" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q9Z0V1", "url": "https://www.uniprot.org/uniprotkb/Q9Z0V1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9Z0V1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9Z0V1", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RRSKKTTHLPNSNLPATRLR", "down_seq": "MQELSTLHIQGSEQPSLTTS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9Z0V1", "url": "https://www.uniprot.org/uniprotkb/Q9Z0V1" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q9Z0V1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9Z0V1" } ], "site_lbl": "Ser569" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "153", "end_pos": "153" }, { "start_pos": "459", "end_pos": "459" }, { "start_pos": "569", "end_pos": "569" }, { "start_pos": "585", "end_pos": "585" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "upstream", "id": "Q9Z0V1-1.585.585", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9Z0V1-1.585.585", "start_pos": 585, "end_pos": 585, "uniprot_canonical_ac": "Q9Z0V1-1", "length": 655, "uniprot_id": "KCND3_MOUSE", "protein_name": "A-type voltage-gated potassium channel KCND3", "refseq_ac": "NP_001034436", "refseq_name": "A-type voltage-gated potassium channel KCND3 isoform 1", "gene_name": "Kcnd3", "gene_names_uniprotkb": "Kcnd3", "gene_names_refseq": "Kcnd3; Kncd3; Kv4.3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9Z0V1", "url": "https://www.uniprot.org/uniprotkb/Q9Z0V1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9Z0V1", "url": "https://www.uniprot.org/uniprotkb/Q9Z0V1" }, { "database": "iPTMnet", "id": "Q9Z0V1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9Z0V1" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q9Z0V1", "url": "https://www.uniprot.org/uniprotkb/Q9Z0V1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9Z0V1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9Z0V1", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TRLRSMQELSTLHIQGSEQP", "down_seq": "LTTSRSSLNLKADDGLRPNC", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9Z0V1", "url": "https://www.uniprot.org/uniprotkb/Q9Z0V1" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q9Z0V1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9Z0V1" } ], "site_lbl": "Ser585" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "153", "end_pos": "153" }, { "start_pos": "459", "end_pos": "459" }, { "start_pos": "569", "end_pos": "569" }, { "start_pos": "585", "end_pos": "585" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "Q9Z0V1-1.569.569", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P52480-1.37.37", "start_pos": 37, "end_pos": 37, "uniprot_canonical_ac": "P52480-1", "length": 531, "uniprot_id": "KPYM_MOUSE", "protein_name": "Pyruvate kinase PKM", "refseq_ac": "NP_001240812", "refseq_name": "pyruvate kinase PKM isoform M1", "gene_name": "Pkm", "gene_names_uniprotkb": "Pkm; Pk3; Pkm2; Pykm", "gene_names_refseq": "Pk-2; Pk-3; Pk3; Pkm2; Pkm", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P52480", "url": "https://www.uniprot.org/uniprotkb/P52480" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "P52480", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P52480" }, { "database": "O-GlcNAc Atlas", "id": "P52480", "url": "https://oglcnac.org/atlas/detail/P52480" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Novel Antibodies for the Simple and Efficient Enrichment of Native O-GlcNAc Modified Peptides.", "journal": "Molecular & cellular proteomics : MCP", "date": "2021", "authors": "Burt RA, Dejanovic B, Peckham HJ, Lee KA, Li X, Ounadjela JR, Rao A, Malaker SA, Carr SA, Myers SA", "evidence": [ { "database": "O-GlcNAc Database", "id": "P52480", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P52480" }, { "database": "O-GlcNAc Atlas", "id": "P52480", "url": "https://oglcnac.org/atlas/detail/P52480" } ], "reference": [ { "type": "PubMed", "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516" } ] }, { "title": "Oncogenic TRIB2 interacts with and regulates PKM2 to promote aerobic glycolysis and lung cancer cell procession.", "journal": "Cell death discovery", "date": "2022-07-05", "authors": "Liu Yuan-Rong, Song Dan-Dan, Liang Dong-Min, Li You-Jie, Yan Yun-Fei, Sun Hong-Fang, Zhang Mei-Ling, Hu Jin-Xia, Zhao Yu-Long, Liang Yan, Li Yan-Mei, Yang Zhen, Wang Ran-Ran, Zheng Hou-Feng, Wang Pingyu, Xie Shu-Yang", "evidence": [ { "database": "iPTMnet", "id": "P52480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52480" } ], "reference": [ { "type": "PubMed", "id": "35790734", "url": "https://glygen.org/publication/PubMed/35790734" } ] } ], "crossref": [ { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P52480", "url": "https://oglcnac.org/atlas/detail/P52480", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P52480", "url": "https://www.uniprot.org/uniprotkb/P52480", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P52480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52480", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "35790734", "url": "https://glygen.org/publication/PubMed/35790734", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QLHAAMADTFLEHMCRLDID", "down_seq": "APITARNTGIICTIGPASRS", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser37", "evidence": [ { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "P52480", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P52480" }, { "id": "34678516", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34678516" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P52480", "url": "https://www.uniprot.org/uniprotkb/P52480" }, { "database": "iPTMnet", "id": "P52480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52480" }, { "database": "PubMed", "id": "35790734", "url": "https://glygen.org/publication/PubMed/35790734" } ], "site_lbl": "Ser37" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "37", "end_pos": "37" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "367", "end_pos": "367" }, { "start_pos": "423", "end_pos": "424" }, { "start_pos": "464", "end_pos": "464" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "105", "end_pos": "105" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "175", "end_pos": "175" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "41", "end_pos": "41" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "97", "end_pos": "97" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "P52480-1.41.41", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P52480-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "P52480-1", "length": 531, "uniprot_id": "KPYM_MOUSE", "protein_name": "Pyruvate kinase PKM", "refseq_ac": "NP_001240812", "refseq_name": "pyruvate kinase PKM isoform M1", "gene_name": "Pkm", "gene_names_uniprotkb": "Pkm; Pk3; Pkm2; Pykm", "gene_names_refseq": "Pk-2; Pk-3; Pk3; Pkm2; Pkm", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P52480", "url": "https://www.uniprot.org/uniprotkb/P52480" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Hepatocyte-specific O-GlcNAc transferase downregulation ameliorates nonalcoholic steatohepatitis by improving mitochondrial function.", "journal": "Molecular metabolism", "date": "2023-09", "authors": "Gonzalez-Rellan Maria J, Parracho Tamara, Heras Violeta, Rodriguez Amaia, Fondevila Marcos F, Novoa Eva, Lima Natalia, Varela-Rey Marta, Senra Ana, Chantada-Vazquez Maria D P, Ameneiro Cristina, Bernardo Ganeko, Fernandez-Ramos David, Lopitz-Otsoa Fernando, Bilbao Jon, Guallar Diana, Fidalgo Miguel, Bravo Susana, Dieguez Carlos, Martinez-Chantar Maria L, Millet Oscar, Mato Jose M, Schwaninger Markus, Prevot Vincent, Crespo Javier, Fr\u00fchbeck Gema, Iruzubieta Paula, Nogueiras Ruben", "evidence": [ { "database": "O-GlcNAc Database", "id": "P52480", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P52480" } ], "reference": [ { "type": "PubMed", "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647" } ] }, { "title": "Differential Detection of O-GlcNAcylated proteins in the heart using antibodies.", "journal": "Analytical biochemistry", "date": "2023-10-01", "authors": "Narayanan Bhargavi, Zahra Fiddia, Reeves Russell A, Aggarwal Akanksha, O'Meally Robert N, Henry Roger K, Craven Megan, Jacobson Avital, Cole Robert N, Kohr Mark J, Umapathi Priya, Zachara Natasha E", "evidence": [ { "database": "O-GlcNAc Database", "id": "P52480", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P52480" } ], "reference": [ { "type": "PubMed", "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081" } ] }, { "title": "The New Chemical Reporter 6-Alkynyl-6-deoxy-GlcNAc Reveals O-GlcNAc Modification of the Apoptotic Caspases That Can Block the Cleavage/Activation of Caspase-8.", "journal": "Journal of the American Chemical Society", "date": "2017", "authors": "Chuh KN, Batt AR, Zaro BW, Darabedian N, Marotta NP, Brennan CK, Amirhekmat A, Pratt MR", "evidence": [ { "database": "O-GlcNAc Database", "id": "P52480", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P52480" } ], "reference": [ { "type": "PubMed", "id": "28528544", "url": "https://glygen.org/publication/PubMed/28528544" } ] }, { "title": "First comprehensive identification of cardiac proteins with putative increased O-GlcNAc levels during pressure overload hypertrophy.", "journal": "PloS one", "date": "2022", "authors": "Zhu Wei Zhong, Palazzo Teresa, Zhou Mowei, Ledee Dolena, Olson Heather M, Pa\u0161a-Toli\u0107 Ljiljana, Olson Aaron K", "evidence": [ { "database": "O-GlcNAc Database", "id": "P52480", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P52480" } ], "reference": [ { "type": "PubMed", "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343" } ] }, { "title": "Dynamic eIF3a O-GlcNAcylation controls translation reinitiation during nutrient stress.", "journal": "Nature chemical biology", "date": "2022", "authors": "Shu XE, Mao Y, Jia L, Qian SB", "evidence": [ { "database": "O-GlcNAc Database", "id": "P52480", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P52480" } ], "reference": [ { "type": "PubMed", "id": "34887587", "url": "https://glygen.org/publication/PubMed/34887587" } ] }, { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "P52480", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P52480" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] }, { "title": "A reference dataset of O-GlcNAc proteins in quadriceps skeletal muscle from mice.", "journal": "Glycobiology", "date": "2025-02-10", "authors": "Jaiswal Ruchi, Liu Yimin, Petriello Michael, Zhang Xiangmin, Yi Zhengping, Fehl Charlie", "evidence": [ { "database": "O-GlcNAc Database", "id": "P52480", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P52480" } ], "reference": [ { "type": "PubMed", "id": "39927985", "url": "https://glygen.org/publication/PubMed/39927985" } ] }, { "title": "Enhancing protein O-GlcNAcylation in down syndrome mice mitigates memory dysfunctions through the rescue of mitochondrial bioenergetics, stress responses and pathological markers.", "journal": "Redox biology", "date": "2025-07-16", "authors": "Lanzillotta Chiara, Prestia Francesca, Greco Viviana, Iavarone Federica, Cordella Federica, Sette Chiara, Forte Elena, Tramutola Antonella, Lanzillotta Simona, Cassano Tommaso, Di Angelantonio Silvia, Urbani Andrea, Barone Eugenio, Perluigi Marzia, Di Domenico Fabio", "evidence": [ { "database": "O-GlcNAc Database", "id": "P52480", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P52480" } ], "reference": [ { "type": "PubMed", "id": "40684658", "url": "https://glygen.org/publication/PubMed/40684658" } ] }, { "title": "Dynamic O-GlcNAcylation governs long-range chromatin interactions in V(D)J recombination during early B-cell development.", "journal": "Cellular & molecular immunology", "date": "2025-01", "authors": "Jeon Bong Chan, Kim Yu-Ji, Park Ae Kyung, Song Mi-Ran, Na Ki Myeong, Lee Juwon, An Dasom, Park Yeseul, Hwang Heeyoun, Kim Tae-Don, Lim Junghyun, Park Sung-Kyun", "evidence": [ { "database": "O-GlcNAc Database", "id": "P52480", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P52480" } ], "reference": [ { "type": "PubMed", "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609" } ] }, { "title": "O-GlcNAcylation enhances CPS1 catalytic efficiency for ammonia and promotes ureagenesis.", "journal": "Nature communications", "date": "2022", "authors": "Soria LR, Makris G, D'Alessio AM, De Angelis A, Boffa I, Pravata VM, Rufenacht V, Attanasio S, Nusco E, Arena P, Ferenbach AT, Paris D, Cuomo P, Motta A, Nitzahn M, Lipshutz GS, Martinez-Pizarro A, Richard E, Desviat LR, Haberle J, van Aalten DMF, Brunetti-Pierri N", "evidence": [ { "database": "O-GlcNAc Database", "id": "P52480", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P52480" } ], "reference": [ { "type": "PubMed", "id": "36064721", "url": "https://glygen.org/publication/PubMed/36064721" } ] }, { "title": "Identification of O-GlcNAc modification targets in mouse retinal pericytes: implication of p53 in pathogenesis of diabetic retinopathy.", "journal": "PloS one", "date": "2014", "authors": "Gurel Z, Zaro BW, Pratt MR, Sheibani N", "evidence": [ { "database": "O-GlcNAc Database", "id": "P52480", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P52480" } ], "reference": [ { "type": "PubMed", "id": "24788674", "url": "https://glygen.org/publication/PubMed/24788674" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "P52480", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P52480" }, { "database": "O-GlcNAc Atlas", "id": "P52480", "url": "https://oglcnac.org/atlas/detail/P52480" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Novel Antibodies for the Simple and Efficient Enrichment of Native O-GlcNAc Modified Peptides.", "journal": "Molecular & cellular proteomics : MCP", "date": "2021", "authors": "Burt RA, Dejanovic B, Peckham HJ, Lee KA, Li X, Ounadjela JR, Rao A, Malaker SA, Carr SA, Myers SA", "evidence": [ { "database": "O-GlcNAc Database", "id": "P52480", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P52480" }, { "database": "O-GlcNAc Atlas", "id": "P52480", "url": "https://oglcnac.org/atlas/detail/P52480" } ], "reference": [ { "type": "PubMed", "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516" } ] }, { "title": "Chemical reporters for fluorescent detection and identification of O-GlcNAc-modified proteins reveal glycosylation of the ubiquitin ligase NEDD4-1.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Zaro BW, Yang YY, Hang HC, Pratt MR", "evidence": [ { "database": "O-GlcNAc Database", "id": "P52480", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P52480" } ], "reference": [ { "type": "PubMed", "id": "21540332", "url": "https://glygen.org/publication/PubMed/21540332" } ] } ], "crossref": [ { "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P52480", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P52480", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081", "database": "PubMed", "categories": [ "Other" ] }, { "id": "28528544", "url": "https://glygen.org/publication/PubMed/28528544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343", "database": "PubMed", "categories": [ "Other" ] }, { "id": "34887587", "url": "https://glygen.org/publication/PubMed/34887587", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "39927985", "url": "https://glygen.org/publication/PubMed/39927985", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40684658", "url": "https://glygen.org/publication/PubMed/40684658", "database": "PubMed", "categories": [ "Other" ] }, { "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609", "database": "PubMed", "categories": [ "Other" ] }, { "id": "36064721", "url": "https://glygen.org/publication/PubMed/36064721", "database": "PubMed", "categories": [ "Other" ] }, { "id": "24788674", "url": "https://glygen.org/publication/PubMed/24788674", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21540332", "url": "https://glygen.org/publication/PubMed/21540332", "database": "PubMed", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "37453647", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37453647" }, { "id": "P52480", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P52480" }, { "id": "37507081", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37507081" }, { "id": "28528544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/28528544" }, { "id": "36288343", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36288343" }, { "id": "34887587", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34887587" }, { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" }, { "id": "39927985", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39927985" }, { "id": "40684658", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40684658" }, { "id": "39627609", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39627609" }, { "id": "36064721", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36064721" }, { "id": "24788674", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/24788674" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "34678516", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34678516" }, { "id": "21540332", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/21540332" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "37", "end_pos": "37" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "367", "end_pos": "367" }, { "start_pos": "423", "end_pos": "424" }, { "start_pos": "464", "end_pos": "464" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "105", "end_pos": "105" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "175", "end_pos": "175" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "41", "end_pos": "41" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "97", "end_pos": "97" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 14 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P52480-1.367.367", "start_pos": 367, "end_pos": 367, "uniprot_canonical_ac": "P52480-1", "length": 531, "uniprot_id": "KPYM_MOUSE", "protein_name": "Pyruvate kinase PKM", "refseq_ac": "NP_001240812", "refseq_name": "pyruvate kinase PKM isoform M1", "gene_name": "Pkm", "gene_names_uniprotkb": "Pkm; Pk3; Pkm2; Pykm", "gene_names_refseq": "Pk-2; Pk-3; Pk3; Pkm2; Pkm", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P52480", "url": "https://www.uniprot.org/uniprotkb/P52480" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "The Mammalian Ribo-interactome Reveals Ribosome Functional Diversity and Heterogeneity.", "journal": "Cell", "date": "2017", "authors": "Simsek D, Tiu GC, Flynn RA, Byeon GW, Leppek K, Xu AF, Chang HY, Barna M", "evidence": [ { "database": "UniProtKB", "id": "P52480", "url": "https://www.uniprot.org/uniprotkb/P52480" } ], "reference": [ { "type": "PubMed", "id": "28575669", "url": "https://glygen.org/publication/PubMed/28575669" } ] } ], "crossref": [ { "id": "P52480", "url": "https://www.uniprot.org/uniprotkb/P52480", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "28575669", "url": "https://glygen.org/publication/PubMed/28575669", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "DVANAVLDGADCIMLSGETA", "down_seq": "GDYPLEAVRMQHLIAREAEA", "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "M", "comment": "Abolishes pyruvate kinase activity without affecting interaction with the ribosome.", "evidence": [ { "database": "UniProtKB", "id": "P52480", "url": "https://www.uniprot.org/uniprotkb/P52480" }, { "database": "PubMed", "id": "28575669", "url": "https://glygen.org/publication/PubMed/28575669" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "37", "end_pos": "37" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "367", "end_pos": "367" }, { "start_pos": "423", "end_pos": "424" }, { "start_pos": "464", "end_pos": "464" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "105", "end_pos": "105" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "175", "end_pos": "175" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "41", "end_pos": "41" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "97", "end_pos": "97" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P52480-1.423.424", "start_pos": 423, "end_pos": 424, "uniprot_canonical_ac": "P52480-1", "length": 531, "uniprot_id": "KPYM_MOUSE", "protein_name": "Pyruvate kinase PKM", "refseq_ac": "NP_001240812", "refseq_name": "pyruvate kinase PKM isoform M1", "gene_name": "Pkm", "gene_names_uniprotkb": "Pkm; Pk3; Pkm2; Pykm", "gene_names_refseq": "Pk-2; Pk-3; Pk3; Pkm2; Pkm", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P52480", "url": "https://www.uniprot.org/uniprotkb/P52480" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Metabolic reprogramming by the S-nitroso-CoA reductase system protects against kidney injury.", "journal": "Nature", "date": "2019-01", "authors": "Zhou Hua-Lin, Zhang Rongli, Anand Puneet, Stomberski Colin T, Qian Zhaoxia, Hausladen Alfred, Wang Liwen, Rhee Eugene P, Parikh Samir M, Karumanchi S Ananth, Stamler Jonathan S", "evidence": [ { "database": "UniProtKB", "id": "P52480", "url": "https://www.uniprot.org/uniprotkb/P52480" } ], "reference": [ { "type": "PubMed", "id": "30487609", "url": "https://glygen.org/publication/PubMed/30487609" } ] } ], "crossref": [ { "id": "P52480", "url": "https://www.uniprot.org/uniprotkb/P52480", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "30487609", "url": "https://glygen.org/publication/PubMed/30487609", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "CC", "start_aa": "C", "up_seq": "PITSDPTEAAAVGAVEASFK", "down_seq": "SGAIIVLTKSGRSAHQVARY", "mutagenesis": [ { "sequence_org": "CC", "sequence_mut": "AA", "comment": "In knockin mice; abolished S-nitrosylation, leading to increased pyruvate kinase activity.", "evidence": [ { "database": "UniProtKB", "id": "P52480", "url": "https://www.uniprot.org/uniprotkb/P52480" }, { "database": "PubMed", "id": "30487609", "url": "https://glygen.org/publication/PubMed/30487609" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "37", "end_pos": "37" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "367", "end_pos": "367" }, { "start_pos": "423", "end_pos": "424" }, { "start_pos": "464", "end_pos": "464" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "105", "end_pos": "105" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "175", "end_pos": "175" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "41", "end_pos": "41" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "97", "end_pos": "97" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P52480-1.464.464", "start_pos": 464, "end_pos": 464, "uniprot_canonical_ac": "P52480-1", "length": 531, "uniprot_id": "KPYM_MOUSE", "protein_name": "Pyruvate kinase PKM", "refseq_ac": "NP_001240812", "refseq_name": "pyruvate kinase PKM isoform M1", "gene_name": "Pkm", "gene_names_uniprotkb": "Pkm; Pk3; Pkm2; Pykm", "gene_names_refseq": "Pk-2; Pk-3; Pk3; Pkm2; Pkm", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P52480", "url": "https://www.uniprot.org/uniprotkb/P52480" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "The Mammalian Ribo-interactome Reveals Ribosome Functional Diversity and Heterogeneity.", "journal": "Cell", "date": "2017", "authors": "Simsek D, Tiu GC, Flynn RA, Byeon GW, Leppek K, Xu AF, Chang HY, Barna M", "evidence": [ { "database": "UniProtKB", "id": "P52480", "url": "https://www.uniprot.org/uniprotkb/P52480" } ], "reference": [ { "type": "PubMed", "id": "28575669", "url": "https://glygen.org/publication/PubMed/28575669" } ] } ], "crossref": [ { "id": "P52480", "url": "https://www.uniprot.org/uniprotkb/P52480", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "28575669", "url": "https://glygen.org/publication/PubMed/28575669", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "H", "start_aa": "H", "up_seq": "YRPRAPIIAVTRNPQTARQA", "down_seq": "LYRGIFPVLCKDAVLNAWAE", "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Abolishes amino-acid binding without affecting interaction with the translating ribosome.", "evidence": [ { "database": "UniProtKB", "id": "P52480", "url": "https://www.uniprot.org/uniprotkb/P52480" }, { "database": "PubMed", "id": "28575669", "url": "https://glygen.org/publication/PubMed/28575669" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "37", "end_pos": "37" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "367", "end_pos": "367" }, { "start_pos": "423", "end_pos": "424" }, { "start_pos": "464", "end_pos": "464" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "105", "end_pos": "105" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "175", "end_pos": "175" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "41", "end_pos": "41" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "97", "end_pos": "97" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "P52480-1.454.454", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P52480-1.100.100", "start_pos": 100, "end_pos": 100, "uniprot_canonical_ac": "P52480-1", "length": 531, "uniprot_id": "KPYM_MOUSE", "protein_name": "Pyruvate kinase PKM", "refseq_ac": "NP_001240812", "refseq_name": "pyruvate kinase PKM isoform M1", "gene_name": "Pkm", "gene_names_uniprotkb": "Pkm; Pk3; Pkm2; Pykm", "gene_names_refseq": "Pk-2; Pk-3; Pk3; Pkm2; Pkm", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P52480", "url": "https://www.uniprot.org/uniprotkb/P52480" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P52480", "url": "https://www.uniprot.org/uniprotkb/P52480", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "THEYHAETIKNVREATESFA", "down_seq": "DPILYRPVAVALDTKGPEIR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P52480", "url": "https://www.uniprot.org/uniprotkb/P52480" } ], "site_lbl": "Ser100" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "37", "end_pos": "37" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "367", "end_pos": "367" }, { "start_pos": "423", "end_pos": "424" }, { "start_pos": "464", "end_pos": "464" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "105", "end_pos": "105" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "175", "end_pos": "175" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "41", "end_pos": "41" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "97", "end_pos": "97" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "P52480-1.97.97", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P52480-1.105.105", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P52480-1.105.105", "start_pos": 105, "end_pos": 105, "uniprot_canonical_ac": "P52480-1", "length": 531, "uniprot_id": "KPYM_MOUSE", "protein_name": "Pyruvate kinase PKM", "refseq_ac": "NP_001240812", "refseq_name": "pyruvate kinase PKM isoform M1", "gene_name": "Pkm", "gene_names_uniprotkb": "Pkm; Pk3; Pkm2; Pykm", "gene_names_refseq": "Pk-2; Pk-3; Pk3; Pkm2; Pkm", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P52480", "url": "https://www.uniprot.org/uniprotkb/P52480" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain.", "journal": "Journal of proteome research", "date": "2008", "authors": "Ballif BA, Carey GR, Sunyaev SR, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P52480", "url": "https://www.uniprot.org/uniprotkb/P52480" }, { "database": "iPTMnet", "id": "P52480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52480" } ], "reference": [ { "type": "PubMed", "id": "18034455", "url": "https://glygen.org/publication/PubMed/18034455" } ] }, { "title": "Role of isoenzyme M2 of pyruvate kinase in urothelial tumorigenesis.", "journal": "Oncotarget", "date": "2016", "authors": "Zhou H, Wang X, Mo L, Liu Y, He F, Zhang F, Huang KH, Wu XR", "evidence": [ { "database": "iPTMnet", "id": "P52480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52480" } ], "reference": [ { "type": "PubMed", "id": "26992222", "url": "https://glygen.org/publication/PubMed/26992222" } ] }, { "title": "Prognostic significance and function of the vacuolar H+-ATPase subunit V1E1 in esophageal squamous cell carcinoma.", "journal": "Oncotarget", "date": "2016", "authors": "Son SW, Kim SH, Moon EY, Kim DH, Pyo S, Um SH", "evidence": [ { "database": "iPTMnet", "id": "P52480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52480" } ], "reference": [ { "type": "PubMed", "id": "27384996", "url": "https://glygen.org/publication/PubMed/27384996" } ] }, { "title": "Photoreceptor metabolic reprogramming provides survival advantage in acute stress while causing chronic degeneration.", "journal": "Scientific reports", "date": "2017", "authors": "Wubben TJ, Pawar M, Smith A, Toolan K, Hager H, Besirli CG", "evidence": [ { "database": "iPTMnet", "id": "P52480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52480" } ], "reference": [ { "type": "PubMed", "id": "29259242", "url": "https://glygen.org/publication/PubMed/29259242" } ] }, { "title": "Vacuolar H(+)-ATPase Subunit V0C Regulates Aerobic Glycolysis of Esophageal Cancer Cells via PKM2 Signaling.", "journal": "Cells", "date": "2019", "authors": "Son SW, Chau GC, Kim ST, Um SH", "evidence": [ { "database": "iPTMnet", "id": "P52480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52480" } ], "reference": [ { "type": "PubMed", "id": "31554233", "url": "https://glygen.org/publication/PubMed/31554233" } ] }, { "title": "Annexin A5 regulates hepatic macrophage polarization via directly targeting PKM2 and ameliorates NASH.", "journal": "Redox biology", "date": "2020", "authors": "Xu F, Guo M, Huang W, Feng L, Zhu J, Luo K, Gao J, Zheng B, Kong LD, Pang T, Wu X, Xu Q", "evidence": [ { "database": "iPTMnet", "id": "P52480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52480" } ], "reference": [ { "type": "PubMed", "id": "32863213", "url": "https://glygen.org/publication/PubMed/32863213" } ] }, { "title": "Increased SUMO-activating enzyme SAE1/UBA2 promotes glycolysis and pathogenic behavior of rheumatoid fibroblast-like synoviocytes.", "journal": "JCI insight", "date": "2020", "authors": "Wang C, Xiao Y, Lao M, Wang J, Xu S, Li R, Xu X, Kuang Y, Shi M, Zou Y, Wang Q, Liang L, Zheng SG, Xu H", "evidence": [ { "database": "iPTMnet", "id": "P52480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52480" } ], "reference": [ { "type": "PubMed", "id": "32938830", "url": "https://glygen.org/publication/PubMed/32938830" } ] }, { "title": "Cynaroside prevents macrophage polarization into pro-inflammatory phenotype and alleviates cecal ligation and puncture-induced liver injury by targeting PKM2/HIF-1\u03b1 axis.", "journal": "Fitoterapia", "date": "2021-07", "authors": "Pei Liuhua, Le Yifei, Chen Hang, Feng Jiafan, Liu Zhijun, Zhu Ji, Wang Cui, Chen Lin, Dou Xiaobing, Lu Dezhao", "evidence": [ { "database": "iPTMnet", "id": "P52480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52480" } ], "reference": [ { "type": "PubMed", "id": "33984439", "url": "https://glygen.org/publication/PubMed/33984439" } ] } ], "crossref": [ { "id": "P52480", "url": "https://www.uniprot.org/uniprotkb/P52480", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18034455", "url": "https://glygen.org/publication/PubMed/18034455", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P52480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52480", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "26992222", "url": "https://glygen.org/publication/PubMed/26992222", "database": "PubMed", "categories": [ "Other" ] }, { "id": "27384996", "url": "https://glygen.org/publication/PubMed/27384996", "database": "PubMed", "categories": [ "Other" ] }, { "id": "29259242", "url": "https://glygen.org/publication/PubMed/29259242", "database": "PubMed", "categories": [ "Other" ] }, { "id": "31554233", "url": "https://glygen.org/publication/PubMed/31554233", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32863213", "url": "https://glygen.org/publication/PubMed/32863213", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32938830", "url": "https://glygen.org/publication/PubMed/32938830", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33984439", "url": "https://glygen.org/publication/PubMed/33984439", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "AETIKNVREATESFASDPIL", "down_seq": "RPVAVALDTKGPEIRTGLIK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "P52480", "url": "https://www.uniprot.org/uniprotkb/P52480" }, { "database": "PubMed", "id": "18034455", "url": "https://glygen.org/publication/PubMed/18034455" }, { "database": "iPTMnet", "id": "P52480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52480" }, { "database": "PubMed", "id": "26992222", "url": "https://glygen.org/publication/PubMed/26992222" }, { "database": "PubMed", "id": "27384996", "url": "https://glygen.org/publication/PubMed/27384996" }, { "database": "PubMed", "id": "29259242", "url": "https://glygen.org/publication/PubMed/29259242" }, { "database": "PubMed", "id": "31554233", "url": "https://glygen.org/publication/PubMed/31554233" }, { "database": "PubMed", "id": "32863213", "url": "https://glygen.org/publication/PubMed/32863213" }, { "database": "PubMed", "id": "32938830", "url": "https://glygen.org/publication/PubMed/32938830" }, { "database": "PubMed", "id": "33984439", "url": "https://glygen.org/publication/PubMed/33984439" } ], "site_lbl": "Tyr105" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "37", "end_pos": "37" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "367", "end_pos": "367" }, { "start_pos": "423", "end_pos": "424" }, { "start_pos": "464", "end_pos": "464" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "105", "end_pos": "105" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "175", "end_pos": "175" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "41", "end_pos": "41" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "97", "end_pos": "97" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "P52480-1.97.97", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P52480-1.100.100", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P52480-1.127.127", "start_pos": 127, "end_pos": 127, "uniprot_canonical_ac": "P52480-1", "length": 531, "uniprot_id": "KPYM_MOUSE", "protein_name": "Pyruvate kinase PKM", "refseq_ac": "NP_001240812", "refseq_name": "pyruvate kinase PKM isoform M1", "gene_name": "Pkm", "gene_names_uniprotkb": "Pkm; Pk3; Pkm2; Pykm", "gene_names_refseq": "Pk-2; Pk-3; Pk3; Pkm2; Pkm", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P52480", "url": "https://www.uniprot.org/uniprotkb/P52480" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P52480", "url": "https://www.uniprot.org/uniprotkb/P52480", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PVAVALDTKGPEIRTGLIKG", "down_seq": "GTAEVELKKGATLKITLDNA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P52480", "url": "https://www.uniprot.org/uniprotkb/P52480" } ], "site_lbl": "Ser127" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "37", "end_pos": "37" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "367", "end_pos": "367" }, { "start_pos": "423", "end_pos": "424" }, { "start_pos": "464", "end_pos": "464" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "105", "end_pos": "105" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "175", "end_pos": "175" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "41", "end_pos": "41" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "97", "end_pos": "97" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P52480-1.148.148", "start_pos": 148, "end_pos": 148, "uniprot_canonical_ac": "P52480-1", "length": 531, "uniprot_id": "KPYM_MOUSE", "protein_name": "Pyruvate kinase PKM", "refseq_ac": "NP_001240812", "refseq_name": "pyruvate kinase PKM isoform M1", "gene_name": "Pkm", "gene_names_uniprotkb": "Pkm; Pk3; Pkm2; Pykm", "gene_names_refseq": "Pk-2; Pk-3; Pk3; Pkm2; Pkm", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P52480", "url": "https://www.uniprot.org/uniprotkb/P52480" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain.", "journal": "Journal of proteome research", "date": "2008", "authors": "Ballif BA, Carey GR, Sunyaev SR, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P52480", "url": "https://www.uniprot.org/uniprotkb/P52480" }, { "database": "iPTMnet", "id": "P52480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52480" } ], "reference": [ { "type": "PubMed", "id": "18034455", "url": "https://glygen.org/publication/PubMed/18034455" } ] } ], "crossref": [ { "id": "P52480", "url": "https://www.uniprot.org/uniprotkb/P52480", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18034455", "url": "https://glygen.org/publication/PubMed/18034455", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P52480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52480", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "GTAEVELKKGATLKITLDNA", "down_seq": "MEKCDENILWLDYKNICKVV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "P52480", "url": "https://www.uniprot.org/uniprotkb/P52480" }, { "database": "PubMed", "id": "18034455", "url": "https://glygen.org/publication/PubMed/18034455" }, { "database": "iPTMnet", "id": "P52480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52480" } ], "site_lbl": "Tyr148" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "37", "end_pos": "37" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "367", "end_pos": "367" }, { "start_pos": "423", "end_pos": "424" }, { "start_pos": "464", "end_pos": "464" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "105", "end_pos": "105" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "175", "end_pos": "175" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "41", "end_pos": "41" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "97", "end_pos": "97" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P52480-1.175.175", "start_pos": 175, "end_pos": 175, "uniprot_canonical_ac": "P52480-1", "length": 531, "uniprot_id": "KPYM_MOUSE", "protein_name": "Pyruvate kinase PKM", "refseq_ac": "NP_001240812", "refseq_name": "pyruvate kinase PKM isoform M1", "gene_name": "Pkm", "gene_names_uniprotkb": "Pkm; Pk3; Pkm2; Pykm", "gene_names_refseq": "Pk-2; Pk-3; Pk3; Pkm2; Pkm", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P52480", "url": "https://www.uniprot.org/uniprotkb/P52480" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P52480", "url": "https://www.uniprot.org/uniprotkb/P52480", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "NILWLDYKNICKVVEVGSKI", "down_seq": "VDDGLISLQVKEKGADFLVT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "P52480", "url": "https://www.uniprot.org/uniprotkb/P52480" } ], "site_lbl": "Tyr175" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "37", "end_pos": "37" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "367", "end_pos": "367" }, { "start_pos": "423", "end_pos": "424" }, { "start_pos": "464", "end_pos": "464" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "105", "end_pos": "105" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "175", "end_pos": "175" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "41", "end_pos": "41" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "97", "end_pos": "97" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "upstream", "id": "P52480-1.195.195", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P52480-1.195.195", "start_pos": 195, "end_pos": 195, "uniprot_canonical_ac": "P52480-1", "length": 531, "uniprot_id": "KPYM_MOUSE", "protein_name": "Pyruvate kinase PKM", "refseq_ac": "NP_001240812", "refseq_name": "pyruvate kinase PKM isoform M1", "gene_name": "Pkm", "gene_names_uniprotkb": "Pkm; Pk3; Pkm2; Pykm", "gene_names_refseq": "Pk-2; Pk-3; Pk3; Pkm2; Pkm", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P52480", "url": "https://www.uniprot.org/uniprotkb/P52480" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P52480", "url": "https://www.uniprot.org/uniprotkb/P52480", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "YVDDGLISLQVKEKGADFLV", "down_seq": "EVENGGSLGSKKGVNLPGAA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P52480", "url": "https://www.uniprot.org/uniprotkb/P52480" } ], "site_lbl": "Thr195" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "37", "end_pos": "37" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "367", "end_pos": "367" }, { "start_pos": "423", "end_pos": "424" }, { "start_pos": "464", "end_pos": "464" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "105", "end_pos": "105" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "175", "end_pos": "175" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "41", "end_pos": "41" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "97", "end_pos": "97" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P52480-1.175.175", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P52480-1.41.41", "start_pos": 41, "end_pos": 41, "uniprot_canonical_ac": "P52480-1", "length": 531, "uniprot_id": "KPYM_MOUSE", "protein_name": "Pyruvate kinase PKM", "refseq_ac": "NP_001240812", "refseq_name": "pyruvate kinase PKM isoform M1", "gene_name": "Pkm", "gene_names_uniprotkb": "Pkm; Pk3; Pkm2; Pykm", "gene_names_refseq": "Pk-2; Pk-3; Pk3; Pkm2; Pkm", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P52480", "url": "https://www.uniprot.org/uniprotkb/P52480" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P52480", "url": "https://www.uniprot.org/uniprotkb/P52480", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "AMADTFLEHMCRLDIDSAPI", "down_seq": "ARNTGIICTIGPASRSVEML", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P52480", "url": "https://www.uniprot.org/uniprotkb/P52480" } ], "site_lbl": "Thr41" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "37", "end_pos": "37" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "367", "end_pos": "367" }, { "start_pos": "423", "end_pos": "424" }, { "start_pos": "464", "end_pos": "464" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "105", "end_pos": "105" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "175", "end_pos": "175" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "41", "end_pos": "41" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "97", "end_pos": "97" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "P52480-1.37.37", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P52480-1.454.454", "start_pos": 454, "end_pos": 454, "uniprot_canonical_ac": "P52480-1", "length": 531, "uniprot_id": "KPYM_MOUSE", "protein_name": "Pyruvate kinase PKM", "refseq_ac": "NP_001240812", "refseq_name": "pyruvate kinase PKM isoform M1", "gene_name": "Pkm", "gene_names_uniprotkb": "Pkm; Pk3; Pkm2; Pykm", "gene_names_refseq": "Pk-2; Pk-3; Pk3; Pkm2; Pkm", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P52480", "url": "https://www.uniprot.org/uniprotkb/P52480" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Proviral insertion in murine lymphomas 2 (PIM2) oncogene phosphorylates pyruvate kinase M2 (PKM2) and promotes glycolysis in cancer cells.", "journal": "The Journal of biological chemistry", "date": "2013", "authors": "Yu Z, Zhao X, Huang L, Zhang T, Yang F, Xie L, Song S, Miao P, Zhao L, Sun X, Liu J, Huang G", "evidence": [ { "database": "iPTMnet", "id": "P52480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52480" } ], "reference": [ { "type": "PubMed", "id": "24142698", "url": "https://glygen.org/publication/PubMed/24142698" } ] } ], "crossref": [ { "id": "P52480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52480", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "24142698", "url": "https://glygen.org/publication/PubMed/24142698", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "SGRSAHQVARYRPRAPIIAV", "down_seq": "RNPQTARQAHLYRGIFPVLC", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "Q62070-1", "kinase_gene_name": "Pim2", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P52480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52480" }, { "database": "PubMed", "id": "24142698", "url": "https://glygen.org/publication/PubMed/24142698" } ], "site_lbl": "Thr454" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "37", "end_pos": "37" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "367", "end_pos": "367" }, { "start_pos": "423", "end_pos": "424" }, { "start_pos": "464", "end_pos": "464" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "105", "end_pos": "105" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "175", "end_pos": "175" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "41", "end_pos": "41" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "97", "end_pos": "97" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "upstream", "id": "P52480-1.464.464", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P52480-1.97.97", "start_pos": 97, "end_pos": 97, "uniprot_canonical_ac": "P52480-1", "length": 531, "uniprot_id": "KPYM_MOUSE", "protein_name": "Pyruvate kinase PKM", "refseq_ac": "NP_001240812", "refseq_name": "pyruvate kinase PKM isoform M1", "gene_name": "Pkm", "gene_names_uniprotkb": "Pkm; Pk3; Pkm2; Pykm", "gene_names_refseq": "Pk-2; Pk-3; Pk3; Pkm2; Pkm", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P52480", "url": "https://www.uniprot.org/uniprotkb/P52480" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P52480", "url": "https://www.uniprot.org/uniprotkb/P52480", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SHGTHEYHAETIKNVREATE", "down_seq": "FASDPILYRPVAVALDTKGP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P52480", "url": "https://www.uniprot.org/uniprotkb/P52480" } ], "site_lbl": "Ser97" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "37", "end_pos": "37" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "367", "end_pos": "367" }, { "start_pos": "423", "end_pos": "424" }, { "start_pos": "464", "end_pos": "464" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "105", "end_pos": "105" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "175", "end_pos": "175" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "41", "end_pos": "41" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "97", "end_pos": "97" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "P52480-1.100.100", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P52480-1.105.105", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q6ZQ88-1.782.782", "start_pos": 782, "end_pos": 782, "uniprot_canonical_ac": "Q6ZQ88-1", "length": 853, "uniprot_id": "KDM1A_MOUSE", "protein_name": "Lysine-specific histone demethylase 1A", "refseq_ac": "NP_001334150", "refseq_name": "lysine-specific histone demethylase 1A isoform 1", "gene_name": "Kdm1a", "gene_names_uniprotkb": "Kdm1a; Aof2; Kiaa0601; Lsd1", "gene_names_refseq": "1810043O07Rik; Aof2; D4Ertd478e; Kdm1a; Kdm1; Lsd1; mKIAA0601", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6ZQ88", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ88" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "YSYVAAGSSGNDYDLMAQPI", "down_seq": "PGPSIPGAPQPIPRLFFAGE", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr782", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "782", "end_pos": "782" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "89", "end_pos": "89" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "850", "end_pos": "850" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q6ZQ88-1.842.842", "start_pos": 842, "end_pos": 842, "uniprot_canonical_ac": "Q6ZQ88-1", "length": 853, "uniprot_id": "KDM1A_MOUSE", "protein_name": "Lysine-specific histone demethylase 1A", "refseq_ac": "NP_001334150", "refseq_name": "lysine-specific histone demethylase 1A isoform 1", "gene_name": "Kdm1a", "gene_names_uniprotkb": "Kdm1a; Aof2; Kiaa0601; Lsd1", "gene_names_refseq": "1810043O07Rik; Aof2; D4Ertd478e; Kdm1a; Kdm1; Lsd1; mKIAA0601", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6ZQ88", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ88" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "EAGRIADQFLGAMYTLPRQA", "down_seq": "PGVPAQQSPSM", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr842", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "782", "end_pos": "782" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "89", "end_pos": "89" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "850", "end_pos": "850" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "upstream", "id": "Q6ZQ88-1.850.850", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q6ZQ88-1.89.89", "start_pos": 89, "end_pos": 89, "uniprot_canonical_ac": "Q6ZQ88-1", "length": 853, "uniprot_id": "KDM1A_MOUSE", "protein_name": "Lysine-specific histone demethylase 1A", "refseq_ac": "NP_001334150", "refseq_name": "lysine-specific histone demethylase 1A isoform 1", "gene_name": "Kdm1a", "gene_names_uniprotkb": "Kdm1a; Aof2; Kiaa0601; Lsd1", "gene_names_refseq": "1810043O07Rik; Aof2; D4Ertd478e; Kdm1a; Kdm1; Lsd1; mKIAA0601", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6ZQ88", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ88" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "ASPPGGLAEPPGSAGPQAGP", "down_seq": "AGPGSATPMETGIAETPEGR", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr89", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "782", "end_pos": "782" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "89", "end_pos": "89" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "850", "end_pos": "850" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "upstream", "id": "Q6ZQ88-1.105.105", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q6ZQ88-1.105.105", "start_pos": 105, "end_pos": 105, "uniprot_canonical_ac": "Q6ZQ88-1", "length": 853, "uniprot_id": "KDM1A_MOUSE", "protein_name": "Lysine-specific histone demethylase 1A", "refseq_ac": "NP_001334150", "refseq_name": "lysine-specific histone demethylase 1A isoform 1", "gene_name": "Kdm1a", "gene_names_uniprotkb": "Kdm1a; Aof2; Kiaa0601; Lsd1", "gene_names_refseq": "1810043O07Rik; Aof2; D4Ertd478e; Kdm1a; Kdm1; Lsd1; mKIAA0601", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6ZQ88", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ88" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q6ZQ88", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ88", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "QAGPTAGPGSATPMETGIAE", "down_seq": "PEGRRTSRRKRAKVEYREMD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q6ZQ88", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ88" } ], "site_lbl": "Thr105" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "782", "end_pos": "782" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "89", "end_pos": "89" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "850", "end_pos": "850" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "Q6ZQ88-1.89.89", "categories": [ "glycosylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q6ZQ88-1.112.112", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q6ZQ88-1.112.112", "start_pos": 112, "end_pos": 112, "uniprot_canonical_ac": "Q6ZQ88-1", "length": 853, "uniprot_id": "KDM1A_MOUSE", "protein_name": "Lysine-specific histone demethylase 1A", "refseq_ac": "NP_001334150", "refseq_name": "lysine-specific histone demethylase 1A isoform 1", "gene_name": "Kdm1a", "gene_names_uniprotkb": "Kdm1a; Aof2; Kiaa0601; Lsd1", "gene_names_refseq": "1810043O07Rik; Aof2; D4Ertd478e; Kdm1a; Kdm1; Lsd1; mKIAA0601", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6ZQ88", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ88" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Phosphorylation of LSD1 at Ser112 is crucial for its function in induction of EMT and metastasis in breast cancer.", "journal": "Breast cancer research and treatment", "date": "2016", "authors": "Feng J, Xu G, Liu J, Zhang N, Li L, Ji J, Zhang J, Zhang L, Wang G, Wang X, Tan J, Huang B, Lu J, Zhang Y", "evidence": [ { "database": "iPTMnet", "id": "Q6ZQ88", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6ZQ88" } ], "reference": [ { "type": "PubMed", "id": "27572339", "url": "https://glygen.org/publication/PubMed/27572339" } ] }, { "title": "PKCalpha-mediated phosphorylation of LSD1 is required for presynaptic plasticity and hippocampal learning and memory.", "journal": "Scientific reports", "date": "2017", "authors": "Lim CS, Nam HJ, Lee J, Kim D, Choi JE, Kang SJ, Kim S, Kim H, Kwak C, Shim KW, Kim S, Ko HG, Lee RU, Jang EH, Yoo J, Shim J, Islam MA, Lee YS, Lee JH, Baek SH, Kaang BK", "evidence": [ { "database": "iPTMnet", "id": "Q6ZQ88", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6ZQ88" } ], "reference": [ { "type": "PubMed", "id": "28687800", "url": "https://glygen.org/publication/PubMed/28687800" } ] } ], "crossref": [ { "id": "Q6ZQ88", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6ZQ88", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "27572339", "url": "https://glygen.org/publication/PubMed/27572339", "database": "PubMed", "categories": [ "Other" ] }, { "id": "28687800", "url": "https://glygen.org/publication/PubMed/28687800", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PGSATPMETGIAETPEGRRT", "down_seq": "RRKRAKVEYREMDESLANLS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q6ZQ88", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6ZQ88" }, { "database": "PubMed", "id": "27572339", "url": "https://glygen.org/publication/PubMed/27572339" }, { "database": "PubMed", "id": "28687800", "url": "https://glygen.org/publication/PubMed/28687800" } ], "site_lbl": "Ser112" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "782", "end_pos": "782" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "89", "end_pos": "89" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "850", "end_pos": "850" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "Q6ZQ88-1.105.105", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q6ZQ88-1.127.127", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "Q6ZQ88-1.132.132", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6ZQ88-1.127.127", "start_pos": 127, "end_pos": 127, "uniprot_canonical_ac": "Q6ZQ88-1", "length": 853, "uniprot_id": "KDM1A_MOUSE", "protein_name": "Lysine-specific histone demethylase 1A", "refseq_ac": "NP_001334150", "refseq_name": "lysine-specific histone demethylase 1A isoform 1", "gene_name": "Kdm1a", "gene_names_uniprotkb": "Kdm1a; Aof2; Kiaa0601; Lsd1", "gene_names_refseq": "1810043O07Rik; Aof2; D4Ertd478e; Kdm1a; Kdm1; Lsd1; mKIAA0601", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6ZQ88", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ88" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q6ZQ88", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ88", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EGRRTSRRKRAKVEYREMDE", "down_seq": "LANLSEDEYYSEEERNAKAE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q6ZQ88", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ88" } ], "site_lbl": "Ser127" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "782", "end_pos": "782" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "89", "end_pos": "89" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "850", "end_pos": "850" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "Q6ZQ88-1.112.112", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q6ZQ88-1.132.132", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q6ZQ88-1.136.136", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q6ZQ88-1.138.138", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q6ZQ88-1.132.132", "start_pos": 132, "end_pos": 132, "uniprot_canonical_ac": "Q6ZQ88-1", "length": 853, "uniprot_id": "KDM1A_MOUSE", "protein_name": "Lysine-specific histone demethylase 1A", "refseq_ac": "NP_001334150", "refseq_name": "lysine-specific histone demethylase 1A isoform 1", "gene_name": "Kdm1a", "gene_names_uniprotkb": "Kdm1a; Aof2; Kiaa0601; Lsd1", "gene_names_refseq": "1810043O07Rik; Aof2; D4Ertd478e; Kdm1a; Kdm1; Lsd1; mKIAA0601", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6ZQ88", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ88" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q6ZQ88", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ88" }, { "database": "iPTMnet", "id": "Q6ZQ88", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6ZQ88" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q6ZQ88", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ88", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q6ZQ88", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6ZQ88", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SRRKRAKVEYREMDESLANL", "down_seq": "EDEYYSEEERNAKAEKEKKL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q6ZQ88", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ88" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q6ZQ88", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6ZQ88" } ], "site_lbl": "Ser132" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "782", "end_pos": "782" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "89", "end_pos": "89" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "850", "end_pos": "850" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "Q6ZQ88-1.112.112", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q6ZQ88-1.127.127", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q6ZQ88-1.136.136", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q6ZQ88-1.138.138", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6ZQ88-1.136.136", "start_pos": 136, "end_pos": 136, "uniprot_canonical_ac": "Q6ZQ88-1", "length": 853, "uniprot_id": "KDM1A_MOUSE", "protein_name": "Lysine-specific histone demethylase 1A", "refseq_ac": "NP_001334150", "refseq_name": "lysine-specific histone demethylase 1A isoform 1", "gene_name": "Kdm1a", "gene_names_uniprotkb": "Kdm1a; Aof2; Kiaa0601; Lsd1", "gene_names_refseq": "1810043O07Rik; Aof2; D4Ertd478e; Kdm1a; Kdm1; Lsd1; mKIAA0601", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6ZQ88", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ88" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q6ZQ88", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ88", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "RAKVEYREMDESLANLSEDE", "down_seq": "YSEEERNAKAEKEKKLPPPP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "Q6ZQ88", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ88" } ], "site_lbl": "Tyr136" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "782", "end_pos": "782" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "89", "end_pos": "89" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "850", "end_pos": "850" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "Q6ZQ88-1.127.127", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q6ZQ88-1.132.132", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q6ZQ88-1.138.138", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q6ZQ88-1.138.138", "start_pos": 138, "end_pos": 138, "uniprot_canonical_ac": "Q6ZQ88-1", "length": 853, "uniprot_id": "KDM1A_MOUSE", "protein_name": "Lysine-specific histone demethylase 1A", "refseq_ac": "NP_001334150", "refseq_name": "lysine-specific histone demethylase 1A isoform 1", "gene_name": "Kdm1a", "gene_names_uniprotkb": "Kdm1a; Aof2; Kiaa0601; Lsd1", "gene_names_refseq": "1810043O07Rik; Aof2; D4Ertd478e; Kdm1a; Kdm1; Lsd1; mKIAA0601", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6ZQ88", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ88" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q6ZQ88", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ88" }, { "database": "iPTMnet", "id": "Q6ZQ88", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6ZQ88" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q6ZQ88", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ88", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q6ZQ88", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6ZQ88", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KVEYREMDESLANLSEDEYY", "down_seq": "EEERNAKAEKEKKLPPPPPQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q6ZQ88", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ88" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q6ZQ88", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6ZQ88" } ], "site_lbl": "Ser138" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "782", "end_pos": "782" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "89", "end_pos": "89" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "850", "end_pos": "850" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "Q6ZQ88-1.127.127", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q6ZQ88-1.132.132", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q6ZQ88-1.136.136", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6ZQ88-1.167.167", "start_pos": 167, "end_pos": 167, "uniprot_canonical_ac": "Q6ZQ88-1", "length": 853, "uniprot_id": "KDM1A_MOUSE", "protein_name": "Lysine-specific histone demethylase 1A", "refseq_ac": "NP_001334150", "refseq_name": "lysine-specific histone demethylase 1A isoform 1", "gene_name": "Kdm1a", "gene_names_uniprotkb": "Kdm1a; Aof2; Kiaa0601; Lsd1", "gene_names_refseq": "1810043O07Rik; Aof2; D4Ertd478e; Kdm1a; Kdm1; Lsd1; mKIAA0601", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6ZQ88", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ88" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "The phagosomal proteome in interferon-gamma-activated macrophages.", "journal": "Immunity", "date": "2009", "authors": "Trost M, English L, Lemieux S, Courcelles M, Desjardins M, Thibault P", "evidence": [ { "database": "UniProtKB", "id": "Q6ZQ88", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ88" }, { "database": "iPTMnet", "id": "Q6ZQ88", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6ZQ88" } ], "reference": [ { "type": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" } ] } ], "crossref": [ { "id": "Q6ZQ88", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ88", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q6ZQ88", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6ZQ88", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EKEKKLPPPPPQAPPEEENE", "down_seq": "EPEEPSGVEGAAFQSRLPHD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q6ZQ88", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ88" }, { "database": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" }, { "database": "iPTMnet", "id": "Q6ZQ88", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6ZQ88" } ], "site_lbl": "Ser167" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "782", "end_pos": "782" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "89", "end_pos": "89" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "850", "end_pos": "850" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6ZQ88-1.60.60", "start_pos": 60, "end_pos": 60, "uniprot_canonical_ac": "Q6ZQ88-1", "length": 853, "uniprot_id": "KDM1A_MOUSE", "protein_name": "Lysine-specific histone demethylase 1A", "refseq_ac": "NP_001334150", "refseq_name": "lysine-specific histone demethylase 1A isoform 1", "gene_name": "Kdm1a", "gene_names_uniprotkb": "Kdm1a; Aof2; Kiaa0601; Lsd1", "gene_names_refseq": "1810043O07Rik; Aof2; D4Ertd478e; Kdm1a; Kdm1; Lsd1; mKIAA0601", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6ZQ88", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ88" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q6ZQ88", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ88", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "APPAGLTGPTDMATGAAGER", "down_seq": "PRKKEPPRASPPGGLAEPPG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q6ZQ88", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ88" } ], "site_lbl": "Thr60" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "782", "end_pos": "782" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "89", "end_pos": "89" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "850", "end_pos": "850" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q6ZQ88-1.612.612", "start_pos": 612, "end_pos": 612, "uniprot_canonical_ac": "Q6ZQ88-1", "length": 853, "uniprot_id": "KDM1A_MOUSE", "protein_name": "Lysine-specific histone demethylase 1A", "refseq_ac": "NP_001334150", "refseq_name": "lysine-specific histone demethylase 1A isoform 1", "gene_name": "Kdm1a", "gene_names_uniprotkb": "Kdm1a; Aof2; Kiaa0601; Lsd1", "gene_names_refseq": "1810043O07Rik; Aof2; D4Ertd478e; Kdm1a; Kdm1; Lsd1; mKIAA0601", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6ZQ88", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ88" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q6ZQ88", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ88", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RQVRYTASGCEVIAVNTRST", "down_seq": "QTFIYKCDAVLCTLPLGVLK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q6ZQ88", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ88" } ], "site_lbl": "Ser612" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "782", "end_pos": "782" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "89", "end_pos": "89" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "850", "end_pos": "850" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q6ZQ88-1.850.850", "start_pos": 850, "end_pos": 850, "uniprot_canonical_ac": "Q6ZQ88-1", "length": 853, "uniprot_id": "KDM1A_MOUSE", "protein_name": "Lysine-specific histone demethylase 1A", "refseq_ac": "NP_001334150", "refseq_name": "lysine-specific histone demethylase 1A isoform 1", "gene_name": "Kdm1a", "gene_names_uniprotkb": "Kdm1a; Aof2; Kiaa0601; Lsd1", "gene_names_refseq": "1810043O07Rik; Aof2; D4Ertd478e; Kdm1a; Kdm1; Lsd1; mKIAA0601", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6ZQ88", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ88" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q6ZQ88", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ88", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "FLGAMYTLPRQATPGVPAQQ", "down_seq": "PSM", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q6ZQ88", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ88" } ], "site_lbl": "Ser850" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "782", "end_pos": "782" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "89", "end_pos": "89" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "850", "end_pos": "850" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "Q6ZQ88-1.842.842", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8K1Y2-1.203.203", "start_pos": 203, "end_pos": 203, "uniprot_canonical_ac": "Q8K1Y2-1", "length": 889, "uniprot_id": "KPCD3_MOUSE", "protein_name": "Serine/threonine-protein kinase D3", "refseq_ac": "NP_083515", "refseq_name": "serine/threonine-protein kinase D3 isoform 2", "gene_name": "Prkd3", "gene_names_uniprotkb": "Prkd3; Prkcn", "gene_names_refseq": "4930557O20Rik; 5730497N19Rik; PKD3; Pkcnu; Prkcn; Prkd3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "LKCEGCGLNYHKRCAFKIPN", "down_seq": "CSGVRKRRLSNVSLPGPGLS", "glycosylation": [ { "glytoucan_ac": "G31852PQ", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "IPNNCSGVR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn203", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "42", "end_pos": "42" } ] }, { "type": "snv", "site_list": [ { "start_pos": "42", "end_pos": "42" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "213", "end_pos": "213" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "391", "end_pos": "391" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "41", "end_pos": "41" }, { "start_pos": "426", "end_pos": "426" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "457", "end_pos": "457" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "734", "end_pos": "734" }, { "start_pos": "741", "end_pos": "741" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "upstream", "id": "Q8K1Y2-1.213.213", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q8K1Y2-1.214.214", "categories": [ "glycosylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q8K1Y2-1.216.216", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8K1Y2-1.214.214", "start_pos": 214, "end_pos": 214, "uniprot_canonical_ac": "Q8K1Y2-1", "length": 889, "uniprot_id": "KPCD3_MOUSE", "protein_name": "Serine/threonine-protein kinase D3", "refseq_ac": "NP_083515", "refseq_name": "serine/threonine-protein kinase D3 isoform 2", "gene_name": "Prkd3", "gene_names_uniprotkb": "Prkd3; Prkcn", "gene_names_refseq": "4930557O20Rik; 5730497N19Rik; PKD3; Pkcnu; Prkcn; Prkd3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "KRCAFKIPNNCSGVRKRRLS", "down_seq": "VSLPGPGLSVPRPLQPECVP", "glycosylation": [ { "glytoucan_ac": "G71784JC", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "LSNVSLPGPGLSVPR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn214", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "42", "end_pos": "42" } ] }, { "type": "snv", "site_list": [ { "start_pos": "42", "end_pos": "42" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "213", "end_pos": "213" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "391", "end_pos": "391" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "41", "end_pos": "41" }, { "start_pos": "426", "end_pos": "426" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "457", "end_pos": "457" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "734", "end_pos": "734" }, { "start_pos": "741", "end_pos": "741" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "Q8K1Y2-1.203.203", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q8K1Y2-1.213.213", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q8K1Y2-1.216.216", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8K1Y2-1.42.42", "start_pos": 42, "end_pos": 42, "uniprot_canonical_ac": "Q8K1Y2-1", "length": 889, "uniprot_id": "KPCD3_MOUSE", "protein_name": "Serine/threonine-protein kinase D3", "refseq_ac": "NP_083515", "refseq_name": "serine/threonine-protein kinase D3 isoform 2", "gene_name": "Prkd3", "gene_names_uniprotkb": "Prkd3; Prkcn", "gene_names_refseq": "4930557O20Rik; 5730497N19Rik; PKD3; Pkcnu; Prkcn; Prkd3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "rs3389440054", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389440054", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "VLPAPSPCSSPKTGLSARLS", "down_seq": "GSFSAPSLTNSRGSVHTVSF", "glycosylation": [ { "glytoucan_ac": "G02815KT", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "LSNGSFSAPSLTNSR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn42", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "snv": [ { "evidence": [ { "id": "rs3389440054", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389440054" } ], "glycoeffect": [ "n-glyco-sequon-loss" ], "sequence_org": "N", "sequence_mut": "K", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-loss (NGS->KGS).", "chr_id": "17", "chr_pos": "79320215", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "N42", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "42", "end_pos": "42" } ] }, { "type": "snv", "site_list": [ { "start_pos": "42", "end_pos": "42" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "213", "end_pos": "213" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "391", "end_pos": "391" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "41", "end_pos": "41" }, { "start_pos": "426", "end_pos": "426" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "457", "end_pos": "457" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "734", "end_pos": "734" }, { "start_pos": "741", "end_pos": "741" } ] } ], "categories": [ "glycosylation_flag", "snv_flag" ], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "Q8K1Y2-1.27.27", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q8K1Y2-1.37.37", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q8K1Y2-1.41.41", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q8K1Y2-1.44.44", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8K1Y2-1.213.213", "start_pos": 213, "end_pos": 213, "uniprot_canonical_ac": "Q8K1Y2-1", "length": 889, "uniprot_id": "KPCD3_MOUSE", "protein_name": "Serine/threonine-protein kinase D3", "refseq_ac": "NP_083515", "refseq_name": "serine/threonine-protein kinase D3 isoform 2", "gene_name": "Prkd3", "gene_names_uniprotkb": "Prkd3; Prkcn", "gene_names_refseq": "4930557O20Rik; 5730497N19Rik; PKD3; Pkcnu; Prkcn; Prkd3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2" }, { "database": "iPTMnet", "id": "Q8K1Y2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8K1Y2" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] } ], "crossref": [ { "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8K1Y2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8K1Y2", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "HKRCAFKIPNNCSGVRKRRL", "down_seq": "NVSLPGPGLSVPRPLQPECV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" }, { "database": "iPTMnet", "id": "Q8K1Y2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8K1Y2" } ], "site_lbl": "Ser213" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "42", "end_pos": "42" } ] }, { "type": "snv", "site_list": [ { "start_pos": "42", "end_pos": "42" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "213", "end_pos": "213" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "391", "end_pos": "391" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "41", "end_pos": "41" }, { "start_pos": "426", "end_pos": "426" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "457", "end_pos": "457" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "734", "end_pos": "734" }, { "start_pos": "741", "end_pos": "741" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "Q8K1Y2-1.203.203", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q8K1Y2-1.214.214", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q8K1Y2-1.216.216", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8K1Y2-1.216.216", "start_pos": 216, "end_pos": 216, "uniprot_canonical_ac": "Q8K1Y2-1", "length": 889, "uniprot_id": "KPCD3_MOUSE", "protein_name": "Serine/threonine-protein kinase D3", "refseq_ac": "NP_083515", "refseq_name": "serine/threonine-protein kinase D3 isoform 2", "gene_name": "Prkd3", "gene_names_uniprotkb": "Prkd3; Prkcn", "gene_names_refseq": "4930557O20Rik; 5730497N19Rik; PKD3; Pkcnu; Prkcn; Prkd3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2" }, { "database": "iPTMnet", "id": "Q8K1Y2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8K1Y2" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] } ], "crossref": [ { "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8K1Y2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8K1Y2", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "CAFKIPNNCSGVRKRRLSNV", "down_seq": "LPGPGLSVPRPLQPECVPLL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" }, { "database": "iPTMnet", "id": "Q8K1Y2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8K1Y2" } ], "site_lbl": "Ser216" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "42", "end_pos": "42" } ] }, { "type": "snv", "site_list": [ { "start_pos": "42", "end_pos": "42" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "213", "end_pos": "213" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "391", "end_pos": "391" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "41", "end_pos": "41" }, { "start_pos": "426", "end_pos": "426" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "457", "end_pos": "457" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "734", "end_pos": "734" }, { "start_pos": "741", "end_pos": "741" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "Q8K1Y2-1.203.203", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q8K1Y2-1.213.213", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q8K1Y2-1.214.214", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8K1Y2-1.27.27", "start_pos": 27, "end_pos": 27, "uniprot_canonical_ac": "Q8K1Y2-1", "length": 889, "uniprot_id": "KPCD3_MOUSE", "protein_name": "Serine/threonine-protein kinase D3", "refseq_ac": "NP_083515", "refseq_name": "serine/threonine-protein kinase D3 isoform 2", "gene_name": "Prkd3", "gene_names_uniprotkb": "Prkd3; Prkcn", "gene_names_refseq": "4930557O20Rik; 5730497N19Rik; PKD3; Pkcnu; Prkcn; Prkd3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2" }, { "database": "iPTMnet", "id": "Q8K1Y2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8K1Y2" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8K1Y2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8K1Y2", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PPSAQKSVFPATVSAVLPAP", "down_seq": "PCSSPKTGLSARLSNGSFSA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q8K1Y2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8K1Y2" } ], "site_lbl": "Ser27" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "42", "end_pos": "42" } ] }, { "type": "snv", "site_list": [ { "start_pos": "42", "end_pos": "42" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "213", "end_pos": "213" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "391", "end_pos": "391" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "41", "end_pos": "41" }, { "start_pos": "426", "end_pos": "426" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "457", "end_pos": "457" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "734", "end_pos": "734" }, { "start_pos": "741", "end_pos": "741" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "upstream", "id": "Q8K1Y2-1.37.37", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q8K1Y2-1.41.41", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q8K1Y2-1.42.42", "categories": [ "glycosylation_flag", "snv_flag" ] }, { "distance": 17, "direction": "upstream", "id": "Q8K1Y2-1.44.44", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8K1Y2-1.346.346", "start_pos": 346, "end_pos": 346, "uniprot_canonical_ac": "Q8K1Y2-1", "length": 889, "uniprot_id": "KPCD3_MOUSE", "protein_name": "Serine/threonine-protein kinase D3", "refseq_ac": "NP_083515", "refseq_name": "serine/threonine-protein kinase D3 isoform 2", "gene_name": "Prkd3", "gene_names_uniprotkb": "Prkd3; Prkcn", "gene_names_refseq": "4930557O20Rik; 5730497N19Rik; PKD3; Pkcnu; Prkcn; Prkd3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TFNGEPCSVGTDADMPMDID", "down_seq": "SDVNSDGSRGLDDSEEPSPP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2" } ], "site_lbl": "Ser346" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "42", "end_pos": "42" } ] }, { "type": "snv", "site_list": [ { "start_pos": "42", "end_pos": "42" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "213", "end_pos": "213" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "391", "end_pos": "391" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "41", "end_pos": "41" }, { "start_pos": "426", "end_pos": "426" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "457", "end_pos": "457" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "734", "end_pos": "734" }, { "start_pos": "741", "end_pos": "741" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8K1Y2-1.37.37", "start_pos": 37, "end_pos": 37, "uniprot_canonical_ac": "Q8K1Y2-1", "length": 889, "uniprot_id": "KPCD3_MOUSE", "protein_name": "Serine/threonine-protein kinase D3", "refseq_ac": "NP_083515", "refseq_name": "serine/threonine-protein kinase D3 isoform 2", "gene_name": "Prkd3", "gene_names_uniprotkb": "Prkd3; Prkcn", "gene_names_refseq": "4930557O20Rik; 5730497N19Rik; PKD3; Pkcnu; Prkcn; Prkd3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ATVSAVLPAPSPCSSPKTGL", "down_seq": "ARLSNGSFSAPSLTNSRGSV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2" } ], "site_lbl": "Ser37" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "42", "end_pos": "42" } ] }, { "type": "snv", "site_list": [ { "start_pos": "42", "end_pos": "42" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "213", "end_pos": "213" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "391", "end_pos": "391" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "41", "end_pos": "41" }, { "start_pos": "426", "end_pos": "426" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "457", "end_pos": "457" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "734", "end_pos": "734" }, { "start_pos": "741", "end_pos": "741" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "Q8K1Y2-1.27.27", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q8K1Y2-1.41.41", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q8K1Y2-1.42.42", "categories": [ "glycosylation_flag", "snv_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q8K1Y2-1.44.44", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8K1Y2-1.391.391", "start_pos": 391, "end_pos": 391, "uniprot_canonical_ac": "Q8K1Y2-1", "length": 889, "uniprot_id": "KPCD3_MOUSE", "protein_name": "Serine/threonine-protein kinase D3", "refseq_ac": "NP_083515", "refseq_name": "serine/threonine-protein kinase D3 isoform 2", "gene_name": "Prkd3", "gene_names_uniprotkb": "Prkd3; Prkcn", "gene_names_refseq": "4930557O20Rik; 5730497N19Rik; PKD3; Pkcnu; Prkcn; Prkd3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "FFLDPTDLDVERDEETVKTI", "down_seq": "PSTSNNIPLMRVVQSIKHTK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2" } ], "site_lbl": "Ser391" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "42", "end_pos": "42" } ] }, { "type": "snv", "site_list": [ { "start_pos": "42", "end_pos": "42" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "213", "end_pos": "213" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "391", "end_pos": "391" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "41", "end_pos": "41" }, { "start_pos": "426", "end_pos": "426" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "457", "end_pos": "457" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "734", "end_pos": "734" }, { "start_pos": "741", "end_pos": "741" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "Q8K1Y2-1.395.395", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8K1Y2-1.395.395", "start_pos": 395, "end_pos": 395, "uniprot_canonical_ac": "Q8K1Y2-1", "length": 889, "uniprot_id": "KPCD3_MOUSE", "protein_name": "Serine/threonine-protein kinase D3", "refseq_ac": "NP_083515", "refseq_name": "serine/threonine-protein kinase D3 isoform 2", "gene_name": "Prkd3", "gene_names_uniprotkb": "Prkd3; Prkcn", "gene_names_refseq": "4930557O20Rik; 5730497N19Rik; PKD3; Pkcnu; Prkcn; Prkd3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PTDLDVERDEETVKTISPST", "down_seq": "NNIPLMRVVQSIKHTKRRSS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2" } ], "site_lbl": "Ser395" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "42", "end_pos": "42" } ] }, { "type": "snv", "site_list": [ { "start_pos": "42", "end_pos": "42" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "213", "end_pos": "213" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "391", "end_pos": "391" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "41", "end_pos": "41" }, { "start_pos": "426", "end_pos": "426" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "457", "end_pos": "457" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "734", "end_pos": "734" }, { "start_pos": "741", "end_pos": "741" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "Q8K1Y2-1.391.391", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8K1Y2-1.41.41", "start_pos": 41, "end_pos": 41, "uniprot_canonical_ac": "Q8K1Y2-1", "length": 889, "uniprot_id": "KPCD3_MOUSE", "protein_name": "Serine/threonine-protein kinase D3", "refseq_ac": "NP_083515", "refseq_name": "serine/threonine-protein kinase D3 isoform 2", "gene_name": "Prkd3", "gene_names_uniprotkb": "Prkd3; Prkcn", "gene_names_refseq": "4930557O20Rik; 5730497N19Rik; PKD3; Pkcnu; Prkcn; Prkd3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2" }, { "database": "iPTMnet", "id": "Q8K1Y2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8K1Y2" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8K1Y2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8K1Y2", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AVLPAPSPCSSPKTGLSARL", "down_seq": "NGSFSAPSLTNSRGSVHTVS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q8K1Y2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8K1Y2" } ], "site_lbl": "Ser41" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "42", "end_pos": "42" } ] }, { "type": "snv", "site_list": [ { "start_pos": "42", "end_pos": "42" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "213", "end_pos": "213" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "391", "end_pos": "391" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "41", "end_pos": "41" }, { "start_pos": "426", "end_pos": "426" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "457", "end_pos": "457" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "734", "end_pos": "734" }, { "start_pos": "741", "end_pos": "741" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "Q8K1Y2-1.27.27", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q8K1Y2-1.37.37", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q8K1Y2-1.42.42", "categories": [ "glycosylation_flag", "snv_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q8K1Y2-1.44.44", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8K1Y2-1.426.426", "start_pos": 426, "end_pos": 426, "uniprot_canonical_ac": "Q8K1Y2-1", "length": 889, "uniprot_id": "KPCD3_MOUSE", "protein_name": "Serine/threonine-protein kinase D3", "refseq_ac": "NP_083515", "refseq_name": "serine/threonine-protein kinase D3 isoform 2", "gene_name": "Prkd3", "gene_names_uniprotkb": "Prkd3; Prkcn", "gene_names_refseq": "4930557O20Rik; 5730497N19Rik; PKD3; Pkcnu; Prkcn; Prkd3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "SIKHTKRRSSTVVKEGWMVH", "down_seq": "TSRDNLRKRHYWRLDSKCLT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2" } ], "site_lbl": "Tyr426" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "42", "end_pos": "42" } ] }, { "type": "snv", "site_list": [ { "start_pos": "42", "end_pos": "42" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "213", "end_pos": "213" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "391", "end_pos": "391" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "41", "end_pos": "41" }, { "start_pos": "426", "end_pos": "426" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "457", "end_pos": "457" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "734", "end_pos": "734" }, { "start_pos": "741", "end_pos": "741" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "upstream", "id": "Q8K1Y2-1.442.442", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8K1Y2-1.442.442", "start_pos": 442, "end_pos": 442, "uniprot_canonical_ac": "Q8K1Y2-1", "length": 889, "uniprot_id": "KPCD3_MOUSE", "protein_name": "Serine/threonine-protein kinase D3", "refseq_ac": "NP_083515", "refseq_name": "serine/threonine-protein kinase D3 isoform 2", "gene_name": "Prkd3", "gene_names_uniprotkb": "Prkd3; Prkcn", "gene_names_refseq": "4930557O20Rik; 5730497N19Rik; PKD3; Pkcnu; Prkcn; Prkd3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "WMVHYTSRDNLRKRHYWRLD", "down_seq": "KCLTLFQNESGSKYYKEIPL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2" } ], "site_lbl": "Ser442" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "42", "end_pos": "42" } ] }, { "type": "snv", "site_list": [ { "start_pos": "42", "end_pos": "42" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "213", "end_pos": "213" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "391", "end_pos": "391" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "41", "end_pos": "41" }, { "start_pos": "426", "end_pos": "426" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "457", "end_pos": "457" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "734", "end_pos": "734" }, { "start_pos": "741", "end_pos": "741" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "Q8K1Y2-1.426.426", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q8K1Y2-1.457.457", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8K1Y2-1.44.44", "start_pos": 44, "end_pos": 44, "uniprot_canonical_ac": "Q8K1Y2-1", "length": 889, "uniprot_id": "KPCD3_MOUSE", "protein_name": "Serine/threonine-protein kinase D3", "refseq_ac": "NP_083515", "refseq_name": "serine/threonine-protein kinase D3 isoform 2", "gene_name": "Prkd3", "gene_names_uniprotkb": "Prkd3; Prkcn", "gene_names_refseq": "4930557O20Rik; 5730497N19Rik; PKD3; Pkcnu; Prkcn; Prkd3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2" }, { "database": "iPTMnet", "id": "Q8K1Y2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8K1Y2" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8K1Y2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8K1Y2", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PAPSPCSSPKTGLSARLSNG", "down_seq": "FSAPSLTNSRGSVHTVSFLL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q8K1Y2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8K1Y2" } ], "site_lbl": "Ser44" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "42", "end_pos": "42" } ] }, { "type": "snv", "site_list": [ { "start_pos": "42", "end_pos": "42" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "213", "end_pos": "213" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "391", "end_pos": "391" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "41", "end_pos": "41" }, { "start_pos": "426", "end_pos": "426" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "457", "end_pos": "457" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "734", "end_pos": "734" }, { "start_pos": "741", "end_pos": "741" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "Q8K1Y2-1.27.27", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "Q8K1Y2-1.37.37", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q8K1Y2-1.41.41", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q8K1Y2-1.42.42", "categories": [ "glycosylation_flag", "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8K1Y2-1.457.457", "start_pos": 457, "end_pos": 457, "uniprot_canonical_ac": "Q8K1Y2-1", "length": 889, "uniprot_id": "KPCD3_MOUSE", "protein_name": "Serine/threonine-protein kinase D3", "refseq_ac": "NP_083515", "refseq_name": "serine/threonine-protein kinase D3 isoform 2", "gene_name": "Prkd3", "gene_names_uniprotkb": "Prkd3; Prkcn", "gene_names_refseq": "4930557O20Rik; 5730497N19Rik; PKD3; Pkcnu; Prkcn; Prkd3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "YWRLDSKCLTLFQNESGSKY", "down_seq": "KEIPLSEILRVSSPQDFTSI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2" } ], "site_lbl": "Tyr457" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "42", "end_pos": "42" } ] }, { "type": "snv", "site_list": [ { "start_pos": "42", "end_pos": "42" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "213", "end_pos": "213" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "391", "end_pos": "391" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "41", "end_pos": "41" }, { "start_pos": "426", "end_pos": "426" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "457", "end_pos": "457" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "734", "end_pos": "734" }, { "start_pos": "741", "end_pos": "741" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "Q8K1Y2-1.442.442", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8K1Y2-1.535.535", "start_pos": 535, "end_pos": 535, "uniprot_canonical_ac": "Q8K1Y2-1", "length": 889, "uniprot_id": "KPCD3_MOUSE", "protein_name": "Serine/threonine-protein kinase D3", "refseq_ac": "NP_083515", "refseq_name": "serine/threonine-protein kinase D3 isoform 2", "gene_name": "Prkd3", "gene_names_uniprotkb": "Prkd3; Prkcn", "gene_names_refseq": "4930557O20Rik; 5730497N19Rik; PKD3; Pkcnu; Prkcn; Prkd3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2" }, { "database": "iPTMnet", "id": "Q8K1Y2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8K1Y2" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8K1Y2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8K1Y2", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "VGLDVAQSWEKAIRQALMPV", "down_seq": "PQASVCTSPGQGKDHNLATS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q8K1Y2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8K1Y2" } ], "site_lbl": "Thr535" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "42", "end_pos": "42" } ] }, { "type": "snv", "site_list": [ { "start_pos": "42", "end_pos": "42" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "213", "end_pos": "213" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "391", "end_pos": "391" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "41", "end_pos": "41" }, { "start_pos": "426", "end_pos": "426" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "457", "end_pos": "457" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "734", "end_pos": "734" }, { "start_pos": "741", "end_pos": "741" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "Q8K1Y2-1.539.539", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8K1Y2-1.539.539", "start_pos": 539, "end_pos": 539, "uniprot_canonical_ac": "Q8K1Y2-1", "length": 889, "uniprot_id": "KPCD3_MOUSE", "protein_name": "Serine/threonine-protein kinase D3", "refseq_ac": "NP_083515", "refseq_name": "serine/threonine-protein kinase D3 isoform 2", "gene_name": "Prkd3", "gene_names_uniprotkb": "Prkd3; Prkcn", "gene_names_refseq": "4930557O20Rik; 5730497N19Rik; PKD3; Pkcnu; Prkcn; Prkd3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2" }, { "database": "iPTMnet", "id": "Q8K1Y2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8K1Y2" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8K1Y2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8K1Y2", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VAQSWEKAIRQALMPVTPQA", "down_seq": "VCTSPGQGKDHNLATSISVS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q8K1Y2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8K1Y2" } ], "site_lbl": "Ser539" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "42", "end_pos": "42" } ] }, { "type": "snv", "site_list": [ { "start_pos": "42", "end_pos": "42" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "213", "end_pos": "213" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "391", "end_pos": "391" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "41", "end_pos": "41" }, { "start_pos": "426", "end_pos": "426" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "457", "end_pos": "457" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "734", "end_pos": "734" }, { "start_pos": "741", "end_pos": "741" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "Q8K1Y2-1.535.535", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8K1Y2-1.730.730", "start_pos": 730, "end_pos": 730, "uniprot_canonical_ac": "Q8K1Y2-1", "length": 889, "uniprot_id": "KPCD3_MOUSE", "protein_name": "Serine/threonine-protein kinase D3", "refseq_ac": "NP_083515", "refseq_name": "serine/threonine-protein kinase D3 isoform 2", "gene_name": "Prkd3", "gene_names_uniprotkb": "Prkd3; Prkcn", "gene_names_refseq": "4930557O20Rik; 5730497N19Rik; PKD3; Pkcnu; Prkcn; Prkd3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EPFPQVKLCDFGFARIIGEK", "down_seq": "FRRSVVGTPAYLAPEVLRSK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by PKC", "evidence": [ { "database": "UniProtKB", "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2" } ], "site_lbl": "Ser730" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "42", "end_pos": "42" } ] }, { "type": "snv", "site_list": [ { "start_pos": "42", "end_pos": "42" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "213", "end_pos": "213" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "391", "end_pos": "391" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "41", "end_pos": "41" }, { "start_pos": "426", "end_pos": "426" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "457", "end_pos": "457" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "734", "end_pos": "734" }, { "start_pos": "741", "end_pos": "741" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "Q8K1Y2-1.734.734", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q8K1Y2-1.741.741", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8K1Y2-1.734.734", "start_pos": 734, "end_pos": 734, "uniprot_canonical_ac": "Q8K1Y2-1", "length": 889, "uniprot_id": "KPCD3_MOUSE", "protein_name": "Serine/threonine-protein kinase D3", "refseq_ac": "NP_083515", "refseq_name": "serine/threonine-protein kinase D3 isoform 2", "gene_name": "Prkd3", "gene_names_uniprotkb": "Prkd3; Prkcn", "gene_names_refseq": "4930557O20Rik; 5730497N19Rik; PKD3; Pkcnu; Prkcn; Prkd3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QVKLCDFGFARIIGEKSFRR", "down_seq": "VVGTPAYLAPEVLRSKGYNR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by autocatalysis", "evidence": [ { "database": "UniProtKB", "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2" } ], "site_lbl": "Ser734" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "42", "end_pos": "42" } ] }, { "type": "snv", "site_list": [ { "start_pos": "42", "end_pos": "42" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "213", "end_pos": "213" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "391", "end_pos": "391" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "41", "end_pos": "41" }, { "start_pos": "426", "end_pos": "426" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "457", "end_pos": "457" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "734", "end_pos": "734" }, { "start_pos": "741", "end_pos": "741" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "Q8K1Y2-1.730.730", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q8K1Y2-1.741.741", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8K1Y2-1.741.741", "start_pos": 741, "end_pos": 741, "uniprot_canonical_ac": "Q8K1Y2-1", "length": 889, "uniprot_id": "KPCD3_MOUSE", "protein_name": "Serine/threonine-protein kinase D3", "refseq_ac": "NP_083515", "refseq_name": "serine/threonine-protein kinase D3 isoform 2", "gene_name": "Prkd3", "gene_names_uniprotkb": "Prkd3; Prkcn", "gene_names_refseq": "4930557O20Rik; 5730497N19Rik; PKD3; Pkcnu; Prkcn; Prkd3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "GFARIIGEKSFRRSVVGTPA", "down_seq": "LAPEVLRSKGYNRSLDMWSV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "Q8K1Y2", "url": "https://www.uniprot.org/uniprotkb/Q8K1Y2" } ], "site_lbl": "Tyr741" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "42", "end_pos": "42" } ] }, { "type": "snv", "site_list": [ { "start_pos": "42", "end_pos": "42" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "213", "end_pos": "213" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "391", "end_pos": "391" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "41", "end_pos": "41" }, { "start_pos": "426", "end_pos": "426" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "457", "end_pos": "457" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "734", "end_pos": "734" }, { "start_pos": "741", "end_pos": "741" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "Q8K1Y2-1.730.730", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "Q8K1Y2-1.734.734", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q52KR2-1.1024.1024", "start_pos": 1024, "end_pos": 1024, "uniprot_canonical_ac": "Q52KR2-1", "length": 1054, "uniprot_id": "LRIG2_MOUSE", "protein_name": "Leucine-rich repeats and immunoglobulin-like domains protein 2", "refseq_ac": "NP_001020238", "refseq_name": "leucine-rich repeats and immunoglobulin-like domains protein 2 isoform 1 precursor", "gene_name": "Lrig2", "gene_names_uniprotkb": "Lrig2; Kiaa0806", "gene_names_refseq": "4632419I10Rik; LIG-2; Lrig2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q52KR2", "url": "https://www.uniprot.org/uniprotkb/Q52KR2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "Q52KR2", "url": "https://www.uniprot.org/uniprotkb/Q52KR2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "LLPFSQQPVLESPELTERDP", "down_seq": "CSSPVTCRRLHDHAFDFSRT", "glycosylation": [ { "glytoucan_ac": "G02815KT", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "DPNCSSPVTCRR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1024", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1024", "evidence": [ { "id": "Q52KR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q52KR2#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1024", "end_pos": "1024" }, { "start_pos": "120", "end_pos": "120" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "467", "end_pos": "467" }, { "start_pos": "513", "end_pos": "513" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "90", "end_pos": "90" } ] }, { "type": "snv", "site_list": [ { "start_pos": "174", "end_pos": "174" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "570", "end_pos": "570" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "905", "end_pos": "905" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q52KR2-1.120.120", "start_pos": 120, "end_pos": 120, "uniprot_canonical_ac": "Q52KR2-1", "length": 1054, "uniprot_id": "LRIG2_MOUSE", "protein_name": "Leucine-rich repeats and immunoglobulin-like domains protein 2", "refseq_ac": "NP_001020238", "refseq_name": "leucine-rich repeats and immunoglobulin-like domains protein 2 isoform 1 precursor", "gene_name": "Lrig2", "gene_names_uniprotkb": "Lrig2; Kiaa0806", "gene_names_refseq": "4632419I10Rik; LIG-2; Lrig2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q52KR2", "url": "https://www.uniprot.org/uniprotkb/Q52KR2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q52KR2", "url": "https://www.uniprot.org/uniprotkb/Q52KR2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "EVKMNYNELTEIPYFGEPTP", "down_seq": "ITLLSLVHNLIPEINAEAFE", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn120", "evidence": [ { "id": "Q52KR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q52KR2#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1024", "end_pos": "1024" }, { "start_pos": "120", "end_pos": "120" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "467", "end_pos": "467" }, { "start_pos": "513", "end_pos": "513" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "90", "end_pos": "90" } ] }, { "type": "snv", "site_list": [ { "start_pos": "174", "end_pos": "174" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "570", "end_pos": "570" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "905", "end_pos": "905" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q52KR2-1.172.172", "start_pos": 172, "end_pos": 172, "uniprot_canonical_ac": "Q52KR2-1", "length": 1054, "uniprot_id": "LRIG2_MOUSE", "protein_name": "Leucine-rich repeats and immunoglobulin-like domains protein 2", "refseq_ac": "NP_001020238", "refseq_name": "leucine-rich repeats and immunoglobulin-like domains protein 2 isoform 1 precursor", "gene_name": "Lrig2", "gene_names_uniprotkb": "Lrig2; Kiaa0806", "gene_names_refseq": "4632419I10Rik; LIG-2; Lrig2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q52KR2", "url": "https://www.uniprot.org/uniprotkb/Q52KR2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "Q52KR2", "url": "https://www.uniprot.org/uniprotkb/Q52KR2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "SNIISEIKTSSFPRMSLKYL", "down_seq": "LSNNRISTLEAGCFDNLSDS", "glycosylation": [ { "glytoucan_ac": "G80920RR", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "YLNLSNNR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn172", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn172", "evidence": [ { "id": "Q52KR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q52KR2#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1024", "end_pos": "1024" }, { "start_pos": "120", "end_pos": "120" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "467", "end_pos": "467" }, { "start_pos": "513", "end_pos": "513" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "90", "end_pos": "90" } ] }, { "type": "snv", "site_list": [ { "start_pos": "174", "end_pos": "174" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "570", "end_pos": "570" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "905", "end_pos": "905" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "Q52KR2-1.174.174", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q52KR2-1.188.188", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q52KR2-1.188.188", "start_pos": 188, "end_pos": 188, "uniprot_canonical_ac": "Q52KR2-1", "length": 1054, "uniprot_id": "LRIG2_MOUSE", "protein_name": "Leucine-rich repeats and immunoglobulin-like domains protein 2", "refseq_ac": "NP_001020238", "refseq_name": "leucine-rich repeats and immunoglobulin-like domains protein 2 isoform 1 precursor", "gene_name": "Lrig2", "gene_names_uniprotkb": "Lrig2; Kiaa0806", "gene_names_refseq": "4632419I10Rik; LIG-2; Lrig2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q52KR2", "url": "https://www.uniprot.org/uniprotkb/Q52KR2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "Q52KR2", "url": "https://www.uniprot.org/uniprotkb/Q52KR2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "LKYLNLSNNRISTLEAGCFD", "down_seq": "LSDSLLVVKLNRNRISMIPP", "glycosylation": [ { "glytoucan_ac": "G80920RR", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "ISTLEAGCFDNLSDSLLVVK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn188", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn188", "evidence": [ { "id": "Q52KR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q52KR2#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1024", "end_pos": "1024" }, { "start_pos": "120", "end_pos": "120" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "467", "end_pos": "467" }, { "start_pos": "513", "end_pos": "513" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "90", "end_pos": "90" } ] }, { "type": "snv", "site_list": [ { "start_pos": "174", "end_pos": "174" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "570", "end_pos": "570" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "905", "end_pos": "905" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "Q52KR2-1.172.172", "categories": [ "glycosylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "Q52KR2-1.174.174", "categories": [ "snv_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q52KR2-1.273.273", "start_pos": 273, "end_pos": 273, "uniprot_canonical_ac": "Q52KR2-1", "length": 1054, "uniprot_id": "LRIG2_MOUSE", "protein_name": "Leucine-rich repeats and immunoglobulin-like domains protein 2", "refseq_ac": "NP_001020238", "refseq_name": "leucine-rich repeats and immunoglobulin-like domains protein 2 isoform 1 precursor", "gene_name": "Lrig2", "gene_names_uniprotkb": "Lrig2; Kiaa0806", "gene_names_refseq": "4632419I10Rik; LIG-2; Lrig2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q52KR2", "url": "https://www.uniprot.org/uniprotkb/Q52KR2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "Q52KR2", "url": "https://www.uniprot.org/uniprotkb/Q52KR2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "LKDGAFFGLNNMEELELEHN", "down_seq": "LTGVNKGWLYGLRMLQQLYM", "glycosylation": [ { "glytoucan_ac": "G80920RR", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "DGAFFGLNNMEELELEHNNLTGVNK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn273", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn273", "evidence": [ { "id": "Q52KR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q52KR2#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1024", "end_pos": "1024" }, { "start_pos": "120", "end_pos": "120" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "467", "end_pos": "467" }, { "start_pos": "513", "end_pos": "513" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "90", "end_pos": "90" } ] }, { "type": "snv", "site_list": [ { "start_pos": "174", "end_pos": "174" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "570", "end_pos": "570" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "905", "end_pos": "905" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q52KR2-1.440.440", "start_pos": 440, "end_pos": 440, "uniprot_canonical_ac": "Q52KR2-1", "length": 1054, "uniprot_id": "LRIG2_MOUSE", "protein_name": "Leucine-rich repeats and immunoglobulin-like domains protein 2", "refseq_ac": "NP_001020238", "refseq_name": "leucine-rich repeats and immunoglobulin-like domains protein 2 isoform 1 precursor", "gene_name": "Lrig2", "gene_names_uniprotkb": "Lrig2; Kiaa0806", "gene_names_refseq": "4632419I10Rik; LIG-2; Lrig2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q52KR2", "url": "https://www.uniprot.org/uniprotkb/Q52KR2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "Q52KR2", "url": "https://www.uniprot.org/uniprotkb/Q52KR2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "AIMSIQENAFSQTHLKGLVL", "down_seq": "TSSLLCDCHLKWLLQWLVDN", "glycosylation": [ { "glytoucan_ac": "G83460ZZ", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "GLVLNTSSLLCDCHLK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn440", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn440", "evidence": [ { "id": "Q52KR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q52KR2#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1024", "end_pos": "1024" }, { "start_pos": "120", "end_pos": "120" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "467", "end_pos": "467" }, { "start_pos": "513", "end_pos": "513" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "90", "end_pos": "90" } ] }, { "type": "snv", "site_list": [ { "start_pos": "174", "end_pos": "174" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "570", "end_pos": "570" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "905", "end_pos": "905" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "Q52KR2-1.420.420", "categories": [ "snv_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q52KR2-1.467.467", "start_pos": 467, "end_pos": 467, "uniprot_canonical_ac": "Q52KR2-1", "length": 1054, "uniprot_id": "LRIG2_MOUSE", "protein_name": "Leucine-rich repeats and immunoglobulin-like domains protein 2", "refseq_ac": "NP_001020238", "refseq_name": "leucine-rich repeats and immunoglobulin-like domains protein 2 isoform 1 precursor", "gene_name": "Lrig2", "gene_names_uniprotkb": "Lrig2; Kiaa0806", "gene_names_refseq": "4632419I10Rik; LIG-2; Lrig2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q52KR2", "url": "https://www.uniprot.org/uniprotkb/Q52KR2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q52KR2", "url": "https://www.uniprot.org/uniprotkb/Q52KR2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "DCHLKWLLQWLVDNNFHHSV", "down_seq": "VSCAHPEWLAGQSILNVDLK", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn467", "evidence": [ { "id": "Q52KR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q52KR2#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1024", "end_pos": "1024" }, { "start_pos": "120", "end_pos": "120" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "467", "end_pos": "467" }, { "start_pos": "513", "end_pos": "513" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "90", "end_pos": "90" } ] }, { "type": "snv", "site_list": [ { "start_pos": "174", "end_pos": "174" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "570", "end_pos": "570" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "905", "end_pos": "905" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q52KR2-1.513.513", "start_pos": 513, "end_pos": 513, "uniprot_canonical_ac": "Q52KR2-1", "length": 1054, "uniprot_id": "LRIG2_MOUSE", "protein_name": "Leucine-rich repeats and immunoglobulin-like domains protein 2", "refseq_ac": "NP_001020238", "refseq_name": "leucine-rich repeats and immunoglobulin-like domains protein 2 isoform 1 precursor", "gene_name": "Lrig2", "gene_names_uniprotkb": "Lrig2; Kiaa0806", "gene_names_refseq": "4632419I10Rik; LIG-2; Lrig2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q52KR2", "url": "https://www.uniprot.org/uniprotkb/Q52KR2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q52KR2", "url": "https://www.uniprot.org/uniprotkb/Q52KR2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "DFLKPQIRTHPESTIALRGV", "down_seq": "VTLTCTAVSSSDSPMSTIWR", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn513", "evidence": [ { "id": "Q52KR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q52KR2#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1024", "end_pos": "1024" }, { "start_pos": "120", "end_pos": "120" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "467", "end_pos": "467" }, { "start_pos": "513", "end_pos": "513" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "90", "end_pos": "90" } ] }, { "type": "snv", "site_list": [ { "start_pos": "174", "end_pos": "174" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "570", "end_pos": "570" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "905", "end_pos": "905" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q52KR2-1.570.570", "start_pos": 570, "end_pos": 570, "uniprot_canonical_ac": "Q52KR2-1", "length": 1054, "uniprot_id": "LRIG2_MOUSE", "protein_name": "Leucine-rich repeats and immunoglobulin-like domains protein 2", "refseq_ac": "NP_001020238", "refseq_name": "leucine-rich repeats and immunoglobulin-like domains protein 2 isoform 1 precursor", "gene_name": "Lrig2", "gene_names_uniprotkb": "Lrig2; Kiaa0806", "gene_names_refseq": "4632419I10Rik; LIG-2; Lrig2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q52KR2", "url": "https://www.uniprot.org/uniprotkb/Q52KR2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "Q52KR2", "url": "https://www.uniprot.org/uniprotkb/Q52KR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "rs3388651433", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388651433", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "YRQQDGEALEYTSVLRLFSV", "down_seq": "FTDEGKYQCIVTNHFGSNYS", "glycosylation": [ { "glytoucan_ac": "G62765YT", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "LFSVNFTDEGK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn570", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn570", "evidence": [ { "id": "Q52KR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q52KR2#ptm_processing" } ] } ], "snv": [ { "evidence": [ { "id": "rs3388651433", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388651433" } ], "glycoeffect": [ "n-glyco-sequon-loss" ], "sequence_org": "N", "sequence_mut": "S", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-loss (NFT->SFT).", "chr_id": "3", "chr_pos": "104374445", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "N570", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1024", "end_pos": "1024" }, { "start_pos": "120", "end_pos": "120" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "467", "end_pos": "467" }, { "start_pos": "513", "end_pos": "513" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "90", "end_pos": "90" } ] }, { "type": "snv", "site_list": [ { "start_pos": "174", "end_pos": "174" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "570", "end_pos": "570" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "905", "end_pos": "905" } ] } ], "categories": [ "glycosylation_flag", "snv_flag" ], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "upstream", "id": "Q52KR2-1.588.588", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q52KR2-1.588.588", "start_pos": 588, "end_pos": 588, "uniprot_canonical_ac": "Q52KR2-1", "length": 1054, "uniprot_id": "LRIG2_MOUSE", "protein_name": "Leucine-rich repeats and immunoglobulin-like domains protein 2", "refseq_ac": "NP_001020238", "refseq_name": "leucine-rich repeats and immunoglobulin-like domains protein 2 isoform 1 precursor", "gene_name": "Lrig2", "gene_names_uniprotkb": "Lrig2; Kiaa0806", "gene_names_refseq": "4632419I10Rik; LIG-2; Lrig2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q52KR2", "url": "https://www.uniprot.org/uniprotkb/Q52KR2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "Q52KR2", "url": "https://www.uniprot.org/uniprotkb/Q52KR2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "SVNFTDEGKYQCIVTNHFGS", "down_seq": "YSQKAKLTVNEMPSFLKTPM", "glycosylation": [ { "glytoucan_ac": "G80920RR", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "YQCIVTNHFGSNYSQK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn588", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn588", "evidence": [ { "id": "Q52KR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q52KR2#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1024", "end_pos": "1024" }, { "start_pos": "120", "end_pos": "120" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "467", "end_pos": "467" }, { "start_pos": "513", "end_pos": "513" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "90", "end_pos": "90" } ] }, { "type": "snv", "site_list": [ { "start_pos": "174", "end_pos": "174" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "570", "end_pos": "570" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "905", "end_pos": "905" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "Q52KR2-1.570.570", "categories": [ "glycosylation_flag", "snv_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q52KR2-1.686.686", "start_pos": 686, "end_pos": 686, "uniprot_canonical_ac": "Q52KR2-1", "length": 1054, "uniprot_id": "LRIG2_MOUSE", "protein_name": "Leucine-rich repeats and immunoglobulin-like domains protein 2", "refseq_ac": "NP_001020238", "refseq_name": "leucine-rich repeats and immunoglobulin-like domains protein 2 isoform 1 precursor", "gene_name": "Lrig2", "gene_names_uniprotkb": "Lrig2; Kiaa0806", "gene_names_refseq": "4632419I10Rik; LIG-2; Lrig2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q52KR2", "url": "https://www.uniprot.org/uniprotkb/Q52KR2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q52KR2", "url": "https://www.uniprot.org/uniprotkb/Q52KR2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "IEDMGIYSCMAQNIAGGLSA", "down_seq": "ASLTVLETPSFIRPLEDKTV", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn686", "evidence": [ { "id": "Q52KR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q52KR2#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1024", "end_pos": "1024" }, { "start_pos": "120", "end_pos": "120" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "467", "end_pos": "467" }, { "start_pos": "513", "end_pos": "513" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "90", "end_pos": "90" } ] }, { "type": "snv", "site_list": [ { "start_pos": "174", "end_pos": "174" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "570", "end_pos": "570" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "905", "end_pos": "905" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q52KR2-1.727.727", "start_pos": 727, "end_pos": 727, "uniprot_canonical_ac": "Q52KR2-1", "length": 1054, "uniprot_id": "LRIG2_MOUSE", "protein_name": "Leucine-rich repeats and immunoglobulin-like domains protein 2", "refseq_ac": "NP_001020238", "refseq_name": "leucine-rich repeats and immunoglobulin-like domains protein 2 isoform 1 precursor", "gene_name": "Lrig2", "gene_names_uniprotkb": "Lrig2; Kiaa0806", "gene_names_refseq": "4632419I10Rik; LIG-2; Lrig2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q52KR2", "url": "https://www.uniprot.org/uniprotkb/Q52KR2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "Q52KR2", "url": "https://www.uniprot.org/uniprotkb/Q52KR2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "TRGETAVLQCIAGGSPAPRL", "down_seq": "WTKDDGPLLVTERHFFAAAN", "glycosylation": [ { "glytoucan_ac": "G80920RR", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "LNWTKDDGPLLVTER", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn727", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn727", "evidence": [ { "id": "Q52KR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q52KR2#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1024", "end_pos": "1024" }, { "start_pos": "120", "end_pos": "120" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "467", "end_pos": "467" }, { "start_pos": "513", "end_pos": "513" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "90", "end_pos": "90" } ] }, { "type": "snv", "site_list": [ { "start_pos": "174", "end_pos": "174" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "570", "end_pos": "570" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "905", "end_pos": "905" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q52KR2-1.90.90", "start_pos": 90, "end_pos": 90, "uniprot_canonical_ac": "Q52KR2-1", "length": 1054, "uniprot_id": "LRIG2_MOUSE", "protein_name": "Leucine-rich repeats and immunoglobulin-like domains protein 2", "refseq_ac": "NP_001020238", "refseq_name": "leucine-rich repeats and immunoglobulin-like domains protein 2 isoform 1 precursor", "gene_name": "Lrig2", "gene_names_uniprotkb": "Lrig2; Kiaa0806", "gene_names_refseq": "4632419I10Rik; LIG-2; Lrig2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q52KR2", "url": "https://www.uniprot.org/uniprotkb/Q52KR2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "Q52KR2", "url": "https://www.uniprot.org/uniprotkb/Q52KR2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "GPLPSDISSLDLSHNRLSNW", "down_seq": "NTLESQTLQEVKMNYNELTE", "glycosylation": [ { "glytoucan_ac": "G25079LO", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "LSNWNNTLESQTLQEVK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn90", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn90", "evidence": [ { "id": "Q52KR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q52KR2#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1024", "end_pos": "1024" }, { "start_pos": "120", "end_pos": "120" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "467", "end_pos": "467" }, { "start_pos": "513", "end_pos": "513" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "90", "end_pos": "90" } ] }, { "type": "snv", "site_list": [ { "start_pos": "174", "end_pos": "174" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "570", "end_pos": "570" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "905", "end_pos": "905" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q52KR2-1.174.174", "start_pos": 174, "end_pos": 174, "uniprot_canonical_ac": "Q52KR2-1", "length": 1054, "uniprot_id": "LRIG2_MOUSE", "protein_name": "Leucine-rich repeats and immunoglobulin-like domains protein 2", "refseq_ac": "NP_001020238", "refseq_name": "leucine-rich repeats and immunoglobulin-like domains protein 2 isoform 1 precursor", "gene_name": "Lrig2", "gene_names_uniprotkb": "Lrig2; Kiaa0806", "gene_names_refseq": "4632419I10Rik; LIG-2; Lrig2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q52KR2", "url": "https://www.uniprot.org/uniprotkb/Q52KR2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs33580428", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs33580428", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "IISEIKTSSFPRMSLKYLNL", "down_seq": "NNRISTLEAGCFDNLSDSLL", "snv": [ { "evidence": [ { "id": "rs33580428", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs33580428" } ], "glycoeffect": [ "n-glyco-sequon-loss", "o-glyco-site-loss" ], "sequence_org": "S", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-loss (NLS->NLN).", "chr_id": "3", "chr_pos": "104399140", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S174", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1024", "end_pos": "1024" }, { "start_pos": "120", "end_pos": "120" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "467", "end_pos": "467" }, { "start_pos": "513", "end_pos": "513" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "90", "end_pos": "90" } ] }, { "type": "snv", "site_list": [ { "start_pos": "174", "end_pos": "174" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "570", "end_pos": "570" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "905", "end_pos": "905" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "Q52KR2-1.172.172", "categories": [ "glycosylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q52KR2-1.188.188", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q52KR2-1.420.420", "start_pos": 420, "end_pos": 420, "uniprot_canonical_ac": "Q52KR2-1", "length": 1054, "uniprot_id": "LRIG2_MOUSE", "protein_name": "Leucine-rich repeats and immunoglobulin-like domains protein 2", "refseq_ac": "NP_001020238", "refseq_name": "leucine-rich repeats and immunoglobulin-like domains protein 2 isoform 1 precursor", "gene_name": "Lrig2", "gene_names_uniprotkb": "Lrig2; Kiaa0806", "gene_names_refseq": "4632419I10Rik; LIG-2; Lrig2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q52KR2", "url": "https://www.uniprot.org/uniprotkb/Q52KR2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388659181", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388659181", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "A", "start_aa": "A", "up_seq": "VTQKAFIGLESLEYLDLNNN", "down_seq": "IMSIQENAFSQTHLKGLVLN", "snv": [ { "evidence": [ { "id": "rs3388659181", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388659181" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "A", "sequence_mut": "S", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (NNA->NNS).", "chr_id": "3", "chr_pos": "104387150", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "A420", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1024", "end_pos": "1024" }, { "start_pos": "120", "end_pos": "120" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "467", "end_pos": "467" }, { "start_pos": "513", "end_pos": "513" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "90", "end_pos": "90" } ] }, { "type": "snv", "site_list": [ { "start_pos": "174", "end_pos": "174" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "570", "end_pos": "570" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "905", "end_pos": "905" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "upstream", "id": "Q52KR2-1.440.440", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q52KR2-1.905.905", "start_pos": 905, "end_pos": 905, "uniprot_canonical_ac": "Q52KR2-1", "length": 1054, "uniprot_id": "LRIG2_MOUSE", "protein_name": "Leucine-rich repeats and immunoglobulin-like domains protein 2", "refseq_ac": "NP_001020238", "refseq_name": "leucine-rich repeats and immunoglobulin-like domains protein 2 isoform 1 precursor", "gene_name": "Lrig2", "gene_names_uniprotkb": "Lrig2; Kiaa0806", "gene_names_refseq": "4632419I10Rik; LIG-2; Lrig2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q52KR2", "url": "https://www.uniprot.org/uniprotkb/Q52KR2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.", "journal": "Nature biotechnology", "date": "2005", "authors": "Rush J, Moritz A, Lee KA, Guo A, Goss VL, Spek EJ, Zhang H, Zha XM, Polakiewicz RD, Comb MJ", "evidence": [ { "database": "UniProtKB", "id": "Q52KR2", "url": "https://www.uniprot.org/uniprotkb/Q52KR2" }, { "database": "iPTMnet", "id": "Q52KR2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q52KR2" } ], "reference": [ { "type": "PubMed", "id": "15592455", "url": "https://glygen.org/publication/PubMed/15592455" } ] } ], "crossref": [ { "id": "Q52KR2", "url": "https://www.uniprot.org/uniprotkb/Q52KR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "15592455", "url": "https://glygen.org/publication/PubMed/15592455", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q52KR2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q52KR2", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "GYTHRGTDGGAGTRVICSDC", "down_seq": "DNANIYSRTREYCPYTYIAE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "Q52KR2", "url": "https://www.uniprot.org/uniprotkb/Q52KR2" }, { "database": "PubMed", "id": "15592455", "url": "https://glygen.org/publication/PubMed/15592455" }, { "database": "iPTMnet", "id": "Q52KR2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q52KR2" } ], "site_lbl": "Tyr905" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1024", "end_pos": "1024" }, { "start_pos": "120", "end_pos": "120" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "467", "end_pos": "467" }, { "start_pos": "513", "end_pos": "513" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "727", "end_pos": "727" }, { "start_pos": "90", "end_pos": "90" } ] }, { "type": "snv", "site_list": [ { "start_pos": "174", "end_pos": "174" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "570", "end_pos": "570" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "905", "end_pos": "905" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D1T0-1.138.138", "start_pos": 138, "end_pos": 138, "uniprot_canonical_ac": "Q9D1T0-1", "length": 614, "uniprot_id": "LIGO1_MOUSE", "protein_name": "Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1", "refseq_ac": "NP_001298005", "refseq_name": "leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 isoform 1 precursor", "gene_name": "Lingo1", "gene_names_uniprotkb": "Lingo1; Lern1; Lrrn6a", "gene_names_refseq": "4930471K13Rik; LERN1; LINGO-1; Lingo1; Lrrn6a; UNQ201", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D1T0", "url": "https://www.uniprot.org/uniprotkb/Q9D1T0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "Q9D1T0", "url": "https://www.uniprot.org/uniprotkb/Q9D1T0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "rs3389034525", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389034525", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "LGLRSNRLKLIPLGVFTGLS", "down_seq": "LTKLDISENKIVILLDYMFQ", "glycosylation": [ { "glytoucan_ac": "G26330YA", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "LIPLGVFTGLSNLTK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn138", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn138", "evidence": [ { "id": "Q9D1T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9D1T0#ptm_processing" } ] } ], "snv": [ { "evidence": [ { "id": "rs3389034525", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389034525" } ], "glycoeffect": [ "n-glyco-sequon-loss" ], "sequence_org": "N", "sequence_mut": "I", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-loss (NLT->ILT).", "chr_id": "9", "chr_pos": "56528175", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "N138", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "138", "end_pos": "138" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "268", "end_pos": "268" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "486", "end_pos": "486" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "536", "end_pos": "536" } ] }, { "type": "snv", "site_list": [ { "start_pos": "138", "end_pos": "138" }, { "start_pos": "538", "end_pos": "538" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "596", "end_pos": "596" } ] } ], "categories": [ "glycosylation_flag", "snv_flag" ], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D1T0-1.196.196", "start_pos": 196, "end_pos": 196, "uniprot_canonical_ac": "Q9D1T0-1", "length": 614, "uniprot_id": "LIGO1_MOUSE", "protein_name": "Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1", "refseq_ac": "NP_001298005", "refseq_name": "leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 isoform 1 precursor", "gene_name": "Lingo1", "gene_names_uniprotkb": "Lingo1; Lern1; Lrrn6a", "gene_names_refseq": "4930471K13Rik; LERN1; LINGO-1; Lingo1; Lrrn6a; UNQ201", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D1T0", "url": "https://www.uniprot.org/uniprotkb/Q9D1T0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] }, { "title": "Capturing site-specific heterogeneity with large-scale N-glycoproteome analysis.", "journal": "Nature communications", "date": "2019", "authors": "Riley NM, Hebert AS, Westphall MS, Coon JJ", "evidence": [ { "database": "GlyConnect", "id": "2465", "url": "https://glyconnect.expasy.org/browser/proteins/2465" } ], "reference": [ { "type": "PubMed", "id": "30899004", "url": "https://glygen.org/publication/PubMed/30899004" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "30899004", "url": "https://glygen.org/publication/PubMed/30899004", "database": "PubMed", "categories": [ "Other" ] }, { "id": "2465", "url": "https://glyconnect.expasy.org/browser/proteins/2465", "database": "GlyConnect", "categories": [ "Glycomics", "Glycoproteomics" ] }, { "id": "Q9D1T0", "url": "https://www.uniprot.org/uniprotkb/Q9D1T0", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "ISHRAFSGLNSLEQLTLEKC", "down_seq": "LTSIPTEALSHLHGLIVLRL", "glycosylation": [ { "glytoucan_ac": "G42581TG", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "CNLTSIPTEALSHLHGLIVLR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn196", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "G70101JE", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn196", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2465", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2465" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn196", "evidence": [ { "id": "Q9D1T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9D1T0#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "138", "end_pos": "138" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "268", "end_pos": "268" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "486", "end_pos": "486" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "536", "end_pos": "536" } ] }, { "type": "snv", "site_list": [ { "start_pos": "138", "end_pos": "138" }, { "start_pos": "538", "end_pos": "538" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "596", "end_pos": "596" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 2 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 2 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 2 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 2 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D1T0-1.258.258", "start_pos": 258, "end_pos": 258, "uniprot_canonical_ac": "Q9D1T0-1", "length": 614, "uniprot_id": "LIGO1_MOUSE", "protein_name": "Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1", "refseq_ac": "NP_001298005", "refseq_name": "leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 isoform 1 precursor", "gene_name": "Lingo1", "gene_names_uniprotkb": "Lingo1; Lern1; Lrrn6a", "gene_names_refseq": "4930471K13Rik; LERN1; LINGO-1; Lingo1; Lrrn6a; UNQ201", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D1T0", "url": "https://www.uniprot.org/uniprotkb/Q9D1T0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "Q9D1T0", "url": "https://www.uniprot.org/uniprotkb/Q9D1T0", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "LEISHWPYLDTMTPNCLYGL", "down_seq": "LTSLSITHCNLTAVPYLAVR", "glycosylation": [ { "glytoucan_ac": "G38253LC", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "VLEISHWPYLDTMTPNCLYGLNLTSLSITHCNLTAVPYLAVR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn258", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn258", "evidence": [ { "id": "Q9D1T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9D1T0#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "138", "end_pos": "138" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "268", "end_pos": "268" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "486", "end_pos": "486" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "536", "end_pos": "536" } ] }, { "type": "snv", "site_list": [ { "start_pos": "138", "end_pos": "138" }, { "start_pos": "538", "end_pos": "538" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "596", "end_pos": "596" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "upstream", "id": "Q9D1T0-1.268.268", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D1T0-1.268.268", "start_pos": 268, "end_pos": 268, "uniprot_canonical_ac": "Q9D1T0-1", "length": 614, "uniprot_id": "LIGO1_MOUSE", "protein_name": "Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1", "refseq_ac": "NP_001298005", "refseq_name": "leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 isoform 1 precursor", "gene_name": "Lingo1", "gene_names_uniprotkb": "Lingo1; Lern1; Lrrn6a", "gene_names_refseq": "4930471K13Rik; LERN1; LINGO-1; Lingo1; Lrrn6a; UNQ201", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D1T0", "url": "https://www.uniprot.org/uniprotkb/Q9D1T0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9D1T0", "url": "https://www.uniprot.org/uniprotkb/Q9D1T0", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "TMTPNCLYGLNLTSLSITHC", "down_seq": "LTAVPYLAVRHLVYLRFLNL", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn268", "evidence": [ { "id": "Q9D1T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9D1T0#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "138", "end_pos": "138" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "268", "end_pos": "268" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "486", "end_pos": "486" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "536", "end_pos": "536" } ] }, { "type": "snv", "site_list": [ { "start_pos": "138", "end_pos": "138" }, { "start_pos": "538", "end_pos": "538" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "596", "end_pos": "596" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "Q9D1T0-1.258.258", "categories": [ "glycosylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q9D1T0-1.287.287", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9D1T0-1.287.287", "start_pos": 287, "end_pos": 287, "uniprot_canonical_ac": "Q9D1T0-1", "length": 614, "uniprot_id": "LIGO1_MOUSE", "protein_name": "Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1", "refseq_ac": "NP_001298005", "refseq_name": "leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 isoform 1 precursor", "gene_name": "Lingo1", "gene_names_uniprotkb": "Lingo1; Lern1; Lrrn6a", "gene_names_refseq": "4930471K13Rik; LERN1; LINGO-1; Lingo1; Lrrn6a; UNQ201", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D1T0", "url": "https://www.uniprot.org/uniprotkb/Q9D1T0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Capturing site-specific heterogeneity with large-scale N-glycoproteome analysis.", "journal": "Nature communications", "date": "2019", "authors": "Riley NM, Hebert AS, Westphall MS, Coon JJ", "evidence": [ { "database": "GlyConnect", "id": "2465", "url": "https://glyconnect.expasy.org/browser/proteins/2465" } ], "reference": [ { "type": "PubMed", "id": "30899004", "url": "https://glygen.org/publication/PubMed/30899004" } ] }, { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "30899004", "url": "https://glygen.org/publication/PubMed/30899004", "database": "PubMed", "categories": [ "Other" ] }, { "id": "2465", "url": "https://glyconnect.expasy.org/browser/proteins/2465", "database": "GlyConnect", "categories": [ "Glycomics", "Glycoproteomics" ] }, { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "Q9D1T0", "url": "https://www.uniprot.org/uniprotkb/Q9D1T0", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "CNLTAVPYLAVRHLVYLRFL", "down_seq": "LSYNPIGTIEGSMLHELLRL", "glycosylation": [ { "glytoucan_ac": "G70101JE", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn287", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2465", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2465" } ] }, { "glytoucan_ac": "G72065MN", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "FLNLSYNPIGTIEGSMLHELLR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn287", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn287", "evidence": [ { "id": "Q9D1T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9D1T0#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "138", "end_pos": "138" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "268", "end_pos": "268" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "486", "end_pos": "486" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "536", "end_pos": "536" } ] }, { "type": "snv", "site_list": [ { "start_pos": "138", "end_pos": "138" }, { "start_pos": "538", "end_pos": "538" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "596", "end_pos": "596" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "Q9D1T0-1.268.268", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 2 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 2 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 2 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 2 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D1T0-1.335.335", "start_pos": 335, "end_pos": 335, "uniprot_canonical_ac": "Q9D1T0-1", "length": 614, "uniprot_id": "LIGO1_MOUSE", "protein_name": "Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1", "refseq_ac": "NP_001298005", "refseq_name": "leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 isoform 1 precursor", "gene_name": "Lingo1", "gene_names_uniprotkb": "Lingo1; Lern1; Lrrn6a", "gene_names_refseq": "4930471K13Rik; LERN1; LINGO-1; Lingo1; Lrrn6a; UNQ201", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D1T0", "url": "https://www.uniprot.org/uniprotkb/Q9D1T0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "Q9D1T0", "url": "https://www.uniprot.org/uniprotkb/Q9D1T0", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "GQLAVVEPYAFRGLNYLRVL", "down_seq": "VSGNQLTTLEESAFHSVGNL", "glycosylation": [ { "glytoucan_ac": "G46071XJ", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "VLNVSGNQLTTLEESAFHSVGNLETLILDSNPLACDCR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn335", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn335", "evidence": [ { "id": "Q9D1T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9D1T0#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "138", "end_pos": "138" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "268", "end_pos": "268" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "486", "end_pos": "486" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "536", "end_pos": "536" } ] }, { "type": "snv", "site_list": [ { "start_pos": "138", "end_pos": "138" }, { "start_pos": "538", "end_pos": "538" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "596", "end_pos": "596" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D1T0-1.486.486", "start_pos": 486, "end_pos": 486, "uniprot_canonical_ac": "Q9D1T0-1", "length": 614, "uniprot_id": "LIGO1_MOUSE", "protein_name": "Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1", "refseq_ac": "NP_001298005", "refseq_name": "leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 isoform 1 precursor", "gene_name": "Lingo1", "gene_names_uniprotkb": "Lingo1; Lern1; Lrrn6a", "gene_names_refseq": "4930471K13Rik; LERN1; LINGO-1; Lingo1; Lrrn6a; UNQ201", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D1T0", "url": "https://www.uniprot.org/uniprotkb/Q9D1T0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "Q9D1T0", "url": "https://www.uniprot.org/uniprotkb/Q9D1T0", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "GRLTVFPDGTLEVRYAQVQD", "down_seq": "GTYLCIAANAGGNDSMPAHL", "glycosylation": [ { "glytoucan_ac": "G79666IR", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "YAQVQDNGTYLCIAANAGGNDSMPAHLHVR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn486", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn486", "evidence": [ { "id": "Q9D1T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9D1T0#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "138", "end_pos": "138" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "268", "end_pos": "268" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "486", "end_pos": "486" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "536", "end_pos": "536" } ] }, { "type": "snv", "site_list": [ { "start_pos": "138", "end_pos": "138" }, { "start_pos": "538", "end_pos": "538" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "596", "end_pos": "596" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D1T0-1.520.520", "start_pos": 520, "end_pos": 520, "uniprot_canonical_ac": "Q9D1T0-1", "length": 614, "uniprot_id": "LIGO1_MOUSE", "protein_name": "Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1", "refseq_ac": "NP_001298005", "refseq_name": "leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 isoform 1 precursor", "gene_name": "Lingo1", "gene_names_uniprotkb": "Lingo1; Lern1; Lrrn6a", "gene_names_refseq": "4930471K13Rik; LERN1; LINGO-1; Lingo1; Lrrn6a; UNQ201", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D1T0", "url": "https://www.uniprot.org/uniprotkb/Q9D1T0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "DSMPAHLHVRSYSPDWPHQP", "down_seq": "KTFAFISNQPGEGEANSTRA", "glycosylation": [ { "glytoucan_ac": "G02815KT", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "SYSPDWPHQPNK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn520", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "138", "end_pos": "138" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "268", "end_pos": "268" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "486", "end_pos": "486" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "536", "end_pos": "536" } ] }, { "type": "snv", "site_list": [ { "start_pos": "138", "end_pos": "138" }, { "start_pos": "538", "end_pos": "538" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "596", "end_pos": "596" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "upstream", "id": "Q9D1T0-1.536.536", "categories": [ "glycosylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q9D1T0-1.538.538", "categories": [ "snv_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D1T0-1.536.536", "start_pos": 536, "end_pos": 536, "uniprot_canonical_ac": "Q9D1T0-1", "length": 614, "uniprot_id": "LIGO1_MOUSE", "protein_name": "Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1", "refseq_ac": "NP_001298005", "refseq_name": "leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 isoform 1 precursor", "gene_name": "Lingo1", "gene_names_uniprotkb": "Lingo1; Lern1; Lrrn6a", "gene_names_refseq": "4930471K13Rik; LERN1; LINGO-1; Lingo1; Lrrn6a; UNQ201", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D1T0", "url": "https://www.uniprot.org/uniprotkb/Q9D1T0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "Q9D1T0", "url": "https://www.uniprot.org/uniprotkb/Q9D1T0", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "PHQPNKTFAFISNQPGEGEA", "down_seq": "STRATVPFPFDIKTLIIATT", "glycosylation": [ { "glytoucan_ac": "G43769HG", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "TFAFISNQPGEGEANSTR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn536", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn536", "evidence": [ { "id": "Q9D1T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9D1T0#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "138", "end_pos": "138" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "268", "end_pos": "268" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "486", "end_pos": "486" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "536", "end_pos": "536" } ] }, { "type": "snv", "site_list": [ { "start_pos": "138", "end_pos": "138" }, { "start_pos": "538", "end_pos": "538" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "596", "end_pos": "596" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "Q9D1T0-1.520.520", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q9D1T0-1.538.538", "categories": [ "snv_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D1T0-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "Q9D1T0-1", "length": 614, "uniprot_id": "LIGO1_MOUSE", "protein_name": "Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1", "refseq_ac": "NP_001298005", "refseq_name": "leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 isoform 1 precursor", "gene_name": "Lingo1", "gene_names_uniprotkb": "Lingo1; Lern1; Lrrn6a", "gene_names_refseq": "4930471K13Rik; LERN1; LINGO-1; Lingo1; Lrrn6a; UNQ201", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D1T0", "url": "https://www.uniprot.org/uniprotkb/Q9D1T0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9D1T0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9D1T0" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] } ], "crossref": [ { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9D1T0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9D1T0", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" }, { "id": "Q9D1T0", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9D1T0" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "138", "end_pos": "138" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "268", "end_pos": "268" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "486", "end_pos": "486" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "536", "end_pos": "536" } ] }, { "type": "snv", "site_list": [ { "start_pos": "138", "end_pos": "138" }, { "start_pos": "538", "end_pos": "538" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "596", "end_pos": "596" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D1T0-1.538.538", "start_pos": 538, "end_pos": 538, "uniprot_canonical_ac": "Q9D1T0-1", "length": 614, "uniprot_id": "LIGO1_MOUSE", "protein_name": "Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1", "refseq_ac": "NP_001298005", "refseq_name": "leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 isoform 1 precursor", "gene_name": "Lingo1", "gene_names_uniprotkb": "Lingo1; Lern1; Lrrn6a", "gene_names_refseq": "4930471K13Rik; LERN1; LINGO-1; Lingo1; Lrrn6a; UNQ201", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D1T0", "url": "https://www.uniprot.org/uniprotkb/Q9D1T0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3389044736", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389044736", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "QPNKTFAFISNQPGEGEANS", "down_seq": "RATVPFPFDIKTLIIATTMG", "snv": [ { "evidence": [ { "id": "rs3389044736", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389044736" } ], "glycoeffect": [ "n-glyco-sequon-loss", "o-glyco-site-loss" ], "sequence_org": "T", "sequence_mut": "I", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-loss (NST->NSI).", "chr_id": "9", "chr_pos": "56526975", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "T538", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "138", "end_pos": "138" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "268", "end_pos": "268" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "486", "end_pos": "486" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "536", "end_pos": "536" } ] }, { "type": "snv", "site_list": [ { "start_pos": "138", "end_pos": "138" }, { "start_pos": "538", "end_pos": "538" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "596", "end_pos": "596" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "Q9D1T0-1.520.520", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q9D1T0-1.536.536", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9D1T0-1.596.596", "start_pos": 596, "end_pos": 596, "uniprot_canonical_ac": "Q9D1T0-1", "length": 614, "uniprot_id": "LIGO1_MOUSE", "protein_name": "Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1", "refseq_ac": "NP_001298005", "refseq_name": "leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 isoform 1 precursor", "gene_name": "Lingo1", "gene_names_uniprotkb": "Lingo1; Lern1; Lrrn6a", "gene_names_refseq": "4930471K13Rik; LERN1; LINGO-1; Lingo1; Lrrn6a; UNQ201", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D1T0", "url": "https://www.uniprot.org/uniprotkb/Q9D1T0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9D1T0", "url": "https://www.uniprot.org/uniprotkb/Q9D1T0" }, { "database": "iPTMnet", "id": "Q9D1T0", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9D1T0" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "title": "Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.", "journal": "Molecular & cellular proteomics : MCP", "date": "2007", "authors": "Munton RP, Tweedie-Cullen R, Livingstone-Zatchej M, Weinandy F, Waidelich M, Longo D, Gehrig P, Potthast F, Rutishauser D, Gerrits B, Panse C, Schlapbach R, Mansuy IM", "evidence": [ { "database": "iPTMnet", "id": "Q9D1T0", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9D1T0" } ], "reference": [ { "type": "PubMed", "id": "17114649", "url": "https://glygen.org/publication/PubMed/17114649" } ] } ], "crossref": [ { "id": "Q9D1T0", "url": "https://www.uniprot.org/uniprotkb/Q9D1T0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9D1T0", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=Q9D1T0", "database": "PRO", "categories": [ "Other" ] }, { "id": "Q9D1T0", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9D1T0", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "17114649", "url": "https://glygen.org/publication/PubMed/17114649", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "WSRGKGNTKHNIEIEYVPRK", "down_seq": "DAGISSADAPRKFNMKMI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9D1T0", "url": "https://www.uniprot.org/uniprotkb/Q9D1T0" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "PRO", "id": "Q9D1T0", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=Q9D1T0" }, { "database": "iPTMnet", "id": "Q9D1T0", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9D1T0" }, { "database": "PubMed", "id": "17114649", "url": "https://glygen.org/publication/PubMed/17114649" } ], "site_lbl": "Ser596" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "138", "end_pos": "138" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "268", "end_pos": "268" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "486", "end_pos": "486" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "536", "end_pos": "536" } ] }, { "type": "snv", "site_list": [ { "start_pos": "138", "end_pos": "138" }, { "start_pos": "538", "end_pos": "538" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "596", "end_pos": "596" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8K2F8-1.371.371", "start_pos": 371, "end_pos": 371, "uniprot_canonical_ac": "Q8K2F8-1", "length": 462, "uniprot_id": "LS14A_MOUSE", "protein_name": "Protein LSM14 homolog A", "refseq_ac": "NP_080224", "refseq_name": "protein LSM14 homolog A isoform 1", "gene_name": "Lsm14a", "gene_names_uniprotkb": "Lsm14a; Fam61a; Rap55a", "gene_names_refseq": "2700023B17Rik; Lsm14a; Tral; mRAP55A", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8K2F8", "url": "https://www.uniprot.org/uniprotkb/Q8K2F8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "DEEDPLGPNCYYDKTKSFFD", "down_seq": "ISCDDNRERRPTWAEERRLN", "glycosylation": [ { "glytoucan_ac": "G62765YT", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "TKSFFDNISCDDNRER", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn371", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "371", "end_pos": "371" }, { "start_pos": "86", "end_pos": "86" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "227", "end_pos": "227" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8K2F8-1.86.86", "start_pos": 86, "end_pos": 86, "uniprot_canonical_ac": "Q8K2F8-1", "length": 462, "uniprot_id": "LS14A_MOUSE", "protein_name": "Protein LSM14 homolog A", "refseq_ac": "NP_080224", "refseq_name": "protein LSM14 homolog A isoform 1", "gene_name": "Lsm14a", "gene_names_uniprotkb": "Lsm14a; Fam61a; Rap55a", "gene_names_refseq": "2700023B17Rik; Lsm14a; Tral; mRAP55A", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8K2F8", "url": "https://www.uniprot.org/uniprotkb/Q8K2F8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8K2F8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8K2F8" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Dynamic eIF3a O-GlcNAcylation controls translation reinitiation during nutrient stress.", "journal": "Nature chemical biology", "date": "2022", "authors": "Shu XE, Mao Y, Jia L, Qian SB", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8K2F8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8K2F8" } ], "reference": [ { "type": "PubMed", "id": "34887587", "url": "https://glygen.org/publication/PubMed/34887587" } ] } ], "crossref": [ { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8K2F8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8K2F8", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "34887587", "url": "https://glygen.org/publication/PubMed/34887587", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "IFRGSDIKDLTVCEPPKPQC", "down_seq": "LPQDPAIVQSSLGSSSSSFQ", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser86", "evidence": [ { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "Q8K2F8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8K2F8" }, { "id": "34887587", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34887587" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "371", "end_pos": "371" }, { "start_pos": "86", "end_pos": "86" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "227", "end_pos": "227" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8K2F8-1.182.182", "start_pos": 182, "end_pos": 182, "uniprot_canonical_ac": "Q8K2F8-1", "length": 462, "uniprot_id": "LS14A_MOUSE", "protein_name": "Protein LSM14 homolog A", "refseq_ac": "NP_080224", "refseq_name": "protein LSM14 homolog A isoform 1", "gene_name": "Lsm14a", "gene_names_uniprotkb": "Lsm14a; Fam61a; Rap55a", "gene_names_refseq": "2700023B17Rik; Lsm14a; Tral; mRAP55A", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8K2F8", "url": "https://www.uniprot.org/uniprotkb/Q8K2F8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8K2F8", "url": "https://www.uniprot.org/uniprotkb/Q8K2F8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VGSAFTQDTRSVKPQLAQGR", "down_seq": "SPQLDPLRKSPTMEQAVQTA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8K2F8", "url": "https://www.uniprot.org/uniprotkb/Q8K2F8" } ], "site_lbl": "Ser182" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "371", "end_pos": "371" }, { "start_pos": "86", "end_pos": "86" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "227", "end_pos": "227" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "Q8K2F8-1.183.183", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q8K2F8-1.192.192", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "Q8K2F8-1.194.194", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8K2F8-1.183.183", "start_pos": 183, "end_pos": 183, "uniprot_canonical_ac": "Q8K2F8-1", "length": 462, "uniprot_id": "LS14A_MOUSE", "protein_name": "Protein LSM14 homolog A", "refseq_ac": "NP_080224", "refseq_name": "protein LSM14 homolog A isoform 1", "gene_name": "Lsm14a", "gene_names_uniprotkb": "Lsm14a; Fam61a; Rap55a", "gene_names_refseq": "2700023B17Rik; Lsm14a; Tral; mRAP55A", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8K2F8", "url": "https://www.uniprot.org/uniprotkb/Q8K2F8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8K2F8", "url": "https://www.uniprot.org/uniprotkb/Q8K2F8" }, { "database": "iPTMnet", "id": "Q8K2F8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8K2F8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q8K2F8", "url": "https://www.uniprot.org/uniprotkb/Q8K2F8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8K2F8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8K2F8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GSAFTQDTRSVKPQLAQGRS", "down_seq": "PQLDPLRKSPTMEQAVQTAS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8K2F8", "url": "https://www.uniprot.org/uniprotkb/Q8K2F8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q8K2F8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8K2F8" } ], "site_lbl": "Ser183" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "371", "end_pos": "371" }, { "start_pos": "86", "end_pos": "86" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "227", "end_pos": "227" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "Q8K2F8-1.182.182", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q8K2F8-1.192.192", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q8K2F8-1.194.194", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8K2F8-1.192.192", "start_pos": 192, "end_pos": 192, "uniprot_canonical_ac": "Q8K2F8-1", "length": 462, "uniprot_id": "LS14A_MOUSE", "protein_name": "Protein LSM14 homolog A", "refseq_ac": "NP_080224", "refseq_name": "protein LSM14 homolog A isoform 1", "gene_name": "Lsm14a", "gene_names_uniprotkb": "Lsm14a; Fam61a; Rap55a", "gene_names_refseq": "2700023B17Rik; Lsm14a; Tral; mRAP55A", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8K2F8", "url": "https://www.uniprot.org/uniprotkb/Q8K2F8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8K2F8", "url": "https://www.uniprot.org/uniprotkb/Q8K2F8" }, { "database": "iPTMnet", "id": "Q8K2F8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8K2F8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q8K2F8", "url": "https://www.uniprot.org/uniprotkb/Q8K2F8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8K2F8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8K2F8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SVKPQLAQGRSSPQLDPLRK", "down_seq": "PTMEQAVQTASAHLPAPAPV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8K2F8", "url": "https://www.uniprot.org/uniprotkb/Q8K2F8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q8K2F8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8K2F8" } ], "site_lbl": "Ser192" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "371", "end_pos": "371" }, { "start_pos": "86", "end_pos": "86" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "227", "end_pos": "227" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "Q8K2F8-1.182.182", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "Q8K2F8-1.183.183", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q8K2F8-1.194.194", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8K2F8-1.194.194", "start_pos": 194, "end_pos": 194, "uniprot_canonical_ac": "Q8K2F8-1", "length": 462, "uniprot_id": "LS14A_MOUSE", "protein_name": "Protein LSM14 homolog A", "refseq_ac": "NP_080224", "refseq_name": "protein LSM14 homolog A isoform 1", "gene_name": "Lsm14a", "gene_names_uniprotkb": "Lsm14a; Fam61a; Rap55a", "gene_names_refseq": "2700023B17Rik; Lsm14a; Tral; mRAP55A", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8K2F8", "url": "https://www.uniprot.org/uniprotkb/Q8K2F8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8K2F8", "url": "https://www.uniprot.org/uniprotkb/Q8K2F8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "KPQLAQGRSSPQLDPLRKSP", "down_seq": "MEQAVQTASAHLPAPAPVGR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q8K2F8", "url": "https://www.uniprot.org/uniprotkb/Q8K2F8" } ], "site_lbl": "Thr194" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "371", "end_pos": "371" }, { "start_pos": "86", "end_pos": "86" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "227", "end_pos": "227" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "Q8K2F8-1.182.182", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "Q8K2F8-1.183.183", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q8K2F8-1.192.192", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8K2F8-1.216.216", "start_pos": 216, "end_pos": 216, "uniprot_canonical_ac": "Q8K2F8-1", "length": 462, "uniprot_id": "LS14A_MOUSE", "protein_name": "Protein LSM14 homolog A", "refseq_ac": "NP_080224", "refseq_name": "protein LSM14 homolog A isoform 1", "gene_name": "Lsm14a", "gene_names_uniprotkb": "Lsm14a; Fam61a; Rap55a", "gene_names_refseq": "2700023B17Rik; Lsm14a; Tral; mRAP55A", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8K2F8", "url": "https://www.uniprot.org/uniprotkb/Q8K2F8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.", "journal": "Molecular & cellular proteomics : MCP", "date": "2009", "authors": "Sweet SM, Bailey CM, Cunningham DL, Heath JK, Cooper HJ", "evidence": [ { "database": "UniProtKB", "id": "Q8K2F8", "url": "https://www.uniprot.org/uniprotkb/Q8K2F8" }, { "database": "iPTMnet", "id": "Q8K2F8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8K2F8" } ], "reference": [ { "type": "PubMed", "id": "19131326", "url": "https://glygen.org/publication/PubMed/19131326" } ] } ], "crossref": [ { "id": "Q8K2F8", "url": "https://www.uniprot.org/uniprotkb/Q8K2F8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19131326", "url": "https://glygen.org/publication/PubMed/19131326", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8K2F8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8K2F8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EQAVQTASAHLPAPAPVGRR", "down_seq": "PVPARPLPPTSQKAIDNQEH", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8K2F8", "url": "https://www.uniprot.org/uniprotkb/Q8K2F8" }, { "database": "PubMed", "id": "19131326", "url": "https://glygen.org/publication/PubMed/19131326" }, { "database": "iPTMnet", "id": "Q8K2F8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8K2F8" } ], "site_lbl": "Ser216" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "371", "end_pos": "371" }, { "start_pos": "86", "end_pos": "86" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "227", "end_pos": "227" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "upstream", "id": "Q8K2F8-1.227.227", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8K2F8-1.227.227", "start_pos": 227, "end_pos": 227, "uniprot_canonical_ac": "Q8K2F8-1", "length": 462, "uniprot_id": "LS14A_MOUSE", "protein_name": "Protein LSM14 homolog A", "refseq_ac": "NP_080224", "refseq_name": "protein LSM14 homolog A isoform 1", "gene_name": "Lsm14a", "gene_names_uniprotkb": "Lsm14a; Fam61a; Rap55a", "gene_names_refseq": "2700023B17Rik; Lsm14a; Tral; mRAP55A", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8K2F8", "url": "https://www.uniprot.org/uniprotkb/Q8K2F8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8K2F8", "url": "https://www.uniprot.org/uniprotkb/Q8K2F8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PAPAPVGRRSPVPARPLPPT", "down_seq": "QKAIDNQEHRRAEVHKVPRP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8K2F8", "url": "https://www.uniprot.org/uniprotkb/Q8K2F8" } ], "site_lbl": "Ser227" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "371", "end_pos": "371" }, { "start_pos": "86", "end_pos": "86" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "182", "end_pos": "182" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "227", "end_pos": "227" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "Q8K2F8-1.216.216", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P97311-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "P97311-1", "length": 821, "uniprot_id": "MCM6_MOUSE", "protein_name": "DNA replication licensing factor MCM6", "refseq_ac": "NP_032593", "refseq_name": "DNA replication licensing factor MCM6 isoform 1", "gene_name": "Mcm6", "gene_names_uniprotkb": "Mcm6; Mcmd6; Mis5", "gene_names_refseq": "ASP-l1; D1Wsu22e; Mcm6; Mcmd6", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P97311", "url": "https://www.uniprot.org/uniprotkb/P97311" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Dynamic O-GlcNAcylation governs long-range chromatin interactions in V(D)J recombination during early B-cell development.", "journal": "Cellular & molecular immunology", "date": "2025-01", "authors": "Jeon Bong Chan, Kim Yu-Ji, Park Ae Kyung, Song Mi-Ran, Na Ki Myeong, Lee Juwon, An Dasom, Park Yeseul, Hwang Heeyoun, Kim Tae-Don, Lim Junghyun, Park Sung-Kyun", "evidence": [ { "database": "O-GlcNAc Database", "id": "P97311", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P97311" } ], "reference": [ { "type": "PubMed", "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609" } ] } ], "crossref": [ { "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P97311", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P97311", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "39627609", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39627609" }, { "id": "P97311", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P97311" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "402", "end_pos": "403" }, { "start_pos": "460", "end_pos": "461" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "13", "end_pos": "13" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "689", "end_pos": "689" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "791", "end_pos": "791" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "upstream", "id": "P97311-1.13.13", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P97311-1.402.403", "start_pos": 402, "end_pos": 403, "uniprot_canonical_ac": "P97311-1", "length": 821, "uniprot_id": "MCM6_MOUSE", "protein_name": "DNA replication licensing factor MCM6", "refseq_ac": "NP_032593", "refseq_name": "DNA replication licensing factor MCM6 isoform 1", "gene_name": "Mcm6", "gene_names_uniprotkb": "Mcm6; Mcmd6; Mis5", "gene_names_refseq": "ASP-l1; D1Wsu22e; Mcm6; Mcmd6", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P97311", "url": "https://www.uniprot.org/uniprotkb/P97311" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Biochemical analysis of the intrinsic Mcm4-Mcm6-mcm7 DNA helicase activity.", "journal": "Molecular and cellular biology", "date": "1999", "authors": "You Z, Komamura Y, Ishimi Y", "evidence": [ { "database": "UniProtKB", "id": "P97311", "url": "https://www.uniprot.org/uniprotkb/P97311" } ], "reference": [ { "type": "PubMed", "id": "10567526", "url": "https://glygen.org/publication/PubMed/10567526" } ] } ], "crossref": [ { "id": "P97311", "url": "https://www.uniprot.org/uniprotkb/P97311", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10567526", "url": "https://glygen.org/publication/PubMed/10567526", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "KS", "start_aa": "K", "up_seq": "EGTSLRGDINVCIVGDPSTA", "down_seq": "QFLKHVDEFSPRAVYTSGKA", "mutagenesis": [ { "sequence_org": "KS", "sequence_mut": "AA", "comment": "Decreased MCM complex DNA helicase activity. Loss of ATP-binding. Decreased MCM complex ATPase activity. No effect on MCM complex formation.", "evidence": [ { "database": "UniProtKB", "id": "P97311", "url": "https://www.uniprot.org/uniprotkb/P97311" }, { "database": "PubMed", "id": "10567526", "url": "https://glygen.org/publication/PubMed/10567526" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "402", "end_pos": "403" }, { "start_pos": "460", "end_pos": "461" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "13", "end_pos": "13" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "689", "end_pos": "689" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "791", "end_pos": "791" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P97311-1.460.461", "start_pos": 460, "end_pos": 461, "uniprot_canonical_ac": "P97311-1", "length": 821, "uniprot_id": "MCM6_MOUSE", "protein_name": "DNA replication licensing factor MCM6", "refseq_ac": "NP_032593", "refseq_name": "DNA replication licensing factor MCM6 isoform 1", "gene_name": "Mcm6", "gene_names_uniprotkb": "Mcm6; Mcmd6; Mis5", "gene_names_refseq": "ASP-l1; D1Wsu22e; Mcm6; Mcmd6", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P97311", "url": "https://www.uniprot.org/uniprotkb/P97311" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Biochemical analysis of the intrinsic Mcm4-Mcm6-mcm7 DNA helicase activity.", "journal": "Molecular and cellular biology", "date": "1999", "authors": "You Z, Komamura Y, Ishimi Y", "evidence": [ { "database": "UniProtKB", "id": "P97311", "url": "https://www.uniprot.org/uniprotkb/P97311" } ], "reference": [ { "type": "PubMed", "id": "10567526", "url": "https://glygen.org/publication/PubMed/10567526" } ] } ], "crossref": [ { "id": "P97311", "url": "https://www.uniprot.org/uniprotkb/P97311", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10567526", "url": "https://glygen.org/publication/PubMed/10567526", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "DE", "start_aa": "D", "up_seq": "HEFVIEAGALMLADNGVCCI", "down_seq": "FDKMDMRDQVAIHEAMEQQT", "mutagenesis": [ { "sequence_org": "DE", "sequence_mut": "AA", "comment": "Loss of MCM complex DNA helicase activity. Loss of ATP-binding. No effect on MCM complex formation. No effect on MCM complex ATPase activity and ssDNA binding.", "evidence": [ { "database": "UniProtKB", "id": "P97311", "url": "https://www.uniprot.org/uniprotkb/P97311" }, { "database": "PubMed", "id": "10567526", "url": "https://glygen.org/publication/PubMed/10567526" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "402", "end_pos": "403" }, { "start_pos": "460", "end_pos": "461" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "13", "end_pos": "13" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "689", "end_pos": "689" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "791", "end_pos": "791" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P97311-1.13.13", "start_pos": 13, "end_pos": 13, "uniprot_canonical_ac": "P97311-1", "length": 821, "uniprot_id": "MCM6_MOUSE", "protein_name": "DNA replication licensing factor MCM6", "refseq_ac": "NP_032593", "refseq_name": "DNA replication licensing factor MCM6 isoform 1", "gene_name": "Mcm6", "gene_names_uniprotkb": "Mcm6; Mcmd6; Mis5", "gene_names_refseq": "ASP-l1; D1Wsu22e; Mcm6; Mcmd6", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P97311", "url": "https://www.uniprot.org/uniprotkb/P97311" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P97311", "url": "https://www.uniprot.org/uniprotkb/P97311", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MDLAAAAEPGAG", "down_seq": "QHPEVRDEVAEKCQKLFLDF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P97311", "url": "https://www.uniprot.org/uniprotkb/P97311" } ], "site_lbl": "Ser13" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "402", "end_pos": "403" }, { "start_pos": "460", "end_pos": "461" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "13", "end_pos": "13" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "689", "end_pos": "689" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "791", "end_pos": "791" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P97311-1.0.0", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P97311-1.219.219", "start_pos": 219, "end_pos": 219, "uniprot_canonical_ac": "P97311-1", "length": 821, "uniprot_id": "MCM6_MOUSE", "protein_name": "DNA replication licensing factor MCM6", "refseq_ac": "NP_032593", "refseq_name": "DNA replication licensing factor MCM6 isoform 1", "gene_name": "Mcm6", "gene_names_uniprotkb": "Mcm6; Mcmd6; Mis5", "gene_names_refseq": "ASP-l1; D1Wsu22e; Mcm6; Mcmd6", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P97311", "url": "https://www.uniprot.org/uniprotkb/P97311" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P97311", "url": "https://www.uniprot.org/uniprotkb/P97311", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RFVDFQKVRIQETQAELPRG", "down_seq": "IPRSLEVILRAEAVESAQAG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P97311", "url": "https://www.uniprot.org/uniprotkb/P97311" } ], "site_lbl": "Ser219" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "402", "end_pos": "403" }, { "start_pos": "460", "end_pos": "461" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "13", "end_pos": "13" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "689", "end_pos": "689" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "791", "end_pos": "791" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P97311-1.271.271", "start_pos": 271, "end_pos": 271, "uniprot_canonical_ac": "P97311-1", "length": 821, "uniprot_id": "MCM6_MOUSE", "protein_name": "DNA replication licensing factor MCM6", "refseq_ac": "NP_032593", "refseq_name": "DNA replication licensing factor MCM6 isoform 1", "gene_name": "Mcm6", "gene_names_uniprotkb": "Mcm6; Mcmd6; Mis5", "gene_names_refseq": "ASP-l1; D1Wsu22e; Mcm6; Mcmd6", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P97311", "url": "https://www.uniprot.org/uniprotkb/P97311" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P97311", "url": "https://www.uniprot.org/uniprotkb/P97311" }, { "database": "iPTMnet", "id": "P97311", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P97311" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "P97311", "url": "https://www.uniprot.org/uniprotkb/P97311", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P97311", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P97311", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VPDVSKLSTPGARAETNSRV", "down_seq": "GADGYETEGIRGLRALGVRD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P97311", "url": "https://www.uniprot.org/uniprotkb/P97311" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "P97311", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P97311" } ], "site_lbl": "Ser271" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "402", "end_pos": "403" }, { "start_pos": "460", "end_pos": "461" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "13", "end_pos": "13" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "689", "end_pos": "689" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "791", "end_pos": "791" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "upstream", "id": "P97311-1.278.278", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P97311-1.278.278", "start_pos": 278, "end_pos": 278, "uniprot_canonical_ac": "P97311-1", "length": 821, "uniprot_id": "MCM6_MOUSE", "protein_name": "DNA replication licensing factor MCM6", "refseq_ac": "NP_032593", "refseq_name": "DNA replication licensing factor MCM6 isoform 1", "gene_name": "Mcm6", "gene_names_uniprotkb": "Mcm6; Mcmd6; Mis5", "gene_names_refseq": "ASP-l1; D1Wsu22e; Mcm6; Mcmd6", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P97311", "url": "https://www.uniprot.org/uniprotkb/P97311" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P97311", "url": "https://www.uniprot.org/uniprotkb/P97311", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "STPGARAETNSRVSGADGYE", "down_seq": "EGIRGLRALGVRDLSYRLVF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P97311", "url": "https://www.uniprot.org/uniprotkb/P97311" } ], "site_lbl": "Thr278" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "402", "end_pos": "403" }, { "start_pos": "460", "end_pos": "461" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "13", "end_pos": "13" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "689", "end_pos": "689" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "791", "end_pos": "791" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "P97311-1.271.271", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P97311-1.689.689", "start_pos": 689, "end_pos": 689, "uniprot_canonical_ac": "P97311-1", "length": 821, "uniprot_id": "MCM6_MOUSE", "protein_name": "DNA replication licensing factor MCM6", "refseq_ac": "NP_032593", "refseq_name": "DNA replication licensing factor MCM6 isoform 1", "gene_name": "Mcm6", "gene_names_uniprotkb": "Mcm6; Mcmd6; Mis5", "gene_names_refseq": "ASP-l1; D1Wsu22e; Mcm6; Mcmd6", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P97311", "url": "https://www.uniprot.org/uniprotkb/P97311" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P97311", "url": "https://www.uniprot.org/uniprotkb/P97311" }, { "database": "iPTMnet", "id": "P97311", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P97311" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "P97311", "url": "https://www.uniprot.org/uniprotkb/P97311", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P97311", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P97311", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EEEIQMETDEGQGGVNGHAD", "down_seq": "PAPVNRFNGSSEDASQETVS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P97311", "url": "https://www.uniprot.org/uniprotkb/P97311" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "P97311", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P97311" } ], "site_lbl": "Ser689" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "402", "end_pos": "403" }, { "start_pos": "460", "end_pos": "461" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "13", "end_pos": "13" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "689", "end_pos": "689" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "791", "end_pos": "791" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "upstream", "id": "P97311-1.704.704", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P97311-1.704.704", "start_pos": 704, "end_pos": 704, "uniprot_canonical_ac": "P97311-1", "length": 821, "uniprot_id": "MCM6_MOUSE", "protein_name": "DNA replication licensing factor MCM6", "refseq_ac": "NP_032593", "refseq_name": "DNA replication licensing factor MCM6 isoform 1", "gene_name": "Mcm6", "gene_names_uniprotkb": "Mcm6; Mcmd6; Mis5", "gene_names_refseq": "ASP-l1; D1Wsu22e; Mcm6; Mcmd6", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P97311", "url": "https://www.uniprot.org/uniprotkb/P97311" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P97311", "url": "https://www.uniprot.org/uniprotkb/P97311" }, { "database": "iPTMnet", "id": "P97311", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P97311" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "P97311", "url": "https://www.uniprot.org/uniprotkb/P97311", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P97311", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P97311", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NGHADSPAPVNRFNGSSEDA", "down_seq": "QETVSKPSLRLGFAEYCRIS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P97311", "url": "https://www.uniprot.org/uniprotkb/P97311" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "P97311", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P97311" } ], "site_lbl": "Ser704" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "402", "end_pos": "403" }, { "start_pos": "460", "end_pos": "461" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "13", "end_pos": "13" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "689", "end_pos": "689" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "791", "end_pos": "791" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P97311-1.689.689", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P97311-1.762.762", "start_pos": 762, "end_pos": 762, "uniprot_canonical_ac": "P97311-1", "length": 821, "uniprot_id": "MCM6_MOUSE", "protein_name": "DNA replication licensing factor MCM6", "refseq_ac": "NP_032593", "refseq_name": "DNA replication licensing factor MCM6 isoform 1", "gene_name": "Mcm6", "gene_names_uniprotkb": "Mcm6; Mcmd6; Mis5", "gene_names_refseq": "ASP-l1; D1Wsu22e; Mcm6; Mcmd6", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P97311", "url": "https://www.uniprot.org/uniprotkb/P97311" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P97311", "url": "https://www.uniprot.org/uniprotkb/P97311" }, { "database": "iPTMnet", "id": "P97311", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P97311" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "P97311", "url": "https://www.uniprot.org/uniprotkb/P97311", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P97311", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P97311", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ALKRSELVNWYLKEIESEID", "down_seq": "EEELINKKTIIEKVVHRLTH", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P97311", "url": "https://www.uniprot.org/uniprotkb/P97311" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "P97311", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P97311" } ], "site_lbl": "Ser762" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "402", "end_pos": "403" }, { "start_pos": "460", "end_pos": "461" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "13", "end_pos": "13" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "689", "end_pos": "689" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "791", "end_pos": "791" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P97311-1.791.791", "start_pos": 791, "end_pos": 791, "uniprot_canonical_ac": "P97311-1", "length": 821, "uniprot_id": "MCM6_MOUSE", "protein_name": "DNA replication licensing factor MCM6", "refseq_ac": "NP_032593", "refseq_name": "DNA replication licensing factor MCM6 isoform 1", "gene_name": "Mcm6", "gene_names_uniprotkb": "Mcm6; Mcmd6; Mis5", "gene_names_refseq": "ASP-l1; D1Wsu22e; Mcm6; Mcmd6", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P97311", "url": "https://www.uniprot.org/uniprotkb/P97311" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.", "journal": "Science (New York, N.Y.)", "date": "2007", "authors": "Matsuoka S, Ballif BA, Smogorzewska A, McDonald ER 3rd, Hurov KE, Luo J, Bakalarski CE, Zhao Z, Solimini N, Lerenthal Y, Shiloh Y, Gygi SP, Elledge SJ", "evidence": [ { "database": "UniProtKB", "id": "P97311", "url": "https://www.uniprot.org/uniprotkb/P97311" }, { "database": "iPTMnet", "id": "P97311", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P97311" } ], "reference": [ { "type": "PubMed", "id": "17525332", "url": "https://glygen.org/publication/PubMed/17525332" } ] } ], "crossref": [ { "id": "P97311", "url": "https://www.uniprot.org/uniprotkb/P97311", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17525332", "url": "https://glygen.org/publication/PubMed/17525332", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P97311", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P97311", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "TIIEKVVHRLTHYDHVLIEL", "down_seq": "QAGLKGSSEGSESYEEDPYL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P97311", "url": "https://www.uniprot.org/uniprotkb/P97311" }, { "database": "PubMed", "id": "17525332", "url": "https://glygen.org/publication/PubMed/17525332" }, { "database": "iPTMnet", "id": "P97311", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P97311" } ], "site_lbl": "Thr791" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "402", "end_pos": "403" }, { "start_pos": "460", "end_pos": "461" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "13", "end_pos": "13" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "689", "end_pos": "689" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "762", "end_pos": "762" }, { "start_pos": "791", "end_pos": "791" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q5DU41-1.594.594", "start_pos": 594, "end_pos": 594, "uniprot_canonical_ac": "Q5DU41-1", "length": 803, "uniprot_id": "LRC8B_MOUSE", "protein_name": "Volume-regulated anion channel subunit LRRC8B", "refseq_ac": "NP_001028722", "refseq_name": "volume-regulated anion channel subunit LRRC8B", "gene_name": "Lrrc8b", "gene_names_uniprotkb": "Lrrc8b; Kiaa0231", "gene_names_refseq": "2210408K08Rik; Lrrc8b; Ta-lrrp; mKIAA0231", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q5DU41", "url": "https://www.uniprot.org/uniprotkb/Q5DU41" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation Is Essential for Rapid Pomc Expression and Cell Proliferation in Corticotropic Tumor Cells.", "journal": "Endocrinology", "date": "2021", "authors": "Massman LJ, Pereckas M, Zwagerman NT, Olivier-Van Stichelen S", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q5DU41", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q5DU41" } ], "reference": [ { "type": "PubMed", "id": "34418053", "url": "https://glygen.org/publication/PubMed/34418053" } ] }, { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q5DU41", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q5DU41" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] } ], "crossref": [ { "id": "34418053", "url": "https://glygen.org/publication/PubMed/34418053", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q5DU41", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q5DU41", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KLVVLNNLKKMVNLKSLELL", "down_seq": "CDLERIPHSIFSLNNLHELD", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser594", "evidence": [ { "id": "34418053", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34418053" }, { "id": "Q5DU41", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q5DU41" }, { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "594", "end_pos": "594" }, { "start_pos": "78", "end_pos": "78" } ] }, { "type": "snv", "site_list": [ { "start_pos": "634", "end_pos": "634" }, { "start_pos": "646", "end_pos": "646" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "186", "end_pos": "186" }, { "start_pos": "196", "end_pos": "196" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q5DU41-1.78.78", "start_pos": 78, "end_pos": 78, "uniprot_canonical_ac": "Q5DU41-1", "length": 803, "uniprot_id": "LRC8B_MOUSE", "protein_name": "Volume-regulated anion channel subunit LRRC8B", "refseq_ac": "NP_001028722", "refseq_name": "volume-regulated anion channel subunit LRRC8B", "gene_name": "Lrrc8b", "gene_names_uniprotkb": "Lrrc8b; Kiaa0231", "gene_names_refseq": "2210408K08Rik; Lrrc8b; Ta-lrrp; mKIAA0231", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q5DU41", "url": "https://www.uniprot.org/uniprotkb/Q5DU41" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "Q5DU41", "url": "https://www.uniprot.org/uniprotkb/Q5DU41", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "CKVEFDNQCAVPWDLLKGSE", "down_seq": "ASSNSGLLLPLPLRIQNDLH", "glycosylation": [ { "glytoucan_ac": "G83460ZZ", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "GSENASSNSGLLLPLPLR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn78", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn78", "evidence": [ { "id": "Q5DU41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5DU41#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "594", "end_pos": "594" }, { "start_pos": "78", "end_pos": "78" } ] }, { "type": "snv", "site_list": [ { "start_pos": "634", "end_pos": "634" }, { "start_pos": "646", "end_pos": "646" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "186", "end_pos": "186" }, { "start_pos": "196", "end_pos": "196" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q5DU41-1.634.634", "start_pos": 634, "end_pos": 634, "uniprot_canonical_ac": "Q5DU41-1", "length": 803, "uniprot_id": "LRC8B_MOUSE", "protein_name": "Volume-regulated anion channel subunit LRRC8B", "refseq_ac": "NP_001028722", "refseq_name": "volume-regulated anion channel subunit LRRC8B", "gene_name": "Lrrc8b", "gene_names_uniprotkb": "Lrrc8b; Kiaa0231", "gene_names_refseq": "2210408K08Rik; Lrrc8b; Ta-lrrp; mKIAA0231", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q5DU41", "url": "https://www.uniprot.org/uniprotkb/Q5DU41" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388773992", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388773992", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DLKENNLKTVEEIISFQHLP", "down_seq": "LSCLKLWHNNIAYIPAQIGA", "snv": [ { "evidence": [ { "id": "rs3388773992", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388773992" } ], "glycoeffect": [ "n-glyco-sequon-gain", "o-glyco-site-loss" ], "sequence_org": "S", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (SLS->NLS).", "chr_id": "5", "chr_pos": "105629556", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S634", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "594", "end_pos": "594" }, { "start_pos": "78", "end_pos": "78" } ] }, { "type": "snv", "site_list": [ { "start_pos": "634", "end_pos": "634" }, { "start_pos": "646", "end_pos": "646" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "186", "end_pos": "186" }, { "start_pos": "196", "end_pos": "196" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "upstream", "id": "Q5DU41-1.646.646", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q5DU41-1.646.646", "start_pos": 646, "end_pos": 646, "uniprot_canonical_ac": "Q5DU41-1", "length": 803, "uniprot_id": "LRC8B_MOUSE", "protein_name": "Volume-regulated anion channel subunit LRRC8B", "refseq_ac": "NP_001028722", "refseq_name": "volume-regulated anion channel subunit LRRC8B", "gene_name": "Lrrc8b", "gene_names_uniprotkb": "Lrrc8b; Kiaa0231", "gene_names_refseq": "2210408K08Rik; Lrrc8b; Ta-lrrp; mKIAA0231", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q5DU41", "url": "https://www.uniprot.org/uniprotkb/Q5DU41" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388768048", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388768048", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "A", "start_aa": "A", "up_seq": "IISFQHLPSLSCLKLWHNNI", "down_seq": "YIPAQIGALSNLEQLFLGHN", "snv": [ { "evidence": [ { "id": "rs3388768048", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388768048" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "A", "sequence_mut": "T", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (NIA->NIT).", "chr_id": "5", "chr_pos": "105629591", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "A646", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "594", "end_pos": "594" }, { "start_pos": "78", "end_pos": "78" } ] }, { "type": "snv", "site_list": [ { "start_pos": "634", "end_pos": "634" }, { "start_pos": "646", "end_pos": "646" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "186", "end_pos": "186" }, { "start_pos": "196", "end_pos": "196" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "Q5DU41-1.634.634", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q5DU41-1.186.186", "start_pos": 186, "end_pos": 186, "uniprot_canonical_ac": "Q5DU41-1", "length": 803, "uniprot_id": "LRC8B_MOUSE", "protein_name": "Volume-regulated anion channel subunit LRRC8B", "refseq_ac": "NP_001028722", "refseq_name": "volume-regulated anion channel subunit LRRC8B", "gene_name": "Lrrc8b", "gene_names_uniprotkb": "Lrrc8b; Kiaa0231", "gene_names_refseq": "2210408K08Rik; Lrrc8b; Ta-lrrp; mKIAA0231", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q5DU41", "url": "https://www.uniprot.org/uniprotkb/Q5DU41" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q5DU41", "url": "https://www.uniprot.org/uniprotkb/Q5DU41" }, { "database": "iPTMnet", "id": "Q5DU41", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5DU41" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q5DU41", "url": "https://www.uniprot.org/uniprotkb/Q5DU41", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q5DU41", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5DU41", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TRALSETVAEQSVRPLKLSK", "down_seq": "KTLLSTSGGSADIDASKQSL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q5DU41", "url": "https://www.uniprot.org/uniprotkb/Q5DU41" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q5DU41", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5DU41" } ], "site_lbl": "Ser186" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "594", "end_pos": "594" }, { "start_pos": "78", "end_pos": "78" } ] }, { "type": "snv", "site_list": [ { "start_pos": "634", "end_pos": "634" }, { "start_pos": "646", "end_pos": "646" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "186", "end_pos": "186" }, { "start_pos": "196", "end_pos": "196" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "upstream", "id": "Q5DU41-1.196.196", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q5DU41-1.196.196", "start_pos": 196, "end_pos": 196, "uniprot_canonical_ac": "Q5DU41-1", "length": 803, "uniprot_id": "LRC8B_MOUSE", "protein_name": "Volume-regulated anion channel subunit LRRC8B", "refseq_ac": "NP_001028722", "refseq_name": "volume-regulated anion channel subunit LRRC8B", "gene_name": "Lrrc8b", "gene_names_uniprotkb": "Lrrc8b; Kiaa0231", "gene_names_refseq": "2210408K08Rik; Lrrc8b; Ta-lrrp; mKIAA0231", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q5DU41", "url": "https://www.uniprot.org/uniprotkb/Q5DU41" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q5DU41", "url": "https://www.uniprot.org/uniprotkb/Q5DU41" }, { "database": "iPTMnet", "id": "Q5DU41", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5DU41" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q5DU41", "url": "https://www.uniprot.org/uniprotkb/Q5DU41", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q5DU41", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5DU41", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QSVRPLKLSKSKTLLSTSGG", "down_seq": "ADIDASKQSLPYPQPGLESP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q5DU41", "url": "https://www.uniprot.org/uniprotkb/Q5DU41" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q5DU41", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5DU41" } ], "site_lbl": "Ser196" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "594", "end_pos": "594" }, { "start_pos": "78", "end_pos": "78" } ] }, { "type": "snv", "site_list": [ { "start_pos": "634", "end_pos": "634" }, { "start_pos": "646", "end_pos": "646" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "186", "end_pos": "186" }, { "start_pos": "196", "end_pos": "196" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "Q5DU41-1.186.186", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q80WG5-1.592.592", "start_pos": 592, "end_pos": 592, "uniprot_canonical_ac": "Q80WG5-1", "length": 810, "uniprot_id": "LRC8A_MOUSE", "protein_name": "Volume-regulated anion channel subunit LRRC8A", "refseq_ac": "NP_808393", "refseq_name": "volume-regulated anion channel subunit LRRC8A", "gene_name": "Lrrc8a", "gene_names_uniprotkb": "Lrrc8a; Lrrc8; Swell1", "gene_names_refseq": "Lrrc8a; Lrrc8; SWELL1; ebo; mKIAA1437", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80WG5", "url": "https://www.uniprot.org/uniprotkb/Q80WG5" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "LSINNEGTKLIVLNSLKKMV", "down_seq": "LTELELIRCDLERIPHSIFS", "glycosylation": [ { "glytoucan_ac": "G02815KT", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "MVNLTELELIR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn592", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "592", "end_pos": "592" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "89", "end_pos": "89" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" } ] }, { "type": "snv", "site_list": [ { "start_pos": "66", "end_pos": "66" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "200", "end_pos": "200" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "217", "end_pos": "217" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q80WG5-1.66.66", "start_pos": 66, "end_pos": 66, "uniprot_canonical_ac": "Q80WG5-1", "length": 810, "uniprot_id": "LRC8A_MOUSE", "protein_name": "Volume-regulated anion channel subunit LRRC8A", "refseq_ac": "NP_808393", "refseq_name": "volume-regulated anion channel subunit LRRC8A", "gene_name": "Lrrc8a", "gene_names_uniprotkb": "Lrrc8a; Lrrc8; Swell1", "gene_names_refseq": "Lrrc8a; Lrrc8; SWELL1; ebo; mKIAA1437", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80WG5", "url": "https://www.uniprot.org/uniprotkb/Q80WG5" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "Q80WG5", "url": "https://www.uniprot.org/uniprotkb/Q80WG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "rs3388543714", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388543714", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "QVTQDKMICLPCKWVTKDSC", "down_seq": "DSFRGWAASSPEPTYPNSTV", "glycosylation": [ { "glytoucan_ac": "G70619PT", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "WVTKDSCNDSFR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn66", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn66", "evidence": [ { "id": "Q80WG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q80WG5#ptm_processing" } ] } ], "snv": [ { "evidence": [ { "id": "rs3388543714", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388543714" } ], "glycoeffect": [ "n-glyco-sequon-loss" ], "sequence_org": "N", "sequence_mut": "S", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-loss (NDS->SDS).", "chr_id": "2", "chr_pos": "30145384", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "N66", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "592", "end_pos": "592" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "89", "end_pos": "89" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" } ] }, { "type": "snv", "site_list": [ { "start_pos": "66", "end_pos": "66" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "200", "end_pos": "200" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "217", "end_pos": "217" } ] } ], "categories": [ "glycosylation_flag", "snv_flag" ], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "Q80WG5-1.47.47", "categories": [ "mutagenesis_flag" ] }, { "distance": 18, "direction": "downstream", "id": "Q80WG5-1.48.48", "categories": [ "mutagenesis_flag" ] }, { "distance": 17, "direction": "upstream", "id": "Q80WG5-1.83.83", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q80WG5-1.83.83", "start_pos": 83, "end_pos": 83, "uniprot_canonical_ac": "Q80WG5-1", "length": 810, "uniprot_id": "LRC8A_MOUSE", "protein_name": "Volume-regulated anion channel subunit LRRC8A", "refseq_ac": "NP_808393", "refseq_name": "volume-regulated anion channel subunit LRRC8A", "gene_name": "Lrrc8a", "gene_names_uniprotkb": "Lrrc8a; Lrrc8; Swell1", "gene_names_refseq": "Lrrc8a; Lrrc8; SWELL1; ebo; mKIAA1437", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80WG5", "url": "https://www.uniprot.org/uniprotkb/Q80WG5" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q80WG5", "url": "https://www.uniprot.org/uniprotkb/Q80WG5", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "DSCNDSFRGWAASSPEPTYP", "down_seq": "STVLPTPDTGPTGIKYDLDR", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn83", "evidence": [ { "id": "Q80WG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q80WG5#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "592", "end_pos": "592" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "89", "end_pos": "89" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" } ] }, { "type": "snv", "site_list": [ { "start_pos": "66", "end_pos": "66" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "200", "end_pos": "200" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "217", "end_pos": "217" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "Q80WG5-1.66.66", "categories": [ "glycosylation_flag", "snv_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q80WG5-1.89.89", "categories": [ "glycosylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "Q80WG5-1.103.103", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q80WG5-1.89.89", "start_pos": 89, "end_pos": 89, "uniprot_canonical_ac": "Q80WG5-1", "length": 810, "uniprot_id": "LRC8A_MOUSE", "protein_name": "Volume-regulated anion channel subunit LRRC8A", "refseq_ac": "NP_808393", "refseq_name": "volume-regulated anion channel subunit LRRC8A", "gene_name": "Lrrc8a", "gene_names_uniprotkb": "Lrrc8a; Lrrc8; Swell1", "gene_names_refseq": "Lrrc8a; Lrrc8; SWELL1; ebo; mKIAA1437", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80WG5", "url": "https://www.uniprot.org/uniprotkb/Q80WG5" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "FRGWAASSPEPTYPNSTVLP", "down_seq": "PDTGPTGIKYDLDRHQYNYV", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr89", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "592", "end_pos": "592" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "89", "end_pos": "89" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" } ] }, { "type": "snv", "site_list": [ { "start_pos": "66", "end_pos": "66" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "200", "end_pos": "200" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "217", "end_pos": "217" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "Q80WG5-1.83.83", "categories": [ "glycosylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q80WG5-1.103.103", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q80WG5-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "Q80WG5-1", "length": 810, "uniprot_id": "LRC8A_MOUSE", "protein_name": "Volume-regulated anion channel subunit LRRC8A", "refseq_ac": "NP_808393", "refseq_name": "volume-regulated anion channel subunit LRRC8A", "gene_name": "Lrrc8a", "gene_names_uniprotkb": "Lrrc8a; Lrrc8; Swell1", "gene_names_refseq": "Lrrc8a; Lrrc8; SWELL1; ebo; mKIAA1437", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80WG5", "url": "https://www.uniprot.org/uniprotkb/Q80WG5" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q80WG5", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q80WG5" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] } ], "crossref": [ { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q80WG5", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q80WG5", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" }, { "id": "Q80WG5", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q80WG5" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "592", "end_pos": "592" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "89", "end_pos": "89" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" } ] }, { "type": "snv", "site_list": [ { "start_pos": "66", "end_pos": "66" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "200", "end_pos": "200" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "217", "end_pos": "217" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q80WG5-1.103.103", "start_pos": 103, "end_pos": 103, "uniprot_canonical_ac": "Q80WG5-1", "length": 810, "uniprot_id": "LRC8A_MOUSE", "protein_name": "Volume-regulated anion channel subunit LRRC8A", "refseq_ac": "NP_808393", "refseq_name": "volume-regulated anion channel subunit LRRC8A", "gene_name": "Lrrc8a", "gene_names_uniprotkb": "Lrrc8a; Lrrc8; Swell1", "gene_names_refseq": "Lrrc8a; Lrrc8; SWELL1; ebo; mKIAA1437", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80WG5", "url": "https://www.uniprot.org/uniprotkb/Q80WG5" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Structure of a volume-regulated anion channel of the LRRC8 family.", "journal": "Nature", "date": "2018", "authors": "Deneka D, Sawicka M, Lam AKM, Paulino C, Dutzler R", "evidence": [ { "database": "UniProtKB", "id": "Q80WG5", "url": "https://www.uniprot.org/uniprotkb/Q80WG5" } ], "reference": [ { "type": "PubMed", "id": "29769723", "url": "https://glygen.org/publication/PubMed/29769723" } ] } ], "crossref": [ { "id": "Q80WG5", "url": "https://www.uniprot.org/uniprotkb/Q80WG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "29769723", "url": "https://glygen.org/publication/PubMed/29769723", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "NSTVLPTPDTGPTGIKYDLD", "down_seq": "HQYNYVDAVCYENRLHWFAK", "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "No effect on anion channel activity. Impairs channel selectivity, so that the channel is also permeable to Na(+) ions.", "evidence": [ { "database": "UniProtKB", "id": "Q80WG5", "url": "https://www.uniprot.org/uniprotkb/Q80WG5" }, { "database": "PubMed", "id": "29769723", "url": "https://glygen.org/publication/PubMed/29769723" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "592", "end_pos": "592" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "89", "end_pos": "89" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" } ] }, { "type": "snv", "site_list": [ { "start_pos": "66", "end_pos": "66" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "200", "end_pos": "200" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "217", "end_pos": "217" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "Q80WG5-1.83.83", "categories": [ "glycosylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "Q80WG5-1.89.89", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q80WG5-1.40.40", "start_pos": 40, "end_pos": 40, "uniprot_canonical_ac": "Q80WG5-1", "length": 810, "uniprot_id": "LRC8A_MOUSE", "protein_name": "Volume-regulated anion channel subunit LRRC8A", "refseq_ac": "NP_808393", "refseq_name": "volume-regulated anion channel subunit LRRC8A", "gene_name": "Lrrc8a", "gene_names_uniprotkb": "Lrrc8a; Lrrc8; Swell1", "gene_names_refseq": "Lrrc8a; Lrrc8; SWELL1; ebo; mKIAA1437", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80WG5", "url": "https://www.uniprot.org/uniprotkb/Q80WG5" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Structural basis for assembly and lipid-mediated gating of LRRC8A:C volume-regulated anion channels.", "journal": "Nature structural & molecular biology", "date": "2023-06", "authors": "Kern David M, Bleier Julia, Mukherjee Somnath, Hill Jennifer M, Kossiakoff Anthony A, Isacoff Ehud Y, Brohawn Stephen G", "evidence": [ { "database": "UniProtKB", "id": "Q80WG5", "url": "https://www.uniprot.org/uniprotkb/Q80WG5" } ], "reference": [ { "type": "PubMed", "id": "36928458", "url": "https://glygen.org/publication/PubMed/36928458" } ] } ], "crossref": [ { "id": "Q80WG5", "url": "https://www.uniprot.org/uniprotkb/Q80WG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "36928458", "url": "https://glygen.org/publication/PubMed/36928458", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "V", "start_aa": "V", "up_seq": "LKPWWDVFTDYISIVMLMIA", "down_seq": "FGGTLQVTQDKMICLPCKWV", "mutagenesis": [ { "sequence_org": "V", "sequence_mut": "D", "comment": "Abolishes activity in hypotonic solution.", "evidence": [ { "database": "UniProtKB", "id": "Q80WG5", "url": "https://www.uniprot.org/uniprotkb/Q80WG5" }, { "database": "PubMed", "id": "36928458", "url": "https://glygen.org/publication/PubMed/36928458" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "592", "end_pos": "592" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "89", "end_pos": "89" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" } ] }, { "type": "snv", "site_list": [ { "start_pos": "66", "end_pos": "66" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "200", "end_pos": "200" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "217", "end_pos": "217" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "Q80WG5-1.44.44", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q80WG5-1.47.47", "categories": [ "mutagenesis_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q80WG5-1.48.48", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q80WG5-1.44.44", "start_pos": 44, "end_pos": 44, "uniprot_canonical_ac": "Q80WG5-1", "length": 810, "uniprot_id": "LRC8A_MOUSE", "protein_name": "Volume-regulated anion channel subunit LRRC8A", "refseq_ac": "NP_808393", "refseq_name": "volume-regulated anion channel subunit LRRC8A", "gene_name": "Lrrc8a", "gene_names_uniprotkb": "Lrrc8a; Lrrc8; Swell1", "gene_names_refseq": "Lrrc8a; Lrrc8; SWELL1; ebo; mKIAA1437", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80WG5", "url": "https://www.uniprot.org/uniprotkb/Q80WG5" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Structural basis for assembly and lipid-mediated gating of LRRC8A:C volume-regulated anion channels.", "journal": "Nature structural & molecular biology", "date": "2023-06", "authors": "Kern David M, Bleier Julia, Mukherjee Somnath, Hill Jennifer M, Kossiakoff Anthony A, Isacoff Ehud Y, Brohawn Stephen G", "evidence": [ { "database": "UniProtKB", "id": "Q80WG5", "url": "https://www.uniprot.org/uniprotkb/Q80WG5" } ], "reference": [ { "type": "PubMed", "id": "36928458", "url": "https://glygen.org/publication/PubMed/36928458" } ] } ], "crossref": [ { "id": "Q80WG5", "url": "https://www.uniprot.org/uniprotkb/Q80WG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "36928458", "url": "https://glygen.org/publication/PubMed/36928458", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "WDVFTDYISIVMLMIAVFGG", "down_seq": "LQVTQDKMICLPCKWVTKDS", "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "D", "comment": "Abolishes activity in hypotonic solution.", "evidence": [ { "database": "UniProtKB", "id": "Q80WG5", "url": "https://www.uniprot.org/uniprotkb/Q80WG5" }, { "database": "PubMed", "id": "36928458", "url": "https://glygen.org/publication/PubMed/36928458" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "592", "end_pos": "592" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "89", "end_pos": "89" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" } ] }, { "type": "snv", "site_list": [ { "start_pos": "66", "end_pos": "66" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "200", "end_pos": "200" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "217", "end_pos": "217" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "Q80WG5-1.40.40", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q80WG5-1.47.47", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q80WG5-1.48.48", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q80WG5-1.47.47", "start_pos": 47, "end_pos": 47, "uniprot_canonical_ac": "Q80WG5-1", "length": 810, "uniprot_id": "LRC8A_MOUSE", "protein_name": "Volume-regulated anion channel subunit LRRC8A", "refseq_ac": "NP_808393", "refseq_name": "volume-regulated anion channel subunit LRRC8A", "gene_name": "Lrrc8a", "gene_names_uniprotkb": "Lrrc8a; Lrrc8; Swell1", "gene_names_refseq": "Lrrc8a; Lrrc8; SWELL1; ebo; mKIAA1437", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80WG5", "url": "https://www.uniprot.org/uniprotkb/Q80WG5" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Structural basis for assembly and lipid-mediated gating of LRRC8A:C volume-regulated anion channels.", "journal": "Nature structural & molecular biology", "date": "2023-06", "authors": "Kern David M, Bleier Julia, Mukherjee Somnath, Hill Jennifer M, Kossiakoff Anthony A, Isacoff Ehud Y, Brohawn Stephen G", "evidence": [ { "database": "UniProtKB", "id": "Q80WG5", "url": "https://www.uniprot.org/uniprotkb/Q80WG5" } ], "reference": [ { "type": "PubMed", "id": "36928458", "url": "https://glygen.org/publication/PubMed/36928458" } ] } ], "crossref": [ { "id": "Q80WG5", "url": "https://www.uniprot.org/uniprotkb/Q80WG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "36928458", "url": "https://glygen.org/publication/PubMed/36928458", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "V", "start_aa": "V", "up_seq": "FTDYISIVMLMIAVFGGTLQ", "down_seq": "TQDKMICLPCKWVTKDSCND", "mutagenesis": [ { "sequence_org": "V", "sequence_mut": "D", "comment": "Abolishes activity in hypotonic solution.", "evidence": [ { "database": "UniProtKB", "id": "Q80WG5", "url": "https://www.uniprot.org/uniprotkb/Q80WG5" }, { "database": "PubMed", "id": "36928458", "url": "https://glygen.org/publication/PubMed/36928458" } ] }, { "sequence_org": "V", "sequence_mut": "K", "comment": "Impairs activity in hypotonic solution.", "evidence": [ { "database": "UniProtKB", "id": "Q80WG5", "url": "https://www.uniprot.org/uniprotkb/Q80WG5" }, { "database": "PubMed", "id": "36928458", "url": "https://glygen.org/publication/PubMed/36928458" } ] }, { "sequence_org": "V", "sequence_mut": "N", "comment": "Impairs activity in hypotonic solution.", "evidence": [ { "database": "UniProtKB", "id": "Q80WG5", "url": "https://www.uniprot.org/uniprotkb/Q80WG5" }, { "database": "PubMed", "id": "36928458", "url": "https://glygen.org/publication/PubMed/36928458" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "592", "end_pos": "592" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "89", "end_pos": "89" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" } ] }, { "type": "snv", "site_list": [ { "start_pos": "66", "end_pos": "66" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "200", "end_pos": "200" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "217", "end_pos": "217" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "Q80WG5-1.40.40", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q80WG5-1.44.44", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q80WG5-1.48.48", "categories": [ "mutagenesis_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q80WG5-1.66.66", "categories": [ "glycosylation_flag", "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q80WG5-1.48.48", "start_pos": 48, "end_pos": 48, "uniprot_canonical_ac": "Q80WG5-1", "length": 810, "uniprot_id": "LRC8A_MOUSE", "protein_name": "Volume-regulated anion channel subunit LRRC8A", "refseq_ac": "NP_808393", "refseq_name": "volume-regulated anion channel subunit LRRC8A", "gene_name": "Lrrc8a", "gene_names_uniprotkb": "Lrrc8a; Lrrc8; Swell1", "gene_names_refseq": "Lrrc8a; Lrrc8; SWELL1; ebo; mKIAA1437", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80WG5", "url": "https://www.uniprot.org/uniprotkb/Q80WG5" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Structural basis for assembly and lipid-mediated gating of LRRC8A:C volume-regulated anion channels.", "journal": "Nature structural & molecular biology", "date": "2023-06", "authors": "Kern David M, Bleier Julia, Mukherjee Somnath, Hill Jennifer M, Kossiakoff Anthony A, Isacoff Ehud Y, Brohawn Stephen G", "evidence": [ { "database": "UniProtKB", "id": "Q80WG5", "url": "https://www.uniprot.org/uniprotkb/Q80WG5" } ], "reference": [ { "type": "PubMed", "id": "36928458", "url": "https://glygen.org/publication/PubMed/36928458" } ] } ], "crossref": [ { "id": "Q80WG5", "url": "https://www.uniprot.org/uniprotkb/Q80WG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "36928458", "url": "https://glygen.org/publication/PubMed/36928458", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "TDYISIVMLMIAVFGGTLQV", "down_seq": "QDKMICLPCKWVTKDSCNDS", "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "D", "comment": "Abolishes activity in hypotonic solution.", "evidence": [ { "database": "UniProtKB", "id": "Q80WG5", "url": "https://www.uniprot.org/uniprotkb/Q80WG5" }, { "database": "PubMed", "id": "36928458", "url": "https://glygen.org/publication/PubMed/36928458" } ] }, { "sequence_org": "T", "sequence_mut": "K", "comment": "Impairs activity in hypotonic solution.", "evidence": [ { "database": "UniProtKB", "id": "Q80WG5", "url": "https://www.uniprot.org/uniprotkb/Q80WG5" }, { "database": "PubMed", "id": "36928458", "url": "https://glygen.org/publication/PubMed/36928458" } ] }, { "sequence_org": "T", "sequence_mut": "N", "comment": "Impairs activity in hypotonic solution.", "evidence": [ { "database": "UniProtKB", "id": "Q80WG5", "url": "https://www.uniprot.org/uniprotkb/Q80WG5" }, { "database": "PubMed", "id": "36928458", "url": "https://glygen.org/publication/PubMed/36928458" } ] }, { "sequence_org": "T", "sequence_mut": "W", "comment": "Impairs activity in hypotonic solution.", "evidence": [ { "database": "UniProtKB", "id": "Q80WG5", "url": "https://www.uniprot.org/uniprotkb/Q80WG5" }, { "database": "PubMed", "id": "36928458", "url": "https://glygen.org/publication/PubMed/36928458" } ] }, { "sequence_org": "T", "sequence_mut": "Y", "comment": "Impairs activity in hypotonic solution.", "evidence": [ { "database": "UniProtKB", "id": "Q80WG5", "url": "https://www.uniprot.org/uniprotkb/Q80WG5" }, { "database": "PubMed", "id": "36928458", "url": "https://glygen.org/publication/PubMed/36928458" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "592", "end_pos": "592" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "89", "end_pos": "89" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" } ] }, { "type": "snv", "site_list": [ { "start_pos": "66", "end_pos": "66" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "200", "end_pos": "200" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "217", "end_pos": "217" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "Q80WG5-1.40.40", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q80WG5-1.44.44", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q80WG5-1.47.47", "categories": [ "mutagenesis_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q80WG5-1.66.66", "categories": [ "glycosylation_flag", "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q80WG5-1.200.200", "start_pos": 200, "end_pos": 200, "uniprot_canonical_ac": "Q80WG5-1", "length": 810, "uniprot_id": "LRC8A_MOUSE", "protein_name": "Volume-regulated anion channel subunit LRRC8A", "refseq_ac": "NP_808393", "refseq_name": "volume-regulated anion channel subunit LRRC8A", "gene_name": "Lrrc8a", "gene_names_uniprotkb": "Lrrc8a; Lrrc8; Swell1", "gene_names_refseq": "Lrrc8a; Lrrc8; SWELL1; ebo; mKIAA1437", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80WG5", "url": "https://www.uniprot.org/uniprotkb/Q80WG5" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q80WG5", "url": "https://www.uniprot.org/uniprotkb/Q80WG5" }, { "database": "iPTMnet", "id": "Q80WG5", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80WG5" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q80WG5", "url": "https://www.uniprot.org/uniprotkb/Q80WG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q80WG5", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80WG5", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "ESDPKPAFSKMNGSMDKKSS", "down_seq": "VSEDVEATVPMLQRTKSRIE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q80WG5", "url": "https://www.uniprot.org/uniprotkb/Q80WG5" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q80WG5", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80WG5" } ], "site_lbl": "Thr200" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "592", "end_pos": "592" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "89", "end_pos": "89" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" } ] }, { "type": "snv", "site_list": [ { "start_pos": "66", "end_pos": "66" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "200", "end_pos": "200" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "217", "end_pos": "217" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "Q80WG5-1.202.202", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q80WG5-1.215.215", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "Q80WG5-1.217.217", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q80WG5-1.202.202", "start_pos": 202, "end_pos": 202, "uniprot_canonical_ac": "Q80WG5-1", "length": 810, "uniprot_id": "LRC8A_MOUSE", "protein_name": "Volume-regulated anion channel subunit LRRC8A", "refseq_ac": "NP_808393", "refseq_name": "volume-regulated anion channel subunit LRRC8A", "gene_name": "Lrrc8a", "gene_names_uniprotkb": "Lrrc8a; Lrrc8; Swell1", "gene_names_refseq": "Lrrc8a; Lrrc8; SWELL1; ebo; mKIAA1437", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80WG5", "url": "https://www.uniprot.org/uniprotkb/Q80WG5" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q80WG5", "url": "https://www.uniprot.org/uniprotkb/Q80WG5" }, { "database": "iPTMnet", "id": "Q80WG5", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80WG5" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q80WG5", "url": "https://www.uniprot.org/uniprotkb/Q80WG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q80WG5", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80WG5", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DPKPAFSKMNGSMDKKSSTV", "down_seq": "EDVEATVPMLQRTKSRIEQG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q80WG5", "url": "https://www.uniprot.org/uniprotkb/Q80WG5" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q80WG5", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80WG5" } ], "site_lbl": "Ser202" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "592", "end_pos": "592" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "89", "end_pos": "89" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" } ] }, { "type": "snv", "site_list": [ { "start_pos": "66", "end_pos": "66" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "200", "end_pos": "200" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "217", "end_pos": "217" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "Q80WG5-1.200.200", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q80WG5-1.215.215", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q80WG5-1.217.217", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q80WG5-1.215.215", "start_pos": 215, "end_pos": 215, "uniprot_canonical_ac": "Q80WG5-1", "length": 810, "uniprot_id": "LRC8A_MOUSE", "protein_name": "Volume-regulated anion channel subunit LRRC8A", "refseq_ac": "NP_808393", "refseq_name": "volume-regulated anion channel subunit LRRC8A", "gene_name": "Lrrc8a", "gene_names_uniprotkb": "Lrrc8a; Lrrc8; Swell1", "gene_names_refseq": "Lrrc8a; Lrrc8; SWELL1; ebo; mKIAA1437", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80WG5", "url": "https://www.uniprot.org/uniprotkb/Q80WG5" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q80WG5", "url": "https://www.uniprot.org/uniprotkb/Q80WG5", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "DKKSSTVSEDVEATVPMLQR", "down_seq": "KSRIEQGIVDRSETGVLDKK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q80WG5", "url": "https://www.uniprot.org/uniprotkb/Q80WG5" } ], "site_lbl": "Thr215" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "592", "end_pos": "592" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "89", "end_pos": "89" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" } ] }, { "type": "snv", "site_list": [ { "start_pos": "66", "end_pos": "66" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "200", "end_pos": "200" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "217", "end_pos": "217" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "Q80WG5-1.200.200", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "Q80WG5-1.202.202", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q80WG5-1.217.217", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q80WG5-1.217.217", "start_pos": 217, "end_pos": 217, "uniprot_canonical_ac": "Q80WG5-1", "length": 810, "uniprot_id": "LRC8A_MOUSE", "protein_name": "Volume-regulated anion channel subunit LRRC8A", "refseq_ac": "NP_808393", "refseq_name": "volume-regulated anion channel subunit LRRC8A", "gene_name": "Lrrc8a", "gene_names_uniprotkb": "Lrrc8a; Lrrc8; Swell1", "gene_names_refseq": "Lrrc8a; Lrrc8; SWELL1; ebo; mKIAA1437", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80WG5", "url": "https://www.uniprot.org/uniprotkb/Q80WG5" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q80WG5", "url": "https://www.uniprot.org/uniprotkb/Q80WG5", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KSSTVSEDVEATVPMLQRTK", "down_seq": "RIEQGIVDRSETGVLDKKEG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q80WG5", "url": "https://www.uniprot.org/uniprotkb/Q80WG5" } ], "site_lbl": "Ser217" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "592", "end_pos": "592" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "89", "end_pos": "89" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" } ] }, { "type": "snv", "site_list": [ { "start_pos": "66", "end_pos": "66" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "200", "end_pos": "200" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "217", "end_pos": "217" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "Q80WG5-1.200.200", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "Q80WG5-1.202.202", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q80WG5-1.215.215", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q149C2-1.453.453", "start_pos": 453, "end_pos": 453, "uniprot_canonical_ac": "Q149C2-1", "length": 625, "uniprot_id": "MIPT3_MOUSE", "protein_name": "TRAF3-interacting protein 1", "refseq_ac": "NP_082994", "refseq_name": "TRAF3-interacting protein 1", "gene_name": "Traf3ip1", "gene_names_uniprotkb": "Traf3ip1; Ift54; Mipt3", "gene_names_refseq": "3930402D05Rik; MIP-T3; Traf3ip1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q149C2", "url": "https://www.uniprot.org/uniprotkb/Q149C2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q149C2", "url": "https://www.uniprot.org/uniprotkb/Q149C2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "I", "start_aa": "I", "up_seq": "NSDNEDDEQFVVEAAPQLSE", "down_seq": "ADIDMVPSGELEDEEKHGGL", "mutagenesis": [ { "sequence_org": "I", "sequence_mut": "R", "comment": "Decreased interaction with MAP4. No effect on interaction with IFT20.", "evidence": [ { "database": "UniProtKB", "id": "Q149C2", "url": "https://www.uniprot.org/uniprotkb/Q149C2" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "453", "end_pos": "453" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "316", "end_pos": "316" }, { "start_pos": "409", "end_pos": "409" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q149C2-1.316.316", "start_pos": 316, "end_pos": 316, "uniprot_canonical_ac": "Q149C2-1", "length": 625, "uniprot_id": "MIPT3_MOUSE", "protein_name": "TRAF3-interacting protein 1", "refseq_ac": "NP_082994", "refseq_name": "TRAF3-interacting protein 1", "gene_name": "Traf3ip1", "gene_names_uniprotkb": "Traf3ip1; Ift54; Mipt3", "gene_names_refseq": "3930402D05Rik; MIP-T3; Traf3ip1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q149C2", "url": "https://www.uniprot.org/uniprotkb/Q149C2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q149C2", "url": "https://www.uniprot.org/uniprotkb/Q149C2" }, { "database": "iPTMnet", "id": "Q149C2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q149C2" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q149C2", "url": "https://www.uniprot.org/uniprotkb/Q149C2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q149C2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q149C2", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RDADKPEKKSSSSGEISRKL", "down_seq": "DGSFKDVKAEMEADISVGAS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q149C2", "url": "https://www.uniprot.org/uniprotkb/Q149C2" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q149C2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q149C2" } ], "site_lbl": "Ser316" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "453", "end_pos": "453" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "316", "end_pos": "316" }, { "start_pos": "409", "end_pos": "409" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q149C2-1.409.409", "start_pos": 409, "end_pos": 409, "uniprot_canonical_ac": "Q149C2-1", "length": 625, "uniprot_id": "MIPT3_MOUSE", "protein_name": "TRAF3-interacting protein 1", "refseq_ac": "NP_082994", "refseq_name": "TRAF3-interacting protein 1", "gene_name": "Traf3ip1", "gene_names_uniprotkb": "Traf3ip1; Ift54; Mipt3", "gene_names_refseq": "3930402D05Rik; MIP-T3; Traf3ip1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q149C2", "url": "https://www.uniprot.org/uniprotkb/Q149C2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q149C2", "url": "https://www.uniprot.org/uniprotkb/Q149C2" }, { "database": "iPTMnet", "id": "Q149C2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q149C2" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q149C2", "url": "https://www.uniprot.org/uniprotkb/Q149C2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q149C2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q149C2", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RRIPRPGSARPAPPRVKRQE", "down_seq": "TETLVVDRSGSGKTVSSVII", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q149C2", "url": "https://www.uniprot.org/uniprotkb/Q149C2" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q149C2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q149C2" } ], "site_lbl": "Ser409" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "453", "end_pos": "453" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "316", "end_pos": "316" }, { "start_pos": "409", "end_pos": "409" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O35678-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "O35678-1", "length": 303, "uniprot_id": "MGLL_MOUSE", "protein_name": "Monoglyceride lipase", "refseq_ac": "NP_001159721", "refseq_name": "monoglyceride lipase isoform c", "gene_name": "Mgll", "gene_names_uniprotkb": "Mgll", "gene_names_refseq": "Magl; Mgll; Mgl", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O35678", "url": "https://www.uniprot.org/uniprotkb/O35678" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Differential Detection of O-GlcNAcylated proteins in the heart using antibodies.", "journal": "Analytical biochemistry", "date": "2023-10-01", "authors": "Narayanan Bhargavi, Zahra Fiddia, Reeves Russell A, Aggarwal Akanksha, O'Meally Robert N, Henry Roger K, Craven Megan, Jacobson Avital, Cole Robert N, Kohr Mark J, Umapathi Priya, Zachara Natasha E", "evidence": [ { "database": "O-GlcNAc Database", "id": "O35678", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O35678" } ], "reference": [ { "type": "PubMed", "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081" } ] } ], "crossref": [ { "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081", "database": "PubMed", "categories": [ "Other" ] }, { "id": "O35678", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O35678", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "37507081", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37507081" }, { "id": "O35678", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O35678" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "122", "end_pos": "122" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "272", "end_pos": "272" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "292", "end_pos": "292" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "10", "end_pos": "10" }, { "start_pos": "189", "end_pos": "189" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "upstream", "id": "O35678-1.10.10", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O35678-1.122.122", "start_pos": 122, "end_pos": 122, "uniprot_canonical_ac": "O35678-1", "length": 303, "uniprot_id": "MGLL_MOUSE", "protein_name": "Monoglyceride lipase", "refseq_ac": "NP_001159721", "refseq_name": "monoglyceride lipase isoform c", "gene_name": "Mgll", "gene_names_uniprotkb": "Mgll", "gene_names_refseq": "Magl; Mgll; Mgl", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O35678", "url": "https://www.uniprot.org/uniprotkb/O35678" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "cDNA cloning, tissue distribution, and identification of the catalytic triad of monoglyceride lipase. Evolutionary relationship to esterases, lysophospholipases, and haloperoxidases.", "journal": "The Journal of biological chemistry", "date": "1997", "authors": "Karlsson M, Contreras JA, Hellman U, Tornqvist H, Holm C", "evidence": [ { "database": "UniProtKB", "id": "O35678", "url": "https://www.uniprot.org/uniprotkb/O35678" } ], "reference": [ { "type": "PubMed", "id": "9341166", "url": "https://glygen.org/publication/PubMed/9341166" } ] } ], "crossref": [ { "id": "O35678", "url": "https://www.uniprot.org/uniprotkb/O35678", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "9341166", "url": "https://glygen.org/publication/PubMed/9341166", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QHVDTIQKDYPDVPIFLLGH", "down_seq": "MGGAISILVAAERPTYFSGM", "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Abolishes activity.", "evidence": [ { "database": "UniProtKB", "id": "O35678", "url": "https://www.uniprot.org/uniprotkb/O35678" }, { "database": "PubMed", "id": "9341166", "url": "https://glygen.org/publication/PubMed/9341166" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "122", "end_pos": "122" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "272", "end_pos": "272" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "292", "end_pos": "292" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "10", "end_pos": "10" }, { "start_pos": "189", "end_pos": "189" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O35678-1.239.239", "start_pos": 239, "end_pos": 239, "uniprot_canonical_ac": "O35678-1", "length": 303, "uniprot_id": "MGLL_MOUSE", "protein_name": "Monoglyceride lipase", "refseq_ac": "NP_001159721", "refseq_name": "monoglyceride lipase isoform c", "gene_name": "Mgll", "gene_names_uniprotkb": "Mgll", "gene_names_refseq": "Magl; Mgll; Mgl", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O35678", "url": "https://www.uniprot.org/uniprotkb/O35678" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "cDNA cloning, tissue distribution, and identification of the catalytic triad of monoglyceride lipase. Evolutionary relationship to esterases, lysophospholipases, and haloperoxidases.", "journal": "The Journal of biological chemistry", "date": "1997", "authors": "Karlsson M, Contreras JA, Hellman U, Tornqvist H, Holm C", "evidence": [ { "database": "UniProtKB", "id": "O35678", "url": "https://www.uniprot.org/uniprotkb/O35678" } ], "reference": [ { "type": "PubMed", "id": "9341166", "url": "https://glygen.org/publication/PubMed/9341166" } ] } ], "crossref": [ { "id": "O35678", "url": "https://www.uniprot.org/uniprotkb/O35678", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "9341166", "url": "https://glygen.org/publication/PubMed/9341166", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "RVERAMPRLTLPFLLLQGSA", "down_seq": "RLCDSKGAYLLMESSRSQDK", "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Abolishes activity.", "evidence": [ { "database": "UniProtKB", "id": "O35678", "url": "https://www.uniprot.org/uniprotkb/O35678" }, { "database": "PubMed", "id": "9341166", "url": "https://glygen.org/publication/PubMed/9341166" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "122", "end_pos": "122" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "272", "end_pos": "272" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "292", "end_pos": "292" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "10", "end_pos": "10" }, { "start_pos": "189", "end_pos": "189" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "O35678-1.243.243", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O35678-1.243.243", "start_pos": 243, "end_pos": 243, "uniprot_canonical_ac": "O35678-1", "length": 303, "uniprot_id": "MGLL_MOUSE", "protein_name": "Monoglyceride lipase", "refseq_ac": "NP_001159721", "refseq_name": "monoglyceride lipase isoform c", "gene_name": "Mgll", "gene_names_uniprotkb": "Mgll", "gene_names_refseq": "Magl; Mgll; Mgl", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O35678", "url": "https://www.uniprot.org/uniprotkb/O35678" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "cDNA cloning, tissue distribution, and identification of the catalytic triad of monoglyceride lipase. Evolutionary relationship to esterases, lysophospholipases, and haloperoxidases.", "journal": "The Journal of biological chemistry", "date": "1997", "authors": "Karlsson M, Contreras JA, Hellman U, Tornqvist H, Holm C", "evidence": [ { "database": "UniProtKB", "id": "O35678", "url": "https://www.uniprot.org/uniprotkb/O35678" } ], "reference": [ { "type": "PubMed", "id": "9341166", "url": "https://glygen.org/publication/PubMed/9341166" } ] } ], "crossref": [ { "id": "O35678", "url": "https://www.uniprot.org/uniprotkb/O35678", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "9341166", "url": "https://glygen.org/publication/PubMed/9341166", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "AMPRLTLPFLLLQGSADRLC", "down_seq": "SKGAYLLMESSRSQDKTLKM", "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Slightly reduces activity.", "evidence": [ { "database": "UniProtKB", "id": "O35678", "url": "https://www.uniprot.org/uniprotkb/O35678" }, { "database": "PubMed", "id": "9341166", "url": "https://glygen.org/publication/PubMed/9341166" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "122", "end_pos": "122" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "272", "end_pos": "272" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "292", "end_pos": "292" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "10", "end_pos": "10" }, { "start_pos": "189", "end_pos": "189" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "O35678-1.239.239", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O35678-1.269.269", "start_pos": 269, "end_pos": 269, "uniprot_canonical_ac": "O35678-1", "length": 303, "uniprot_id": "MGLL_MOUSE", "protein_name": "Monoglyceride lipase", "refseq_ac": "NP_001159721", "refseq_name": "monoglyceride lipase isoform c", "gene_name": "Mgll", "gene_names_uniprotkb": "Mgll", "gene_names_refseq": "Magl; Mgll; Mgl", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O35678", "url": "https://www.uniprot.org/uniprotkb/O35678" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "cDNA cloning, tissue distribution, and identification of the catalytic triad of monoglyceride lipase. Evolutionary relationship to esterases, lysophospholipases, and haloperoxidases.", "journal": "The Journal of biological chemistry", "date": "1997", "authors": "Karlsson M, Contreras JA, Hellman U, Tornqvist H, Holm C", "evidence": [ { "database": "UniProtKB", "id": "O35678", "url": "https://www.uniprot.org/uniprotkb/O35678" } ], "reference": [ { "type": "PubMed", "id": "9341166", "url": "https://glygen.org/publication/PubMed/9341166" } ] } ], "crossref": [ { "id": "O35678", "url": "https://www.uniprot.org/uniprotkb/O35678", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "9341166", "url": "https://glygen.org/publication/PubMed/9341166", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "H", "start_aa": "H", "up_seq": "LLMESSRSQDKTLKMYEGAY", "down_seq": "VLHRELPEVTNSVLHEVNSW", "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Abolishes activity.", "evidence": [ { "database": "UniProtKB", "id": "O35678", "url": "https://www.uniprot.org/uniprotkb/O35678" }, { "database": "PubMed", "id": "9341166", "url": "https://glygen.org/publication/PubMed/9341166" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "122", "end_pos": "122" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "272", "end_pos": "272" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "292", "end_pos": "292" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "10", "end_pos": "10" }, { "start_pos": "189", "end_pos": "189" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "O35678-1.272.272", "categories": [ "mutagenesis_flag" ] }, { "distance": 15, "direction": "upstream", "id": "O35678-1.284.284", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O35678-1.272.272", "start_pos": 272, "end_pos": 272, "uniprot_canonical_ac": "O35678-1", "length": 303, "uniprot_id": "MGLL_MOUSE", "protein_name": "Monoglyceride lipase", "refseq_ac": "NP_001159721", "refseq_name": "monoglyceride lipase isoform c", "gene_name": "Mgll", "gene_names_uniprotkb": "Mgll", "gene_names_refseq": "Magl; Mgll; Mgl", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O35678", "url": "https://www.uniprot.org/uniprotkb/O35678" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "cDNA cloning, tissue distribution, and identification of the catalytic triad of monoglyceride lipase. Evolutionary relationship to esterases, lysophospholipases, and haloperoxidases.", "journal": "The Journal of biological chemistry", "date": "1997", "authors": "Karlsson M, Contreras JA, Hellman U, Tornqvist H, Holm C", "evidence": [ { "database": "UniProtKB", "id": "O35678", "url": "https://www.uniprot.org/uniprotkb/O35678" } ], "reference": [ { "type": "PubMed", "id": "9341166", "url": "https://glygen.org/publication/PubMed/9341166" } ] } ], "crossref": [ { "id": "O35678", "url": "https://www.uniprot.org/uniprotkb/O35678", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "9341166", "url": "https://glygen.org/publication/PubMed/9341166", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "H", "start_aa": "H", "up_seq": "ESSRSQDKTLKMYEGAYHVL", "down_seq": "RELPEVTNSVLHEVNSWVSH", "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Reduces activity.", "evidence": [ { "database": "UniProtKB", "id": "O35678", "url": "https://www.uniprot.org/uniprotkb/O35678" }, { "database": "PubMed", "id": "9341166", "url": "https://glygen.org/publication/PubMed/9341166" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "122", "end_pos": "122" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "272", "end_pos": "272" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "292", "end_pos": "292" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "10", "end_pos": "10" }, { "start_pos": "189", "end_pos": "189" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "O35678-1.269.269", "categories": [ "mutagenesis_flag" ] }, { "distance": 12, "direction": "upstream", "id": "O35678-1.284.284", "categories": [ "mutagenesis_flag" ] }, { "distance": 20, "direction": "upstream", "id": "O35678-1.292.292", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O35678-1.284.284", "start_pos": 284, "end_pos": 284, "uniprot_canonical_ac": "O35678-1", "length": 303, "uniprot_id": "MGLL_MOUSE", "protein_name": "Monoglyceride lipase", "refseq_ac": "NP_001159721", "refseq_name": "monoglyceride lipase isoform c", "gene_name": "Mgll", "gene_names_uniprotkb": "Mgll", "gene_names_refseq": "Magl; Mgll; Mgl", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O35678", "url": "https://www.uniprot.org/uniprotkb/O35678" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "cDNA cloning, tissue distribution, and identification of the catalytic triad of monoglyceride lipase. Evolutionary relationship to esterases, lysophospholipases, and haloperoxidases.", "journal": "The Journal of biological chemistry", "date": "1997", "authors": "Karlsson M, Contreras JA, Hellman U, Tornqvist H, Holm C", "evidence": [ { "database": "UniProtKB", "id": "O35678", "url": "https://www.uniprot.org/uniprotkb/O35678" } ], "reference": [ { "type": "PubMed", "id": "9341166", "url": "https://glygen.org/publication/PubMed/9341166" } ] } ], "crossref": [ { "id": "O35678", "url": "https://www.uniprot.org/uniprotkb/O35678", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "9341166", "url": "https://glygen.org/publication/PubMed/9341166", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "H", "start_aa": "H", "up_seq": "YEGAYHVLHRELPEVTNSVL", "down_seq": "EVNSWVSHRIAAAGAGCPP", "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Slightly reduces activity.", "evidence": [ { "database": "UniProtKB", "id": "O35678", "url": "https://www.uniprot.org/uniprotkb/O35678" }, { "database": "PubMed", "id": "9341166", "url": "https://glygen.org/publication/PubMed/9341166" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "122", "end_pos": "122" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "272", "end_pos": "272" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "292", "end_pos": "292" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "10", "end_pos": "10" }, { "start_pos": "189", "end_pos": "189" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "O35678-1.269.269", "categories": [ "mutagenesis_flag" ] }, { "distance": 12, "direction": "downstream", "id": "O35678-1.272.272", "categories": [ "mutagenesis_flag" ] }, { "distance": 8, "direction": "upstream", "id": "O35678-1.292.292", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O35678-1.292.292", "start_pos": 292, "end_pos": 292, "uniprot_canonical_ac": "O35678-1", "length": 303, "uniprot_id": "MGLL_MOUSE", "protein_name": "Monoglyceride lipase", "refseq_ac": "NP_001159721", "refseq_name": "monoglyceride lipase isoform c", "gene_name": "Mgll", "gene_names_uniprotkb": "Mgll", "gene_names_refseq": "Magl; Mgll; Mgl", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O35678", "url": "https://www.uniprot.org/uniprotkb/O35678" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "cDNA cloning, tissue distribution, and identification of the catalytic triad of monoglyceride lipase. Evolutionary relationship to esterases, lysophospholipases, and haloperoxidases.", "journal": "The Journal of biological chemistry", "date": "1997", "authors": "Karlsson M, Contreras JA, Hellman U, Tornqvist H, Holm C", "evidence": [ { "database": "UniProtKB", "id": "O35678", "url": "https://www.uniprot.org/uniprotkb/O35678" } ], "reference": [ { "type": "PubMed", "id": "9341166", "url": "https://glygen.org/publication/PubMed/9341166" } ] } ], "crossref": [ { "id": "O35678", "url": "https://www.uniprot.org/uniprotkb/O35678", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "9341166", "url": "https://glygen.org/publication/PubMed/9341166", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "H", "start_aa": "H", "up_seq": "HRELPEVTNSVLHEVNSWVS", "down_seq": "RIAAAGAGCPP", "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Slightly reduces activity.", "evidence": [ { "database": "UniProtKB", "id": "O35678", "url": "https://www.uniprot.org/uniprotkb/O35678" }, { "database": "PubMed", "id": "9341166", "url": "https://glygen.org/publication/PubMed/9341166" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "122", "end_pos": "122" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "272", "end_pos": "272" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "292", "end_pos": "292" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "10", "end_pos": "10" }, { "start_pos": "189", "end_pos": "189" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "O35678-1.272.272", "categories": [ "mutagenesis_flag" ] }, { "distance": 8, "direction": "downstream", "id": "O35678-1.284.284", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O35678-1.10.10", "start_pos": 10, "end_pos": 10, "uniprot_canonical_ac": "O35678-1", "length": 303, "uniprot_id": "MGLL_MOUSE", "protein_name": "Monoglyceride lipase", "refseq_ac": "NP_001159721", "refseq_name": "monoglyceride lipase isoform c", "gene_name": "Mgll", "gene_names_uniprotkb": "Mgll", "gene_names_refseq": "Magl; Mgll; Mgl", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O35678", "url": "https://www.uniprot.org/uniprotkb/O35678" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "O35678", "url": "https://www.uniprot.org/uniprotkb/O35678" }, { "database": "iPTMnet", "id": "O35678", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O35678" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "O35678", "url": "https://www.uniprot.org/uniprotkb/O35678", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "O35678", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O35678", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "MPEASSPRR", "down_seq": "PQNVPYQDLPHLVNADGQYL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "O35678", "url": "https://www.uniprot.org/uniprotkb/O35678" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "O35678", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O35678" } ], "site_lbl": "Thr10" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "122", "end_pos": "122" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "272", "end_pos": "272" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "292", "end_pos": "292" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "10", "end_pos": "10" }, { "start_pos": "189", "end_pos": "189" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "O35678-1.0.0", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O35678-1.189.189", "start_pos": 189, "end_pos": 189, "uniprot_canonical_ac": "O35678-1", "length": 303, "uniprot_id": "MGLL_MOUSE", "protein_name": "Monoglyceride lipase", "refseq_ac": "NP_001159721", "refseq_name": "monoglyceride lipase isoform c", "gene_name": "Mgll", "gene_names_uniprotkb": "Mgll", "gene_names_refseq": "Magl; Mgll; Mgl", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O35678", "url": "https://www.uniprot.org/uniprotkb/O35678" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "O35678", "url": "https://www.uniprot.org/uniprotkb/O35678" }, { "database": "iPTMnet", "id": "O35678", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O35678" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "O35678", "url": "https://www.uniprot.org/uniprotkb/O35678", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "O35678", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O35678", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "FVLPNMTLGRIDSSVLSRNK", "down_seq": "EVDLYNSDPLVCRAGLKVCF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O35678", "url": "https://www.uniprot.org/uniprotkb/O35678" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "O35678", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O35678" } ], "site_lbl": "Ser189" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "122", "end_pos": "122" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "272", "end_pos": "272" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "292", "end_pos": "292" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "10", "end_pos": "10" }, { "start_pos": "189", "end_pos": "189" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q3UIK4-1.399.399", "start_pos": 399, "end_pos": 399, "uniprot_canonical_ac": "Q3UIK4-1", "length": 456, "uniprot_id": "MET14_MOUSE", "protein_name": "N(6)-adenosine-methyltransferase non-catalytic subunit METTL14", "refseq_ac": "NP_964000", "refseq_name": "N(6)-adenosine-methyltransferase non-catalytic subunit METTL14", "gene_name": "Mettl14", "gene_names_uniprotkb": "Mettl14; Kiaa1627", "gene_names_refseq": "G430022H21Rik; Mettl14; mKIAA1627", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3UIK4", "url": "https://www.uniprot.org/uniprotkb/Q3UIK4" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q3UIK4", "url": "https://www.uniprot.org/uniprotkb/Q3UIK4", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SAPNSYLTGCTEEIERLRPK", "down_seq": "PPPKSKSDRGGGAPRGGGRG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3UIK4", "url": "https://www.uniprot.org/uniprotkb/Q3UIK4" } ], "site_lbl": "Ser399" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8R516-1.47.47", "start_pos": 47, "end_pos": 47, "uniprot_canonical_ac": "Q8R516-1", "length": 973, "uniprot_id": "MIB2_MOUSE", "protein_name": "E3 ubiquitin-protein ligase MIB2", "refseq_ac": "NP_001243037", "refseq_name": "E3 ubiquitin-protein ligase MIB2 isoform 2", "gene_name": "Mib2", "gene_names_uniprotkb": "Mib2; Skd", "gene_names_refseq": "2210008I11Rik; Mib2; Zzank1; skd", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8R516", "url": "https://www.uniprot.org/uniprotkb/Q8R516" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "DGGEGGVGTVVELGRHGSPS", "down_seq": "PDRTVVVQWDQGTRTNYRAG", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr47", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "47", "end_pos": "47" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "874", "end_pos": "874" }, { "start_pos": "951", "end_pos": "951" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "251", "end_pos": "251" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8R516-1.874.874", "start_pos": 874, "end_pos": 874, "uniprot_canonical_ac": "Q8R516-1", "length": 973, "uniprot_id": "MIB2_MOUSE", "protein_name": "E3 ubiquitin-protein ligase MIB2", "refseq_ac": "NP_001243037", "refseq_name": "E3 ubiquitin-protein ligase MIB2 isoform 2", "gene_name": "Mib2", "gene_names_uniprotkb": "Mib2; Skd", "gene_names_refseq": "2210008I11Rik; Mib2; Zzank1; skd", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8R516", "url": "https://www.uniprot.org/uniprotkb/Q8R516" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Mind bomb-2 is an E3 ligase for Notch ligand.", "journal": "The Journal of biological chemistry", "date": "2005", "authors": "Koo BK, Yoon KJ, Yoo KW, Lim HS, Song R, So JH, Kim CH, Kong YY", "evidence": [ { "database": "UniProtKB", "id": "Q8R516", "url": "https://www.uniprot.org/uniprotkb/Q8R516" }, { "database": "RefSeq", "id": "NP_001243037", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243037" } ], "reference": [ { "type": "PubMed", "id": "15824097", "url": "https://glygen.org/publication/PubMed/15824097" } ] } ], "crossref": [ { "id": "Q8R516", "url": "https://www.uniprot.org/uniprotkb/Q8R516", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "15824097", "url": "https://glygen.org/publication/PubMed/15824097", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "C", "start_aa": "C", "up_seq": "SELALLILFSPCQHRTVCEE", "down_seq": "ARRMKKCIRCQVVISKKLRP", "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "No effect.", "evidence": [ { "database": "UniProtKB", "id": "Q8R516", "url": "https://www.uniprot.org/uniprotkb/Q8R516" }, { "database": "PubMed", "id": "15824097", "url": "https://glygen.org/publication/PubMed/15824097" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "47", "end_pos": "47" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "874", "end_pos": "874" }, { "start_pos": "951", "end_pos": "951" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "251", "end_pos": "251" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8R516-1.951.951", "start_pos": 951, "end_pos": 951, "uniprot_canonical_ac": "Q8R516-1", "length": 973, "uniprot_id": "MIB2_MOUSE", "protein_name": "E3 ubiquitin-protein ligase MIB2", "refseq_ac": "NP_001243037", "refseq_name": "E3 ubiquitin-protein ligase MIB2 isoform 2", "gene_name": "Mib2", "gene_names_uniprotkb": "Mib2; Skd", "gene_names_refseq": "2210008I11Rik; Mib2; Zzank1; skd", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8R516", "url": "https://www.uniprot.org/uniprotkb/Q8R516" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Mind bomb-2 is an E3 ligase for Notch ligand.", "journal": "The Journal of biological chemistry", "date": "2005", "authors": "Koo BK, Yoon KJ, Yoo KW, Lim HS, Song R, So JH, Kim CH, Kong YY", "evidence": [ { "database": "UniProtKB", "id": "Q8R516", "url": "https://www.uniprot.org/uniprotkb/Q8R516" }, { "database": "RefSeq", "id": "NP_001243037", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243037" } ], "reference": [ { "type": "PubMed", "id": "15824097", "url": "https://glygen.org/publication/PubMed/15824097" } ] } ], "crossref": [ { "id": "Q8R516", "url": "https://www.uniprot.org/uniprotkb/Q8R516", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "15824097", "url": "https://glygen.org/publication/PubMed/15824097", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "C", "start_aa": "C", "up_seq": "ICIDSHIRLVFQCGHGACAP", "down_seq": "GAALNACPICRQPIRDRIQI", "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Abolishes ubiquitin ligase activity.", "evidence": [ { "database": "UniProtKB", "id": "Q8R516", "url": "https://www.uniprot.org/uniprotkb/Q8R516" }, { "database": "PubMed", "id": "15824097", "url": "https://glygen.org/publication/PubMed/15824097" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "47", "end_pos": "47" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "874", "end_pos": "874" }, { "start_pos": "951", "end_pos": "951" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "251", "end_pos": "251" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8R516-1.251.251", "start_pos": 251, "end_pos": 251, "uniprot_canonical_ac": "Q8R516-1", "length": 973, "uniprot_id": "MIB2_MOUSE", "protein_name": "E3 ubiquitin-protein ligase MIB2", "refseq_ac": "NP_001243037", "refseq_name": "E3 ubiquitin-protein ligase MIB2 isoform 2", "gene_name": "Mib2", "gene_names_uniprotkb": "Mib2; Skd", "gene_names_refseq": "2210008I11Rik; Mib2; Zzank1; skd", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8R516", "url": "https://www.uniprot.org/uniprotkb/Q8R516" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8R516", "url": "https://www.uniprot.org/uniprotkb/Q8R516", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "FYYKEHLPKLGKPAELQRRV", "down_seq": "ADGQPFQRGDKVKCLLDTDV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8R516", "url": "https://www.uniprot.org/uniprotkb/Q8R516" } ], "site_lbl": "Ser251" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "47", "end_pos": "47" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "874", "end_pos": "874" }, { "start_pos": "951", "end_pos": "951" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "251", "end_pos": "251" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q62425-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "Q62425-1", "length": 82, "uniprot_id": "CXFA4_MOUSE", "protein_name": "Cytochrome c oxidase subunit FA4", "refseq_ac": "NP_035016", "refseq_name": "cytochrome c oxidase subunit FA4", "gene_name": "Coxfa4", "gene_names_uniprotkb": "Coxfa4; Ndufa4", "gene_names_refseq": "Coxfa4; MLRQ; Ndufa4", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q62425", "url": "https://www.uniprot.org/uniprotkb/Q62425" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Hepatocyte-specific O-GlcNAc transferase downregulation ameliorates nonalcoholic steatohepatitis by improving mitochondrial function.", "journal": "Molecular metabolism", "date": "2023-09", "authors": "Gonzalez-Rellan Maria J, Parracho Tamara, Heras Violeta, Rodriguez Amaia, Fondevila Marcos F, Novoa Eva, Lima Natalia, Varela-Rey Marta, Senra Ana, Chantada-Vazquez Maria D P, Ameneiro Cristina, Bernardo Ganeko, Fernandez-Ramos David, Lopitz-Otsoa Fernando, Bilbao Jon, Guallar Diana, Fidalgo Miguel, Bravo Susana, Dieguez Carlos, Martinez-Chantar Maria L, Millet Oscar, Mato Jose M, Schwaninger Markus, Prevot Vincent, Crespo Javier, Fr\u00fchbeck Gema, Iruzubieta Paula, Nogueiras Ruben", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q62425", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q62425" } ], "reference": [ { "type": "PubMed", "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647" } ] }, { "title": "First comprehensive identification of cardiac proteins with putative increased O-GlcNAc levels during pressure overload hypertrophy.", "journal": "PloS one", "date": "2022", "authors": "Zhu Wei Zhong, Palazzo Teresa, Zhou Mowei, Ledee Dolena, Olson Heather M, Pa\u0161a-Toli\u0107 Ljiljana, Olson Aaron K", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q62425", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q62425" } ], "reference": [ { "type": "PubMed", "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343" } ] }, { "title": "Differential Detection of O-GlcNAcylated proteins in the heart using antibodies.", "journal": "Analytical biochemistry", "date": "2023-10-01", "authors": "Narayanan Bhargavi, Zahra Fiddia, Reeves Russell A, Aggarwal Akanksha, O'Meally Robert N, Henry Roger K, Craven Megan, Jacobson Avital, Cole Robert N, Kohr Mark J, Umapathi Priya, Zachara Natasha E", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q62425", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q62425" } ], "reference": [ { "type": "PubMed", "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081" } ] }, { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q62425", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q62425" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] }, { "title": "A reference dataset of O-GlcNAc proteins in quadriceps skeletal muscle from mice.", "journal": "Glycobiology", "date": "2025-02-10", "authors": "Jaiswal Ruchi, Liu Yimin, Petriello Michael, Zhang Xiangmin, Yi Zhengping, Fehl Charlie", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q62425", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q62425" } ], "reference": [ { "type": "PubMed", "id": "39927985", "url": "https://glygen.org/publication/PubMed/39927985" } ] }, { "title": "Dynamic O-GlcNAcylation governs long-range chromatin interactions in V(D)J recombination during early B-cell development.", "journal": "Cellular & molecular immunology", "date": "2025-01", "authors": "Jeon Bong Chan, Kim Yu-Ji, Park Ae Kyung, Song Mi-Ran, Na Ki Myeong, Lee Juwon, An Dasom, Park Yeseul, Hwang Heeyoun, Kim Tae-Don, Lim Junghyun, Park Sung-Kyun", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q62425", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q62425" } ], "reference": [ { "type": "PubMed", "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609" } ] } ], "crossref": [ { "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q62425", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q62425", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343", "database": "PubMed", "categories": [ "Other" ] }, { "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "39927985", "url": "https://glygen.org/publication/PubMed/39927985", "database": "PubMed", "categories": [ "Other" ] }, { "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609", "database": "PubMed", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "37453647", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37453647" }, { "id": "Q62425", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q62425" }, { "id": "36288343", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36288343" }, { "id": "37507081", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37507081" }, { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" }, { "id": "39927985", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39927985" }, { "id": "39627609", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39627609" } ] } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "67", "end_pos": "67" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q62425-1.67.67", "start_pos": 67, "end_pos": 67, "uniprot_canonical_ac": "Q62425-1", "length": 82, "uniprot_id": "CXFA4_MOUSE", "protein_name": "Cytochrome c oxidase subunit FA4", "refseq_ac": "NP_035016", "refseq_name": "cytochrome c oxidase subunit FA4", "gene_name": "Coxfa4", "gene_names_uniprotkb": "Coxfa4; Ndufa4", "gene_names_refseq": "Coxfa4; MLRQ; Ndufa4", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q62425", "url": "https://www.uniprot.org/uniprotkb/Q62425" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q62425", "url": "https://www.uniprot.org/uniprotkb/Q62425" }, { "database": "iPTMnet", "id": "Q62425", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q62425" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q62425", "url": "https://www.uniprot.org/uniprotkb/Q62425", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q62425", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q62425", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RKNNPEPWNKLGPNEQYKFY", "down_seq": "VNVDYSKLKKEGPDF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q62425", "url": "https://www.uniprot.org/uniprotkb/Q62425" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q62425", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q62425" } ], "site_lbl": "Ser67" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "67", "end_pos": "67" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q3UIU2-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "Q3UIU2-1", "length": 128, "uniprot_id": "NDUB6_MOUSE", "protein_name": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6", "refseq_ac": "NP_001028477", "refseq_name": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6", "gene_name": "Ndufb6", "gene_names_uniprotkb": "Ndufb6; Gm137", "gene_names_refseq": "CI-B17; Gm137; Ndufb6", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3UIU2", "url": "https://www.uniprot.org/uniprotkb/Q3UIU2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "First comprehensive identification of cardiac proteins with putative increased O-GlcNAc levels during pressure overload hypertrophy.", "journal": "PloS one", "date": "2022", "authors": "Zhu Wei Zhong, Palazzo Teresa, Zhou Mowei, Ledee Dolena, Olson Heather M, Pa\u0161a-Toli\u0107 Ljiljana, Olson Aaron K", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q3UIU2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3UIU2" } ], "reference": [ { "type": "PubMed", "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343" } ] } ], "crossref": [ { "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q3UIU2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3UIU2", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "36288343", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36288343" }, { "id": "Q3UIU2", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3UIU2" } ] } ], "all_sites": [], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BNJ6-1.311.311", "start_pos": 311, "end_pos": 311, "uniprot_canonical_ac": "Q8BNJ6-1", "length": 525, "uniprot_id": "NETO2_MOUSE", "protein_name": "Neuropilin and tolloid-like protein 2", "refseq_ac": "NP_001074793", "refseq_name": "neuropilin and tolloid-like protein 2 isoform 3", "gene_name": "Neto2", "gene_names_uniprotkb": "Neto2; Btcl2", "gene_names_refseq": "5530601C23Rik; BTCL2; Neto2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BNJ6", "url": "https://www.uniprot.org/uniprotkb/Q8BNJ6" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8BNJ6", "url": "https://www.uniprot.org/uniprotkb/Q8BNJ6", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "SFVEPPCTSSTFFCHSNMCI", "down_seq": "NSLVCNGVQNCAYPWDENHC", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn311", "evidence": [ { "id": "Q8BNJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8BNJ6#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "311", "end_pos": "311" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "409", "end_pos": "409" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8BNJ6-1.409.409", "start_pos": 409, "end_pos": 409, "uniprot_canonical_ac": "Q8BNJ6-1", "length": 525, "uniprot_id": "NETO2_MOUSE", "protein_name": "Neuropilin and tolloid-like protein 2", "refseq_ac": "NP_001074793", "refseq_name": "neuropilin and tolloid-like protein 2 isoform 3", "gene_name": "Neto2", "gene_names_uniprotkb": "Neto2; Btcl2", "gene_names_refseq": "5530601C23Rik; BTCL2; Neto2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BNJ6", "url": "https://www.uniprot.org/uniprotkb/Q8BNJ6" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8BNJ6", "url": "https://www.uniprot.org/uniprotkb/Q8BNJ6" }, { "database": "iPTMnet", "id": "Q8BNJ6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8BNJ6" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q8BNJ6", "url": "https://www.uniprot.org/uniprotkb/Q8BNJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BNJ6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8BNJ6", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "FQEVFDPPHYELFSLREKEI", "down_seq": "ADLADLSEELDNYQKLRRSS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8BNJ6", "url": "https://www.uniprot.org/uniprotkb/Q8BNJ6" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q8BNJ6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8BNJ6" } ], "site_lbl": "Ser409" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "311", "end_pos": "311" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "409", "end_pos": "409" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9CQZ6-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "Q9CQZ6-1", "length": 104, "uniprot_id": "NDUB3_MOUSE", "protein_name": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3", "refseq_ac": "NP_079873", "refseq_name": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3", "gene_name": "Ndufb3", "gene_names_uniprotkb": "Ndufb3", "gene_names_refseq": "2700033I16Rik; CI-B12; Ndufb3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9CQZ6", "url": "https://www.uniprot.org/uniprotkb/Q9CQZ6" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "First comprehensive identification of cardiac proteins with putative increased O-GlcNAc levels during pressure overload hypertrophy.", "journal": "PloS one", "date": "2022", "authors": "Zhu Wei Zhong, Palazzo Teresa, Zhou Mowei, Ledee Dolena, Olson Heather M, Pa\u0161a-Toli\u0107 Ljiljana, Olson Aaron K", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9CQZ6", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9CQZ6" } ], "reference": [ { "type": "PubMed", "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343" } ] } ], "crossref": [ { "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9CQZ6", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9CQZ6", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "36288343", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36288343" }, { "id": "Q9CQZ6", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9CQZ6" } ] } ], "all_sites": [], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D0F1-1.302.302", "start_pos": 302, "end_pos": 302, "uniprot_canonical_ac": "Q9D0F1-1", "length": 642, "uniprot_id": "NDC80_MOUSE", "protein_name": "Kinetochore protein NDC80 homolog", "refseq_ac": "NP_075783", "refseq_name": "kinetochore protein NDC80 homolog", "gene_name": "Ndc80", "gene_names_uniprotkb": "Ndc80; Hec1; Kntc2", "gene_names_refseq": "2610020P18Rik; HEC1; HEC; Kntc2; Ndc80", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D0F1", "url": "https://www.uniprot.org/uniprotkb/Q9D0F1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Quantitative Profiling of Protein O-GlcNAcylation Sites by an Isotope-Tagged Cleavable Linker.", "journal": "ACS chemical biology", "date": "2018", "authors": "Qin K, Zhu Y, Qin W, Gao J, Shao X, Wang YL, Zhou W, Wang C, Chen X", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q9D0F1", "url": "https://oglcnac.org/atlas/detail/Q9D0F1" } ], "reference": [ { "type": "PubMed", "id": "30059200", "url": "https://glygen.org/publication/PubMed/30059200" } ] } ], "crossref": [ { "id": "30059200", "url": "https://glygen.org/publication/PubMed/30059200", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9D0F1", "url": "https://oglcnac.org/atlas/detail/Q9D0F1", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LEEEREREPNRLMSLKKLKA", "down_seq": "LQADVQNYKAYMSNLESHLA", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser302", "evidence": [ { "id": "30059200", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30059200" }, { "id": "Q9D0F1", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q9D0F1" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "302", "end_pos": "302" } ] }, { "type": "snv", "site_list": [ { "start_pos": "274", "end_pos": "274" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "165", "end_pos": "165" }, { "start_pos": "242", "end_pos": "242" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "69", "end_pos": "69" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D0F1-1.274.274", "start_pos": 274, "end_pos": 274, "uniprot_canonical_ac": "Q9D0F1-1", "length": 642, "uniprot_id": "NDC80_MOUSE", "protein_name": "Kinetochore protein NDC80 homolog", "refseq_ac": "NP_075783", "refseq_name": "kinetochore protein NDC80 homolog", "gene_name": "Ndc80", "gene_names_uniprotkb": "Ndc80; Hec1; Kntc2", "gene_names_refseq": "2610020P18Rik; HEC1; HEC; Kntc2; Ndc80", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D0F1", "url": "https://www.uniprot.org/uniprotkb/Q9D0F1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3389427978", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389427978", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "A", "start_aa": "A", "up_seq": "LKDLYKVDASKLESLEAENK", "down_seq": "LNEQIARLEEEREREPNRLM", "snv": [ { "evidence": [ { "id": "rs3389427978", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389427978" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "A", "sequence_mut": "T", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (NKA->NKT).", "chr_id": "17", "chr_pos": "71819438", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "A274", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "302", "end_pos": "302" } ] }, { "type": "snv", "site_list": [ { "start_pos": "274", "end_pos": "274" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "165", "end_pos": "165" }, { "start_pos": "242", "end_pos": "242" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "69", "end_pos": "69" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9D0F1-1.165.165", "start_pos": 165, "end_pos": 165, "uniprot_canonical_ac": "Q9D0F1-1", "length": 642, "uniprot_id": "NDC80_MOUSE", "protein_name": "Kinetochore protein NDC80 homolog", "refseq_ac": "NP_075783", "refseq_name": "kinetochore protein NDC80 homolog", "gene_name": "Ndc80", "gene_names_uniprotkb": "Ndc80; Hec1; Kntc2", "gene_names_refseq": "2610020P18Rik; HEC1; HEC; Kntc2; Ndc80", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D0F1", "url": "https://www.uniprot.org/uniprotkb/Q9D0F1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9D0F1", "url": "https://www.uniprot.org/uniprotkb/Q9D0F1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TKCEEEVPRIFKALGYPFTL", "down_seq": "KSSMYTVGAPHTWPHIVAAL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by NEK2", "evidence": [ { "database": "UniProtKB", "id": "Q9D0F1", "url": "https://www.uniprot.org/uniprotkb/Q9D0F1" } ], "site_lbl": "Ser165" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "302", "end_pos": "302" } ] }, { "type": "snv", "site_list": [ { "start_pos": "274", "end_pos": "274" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "165", "end_pos": "165" }, { "start_pos": "242", "end_pos": "242" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "69", "end_pos": "69" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9D0F1-1.242.242", "start_pos": 242, "end_pos": 242, "uniprot_canonical_ac": "Q9D0F1-1", "length": 642, "uniprot_id": "NDC80_MOUSE", "protein_name": "Kinetochore protein NDC80 homolog", "refseq_ac": "NP_075783", "refseq_name": "kinetochore protein NDC80 homolog", "gene_name": "Ndc80", "gene_names_uniprotkb": "Ndc80; Hec1; Kntc2", "gene_names_refseq": "2610020P18Rik; HEC1; HEC; Kntc2; Ndc80", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D0F1", "url": "https://www.uniprot.org/uniprotkb/Q9D0F1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9D0F1", "url": "https://www.uniprot.org/uniprotkb/Q9D0F1" }, { "database": "iPTMnet", "id": "Q9D0F1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9D0F1" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q9D0F1", "url": "https://www.uniprot.org/uniprotkb/Q9D0F1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9D0F1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9D0F1", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NKLFLEYTKKCYEKFMTGAD", "down_seq": "FEEEDAELQAKLKDLYKVDA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9D0F1", "url": "https://www.uniprot.org/uniprotkb/Q9D0F1" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q9D0F1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9D0F1" } ], "site_lbl": "Ser242" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "302", "end_pos": "302" } ] }, { "type": "snv", "site_list": [ { "start_pos": "274", "end_pos": "274" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "165", "end_pos": "165" }, { "start_pos": "242", "end_pos": "242" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "69", "end_pos": "69" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D0F1-1.44.44", "start_pos": 44, "end_pos": 44, "uniprot_canonical_ac": "Q9D0F1-1", "length": 642, "uniprot_id": "NDC80_MOUSE", "protein_name": "Kinetochore protein NDC80 homolog", "refseq_ac": "NP_075783", "refseq_name": "kinetochore protein NDC80 homolog", "gene_name": "Ndc80", "gene_names_uniprotkb": "Ndc80; Hec1; Kntc2", "gene_names_refseq": "2610020P18Rik; HEC1; HEC; Kntc2; Ndc80", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D0F1", "url": "https://www.uniprot.org/uniprotkb/Q9D0F1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9D0F1", "url": "https://www.uniprot.org/uniprotkb/Q9D0F1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LNKPGLYTPQTKERSTFGKL", "down_seq": "THKPTSERKVSIFGKRTSGH", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9D0F1", "url": "https://www.uniprot.org/uniprotkb/Q9D0F1" } ], "site_lbl": "Ser44" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "302", "end_pos": "302" } ] }, { "type": "snv", "site_list": [ { "start_pos": "274", "end_pos": "274" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "165", "end_pos": "165" }, { "start_pos": "242", "end_pos": "242" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "69", "end_pos": "69" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "upstream", "id": "Q9D0F1-1.55.55", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q9D0F1-1.62.62", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9D0F1-1.55.55", "start_pos": 55, "end_pos": 55, "uniprot_canonical_ac": "Q9D0F1-1", "length": 642, "uniprot_id": "NDC80_MOUSE", "protein_name": "Kinetochore protein NDC80 homolog", "refseq_ac": "NP_075783", "refseq_name": "kinetochore protein NDC80 homolog", "gene_name": "Ndc80", "gene_names_uniprotkb": "Ndc80; Hec1; Kntc2", "gene_names_refseq": "2610020P18Rik; HEC1; HEC; Kntc2; Ndc80", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D0F1", "url": "https://www.uniprot.org/uniprotkb/Q9D0F1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9D0F1", "url": "https://www.uniprot.org/uniprotkb/Q9D0F1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KERSTFGKLSTHKPTSERKV", "down_seq": "IFGKRTSGHGSRNSQLGIFS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9D0F1", "url": "https://www.uniprot.org/uniprotkb/Q9D0F1" } ], "site_lbl": "Ser55" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "302", "end_pos": "302" } ] }, { "type": "snv", "site_list": [ { "start_pos": "274", "end_pos": "274" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "165", "end_pos": "165" }, { "start_pos": "242", "end_pos": "242" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "69", "end_pos": "69" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "Q9D0F1-1.44.44", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q9D0F1-1.62.62", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q9D0F1-1.69.69", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9D0F1-1.62.62", "start_pos": 62, "end_pos": 62, "uniprot_canonical_ac": "Q9D0F1-1", "length": 642, "uniprot_id": "NDC80_MOUSE", "protein_name": "Kinetochore protein NDC80 homolog", "refseq_ac": "NP_075783", "refseq_name": "kinetochore protein NDC80 homolog", "gene_name": "Ndc80", "gene_names_uniprotkb": "Ndc80; Hec1; Kntc2", "gene_names_refseq": "2610020P18Rik; HEC1; HEC; Kntc2; Ndc80", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D0F1", "url": "https://www.uniprot.org/uniprotkb/Q9D0F1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9D0F1", "url": "https://www.uniprot.org/uniprotkb/Q9D0F1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KLSTHKPTSERKVSIFGKRT", "down_seq": "GHGSRNSQLGIFSSSEKIKD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9D0F1", "url": "https://www.uniprot.org/uniprotkb/Q9D0F1" } ], "site_lbl": "Ser62" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "302", "end_pos": "302" } ] }, { "type": "snv", "site_list": [ { "start_pos": "274", "end_pos": "274" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "165", "end_pos": "165" }, { "start_pos": "242", "end_pos": "242" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "69", "end_pos": "69" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "Q9D0F1-1.44.44", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "Q9D0F1-1.55.55", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q9D0F1-1.69.69", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9D0F1-1.69.69", "start_pos": 69, "end_pos": 69, "uniprot_canonical_ac": "Q9D0F1-1", "length": 642, "uniprot_id": "NDC80_MOUSE", "protein_name": "Kinetochore protein NDC80 homolog", "refseq_ac": "NP_075783", "refseq_name": "kinetochore protein NDC80 homolog", "gene_name": "Ndc80", "gene_names_uniprotkb": "Ndc80; Hec1; Kntc2", "gene_names_refseq": "2610020P18Rik; HEC1; HEC; Kntc2; Ndc80", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D0F1", "url": "https://www.uniprot.org/uniprotkb/Q9D0F1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9D0F1", "url": "https://www.uniprot.org/uniprotkb/Q9D0F1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TSERKVSIFGKRTSGHGSRN", "down_seq": "QLGIFSSSEKIKDPRPLNDK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9D0F1", "url": "https://www.uniprot.org/uniprotkb/Q9D0F1" } ], "site_lbl": "Ser69" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "302", "end_pos": "302" } ] }, { "type": "snv", "site_list": [ { "start_pos": "274", "end_pos": "274" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "165", "end_pos": "165" }, { "start_pos": "242", "end_pos": "242" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "69", "end_pos": "69" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "Q9D0F1-1.55.55", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "Q9D0F1-1.62.62", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9ES74-1.170.170", "start_pos": 170, "end_pos": 170, "uniprot_canonical_ac": "Q9ES74-1", "length": 302, "uniprot_id": "NEK7_MOUSE", "protein_name": "Serine/threonine-protein kinase Nek7", "refseq_ac": "NP_001298077", "refseq_name": "serine/threonine-protein kinase Nek7 isoform 2", "gene_name": "Nek7", "gene_names_uniprotkb": "Nek7", "gene_names_refseq": "2810460C19Rik; Nek7", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ES74", "url": "https://www.uniprot.org/uniprotkb/Q9ES74" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation Mediated by OGA Activates NEK7/NLRP3 Pathway to Promote Pyroptosis in Parkinson's Disease.", "journal": "Journal of cellular and molecular medicine", "date": "2025-10", "authors": "Wang Zhi, Liu Yue, Ma Lili, Sun Hongwei, Tang Ying", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9ES74", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9ES74" } ], "reference": [ { "type": "PubMed", "id": "41066511", "url": "https://glygen.org/publication/PubMed/41066511" } ] }, { "title": "The Small Molecule 2-Azido-2-deoxy-glucose Is a Metabolic Chemical Reporter of O-GlcNAc Modifications in Mammalian Cells, Revealing an Unexpected Promiscuity of O-GlcNAc Transferase.", "journal": "ACS chemical biology", "date": "2017", "authors": "Zaro BW, Batt AR, Chuh KN, Navarro MX, Pratt MR", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9ES74", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9ES74" } ], "reference": [ { "type": "PubMed", "id": "28135057", "url": "https://glygen.org/publication/PubMed/28135057" } ] } ], "crossref": [ { "id": "41066511", "url": "https://glygen.org/publication/PubMed/41066511", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9ES74", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9ES74", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "28135057", "url": "https://glygen.org/publication/PubMed/28135057", "database": "PubMed", "categories": [ "Other" ] }, { "id": "rs3388505603", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388505603", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "DHMHSRRVMHRDIKPANVFI", "down_seq": "ATGVVKLGDLGLGRFFSSKT", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr170", "evidence": [ { "id": "41066511", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/41066511" }, { "id": "Q9ES74", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9ES74" }, { "id": "28135057", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/28135057" } ] } ], "snv": [ { "evidence": [ { "id": "rs3388505603", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388505603" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "T", "sequence_mut": "R", "comment": "Germline mutation passed 1 filters: o-glyco-site-loss (T->R).", "chr_id": "1", "chr_pos": "138443443", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "T170", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "170", "end_pos": "170" }, { "start_pos": "172", "end_pos": "172" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "63", "end_pos": "63" }, { "start_pos": "63", "end_pos": "64" }, { "start_pos": "64", "end_pos": "64" } ] }, { "type": "snv", "site_list": [ { "start_pos": "170", "end_pos": "170" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "195", "end_pos": "195" }, { "start_pos": "5", "end_pos": "5" } ] } ], "categories": [ "glycosylation_flag", "snv_flag" ], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "Q9ES74-1.172.172", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9ES74-1.172.172", "start_pos": 172, "end_pos": 172, "uniprot_canonical_ac": "Q9ES74-1", "length": 302, "uniprot_id": "NEK7_MOUSE", "protein_name": "Serine/threonine-protein kinase Nek7", "refseq_ac": "NP_001298077", "refseq_name": "serine/threonine-protein kinase Nek7 isoform 2", "gene_name": "Nek7", "gene_names_uniprotkb": "Nek7", "gene_names_refseq": "2810460C19Rik; Nek7", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ES74", "url": "https://www.uniprot.org/uniprotkb/Q9ES74" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation Mediated by OGA Activates NEK7/NLRP3 Pathway to Promote Pyroptosis in Parkinson's Disease.", "journal": "Journal of cellular and molecular medicine", "date": "2025-10", "authors": "Wang Zhi, Liu Yue, Ma Lili, Sun Hongwei, Tang Ying", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9ES74", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9ES74" } ], "reference": [ { "type": "PubMed", "id": "41066511", "url": "https://glygen.org/publication/PubMed/41066511" } ] }, { "title": "The Small Molecule 2-Azido-2-deoxy-glucose Is a Metabolic Chemical Reporter of O-GlcNAc Modifications in Mammalian Cells, Revealing an Unexpected Promiscuity of O-GlcNAc Transferase.", "journal": "ACS chemical biology", "date": "2017", "authors": "Zaro BW, Batt AR, Chuh KN, Navarro MX, Pratt MR", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9ES74", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9ES74" } ], "reference": [ { "type": "PubMed", "id": "28135057", "url": "https://glygen.org/publication/PubMed/28135057" } ] } ], "crossref": [ { "id": "41066511", "url": "https://glygen.org/publication/PubMed/41066511", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9ES74", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9ES74", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "28135057", "url": "https://glygen.org/publication/PubMed/28135057", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "MHSRRVMHRDIKPANVFITA", "down_seq": "GVVKLGDLGLGRFFSSKTTA", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr172", "evidence": [ { "id": "41066511", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/41066511" }, { "id": "Q9ES74", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9ES74" }, { "id": "28135057", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/28135057" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "170", "end_pos": "170" }, { "start_pos": "172", "end_pos": "172" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "63", "end_pos": "63" }, { "start_pos": "63", "end_pos": "64" }, { "start_pos": "64", "end_pos": "64" } ] }, { "type": "snv", "site_list": [ { "start_pos": "170", "end_pos": "170" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "195", "end_pos": "195" }, { "start_pos": "5", "end_pos": "5" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "Q9ES74-1.170.170", "categories": [ "glycosylation_flag", "snv_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9ES74-1.63.63", "start_pos": 63, "end_pos": 63, "uniprot_canonical_ac": "Q9ES74-1", "length": 302, "uniprot_id": "NEK7_MOUSE", "protein_name": "Serine/threonine-protein kinase Nek7", "refseq_ac": "NP_001298077", "refseq_name": "serine/threonine-protein kinase Nek7 isoform 2", "gene_name": "Nek7", "gene_names_uniprotkb": "Nek7", "gene_names_refseq": "2810460C19Rik; Nek7", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ES74", "url": "https://www.uniprot.org/uniprotkb/Q9ES74" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux.", "journal": "Nature", "date": "2016", "authors": "He Y, Zeng MY, Yang D, Motro B, Nunez G", "evidence": [ { "database": "UniProtKB", "id": "Q9ES74", "url": "https://www.uniprot.org/uniprotkb/Q9ES74" } ], "reference": [ { "type": "PubMed", "id": "26814970", "url": "https://glygen.org/publication/PubMed/26814970" } ] } ], "crossref": [ { "id": "Q9ES74", "url": "https://www.uniprot.org/uniprotkb/Q9ES74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "26814970", "url": "https://glygen.org/publication/PubMed/26814970", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "GQFSEVYRASCLLDGVPVAL", "down_seq": "KVQIFDLMDAKARADCIKEI", "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "M", "comment": "No effect on interaction with NLRP3.", "evidence": [ { "database": "UniProtKB", "id": "Q9ES74", "url": "https://www.uniprot.org/uniprotkb/Q9ES74" }, { "database": "PubMed", "id": "26814970", "url": "https://glygen.org/publication/PubMed/26814970" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "170", "end_pos": "170" }, { "start_pos": "172", "end_pos": "172" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "63", "end_pos": "63" }, { "start_pos": "63", "end_pos": "64" }, { "start_pos": "64", "end_pos": "64" } ] }, { "type": "snv", "site_list": [ { "start_pos": "170", "end_pos": "170" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "195", "end_pos": "195" }, { "start_pos": "5", "end_pos": "5" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 0, "direction": "upstream", "id": "Q9ES74-1.63.64", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q9ES74-1.64.64", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9ES74-1.63.64", "start_pos": 63, "end_pos": 64, "uniprot_canonical_ac": "Q9ES74-1", "length": 302, "uniprot_id": "NEK7_MOUSE", "protein_name": "Serine/threonine-protein kinase Nek7", "refseq_ac": "NP_001298077", "refseq_name": "serine/threonine-protein kinase Nek7 isoform 2", "gene_name": "Nek7", "gene_names_uniprotkb": "Nek7", "gene_names_refseq": "2810460C19Rik; Nek7", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ES74", "url": "https://www.uniprot.org/uniprotkb/Q9ES74" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux.", "journal": "Nature", "date": "2016", "authors": "He Y, Zeng MY, Yang D, Motro B, Nunez G", "evidence": [ { "database": "UniProtKB", "id": "Q9ES74", "url": "https://www.uniprot.org/uniprotkb/Q9ES74" } ], "reference": [ { "type": "PubMed", "id": "26814970", "url": "https://glygen.org/publication/PubMed/26814970" } ] } ], "crossref": [ { "id": "Q9ES74", "url": "https://www.uniprot.org/uniprotkb/Q9ES74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "26814970", "url": "https://glygen.org/publication/PubMed/26814970", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "KK", "start_aa": "K", "up_seq": "GQFSEVYRASCLLDGVPVAL", "down_seq": "VQIFDLMDAKARADCIKEID", "mutagenesis": [ { "sequence_org": "KK", "sequence_mut": "MM", "comment": "No effect on interaction with NLRP3.", "evidence": [ { "database": "UniProtKB", "id": "Q9ES74", "url": "https://www.uniprot.org/uniprotkb/Q9ES74" }, { "database": "PubMed", "id": "26814970", "url": "https://glygen.org/publication/PubMed/26814970" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "170", "end_pos": "170" }, { "start_pos": "172", "end_pos": "172" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "63", "end_pos": "63" }, { "start_pos": "63", "end_pos": "64" }, { "start_pos": "64", "end_pos": "64" } ] }, { "type": "snv", "site_list": [ { "start_pos": "170", "end_pos": "170" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "195", "end_pos": "195" }, { "start_pos": "5", "end_pos": "5" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 0, "direction": "downstream", "id": "Q9ES74-1.63.63", "categories": [ "mutagenesis_flag" ] }, { "distance": 0, "direction": "upstream", "id": "Q9ES74-1.64.64", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9ES74-1.64.64", "start_pos": 64, "end_pos": 64, "uniprot_canonical_ac": "Q9ES74-1", "length": 302, "uniprot_id": "NEK7_MOUSE", "protein_name": "Serine/threonine-protein kinase Nek7", "refseq_ac": "NP_001298077", "refseq_name": "serine/threonine-protein kinase Nek7 isoform 2", "gene_name": "Nek7", "gene_names_uniprotkb": "Nek7", "gene_names_refseq": "2810460C19Rik; Nek7", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ES74", "url": "https://www.uniprot.org/uniprotkb/Q9ES74" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux.", "journal": "Nature", "date": "2016", "authors": "He Y, Zeng MY, Yang D, Motro B, Nunez G", "evidence": [ { "database": "UniProtKB", "id": "Q9ES74", "url": "https://www.uniprot.org/uniprotkb/Q9ES74" } ], "reference": [ { "type": "PubMed", "id": "26814970", "url": "https://glygen.org/publication/PubMed/26814970" } ] } ], "crossref": [ { "id": "Q9ES74", "url": "https://www.uniprot.org/uniprotkb/Q9ES74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "26814970", "url": "https://glygen.org/publication/PubMed/26814970", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "QFSEVYRASCLLDGVPVALK", "down_seq": "VQIFDLMDAKARADCIKEID", "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "M", "comment": "No effect on interaction with NLRP3.", "evidence": [ { "database": "UniProtKB", "id": "Q9ES74", "url": "https://www.uniprot.org/uniprotkb/Q9ES74" }, { "database": "PubMed", "id": "26814970", "url": "https://glygen.org/publication/PubMed/26814970" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "170", "end_pos": "170" }, { "start_pos": "172", "end_pos": "172" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "63", "end_pos": "63" }, { "start_pos": "63", "end_pos": "64" }, { "start_pos": "64", "end_pos": "64" } ] }, { "type": "snv", "site_list": [ { "start_pos": "170", "end_pos": "170" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "195", "end_pos": "195" }, { "start_pos": "5", "end_pos": "5" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "Q9ES74-1.63.63", "categories": [ "mutagenesis_flag" ] }, { "distance": 0, "direction": "downstream", "id": "Q9ES74-1.63.64", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9ES74-1.195.195", "start_pos": 195, "end_pos": 195, "uniprot_canonical_ac": "Q9ES74-1", "length": 302, "uniprot_id": "NEK7_MOUSE", "protein_name": "Serine/threonine-protein kinase Nek7", "refseq_ac": "NP_001298077", "refseq_name": "serine/threonine-protein kinase Nek7 isoform 2", "gene_name": "Nek7", "gene_names_uniprotkb": "Nek7", "gene_names_refseq": "2810460C19Rik; Nek7", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ES74", "url": "https://www.uniprot.org/uniprotkb/Q9ES74" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9ES74", "url": "https://www.uniprot.org/uniprotkb/Q9ES74", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VKLGDLGLGRFFSSKTTAAH", "down_seq": "LVGTPYYMSPERIHENGYNF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by NEK9", "evidence": [ { "database": "UniProtKB", "id": "Q9ES74", "url": "https://www.uniprot.org/uniprotkb/Q9ES74" } ], "site_lbl": "Ser195" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "170", "end_pos": "170" }, { "start_pos": "172", "end_pos": "172" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "63", "end_pos": "63" }, { "start_pos": "63", "end_pos": "64" }, { "start_pos": "64", "end_pos": "64" } ] }, { "type": "snv", "site_list": [ { "start_pos": "170", "end_pos": "170" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "195", "end_pos": "195" }, { "start_pos": "5", "end_pos": "5" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9ES74-1.5.5", "start_pos": 5, "end_pos": 5, "uniprot_canonical_ac": "Q9ES74-1", "length": 302, "uniprot_id": "NEK7_MOUSE", "protein_name": "Serine/threonine-protein kinase Nek7", "refseq_ac": "NP_001298077", "refseq_name": "serine/threonine-protein kinase Nek7 isoform 2", "gene_name": "Nek7", "gene_names_uniprotkb": "Nek7", "gene_names_refseq": "2810460C19Rik; Nek7", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ES74", "url": "https://www.uniprot.org/uniprotkb/Q9ES74" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9ES74", "url": "https://www.uniprot.org/uniprotkb/Q9ES74", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MDEQ", "down_seq": "QGMQGPPVTQFQPQKALRPD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9ES74", "url": "https://www.uniprot.org/uniprotkb/Q9ES74" } ], "site_lbl": "Ser5" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "170", "end_pos": "170" }, { "start_pos": "172", "end_pos": "172" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "63", "end_pos": "63" }, { "start_pos": "63", "end_pos": "64" }, { "start_pos": "64", "end_pos": "64" } ] }, { "type": "snv", "site_list": [ { "start_pos": "170", "end_pos": "170" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "195", "end_pos": "195" }, { "start_pos": "5", "end_pos": "5" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9JHW2-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "Q9JHW2-1", "length": 276, "uniprot_id": "NIT2_MOUSE", "protein_name": "Omega-amidase NIT2", "refseq_ac": "NP_075664", "refseq_name": "omega-amidase NIT2", "gene_name": "Nit2", "gene_names_uniprotkb": "Nit2; D16Ertd502e", "gene_names_refseq": "1190017B19Rik; D16Ertd502e; Nit2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9JHW2", "url": "https://www.uniprot.org/uniprotkb/Q9JHW2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Hepatocyte-specific O-GlcNAc transferase downregulation ameliorates nonalcoholic steatohepatitis by improving mitochondrial function.", "journal": "Molecular metabolism", "date": "2023-09", "authors": "Gonzalez-Rellan Maria J, Parracho Tamara, Heras Violeta, Rodriguez Amaia, Fondevila Marcos F, Novoa Eva, Lima Natalia, Varela-Rey Marta, Senra Ana, Chantada-Vazquez Maria D P, Ameneiro Cristina, Bernardo Ganeko, Fernandez-Ramos David, Lopitz-Otsoa Fernando, Bilbao Jon, Guallar Diana, Fidalgo Miguel, Bravo Susana, Dieguez Carlos, Martinez-Chantar Maria L, Millet Oscar, Mato Jose M, Schwaninger Markus, Prevot Vincent, Crespo Javier, Fr\u00fchbeck Gema, Iruzubieta Paula, Nogueiras Ruben", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9JHW2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9JHW2" } ], "reference": [ { "type": "PubMed", "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647" } ] }, { "title": "A reference dataset of O-GlcNAc proteins in quadriceps skeletal muscle from mice.", "journal": "Glycobiology", "date": "2025-02-10", "authors": "Jaiswal Ruchi, Liu Yimin, Petriello Michael, Zhang Xiangmin, Yi Zhengping, Fehl Charlie", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9JHW2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9JHW2" } ], "reference": [ { "type": "PubMed", "id": "39927985", "url": "https://glygen.org/publication/PubMed/39927985" } ] }, { "title": "Differential Detection of O-GlcNAcylated proteins in the heart using antibodies.", "journal": "Analytical biochemistry", "date": "2023-10-01", "authors": "Narayanan Bhargavi, Zahra Fiddia, Reeves Russell A, Aggarwal Akanksha, O'Meally Robert N, Henry Roger K, Craven Megan, Jacobson Avital, Cole Robert N, Kohr Mark J, Umapathi Priya, Zachara Natasha E", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9JHW2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9JHW2" } ], "reference": [ { "type": "PubMed", "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081" } ] } ], "crossref": [ { "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9JHW2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9JHW2", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "39927985", "url": "https://glygen.org/publication/PubMed/39927985", "database": "PubMed", "categories": [ "Other" ] }, { "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081", "database": "PubMed", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "37453647", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37453647" }, { "id": "Q9JHW2", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9JHW2" }, { "id": "39927985", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39927985" }, { "id": "37507081", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37507081" } ] } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "26", "end_pos": "26" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9JHW2-1.26.26", "start_pos": 26, "end_pos": 26, "uniprot_canonical_ac": "Q9JHW2-1", "length": 276, "uniprot_id": "NIT2_MOUSE", "protein_name": "Omega-amidase NIT2", "refseq_ac": "NP_075664", "refseq_name": "omega-amidase NIT2", "gene_name": "Nit2", "gene_names_uniprotkb": "Nit2; D16Ertd502e", "gene_names_refseq": "1190017B19Rik; D16Ertd502e; Nit2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9JHW2", "url": "https://www.uniprot.org/uniprotkb/Q9JHW2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9JHW2", "url": "https://www.uniprot.org/uniprotkb/Q9JHW2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LALIQLQVSSIKSDNLTRAC", "down_seq": "LVREAAKQGANIVSLPECFN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9JHW2", "url": "https://www.uniprot.org/uniprotkb/Q9JHW2" } ], "site_lbl": "Ser26" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "26", "end_pos": "26" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P11725-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "P11725-1", "length": 354, "uniprot_id": "OTC_MOUSE", "protein_name": "Ornithine transcarbamylase, mitochondrial", "refseq_ac": "NP_032795", "refseq_name": "ornithine transcarbamylase, mitochondrial isoform 1 precursor", "gene_name": "Otc", "gene_names_uniprotkb": "Otc", "gene_names_refseq": "Otc; Sf; spf", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P11725", "url": "https://www.uniprot.org/uniprotkb/P11725" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Hepatocyte-specific O-GlcNAc transferase downregulation ameliorates nonalcoholic steatohepatitis by improving mitochondrial function.", "journal": "Molecular metabolism", "date": "2023-09", "authors": "Gonzalez-Rellan Maria J, Parracho Tamara, Heras Violeta, Rodriguez Amaia, Fondevila Marcos F, Novoa Eva, Lima Natalia, Varela-Rey Marta, Senra Ana, Chantada-Vazquez Maria D P, Ameneiro Cristina, Bernardo Ganeko, Fernandez-Ramos David, Lopitz-Otsoa Fernando, Bilbao Jon, Guallar Diana, Fidalgo Miguel, Bravo Susana, Dieguez Carlos, Martinez-Chantar Maria L, Millet Oscar, Mato Jose M, Schwaninger Markus, Prevot Vincent, Crespo Javier, Fr\u00fchbeck Gema, Iruzubieta Paula, Nogueiras Ruben", "evidence": [ { "database": "O-GlcNAc Database", "id": "P11725", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P11725" } ], "reference": [ { "type": "PubMed", "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647" } ] } ], "crossref": [ { "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P11725", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P11725", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "37453647", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37453647" }, { "id": "P11725", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P11725" } ] } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "133", "end_pos": "133" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P11725-1.133.133", "start_pos": 133, "end_pos": 133, "uniprot_canonical_ac": "P11725-1", "length": 354, "uniprot_id": "OTC_MOUSE", "protein_name": "Ornithine transcarbamylase, mitochondrial", "refseq_ac": "NP_032795", "refseq_name": "ornithine transcarbamylase, mitochondrial isoform 1 precursor", "gene_name": "Otc", "gene_names_uniprotkb": "Otc", "gene_names_refseq": "Otc; Sf; spf", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P11725", "url": "https://www.uniprot.org/uniprotkb/P11725" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P11725", "url": "https://www.uniprot.org/uniprotkb/P11725", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TQDIHLGVNESLTDTARVLS", "down_seq": "MTDAVLARVYKQSDLDTLAK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P11725", "url": "https://www.uniprot.org/uniprotkb/P11725" } ], "site_lbl": "Ser133" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "133", "end_pos": "133" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P22091-1.122.122", "start_pos": 122, "end_pos": 122, "uniprot_canonical_ac": "P22091-1", "length": 329, "uniprot_id": "TAL1_MOUSE", "protein_name": "T-cell acute lymphocytic leukemia protein 1 homolog", "refseq_ac": "NP_001274317", "refseq_name": "T-cell acute lymphocytic leukemia protein 1 homolog", "gene_name": "Tal1", "gene_names_uniprotkb": "Tal1; Scl; Tal-1", "gene_names_refseq": "Hpt; SCL/tal-1; Scl; Tal1; bHLHa17; tal-1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P22091", "url": "https://www.uniprot.org/uniprotkb/P22091" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Phosphorylation by mitogen-activated protein kinase mediates the hypoxia-induced turnover of the TAL1/SCL transcription factor in endothelial cells.", "journal": "The Journal of biological chemistry", "date": "2002", "authors": "Tang T, Arbiser JL, Brandt SJ", "evidence": [ { "database": "UniProtKB", "id": "P22091", "url": "https://www.uniprot.org/uniprotkb/P22091" }, { "database": "iPTMnet", "id": "P22091", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22091" } ], "reference": [ { "type": "PubMed", "id": "11904294", "url": "https://glygen.org/publication/PubMed/11904294" } ] }, { "title": "Mitogen-activated protein kinase mediates erythropoietin-induced phosphorylation of the TAL1/SCL transcription factor in murine proerythroblasts.", "journal": "The Biochemical journal", "date": "1999", "authors": "Tang T, Prasad KS, Koury MJ, Brandt SJ", "evidence": [ { "database": "iPTMnet", "id": "P22091", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22091" } ], "reference": [ { "type": "PubMed", "id": "10527940", "url": "https://glygen.org/publication/PubMed/10527940" } ] }, { "title": "The vascular bone marrow niche influences outcome in chronic myeloid leukemia via the E-selectin - SCL/TAL1 - CD44 axis.", "journal": "Haematologica", "date": "2020-01", "authors": "Godavarthy Parimala Sonika, Kumar Rahul, Herkt Stefanie C, Pereira Raquel S, Hayduk Nina, Weissenberger Eva S, Aggoune Djamel, Manavski Yosif, Lucas Tina, Pan Kuan-Ting, Voutsinas Jenna M, Wu Qian, M\u00fcller Martin C, Saussele Susanne, Oellerich Thomas, Oehler Vivian G, Lausen Joern, Krause Daniela S", "evidence": [ { "database": "iPTMnet", "id": "P22091", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22091" } ], "reference": [ { "type": "PubMed", "id": "31018977", "url": "https://glygen.org/publication/PubMed/31018977" } ] } ], "crossref": [ { "id": "P22091", "url": "https://www.uniprot.org/uniprotkb/P22091", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "11904294", "url": "https://glygen.org/publication/PubMed/11904294", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22091", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22091", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "10527940", "url": "https://glygen.org/publication/PubMed/10527940", "database": "PubMed", "categories": [ "Other" ] }, { "id": "31018977", "url": "https://glygen.org/publication/PubMed/31018977", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "APAPASAPAELPGDGRMVQL", "down_seq": "PPALAAPAGPGRALLYSLSQ", "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Remains stable, even in the face of severe hypoxia.", "evidence": [ { "database": "UniProtKB", "id": "P22091", "url": "https://www.uniprot.org/uniprotkb/P22091" }, { "database": "PubMed", "id": "11904294", "url": "https://glygen.org/publication/PubMed/11904294" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by MAPK", "evidence": [ { "database": "UniProtKB", "id": "P22091", "url": "https://www.uniprot.org/uniprotkb/P22091" }, { "database": "iPTMnet", "id": "P22091", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22091" }, { "database": "PubMed", "id": "10527940", "url": "https://glygen.org/publication/PubMed/10527940" }, { "database": "PubMed", "id": "11904294", "url": "https://glygen.org/publication/PubMed/11904294" }, { "database": "PubMed", "id": "31018977", "url": "https://glygen.org/publication/PubMed/31018977" } ], "site_lbl": "Ser122" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "122", "end_pos": "122" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "122", "end_pos": "122" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "mutagenesis_flag", "phosphorylation_flag" ], "glycosylation": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] } ]